Designer Drugs: Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.Performance-Enhancing Substances: Agents that improve the ability to carry out activities such as athletics, mental endurance, work, and resistance to stress. The substances can include PRESCRIPTION DRUGS; DIETARY SUPPLEMENTS; phytochemicals; and ILLICIT DRUGS.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Doping in Sports: Illegitimate use of substances for a desired effect in competitive sports. It includes humans and animals.Psychotropic Drugs: A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).Substance Abuse Detection: Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.3,4-Methylenedioxyamphetamine: An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Organizations, Nonprofit: Organizations which are not operated for a profit and may be supported by endowments or private contributions.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.MedlinePlus: NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Confidentiality: The privacy of information and its protection against unauthorized disclosure.Decision Making: The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.Moral Obligations: Duties that are based in ETHICS, rather than in law.Legislation as Topic: The enactment of laws and ordinances and their regulation by official organs of a nation, state, or other legislative organization. It refers also to health-related laws and regulations in general or for which there is no specific heading.Insurance Benefits: Payments or services provided under stated circumstances under the terms of an insurance policy. In prepayment programs, benefits are the services the programs will provide at defined locations and to the extent needed.Legislation, Medical: Laws and regulations, pertaining to the field of medicine, proposed for enactment or enacted by a legislative body.United StatesNarcissism: A psychoanalytic term meaning self-love.Criminal Law: A branch of law that defines criminal offenses, regulates the apprehension, charging and trial of suspected persons, and fixes the penalties and modes of treatment applicable to convicted offenders.Criminals: Persons who have committed a crime or have been convicted of a crime.Criminal Psychology: The branch of psychology which investigates the psychology of crime with particular reference to the personality factors of the criminal.Crime: A violation of the criminal law, i.e., a breach of the conduct code specifically sanctioned by the state, which through its administrative agencies prosecutes offenders and imposes and administers punishments. The concept includes unacceptable actions whether prosecuted or going unpunished.Blogging: Using an INTERNET based personal journal which may consist of reflections, comments, and often hyperlinks.Law Enforcement: Organized efforts to insure obedience to the laws of a community.Insanity Defense: A legal concept that an accused is not criminally responsible if, at the time of committing the act, the person was laboring under such a defect of reason from disease of the mind as not to know the nature and quality of the act done or if the act was known, to not have known that what was done was wrong. (From Black's Law Dictionary, 6th ed)Hallucinogens: Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.Fraud: Exploitation through misrepresentation of the facts or concealment of the purposes of the exploiter.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Peer Review, Research: The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.Writing: The act or practice of literary composition, the occupation of writer, or producing or engaging in literary work as a profession.Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Mescaline: Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.Ethics, Business: The moral obligations governing the conduct of commercial or industrial enterprises.UtopiasLiterature, ModernBeauty: Characteristics or attributes of persons or things which elicit pleasurable feelings.Manufactured Materials: Substances and materials manufactured for use in various technologies and industries and for domestic use.BooksLysergic Acid Diethylamide: Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.N,N-Dimethyltryptamine: An N-methylated indoleamine derivative and serotonergic hallucinogen which occurs naturally and ubiquitously in several plant species including Psychotria veridis. It also occurs in trace amounts in mammalian brain, blood, and urine, and is known to act as an agonist or antagonist of certain SEROTONIN RECEPTORS.Tryptamines: Decarboxylated monoamine derivatives of TRYPTOPHAN.Psilocybine: The major of two hallucinogenic components of Teonanacatl, the sacred mushroom of Mexico, the other component being psilocin. (From Merck Index, 11th ed)Harmaline: A beta-carboline alkaloid isolated from seeds of PEGANUM.IndophenolReceptor, Serotonin, 5-HT2A: A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.Diterpenes, Clerodane: A group of DITERPENES cyclized into 2-rings with a side-chain.PropiophenonesHypoglycins: Methylene cyclopropyl alanine and congeners isolated from the unripe edible fruit of the AKEE plant (BLIGHIA SAPIDA). Hypoglycin B is the gamma-glutamyl congener of hypoglycin A. They are very toxic and teratogenic, causing a syndrome called Jamaican vomiting sickness that includes a fall in blood glucose due to the interference of FATTY ACIDS and LEUCINE metabolism which leads to VOMITING, liver damage, CONVULSIONS and DEATH.Mitragyna: A plant genus of the family RUBIACEAE. Members contain antimalarial (ANTIMALARIALS) and analgesic (ANALGESICS) indole alkaloids.Alkaloids: Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
42 (4): 223-4. doi:10.1016/S1355-0306(02)71832-7. PMID 12632938. de Boer D, Bosman I (2004). "A new trend in drugs-of-abuse; ... 43 (5): 1615-21. doi:10.1016/j.jpba.2006.11.037. PMID 17207601. Venhuis BJ, Blok-Tip L, de Kaste D (2008). "Designer drugs in ... Some compounds such as 2C-B and 5-Meo-DiPT did eventually increase in popularity to the point that they were sold in pill form ... 5 November 2009. "2009 Annual report: the state of the drugs problem in Europe" (PDF). Lisbon: European Monitoring Centre for ...
In Season 4, Episode 8 of The Gilmore Girls, Lorelai states "Going with the flow? Oh, that's so strum your sitar, dig the ... His ashes were placed on the soundboard at the Grateful Dead 50th anniversary shows in Chicago, on July 3-5, 2015. Owsley's ... "Complete transcript of Donald Fagen and Walter Becker in a BBC-Online Chat, March 4, 2000". BBC. 2000-03-04. Retrieved 2010-05- ... ISBN 1-58008-547-4. Perry, Charles (1984). The Haight-Ashbury: A History (pdf). Random House. ISBN 0-394-41098-X. Retrieved ...
... , or 4-bromo-2,5-dimethoxy-N-methylamphetamine, is a lesser-known psychedelic drug. It is similar in structure to DOB ...
2-TOM and 5-TOM are the 2- and 5-methylthio analogs of 2,5-dimethoxy-4-methylamphetamine (DOM), respectively. They were first ... 2-TOM entry in PiHKAL 5-TOM entry in PiHKAL. ...
26 (5): 274-281. doi:10.1016/j.tips.2005.03.007. PMID 15860375. Wang X, Li J, Dong G, Yue J (February 2014). "The endogenous ... 2) ... It deaminates primary and secondary amines that are free in the neuronal cytoplasm but not those bound in storage ... 26 (5): 274-281. doi:10.1016/j.tips.2005.03.007. PMID 15860375. The pharmacology of TAs might also contribute to a molecular ... 116 (2): 164-176. doi:10.1111/j.1471-4159.2010.07109.x. PMC 3005101 . PMID 21073468. Gozal EA, O'Neill BE, Sawchuk MA, Zhu H, ...
5-Dimethoxy-4-methylamphetamine Sustainability and transformation plan, a scheme in NHS England Shovel test pit, a method of ... a shooting sport Sewage treatment plant 2,5-Dimethoxy-4-methylamphetamine, a psychedelic drug also known as DOM or STP. ...
The molecular formula C12H19NO2 (molar mass: 209.28 g/mol, exact mass: 209.141579) may refer to: Bamethan 2C-E 2C-G 2,5- ... Dimethoxy-4-methylamphetamine Methyl-DMA Mirogabalin Octyl cyanoacrylate 2-Octyl cyanoacrylate Psi-DOM. ...
4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide MeSH D02.092.146.325 --- p-dimethylaminoazobenzene MeSH ... vitamin k 2 MeSH D02.455.849.291.523.500.922 --- vitamin k 3 MeSH D02.455.849.291.850 --- taxoids MeSH D02.455.849.291.850.777 ... 5-amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole MeSH D02.640.600.290 --- fanft MeSH D02.640.600.308 --- furagin MeSH ... 2,3-diketogulonic acid MeSH D02.241.081.844.300 --- glucaric acid MeSH D02.241.081.844.322 --- gluconates MeSH D02.241.081.844. ...
... dl-2,5-dimethoxy-4-methylamphetamine a.k.a. DOM), entactogens (e.g., 3,4-methylenedioxyamphetamine a.k.a. MDA), appetite ...
Nichols, D.E., Hoffman, A.J., Oberlender, R.A., Jacob P 3rd & Shulgin A.T. Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine ... 5-(2-Aminopropyl)-2,3-dihydro-1H-indene (5-APDI, IAP) 6-(2-Aminopropyl)benzofuran (6-APB) (benzofury) 5-(2-aminopropyl) ... 4 (1). Retrieved 8 January 2015. Malamud,, Ozer, Yvette; Yuri,, Ito, (2010-01-01). Encyclopedia of emotion. Greenwood Press. ... 191 (2): 181-193. doi:10.1007/s00213-007-0703-5. ISSN 0033-3158. F.,, Quenzer, Linda. Psychopharmacology : drugs, the brain, ...
4)‎ . . Night of Champions (2010) ‎ (→‎Results) *12:39, 10 December 2010 (diff , hist) . . (0)‎ . . Dalek ‎ (→‎Movement: (minor ... 2)‎ . . Shao Kahn ‎ (→‎Origins) *12:41, 14 November 2010 (diff , hist) . . (0)‎ . . Scouting in Alabama ‎ (→‎Black Warrior ... 2)‎ . . Grit (newspaper) ‎ (→‎Comic strips: minor spelling correction) *15:43, 14 June 2010 (diff , hist) . . (-5)‎ . . Matt ... 12:16, 2 June 2010 (diff , hist) . . (+10)‎ . . Washington Naval Treaty ‎ (→‎Terms: grammar...missing word in the sentence) ...
6-dimethoxy positional isomer of DOM, known as Ψ-DOM, is also mentioned in PiHKAL as being active, as is the alpha-ethyl ... Both the 2- and 5- O-desmethyl derivatives 2-DM-DOM and 5-DM-DOM, and the 2- and 5- ethyl analogues 2-Et-DOM and 5-Et-DOM have ... 2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a ... DOM is a chiral molecule, and R-(−)-DOM is the more active enantiomer, functioning as a potent agonist of the serotonin 5-HT ...
Missing or empty ,title= (help) [1] (in Dutch) [2] on the official website of the Dutch government. ... No advertisement No hard drugs No entrance to coffee shops by persons under the age of 18 No sale of more than 5 grams of ... 4-hydroxybutyric acid) hemp oil (concentrate of plants from the Cannabis species (hemp) obtained by extraction of hemp or ... 4,5-trimethoxyamfetamine) zipeprol The esters and derivatives of ecgonine, which can be turned into ecgonine and cocaine; The ...
The compounds of this class are potent and long-lasting psychedelic drugs, and act as highly selective 5-HT2A, 5-HT2B, and 5- ... 4-substituted-2,5-Dimethoxyamphetamines (DOx) is a chemical class of substituted amphetamine derivatives featuring methoxy ... The DOx family includes the following members: As well as the following members with additional substitutions: 2,5-Dimethoxy-4- ... and 5- positions of the phenyl ring, and a substituent such as alkyl or halogen at the 4- position of the phenyl ring. ...
6-dimethoxy positional isomer of DOM, known as Ψ-DOM, is also mentioned in PiHKAL as being active, as is the alpha-ethyl ... 2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a ... Both the 2- and 5- O-desmethyl derivatives 2-DM-DOM and 5-DM-DOM, and the 2- and 5- ethyl analogues 2-Et-DOM and 5-Et-DOM have ... DOM is a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. Its psychedelic effects are mediated by its agonistic ...
3-dimethoxy-4,5-methylenedioxyamphetamine) TeMA (2,3,4,5-tetramethoxyamphetamine) Not all of these chemicals are bioassayed in ... Many countries have banned the major substances for which this book gives directions for synthesis, such as 2C-B, 2C-T-2, and ... 2C-B (2,5-dimethoxy-4-bromophenethylamine) 2C-E (2,5-dimethoxy-4-ethylphenethylamine) 2C-T-2 (2,5-dimethoxy-4- ... They are found within the first book of PIHKAL, and are as follows: Mescaline (3,4,5-trimethoxyphenethylamine) DOM (2,5- ...
6-dimethoxy-4-methylamphetamine, is a hallucinogenic, psychedelic drug and a structural isomer of the better-known hallucinogen ... The 2,6 isomer of another similar drug 2C-D-FLY (see 2C-B-FLY) has also been made by David E. Nichols and found to be active, ... Indeed any of the 2Cx or DOx series of drugs could alternatively be made as the 2,6 isomer and would still be expected to show ... Translocation of the 5-Alkoxy Substituent of 2,5-Dialkoxyarylalkylamines to the 6-Position: Effects on 5-HT2A/2C Receptor ...
Fenethylline Glutethimide Lefetamine Mecloqualone Methaqualone Methylamphetamine Methylphenidate Nalbuphine Nicocodine ... 2) Regulations 2009 (SI 122/2009) and Misuse of Drugs (Amendment) (No. 2) Regulations 2010 (SI 200/2010). The substances (and ... Schedule 8 (inserted by the 2007 Regulations) lists the drugs that can be prescribed by a registered nurse within schedules 2 ... 1-(1,3-Benzodioxol-5-yl)-2-(1-pyrrolidinyl)-pentanone (i.e. MDPV, added by 2010 Regulations) 1-Benzylpiperazine (added by 2010 ...
The new article 2 in paragraph 9 asks Parties "to use their best endeavours" to apply "such measures of supervision as may be ... Article 2, Paragraph 4: If the World Health Organization finds: (a) That the substance has the capacity to produce (i) (1) A ... The U.S. Controlled Substances Act's 21 U.S.C. § 811(d)(4) implies that placing a drug in Schedule IV or V of the Act is ... Article 2 sets out a process for adding additional drugs to the Schedules. First, the World Health Organization (WHO) must find ...
Methamphetamine (N-methylamphetamine) -CH3. -CH3. Ephedrine pseudoephedrine -CH3. -CH3. -OH ... 3,4,5-TMA (3,4,5-trimethoxyamphetamine, α-methylmescaline) -CH3. -O-CH3. -O-CH3. -O-CH3. ... MDEA (3,4-methylenedioxy-N-ethylamphetamine) -CH2-CH3. -CH3. -O-CH2-O- ... DOM (2,5-dimethoxy-4-methylamphetamine) -CH3. -O-CH3. -CH3. -O-CH3. ...
... , or 2,5-dimethoxy-N-methylamphetamine, is a lesser-known psychedelic drug. Methyl-DMA was first synthesized by ... InChI=1S/C12H19NO2/c1-9(13-2)7-10-8-11(14-3)5-6-12(10)15-4/h5-6,8-9,13H,7H2,1-4H3 Y ... InChI=1/C12H19NO2/c1-9(13-2)7-10-8-11(14-3)5-6-12(10)15-4/h5-6,8-9,13H,7H2,1-4H3 ...
N-methylamphetamine 派醋甲酯(Methylphenidate). N,α-butylene-β-methoxycarbonylphenethylamine ... 苯乙胺(英語:phenethylamine或PEA),或称β-苯乙胺、2-苯乙胺,是一種生物鹼與單胺類神經遞質。苯乙胺有一個结构异构体,即α-苯乙胺或称1-苯乙胺,α-苯乙胺有兩個立體異構體:(R)-(+)-1-苯乙胺與(S)-(-)-1-苯乙胺。在人腦 ... O-CH2-O-. CH3. 3,4-methylenedioxy-N-methylamphetamine 亞甲二氧甲基
Primarily: MAO-B[3][4][5]. Other enzymes: MAO-A,[5][6] SSAOs (AOC2 & AOC3),[5][7] PNMT,[3][4][5] AANAT,[5] FMO3,[8][9] and ... Primarily: MAO-B[3][4][5]. Other enzymes: MAO-A,[5][6] SSAOs (AOC2 & AOC3),[5][7] PNMT,[3][4][5] AANAT,[5] FMO3,[8][9] and ... doi:10.1016/0031-9422(77)83004-5.. *^ a b c d e Irsfeld M, Spadafore M, Prüß BM; Spadafore; Prüß (September 2013). "β- ... 9 (2): 203-206. doi:10.1021/ol062610v. PMC 2593899. PMID 17217265.. *^ a b c Scassellati C, Bonvicini C, Faraone SV, Gennarelli ...
2β-Propanoyl-3β-(4-tolyl)-tropane (WF-11) • 2β-Propanoyl-3β-(2-naphthyl)-tropane (WF-23) • 2-Propanoyl-3-(4-isopropylphenyl)- ... 2β-(3'-phenylisoxazol-5'-yl)nortropane (FE-β-CPPIT) • N-(3'-Fluoropropyl-)-3β-(4'-chlorophenyl)-2β-(3'-phenylisoxazol-5'-yl) ... 2-OH-NPA • A-86,929 • Ciladopa • Dihydrexidine • Dinapsoline • Dinoxyline • Doxanthrine Others: A-68,930 • A-77,636 • A-412,997 ... 2-Amino-1,2-dihydronaphthalene (2-ADN) • 2-Aminoindane (2-AI) • 2-Aminotetralin (2-AT) • 4-Benzylpiperidine (4-BP) • 5-Iodo-2- ...
Dimethoxy-α-PHP, 3,4-DMPHP 4'-Fluoro-α-pyrrolidinohexiophenone, 4-Fluoro-α-PHP 4'-Methyl-α-pyrrolidinohexiophenone, MPHP, 4-Me- ... 3-Fluoromethamphetamine 3-Methylamphetamine, 3-MA, meta-Methamphetamine β-Phenylmethamphetamine N,alpha-Diethylphenylethylamine ... Dimethoxy-α-pyrrolidinopentiophenone, 3,4-DMPV 3',4'-Dimethyl-α-pyrrolidinopentiophenone, 3,4-DMPV 4'-Bromo-α- ... and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products". Forensic Toxicology. 33 (2): 244-259. doi: ...
5-chloro-1-(1-[3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl]piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one ... "British medical journal 2 (6199): 1188. பப்மெட்:519355. *↑ Shindler JS, Finnerty GT, Towlson K, Dolan AL, Davies CL, Parkes JD ... DOM-USA-5 Study Group". Clinical therapeutics 20 (3): 438-53. doi:10.1016/S0149-2918(98)80054-4. பப்மெட்:9663360. ... 5-HT3 Antagonists. Alosetron • Azasetron • Bemesetron • Cilansetron • Clozapine • Dazopride • Dolasetron • Granisetron • ...
6-dimethoxy positional isomer of DOM, known as Ψ-DOM, is also mentioned in PiHKAL as being active, as is the alpha-ethyl ... Both the 2- and 5- O-desmethyl derivatives 2-DM-DOM and 5-DM-DOM, and the 2- and 5- ethyl analogues 2-Et-DOM and 5-Et-DOM have ... 2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a ... DOM is a chiral molecule, and R-(−)-DOM is the more active enantiomer, functioning as a potent agonist of the serotonin 5-HT ...
6-dimethoxy positional isomer of DOM, known as Ψ-DOM, is also mentioned in PiHKAL as being active, as is the alpha-ethyl ... 2,5-Dimethoxy-4-methylamphetamine (DOM; known on the street as STP, standing for "Serenity, Tranquility and Peace") is a ... Both the 2- and 5- O-desmethyl derivatives 2-DM-DOM and 5-DM-DOM, and the 2- and 5- ethyl analogues 2-Et-DOM and 5-Et-DOM have ... DOM is a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. Its psychedelic effects are mediated by its agonistic ...
42 (4): 223-4. doi:10.1016/S1355-0306(02)71832-7. PMID 12632938. de Boer D, Bosman I (2004). "A new trend in drugs-of-abuse; ... 43 (5): 1615-21. doi:10.1016/j.jpba.2006.11.037. PMID 17207601. Venhuis BJ, Blok-Tip L, de Kaste D (2008). "Designer drugs in ... Some compounds such as 2C-B and 5-Meo-DiPT did eventually increase in popularity to the point that they were sold in pill form ... 5 November 2009. "2009 Annual report: the state of the drugs problem in Europe" (PDF). Lisbon: European Monitoring Centre for ...
2,5-Dimethoxy-4-Methyl-Amphetamine: New Hallucinogenic Drug. By Patrick A. Cabe, Solomon H. Snyder, Louis Faillace, Leo ... Sulfur-Containing Nucleoside from Yeast Transfer Ribonucleic Acid: 2-Thio-5(or 6)-uridine Acetic Acid Methyl Ester ...
2,5-Dimethoxy-4-methylamphetamine, a psychedelic drug also known as DOM or STP ... STP, a slang name for the psychedelic 2,5-Dimethoxy-4-methylamphetamine ...
2016 Chapter 2 D. CHAPTER TWO - OFFENSE CONDUCT. PART D - OFFENSES INVOLVING DRUGS AND NARCO-TERRORISM. Historical Note: ... 5). • At least 1 KG but less than 3 KG of Heroin;. • At least 5 KG but less than 15 KG of Cocaine;. • At least 280 G but less ... At least 4 G but less than 7 G of LSD;. • At least 160 G but less than 280 G of Fentanyl;. • At least 40 G but less than 70 G ... at least 4 G but less than 5 G of "Ice";. • At least 40 G but less than 50 G of Amphetamine, or. at least 4 G but less than 5 G ...
2) A substance is a controlled drug if the substance (the drug analogue ) is, in relation to a controlled drug listed in ... 2) A substance is also a border controlled drug if the substance (the drug analogue ) is, in relation to a border controlled ... 2) A substance is a controlled precursor if the substance is a salt or ester of a precursor listed in the table in subsection ( ... 2) A substance is a border controlled precursor if the substance is a salt or ester of a precursor listed in the table in ...
4)‎ . . Night of Champions (2010) ‎ (→‎Results) *12:39, 10 December 2010 (diff , hist) . . (0)‎ . . Dalek ‎ (→‎Movement: (minor ... 2)‎ . . Shao Kahn ‎ (→‎Origins) *12:41, 14 November 2010 (diff , hist) . . (0)‎ . . Scouting in Alabama ‎ (→‎Black Warrior ... 2)‎ . . Grit (newspaper) ‎ (→‎Comic strips: minor spelling correction) *15:43, 14 June 2010 (diff , hist) . . (-5)‎ . . Matt ... 12:16, 2 June 2010 (diff , hist) . . (+10)‎ . . Washington Naval Treaty ‎ (→‎Terms: grammar...missing word in the sentence) ...
5-MeO-AMT. Dimethyltryptamine. Phenethylamine. 2C-B-FLY. Mescaline. 2C-D. 2C-C. 2C-T-2. 2C-T-7. 2C-T-4. 2C-B. 2C-E. 2C-T-21. 2, ... 2-MDP. 2-MDP (U-23807A) is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar ... The levo or (-) isomer is the active form of the drug.[1][2] It also has stimulant effects, having only around one third the ... Ibotenic acid is a powerful neurotoxin that is used as a brain-lesioning agent[1][2] and has shown to be highly neurotoxic ...
4 Effects of a range of doses of 8-OH-DPAT alone and in combination with WAY-100,635 (0.3 mg/kg, SC) in rats trained with LSD ( ... Figure 4 illustrates the use of M100907 and WAY-100,635 to rationalize the effects of 8-OH-DPAT in rats trained with LSD as a ... 5-methoxy-N,N-dimethyltrypamine Against the background provided above implicating the 5-HT2A receptor as the primary site of ... 2000) and that the 5-HT2C receptor may play a significant role (Eckler et al. 2004; Winter et al. 2005b). Direct testing of the ...
Figure 4. All of the cell bodies of neurons containing serotonin are found in the brainstem, a primitive part of the brain that ... Figure 5. The picture of chemical neurotransmission shown in Figure 3 is complicated by the fact that the receptors in ... Figure 2. Although hallucinogenic drugs are grouped together by their tendency to elicit common psychic, somatic, and sensory- ... 2): LSD is an ergot derivative; mescaline and DOM are phenylethylamines; and Psilocin and DMT are indoleamines. However, as we ...
Case 4*Allen v. Purdue Pharma L.P. (Stamford, CT 2002) *Plaintiff alleges that Mrs. Allen took OxyContin and, as a direct and ... 5. Controlled Substances Act (CSA) *Enacted into law by the Congress of the United States as Title II of the Comprehensive Drug ... Case 2*Jenks v. State, Fla. Dist1991Summary Jenks and his wife, who both suffered from AIDS, were convicted of manufacturing ... Case 5*Doctor Guilty in OxyContin case (FL, 2002) *Dr. James Graves ,Floridas top OxyContin prescriber, was convicted of ...
See §1B1.3(a)(2) (Relevant Conduct). Where there is no drug seizure or the amount seized does not reflect the scale of the ...
Adult male rats were trained to discriminate DiPT (5 mg/kg, 15 min) from saline under a FR10 schedule. A dose-effect and time ... Rats learned to discriminate DiPT from saline in an average of 60 training sessions (30 drug and 30 saline). DiPT (0.5-5 mg/kg ... Titeler M, Lyon RA, Glennon RA (1988) Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for ... Shulgin AT, Carter MF (1980) N, N-Diisopropyltryptamine (DIPT) and 5-methoxy-N, N-diisopropyltryptamine (5-MeO-DIPT). Two ...
Looking for online definition of -dom in the Medical Dictionary? -dom explanation free. What is -dom? Meaning of -dom medical term. What does -dom mean?
Next Document: Antagonism of the behavioral effects of 2,5-dimethoxy-4-methylamphetamine (DOM) and quipazine by met.... ...
2) the possible hallucinogens involved in HPPD induction; (3) the clinical features of both HPPD I and II; (4) the possible ... psychiatric comorbidities; and (5) the available and potential therapeutic strategies. We searched PubMed to identify original ... N-methylamphetamine; LSD: lysergic acid diethylamide; JWH-122: 4-methyl-1-(naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone. ... Perphenazine (4-8 mg/day) [17,23], Sulpiride (50-100 mg/day) [23], and Zuclopenthixol (2-10 mg/day) [17,23], at very low doses ...
Planning My Day (5-Minute Meditation Video) Planning My Day (Picture) Reviewing My Day Or Week (5-Minute Meditation Video) Life ... BEING CLOSED TO EXPERIENCE" modified from "PID-5" by Kreuger RF, Derringer J, Markon KE, Watson D, Skodol AE and Between facets ... Antagonism" modified from "PID-5" by Kreuger RF, Derringer J, Markon KE, Watson D, Skodol AE and Between facets and domains: 10 ... Detachment" modified from "PID-5" by Kreuger RF, Derringer J, Markon KE, Watson D, Skodol AE and Between facets and domains: 10 ...
2 0.05 EPZ-5676 supplier and ** 0.01 vs. C; + 0.05 and ++ 0.01 vs. H2O2.; = 6C8 per group. Thus our data claim that metformin ... 4, and 0.01 vs. C; + 0.01 vs. H2O2; # 0.01 vs. Met; = 3 per each group. These data demonstrate that AMPK activation decreases ... For cutoff 5 and 5.75% genotypic testing using proviral DNA showed an identical sensitivity for X4 as RNA. We discovered that ... 2 0.01) at 300 M H2O2. Treatment of control cells with metformin alone exerted the utmost influence on AMPK phosphorylation at ...
It is unknown how many items of mail containing illegal drugs slipped through to Barker and Smiths homes, but on June 2, 2016 ... Inside the teenagers bedroom officers found lysergic acid and a drug known by its street name "DOM" (2,5-Dimethoxy-4- ... methylamphetamine). That same day police banged on Smiths front door - he wasnt home, but his parents were. ...
5-MeO-DMT) and its salts into schedule I of the Controlled Substances Act (CSA). This proposed action is based on a... ... is issuing this notice of proposed rulemaking to place the substance 5-methoxy-N,N-dimethyltryptamine ( ... Placement of 5-MeO-DMT Into Schedule I In accordance with 21 U.S.C. 811(b) of the CSA, DEA has gathered and reviewed the ... 1) 5-MeO-DMT has a high potential for abuse. (2)5-MeO-DMT has no currently accepted medical use in treatment in the United ...
2,5-dimethoxy-4-methylamphetamine (STP) and other powerful synthetic psychoactive drugs in the 1960s. In the early 1950s, the ...
2 In the form of leaf powder or tea, coca is taken for toothache, ulcers, rheumatism, asthma, and even malaria. Coca tea is ... 4 (1967): 11-13; H. B. M. Murphy, 0. Rios, and J. C. Negrete, The Effects of Abstinence and Retraining on the Chewer of Coca ... 4. Carlos Gutierrez-Noriega, El Cocaismo y la Alimentacion en el Peru, Anales de la Facultad de Medicina 31 (1948): 1-90; J. ... 5. Lester Grinspoon and James B. Bakalar, Cocaine: A Drug and Its Social Evolution (New York: Basic Books, 1976), pp. 120-29; ...
2. Disposal of stocks. Any person who does not desire or is not able to obtain a schedule I registration would be required to ... 4\ While law enforcement data is not direct evidence of abuse, it can lead to an inference that a drug has been diverted and ... 4. Its History and Current Pattern of Abuse: Abuse of PMMA was first documented in the late 1980s and associated with ecstasy ... 5. The Scope, Duration, and Significance of Abuse: PMMA abuse has been associated with ecstasy tablets and is used as a ...
5-dimethoxy-4- (n)-propylthiophenethylamine (2C-T-7), N-Benzylpiperazine (BZP), and 1- (3-trifluoromethylphenyl)piperazine ( ... is issuing this notice of proposed rulemaking to place 2, ... 2. Section 1308.11 is proposed to be amended by: a. ... 52872-52875 (4 pages) CFR:. 21 CFR 1308. Agency/Docket Number:. Docket No. DEA-247P. Document Number:. 03-22684. ... The CSA (21 U.S.C. 811(h)(2)) requires that the temporary scheduling of a substance expire at the end of one year from the date ...
  • 2. any of a group of drugs closely related to this substance and having similar actions, such as methamphetamine and dextroamphetamine . (thefreedictionary.com)
  • In the present study, we investigated 5-HT involvement in the discriminative stimulus effects of methamphetamine. (aspetjournals.org)
  • In Sprague-Dawley rats trained to discriminate 1.0 mg/kg methamphetamine i.p. from saline under a fixed-ratio schedule of food presentation, the effects of selected 5-HT agonists, antagonists, and uptake inhibitors were tested. (aspetjournals.org)
  • Both 8-hydroxy-2-dipropylaminotetralin (0.03-0.56 mg/kg), a full agonist, and buspirone (1.0-10.0 mg/kg), a partial agonist at 5-HT 1A receptors, partially generalized to the training dose of methamphetamine but only at high doses that decreased response rate. (aspetjournals.org)
  • 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (0.3 mg/kg), a 5-HT 2A/2C agonist, shifted the methamphetamine dose-response curve to the left, and this leftward shift was antagonized by the coadministration of ketanserin (3.0 mg/kg), a 5-HT 2A/2C antagonist. (aspetjournals.org)
  • In contrast, tropisetron (1.0 mg/kg), a 5-HT 3 antagonist, produced a shift to the left of the methamphetamine dose-response curve, and this effect of tropisetron was antagonized by the coadministration of m -chlorophenyl-biguanide (1.8 mg/kg), a 5-HT 3 agonist. (aspetjournals.org)
  • The present data suggest that the 5-HT system plays a modulatory role in the discriminative stimulus effects of methamphetamine. (aspetjournals.org)
  • [ 2 ] This suggests that while α-Et-DOM may lack hallucinogenic effects, it might potentially produce empathogenic effects similar to those of MDMA if used at higher dose ranges, beyond those trialled by Shulgin (the potency of α-Et-DOM in this study was similar to that of MDMA, 1.5 mg/kg, which would equate to a dose of ~100 mg in a human). (worldlibrary.net)
  • La MDMA ("ekstazo") sintezo publikigita en PIHKAL restas unu el la plej oftaj sekretaj metodoj de it fabrikado al tiu tago. (wikitrans.net)
  • MDMA (3, 4-methylenedioxymethampheta-mine) is a complex drug that makes simple classification difficult. (ecstasy.com.ua)
  • 2-CB is distantly related to MDMA ( ecstasy ). (ecstasy.com.ua)
  • [ 5 ] The term gained widespread popularity when MDMA (ecstasy) experienced a popularity boom in the mid 1980s. (naturalhighdruginfomation.co.uk)
  • but most individuals report the duration of the drug's effects to be around 5-6 hours, slightly longer than that of MDMA. (thefullwiki.org)
  • Other precursor analogs chemically related to PCP include N-ethyl-1 phenylcyclohexylamine (PCE), 1-(1-phenyl-cyclohexyl)-pyrrolidine (PCP or PHP), and 1-(1-(2 thienyl-cyclohexyl)-piperdine (TPCP or TCP). (ecstasy.com.ua)
  • 3,4-Methylenedioxyamphetamine (MDA) in particular is a receptive parent compound for the molecular modifications which produce such homologs and analogs. (designer-drug.com)
  • Titeler, M. 5-HT 1 and 5-HT 2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogs . (isomerdesign.com)
  • Analogues where the methoxy groups at the 2,5- positions of the aromatic ring have been altered have also been synthesised and tested as part of an effort to identify the binding mode of DOM at the 5-HT2A receptor. (wikipedia.org)
  • Both the 2- and 5- O-desmethyl derivatives 2-DM-DOM and 5-DM-DOM, and the 2- and 5- ethyl analogues 2-Et-DOM and 5-Et-DOM have been tested, but in all cases were significantly less potent than the corresponding methoxy compound, showing the importance of the oxygen lone pairs in 5-HT2A binding. (wikipedia.org)
  • The 2,6-dimethoxy positional isomer of DOM, known as Ψ-DOM, is also mentioned in PiHKAL as being active, as is the alpha-ethyl homologue Ariadne. (wikipedia.org)
  • [2] الباقي يتم تخليقه في العصبونات serotonergic في الجهاز العصبي المركزي حيث لها عدة وظائف، منها تنظيم المزاج والشهية والنوم وانقباض العضلات وبعض الوظائف التعارفية التي منها الذاكرة والتعلم. (marefa.org)
  • The Deputy Administrator of the Drug Enforcement Administration (DEA) is issuing this notice of proposed rulemaking to place the substance 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and its salts into schedule I of the Controlled Substances Act (CSA). (federalregister.gov)
  • For the purpose of establishing criminal penalties for violations of this chapter, controlled substances, including a material, compound, mixture, or preparation containing the controlled substance, are divided into Penalty Groups 1 through 4. (public.law)
  • The technique of selected ion monitoring 1 , which was originally given the name mass fragmentography 2 , has proven extremely useful in recent years for the quantification of organic compounds at low levels. (thevespiary.org)
  • As a recreational drug, 4-FA is sometimes sold along with related compounds such as 2-fluoroamphetamine and 4-fluoromethamphetamine. (chemchart.com)
  • Major metabolites are 3,4-methylenedioxyamphetamine (MDA) and O-demethylated compounds. (researchchemicalblog.com)
  • Pihkal: Chemical Love Story estas libro de Dr. Alexander Shulgin kaj Ann Shulgin kiu estis publikigita en 1991. (wikitrans.net)
  • harmine (found in a South American vine)   and 5-MeO-DMT and bufotenine (which naturally occurs in the venom of certain toads). (verywellmind.com)
  • The residue was dissolved in chloroform and washed with aqueous 5% NaOH solution, then with water. (erowid.org)
  • The pooled extracts were washed with 2x150 mL 5% NaOH and once with dilute HCl, and the solvent was removed under vacuum to give 19.0 g of a black oil as a residue. (textfiles.com)
  • The combined organic fractions were washed with 5% NaOH, and the solvent removed under vacuum. (textfiles.com)
  • After a few min further stirring, the temperature was brought up to a gentle reflux on the steam bath for 10 min, and then all was cooled again to 0 !C. The excess hydride was destroyed by the cautious addition of 7 mL IPA, followed by 2 mL 15% NaOH and 5 mL H2O, which gave an easily filtered white granular solid. (textfiles.com)
  • There exist six different TMAs that differ only in the position of the three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. (chemchart.com)
  • [ citaĵo bezonis ] En 1994, du jarojn post kiam PIHKAL estis publikigita, la Drug Enforcement Administration (DEA) trudeniris la laboratorion de Shulgin kaj petis ke li turno super lia DEA licenco. (wikitrans.net)
  • It has also been shown that in drug naive Schizophrenic patients (patients who have never been medicated for Schizophrenia), there is an increase in dopamine synthesis and presynaptic storage in the striatal region of the brain [ 5 ]. (wikidot.com)
  • Casley, W. Metabolism of methoxyphenamine and 2-methoxyamphetamine in P4502D6-transfected cells and cell preparations . (isomerdesign.com)
  • OBJECTIVE: This study examined the effects of several inhibitors of Ca(2+) signaling mechanisms on two behavioral effects of the prototypical imidazoline I2 receptor ligand 2-(2-benzofuranyl)-2-imidazoline (2-BFI). (rti.org)
  • Ibotenic acid is a powerful neurotoxin that is used as a 'brain-lesioning agent'[2] and has shown to be highly neurotoxic when injected directly into the brains of mice and rats. (pearltrees.com)
  • A sensitive method for determining levels of [-]-2,5,-dimethoxy-4-methylamphetamine in the brain tissue. (naver.com)
  • Comparative Biochemistry and Physiology - C Toxicology and Pharmacology , 158 (4), 207-215. (elsevier.com)
  • NetCE designates this continuing education activity for 2 pharmacotherapeutic/pharmacology contact hour(s). (netce.com)
  • 2] Ibotenic acid. (pearltrees.com)
  • Inside the teenager's bedroom officers found lysergic acid and a drug known by its street name "DOM" (2,5-Dimethoxy-4-methylamphetamine). (dailymercury.com.au)
  • We therefore employed three previously characterized, chemically-distinct natural DOMs, as well as a commercially available humic acid (Aldrich, AHA), at circumneutral (7-8) and acidic pH (~ 5), to examine DOM effects on whole-body Na + concentration, unidirectional influx and efflux rates of Na + , and ammonia and urea excretion rates in Daphnia magna. (elsevier.com)
  • METHODS: The von Frey filament test was used to examine the antinociceptive effects of 2-BFI in complete Freund's adjuvant (CFA)-induced inflammatory pain in rats. (rti.org)
  • Introduction: The aim of this investigation was to evaluate methods for increasing Caco-2 cell throughput for assessing drug intestinal absorption. (naver.com)
  • A reasonable compromise was to prepare standards with at least 4 deuterium atoms per molecule but with as few in excess of 4 as was convenient from a synthesis standpoint. (thevespiary.org)
  • 2) is there a suitable method of synthesis? (designer-drug.com)
  • 3,6-DIMETHOXY-4-(2-AMINOETHYL)BENZONORBORNANE SYNTHESIS: To a stirred solution of 25 g 3,6-dihydroxybenzonorbornane (from Eastman Kodak Company) in 200 mL acetone there was added 200 mg decyltriethylammonium iodide, 40 g of powdered anhydrous K2CO3, and 55 g methyl iodide. (textfiles.com)
  • 6. The example of the anticancer drugs tamoxifen and 4-hydroxytamoxifen shows that merely the absence or presence of certain substituents can change the distribu- Page Yьu п4. (thesiri.ru)
  • Influence of amine substituents on 5-HT 2A versus 5-HT 2C binding of phenylalkyl- and indolylalkylamines. (isomerdesign.com)
  • La ĉi-suba teksto estas aŭtomata traduko de la artikolo PiHKAL article en la angla Vikipedio , farita per la sistemo GramTrans on 2016-06-06 08:40:17. (wikitrans.net)
  • Richard Meyer, reprezentanto por San Francisco Field Division de DEA, deklaris en referenco al PIHKAL "estas nia opinio-tio those libroj-aro bela multaj kuirlibroj sur kiel fari kontraŭleĝajn medikamentojn. (wikitrans.net)
  • Agentoj rakontas al mi tion en sekretaj laboratorioj kiujn ili trudeniris, ili trovis kopiojn de tiuj libroj", sugestante ke la publikigo de PIHKAL kaj la fino de la licenco de Shulgin eble estis ligitaj. (wikitrans.net)
  • Ne ĉiuj tiuj kemiaĵoj estas bioasaieitaj en PIHKAL , kelkaj estas simple menciis. (wikitrans.net)
  • Although Sasha later wrote that his doctoral work was "uninspired" and "dull" (PiHKAL, Chapter 2), adjectives like these are commonly applied to graduate-school projects. (psychedelicfrontier.com)
  • Mexedrone (3-methoxy-2-(methylamino)-1-(p-tolyl)propan-1-one also known as 4-MMC-MeO) is a putative stimulant and possible euphoriant of the cathinone chemical class with a potency of roughly 1/10th of that of mephedrone. (bremer-bau-kontor.de)
  • A mistaken for 2,5-dimethoxy-4-methylamphetamine, one after repair injury during child or pulmonary embolism is more common chemical viagra generic online usa such signs and small bowel, bladder, and 21 47), although this technique of interpreting the diagnosis of cotrimoxozole. (rainierfruit.com)
  • The full chemical name: 2,5 dimethoxy 4 nitro benzeneethanamine. (exchems.com)
  • The full chemical name is 25I-NBOMe: 4-iodo-2,5-dimethoxy-N - [(2-methoxyphenyl) methyl] -benzeneethanamine, monohydrochloride. (exchems.com)