A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
Organic compounds that contain two nitro groups attached to a phenol.
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.
Iodinated derivatives of acetic acid. Iodoacetates are commonly used as alkylating sulfhydryl reagents and enzyme inhibitors in biochemical research.
Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.
Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033)
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy.
Organic or inorganic compounds that contain the -N3 group.
Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
Chloride and mercury-containing derivatives of benzoic acid.
An antibiotic substance produced by Streptomyces species. It inhibits mitochondrial respiration and may deplete cellular levels of ATP. Antimycin A1 has been used as a fungicide, insecticide, and miticide. (From Merck Index, 12th ed)
A highly poisonous compound that is an inhibitor of many metabolic processes, but has been shown to be an especially potent inhibitor of heme enzymes and hemeproteins. It is used in many industrial processes.
An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases.
An ionic monomeric contrast medium that was formerly used for a variety of diagnostic procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed)
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Derivatives of SUCCINIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,4-carboxy terminated aliphatic structure.
Derivatives of acetic acid with one or more fluorines attached. They are almost odorless, difficult to detect chemically, and very stable. The acid itself, as well as the derivatives that are broken down in the body to the acid, are highly toxic substances, behaving as convulsant poisons with a delayed action. (From Miall's Dictionary of Chemistry, 5th ed)
The study of the origin, nature, properties, and actions of drugs and their effects on living organisms.
Inorganic or organic salts and esters of arsenic acid.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
The chemical reactions that occur within the cells, tissues, or an organism. These processes include both the biosynthesis (ANABOLISM) and the breakdown (CATABOLISM) of organic materials utilized by the living organism.
A class of carbohydrates that contains five carbon atoms.
Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.
The rate dynamics in chemical or physical systems.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A botanical insecticide that is an inhibitor of mitochondrial electron transport.
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.
The complete absence, or (loosely) the paucity, of gaseous or dissolved elemental oxygen in a given place or environment. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
A sulfhydryl reagent that is widely used in experimental biochemical studies.
A highly poisonous compound that is an inhibitor of many metabolic processes and is used as a test reagent for the function of chemoreceptors. It is also used in many industrial processes.
A group of glycine amides of aminobenzoic acids.
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
A bacterial genus of the order ACTINOMYCETALES.
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
A ketotriose compound. Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
Life or metabolic reactions occurring in an environment containing oxygen.
Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.
Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.
The chemical reactions involved in the production and utilization of various forms of energy in cells.
Inorganic salts of phosphoric acid.
Irritants and reagents for labeling terminal amino acid groups.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
A proton ionophore that is commonly used as an uncoupling agent in biochemical studies.
A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.
A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
6-dinitrophenol, is an acid obtained by neutralizing an alcoholic solution of picric acid with ammonium hydroxide. Hydrogen ... 6-dinitrophenol". pubchem.ncbi.nlm.nih.gov. Retrieved 27 December 2021. "Haz-Map Category Details". Archived from the original ... 6-DINITROPHENOL)". Archived from the original on 2011-08-29. Retrieved 2011-04-30. "Final Report on the Safety Assessment of ... 11 (4): 447-464. July 1992. doi:10.3109/10915819209141884. S2CID 208504486. (CS1 maint: archived copy as title, Articles ...
2,4-Dinitrophenol for human use. Disperse Yellow 3 for use in hair dyes. Dulcin for therapeutic use. Ethylene glycol for use in ... cost of the drug is high, or when there is a risk of dependence The price of many Schedule 4 substances are subsidized by the ... Schedule 2 (S2) drugs and poisons, otherwise known as Pharmacy Medicines, are substances and preparations for therapeutic use ... Basic Orange 31 (2-[(4-aminophenyl)azo]-1,3-dimethyl-1H-imidazolium chloride) in preparations for skin colouration and dyeing ...
Parascandola J (November 1974). "Dinitrophenol and bioenergetics: an historical perspective". Molecular and Cellular ... use of the then much vaunted weight loss medication dinitrophenol, which his report found killed as many patients as it reduced ... he warned against the use of dinitrophenol as an anti-obesity medication and the injudicious and/or medically unsupervised use ... Retrieved 2 November 2016. Wilding JP, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al. (March 2021). "Once- ...
Fisheries 29(2): 22-33. Niyogi S, and Wood CM. 2004. Biotic Ligand Model, a flexible tool for developing site-specific water ... Available online at: Stormwater and Salmon- Pre-spawn Mortality of Coho Salmon in Restored Urban Streams Accessed on 4 May 2013 ... 4-dinitrophenol, tricaine methanesulfonate and 1-octanol. Environmental Toxicology and Chemistry 6: 295-312. Laetz CA, Baldwin ...
I. Purification and properties of soluble dinitrophenol-stimulated adenosine triphosphatase". J. Biol. Chem. 235 (11): 3322-9. ... The transport of electrons from redox pair NAD+/ NADH to the final redox pair 1/2 O2/ H2O can be summarized as 1/2 O2 + NADH + ... 5 (2): 107-18. doi:10.2174/1389203043486847. PMID 15078221. Kita K, Hirawake H, Miyadera H, Amino H, Takeo S (2002). "Role of ... 54 (4): 259-70. doi:10.1111/j.1574-6968.1988.tb02746.x. PMID 2856189. Iuchi S, Lin EC (1993). "Adaptation of Escherichia coli ...
6 (4): 295-312. doi:10.1002/etc.5620060407. Russom CL, Bradbury SP, Broderius SJ, Hammermeister DE, Drummond RA (1997). " ... 2,4-dinitrophenol, tricaine methanesulfonate and 1-octanol". Environmental Toxicology and Chemistry. ...
4 (2): e4377. Bibcode:2009PLoSO...4.4377R. doi:10.1371/journal.pone.0004377. PMC 2634841. PMID 19198647. "Nutrition for Injury ... Lu, Yuan-qiang; Jiang, Jiu-kun; Huang, Wei-dong (March 2011). "Clinical features and treatment in patients with acute 2,4- ... dinitrophenol poisoning". Journal of Zhejiang University Science B. 12 (3): 189-192. doi:10.1631/jzus.B1000265. ISSN 1673-1581 ...
2,4-Dinitrophenol (m.p. 83 °C) is a moderately strong acid (pKa = 4.89). 2,4,6-Trinitrophenol is better known as picric acid, ... Three isomeric nitrophenols exist: o-Nitrophenol (2-nitrophenol; OH and NO2 groups are neighboring; CAS number: 88-75-5), a ... 4-nitrophenol, CAS number: 100-02-7), yellow crystals (m.p. 114 °C). It is a precursor to the rice herbicide fluorodifen, the ...
244 (4): 621-9. doi:10.1016/S0021-9258(18)94400-5. PMID 4388793. Portal: Biology v t e (CS1 errors: missing periodical, ... 32 (2): 103-110. ISSN 0126-8635. PMID 21329181. Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith ... Several compounds are known to inhibit this enzyme, including AMP, and 2,4-dinitrophenol. NADH dehydrogenase is involved in the ...
doi:10.1007/978-3-319-12415-5_4. PMID 25707467. Campbell, N.A., 2008. Resource Acquisition and Transport in Vascular Plants. ... Active transport Chemiosmosis Cytochrome Protonophore Proton-pump inhibitor Uncoupler 2,4-Dinitrophenol V-ATPase Yoshikawa, ... Section 4 Proton Pump Mechanism". In Peter M.H. Kroneck and Martha E. Sosa Torres (ed.). Sustaining Life on Planet Earth: ... Shinya; Shimada, Atsuhiro; Shinzawa-Itoh, Kyoko (2015). "Chapter 4, ...
The most important member of the class is Sulfur Black 1. It is produced by the reaction of 2,4-dinitrophenol and sodium ... The so-called sulfur bake dyes are produced from 1,4-diaminobenzene and diaminotoluene derivatives. These dyes are proposed to ...
MVax's Phase II response rate of 35% (CR + PR) in combination with low-dose IL-2 compares favorably to the Phase II results of ... 4-Dinitrophenol. When reinjected back into the patient, the hapten will cause an enhanced immune response against the cancer ...
In metallurgy, a 4% picric acid in ethanol etch termed "picral" has been commonly used in optical metallography to reveal prior ... 3rd series (in French). 2: 204-232. From p. 228: "C'est sous ce nom que j'ai désigné l'acide carboazotique, ..." (It is by this ... Its IUPAC name is 2,4,6-trinitrophenol (TNP). The name "picric" comes from Greek: πικρός (pikros), meaning "bitter", due to its ... Archived 2019-04-30 at the Wayback Machine pdf, Pg.33 2"Measuring blood glucose levels in the 1920s". Tacomed.com. Archived ...
4-dinitrophenol". Journal of Biological Chemistry. 255 (3): 1054-1057. ISSN 0021-9258. PMID 7356650. Wikidata Q54557561. {Cite ... cyanide-resistant superoxide dismutase in the livers of rats treated with 2, ...
On the internet, dinoseb and other dinitrophenols are bought as weight-loss pills. It is very dangerous however, and many ... Zaharia, M.; Tudorachi, L.; Pintilie, O.; Drochioi, C.; Gradinaru, R.; Murariu, M. (2016). "Banned dinitrophenols still trigger ... a herbicide in the dinitrophenol family. It is a crystalline orange solid which does not readily dissolve in water. Dinoseb is ... For small fish like goldfish only 0,4 ppm is needed to kill all fish in the water. When a fish lives in an acidic water ...
Figure 2 shows the different types of results generated. Advantages No PCR is required, which means that there will be no ... Figure 2). The raw data are analyzed by the proprietary software, and the fluorescence intensity ratios between the two bead ... 2] Annotation for Illumina's 450k methylation arrays, on Bioconductor Epigenetics Methylation Station Nature Reviews:DNA ... The ddCTP and ddGTP are labeled with biotin while ddATP and ddUTP are labeled with 2,4-dinitrophenol (DNP). Fluorescence ...
2 (2): 85-93. doi:10.1016/j.cmet.2005.06.002. PMID 16098826. Sreedhar A, Zhao Y (May 2017). "Uncoupling protein 2 and metabolic ... 9 (2): 203-9. doi:10.1016/j.cmet.2008.12.014. PMID 19187776. Andrews ZB, Diano S, Horvath TL (November 2005). "Mitochondrial ... 23 (4): 166-74. doi:10.1016/s0166-2236(99)01534-9. PMID 10717676. S2CID 11564585. (Articles with short description, Short ... Horvath TL, Warden CH, Hajos M, Lombardi A, Goglia F, Diano S (December 1999). "Brain uncoupling protein 2: uncoupled neuronal ...
... crystallises in the monoclinic form. The unit cell has these sizes and angles: a=8.772 Å b=12.645 Å c=15.429 ... 2,4-Dinitroanisole is used as an explosive replacing TNT. It is used in explosive mixtures such as IMX-101, IMX-104, PAX-48, ... 2,4-Dinitroanisole can be formed from p-nitroanisole or o-nitroanisole nitration. Also it can be formed from 1-chloro-2,4- ... The specific heat of solid 2,4-dinitroanisole is given by Cp (Jmol−1K−1) = 0.3153 + 0.00265T (T in K). At 298.15 K. it is ...
2 (1): 45. doi:10.1186/2191-0855-2-45. PMC 3583297. PMID 22909015. Ho MC, Ménétret JF, Tsuruta H, Allen KN (May 21, 2009). "The ... 71 (2): 173-83. doi:10.1016/0009-8981(76)90528-3. PMID 963888. "Human Metabolism" (PDF). Galassetti PR, Novak B, Nemet D, Rose- ... In the presence of acetic anhydride, the enzyme is inactivated, unable to catalyze the hydrolysis reaction 2,4-dinitrophenyl ... propionate to dinitrophenol. Acetonylsulfonate acts as a competitive inhibitor (KI=8.0 mM ) as it mimics the characteristics of ...
The drug 2,4-dinitrophenol, which also acts as a chemical uncoupler similarly to UCP1, was used for weight loss in the 1930s. ... 19 (4): 593-604. doi:10.1016/j.cmet.2014.03.007. PMC 4012340. PMID 24703692. Wang W, Kissig M, Rajakumari S, Huang L, Lim HW, ... 151 (2): 400-413. doi:10.1016/j.cell.2012.09.010. PMC 3782081. PMID 23063128. Azzu V, Brand MD (May 2010). "The on-off switches ... 77 (1-2): 27-35. doi:10.1016/j.steroids.2011.10.013. PMC 3286233. PMID 22108547. Löhn M, Dubrovska G, Lauterbach B, Luft FC, ...
Since 2,4-dinitrophenol is in a lower energy state it will not return to form the reactant, so after some time has passed, the ... A small percentage of the intermediate loses the chloride to become the product (2,4-dinitrophenol), while the rest return to ... In the compound methyl 3-nitropyridine-4-carboxylate, the meta nitro group is actually displaced by fluorine with cesium ... The following is the reaction mechanism of a nucleophilic aromatic substitution of 2,4-dinitrochlorobenzene in a basic solution ...
622 (1-2): 85-95. doi:10.1016/S0166-1280(02)00620-6. McKim JM, Schmieder PK, Carlson RW, Hunt EP (April 1987). "Use of ... 6 (4): 295-312. doi:10.1002/etc.5620060407. McKim JM, Schmieder PK, Niemi GJ, Carlson RW, Henry TR (April 1987). "Use of ... 6 (4): 313-328. doi:10.1002/etc.5620060408. Bradbury SP, Carlson RW, Henry TR (1989). "Polar Narcosis in Aquatic Organisms". In ... 172 (2): 599-608. PMID 18901179. Russom CL, Bradbury SP, Broderius SJ, Hammermeister DE, Drummond RA (May 1997). "Predicting ...
Duchaine is also credited with introducing 2,4-Dinitrophenol (DNP) into bodybuilding through an interview on one of ten ...
269 (1 Pt 2): R38-R47. doi:10.1152/ajpregu.1995.269.1.R38. PMID 7631901. Cao Y, Ohwatari N, Matsumoto T, Kosaka M, Ohtsuru A, ... 37 (1-2): 19-35. PMID 17641392. Archived from the original on 2013-01-28. Mai AS, Dos Santos AB, Beber LC, Basso RD, Sulzbacher ... 354 (1-2): 23-27. doi:10.1016/j.ijpharm.2007.09.030. PMID 17980980. Bendz H, Ruhland SC, Pandya MJ, Hainzl O, Riegelsberger S, ... 16 (2): 123-132. doi:10.1016/j.copbio.2005.02.001. PMID 15831376. Kampinga HH, Hageman J, Vos MJ, Kubota H, Tanguay RM, Bruford ...
1: 2. Tips to Beat the Heat Archived 21 July 2014 at the Wayback Machine-American Red Cross Extreme Heat-CDC Emergency ... 10 (2): 161-167. doi:10.1016/j.als.2016.11.004. ISSN 2078-1520. Wust, P; Hildebrandt, B; Sreenivasa, G; Rau, B; Gellermann, J; ... From this group of drugs the most well-known is 2,4-dinitrophenol which was used as a weight loss drug until dangers from its ... 26 (2): 585-603, xi. doi:10.1016/j.ncl.2008.02.005. PMID 18514828. Thompson, Hilaire J.; Tkacs, Nancy C.; Saatman, Kathryn E.; ...
Also, as dinitrophenol is a metabolic and respiratory stimulant, this morphine derivative was invented in Austria in 1931 as a ... 9 (2): 314-318. PMID 14835466. Reynolds and Randall, "Morphine and Allied Drugs", U of Toronto, 1957 pp 203 et al. v t e ( ... 2,4-Dinitrophenylmorphine is an analog of morphine in which a hydroxyl group is substituted with a dinitro phenoxy group. Being ... 2,4-Dinitrophenylmorphine" (PDF). Journal of Pharmacology and Experimental Therapeutics. 67 (2): 127-141. Huggins, R. A.; Bryan ...
Kumar S, Barker K, Seger D (2002). "Dinitrophenol-Induced Hyperthermia Resolving With Dantrolene Administration. Abstracts of ... Barker K, Seger D, Kumar S (2006). "Comment on "Pediatric fatality following ingestion of Dinitrophenol: postmortem ... 81 (4): 626-9, discussion 625. doi:10.1093/bja/81.4.626. PMID 9924249. Kolb ME, Horne ML, Martz R (April 1982). "Dantrolene in ... 4 May 2020. Retrieved 6 July 2020. Zucchi, R; Ronca-Testoni, S (March 1997). "The sarcoplasmic reticulum Ca2+ channel/ryanodine ...
... can mean: 2,4-Dinitrophenol, a small organic molecule formerly marketed as a pharmaceutical "diet aid" 2,4- ...
The molecular formula C6H4N2O5 may refer to: Dinitrophenols 2,3-Dinitrophenol 2,4-Dinitrophenol 2,5-Dinitrophenol 2,6- ... 5-Dinitrophenol This set index page lists chemical structure articles associated with the same molecular formula. If an ...
... may refer to: 2,4-Dinitrophenol, a small organic molecule formerly marketed as a pharmaceutical "diet aid" ...
"Retrieved 4 October 2008.. *^ Aronne LJ, Tonstad S, Moreno M, Gantz I, Erondu N, Suryawanshi S, Molony C, Sieberts S, Nayee J, ... Others: 2-PG (directly potentiates activity of 2-AG at CB1 receptor) ... N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)-2-butanyl]-2-methyl-2-{[5-(trifluoromethyl)-2-pyridinyl]oxy}propanamide ... Jun 2007). "Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3- ...
In this method, a probe tagged with dinitrophenol (DNP) binds to the target sequence. A primary anti-DNP antibody is then added ... Amplification of HER-2/neu is seen as black dots. DuoCISH is a variation of CISH that addresses the need for two different ... HER-2/neu amplification is associated with higher mortality, higher recurrence rate, and poor prognosis in breast cancer. The ... 87 (2): 117-21. doi:10.3109/10520295.2011.559175. PMID 21314248. De Braekeleer, E; Douet-Guilbert, N; Basinko, A; Morel, F; Le ...
... products containing dinitrophenol, arsenic, and other dangerous substances), cancer "quackery" (alternate cancer therapies), " ... JSTOR j.ctt13x1b4x.4. "Dr. Cramp to Speak Here". Dubuque Telegraph Herald and Times Journal. Dubuque, Iowa. November 12, 1933. ... 2 (4): 285-289. doi:10.2307/1147355. JSTOR 1147355. Cramp, Arthur J. (July 1935). "Salts and Crystals Quackery". Hygeia. 13: ... They had a daughter, Torrey, who died on January 2, 1900. The infant's death was caused by seizures related to meningitis. ...
Dinitrophenols are chemical compounds which are nitro derivatives of phenol. There are six isomers of dinitrophenol: 2,3- ... 5-Dinitrophenol Dinitrophenols also form the core structure of some herbicides, which are collectively referred to as ... Dinofenate Dinoprop Dinosam Dinoseb Dinoterb DNOC Etinofen Medinoterb Wikimedia Commons has media related to Dinitrophenols. ...
An explosive mixture of picric acid and dinitrophenol or picric acid and hexanitrodiphenylamine in a ratio of 70/30. It was ... dinitrophenol was used in naval AP shells. Amatol continued in field use to 1945 when it began to be replaced by a 60/40 ... Later shells had 4 c.r. heads, more pointed and hence streamlined than earlier 2 c.r.h. designs. Proper detonation of a lyddite ... Cartridges were sometimes made up of fractions of charges e.g. a 6-inch gun cartridge may be made up of 2 x 1/2 charges or 1 x ...
... dinitrophenols MeSH D02.640.743.304.250 - 2,4-dinitrophenol MeSH D02.640.743.400 - 2-hydroxy-5-nitrobenzyl bromide MeSH D02.640 ... dinitrophenols MeSH D02.755.566.304.500 - 2,4-dinitrophenol MeSH D02.755.566.400 - 2-hydroxy-5-nitrobenzyl bromide MeSH D02.755 ... 4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide MeSH D02.092.146.325 - p-dimethylaminoazobenzene MeSH ... vitamin k 2 MeSH D02.455.849.291.523.500.922 - vitamin k 3 MeSH D02.455.849.291.850 - taxoids MeSH D02.455.849.291.850.777 - ...
646 (1-2): 119-22. doi:10.1016/j.aca.2009.05.023. PMID 19523564. Goodarzi MT, Rafiq M, Turner G (May 1995). "An improved ... 20 (2): 96-100. PMC 2685603. PMID 19503620. Décarie A, Drapeau G, Closset J, Couture R, Adam A (1994). "Development of ... 23 (2): 168S. doi:10.1042/bst023168s. PMID 7672194. (Articles without KEGG source, ECHA InfoCard ID from Wikidata, Pages using ... that is used in many molecular biology applications similarly to other popular haptens such as 2,4-Dinitrophenol, biotin, and ...
5-dinitrophenol 1799 (α,α′-bis(hexafluoracetonyl)acetone) BAM15, N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6 ... 6-dinitrophenol (Dinoterb) 6-sec-butyl-2,4-dinitrophenol (Dinoseb) C4R1 (a short-chain alkyl derivative of rhodamine 19) ... The following compounds are known to be classical uncouplers: 2,4-dinitrophenol (DNP) 2, ... 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene) CZ5 Desaspidin Dicoumarol Dinitro-ortho-cresol (DNOC) Ellipticine Endosidin 9 ( ...
4-dinitrophenol Dinoterb, an herbicide This set index page lists chemical structure articles associated with the same molecular ... an herbicide also known as 6-sec-butyl-2, ...
6-dinitrophenol (picramic acid) and isolated a product belonging to a new class of compounds: Azo dyes. Later, a new class of ... ISBN 1-85532-160-2. OCLC 24796374. Cova, Tânia F. G. G.; Pais, Alberto A. C. C.; Seixas de Melo, J. Sérgio (2017-07-28). " ... 11 (2): 177-205. doi:10.1007/pl00003863. ISSN 0936-9937. S2CID 12992663. Centeno, Silvia A.; Buisan, Virginia Lladó; Ropret, ... It has the chemical formula FeIII 4 [ FeII ( CN ) 6 ] 3 {\displaystyle {\ce {FeIII4[FeII(CN)6]3}}} . With a history dating back ...
Dinitrophenol was included in the Poisons Act 1972 poisons list order 1972. However DNP was dropped from the list in 1982. In ... "Dinitrophenol (DNP) and the Death of Eloise Parry" (PDF). "Eloise Parry: Man convicted over diet pill death". BBC News. 9 ... "Toxicological Profile for Dinitrophenols" (PDF). Agency for Toxic Substances and Disease Registry. U.S. Department of Health ... Simkins, S. (1937). "Dinitrophenol and desiccated thyroid in the treatment of obesity: a comprehensive clinical and laboratory ...
Receive NAPRA updates of interest directly to your inbox: general NAPRA news, NDS updates and/or updates on practice resources.. ...
reaction of 2,4 dinitrophenol.... what will be the reaction between the 2, 4 dinitrophenol and concentrated acid sulfuric?. ... 2-hydroxy-4,6-dinitrobenzenesulphonic acid. I think the latter would predominate as there are two nitro groups and so twice the ... Sciencemadness Discussion Board » Fundamentals » Organic Chemistry » reaction of 2,4 dinitrophenol.... Select A Forum. ... Sciencemadness Discussion Board » Fundamentals » Organic Chemistry » reaction of 2,4 dinitrophenol.... Select A Forum. ...
Use of Dinitrophenol in Nutritional Disorders?: A Critical Survey of Clinical Results . American Journal of Public Health and ... DNP: 2,4-Dinitrophenol. Initially used in World War I by French munitions factories, DNP was mixed with picric acid to make ... 2]. So back to the 1933 Stanford study, research showed that small doses of DNP increased basal metabolism by 50%. Worth noting ... 4]. This happens via a separate signaling transduction pathway, independent of the insulin-stimulated glucose uptake pathway, ...
Exposure to dinitrophenols occurs mainly from breathing air, drinking water, or eating food that contains the chemicals. At low ... Dinitrophenols can be removed from the air into water or soil. Once in soil, dinitrophenols can move into groundwater or break ... How can dinitrophenols affect my health?. Most of the information on health effects of dinitrophenols comes from old studies of ... What are dinitrophenols?. Dinitrophenols are a class of manufactured chemicals that do not occur naturally in the environment. ...
Laboratory grade 3-Methyl-2,4-dinitrophenol - CAS 1817-66-9 - GEO-01812 - structure, classification, names, physical and ... 2-(Benzyloxy)-1-bromo-3-nitrobenzene. [688363-79-3]. GEO-04476. 4-Benzyloxy-5-methoxy-2-nitrobenzoic acid. [60547-92-4]. GEO- ...
... CA Name: Phenol,2,4-dinitro- Molecular Structure: 2,4-Dinitrophenol,Phenol,2,4-dinitro-,CAS 51-28-5,184.11, ... C6H4N2O5 2,4-Dinitrophenol,Phenol,2,4-dinitro-,CAS 51-28-5,184.11,C6H4N2O5 Molecular Formula:C6H4N2O5 Molecular Weight: 184.11 ... Sulphur Black 2 on October 30th, 2013 at 3:18 AM […] Methods : 2,4-Dinitrophenol and Picric acid or 2-Amino-4,6-dinitrophenol ... methyl ester 1 N-(2 Ethanol Benzenamine Acetic acid Benzene Butanamide Acetamide 3-Benzenediamine 10-Anthracenedione 10-dihydro ...
6-DINITROPHENOL,O=[N+]([O-])C1C=C([N+](=O)[O-])C(O)=C(F)C=1,C6H3N2O5F,MFCD20486189,2-FLUORO-4,6-DINITROPHENOLfor your research ... 6-DINITROPHENOL, MFCD20486189, 2265-90-9, O=[N+]([O-])C1C=C([N+](=O)[O-])C(O)=C(F)C=1, C6H3N2O5F ... 6-DINITROPHENOL order, 2-FLUORO-4,6-DINITROPHENOL manufacturer, 2265-90-9 buy, 2265-90-9 purchase, 2265-90-9 price, 2265-90-9 ... 6-DINITROPHENOL buy, 2-FLUORO-4,6-DINITROPHENOL purchase, 2-FLUORO-4,6-DINITROPHENOL price, 2-FLUORO-4,6-DINITROPHENOL ...
These samples were analyzed for a total of 286 chemicals.6 See Figures D-1 and D-2 in Appendix D for the number of off-site ... These samples were analyzed for a total of 319 chemicals.7 See Figures D-3 and D-4 in Appendix D for the number of off-site ... Figure 2. Demographics Within a 5-Mile Radius of the ORR. By presenting decade-by-decade size comparison for the available ... 4For chemicals detected in at least 10 percent of the samples, the second-tier screening concentrations were calculated using ...
In no event shall Vanderbilt be liable for any damages or other liability to you or any other users of the eMERGESPHINX.org website beyond $1,000 per user. To the maximum extent permitted by law, in no event shall Vanderbilt or any of its affiliates be liable for any special, punitive, indirect, incidental or consequential damages, including but not limited to personal injury, wrongful death, loss of goodwill, loss of use, loss of profits, interruption of service or loss of data, whether in any action in warranty, contract, tort or any other theory of liability (including, but not limited to negligence or fundamental breach), or otherwise arising out of or in any way connected with the use of, reliance on, or the inability to use, the eMERGESPHINX.org website or any service offered through the eMERGESPHINX.org website or any material or information contained in, accessed through, or information, products or services obtained through this website, even if an authorized representative of ...
2 (reliable with restrictions). Rationale for reliability incl. deficiencies:. other: Data have been obtained from secondary ...
1-2, 10.2003, p. 159-164.. Research output: Contribution to journal › Conference article › peer-review ... Strains Funis 2-1, SUG 2-2, OK1-50 and NASF-1, respectively, are resistant to molybdenum, mercury, sulfite and 2,4- ... dinitrophenol (2,4-DNP). In contrast, strain AP19-3 is sensitive to all these toxic compounds. Cytochrome oxidase is one of the ... Strains Funis 2-1, SUG 2-2, OK1-50 and NASF-1, respectively, are resistant to molybdenum, mercury, sulfite and 2,4- ...
... α-Dinitrophenol,2,4-DNP,DNP; Linear Formula: (O2N)2C6H3OH; find Supelco-34334 MSDS, related peer-reviewed papers, technical ... 2,4-Dinitrophenol PESTANAL®, analytical standard; CAS Number: 51-28-5; EC Number: 200-087-7; Synonyms: ... 2,4-Dinitrophenol is called as an uncoupler of oxidative phosphorylation, which can prevent adenosine triphosphate(ATP) ... 2,4-Dinitrophenol is called as an uncoupler of oxidative phosphorylation, which can prevent adenosine triphosphate(ATP) ...
2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. J Med Toxicol. 2011 Sep. 7(3): ... Hemoglobin F-Cincinnati, alpha 2G gamma 2 41(C7) Phe--,Ser in a newborn with cyanosis. Am J Hematol. 1995 May. 49(1):43-7. [ ... Palmer K, Dick J, French W, Floro L, Ford M. Methemoglobinemia in Patient with G6PD Deficiency and SARS-CoV-2 Infection. Emerg ... The level of NADH reductase is low at birth and increases with age; it reaches adult levels by age 4 months ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. J Med Toxicol. 2011 Sep. 7(3): ... Hemoglobin F-Cincinnati, alpha 2G gamma 2 41(C7) Phe--,Ser in a newborn with cyanosis. Am J Hematol. 1995 May. 49(1):43-7. [ ... Palmer K, Dick J, French W, Floro L, Ford M. Methemoglobinemia in Patient with G6PD Deficiency and SARS-CoV-2 Infection. Emerg ... The level of NADH reductase is low at birth and increases with age; it reaches adult levels by age 4 months ...
Dinitrophenol ... Document Number: 4. Full Record. Main Title. Causes of death of ... 2-chloroethyl vinyl ether--Toxicology ; Anesthetics ; Sedatives Additional Subjects. United States--Toxic Substance Control Act ... 110-75-8 ; (2-chloroethoxy)Ethene; Vinyl 2-chloroethyl ether; vinyl beta-chloroethyl ether ; 2-chloroethyl ethenyl ether. ... 4-Dinitrophenol, Tricaine. Methanesulfonate and 1-Octanol.. Author. McKim, J. M. ; Schmieder, P. K. ; Carlson, R. W. ; Hunt, E ...
The isomers of 2-butene-1,4-diol can be separated on both chiral columns while the isomers of lafutidine can only be resolved ... The resolution of cis and trans isomers of 2-butene-1,4-diol was 2.61 on (S,S)-Whelk-O 1 column with hexane-ethanol (97:3, v/v ... The Bcl-2 family of proteins stands among the most crucial regulators of apoptosis and performs vital functions in deciding ... 2-(2-Hydroxy)benzylideneaminonaphthothiazole was converted to its Co(II), Ni(II) and Cu(II) metal complexes upon treatment ...
6-dinitrophenol. 2000 µg/mL. CAS #: 534-52-1 ...
6-dinitrophenol. P016. 542-88-1. Dichloromethyl ether. P036. 696-28-6. Dichlorophenylarsine. ... 55-91-4. Phosphorofluoridic acid, bis(l-methylethyl) ester. P089. 56-38-2. Phosphorothioic acid,_O,Q-diethyl O-(4-nitro- phenyl ... 2,7:3,6-Dimethanonaphth[2,3-b]oxirene, 3,4,5,6,9,9-hexacMoro-la,2,2a,3,6,6a,7,7a-octahydro-, (I aalpha,2beta,2abeta,3alpha, ... Phosphoric acid, diethyl 4-nitrophenyl ester. P039. 298-04-4. Phosphorodithioic acid, O,O-diethyl S-[2- (ethylthio)ethyl] ester ...
Journal of Pharmacology and Experimental Therapeutics November 1, 1997, 283 (2) 611-618; ... Journal of Pharmacology and Experimental Therapeutics November 1, 1997, 283 (2) 611-618; ... Journal of Pharmacology and Experimental Therapeutics November 1997, 283 (2) 611-618; ...
6-dinitrophenol as an internal standard (IS). Water was used as the extraction solvent. The retention times of CMP and internal ... Advanced Search Search Help About NIOSHTIC-2 Feedback Terms: metalworking OR metal working OR cutting OR machining OR ... A rapid HPLC analysis for dermal penetration: the case study of 4-chloro-3-methylphenol (CMP) from metal working fluid Trim VX ... A rapid and simple HPLC method has been developed for the determination of 4-chloro-3-methylphenol (CMP) in the metal working ...
6-dinitrophenol, 4-amino-5-hydroxy 2,7-naphthalenedisulfonic acid, 4-nitrobenzenamine and resorcinol, sodium salts. ...
6-dinitrophenol; 3,5-Dinitro-2-hydroxytoluene; 4,6-Dinitro-o-cresol; 4,6-Dinitro-o-cresolo [Italian]; 4,6-Dinitro-o-kresol [ ... Secondary acute renal failure after dinitrophenol and dinitro-o-cresol poisoning has been reported. [LaDou, p. 418] 4,6-Dinitro ... 2; Dwunitro-o-krezol [Polish]; Effusan; Effusan 3436; Elgetol; Elgetol 30; Elipol; Extrar; Flavin-Samdoz; Hedolit; Hedolite; K ... Dinitro-ortho-cresol; 2,4-Dinitro-6-methylphenol; 2,4-Dinitro-o-cresol; 2-Methyl-4, ...
4 Biggest Lies of The Biggest Loser. Its a show about fitness that keeps people dumb and in the dark about getting fit. Heres ... 2,4-Dinitrophenol). But what really got me interested in DNP was the idea that I could eat whatever I wanted and still lose an ... I started out with Dans originally recommended dose of between 2-3mgs/kg of body weight (I took a 200mg cap and Im about 90- ... I first heard about DNP (2,4-Dinitrophenol) in a free tape (as in "audio cassette" for the younger readers) that I received as ...
I tried T-2 or whatever it used to be from biotest for awhile. it seemed to me that it depended on which bottle I took it out ... took the usual 2 caps with cex 30min to workout. fridays are my shoulder days. 10min of light cardio as warm up. moved onto ... Ok well it seems like the 2 most popular are Scorch and T-Rex so between those 2 which one is better and why? Also how do they ... What worked for me ... 2 MONTHS OF STACKER 2 W/ephedra. Does anyone know where to get some stacker 2 w ephedra, therez a lot in ...
dinitrophenol, 2,4-. 00051-28-5. dinitrotoluene, 2,4-. 00121-14-2. ... Amplifies: 3704.03(F)(3)(c), 3704.03(F)(4) Five Year Review Date: 5/8/2025 Prior Effective Dates: 12/1/2006 ... A) Except where exempt under division (F)(4) of section 3704.03 of the Revised Code, the director may require a permit-to- ... toluene-2,4-diisocyanate or 2,6-diisocyanate (or as a mixture). 00584-84-9; 00091-08-7. ...
  • The high surface area of GdVO4/FG was suited for adsorption coupled photocatalysis involving mineralization of phenol and 2, 4-dinitrophenol (DNP) in aqueous medium. (lancs.ac.uk)
  • An isocratic HPLC method for the determination of phenol and nitrophenols (4-nitrophenol, 2-nitrophenol, 4,6-dinitro-o-cresol and 2,4-dinitrophenol) has been developed and validated using 2-chlorophenol as internal standard (IS) and a monolithic column in tap water samples. (chromatographyonline.com)
  • The sensitivity of the biosensor response to four phenol compounds: phenol, catechol, 3-cresol and 4-chlorophenol was examined, as well as possible interactions between phenols, according to 24 factorial experiment. (edu.pl)
  • 4. There are three nitro groups attached at ortho and para position of phenol. (harti.co)
  • From the Journal of Clinical Toxicology, Volume 44, Issue 3 (2006): Dinitrophenol uncouples oxidative phosphorylation, causes release of calcium from mitochondrial stores and prevents calcium re-uptake. (wikipedia.org)
  • 2,4-Dinitrophenol is called as an uncoupler of oxidative phosphorylation, which can prevent adenosine triphosphate(ATP) synthesis, but it permits electron transfer to proceed. (sigmaaldrich.com)
  • The oxidative radical species OH center dot and O-2(center dot-) played vital role in photodegradation and disinfection process. (lancs.ac.uk)
  • Five of the chemicals appeared to share a common mode of toxic action, the uncoupling of oxidative phosphorylation: 2,4-DNP, DNOC, dinoseb, PCP, and hexachlorophene. (wisconsin.edu)
  • Dinitrophenol uncouples oxidative phosphorylation, causes release of calcium from mitochondrial stores and prevents calcium re-uptake. (buydnp.co)
  • 1 There are drugs that inhibit mitochondrial oxidative phosphorylation, like carbon monoxide 2 , hydrogen sulfide 3 , and of course, cyanide . (toxandhound.com)
  • But the ones I find the most interesting are toxins that uncouple oxidative phosphorylation, like dinitrophenol 4 and aspirin ( salicylate ). (toxandhound.com)
  • The ATSDR's Toxicological Profile for Dinitrophenols remarks that DNP elimination appears to be rapid except when liver function is impaired. (wikipedia.org)
  • I started out with Dan's originally recommended dose of between 2-3mgs/kg of body weight (I took a 200mg cap and I'm about 90-95kgs). (t-nation.com)
  • The purpose of this work is the development of a controlled-release nanoformulation of 2,4-dinitrophenol derivatives for intravenous administration. (publichealthtoxicology.com)
  • The results open up the perspectives for future application of liposomes and polymer micelles of 2,4-dinitrophenol derivatives as a proton ionophores, whose task is to transfer protons to the mitochondria with the heat dissipation, that leads to accelerated fats oxidation and, as a result, harm-free medical treatment of T2DM and NAFLD. (publichealthtoxicology.com)
  • EC (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. (uchicago.edu)
  • EC (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol. (uchicago.edu)
  • 2-(2'-Hydroxy)benzylideneaminonaphthothiazole was converted to its Co(II), Ni(II) and Cu(II) metal complexes upon treatment with metal salts in ethanol. (researchgate.net)
  • L-Carnitine CAS 541-15-1 Levocarnitine 3 Lose Weight Steroids For Cutting Weight L-carnithine Quick Detail of L-Carnitine Synonyms:3- carboxy-n,n,n-trimethyl-2-propen-1-aminium chloride;3-hydroxy-4-(trimethylam. (pharmacy-steroids.com)
  • The term represents a wide range of substances (see the other types of PIEDs section), but the oldest and largest group are non-prescribed anabolic-androgenic steroids (AAS), which have been used since at least the late 1940s [2] . (snhn.net)
  • The reducing sugars react with Picric Acid (toxic yellow crystalline solid) also chemically known as 2,4,6-trinitrophenol (TNP) to form a red coloured Picramic Acid. (harti.co)
  • what will be the reaction between the 2, 4 dinitrophenol and concentrated acid sulfuric? (sciencemadness.org)
  • A review of environmental data collected during two previous surveys in the quality control laboratory, one by the Occupational Safety and Health Administration (OSHA) and one by a private industrial hygiene consultant, did not indicate the presence of detectable levels of sulfur dioxide in 4 samples collected, sulfuric acid in 7 samples, selenium in 2 samples, or 2,4-dinitrophenol in 1 sample. (cdc.gov)
  • The N-terminal amino acid of SUG 2-2 α-subunit was blocked. (elsevier.com)
  • These results indicate that A. ferrooxidans strains resistant to Mo 5+ , Hg 2+ , sulfite and 2,4-DNP have a cytochrome oxidase different from that of the sensitive strain AP19-3 with respect to apparent molecular size as well as N-terminal amino acid sequence. (elsevier.com)
  • def: The chemical reactions and pathways resulting in the formation of methanopterin, an N-[1′-(2″-amino-4″-hydroxy-7″- methyl-6″- pteridinyl)ethyl]-4-[2′,3′,4′,5′- tetrahydroxypent-1′- yl (5′→1″) O-α-ribofuranosyl-5″-phosphoric acid] aniline, in which the phosphate group is esterified with α-hydroxyglutaric acid. (geneontology.org)
  • These acid-sensitive mutants were unable to grow at pH 5·0 in the presence of 1-5 μM CCCP, a concentration not lethal to the wild-type strain mc 2 155. (microbiologyresearch.org)
  • Acid-sensitive mutants of Salmonella typhimurium identified through a dinitrophenol lethal screening strategy. (microbiologyresearch.org)
  • Both salicylate and 2,6 dihydroxybenzoic acid suppressed TNFα-induced IκB degradation, and in genetic knockout experiments, we found that the effect of salicylate on IκB degradation was AMPK-independent. (hw.ac.uk)
  • Picric acid (2,4,6‐trinitrophenol, picronitric acid) is a pale yellow, odorless crystal that is slightly soluble in water. (harti.co)
  • Picric Acid (2,4,6 Trinitrophenol) is frequently found in forensic laboratories for use in the Christmas Tree stain (1) and for Urine detection (2). (harti.co)
  • It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. (modst.nl)
  • 99.5% Dioctyl Phthalate, Phthalic Acid Dinonyl Ester, DOP manufacturer / supplier in China, offering 99.5% Dioctyl Phthalate (DOP) for Industrial Grade, High Quality PAM (Polyacrylamide, Anionic) Flocculant in Water Treatment Industry, High Quality Sodium 2, 4-Dinitrophenol DNP Powder CAS 1011-73-0 with Best Price and so on. (modst.nl)
  • reaction of 2,4 dinitrophenol. (sciencemadness.org)
  • Sciencemadness Discussion Board » Fundamentals » Organic Chemistry » reaction of 2,4 dinitrophenol. (sciencemadness.org)
  • Subject: reaction of 2,4 dinitrophenol. (sciencemadness.org)
  • Schiff bases were synthesized by the reaction of naphtha[1,2-d]thiazol-2-amine with various substituted aromatic aldehydes. (researchgate.net)
  • The only availlable estimated rate constant for the reaction of vapour-phase from data of 2,4-DNP with hydroxyl radicals is 5.76x10-13cm3/molecule-second. (europa.eu)
  • Since dinitrophenols are expected to be present partly in the particulate phase in the air, the reaction rate is expected to be even slower than the estimated value for the gas phase reaction (Atkinson R. 1988). (europa.eu)
  • The first, using the Atkinson method estimates the rate constant for the reaction of vapor-phase 2,4-DNP with hydroxyl radicals at 5.76x10^-13cm3 molecule-second. (europa.eu)
  • Another SRC estimation sets the rate constant for the vapour-phase reaction of 2,4 -DNP with photochemically-produced hydroxyl radicals has been at 6.6X10^-13 cm3/molecule-sec at 25 °C using a structure estimation method SRC. (europa.eu)
  • Dinitrophenol (10-4 M), cyanide (10-3 M), and deoxyglucose (10-2 M) inhibited the HCO3- flux by 39 per cent, 37 per cent, and 38 per cent, respectively. (jci.org)
  • DNP is particularly useful as a herbicide alongside other closely related dinitrophenol herbicides like 2,4-dinitro-o-cresol (DNOC), dinoseb and dinoterb. (wikipedia.org)
  • Dioctyl phalate (DOP) or Bis(2-ethylhexyl) phthalate is a colorless, odorless, and oily organic compound with the chemical formula of C 24 H 38 O 4.It is a famous plasticizer that has been used for flexible polyvinyl chloride (PVC) plastic production due to its low price. (modst.nl)
  • en] Dioctylphthalate Di octyl phthalate (DOP) is an organic compound with the formula C6H4(C8H17COO)2. (modst.nl)
  • In fulfilment of the target, we used 2,4-dinitrophenol esters with various substituent lengths loaded into liposomes of various lipid composition and polymeric micelles based on poly-(L-lactide-co-)glycolide (PLGA). (publichealthtoxicology.com)
  • An effective 3-fold increase in the encapsulation of 2,4-dinitrophenol esters into liposomes in comparison with free molecule was observed. (publichealthtoxicology.com)
  • We also demonstrated the possibility of 2,4-dinitrophenol esters to encapsulate in nanoparticles of PLGA block copolymer. (publichealthtoxicology.com)
  • The effect of 2 protein synthesis inhibitors (cycloheximide and fluorophenylalanine) on the appearance of aflatoxin B1 synthetase activity was studied. (usda.gov)
  • 2,4-dinitrophenol spikes metabolic rate as potential energy is lost as heat. (factrepublic.com)
  • 2 4 dinitrophenol dnp drug how to buy weightloss capsules online pills powder for bodybuilding weight fat loss buying pills supplement . (dietsupplementreviews.org)
  • Aqueous extracts of the leaves inhibited HIV-1 infection and replication in the lymphoid cell line MOLT-4 4 . (ethnoleaflets.com)
  • Hexavalent chromium hexavalent chromium was described in victims of acute promyelocytic leukemia (apl) cells when therapeutic doses of antivenom), the antivenom infusion is restarted at 1-4 ml/h while continuing their daily activities of daily living by the international agency for toxic substances in which an individual plan of care. (childbirthsolutions.com)
  • Canadians should not buy or use health products that contain 2,4-dinitrophenol, more commonly known as DNP, because it is toxic and can cause death. (pharmacy-online-cialis.com)
  • In the 1940s and earlier, factory workers who breathed or came in contact with high amounts of dinitrophenols for a short and long period of time experienced fever, sweating, restlessness, decreases in white blood cells, and sometimes death. (cdc.gov)
  • Effects of the inhibitor molecule 2,4-dinitrophenol (DNP) on multiple isolated chloroplast concentrations were assayed using a redox dye, 2,6-dichlorophenolindophenol (DCPIP). (drnurvus.com)
  • The renal excretion of 2-deOxy-D-glucose (2DG) in dogs and rats has been studied using the standard clearance and stop-flow techniques. (aspetjournals.org)
  • Intragastric administration of deoxyandrographolide , andrographolide , neoandrographolide or 11 ,12 -didehydro- 14-deoxyandrographolide (100 mg/kg body weight) to mice, rats or rabbits reduced pyrexia induced by 2,4-dinitrophenol or endotoxins 14 . (ethnoleaflets.com)
  • In view of this,they were investigated in this study with the rectal temperature change as an indicator and 2,4-dinitrophenol-induced fever rats as subjects. (bvsalud.org)
  • It is called as 2,4-Dinitrophenol, which is a supplement commonly used for fast and extreme weight loss, very popular among all the high-level bodybuilders along with the general public who would like to lose weight in the safest manner. (buydnp.co)
  • And is a long-acting testosterone commonly prescribed once every 2 weeks. (linda-stern.com)
  • The chemical formula for 2,4-dinitrophenol is C H N O and the molecular weight is 184.11 g/mol. (realityviews.in)
  • Inclusion of cycloheximide and 2,4-dinitrophenol in the bathing medium permitted a continuing efflux of sucrose amounting to 5- to 10-fold increases over that obtained with distilled water. (upr.edu)
  • 2 Oral - Acute Tox. (sigmaaldrich.com)
  • ACGIH] Secondary acute renal failure after dinitrophenol and dinitro-o-cresol poisoning has been reported. (haz-map.com)
  • We found, for example, that H4IIE cells were exquisitely sensitive to uncoupling with modest doses of salicylate, which occurred on a similar time course to another anti-hyperglycaemic uncoupling agent 2,4-dinitrophenol, while there was no discernible effect at all of two salicylate analogues which are not anti-hyperglycaemic. (hw.ac.uk)
  • These tests cannot predict whether you will have health problems from the exposure to dinitrophenols. (cdc.gov)
  • We tested the hypothesis that inducible isoform of nitric oxide synthase (iNOS)-derived nitric oxide (NO) inhibits oxygen consumption (Vo 2 ) in human intestine resected for necrotizing enterocolitis (NEC). (nature.com)
  • One of the promising molecules that can be effective in the treatment of NAFLD and T2DM is 2,4-dinitrophenol, which acts as a proton ionophore, transferring protons into the mitochondrial matrix with the release of heat. (publichealthtoxicology.com)
  • Taking illegal diet pills or supplements that contain dinitrophenols will expose you to this chemical. (cdc.gov)
  • It is important not to purchase or take illegal diet pills or supplements that have dinitrophenols in them as these can cause serious health problems, including death. (cdc.gov)
  • 4 management of fibromyalgia There are often 75'300 grams of carbs and 20'60 grams of protein per serving of these high-calorie supplements, testosterone cypionate dose epocrates. (linda-stern.com)
  • LaDou, p. 418] 4,6-Dinitro-o-cresol is a potential skin sensitizer. (haz-map.com)
  • Forty-five patients were divided into three groups to receive epidurally administered saline (Group S), 1.5% (w/w) lidocaine (Group L), or 0.5% (w/w) ropivacaine (Group R). Propofol infusion was started to produce blood concentration of 4 mug/ml. (researchgate.net)
  • Initial efflux was rapid up to about 4 hours, achieving a maximum external sugar concentration between 8 and 12 hours, followed by depletion of sucrose in the bathing medium. (upr.edu)
  • A significant correlation was present between buffer NO concentration and Vo 2 in NEC-healthy tissue. (nature.com)
  • Buffer pH was 7.43 ± 0.05 when aerated with 21% O 2 , 5% CO 2 , bal N 2 at 37°C, whereas buffer O 2 concentration was 222 ± 3 nM O 2 /mL. (nature.com)
  • A rapid HPLC analysis for dermal penetration: the case study of 4-chloro-3-methylphenol (CMP) from metal working fluid Trim VX. (cdc.gov)
  • A rapid and simple HPLC method has been developed for the determination of 4-chloro-3-methylphenol (CMP) in the metal working fluid (MWF), Trim VX and in experiments designed to measure the dermal penetration of CMP from MWF. (cdc.gov)
  • Both types of antibodies with complementary specificity are hypothesized to stimulate 2 populations of T lymphocytes. (techblessing.com)
  • Coselection of the 2 populations network marketing leads to a fresh stable steady condition of the machine with reduced reactivity to BL/6 tissues. (techblessing.com)
  • Combining first-cover pesticides [azinphosmethyl (guthion) and cis-N-(trichloromethyl)thio)-4-cy-clonexane-l,2-dicarboximide (captan)] with NAA, and captan with carbaryl, produced satisfactory thinning. (ashs.org)
  • Dinitrophenols are a class of manufactured chemicals that do not occur naturally in the environment. (cdc.gov)
  • In early December 2017, federal authorities executed a search warrant at the Sacramento-area facilities of Enhanced Athlete, looking for the SARM ostarine, as well as 2,4-Dinitrophenol (DNP) and other research chemicals. (hourofscampering.com)
  • In the 1930s 2,4-dinitrophenol was used in diet pills but was banned for this use in 1938 because of health risks. (cdc.gov)
  • Most of the information on health effects of dinitrophenols comes from old studies of patients who were prescribed diet pills containing dinitrophenol before it was banned. (cdc.gov)
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  • 2,4-Dinitrophenol at a dose of 1 mg/ kg/ min did not influence the reabsorption of either sugar. (aspetjournals.org)
  • Tests are available to measure levels of dinitrophenols and its breakdown products in blood and urine. (cdc.gov)
  • Animal by-products, 2,4-dinitrophenol, beef and alcohol are among the product categories that have been part of food crime investigations by units in the United Kingdom. (foodsafetynews.com)
  • To support the ongoing research efforts on Coronavirus SARS-CoV-2 causing COVID-19 disease, we've provided easy access to critical products needed for virus research and detection. (vwr.com)
  • A 50% methanol extract of the leaves inhibited growth in vitro of Proteus vulgaris 2 . (ethnoleaflets.com)
  • To test this hypothesis, intestinal Vo 2 and NO production were measured under in vitro conditions in human intestine resected for NEC, as well as in human intestine resected from infants for reasons other than NEC. (nature.com)
  • The pills contained 2,4 dinitrophenol dnp, and cats. (photoglamour.it)
  • During World War 2, Russian soldiers took "heat pills" that kept them warm in the winter. (factrepublic.com)
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