The main objective of the work was to evaluate the influence of a six day supplementation with sodium phosphate on circulatory and pulmonary variables, the level of 2,3-diphosphoglycerate (2,3-DPG) and the concentration of inorganic phosphates in blood serum of elite off-road cyclists. The research material included 19 cyclists which were randomly divided into a experimental group, supplemented with sodium phosphate and a control group receiving a placebo The subjects in the experimental group ingested sodium diphosphate in a dose of 50mg/kg of fat free mass per day. The supplement was ingested in even doses, four times per day. The control group received 4g of glucose in gelatin capsules (500mg), which were also divided into 4 even portions. During the experiment a significant (p,0.05) increase in maximal oxygen uptake was observed (VO2max), maximal minute ventilation (VEmax), as well as oxygen pulse (O2/HR). Also a significant decrease in resting and maximal exercise heart rate occurred. ...

2,3-Bisphosphoglycerate mutase (2,3-BPGM), an erythroid-expressed enzyme, synthesises 2,3-bisphosphoglycerate (2,3-BPG), the allosteric modulator of haemoglobin. This ligand has a higher affinity for adult haemoglobin than for fetal haemoglobin and differential binding of it facilitates transfer of oxygen between adult and fetal blood by lowering the affinity of adult haemoglobin for oxygen. This paper reports the discovery that 2,3-BPGM is synthesised in non-erythroid cells of the human placenta. Western blot analysis of placental extracts revealed high levels of 2,3-BPGM in the human placenta. Immunohistochemical staining and in situ hybridisation experiments indicated that abundant 2,3-BPGM is present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface. A cytochemical staining technique showed that the placental 2,3-BPGM is active, indicating that 2,3-BPG is synthesised in the outermost cells of the placenta. These observations demonstrate an unexpected and abundant

Serum inorganic phosphorous was decreased significantly on the third postoperative day following cardiac surgery in 18 patients initially studied. Reduced plasma inorganic phosphate has been shown to cause a reduced concentration of red cell organic phosphates, an important determinant of hemoglobin-oxygen affinity. Therefore, 10 consecutive patients were studied to determine if reduced 2,3-diphosphoglycerate (DPG) and adenosine triphosphate (ATP) concentration and increased hemoglobin-oxygen affinity accompanied the fall in serum inorganic phosphate concentration. A significant fall in 2,3-DPG and an increase in hemoglobin-oxygen affinity was present in red cells of patients studied on the first postoperative day. A reduction in red cell ATP was also present and persisted for 5 days during which time red cell 2,3-DPG returned to levels which were in excess of preoperative values. The reduction in serum inorganic phosphorous followed the reduction in red cell 2,3-DPG and correlated with the ...

2;3-Diphosphoglycerate/*analysis, Adenosine Triphosphate/*analysis, Biological Markers/analysis, Blood Preservation/*standards, Erythrocyte Aging, Erythrocytes/*chemistry, Hemolysis, Humans, Observer Variation, Plateletpheresis ...

Moriyama R, Lombardo CR, Workman RF and Low PS. Department of Chemistry, Purdue University, West Lafayette, Indiana 47907-1393.. In addition to reducing hemoglobin-O2 affinity, 2,3-diphosphoglycerate (DPG) is known to modulate the mechanical properties of the erythrocyte membrane. By fluorescence spectroscopy and differential scanning calorimetry, we demonstrate that DPG binds the cytoplasmic domain of erythrocyte membrane band 3 in two stages characterized by apparent KD values of approximately approximately 2 and 12 mM. DPG was also shown to perturb the stability of ankyrin, protein 4.1, and protein 4.2 in situ and to directly bind to protein 4.1. In studies of membrane-skeleton interactions, DPG was observed to inhibit the fast and slow phases of ankyrin binding to band 3 and to reduce both the number of ankyrin sites and affinity of ankyrin for each class of site. The inhibition was biphasic, similar to the band 3-DPG binding isotherm; however, at physiological DPG concentrations a ...

Coordenadas: 46° 23 46" N 112° 43 58" O Deer Lodge é uma cidade localizada no estado americano de Montana, no Condado de Powell, do qual é sede. Segundo o censo americano de 2000, a sua população era de 3421 habitantes. Em 2006, foi estimada uma população de 3311, um decréscimo de 110 (-3.2%). De acordo com o United States Census Bureau tem uma área de 3,7 km², dos quais 3,7 km² cobertos por terra e 0,0 km² cobertos por água. Deer Lodge localiza-se a aproximadamente 1379 m acima do nível do mar. O diagrama seguinte representa as localidades num raio de 36 km ao redor de Deer Lodge. Deer Lodge Condado de Anaconda-Deer Lodge (36 km) Avon (25 km) Elliston (29 km) Garrison (17 km) U.S. Census Bureau. Census 2000 Summary File 1 U.S. Census Bureau. Estimativa da população (julho de 2006) U.S. Board on Geographic Names. Topical Gazetteers Populated Places. Gráficos do banco de dados de altitudes dos Estados Unidos da América Estatísticas, mapas e outras informações sobre ...

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.

The Winnipeg Regional Health Authoritys Deer Lodge Centre is a progressive 431 bed long-term care, geriatric rehabilitation and chronic care facility located in Winnipeg, Manitoba. Several years ago, Deer Lodge staff looked at their falls statistics and their numbers told them that they could do better. They developed policies, protocols and algorithms to address falls risk and implemented a screening process for everyone admitted to the facility. Their fall rates went down close to 30 per cent over three years, but when they looked at the national standards they found there was still room for improvement. In September 2011, Deer Lodge Centre joined the Safer Healthcare Now! Falls Facilitated Learning Series, a six-month virtual program designed to assist organizations working on reducing falls and injury from falls.. "We are using the Falls Facilitated Learning Series to take a look at hourly rounding," says Daryl Dyck, Clinical Nurse Specialist at Deer Lodge Centre. "On one unit we did a ...

Definition of Phosphoglyceromutase with photos and pictures, translations, sample usage, and additional links for more information.

Deer Lodge è una città degli Stati Uniti dAmerica situata in Montana, nella contea di Powell. Altri progetti Wikimedia Commons Wikimedia Commons contiene immagini o altri file su Deer Lodge (EN) Deer Lodge, in City-data.com, Advameg Inc ...

The chief characteristics of the blood of the turtle Pseudemys concinna, considered as a system for the transport of oxygen and carbon dioxide, are its low corpuscular content (10 to 22 per cent by volume) and its high concentration of base bound as bicarbonate.. These characteristics account fully for the shape and position of the carbon dioxide dissociation curve, the effect of oxygenation and reduction of the hemoglobin upon the carbon dioxide-combining power of the blood, and the distribution of carbon dioxide between the corpuscles and plasma.. The oxygen-combining capacity of the turtle corpuscles does not differ from that of an equal volume of human erythrocytes. The oxygen dissociation curve is similar to that of mammalian blood and is affected in like manner by the quantity of carbon dioxide present. Its exact shape and position depend in part upon the number of corpuscles in the blood; in part its characteristics cannot be attributed to known chemical factors.. ...

1. Oxygen-binding, plasma and intra-erythrocytic pH, and haemoglobin, 2,3-diphosphoglycerate and inorganic phosphate concentrations were measured in sixty-two healthy non-smokers aged between 18 and 89 years.. 2. P50 (oxygen tension at 50% oxygen saturation) expressed at plasma pH 7·40 and Pco2 5·33 kPa showed a positive correlation with age.. 3. This correlation of P50 with age was closer when P50 was expressed at a constant intra-erythrocytic pH 7·20. On average P50 at intra-erythrocytic pH 7·20 increased from 3·59 kPa at 20 years to 3·96 kPa at 90 years of age.. 4. 2,3-Diphosphoglycerate, inorganic phosphate, haemoglobin and mean corpuscular haemoglobin concentrations did not correlate with P50 or with age.. ...

Dihydroxyacetone: A ketotriose compound. Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent.

The oxygen dissociation curve is s shaped which means that increasing ventilation to units with high VQ ratios cannot compensate for the shunt caused by low VQ ...

Mon Dec 21 00:00:00 MST 2009. A fur handling workshop is scheduled for Saturday, Jan. 9, 2010 in Deer Lodge. The all-day workshop, sponsored by the Montana Trappers Association, will offer information and demonstrations on fur handling safety, ethics and techniques. There is no charge for the workshop, and students of all ages are welcome. The class will be held from 9 a.m. to 4 p.m. at Spark and Arc Welding, 604 Mitchell St. in Deer Lodge. To register, contact Ed Hebbe III at 406-846-2304. Workshop participants should bring a chair, lunch and dress warmly. ...

Rock Creek Cattle Company in Deer Lodge, MT: View TripAdvisors 5 unbiased reviews, photos, and special offers for Rock Creek Cattle Company, #2 out of 3 Deer Lodge specialty lodging.

Reducing blood oxygen affinity may enhance myocardial oxygen delivery during ischemia. We evaluated this hypothesis in awake, previously instrumented dogs that received a 20 ml/kg infusion of a solution of dihydroxyacetone, phosphate, and pyruvate after acute occlusion of either the left anterior descending or circumflex coronary artery. This infusion reduced blood oxygen affinity (BOA) after 2 hours; the P50 increased from 29.9 +/- 0.7 torr (mean +/- SD) to 32.1 +/- 0.6 torr; P less than 0.01 (BOA group). Four dogs received 20 ml/kg of phosphate and pyruvate solution to assess volume effects (V group), and five dogs were controls (C group). The 2-hour P50 values in V and C were unchanged. Regional flow (15-mum spheres) reduction 2 hours postocclusion was compared to the percent tissue infarcted determined by histology 7-9 days after occlusion for multiple samples from the endocardial layer of the left ventricle. When flow was less than 40% of normal, V and C had 55% infarction while BOA had 37% ...

The Audit and Compliance Committee of the Providence St. Joseph Board of Directors approved and updated the Integrity and Compliance Program Description in 2016. The Integrity and Compliance Program (Program) applies to all Providence ministries including our hospitals, clinics, senior and community service entities, university, high school and others. The Program also applies to Providences wholly owned or controlled entities commonly known as Affiliates, including: Swedish Health Services; Swedish Edmonds; Kadlec Health System; Pacific Medical Centers; and other organizations that may join Providence as an Affiliate unless specifically noted otherwise. Providence and its Affiliates are collectively referred to as "Providence" in all compliance related materials. The Program Description is a high level summary of steps Providence implemented to incorporate recommended compliance program guidance from the Department of Health and Human Services Office of Inspector General. Our Program serves as ...

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A new, automated technique for collection and instant preparation of blood components has been developed. The device enables the combined collection of red cells (250 mL) and plasma (475 mL). No adverse effects were seen in the donors. The blood components were of good quality. The impact of the pre-separation temperature on whole blood was studied in two studies. In the first study blood was collected and put into stoppered test tubes. The test tubes were then put into water bath at 15,20,25 and 30 °C. Samples were taken at intervals during 24 hours. The lactate concentration increased and 2,3-DPG concentrations decreased during storage and at a higher rate with higher temperature. In the second study blood was collected and dived into half units. One half unit was actively cooled to 20 °C the other half kept at 28 °C. Blood component preparation was done after 6 hours. There were a significant change in 2,3-DPG, pH and lactate already after two hours hold of the whole blood. The differences ...

cytosol, nucleus, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity, phosphoglycerate mutase activity, canonical glycolysis, gluconeogenesis, glycolytic process, regulation of pentose-phosphate shunt

What happened to the Campus at 3600 Wichita Street in Fort Worth where Masonic Home and School was located?. The property was owned by The Grand Lodge of Texas, not the Masonic Home and School. The Grand Lodge of Texas sold the Campus on January 2, 2007. The Grand Lodge transferred the sale proceeds to Square and Compasses Holding, a 501(c)(3) Texas nonprofit corporation. The mineral interests were owned by The Grand Lodge of Texas. The Grand Lodge of Texas did reserve the mineral interests when it sold the Campus on January 2, 2007. The Grand Lodge, however, subsequently conveyed all of the mineral interests to Square and Compasses Holding, a 501(c)(3) Texas nonprofit corporation on September 21, 2007. Square and Compasses Holding will receive any proceeds from the minerals.. What is Square and Compasses Holding?. Square and Compasses Holding is a 501(c)(3) Texas nonprofit corporation. It currently holds proceeds from the sale of the Campus. It also owns the mineral interests from the Campus. ...

Phosphoglycerate mutase deficiency is a disorder that primarily affects muscles used for movement (skeletal muscles). Beginning in childhood or adolescence, affected individuals experience muscle aches or cramping following strenuous physical activity. Some people with this condition also have recurrent episodes of myoglobinuria. Myoglobinuria occurs when muscle tissue breaks down abnormally and releases a protein called myoglobin, which is processed by the kidneys and released in the urine. If untreated, myoglobinuria can lead to kidney failure.. In some cases of phosphoglycerate mutase deficiency, microscopic tube-shaped structures called tubular aggregates are seen in muscle fibers. It is unclear how tubular aggregates are associated with the signs and symptoms of the disorder. ...

Shop Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase ELISA Kit, Recombinant Protein and Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.

The isolated minor haemoglobin fractions (haemoglobin D) of ostrich, chicken and duck haemoglobin, which constitute about 30% of total intracellular haemoglobin, form crystalline aggregates upon deoxygenation at physiological temperature, ionic strength and pH and at haemoglobin concentrations even well below those present in the red cell. The aggregation is reversed by oxygenation, and can be inhibited by addition of organic phosphates or the corresponding major haemoglobin fraction in a stoichiometric ratio of 1:1. Embryonic haemoglobin from chicken has similar characteristics with respect to its solubility. The results indicate close functional homology of alpha D and embryonic pi-chains as well as a novel role for organic phosphates in the regulation of haemoglobin function. ...

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Cyanate therapy of sickle-cell disease is currently under investigation. Since cyanate-treated erythrocytes have increased oxygen affinity, we studied the effect of chronic cyanate administration on tissue oxygen delivery in rats. Sodium cyanate (CNO) was administered for 8 weeks to two groups of rats. Thirty received 625 mg/kg body weight-week orally, and 30 received 250 mg/kg body weight-week intraperitoneally. Control animals received equivalent amounts of NaCl. Animals were killed at 2, 4, and 8 weeks, and blood oxygen affinity (P50), erythrocyte 2, 3-diphosphoglycerate (DPG), hematocrit, and erythrocyte mass were measured. Tissue oxygen delivery was assessed by skin bubble oxygen tension (SBpO2). ...

Press Release issued Sep 21, 2016: Firstly, Dipropylene glycol (DPG) Market report provides a basic overview of the Dipropylene glycol (DPG) industry including definitions, classifications, applications and Dipropylene glycol (DPG) industry chain structure. Global Dipropylene glycol (DPG) Market analysis is provided for the international market including development history, Dipropylene glycol (DPG) industry competitive landscape analysis, and major regions development status on Dipropylene glycol (DPG) Market scenario.

Spectrofluorometric techniques were used to quantify NADPH-hemoglobin interactions based on the quenching of NADPH fluorescence upon binding to hemoglobin. Fluorometric titrations were carried out with hemoglobin in varied states and with hemoglobins in which the beta-chain anion site is altered. At pH 6.5 in 0.05 M 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid buffer, NADPH binds with high affinity, Kd = 1.03 microM, to deoxy human hemoglobin tetramers. Lower affinity binding of NADPH occurs as the beta-chain anion-binding site is discharged by increasing the pH. Moreover, the cofactor binds in a 1:1 ratio to deoxy tetramers, inositol hexaphosphate binds competitively, and binding is decreased in hemoglobins whose structural alterations result in decreased effects of 2,3-diphosphoglycerate. The cofactor binds to oxidized (met) hemoglobin with an estimated Kd of 33.3 microM but has little or no affinity for the oxy form. These results indicate that NADPH binds at the beta-chain ...

Units of blood were divided into 5 aliquots and were stored at 4 C. in ACD without additive or supplemented with adenine, inosine, inosine adenine, or adenosine. Adenine and nucleoside were added in an amount of 0.75 and 15 micro moles per ml ACD-blood, respectively. After storage for 6 weeks, 24 hour post-transfusion survival of the erthrocytes was determined. Survival of the erthrocytes was significantly increased when the ACD was supplemented with any of the additives. There was, however, no significant difference in the effect of any one of the additives. The glycolytic intermediates of erythrocytes stored for the same period with the same additives were studied after separation on columns of ion-exchange resin. No adenosine triphosphate (ATP) or 2,3-diphosphoglycerate (DPG) remained in the blood stored in ACD alone. Supplementation of ACD with adenine resulted in no qualitative or quantitative change in the intermediates. ATP and DPG remained in the erythrocytes stored in ACD ...

The Phosphoglycerate Kinase 1 is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19.PGK1 is distinguished from testicular PGK2, which maps to chromosome 6p21. The deduced protein contains 417 amino acid residues. Southern blot analysis of human genomic DNAs showed a complex pattern of hybridizing fragments, 2 of which were non-X in origin. The results were interpreted as reflecting the existence of a small family of dispersed PGK or PGK-like genes.

Stroma-free hemoglobin cross-linked with reagents that mimic 2,3 diphosphoglycerate and transform stroma-free hemoglobin into a physiologically competent oxygen carrier which is retained in vivo for adequate periods of time and thus can be used in fluids for transporting oxygen; reagents for cross-linking stroma-free hemoglobin and method for cross-linking stroma-free hemoglobin.

PURPOSE: Phosphorus magnetic resonance spectroscopy ((31)P-MRS) affords unique insight into cardiac energetics but has a low intrinsic signal-to-noise ratio (SNR) in humans. Theory predicts an increased (31)P-MRS SNR at 7T, offering exciting possibilities to better investigate cardiac metabolism. We therefore compare the performance of human cardiac (31)P-MRS at 7T to 3T, and measure T1s for (31)P metabolites at 7T. METHODS: Matched (31)P-MRS data were acquired at 3T and 7T, on nine normal volunteers. A novel Look-Locker CSI acquisition and fitting approach was used to measure T1s on six normal volunteers. RESULTS: T1s in the heart at 7T were: phosphocreatine (PCr) 3.05 ± 0.41s, γ-ATP 1.82 ± 0.09s, α-ATP 1.39 ± 0.09s, β-ATP 1.02 ± 0.17s and 2,3-DPG (2,3-diphosphoglycerate) 3.05 ± 0.41s (N = 6). In the field comparison (N = 9), PCr SNR increased 2.8× at 7T relative to 3T, the Cramer-Ráo uncertainty (CRLB) in PCr concentration decreased 2.4×, the mean CRLB in PCr/ATP decreased 2.7× and the ...

The East Providence Lodge works with the Elks National Foundation by Earning a Gratitude Grant. The goal for this grant is set by the Grand Exalted Ruler. The ENF team members at the lodge met this …

In the direction shown, this enzyme is phosphorylated by 3-phosphoglyceroyl phosphate, to give phosphoenzyme and 3-phosphoglycerate. The latter is rephosphorylated by the enzyme to yield 2,3-bisphosphoglycerate, but this reaction is slowed by dissociation of 3-phosphoglycerate from the enzyme, which is therefore more active in the presence of added 3-phosphoglycerate. This enzyme also catalyses, slowly, the reaction of EC 5.4.2.11 [phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)] and EC 5.4.2.12 [phosphoglycerate mutase (2,3-diphosphoglycerate-independent ...

Sperm proteins are important for the sperm cell function in fertilization. Some of them are involved in the binding of sperm to the egg. We characterized the acrosomal sperm protein detected by a monoclonal antibody (MoAb) (Hs-8) that was prepared in our laboratory by immunization of BALB/c mice with human ejaculated sperms and we tested the possible role of this protein in the binding assay. Indirect immunofluorescence and immunogold labelling, gel electrophoresis, Western blotting and protein sequencing were used for Hs-8 antigen characterization. Functional analysis of GAPDHS from the sperm acrosome was performed in the boar model using sperm/zona pellucida binding assay. Monoclonal antibody Hs-8 is an anti-human sperm antibody that cross-reacts with the Hs-8-related protein in spermatozoa of other mammalian species (boar, mouse). In the immunofluorescence test, Hs-8 antibody recognized the protein localized in the acrosomal part of the sperm head and in the principal piece of the sperm flagellum. In

Authors: Freitas, J. , Braz-Nogueira, J. , Nogueira da Costa, J. , Martins e Silva, J. Article Type: Research Article Abstract: Twenty one ambulatory patients with essential hypertension (10 men, 11 women), 50.6±6.3 years old, had blood pressures of 167.5±17.1 mmHg for systolic and l06.2±9.9 mmHg for diastolic. Most of them were under treatment and target organ involvement was not important. Several parameters were calculated from a sample of venous blood: haemoglobin, haematocrit, P50 standard, carboxyhaemoglobin, red cell 2,3-diphosphoglycerate and erythrocyte filterability rate. As significant different from a group of control, it has been found a higher P50 standard (hypertensives 29.07±1.82 mmHg. vs. controls 27.74±0.86 mmHg, p , 0.05) and a lower filterablity rate (11.41±1.31 μ l.sec−l for hypertensives 15.80±0.83 …μ l.sec−l for controls, p , 0.001). The results suggest an augmentation of the rigidity of red blood cells that may have consequences on microcircultion and ...

SOUTH SAN FRANCISCO, Calif., Oct. 07, 2016 (GLOBE NEWSWIRE) - Global Blood Therapeutics, Inc. (GBT) (NASDAQ:GBT), a biopharmaceutical company developing novel therapeutics for the treatment of grievous blood-based disorders with significant unmet needs, today announced that an encore presentation of the GBT440-001 study data supporting the durability, safety and mechanism of action of GBT440 in sickle cell disease were presented today in an oral session at the Academy for Sickle Cell and Thalassemia (ASCAT) 10th Anniversary Conference in London.. "Hemoglobin oxygen affinity modulation is a very promising approach for modifying disease in SCD because it intervenes on the fundamental pathologic process- HbS polymerization. GBT440 is an exciting hemoglobin modifier in development because of excellent specificity and pharmaceutical properties resulting in both increased potency and an improved safety profile. Over three months of dosing, GBT440 has shown profound and durable reductions in hemolysis ...

Phosphofructokinase 2 (PFK2) or fructose bisphosphatase 2 (FBPase2), is an enzyme responsible for regulating the rates of glycolysis and gluconeogenesis in the human body. It is a homodimer of 55 kDa subunits arranged in a head-to-head fashion, with each polypeptide chain consisting of independent kinase and phosphatase domain. When Ser-32 of the bifunctional protein is phosphorylated, the negative charge causes the conformation change of the enzyme to favor the FBPase2 activity; otherwise, PFK2 activity is favored. The PFK2 domain is closely related to the superfamily of mononucleotide binding proteins including adenylate cyclase, whereas that of FBPase2 is related to a family of proteins that include phosphoglycerate mutases. The monomers of the bifunctional protein are clearly divided into two functional domains. The kinase domain is located on the N-terminal. It consists of a central six-stranded β sheet, with five parallel strands and an antiparallel edge strand, surrounded by seven α ...

Dromedary Jumping-slug, Hemphillia dromedarius, is an old-growth coniferous forest-dwelling slug endemic to southern British Columbia (B.C.) and western Washington, with unconfirmed records in northern Oregon. The species exists at the northernmost limits of its range in south western B.C. with a known Canadian range extent of approximately 4000 km2 confined to southern Vancouver Island. The species was located and confirmed in Canada in 1999. As of 2008, 15 locations have been defined for Dromedary Jumping-slug, with eight of these locations in protected areas. Additional undocumented localities likely exist, although the range extent is not likely to expand significantly. The Committee on the Status of Endangered Wildlife in Canada (COSEWIC) designated Dromedary Jumping-slug as Threatened in 2003, due to the fragmentation of its coniferous forest habitats and threats to the remaining habitats, mainly from forestry activities.

Middle East Respiratory Syndrome (MERS) is a zoonotic viral disease that can be transmitted from dromedaries to human beings. Up to December 2016, a total of 1841 cases of laboratory-confirmed MERS-CoV infection were reported to the World Health Organization, with an overall case fatality rate of 35% [1]. The current status of knowledge around MERS-CoV in dromedaries in Morocco still unknow. This article is a prospective study in dromedary herd during one year 2016 in the south of morocco. Faecal samples and nasal swabs of camels were analyzed for identification of viral sequences using specific polymerase chain reaction (PCR) methods.. ...

GAPDHS (the sperm-specific glyceraldehyde phosphate dehydrogenase, also known as GAPD2, GAPDS, HSD-35, or GAPDH-2, is a glycolytic enzyme that plays an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. It can be used as an intra-acrosomal marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction ...

Here again is a potential limiting factor for this pathway. The continuation of the reaction depends upon the availability of the oxidized form of the electron carrier, NAD+. Thus, NADH must be continuously oxidized back into NAD+ in order to keep this step going. If NAD+ is not available, the second half of glycolysis slows down or stops. If oxygen is available in the system, the NADH will be oxidized readily, though indirectly, and the high-energy electrons from the hydrogen released in this process will be used to produce ATP. In an environment without oxygen, an alternate pathway (fermentation) can provide the oxidation of NADH to NAD+.. Step 7. In the seventh step, catalyzed by phosphoglycerate kinase (an enzyme named for the reverse reaction), 1,3-bisphosphoglycerate donates a high-energy phosphate to ADP, forming one molecule of ATP. (This is an example of substrate-level phosphorylation.) A carbonyl group on the 1,3-bisphosphoglycerate is oxidized to a carboxyl group, and ...

Of the combinations tried, the admixture of methylene blue, progesterone, adenine and inosine maintained 2,3-diphosphoglycerate and adenosine triphosphate at high levels in citrate-phosphate-dextrose blood for a storage period of 6 weeks, about equal to those of the control values on the day of collection. (Author)(*BLOOD

HEADER ISOMERASE 19-JUL-00 1E59 TITLE E.COLI COFACTOR-DEPENDENT PHOSPHOGLYCERATE MUTASE COMPLEXED TITLE 2 WITH VANADATE COMPND MOL_ID: 1; COMPND 2 MOLECULE: PHOSPHOGLYCERATE MUTASE; COMPND 3 CHAIN: A; COMPND 4 EC: 5.4.2.1; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; SOURCE 3 ORGANISM_TAXID: 83333; SOURCE 4 STRAIN: K12; SOURCE 5 GENE: PGM1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PET3A KEYWDS INHIBITOR, VANDATE, GLYCOLYSIS AND GLUCONEOGENESIS, KEYWDS 2 PHOSPHOGLYCERATE MUTASE, ISOMERASE EXPDTA X-RAY DIFFRACTION AUTHOR C.S.BOND,W.N.HUNTER REVDAT 3 24-FEB-09 1E59 1 VERSN REVDAT 2 15-MAR-02 1E59 1 JRNL REVDAT 1 05-FEB-02 1E59 0 JRNL AUTH C.S.BOND,M.WHITE,W.N.HUNTER JRNL TITL MECHANISTIC IMPLICATIONS FOR ESCHERICHIA COLI JRNL TITL 2 COFACTOR-DEPENDENT PHOSPHOGLYCERATE MUTASE BASED JRNL TITL 3 ON THE HIGH-RESOLUTION CRYSTAL ...

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Isolation and characterization of cytochrome oxidase protein subunits from mammalian mitochondria and two micro-organisms (Thermophilic bacteria P53 and Thiobacillus ferrioxidans). Our goal is to compare the common protein subunits and their individual functions. The procedures to identify these subunits are by Elisa and Western blot analyses using polyclonal and monoclonal antibodies previously prepared against the mammalian species. So far, we have found that the three largest subunits are common in all cytochrome oxidase samples, while little information is known about the smaller subunits. Our eventual aim is to understand the detailed enzyme mechanism of this important terminal member of electron transport chain and its contribution to energy transduction ...

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Hence blood with high carbon dioxide levels is also lower in pH (more acidic). Hemoglobin can bind protons and carbon dioxide which causes a conformational change in the protein and facilitates the release of oxygen. Protons bind at various places along the protein, and carbon dioxide binds at the alpha-amino group forming carbamate. Conversely, when the carbon dioxide levels in the blood decrease (i.e., in the lung capillaries), carbon dioxide and protons are released from hemoglobin, increasing the oxygen affinity of the protein. This control of hemoglobins affinity for oxygen by the binding and release of carbon dioxide and acid, is known as the Bohr effect. The binding of oxygen is affected by molecules such as carbon monoxide (CO) (for example from tobacco smoking, cars and furnaces). CO competes with oxygen at the heme binding site. Hemoglobin binding affinity for CO is 200 times greater than its affinity for oxygen, meaning that small amounts of CO dramatically reduce hemoglobins ...

Background: Sickle cell disease (SCD) is a genetic disorder in which deoxygenation produces polymerization of mutated hemoglobin S (HbS) and triggers the downstream effects of red blood cell deformation (sickling), hemolysis, vaso-occlusion and inflammation. Injury from SCD starts in infancy and accumulates over a lifetime causing significant end-organ damage and ischemic tissue injury, leading to fatigue, pain (vaso-occlusive crisis) and other clinical complications that are under-recognized, under-treated, and associated with early death. GBT440 is an oral, once-daily therapy that modulates hemoglobin affinity for oxygen, thereby inhibiting hemoglobin polymerization. GBT440-007 is a Phase 2a study designed to assess the safety, pharmacokinetics (PK) and efficacy of GBT440 in pediatric SCD patients (HbSS or HbSβ0 thalassemia). This abstract reports the first evaluation of multiple doses of GBT440 in adolescents (12 to 17 years) with SCD. Methods: This ongoing study is being conducted in 2 ...

HbF has greater attraction to O2 than Hb low % O2 by time blood reaches placenta fetal Hb must be able to bind O2 with greater attraction than maternal Hb Both mother and fetus share a common blood supply. In particular, the fetuss blood supply is delivered via the umbilical vein from the placenta, which is anchored to the wall of the mothers uterus. As blood courses through the mother, oxygen is delivered to capillary beds for gas exchange, and by the time blood reaches the capillaries of the placenta, its oxygen saturation has decreased considerably. In order to recover enough oxygen to sustain itself, the fetus must be able to bind oxygen with a greater affinity than the mother. Fetal hemoglobins affinity for oxygen is substantially greater than that of adult hemoglobin. Notably, the P50 value for fetal hemoglobin (i.e., the partial pressure of oxygen at which the protein is 50% saturated; lower values indicate greater affinity) is roughly 19 mmHg, whereas adult hemoglobin has a value of ...

Middle Eastern respiratory syndrome coronavirus (MERS-CoV), first identified in the fall of 2012 in a Saudi Arabian patient, has since infected over 180 individuals, causing 77 deaths. Antibodies to the virus and the viral genome have been found in dromedary camels in Jordan and Saudi Arabia, implicating those animals as the source of human infections. A new study reveals that the virus has infected camels throughout Saudi Arabia since at least 1992.. Serum, blood, and rectal and nasal swabs were collected from dromedary camels in November-December 2013 from southwestern, western, northwestern, eastern, and central regions of the Kingdom of Saudi Arabia. Of 203 serum samples, 150 (74%) were found to contain antibodies to MERS-CoV. The number of seropositive animals varied from 5% to 95% depending on location and the age of the animals (in general, seropositivity was higher in adult camels compared with young camels). Antibodies against MERS-CoV were also detected in archived serum samples from ...

The researchers examined nasal samples collected during a countrywide survey of dromedary camels and selected samples from two animals with the highest viral load. They cultured and obtained complete genomic sequence from both animals as well as virus in nasal samples from several other camels.. The mathematical means of all genetic sequences (the consensus genomic sequences) were consistent with viruses found in human cases; however, samples from camels contained more than one virus genotype. Over a period of 48 hours of culture in primate cells, the genomic variation of viruses narrowed, mirroring the lower sequence diversity reported in MERS-CoV found in humans.. "The finding of infectious virus strengthens the argument that dromedary camels are reservoirs for MERS-CoV," says first author Thomas Briese, PhD, associate director of the Center for Infection and Immunity and associate professor of Epidemiology at the Mailman School. "The narrow range of MERS viruses in humans and a very broad ...

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Reactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge.

Expression of CDC42BPG (DMPK2, HSMDPKIN, kappa-200, MRCKgamma) in lung tissue. Antibody staining with HPA027382 and HPA061836 in immunohistochemistry.

Expression of CDC42BPG (DMPK2, HSMDPKIN, kappa-200, MRCKgamma) in fallopian tube tissue. Antibody staining with HPA027382 and HPA061836 in immunohistochemistry.

Glyceraldehyde-3-phosphate dehydrogenase (NADP+)(phosphorylating); Involved in the photosynthetic carbon assimilation. Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phos [...] (337 aa ...

The effect of reducing hemoglobin affinity for O2 on fetal oxygenation was assessed in seven fetal lambs in which fetal blood was almost completely replaced by maternal blood 2-3 days postoperatively. Measurements of fetal blood gases and organ blood flow (radionuclide-labeled microsphere technique) were obtained before and 1 h after the exchange transfusion. Umbilical venous blood PO2 increased from 29 +/- 5 to 35 +/- 6 (SD) Torr (P less than 0.001) but hemoglobin O2 saturation decreased from 78.2 +/- 10.3 to 39.8 +/- 8.8% (P less than 0.001), resulting in a 46% decrease in umbilical venous blood O2 content. Since umbilical-placental blood flow also decreased (P less than 0.002), O2 delivery to the fetus decreased by 64% (P less than 0.002). Although O2 extraction increased from 32.5 +/- 6.8 to 50.9 +/- 9.0% (P less than 0.002), fetal O2 consumption fell from 7.28 +/- 1.97 to 4.10 +/- 1.20 ml X min-1 X kg-1 (P less than 0.02), and metabolic acidemia developed. No significant change in fetal ...

Physiology Test Question - A higher numerical value of oxygen (O2) P50 indicates a higher hemoglobin affinity for O2. Note: O2 P50 is the oxygen partial pressure (PO2) at which 50% of hemoglobin molecules are saturated with O2.

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... Offering free WiFi and free onsite parking, Cascades Motor lodge is located in Pakuranga, Auckland. Surrounded by lovely gardens, all accommodation includes cooking facilities.

2016 Wildwood Lodge DLX 402QBQ available at Greeneway RV Sales and Service. WILDWOOD LODGE DLX Seamless Walk on RoofTriple Sealed SlideoutsIn-Floor Ducted HeatDucted Central A/CWater Heater By-PassDSI Water HeaterFlush-Floor Slide RoomsSystems Monitor PanelStain Resistant Carpet DVD/CD/AM/FM MP3Surround SoundHigh Rise Kitchen FaucetRange w/OvenRefrigeratorMicrowaveThermoform CountertopsFoot Flush Toilet

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In order to determine whether daily exposure to methylene chloride (75092) vapors affects hemoglobin affinity for oxygen and/or pulmonary function, four healthy young males aged 22 to 24 years were exposed for 7-1/2 hours per day for 26 days in an environmental chamber over 6 consecutive weeks to various concentrations (0 to 50ppm) of methylene-chloride vapor. Effects of the vapor on pulmonary air

p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...

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The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015 ...

GT:ID BAD56223.1 GT:GENE BAD56223.1 GT:PRODUCT putative phosphoglycerate mutase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 1542838..1543497 GB:FROM 1542838 GB:TO 1543497 GB:DIRECTION + GB:PRODUCT putative phosphoglycerate mutase GB:PROTEIN_ID BAD56223.1 LENGTH 219 SQ:AASEQ MSKYAGVRTLILLRHGQTEWNATDRMQGQIDTDLTELGRRQAKEAARELVSRNAIAIVSSDLRRAHDTALALAEHTDVPVALDPRLRETHLGDWQGLTHLEVDADYPGARVAWRLDATYRPPGGESKLEVGARALPVVRELYNERQDWPGRTIILVAHGGLIAALTAALLELPPQNWPALGGLANTSWVQLSSHGPGIDQPGWRLDVWNAAAKVAPDVL GT:EXON 1,1-219:0, BL:SWS:NREP 1 BL:SWS:REP 8-,136,GPMA_NITWN,4e-19,42.6,129/207, PROS 12-,21,PS00175,PG_MUTASE,PDOC00158, SEG 157-,172,ahggliaaltaallel, BL:PDB:NREP 1 BL:PDB:REP 9-,156,1h2eA,2e-22,40.0,145/207, RP:PDB:NREP 1 RP:PDB:REP 8-,209,1ebbA,8e-30,32.0,194/202, RP:PFM:NREP 1 RP:PFM:REP 10-,156,PF00300,2e-23,45.8,144/158,PGAM, HM:PFM:NREP 1 HM:PFM:REP 9-,165,PF00300,3.7e-45,40.0,155/158,PGAM, RP:SCP:NREP 1 RP:SCP:REP 8-,209,1ebbA,3e-30,32.0,194/202,c.60.1.1, HM:SCP:REP ...

This discovery led to the testing of other combinations. It is now known that many pairs of organic phosphate insecticides are highly dangerous, the toxicity being stepped up or "potentiated" through the combined action. Potentiation seems to take place when one compound destroys the liver enzyme responsible for detoxifying the other. The two need not be given simultaneously. The hazard exists not only for the man who may spray this week with one insecticide and next week with another; it exists also for the consumer of sprayed products. The common salad bowl may easily present a combination of organic phosphate insecticides. Residues well within the legally accessible limits may interact.. The full scope of the dangerous interaction of chemicals is as yet little known, but disturbing findings now come regularly from scientific laboratories. Among these is the discovery that the toxicity of an organic phosphate can be increased by a second agent that is not necessarily an insecticide. For ...

DPG(D) Chemical Name:Diphenyl guanidine Structure: Molecular Formula:C13H13N3 Molecular Weight:211.27 CAS NO:102-06-7 Specification: Item Powder Oiled powder Granule Appearance Gray-white powder(granule) Initial M.P.οC≥ 145.0 145.0 145.0 Loss on drying%≤ 0.30 0.40 0.30 Ash%≤ 0.30 0.40 0.30 Residues on150μm sieve, %≤ 0.10 0.10 / Residues on63μm), %≤ 0.50 0.50 / Additive, % / 0.0-2.0 / Granule Diameter, mm / / 1.50 Properties:Grayish-white powder(granule)No taste, no poison. Densiy is 1.08--1.19. Soluble in acetone, ethyl acetate, benzene, alcohol, slightly soluble in CCl4; Insoluble in water and gasoline. Application:Used as a secondary accelerator with thiazoles and sulphenamides in NR and SBR compounds. Exhibits better storage stability compared to thiuram and dithiocarbamates but is not so active. DPG can be used in latex as secondary gelling agent (foam stabilizer) in the silico-flouride foam process. Packaging:25kg bag. Storage:Keep container tightly closed in a cool, ...

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Cultivated cassava (Manihot esculenta) has a higher rate of photosynthesis than is usual for C3 plants and photosynthesis is not light saturated. For these reasons it has been suggested that cultivated cassava could be derived from wild species possessing C4 photosynthesis. The natural abundance of 13C and activities of phosphoenolpyruvate carboxylase and phosphoglycolate phosphatase were measured in leaves of 20 wild cassava species to test this hypothesis. All the species studied, including M. flabellifolia the potential wild progenitor of cultivated cassava, clearly exhibited C3 not C4 characteristics ...

1EQJ: Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate.

Pgam2 - Pgam2 (Myc-DDK-tagged ORF) - Rat phosphoglycerate mutase 2 (muscle) (Pgam2), (10 ug) available for purchase from OriGene - Your Gene Company.

DROMEDARY COOK BOOK SPECIAL COLLECTIONS THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES ,E take this opportunity of presenting to the American Housewife a col- lection of recipes which have to do with a class of food products but little known. The dietetic value of such fruits as dates, figs, currants, etc., is a high one and these fruits should appear on our tables at least once a day. The brands mentioned are all standard and some of them have been on the market for the last twenty-five years. The recipes are all based on the use of the best grades of the various products and these brands stand for the highest quality as well as for absolute cleanliness of pack. Any good fruit dealer or grocer can supply them. The recipes which we have published in this little book have been selected from a large number submitted in our prize contest held in 1910. They have been thoroughly tested and we hope will meet with the approval of all who have occasion to use them. THE HILLS BROTHERS COMPANY ...

Shop Oman, Wadi darbat, dromedaries pasturing in the Jigsaw Puzzle created by DanitaDelimont. Personalize it with photos & text or purchase as is!

Die Dromedary Bags von MSR sind expeditionstaugliche Bombertaschen, die den härtesten Bedingungen und hohen Anforderungen standhalten.

gpmA; highly similar to 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp,A6T6I3); K01834 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] ...

1E58: High Resolution Structure of the Phosphohistidine-Activated Form of Escherichia Coli Cofactor-Dependent Phosphoglycerate Mutase.

Semantic Scholar extracted view of Studies on the heterotropic interaction of hemoglobin. II. Role of beta-146 and beta-2 histidines in the alkaline Bohr effect. by Masato Ohe et al.

This nursing Best Practice Guideline (BPG) is intended to replace the RNAO BPG Client Centred Care (2002) and its supplement (2006). It is to be used by nurses and other members of the interprofessional health-care team ...

Bi alîkariya ava mîdeyê, ku bi asîd pêkhatiye û bi alîkariya enzîman (li livikên -tosbiyên- bedenê mirovan da tên çêkirin û ji bo hezmê u pir tiştên din hewce ne) xwarin tê hezimkirin. Mîde kareki wek ambar pêktîne û xwarinê perçe perçe dide rûviya danzdeh gire, him ji destpêka hezma xwarine dike. Dawiya wê rûviya zirav tê, ku 3 metre dirêjiya xwe heye. Dawî rûviya zirav xwarin tê û digiheje rûviya stûr. Rûviya stûr nêzîkî 1,5 metre dirêj e.. Nava gedekê bi giştî gelek tirş e. Rêje ya tirşatî ya gedekê anko pH a gedekê, di navbera 1 heta 4ê da ye. Xaneyên serekî yên gedekê maddeyekî bi navê pêpsînosênê dirêjin nav gedekê ko bi tirşê hîdroklorîk dibit pêpsîn. Gedek rojane 2 heta 4 lîtreyên şîrê gedekê dirêjit.. ...

We have Oracle 9.2.0.4 running on Red Hat AS 2.1. We are considering upgrading the operating system to Red Hat AS 3.0 or Red Hat AS 4.0. Oracle 9.2.0.4 appears to be certified on Red Hat AS 3.0 but Im not sure if there are any steps that need to be done to protect Oracle 9.2.0.4 and have it work on Red Hat AS 3.0? Also, is it true that Oracle 9.2.0.4 is not certified on Red Hat AS 4.0?

K01834 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] , (GenBank) gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate ...

Did you know that scientists have successfully crossbred camels with llamas a couple of times? It only works when the male is a Dromedary (artificial insemination is required), but since both species have 74 chromosomes, there is potential for the Cama (as the hybrid is known) to be fertile, thus spawning a new work animal (they already have half Dromedary / half Bactrians called Bukhts). But, alas, the cama inherited the poor temperament of both parents. Lovely. ...

HELIX DETERMINATION METHOD: PROCHECK, WITH IDENTIFICATION CORRESPONDING TO 2.0A L. MESENTEROIDES STRUCTURE, 1DPG. HELIX_ID: A,BEND AT K21 IS CONSEQUENCE OF CONSERVED P24. HELIX_ID: D,THE FIRST TURN IS 3_10 (CLASS 5). HELIX_ID: F,THE FIRST 2 TURNS ARE 3_10 (CLASS 5). HELIX_ID: H,G231 BRIDGES H & I' SO IS NOT HELICAL. HELIX_ID: I',PART OF HELIX I IN 1DPG. RESIDUES 235-239 DISTORTED BY SIDECHAIN INTERACTION OF N239 WITH D235 ...

dpG antibodies were fractionated on a cellulose-double-stranded DNA column. The flow-through fraction bound denatured DNA but not double-stranded DNA (dsDNA). The dpG-eluted fraction bound dsDNA preferentially. The results show that proteins can recognise dpG in DNA by different mechanisms, some involving DNA unwinding.. ...

The Chicago Bulls announced today the team has exercised its fourth-year option for the 2012-13 season for forward Taj Gibson.. In two seasons with Chicago, Gibson (6-9, 225) has appeared in 162 games (89 starts) and averaged 8.0 ppg, 6.6 rpg, and 1.30 bpg in 24.4 mpg; he has shot .485 from the field and .659 from the line. The Bulls selected Gibson in the first round (26th overall) in the 2009 NBA Draft.. InsideHoops.com editor says: This was an easy call for the Bulls. Gibson is a very solid backup forward who is capable of starting for stretches.. ...

Mitsubishi Motors Corporation, with cooperation from the Aichi Industrial Technology Institute (Kariya, Aichi Prefecture), has developed an automotive interior material which uses a plant-based resin, polybutylene succinate (PBS), combined with bamboo fiber

Gaddafis got the hump : Benghazi The Libyan Camel Racing Association has petitioned Colonel Gaddafi about ritual interference to his prized dromedary Apparently the mad old despot has been overmilking his favorite beastie to make camel cheese and butter But an ac

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Hemoglobin below age appropriate norms (Reduction in O2 transport to tissues -, tissue hypoxia -, compensation (increased CO, increased 2,3DPG)). Pathophysiology. ...

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