2,3-Diketogulonic Acid: Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Drug Information Services: Services providing pharmaceutic and therapeutic drug information and consultation.National Library of Medicine (U.S.): An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.Counterfeit Drugs: Drugs manufactured and sold with the intent to misrepresent its origin, authenticity, chemical composition, and or efficacy. Counterfeit drugs may contain inappropriate quantities of ingredients not listed on the label or package. In order to further deceive the consumer, the packaging, container, or labeling, may be inaccurate, incorrect, or fake.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Government Agencies: Administrative units of government responsible for policy making and management of governmental activities.MEDLARS: A computerized biomedical bibliographic storage and retrieval system operated by the NATIONAL LIBRARY OF MEDICINE. MEDLARS stands for Medical Literature Analysis and Retrieval System, which was first introduced in 1964 and evolved into an online system in 1971 called MEDLINE (MEDLARS Online). As other online databases were developed, MEDLARS became the name of the entire NLM information system while MEDLINE became the name of the premier database. MEDLARS was used to produce the former printed Cumulated Index Medicus, and the printed monthly Index Medicus, until that publication ceased in December 2004.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Drug Labeling: Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.Pharmacists: Those persons legally qualified by education and training to engage in the practice of pharmacy.United StatesDisease Transmission, Infectious: The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).Metals: Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)Composite Resins: Synthetic resins, containing an inert filler, that are widely used in dentistry.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Electric Organ: In about 250 species of electric fishes, modified muscle fibers forming disklike multinucleate plates arranged in stacks like batteries in series and embedded in a gelatinous matrix. A large torpedo ray may have half a million plates. Muscles in different parts of the body may be modified, i.e., the trunk and tail in the electric eel, the hyobranchial apparatus in the electric ray, and extrinsic eye muscles in the stargazers. Powerful electric organs emit pulses in brief bursts several times a second. They serve to stun prey and ward off predators. A large torpedo ray can produce of shock of more than 200 volts, capable of stunning a human. (Storer et al., General Zoology, 6th ed, p672)Polyurethanes: A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.Dental Materials: Materials used in the production of dental bases, restorations, impressions, prostheses, etc.Methacrylates: Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.Polymethacrylic Acids: Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.Gas Chromatography-Mass Spectrometry: A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.Mass Spectrometry: An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.Chromatography, Gas: Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Chromatography, Liquid: Chromatographic techniques in which the mobile phase is a liquid.Volatile Organic Compounds: Organic compounds that have a relatively high VAPOR PRESSURE at room temperature.Solid Phase Microextraction: A solventless sample preparation method, invented in 1989, that uses a fused silica fiber which is coated with a stationary phase. It is used for sample cleanup before using other analytical methods.Metabolomics: The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.Tandem Mass Spectrometry: A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.Mythology: A body of stories, the origins of which may be unknown or forgotten, that serve to explain practices, beliefs, institutions or natural phenomena. Mythology includes legends and folk tales. It may refer to classical mythology or to a body of modern thought and modern life. (From Webster's 1st ed)Burns, ChemicalNorth CarolinaDiphtheria Toxin: An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.Diphtheria: A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.Syringes: Instruments used for injecting or withdrawing fluids. (Stedman, 25th ed)Aircraft: A weight-carrying structure for navigation of the air that is supported either by its own buoyancy or by the dynamic action of the air against its surfaces. (Webster, 1973)Pesticides: Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.Eye Burns: Injury to any part of the eye by extreme heat, chemical agents, or ultraviolet radiation.Pantothenic Acid: A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.Riboflavin: Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as FLAVIN MONONUCLEOTIDE and FLAVIN-ADENINE DINUCLEOTIDE.Thiamine: 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.Vitamin B Complex: A group of water-soluble vitamins, some of which are COENZYMES.Niacinamide: An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.Cereals: Seeds from grasses (POACEAE) which are important in the diet.Vitamins: Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.Vitamin A: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.History of NursingBehavioral Medicine: The interdisciplinary field concerned with the development and integration of behavioral and biomedical science, knowledge, and techniques relevant to health and illness and the application of this knowledge and these techniques to prevention, diagnosis, treatment, and rehabilitation.Protein-Energy Malnutrition: The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.Kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning "displaced child". Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)Adolescent Medicine: A branch of medicine pertaining to the diagnosis and treatment of diseases occurring during the period of ADOLESCENCE.Perinatology: The branch of medicine dealing with the fetus and infant during the perinatal period. The perinatal period begins with the twenty-eighth week of gestation and ends twenty-eight days after birth. (From Dorland, 27th ed)Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Access to Information: Individual's rights to obtain and use information collected or generated by others.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Stevia: A plant genus of the family ASTERACEAE. Members contain stevioside and other sweet diterpene glycosides. The leaf is used for sweetening (SWEETENING AGENTS).Diterpenes, Kaurane: A group of DITERPENES cyclized into four rings.BrazilGlucosidesGlycosides: Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)Diterpenes: Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate.
*  List of MeSH codes (D02)
... edetic acid MeSH D02.241.081.038.455 --- egtazic acid MeSH D02.241.081.038.581 --- iodoacetic acid MeSH D02.241.081.038.581.400 ... muramic acids MeSH D02.241.081.844.562 --- neuraminic acids MeSH D02.241.081.844.562.668 --- sialic acids MeSH D02.241.081.844. ... quinic acid MeSH D02.241.511.852 --- shikimic acid MeSH D02.241.511.902 --- sugar acids MeSH D02.241.511.902.107 --- ascorbic ... muramic acids MeSH D02.241.511.902.562 --- neuraminic acids MeSH D02.241.511.902.562.668 --- sialic acids MeSH D02.241.511.902. ...
*  Ascorbic acid (molecular aspects)
... ascorbic acid will undergo further oxidative decomposition to various products including diketogulonic acid, xylonic acid, ... a diastereomer of ascorbic acid. Mineral ascorbates: salts of ascorbic acid Acids in wine Safety (MSDS) data for ascorbic acid ... to produce ascorbic acid. L-Ascorbic acid has a negative feedback on L-galactose dehydrogenase in spinach. Ascorbic acid efflux ... The biosynthesis of ascorbic acid starts with the formation of UDP-glucuronic acid. UDP-glucuronic acid is formed when UDP- ...
What does 2,3-diketogulonic acid mean?  What does 2,3-diketogulonic acid mean?
Definition of 2,3-diketogulonic acid in the Definitions.net dictionary. Meaning of 2,3-diketogulonic acid. What does 2,3- ... diketogulonic acid mean? Information and translations of 2,3-diketogulonic acid in the most comprehensive dictionary ... Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID. ... Discuss these 2,3-diketogulonic acid definitions with the community:. Word of the Day. Would you like us to send you a FREE new ...
more infohttp://www.definitions.net/definition/2,3-diketogulonic%20acid
Drug Information Portal - U.S. National Library of Medicine - Quick Access to Quality Drug Information  Drug Information Portal - U.S. National Library of Medicine - Quick Access to Quality Drug Information
Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID. ... 2,3-Diketogulonic acid View Synonyms. View Structure. Description:. ...
more infohttps://druginfo.nlm.nih.gov/drugportal/rn/3409-57-2
Vitamin C - Ruminants - Compendium - DSM  Vitamin C - Ruminants - Compendium - DSM
Dehydroascorbic acid is irreversibly oxidized to the inactive diketogulonic acid. Since this change takes place readily, ... A 0.5% aqueous solution of ascorbic acid is strongly acid, with a pH of 3. Ascorbic acid is more stable in an acidic than an ... L-ascorbic acid is the most important of several compounds that have vitamin C activity. Ascorbic acid is commercially ... The L-isomer of ascorbic acid is biologically active, while the D-isomer is not. In biological systems, L-ascorbic acid can be ...
more infohttps://www.dsm.com/markets/anh/en_US/Compendium/ruminants/vitamin_C.html
List of MeSH codes (D02) - Wikipedia  List of MeSH codes (D02) - Wikipedia
... edetic acid MeSH D02.241.081.038.455 --- egtazic acid MeSH D02.241.081.038.581 --- iodoacetic acid MeSH D02.241.081.038.581.400 ... muramic acids MeSH D02.241.081.844.562 --- neuraminic acids MeSH D02.241.081.844.562.668 --- sialic acids MeSH D02.241.081.844. ... quinic acid MeSH D02.241.511.852 --- shikimic acid MeSH D02.241.511.902 --- sugar acids MeSH D02.241.511.902.107 --- ascorbic ... muramic acids MeSH D02.241.511.902.562 --- neuraminic acids MeSH D02.241.511.902.562.668 --- sialic acids MeSH D02.241.511.902. ...
more infohttps://en.wikipedia.org/wiki/List_of_MeSH_codes_(D02)
Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic...  Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic...
2006) Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products. J Nutr 136: ... 2000) Metabolic engineering of an alternative pathway for ascorbic acid biosynthesis in plants. Mol Breeding 6:73-78. ... 2006) Progress in manipulating ascorbic acid biosynthesis and accumulation in plants. Physiol Plant 126:343-355. ... A Single Amino Acid Substitution in an ORANGE Protein Promotes Carotenoid Overaccumulation in Arabidopsis ...
more infohttp://www.pnas.org/content/106/19/7762?ijkey=8d11ef1f8063f648d6e5c2e7d5e669da96ff22a0&keytype2=tf_ipsecsha
Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic...  Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic...
2006) Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products. J Nutr 136: ... 2000) Metabolic engineering of an alternative pathway for ascorbic acid biosynthesis in plants. Mol Breeding 6:73-78. ... 2006) Progress in manipulating ascorbic acid biosynthesis and accumulation in plants. Physiol Plant 126:343-355. ... A Single Amino Acid Substitution in an ORANGE Protein Promotes Carotenoid Overaccumulation in Arabidopsis ...
more infohttps://www.pnas.org/content/106/19/7762.full
2016; 1(2):141-156 | ss site title  2016; 1(2):141-156 | ss site title
Mitochondrial recycling of ascorbic acid from dehydroascorbic acid: dependence on the electron transport chain. Arch Biochem ... Characterization of ascorbic acid transport by adrenomedullary chromaffin cells. Evidence for Na+-dependent co-transport. J ... Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to ... Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation. Basic Clin ...
more infohttps://www.aimsci.com/ros/html/?page_id=180
The Medicinal Value and the Numerous Sources of Vitamin C - A Review  The Medicinal Value and the Numerous Sources of Vitamin C - A Review
VC: Vitamin c; L-AA: L-ascorbic acid; DHA: L-dehydroascorbic acid; GLO: l-Gulonolactone Oxidase Gene; LDL: Low Density ... Kyrtopoulos SA (1987) Ascorbic acid and the formation of N-nitroso compounds: possible role of ascorbic acid in cancer ... A study in USA stated that after supplementation with VC there was a decrease of 45% in level of uric acid with intake of 1500 ... Ohno S, Ohno Y, Suzuki N, Soma G, Inoue, M (2009) High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with ...
more infohttps://medcraveonline.com/JNHFE/JNHFE-02-00061
Acyclic Acids (Ethanoic Acids)  < Carboxylic Acids  << Organic Compounds (Organic Chemicals)  <<< Compounds, Elements & more  @...  Acyclic Acids (Ethanoic Acids) < Carboxylic Acids << Organic Compounds (Organic Chemicals) <<< Compounds, Elements & more @...
Acyclic Acids are Carboxylic acids, a 2 carbon straight-chain saturated carboxylic acid, that has an open-chain molecular ... Acyclic Acids (Ethanoic Acids). "Acyclic Acids (Ethanoic Acids)" Acyclic Acid. In organic chemistry, Acyclic Acids (Ethanoic ... Uronic Acids *Glucuronates *Glucuronic Acid *Glucuronides *Hexuronic Acids *Iduronic Acid *Tricarboxylic Acids *Aconitic Acid * ... "Imino Acids (Secondary Amino Acids)" Secondary Amino Acids. In protein science, an Imino Acid (Secondary Amino Acid) is a ...
more infohttp://wellnessadvocate.com/?uid=84521
COMPOSITE MATERIAL, ELECTRIC CONTACT ELECTRODE, ELECTRIC CONTACT FILM,     CONDUCTIVE FILLER, ELECTRIC CONTACT STRUCTURE USING...  COMPOSITE MATERIAL, ELECTRIC CONTACT ELECTRODE, ELECTRIC CONTACT FILM, CONDUCTIVE FILLER, ELECTRIC CONTACT STRUCTURE USING...
... and reductic acid, which are decomposition products of L-ascorbic acid or D-araboascorbic acid. 16. A manufacturing method of ... 0059] The reason is in a feature of decomposition products of L-ascorbic acid. L-ascorbic acid is decomposed in order of ... For example, the reducing agent may include at least one of L-ascorbic acid, D-araboascorbic acid, the acetaldehyde 2,4-dinitro ... 0060] L-ascorbic acid, which is starting material, and reductic acid, which is a decomposition product, have keto-enediol ...
more infohttp://www.patentsencyclopedia.com/app/20130081855
Subject: dehydroascorbic acid / Text Availability: Full Text - PubAg Search Results  Subject: 'dehydroascorbic acid' / Text Availability: Full Text - PubAg Search Results
dehydroascorbic acid, etc ; ascorbic acid; chemical reactions; chemical bonding; glucobrassicin; cresols; coumaric acids; ... organic acids, ascorbic acid (AA), dehydroascorbic acid, and 2,3-diketogulonic acid were used to estimate the extent of NEB ... You searched for: Subject 'dehydroascorbic acid' Remove constraint Subject: 'dehydroascorbic acid' Text Availability Full Text ... dehydroascorbic acid, etc ; Nicotiana tabacum; cell suspension culture; cell cycle; ascorbic acid; oxidation; redox potential; ...
more infohttps://pubag.nal.usda.gov/?f%5Btext_availability%5D%5B%5D=Full+Text&q=%22dehydroascorbic+acid%22&search_field=subject&sort=relevance
Subject: syrups / Text Availability: Full Text - PubAg Search Results  Subject: 'syrups' / Text Availability: Full Text - PubAg Search Results
... organic acids, ascorbic acid (AA), dehydroascorbic acid, and 2,3-diketogulonic acid were used to estimate the extent of NEB ... Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino acids with protein anabolic properties ... maple syrup urine disease, etc ; amino acid composition; amino acid metabolism; case studies; cesarean section; compliance; ... rice syrup, etc ; Lactobacillus plantarum; beverages; cell viability; fermentation; lactic acid; lactic acid bacteria; ...
more infohttps://pubag.nal.usda.gov/?f%5Btext_availability%5D%5B%5D=Full+Text&q=%22syrups%22&search_field=subject
US5212096A - Gas chromatography/mass spectrometry determination of ascorbate and oxidation products thereof 
        - Google...  US5212096A - Gas chromatography/mass spectrometry determination of ascorbate and oxidation products thereof - Google...
The ions represent dehydroascorbate (345), diketogu-lonic acid (415) and the proposed dicarboxylic acid species (505) Exposure ... diketogulonic acids and the C6 -dicarboxylic acid species. As shown in FIG. 4A, the relative amount of DHA (345 to 575 ratio) ... the diketogulonic acid and ketotrihydroxyadipic acid isomers illustrated herein, is a sensitive indicator of redox potential ... These are consistent with diketogulonic acid (triangles) and dicarboxylic acid (diamond).. DETAILED DESCRIPTION OF THE ...
more infohttps://patents.google.com/patent/US5212096?oq=flatulence
Multimeric oxidoreductases - Danisco US Inc.  Multimeric oxidoreductases - Danisco US Inc.
Examples of sugar acids include aldonic acids, uronic acids and aldonic acids. More specifically, sorbitol, gluconic acid, ... D-araboascorbic acid (erythorbic acid), which shows vitamin C activity, L-araboascorbic acid, and D-xyloascorbic acid. ... gluconic acid and other AsA intermediates, succinic acid, citric acid, lactic acid. ... dehydroascorbic acid, erythorbic acid and mannonic acid. In some preferred embodiments the carbon substrate is a hexose or a ...
more infohttp://www.freepatentsonline.com/8975048.html
253. Diethyl pyrocarbonate (WHO Food Additives Series 4)  253. Diethyl pyrocarbonate (WHO Food Additives Series 4)
... ascorbic acid, dehydroascorbic acid, diketogulonic acid and furfural (Anon., 1965). In the reaction products resulting from ... The following substances were investigated in this respect; tricarbethoxy gallic acid, dicarbethoxy chlorogenic acid, mono- and ... hydroxy acids, ascorbic acid and ethanol. The predominant reaction, however, remains the normal hydrolysis to CO2 and ethanol. ... The reaction may also theoretically occur at acid pH where NH4+/NH3 equilibria exists. Model experiments using high levels of ...
more infohttp://www.inchem.org/documents/jecfa/jecmono/v004je06.htm
1) Sydney, Australia JUNE % PDF  1) Sydney, Australia JUNE % PDF
VOLUME NUMBER 2 JUNE % 958 Published by the Division of Food Preservation and Transport Commonwealth Scientific and Industrial ... diketogulonic acid). At high ph further degradation occurs. In the absence of oxygen ascorbic acid undergoes a slow anaerobic ... Prelab 6: Carboxylic Acids The Structure of Carboxylic Acids Prelab 6: Carboxylic Acids Carboxylic acids contain a carboxyl ... Carboxylic Acids, Esters and Acyl Chlorides R hemistry A 432 arboxylic Acids, Esters and Acyl hlorides arboxylic Acids, Esters ...
more infohttp://healthdocbox.com/Nutrition/68767975-1-sydney-australia-june-958.html
Frederick Klenner on Heart Disease Prevention and Treatment  Frederick Klenner on Heart Disease Prevention and Treatment
... acid is protected in vivo from rapid transformation to the antiscorbutically impotent diketogulonic acid from which oxalic acid ... acid goes to dehydroascorbic acid, then to ketogulonic acid and later to oxalic acid as the calcium salt; ... like virus nucleic acid, enzymatic action by ascorbic acid contributes to the breakdown of virus nucleic acid to adenosine ... Ascorbic acid, by mouth, is given to tolerance. Loose stools is accepted as this index. Using large doses of ascorbic acid I.V ...
more infohttp://www.angelfire.com/zine2/healthplan/page5.html
Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. - Semantic Scholar  Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. - Semantic Scholar
The ascorbic acid in plasma can be determined in 15 min, with as little as 50 microL of sample. Analytical recoveries are near ... Finally, because ascorbic acid prepared by the described procedures is stable at room temperature for at least 18 h, these ... indicate that ascorbic acid remains stable in stored plasma for as long as 57 weeks. CVs for round-robin analysis of 11 normal ... accurate analysis for ascorbic acid in human plasma. No sample extraction or phase separation is required. We also describe a ...
more infohttps://www.semanticscholar.org/paper/Stabilization-of-ascorbic-acid-in-human-plasma%2C-and-Margolis-Davis/dc6a5c05f915d322e6c96dd5b33a2dba83683b6a
Toxicity Effects  Toxicity Effects
BRAIN ASCORBIC ACID (VITAMIN C) LEVELS. ACCOMPANIED BY DEHYDROASCORBIC ACID & DIKETOGULONIC ACID ACCUMULATION IN LIVER & INCR ... IN RAT 32% OF THIOPHENE EXCRETED UNCHANGED IN EXPIRED AIR & 40% EXCRETED IN URINE AS MERCAPTURIC ACIDS.[BRAY HG ET AL; ... THIOPHEN IS METABOLIZED IN VIVO TO PREMERCAPTURIC ACID AND 2-THIENYL-MERCAPTURIC ACID.[The Chemical Society. Foreign Compound ... INHALATION OF 3 OR 20 MG/CU M OF THIOPHENE BY RATS OVER 80 DAY PERIOD DECR ADRENAL, KIDNEY, LIVER, & ...
more infohttps://tools.niehs.nih.gov/cebs3/ntpviews/index.cfm?action=testarticle.toxicity&cas_number=110-02-1
DoctorYourself.com - Klenner Vitamin C Paper  DoctorYourself.com - Klenner Vitamin C Paper
... acid is protected in vivo from rapid transformation to the antiscorbutically impotent diketogulonic acid from which oxalic acid ... like virus nucleic acid, enzymatic action by ascorbic acid contributes to the breakdown of virus nucleic acid to adenosine ... Five grams ascorbic acid was given in fruit juice every 6 hours by mouth and 6 grams ascorbic acid along with a B complex ... Ascorbic acid, by mouth, is given to tolerance. Loose stools is accepted as this index. Using large doses of ascorbic acid I.V ...
more infohttp://www.doctoryourself.com/klennerpaper.html
  • One ascorbate metabolite is 2,3-diketogulonate (DKG), preparations of which can non-enzymically generate H2O2 and delay peroxidase action on aromatic substrates. (usda.gov)
  • To understand the chemical behavior of ascorbic acid in human pathology, one must go beyond its present academic status either as a factor essential for life or as a substance necessary to prevent scurvy. (angelfire.com)
  • Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. (semanticscholar.org)
  • article{Margolis1988StabilizationOA, title={Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. (semanticscholar.org)
  • We describe two independent HPLC procedures for the rapid, accurate analysis for ascorbic acid in human plasma. (semanticscholar.org)
  • In organic chemistry , Acyclic Acids (Ethanoic Acids) , as organic compounds are 2 carbon straight-chain saturated carboxylic acids , that have an open-chain molecular structures as opposed to ring-shaped structures. (wellnessadvocate.com)
  • 3 P- HE vitamiils are organic substallces which, T although i~ldispensable in nutrition, are required in much smaller quantities than the major food co~lstitueiltsuch as carbohydrates, fats, and proteias. (healthdocbox.com)
  • Ascorbic acid is a naturally occurring organic compound with antioxidant properties. (wikipedia.org)
  • The phenolic contents of plant foods are commonly quantified by the Folin-Ciocalteu assay based on gallic acid equivalents (GAEs). (usda.gov)
  • However, this may lead to inaccuracies because gallic acid is not always representative of the structural heterogeneity of plant phenolics. (usda.gov)
  • 2 Source: the National Library of Medicine's Hazardous Substance Database , 02/28/2017. (nih.gov)
  • The net loss of body protein particularly skeletal muscle protein is likely to be a major factor responsible for PEM [ 1 , 2 ]. (hindawi.com)
  • 1997). Based on radioisotope measurements of ascorbic acid kinetics, the lungs appear to be a smaller but rapidly mobilized vitamin C pool, while the liver and muscle are larger, more slowly mobilized reserves (Toutain et al. (dsm.com)
  • Vitamin C occurs in two forms, L-ascorbic acid (reduced form) and dehydro-L-ascorbic acid (oxidized form). (dsm.com)
  • 1984). High levels of dietary iron, zinc, copper and pectin reduce the utilization of ascorbic acid, either by direct oxidation of vitamin C or by reducing its absorption (Sauberlich, 1990). (dsm.com)
  • Endogenous production of vitamin C is dependent on the presence or absence of the liver microsomal enzyme L-gluconolactone oxidase, which imparts the ability to synthesize ascorbic acid from monosaccharides (Lehninger, 1982). (dsm.com)
  • A second important feature of vitamin C metabolism is the interconversion of L-ascorbic acid and dehydro-L-ascorbic acid. (dsm.com)
  • When vitamin C intake far exceeds requirements, ascorbic acid is excreted in urine unchanged (Sauberlich, 1990). (dsm.com)
  • reported that vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting glyceraldehyde 3-phosphate dehydrogenase (GAPDH) through an ROS-dependent mechanism. (aimsci.com)
  • Vitamin B, (pyridoxin) is 2-methyl-3-hydroxy-4, 5-di (hydroxymethy1)- pyridine. (healthdocbox.com)
  • Lymphocyte and plasma vitamin C levels in type 2 diabetic patients with and without diabetes complications. (semanticscholar.org)
  • Vitamin C in plasma: a comparative study of the vitamin stabilized with trichloroacetic acid or metaphosphoric acid and the effects of storage at -70 degrees, -20 degrees, 4 degrees, and 25 degrees on the stabilized vitamin. (semanticscholar.org)
  • AOAC(1990a) Vitamin C (ascorbic acid) in vitamin preparations and juices. (springer.com)
  • AOAC (1990i) Vitamin C (ascorbic acid) in vitamin preparations. (springer.com)
  • Ascorbic acid is one form ("vitamer") of vitamin C. It was originally called L-hexuronic acid, but, when it was found to have vitamin C activity in animals ("vitamin C" being defined as a vitamin activity, not then a specific substance), the suggestion was made to rename it. (wikipedia.org)
  • The new name, ascorbic acid, is derived from a- (meaning "no") and scorbutus (scurvy), the disease caused by a deficiency of vitamin C. Because it is derived from glucose, many animals are able to produce it, but humans require it as part of their nutrition. (wikipedia.org)
  • Other vertebrates which lack the ability to produce ascorbic acid include some primates, guinea pigs, teleost fishes, bats, and some birds, all of which require it as a dietary micronutrient (that is, in vitamin form). (wikipedia.org)
  • In late 1931, King's lab obtained adrenal hexuronic acid indirectly from Szent-Györgyi and, using their animal model, proved that it is vitamin C, by early 1932. (wikipedia.org)
  • High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. (wha-www.org)
  • 146 patients were allocated to receive 2 5 mg vitamin D(3) or placebo at baseline and 14, 28, and 42 days after starting standard tuberculosis treatment. (wha-www.org)
  • Patients were genotyped for TaqI and FokI polymorphisms of the vitamin D receptor, and interaction analyses were done to assess the influence of the vitamin D receptor genotype on response to vitamin D(3). (wha-www.org)
  • Mean serum 25-hydroxyvitamin D concentration at 56 days was 101 4 nmol/L in the intervention group and 22 8 nmol/L in the placebo group.Interpretation: Administration of four doses of 2 5 mg vitamin D(3) increased serum 25-hydroxyvitamin D concentrations in patients receiving intensive-phase treatment for pulmonary tuberculosis. (wha-www.org)
  • In calves the major reservoirs of ascorbic acid are in the lungs, liver and muscle tissue (Toutain et al. (dsm.com)
  • 1965). With the exception of carbethoxylated ascorbic acid all the carbethoxylated derivatives of the beverage components are hydrolyzed by enzymes of the intestine, pancreas and liver to carbon dioxide and the basic substances. (inchem.org)
  • However, a repeat of model studies using gas chromatography and levels of 340-680 ppm NH 4+ /NH 3 and 800-1600 ppm DEPC from pH 4 to 10 showed urethane to be present, with a 5-12% (22-53 ppm) conversion to urethane at pH 4 (Gejvall & L froth, 1971). (inchem.org)
  • Specifically, 1.3 ppm of urethane was reported in beer with an ammonium content of 2 ppm, when treated with 500 ppm of the labelled DEPC (L froth & Gejvall, 1971). (inchem.org)
  • Volume 2: A Review of the Literature Published Between 1970 and 1971. (nih.gov)
  • 2. The composite material according to claim 1, wherein the reducing agent includes, carbon, and a concentration of the reducing agent is defined such that a concentration of the carbon is equal to or greater than 1 mass % of a total mass of the composite material. (patentsencyclopedia.com)
  • In the absence of oxygen ascorbic acid undergoes a slow anaerobic decomposition to carbon dioxide and residual products which have not been ft11ly identified. (healthdocbox.com)
  • The predominant reaction, however, remains the normal hydrolysis to CO 2 and ethanol. (inchem.org)
  • Ascorbic acid is also stabilized by the antioxidant enzymes superoxide dismutase and catalase (Miyake et al. (dsm.com)
  • In its metabolism, ascorbic acid is converted to dehydroascorbate by enzymatic or nonenzymatic means and can be enzymatically reduced back to ascorbic acid in cells in a glutathione-dependent reaction (Johnson et al. (dsm.com)
  • In biological systems, L-ascorbic acid can be reversibly oxidized to dehydro-L-ascorbic acid. (dsm.com)
  • Ascorbic acid analysis in biological fluids. (semanticscholar.org)
  • In 1937, the Nobel Prize for chemistry was awarded to Haworth for his work in determining the structure of ascorbic acid - shared with Paul Karrer, who received his award for work on vitamins - and the prize for Physiology or Medicine that year went to Albert Szent-Györgyi for his studies of the biological functions of L-ascorbic acid. (wikipedia.org)
  • Maximum concentration of these compounds have been isolated and identified in urine, whereas the average faecal excretion of VC or its metabolites was observed to be about 3% when administered orally in physiological amounts . (medcraveonline.com)
  • Szent-Györgyi isolated the chemical hexuronic acid first from plants and later from animal adrenal glands. (wikipedia.org)
  • Considerable quantities of ascorbic acid are secreted into the gastrointestinal tract and then re-absorbed as dehydroascorbate (Dabrowski, 1990). (dsm.com)
  • Plasma albumin [ 3 , 4 ], erythrocyte glutathione, and other endogenous antioxidant molecules such as bilirubin and uric acid [ 5 ] directly scavenge ROSs. (hindawi.com)
  • The primary enzymatic role of ascorbic acid in metabolism is that of a reducing agent for hydroxylation reactions (Sauberlich, 1990). (dsm.com)
  • Because of the unusually high amounts of ascorbic acid used in Dr. Klenner's treatment as reported in his paper, we asked him to verify amounts mentioned. (doctoryourself.com)
  • From 1967 on, Nobel prize winner Linus Pauling recommended high doses of ascorbic acid as a prevention against cold and cancer. (wikipedia.org)
  • We created elite inbred South African transgenic corn plants in which the levels of 3 vitamins were increased specifically in the endosperm through the simultaneous modification of 3 separate metabolic pathways. (pnas.org)
  • Concentration of VC in blood cells is much higher than in plasma, i.e. 3-4 times higher in red blood cells and 20-30 times higher in white blood cells. (medcraveonline.com)
  • We also describe a procedure for preparing a human plasma reference material for use in clinical laboratory analysis for ascorbic acid. (semanticscholar.org)
  • The ascorbic acid in plasma can be determined in 15 min, with as little as 50 microL of sample. (semanticscholar.org)
  • These 3 vitamins represent 3 entirely different metabolic pathways, and the only way to achieve such a radical change in the nutritional properties of an elite breeding variety of corn so rapidly is to take advantage of multigene engineering via direct DNA transfer ( 9 ). (pnas.org)
  • It can be split into p-aininobenzoylglutainic acid and a ilunlber of pteridine derivatives. (healthdocbox.com)
  • The reaction may also theoretically occur at acid pH where NH 4+ /NH 3 equilibria exists. (inchem.org)
  • It is vitally important that cognizance be taken of the demand by the body for ascorbic acid far beyond so-called scorbutic levels. (angelfire.com)