Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID.
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An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.
Drugs manufactured and sold with the intent to misrepresent its origin, authenticity, chemical composition, and or efficacy. Counterfeit drugs may contain inappropriate quantities of ingredients not listed on the label or package. In order to further deceive the consumer, the packaging, container, or labeling, may be inaccurate, incorrect, or fake.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Administrative units of government responsible for policy making and management of governmental activities.
A computerized biomedical bibliographic storage and retrieval system operated by the NATIONAL LIBRARY OF MEDICINE. MEDLARS stands for Medical Literature Analysis and Retrieval System, which was first introduced in 1964 and evolved into an online system in 1971 called MEDLINE (MEDLARS Online). As other online databases were developed, MEDLARS became the name of the entire NLM information system while MEDLINE became the name of the premier database. MEDLARS was used to produce the former printed Cumulated Index Medicus, and the printed monthly Index Medicus, until that publication ceased in December 2004.
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
A nitrofuran thiazine that has been used against TRYPANOSOMIASIS.
The agent of South American trypanosomiasis or CHAGAS DISEASE. Its vertebrate hosts are man and various domestic and wild animals. Insects of several species are vectors.
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.
Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).
Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)
Synthetic resins, containing an inert filler, that are widely used in dentistry.
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.
In about 250 species of electric fishes, modified muscle fibers forming disklike multinucleate plates arranged in stacks like batteries in series and embedded in a gelatinous matrix. A large torpedo ray may have half a million plates. Muscles in different parts of the body may be modified, i.e., the trunk and tail in the electric eel, the hyobranchial apparatus in the electric ray, and extrinsic eye muscles in the stargazers. Powerful electric organs emit pulses in brief bursts several times a second. They serve to stun prey and ward off predators. A large torpedo ray can produce of shock of more than 200 volts, capable of stunning a human. (Storer et al., General Zoology, 6th ed, p672)
A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Chromatographic techniques in which the mobile phase is a liquid.
Organic compounds that have a relatively high VAPOR PRESSURE at room temperature.
Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.
The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n.
Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
... ascorbic acid will undergo further oxidative decomposition to various products including diketogulonic acid, xylonic acid, ... Colour retention agent Erythorbic acid: a diastereomer of ascorbic acid. Mineral ascorbates: salts of ascorbic acid Acids in ... Ascorbic acid is an organic compound with formula C 6H 8O 6, originally called hexuronic acid. It is a white solid, but impure ... Ascorbic acid is a vinylogous acid and forms the ascorbate anion when deprotonated on one of the hydroxyls. This property is ...
Definition of 2,3-diketogulonic acid in the Definitions.net dictionary. Meaning of 2,3-diketogulonic acid. What does 2,3- ... diketogulonic acid mean? Information and translations of 2,3-diketogulonic acid in the most comprehensive dictionary ... Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID. ... Discuss these 2,3-diketogulonic acid definitions with the community:. Word of the Day. Would you like us to send you a FREE new ...
Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID. ... 2,3-Diketogulonic acid View Synonyms. View Structure. Description:. ...
ureidoglycolic acid (1R,2S,5S,6S)-2-(3-carboxypropanoyl)-5-[(1-carboxyvinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylic acid ... Annotations: Rat: (8363) Mouse: (8225) Human: (8584) Chinchilla: (0) Bonobo: (0) Dog: (2) Squirrel: (0) Pig: (13) ... 5-(2-hydroxyethyl)-4-methylthiazole 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl) ... 2,3,2,3-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + ...
Dehydroascorbic acid is irreversibly oxidized to the inactive diketogulonic acid. Since this change takes place readily, ... A 0.5% aqueous solution of ascorbic acid is strongly acid, with a pH of 3. Ascorbic acid is more stable in an acidic than an ... L-ascorbic acid is the most important of several compounds that have vitamin C activity. Ascorbic acid is commercially ... The L-isomer of ascorbic acid is biologically active, while the D-isomer is not. In biological systems, L-ascorbic acid can be ...
... and cloning of TpLDH and showing that amino acid insertions or deletions most notably corresponded to a 5-amino acid sequence ( ... Background: Ascorbic acid (Asc) is one of the most abundant antioxidants and it serves as a major contributor to protect plants ... To the control and sham groups, 2 mL of 0.9% NaCl was administred rectally, and in the argan oil group, 2 mL/day argan oil was ... In the control (Group 2) and argan oil (Group 3) groups, colonic resection and anastomosis were applied. ...
In certain fruits and developmental conditions, an alternative pathway from D-galacturonic acid might be also relevant. We here ... a number of animals including humans have lost the ability to synthesize ascorbic acid (ascorbate, vitamin C), an essential ... a number of animals including humans have lost the ability to synthesize ascorbic acid (ascorbate, vitamin C), an essential ... the main degradation products are oxalic acid, threonic acid and oxalyl threonic acid, but no tartaric acid has been detected ( ...
2006) Use of the affinity/HPLC method for quantitative estimation of folic acid in enriched cereal-grain products. J Nutr 136: ... 2000) Metabolic engineering of an alternative pathway for ascorbic acid biosynthesis in plants. Mol Breeding 6:73-78. ... 2006) Progress in manipulating ascorbic acid biosynthesis and accumulation in plants. Physiol Plant 126:343-355. ... A Single Amino Acid Substitution in an ORANGE Protein Promotes Carotenoid Overaccumulation in Arabidopsis ...
Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID. ... Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID.. ... 2,3-Diketogulonic Acid - Preferred Concept UI. M0023200. Scope note. ... We invite you to complete a survey that will take no more than 3 minutes.. Go to survey ...
Acyclic Acids are Carboxylic acids, a 2 carbon straight-chain saturated carboxylic acid, that has an open-chain molecular ... Acyclic Acids (Ethanoic Acids). "Acyclic Acids (Ethanoic Acids)" Acyclic Acid. In organic chemistry, Acyclic Acids (Ethanoic ... Uronic Acids *Glucuronates *Glucuronic Acid *Glucuronides *Hexuronic Acids *Iduronic Acid *Tricarboxylic Acids *Aconitic Acid * ... "Imino Acids (Secondary Amino Acids)" Secondary Amino Acids. In protein science, an Imino Acid (Secondary Amino Acid) is a ...
Background: Ascorbic acid (Asc) is one of the most abundant antioxidants and it serves as a major contributor to protect plants ... Valproic acid (VPA), an anti-epileptic drug, has been reported to cause male sub/infertility. Together with searching for ... SUMMARY: Retinoic acid, an active metabolite of vitamin A, plays essential signaling roles in mammalian embryogenesis. Prenatal ... Further, antioxidants, as well as alpha lipoic acid (ALA), may be a response to this pathological condition. The present study ...
"Sugar Acids" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Pseudaminic Acid on Exopolysaccharide of Acinetobacter baumannii Plays a Critical Role in Phage-Assisted Preparation of ... This graph shows the total number of publications written about "Sugar Acids" by people in Harvard Catalyst Profiles by year, ... Stereoselective Synthesis of 5-epi-a-Sialosides Related to the Pseudaminic Acid Glycosides. Reassessment of the ...
Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable ... "Neuraminic Acids" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human ... Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite. Nat Commun. 2016 Apr 04; 7:11187. ...
Dehydroascorbic Acid - Preferred Concept UI. M0005759. Scope note. The reversibly oxidized form of ascorbic acid. It is the ... deficiency: coordinate DEHYDROASCORBIC ACID/defic (IM) with ASCORBIC ACID DEFICIENCY (IM). Allowable Qualifiers:. AA analogs & ... The reversibly oxidized form of ascorbic acid. It is the lactone of 2,3-DIKETOGULONIC ACID and has antiscorbutic activity in ... We invite you to complete a survey that will take no more than 3 minutes.. Go to survey ...
Background: Ascorbic acid (Asc) is one of the most abundant antioxidants and it serves as a major contributor to protect plants ... Oxidoreductases/metabolism , Ascorbic Acid/administration & dosage , Tobacco/enzymology , Plants, Genetically Modified/ ... Ascorbic Acid/metabolism , Stress, Physiological , Tobacco/drug effects , Blotting, Western , Plants, Genetically Modified/drug ... We first found that the miR-17-5p and miR-20a of miR-17-92 directly target the 3UTR of FOG-2 and post-transcriptionally ...
Mitochondrial recycling of ascorbic acid from dehydroascorbic acid: dependence on the electron transport chain. Arch Biochem ... Characterization of ascorbic acid transport by adrenomedullary chromaffin cells. Evidence for Na+-dependent co-transport. J ... Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to ... Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation. Basic Clin ...
As most of you may know, vitamin C in the form of ascorbic acid oxidises easily to dehydroascorbic acid, which has an orange- ... I mix this in the AM with their ferulic acid/resveratrol serum and a drop of hyaluronic acid… ... Ascorbic acid is by far the most unstable form of vitamin C and oxidises very easily. While the other forms of vitamin C arent ... In the meantime, I have a jar of The Ordinary L-Ascorbic Acid Powder, and have been mixing it with Hada Labo Premium on a daily ...
To assay the effect of exogenously added FFA on DECR-dependent growth, oleic acid (OA) or linoleic Carsalam acid (LA) was added ... AH2ascorbic acid; AH?ascorbate anion; A?ascorbyl radical; ?OHhydroxyl radical; O?2superoxide anion. 3. Vitamin C: Anti-Cancer ... One-electron oxidation of ascorbic acid prospects LDE225 distributor to the formation of a stable and non-reactive ascorbic ... The pro-oxidative activity of ascorbic acid (Number 2) is definitely associated with the connection with transition metallic ...
VC: Vitamin c; L-AA: L-ascorbic acid; DHA: L-dehydroascorbic acid; GLO: l-Gulonolactone Oxidase Gene; LDL: Low Density ... Kyrtopoulos SA (1987) Ascorbic acid and the formation of N-nitroso compounds: possible role of ascorbic acid in cancer ... A study in USA stated that after supplementation with VC there was a decrease of 45% in level of uric acid with intake of 1500 ... Ohno S, Ohno Y, Suzuki N, Soma G, Inoue, M (2009) High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with ...
dehydroascorbic acid, etc ; ascorbic acid; chemical reactions; chemical bonding; glucobrassicin; cresols; coumaric acids; ... organic acids, ascorbic acid (AA), dehydroascorbic acid, and 2,3-diketogulonic acid were used to estimate the extent of NEB ... You searched for: Subject dehydroascorbic acid Remove constraint Subject: dehydroascorbic acid Text Availability Full Text ... dehydroascorbic acid, etc ; Nicotiana tabacum; cell suspension culture; cell cycle; ascorbic acid; oxidation; redox potential; ...
... organic acids, ascorbic acid (AA), dehydroascorbic acid, and 2,3-diketogulonic acid were used to estimate the extent of NEB ... Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino acids with protein anabolic properties ... maple syrup urine disease, etc ; amino acid composition; amino acid metabolism; case studies; cesarean section; compliance; ... rice syrup, etc ; Lactobacillus plantarum; beverages; cell viability; fermentation; lactic acid; lactic acid bacteria; ...
The ions represent dehydroascorbate (345), diketogu-lonic acid (415) and the proposed dicarboxylic acid species (505) Exposure ... diketogulonic acids and the C6 -dicarboxylic acid species. As shown in FIG. 4A, the relative amount of DHA (345 to 575 ratio) ... the diketogulonic acid and ketotrihydroxyadipic acid isomers illustrated herein, is a sensitive indicator of redox potential ... These are consistent with diketogulonic acid (triangles) and dicarboxylic acid (diamond).. DETAILED DESCRIPTION OF THE ...
... and reductic acid, which are decomposition products of L-ascorbic acid or D-araboascorbic acid. 16. A manufacturing method of ... 0059] The reason is in a feature of decomposition products of L-ascorbic acid. L-ascorbic acid is decomposed in order of ... For example, the reducing agent may include at least one of L-ascorbic acid, D-araboascorbic acid, the acetaldehyde 2,4-dinitro ... 0060] L-ascorbic acid, which is starting material, and reductic acid, which is a decomposition product, have keto-enediol ...
... ascorbic acid, dehydroascorbic acid, diketogulonic acid and furfural (Anon., 1965). In the reaction products resulting from ... The following substances were investigated in this respect; tricarbethoxy gallic acid, dicarbethoxy chlorogenic acid, mono- and ... hydroxy acids, ascorbic acid and ethanol. The predominant reaction, however, remains the normal hydrolysis to CO2 and ethanol. ... The reaction may also theoretically occur at acid pH where NH4+/NH3 equilibria exists. Model experiments using high levels of ...
12-S-Hydroxyeicosatetraenoic Acid use 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid ... acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester ... 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase use Testosterone 5-alpha-Reductase ... 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer ...
... sugar acid derivatives of organic compounds containing a saccharide unit that bears both an amine group and a carboxylic acid ... Sugar Amino Acids and derivatives are sugar acids and ... Sugar Amino Acids and derivatives "Sugar Amino Acids and ... In organic chemistry, Sugar Amino Acids and derivatives are sugar acids and sugar acid derivatives of organic compounds in the ... Sugar Amino Acids and derivatives ⌊Alchemy Center. ⌊Atoms. ⌊Polyatomic entities. ⌊Heteroatomic Molecular Entities. ⌊Organic ...
... ascorbic acid will undergo further oxidative decomposition to various products including diketogulonic acid, xylonic acid, ... Colour retention agent Erythorbic acid: a diastereomer of ascorbic acid. Mineral ascorbates: salts of ascorbic acid Acids in ... Ascorbic acid is an organic compound with formula C 6H 8O 6, originally called hexuronic acid. It is a white solid, but impure ... Ascorbic acid is a vinylogous acid and forms the ascorbate anion when deprotonated on one of the hydroxyls. This property is ...
  • Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID. (definitions.net)
  • Dehydroascorbic acid is irreversibly oxidized to the inactive diketogulonic acid. (dsm.com)
  • Reversible oxidation-reduction of ascorbic acid with dehydroascorbic acid is the most important chemical property of vitamin C and the basis for its known physiological activities and stabilities (Jaffe, 1984). (dsm.com)
  • 1999). Dehydroascorbic acid is the preferred form of vitamin C for uptake by erythrocytes, lymphocytes and neutrophils (Sauberlich, 1990). (dsm.com)
  • 1998). The selenium enzyme glutathione peroxidase is involved in the regeneration of ascorbic acid from dehydroascorbic acid in bovine erythrocytes (Washburn and Wells, 1999). (dsm.com)
  • As most of you may know, vitamin C in the form of ascorbic acid oxidises easily to dehydroascorbic acid, which has an orange-brown colour. (labmuffin.com)
  • However, dehydroascorbic acid also decomposes, and it does it irreversibly. (labmuffin.com)
  • L-ascorbic acid (L-AA) is the main biologically active form of VC, reversible oxidation of L-AA results in formation of L-dehydroascorbic acid (DHA) which also has biological activity [5]. (medcraveonline.com)
  • 15. The manufacturing method according to claim 13, wherein the metal includes copper, and the reducing agent in the eutectoid is at least one of dehydroascorbic acid, 2,3-diketogulonic acid, L-xylosone, 2-ketoglutaric aldehyde, and reductic acid, which are decomposition products of L-ascorbic acid or D-araboascorbic acid. (patentsencyclopedia.com)
  • Mono- and dicarbethoxy ascorbic acid are not enzymatically hydrolyzed, but spontaneous decomposition occurs (with a half-life time of five to 10 days) to carbon dioxide, ascorbic acid, dehydroascorbic acid, diketogulonic acid and furfural (Anon. (inchem.org)
  • The oxidized form (dehydroascorbic acid) is still biologically active, but is rapidly hydrolysed with opening of the lactone ring to give an inactive open chain conlpou~ld (diketogulonic acid). (healthdocbox.com)
  • Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization. (semanticscholar.org)
  • An improved method for determination of L-ascorbic acid and L-dehydroascorbic acid in blood plasma. (semanticscholar.org)
  • Determination of ascorbic acid and dehydroascorbic acid in plasma and cerebrospinal fluid by liquid chromatography with electrochemical detection. (semanticscholar.org)
  • It is oxidized with loss of one electron to form a radical cation and then with loss of a second electron to form dehydroascorbic acid. (wikipedia.org)
  • In carbohydrate science , Sugar Acids , as an acyclic acid , are acidic sugars. (wellnessadvocate.com)
  • Sugar Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Sugar Acids" by people in Harvard Catalyst Profiles by year, and whether "Sugar Acids" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Sugar Acids" by people in Profiles. (harvard.edu)
  • In organic chemistry, Sugar Amino Acids and derivatives are sugar acids and sugar acid derivatives of organic compounds in the carbohydrates and carbohydrate conjugates subclass in the organooxygen compounds class within the organic oxygen compounds superclass , containing a saccharide unit that bears both an amine group and a carboxylic acid group. (wellnessadvantage.com)
  • Reassessment of the Stereoselectivity of the 5-Azido-5-deacetamidosialyl Thioglycosides and Use of Triflate as Nucleophile in the Zbiral Deamination of Sialic Acids. (harvard.edu)
  • The role of sialic acids in the immune recognition of xenografts. (harvard.edu)
  • 3 P- HE vitamiils are organic substallces which, T although i~ldispensable in nutrition, are required in much smaller quantities than the major food co~lstitueiltsuch as carbohydrates, fats, and proteias. (healthdocbox.com)
  • Investigations using labelled diethyl pyrocarbonate revealed that it reacts principally with amino acids, polyphenols, hydroxy acids, ascorbic acid and ethanol. (inchem.org)
  • Endogenous production of vitamin C is dependent on the presence or absence of the liver microsomal enzyme L-gluconolactone oxidase, which imparts the ability to synthesize ascorbic acid from monosaccharides (Lehninger, 1982). (dsm.com)
  • Throughout evolution, a number of animals including humans have lost the ability to synthesize ascorbic acid (ascorbate, vitamin C), an essential molecule in the physiology of animals and plants. (frontiersin.org)
  • The main feature that stands out from other species is its enormous capacity to synthesize ascorbic acid. (brazilianjournals.com)
  • Bui-Nguyen, M., J., "Application of High-performance liquid chromatograpy to the separation of ascorbic acid from isoascorbic acid," J. Chrom. (freepatentsonline.com)
  • One ascorbate metabolite is 2,3-diketogulonate (DKG), preparations of which can non-enzymically generate H2O2 and delay peroxidase action on aromatic substrates. (usda.gov)
  • It directly regenerates Asc from its oxidized state and thus prevents Asc from being irreversibly hydrolyzed to 2, 3-diketogulonic acid. (bvsalud.org)
  • L-Ascorbic Acid (L-threo-hex-2-enono-1,4-lactone, ascorbate), also called vitamin C, is an essential antioxidant molecule in plant and animal metabolism and also functioning as a cofactor in many enzymes. (frontiersin.org)
  • Vitamin C, also known as ascorbic acid or ascorbate, is a water-soluble molecule synthesized endogenously in animals except humans, monkeys, guinea pigs, and several other animal species [1]. (aimsci.com)
  • Production of 2-Keto-L-Gulonate, an Intermediate in L-Ascorbate Synthesis, by a Genetically Modified Erwinia herbicola," Science, 230(11): 144-149, 1985. (freepatentsonline.com)
  • Ascorbic acid is a vinylogous acid and forms the ascorbate anion when deprotonated on one of the hydroxyls. (wikipedia.org)
  • This property is characteristic of reductones: enediols with a carbonyl group adjacent to the enediol group, namely with the group -C(OH)=C(OH)-C(=O)-. The ascorbate anion is stabilized by electron delocalization that results from resonance between two forms: For this reason, ascorbic acid is much more acidic than would be expected if the compound contained only isolated hydroxyl groups. (wikipedia.org)
  • Nucleophilic attack of ascorbic acid on a proton results in a 1,3-diketone: The ascorbate ion is the predominant species at typical biological pH values. (wikipedia.org)
  • In organic chemistry , Acyclic Acids (Ethanoic Acids) , as organic compounds are 2 carbon straight-chain saturated carboxylic acids , that have an open-chain molecular structures as opposed to ring-shaped structures. (wellnessadvocate.com)
  • Nicotinic acid (niacin) is pyridine-3-carboxylic acid. (healthdocbox.com)
  • EDTA is a polyamino carboxylic acid, a colorless water-soluble metallo-chelator and is known to have intrinsic antimicrobial activity. (ijpsr.com)
  • Because of the unusually high amounts of ascorbic acid used in Dr. Klenner's treatment as reported in his paper, we asked him to verify amounts mentioned. (doctoryourself.com)
  • Although in nature, ascorbic acid is the predominant form, both forms are biologically active. (dsm.com)
  • The L-isomer of ascorbic acid is biologically active, while the D-isomer is not. (dsm.com)
  • Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. (semanticscholar.org)
  • article{Margolis1988StabilizationOA, title={Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. (semanticscholar.org)
  • We describe two independent HPLC procedures for the rapid, accurate analysis for ascorbic acid in human plasma. (semanticscholar.org)
  • To understand the chemical behavior of ascorbic acid in human pathology, one must go beyond its present academic status either as a factor essential for life or as a substance necessary to prevent scurvy. (angelfire.com)
  • 2 Source: the National Library of Medicine's Hazardous Substance Database , 02/28/2017. (nih.gov)
  • 6 → ROH + C6H6O6 On exposure to oxygen, ascorbic acid will undergo further oxidative decomposition to various products including diketogulonic acid, xylonic acid, threonic acid and oxalic acid. (wikipedia.org)
  • Determination of ascorbic acid in algae by high-performance liquid chromatography on strong cation-exchange resin with electrochemical detection. (semanticscholar.org)
  • Augustin, J., Beck, C. and Marousek, G.I. (1981) Quantitative determination of ascorbic acid in potatoes and potato products by high performance liquid chromatography. (springer.com)
  • In protein science , an Imino Acid (Secondary Amino Acid) is a molecule, related to amino acids (differing in the bonding to the nitrogen), that contains both an imino (>C=NH) and a carboxyl (-C(=O)-OH) functional group, which occurs as either an acyclic acid or a cyclic imino acid . (wellnessadvocate.com)
  • They are divided into two groups : (1) water-soluble and (2) fat-soluble. (healthdocbox.com)
  • Water-soluble Vitamins The structure of vitailli~l C (ascorbic acid) is sllonlll in the figure on p. 23. (healthdocbox.com)
  • These compounds are water-soluble and, thus, cannot protect fats from oxidation: For this purpose, the fat-soluble esters of ascorbic acid with long-chain fatty acids (ascorbyl palmitate or ascorbyl stearate) can be used as food antioxidants. (wikipedia.org)
  • The primary enzymatic role of ascorbic acid in metabolism is that of a reducing agent for hydroxylation reactions (Sauberlich, 1990). (dsm.com)
  • In the absence of oxygen ascorbic acid undergoes a slow anaerobic decomposition to carbon dioxide and residual products which have not been ft11ly identified. (healthdocbox.com)
  • Ascorbic acid is metabolized to 2,3-diketogulonic acid and oxalate and excreted in the urine (Sauberlich, 1990). (dsm.com)
  • The metabolites of vitamin C in humans are oxalate, dehydro-ascorbic acid, 2,3-diketogulonic acid, ascorbic acid 2-sulphate and saccharo-ascorbic acid. (medcraveonline.com)
  • AA is a small antioxidant molecule, vitamin C (L-ascorbic acid), fulfils essential metabolic functions in the life of animals and plants. (annualfarewelltour.com)
  • Of the five strains of lactic acid bacteria tested, L. plantarum was preferentially selected in terms of a viable cells (7.3 × 10⁸ colony forming unit (CFU/mL) and higher dry cell weight (13 mg/mL). (usda.gov)
  • Ascorbic acid decomposes into desoxyascorbic, oxaloacetic and diketogulonic acids, bendazole into two conjugates, thymogen to glutamic acid and tryptophan, which are not excreted by the body, but participate in the synthesis of the protein. (medhelpsis.com)
  • Vitamin C occurs in two forms, L-ascorbic acid (reduced form) and dehydro-L-ascorbic acid (oxidized form). (dsm.com)
  • 1984). High levels of dietary iron, zinc, copper and pectin reduce the utilization of ascorbic acid, either by direct oxidation of vitamin C or by reducing its absorption (Sauberlich, 1990). (dsm.com)
  • A second important feature of vitamin C metabolism is the interconversion of L-ascorbic acid and dehydro-L-ascorbic acid. (dsm.com)
  • 1997). Based on radioisotope measurements of ascorbic acid kinetics, the lungs appear to be a smaller but rapidly mobilized vitamin C pool, while the liver and muscle are larger, more slowly mobilized reserves (Toutain et al. (dsm.com)
  • When vitamin C intake far exceeds requirements, ascorbic acid is excreted in urine unchanged (Sauberlich, 1990). (dsm.com)
  • reported that vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting glyceraldehyde 3-phosphate dehydrogenase (GAPDH) through an ROS-dependent mechanism. (aimsci.com)
  • But recently, I came across a diagram in a peer-reviewed paper on a completely different topic that accidentally told me exactly why vitamin C does this: ascorbic acid eventually oxidises to erythrulose ! (labmuffin.com)
  • So that's why vitamin C serums can stain - the ascorbic acid essentially turn into fake tan on your skin! (labmuffin.com)
  • You can use an antioxidant-rich formulation like vitamin C + vitamin E + ferulic acid (e.g. (labmuffin.com)
  • Ascorbic acid is by far the most unstable form of vitamin C and oxidises very easily. (labmuffin.com)
  • Vitamin B, (pyridoxin) is 2-methyl-3-hydroxy-4, 5-di (hydroxymethy1)- pyridine. (healthdocbox.com)
  • 2] Several clinical studies have shown that high H. pylori infection rate is related to low ascorbic acid (AA)/Vitamin C (Vit C) level in serum as well as in gastric juice. (nutriforce.cn)
  • Lymphocyte and plasma vitamin C levels in type 2 diabetic patients with and without diabetes complications. (semanticscholar.org)
  • Vitamin C in plasma: a comparative study of the vitamin stabilized with trichloroacetic acid or metaphosphoric acid and the effects of storage at -70 degrees, -20 degrees, 4 degrees, and 25 degrees on the stabilized vitamin. (semanticscholar.org)
  • In plasma, uric acid and ascorbic acid together contribute around 80% of the total antioxidant activity, which is around 1000 ОјM, the rest being largely vitamin E, bilirubin, and protein. (annualfarewelltour.com)
  • AOAC(1990a) Vitamin C (ascorbic acid) in vitamin preparations and juices. (springer.com)
  • AOAC (1990i) Vitamin C (ascorbic acid) in vitamin preparations. (springer.com)
  • High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. (wha-www.org)
  • 146 patients were allocated to receive 2 5 mg vitamin D(3) or placebo at baseline and 14, 28, and 42 days after starting standard tuberculosis treatment. (wha-www.org)
  • Patients were genotyped for TaqI and FokI polymorphisms of the vitamin D receptor, and interaction analyses were done to assess the influence of the vitamin D receptor genotype on response to vitamin D(3). (wha-www.org)
  • Mean serum 25-hydroxyvitamin D concentration at 56 days was 101 4 nmol/L in the intervention group and 22 8 nmol/L in the placebo group.Interpretation: Administration of four doses of 2 5 mg vitamin D(3) increased serum 25-hydroxyvitamin D concentrations in patients receiving intensive-phase treatment for pulmonary tuberculosis. (wha-www.org)
  • Vitamin A occurs in two common forms, vitamin A 1 , or ret inol , the form most common in mammalian tissues and marine fishes, and vitamin, A 2 , common in freshwater fishes. (tdmuv.com)
  • The vitamin A requirement of man - 1,5-2 milligram per day. (tdmuv.com)
  • Most important are vitamin D 2 , or ergocalciferol , and vitamin D 3 , or cholecalciferol , the form normally found in mammals. (tdmuv.com)
  • 1965). With the exception of carbethoxylated ascorbic acid all the carbethoxylated derivatives of the beverage components are hydrolyzed by enzymes of the intestine, pancreas and liver to carbon dioxide and the basic substances. (inchem.org)
  • It can be split into p-aininobenzoylglutainic acid and a ilunlber of pteridine derivatives. (healthdocbox.com)
  • In addition, anthocyanins, ellagic acid derivatives, and hydrolyzable tannins were detected and quantified in the pomegranate juices. (annualfarewelltour.com)
  • A receptor-binding protein of Campylobacter jejuni bacteriophage NCTC 12673 recognizes flagellin glycosylated with acetamidino-modified pseudaminic acid. (harvard.edu)
  • These results indicate that the miR-17-92 cluster regulates the expression of FOG-2 protein and suggest that the miR-17-92 cluster might play an important role in heart development. (bvsalud.org)
  • The net loss of body protein particularly skeletal muscle protein is likely to be a major factor responsible for PEM [ 1 , 2 ]. (hindawi.com)
  • Nucleic acid evolution and minimization, 2002, Nat. (freepatentsonline.com)
  • Reactive oxygen species are damaging to animals and plants at the molecular level due to their possible interaction with nucleic acids, proteins, and lipids. (wikipedia.org)
  • 18 19 20 31 In tears, uric acid and ascorbic acid account for around half the total antioxidant activity. (annualfarewelltour.com)
  • Plasma albumin [ 3 , 4 ], erythrocyte glutathione, and other endogenous antioxidant molecules such as bilirubin and uric acid [ 5 ] directly scavenge ROSs. (hindawi.com)
  • The phenolic contents of plant foods are commonly quantified by the Folin-Ciocalteu assay based on gallic acid equivalents (GAEs). (usda.gov)
  • However, this may lead to inaccuracies because gallic acid is not always representative of the structural heterogeneity of plant phenolics. (usda.gov)
  • Ascorbic acid is an organic compound with formula C 6H 8O 6, originally called hexuronic acid. (wikipedia.org)
  • Between 1928 and 1932, Albert Szent-Györgyi isolated a candidate for this substance, which he called it "hexuronic acid", first from plants and later from animal adrenal glands. (wikipedia.org)
  • In 1933, sugar chemist Walter Norman Haworth, working with samples of "hexuronic acid" that Szent-Györgyi had isolated from paprika and sent him in the previous year, deduced the correct structure and optical-isomeric nature of the compound, and in 1934 reported its first synthesis. (wikipedia.org)
  • Acetoacetic Acid concentrations of up to 200 mg/dL did not interfere with glucose assay test results (no false negative results). (alcalalabs.com)
  • Glucose oxidase catalyzes the formation of gluconic acid and hydrogen peroxide via the oxidation of glucose. (alcalalabs.com)
  • It creates volatile compounds when mixed with glucose and amino acids in 90 °C. It is a cofactor in tyrosine oxidation. (wikipedia.org)
  • The Determination of Ascorbic and Erythorbic Acids in Meat Products", J. Assoc. Pub. (freepatentsonline.com)
  • The determination of ascorbic acid levels was done by titration of Tillman, on two clone's fruits. (brazilianjournals.com)
  • Maximum concentration of these compounds have been isolated and identified in urine, whereas the average faecal excretion of VC or its metabolites was observed to be about 3% when administered orally in physiological amounts [9]. (medcraveonline.com)
  • 20(2):209-222, mayo - agosto de 2015 - 211, the content of total phenolic compounds, ascorbic acid, betacyanin, betaxanthin and the stability of betacyanin pigments in presence of Cu (II)-dependent hydroxyl radicals (OH•), in 18 cultivars of purple, red, yellow and white cactus pear from six Mexican states. (annualfarewelltour.com)
  • Ascorbic acid and its sodium, potassium, and calcium salts are commonly used as antioxidant food additives. (wikipedia.org)
  • The main use of l-ascorbic acid and its salts is as food additives, mostly to combat oxidation. (wikipedia.org)
  • The predominant reaction, however, remains the normal hydrolysis to CO 2 and ethanol. (inchem.org)
  • We created elite inbred South African transgenic corn plants in which the levels of 3 vitamins were increased specifically in the endosperm through the simultaneous modification of 3 separate metabolic pathways. (pnas.org)
  • These 3 vitamins represent 3 entirely different metabolic pathways, and the only way to achieve such a radical change in the nutritional properties of an elite breeding variety of corn so rapidly is to take advantage of multigene engineering via direct DNA transfer ( 9 ). (pnas.org)
  • Ascorbic acid is also stabilized by the antioxidant enzymes superoxide dismutase and catalase (Miyake et al. (dsm.com)
  • Ascorbic acid is an antioxidant, neutralizes oxygen radicals, which are produced by inflammation, increases the body's resistance to respiratory infections. (medhelpsis.com)
  • Impact of ascorbic acid and О±-tocopherol on antioxidant activity of flax cultivars under salinity stress Acta biol. (annualfarewelltour.com)
  • The reduction and 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging ability of this compound were analyzed to assess its antioxidant potential. (annualfarewelltour.com)
  • Benzie IFF & Strain JJ (1999) Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. (annualfarewelltour.com)
  • antioxidant activity, phenolic, flavonoid and ascorbic acid contents of commonly consumed vegetables in Nigeria and identify which of these vegetables has the highest Investigation of Antioxidant and Hepatoprotective Activity of Standardized Curcuma xanthorrhiza Rhizome in Carbon Tetrachloride-Induced Hepatic Damaged Rats. (annualfarewelltour.com)
  • The objective of this study was to quantify the content of total phenolics, total betalains, ascorbic acid and antioxidant activity found in the juice, pulp and rind of the two commercial varieties of prickly pear. (annualfarewelltour.com)
  • Further, antioxidants, as well as alpha lipoic acid (ALA), may be a response to this pathological condition. (bvsalud.org)
  • Background: Ascorbic acid (Asc) is one of the most abundant antioxidants and it serves as a major contributor to protect plants against oxidative damage. (bvsalud.org)
  • This reaction is reversible, so you can get back the ascorbic acid if you have the right antioxidants in the formula. (labmuffin.com)
  • 0.005) decrease in enzymes activities (Superoxide dismutase, catalase and ascorbic acid) along with increased lipid peroxidation level as well as cytokine parameters (tumour necrosis factor-α, interlukin-6) and biochemical parameters in plasma of infected group as compared to control group. (ijpsr.com)
  • Ascorbic acid can also react with organic acids as an alcohol forming esters such as ascorbyl palmitate and ascorbyl stearate. (wikipedia.org)
  • In calves the major reservoirs of ascorbic acid are in the lungs, liver and muscle tissue (Toutain et al. (dsm.com)
  • However, a repeat of model studies using gas chromatography and levels of 340-680 ppm NH 4+ /NH 3 and 800-1600 ppm DEPC from pH 4 to 10 showed urethane to be present, with a 5-12% (22-53 ppm) conversion to urethane at pH 4 (Gejvall & L froth, 1971). (inchem.org)
  • Specifically, 1.3 ppm of urethane was reported in beer with an ammonium content of 2 ppm, when treated with 500 ppm of the labelled DEPC (L froth & Gejvall, 1971). (inchem.org)
  • Volume 2: A Review of the Literature Published Between 1970 and 1971. (nih.gov)
  • 2. The composite material according to claim 1, wherein the reducing agent includes, carbon, and a concentration of the reducing agent is defined such that a concentration of the carbon is equal to or greater than 1 mass % of a total mass of the composite material. (patentsencyclopedia.com)
  • High specific gravity, acidic pH values and gentisic acid may inhibit color formation. (alcalalabs.com)
  • 14] This experiment was carried out in buffered condition at pH 7.4, but in vivo H. pylori have to counter unbuffered acidic pH (pH 3) to colonize successfully into the stomach. (nutriforce.cn)
  • This study aimed to identify the main gene expression responsible to biosynthesis of ascorbic acid and two isoforms of AOX (1 and 2), on flowers and fruits at different development stages, on two clones the acerola called Cereja and Roxinha. (brazilianjournals.com)
  • Acerola, Ascorbic acid, Alternative Oxidase. (brazilianjournals.com)
  • In its metabolism, ascorbic acid is converted to dehydroascorbate by enzymatic or nonenzymatic means and can be enzymatically reduced back to ascorbic acid in cells in a glutathione-dependent reaction (Johnson et al. (dsm.com)