Amines: A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)Amine Oxidase (Copper-Containing): A group of enzymes including those oxidizing primary monoamines, diamines, and histamine. They are copper proteins, and, as their action depends on a carbonyl group, they are sensitive to inhibition by semicarbazide.Biogenic Amines: A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.Octopamine: An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.Receptors, Biogenic Amine: Cell surface proteins that bind biogenic amines with high affinity and regulate intracellular signals which influence the behavior of cells. Biogenic amine is a chemically imprecise term which, by convention, includes the catecholamines epinephrine, norepinephrine, and dopamine, the indoleamine serotonin, the imidazolamine histamine, and compounds closely related to each of these.Tyramine: An indirect sympathomimetic. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase so it prolongs the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals. Tyramine may be a neurotransmitter in some invertebrate nervous systems.SemicarbazidesOxidoreductases Acting on CH-NH Group Donors: Enzymes catalyzing the dehydrogenation of secondary amines, introducing a C=N double bond as the primary reaction. In some cases this is later hydrolyzed.Heterocyclic Compounds: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)MethylaminesMonoamine Oxidase: An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 22.214.171.124.Sympathomimetics: Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.EthylaminesDihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.Phenethylamines: A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed)Serotonin: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Amination: The creation of an amine. It can be produced by the addition of an amino group to an organic compound or reduction of a nitro group.Carcinogens: Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.ToluidinesButylaminesPhenylhydrazines: Diazo derivatives of aniline, used as a reagent for sugars, ketones, and aldehydes. (Dorland, 28th ed)Benzylamines: Toluenes in which one hydrogen of the methyl group is substituted by an amino group. Permitted are any substituents on the benzene ring or the amino group.Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Nitrosamines: A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.PolyaminesMonoamine Oxidase Inhibitors: A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414)Mutagens: Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.Vesicular Biogenic Amine Transport Proteins: Integral membrane proteins of the LIPID BILAYER of SECRETORY VESICLES that catalyze transport and storage of biogenic amine NEUROTRANSMITTERS such as ACETYLCHOLINE; SEROTONIN; MELATONIN; HISTAMINE; and CATECHOLAMINES. The transporters exchange vesicular protons for cytoplasmic neurotransmitters.Diamines: Organic chemicals which have two amino groups in an aliphatic chain.Aminobiphenyl Compounds: Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.Arylamine N-Acetyltransferase: An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without COENZYME A and has a wide specificity for aromatic amines, including SEROTONIN. However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also referred to as SEROTONIN ACETYLTRANSFERASE.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Kinetics: The rate dynamics in chemical or physical systems.Metaraminol: A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.Catalysis: The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.Benzylamine Oxidase: An aspect of monoamine oxidase, EC 126.96.36.199. Catalyzes the oxidation of benzylamine to form benzaldehyde, ammonia and hydrogen peroxide.Biotransformation: The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.IminesCadaverine: A foul-smelling diamine formed by bacterial decarboxylation of lysine.Tryptamines: Decarboxylated monoamine derivatives of TRYPTOPHAN.Structure-Activity Relationship: The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Biogenic Monoamines: Biogenic amines having only one amine moiety. Included in this group are all natural monoamines formed by the enzymatic decarboxylation of natural amino acids.Cooking: The art or practice of preparing food. It includes the preparation of special foods for diets in various diseases.Dopamine: One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.Putrescine: A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine.Carbolines: A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.Aniline CompoundsBenzidines: Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.Mutagenicity Tests: Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Imidazoles: Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).QuinolinesSynephrine: Sympathetic alpha-adrenergic agonist with actions like PHENYLEPHRINE. It is used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.PropylaminesImipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.Catecholamines: A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.Copper: A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.DimethylaminesSubstrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Deamination: The removal of an amino group (NH2) from a chemical compound.Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).PQQ Cofactor: A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.DNA Adducts: The products of chemical reactions that result in the addition of extraneous chemical groups to DNA.Aldehydes: Organic compounds containing a carbonyl group in the form -CHO.Epinephrine: The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.QuinoxalinesTranylcypromine: A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)Ethylenediamines
Certain medication (like amine-containing drugs) can increase the risk of craniosynostosis when taken during pregnancy, these ... Environmental factors refer for example to maternal smoking and the maternal exposure to amine-containing drugs. Several ... Wilkie AO (1997). "Craniosynostosis: genes and mechanisms". Human Molecular Genetics. 6 (10): 1647-56. doi:10.1093/hmg/6.10. ... Moloney DM, Wall SA, Ashworth GJ, Oldridge M, Glass IA, Francomano CA, Muenke M, Wilkie AO (April 1997). "Prevalence of ...
Železov(III) klorid - Wikipedija, prosta enciklopedija
A. Kamal, K. Ramana, H. Ankati, A. Ramana (2002). Mild and efficient reduction of azides to amines: synthesis of fused [2,1-b] ... Skupaj z natrijevim jodidom in acetonitrilom se uporablja za blago redukcijo organskih azidov v primarne amine. ... N.N. Greenwood, A. Earnshaw (1997). Chemistry of the Elements. 2. izdaja. Oxford: Butterworth-Heinemann. ...
Commercially sold indinavir is indinavir anhydrous, which is indinavir with an additional amine in the hydroxyethylene backbone ... September 1997). "A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus ... Capaldini L (August 1997). "Protease inhibitors' metabolic side effects: cholesterol, triglycerides, blood sugar, and "Crix ... September 1997). "Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection ...
... s dissolve in liquid ammonia or other donor solvents like aliphatic amines or hexamethylphosphoramide to give blue ... T. (1997). The Chemistry of Aqua Ions. Wiley. ISBN 978-0-471-97058-3. .. ... Lindsey, Jack L (1997). Applied illumination engineering. p. 112. ISBN 978-0-88173-212-2. .. ... Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 978-0-08-037941-8 ...
No significant rise in blood pressure occurs when moclobemide is combined with amines such as tyramine-containing foods or ... Markianos M, Alevizos V, Stefanis C (1991). "Plasma sex hormones and urinary biogenic amine metabolites during treatment of ... Single or repeated dosing with 100-300 mg of moclobemide leads to a reduction in deaminated metabolites of amines such as 3,4- ... The reversible binding to MAO-A by moclobemide allows amines such as tyramine to displace moclobemide from MAO-A allowing its ...
FITC reacts with the amine groups of many biologically relevant compounds including intracellular proteins to form a thiourea ... succinimidyl ester modified fluorescein, i.e. NHS-fluorescein, is another common amine-reactive derivative, yielding amide ... Sun, W. C.; Gee, K. R.; Klaubert, D. H.; Haugland, R. P. (1997). "Synthesis of Fluorinated Fluoresceins". The Journal of ...
Surface-enhanced Raman spectroscopy
உயிர்ச்சத்து - தமிழ் விக்கிப்பீடியா
The acetylation event converts the positively charged amine group on the side chain into a neutral amide linkage. This removes ... Boeree, C. George, (1997/2006), Personality Theories, Erik Erikson. *^ Erikson, Erik (1968). Identity: Youth and Crisis. ... Chuang LS, Ian HI, Koh TW, Ng HH, Xu G, Li BF (September 1997). "Human DNA-(cytosine-5) methyltransferase-PCNA complex as a ...
Solid-phase peptide synthesis on a rink amide resin using Fmoc-α-amine-protected amino acid ... due to the release of either a hydrogen ion from the amine end or a hydroxyl ion (OH−) from the carboxyl (COOH) end, or both, ... the "Gold Book") (1997). Online corrected version: (2006-) "amino-acid residue in a polypeptide". ... Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M ...
The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions. In ... with amines, e.g. the reaction of the amine sarcosine with cyanamide yields creatine ... Nitriles can be obtained from primary amines via oxidation. Common methods include the use of potassium persulfate, ... Chen, Fen-Er; Kuang, Yun-Yan; Hui-Fang, Dai; Lu, Liang (2003). "A Selective and Mild Oxidation of Primary Amines to Nitriles ...
The new quinoline heterocycle would then be formed by combining this amine with the aldehyde produced in the tryptamine side- ... Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, ... Ring opening in the indole heterocyclic ring could generate new amine and keto functions. ... Olmsted J, Williams GM (1997). Chemistry: The Molecular Science. Jones & Bartlett Learning. p. 137. ISBN 978-0-815-18450-8. . ...
... industrial dyestuffs and aromatic amines. Proceedings. Lyon, France, 6-13 October 1992". IARC Monogr Eval Carcinog Risks Hum. ... "Some aromatic amines, organic dyes, and related exposures". IARC Monographs on the Evaluation of Carcinogenic Risks to Humans ... Lamb, James (Feb 1997). "Reproductive toxicology. Lead acetate trihydrate". Environ Health Perspect. 105: 315-316. doi:10.2307/ ...
are allergic to sympathomimetic amine drugs.. *are taking a monoamine oxidase inhibitor (MAOI) or have taken one within the ... we confirmed agonistic activity at human TAAR1 of several other compounds, including the trace amines octopamine and tryptamine ... In 1997, after 24 cases of heart valve disease in fen-phen users, fenfluramine and dexfenfluramine were voluntarily taken off ... "Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence ...
Serotonin-norepinephrine reuptake inhibitor
This structural motif has potential for high affinity binding to biogenic amine transports. Drugs containing an ... This is because of a formation of secondary amine TCA metabolites. ... The mechanism of action of tricyclic secondary amine antidepressants is only partly understood. TCAs have dual inhibition ... 3-arylpropan-1-amines". Bioorganic & Medicinal Chemistry. 14 (24): 8455-66. doi:10.1016/j.bmc.2006.08.039. PMID 16973367.. ...
Alexander Shulgin, den frie encyklopædi
with Nichols, D. E. "Sulfur analogs of psychotomimetic amines". J. Pharm. Sci. 65: 1554-1556. 89 ... with Shulgin, Ann (1997). "A New Vocabulary". I Forte, Robert. Entheogens and the Future of Religion. Berkeley: Council on ... with Shulgin, Ann (1997). TIHKAL: The Continuation. Berkeley: Transform Press. ISBN 0-9630096-9-9.. . ...
Mass spectral interpretation
Amines. Amines follow nitrogen rule. Odd molecular ion mass-to-charge ratio suggests existence of odd numbers of ... Nonetheless, molecular ion peaks are weak in aliphatic amines due to the ease of fragmentation next to amines. Alpha-cleavage ... the "Gold Book") (1997). Online corrected version: (2006-) "electron ionization". *^ a b c d e f g h Pavia, Donald L. ... Aromatic amines have intense molecular ion peaks. For anilines, they prefer to lose a hydrogen atom before the expulsion of HCN ...
The basic chemical structure of the lolines comprises a saturated pyrrolizidine ring, a primary amine at the C-1 carbon, and an ... 1). Different substituents at the C-1 amine, such as methyl, formyl, and acetyl groups, yield loline species that have variable ... The lolines may be neurotoxic to the insects, and differences in the chemical groups at the C-1-amine result in different ... for oxygenation of one methyl group on the C-1 amine of N-methylloline, which gives the most abundant loline in many grass- ...
5-HT4受體 - 维基百科，自由的百科全书
trace-amine receptor activity. • identical protein binding. • neurotransmitter receptor activity. 細胞組分. • 細胞質. • integral ... December 1997, 78 (2): 133-4. PMID 9371406. doi:10.1159/000134646.. *^ Blondel O, Vandecasteele G, Gastineau M, Leclerc S, ... November 1997, 69 (5): 1810-9. PMID 9349523. doi:10.1046/j.1471-4159.1997.69051810.x.. ...
Biogenic amines: Monoamines: 6-OHM. *Dopamine. *Epinephrine (adrenaline). *NAS (normelatonin). *Norepinephrine (noradrenaline) ... Vidal, C. R. (28 June 1997). "Highly Excited Triplet States of Carbon Monoxide". Archived from the original on 2006-08-28. ... Lupinetti, Anthony J.; Fau, Stefan; Frenking, Gernot; Strauss, Steven H. (1997). "Theoretical Analysis of the Bonding between ...
The amine on the pyridine is protonated and acts as an electron sink, enabling the breaking of the C-C bond and releasing CO2. ... Protonation of the amine from tryptophan restores the aromaticity of the pyridine ring and then imine is hydrolyzed to produce ... which allows the lone pair on the amine to attack acetyl-CoA, forming a tetrahedral intermediate. The thiol from coenzyme A ... Guardiola-Lemaître B (December 1997). "Toxicology of melatonin". Journal of Biological Rhythms. 12 (6): 697-706. doi:10.1177/ ...
Nucleic acid sequence
Flavin-containing monooxygenase 3
... secondary and tertiary amines whereas human FMO1 is only highly efficient at N-oxygenating tertiary amines. Both human FMO1 and ... For amines with smaller aromatic substituents such as phenethylamines, often these compounds are efficiently N-oxygenated by ... and tertiary amines; the S-oxygenation of nucleophilic sulfur-containing compounds; and the 6-methylhydroxylation of DMXAA. ... including the dietary-derived tertiary amines trimethylamine, tyramine and nicotine; commonly used drugs including cimetidine, ...
... amines, and carboxylic acids where hydrogen bonding occurs. Organic compounds tend to dissolve in organic solvents. Solvents ... Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 0-08-037941-9.. ... Shriner, R.L.; Hermann, C.K.F.; Morrill, T.C.; Curtin, D.Y. and Fuson, R.C. (1997) The Systematic Identification of Organic ...
Heterocyclic amine formation in meat - Wikipedia
Heterocyclic amines are a group of chemical compounds, many of which can be formed during cooking. They are found in meats that ... Recent studies had mixed results, finding no relationship between dietary heterocyclic amines and lung cancer in women who had ... Changes in cooking techniques reduce the level of heterocyclic amines. More than 20 compounds fall into the category of ... In 1977, cancer-causing compounds heterocyclic amines were discovered in food as a result of household cooking processes. The ...
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement | Nature Communications
We identify CXC chemokine receptor 4 (CXCR4) as a receptor used by amines to inhibit pDC. Our study establishes a functional ... Here we show that natural monoamines and synthetic amines inhibit pDC activation by RNA viruses. Furthermore, a synthetic ... Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement. ... link between natural amines and the innate immune system and identifies CXCR4 as a potential on-off switch of pDC activity ...
Cell type specific adhesion to surfaces functionalised by amine plasma polymers | Scientific Reports
Based on all the results, the increased resistance to trypsinization of C2C12, LF, HaCaT, and VSMC cells on amine PPs can be ... on three different amine PPs. We demonstrated the striking difference in the resistance to trypsin treatment between ... proved the difference among the plasma polymers with different amounts of amine groups, but other investigated techniques could ... explained most probably by a non-specific cell adhesion such as electrostatic interaction between the cells and amine groups on ...
Fatty amine - Wikipedia
Commercially important members include coco amine, oleylamine, tallow amine, and soya amine. Some applications of these ... In chemistry, a fatty amine is any amine attached to a hydrocarbon chain of eight or more carbon atoms in length. These ... More commonly fatty amines are derived from C12-C18 hydrocarbons, which in turn are derived from the more abundant fatty acids ... Fatty amines are commonly prepared from fatty acids; which are themselves obtained from natural sources, typically seed-oils. ...
Patent US7511097 - Two-component adhesive of epoxy resins and amine compound - Google Patents
... a second component comprising at least one amine compound with one or more primary and/or secondary amino groups, said amine ... The ratio of the total number of amino groups of the amine compound to the total number of epoxy groups of the epoxy resins is ... b) a second component comprising at least one amine compound with one or more primary and/or secondary amino groups, said amine ... b) a second component comprising at least one amine compound with one or more primary and/or secondary amino groups, said amine ...
Patent US3759807 - Photopolymerization process using combination of organic carbonyls and amines - Google Patents
organic amines can be aliphatic amines and aromatic amines having at least one N-alkyl group, heterocyclic amines, or ... organic amines can be aliphatic amines aromatic amines having at least one N-alkyl group, heterocyclic amines, or combinations ... The preferred organic amines are the tertiary amines with the alkanol amines most preferred. The ... an organic amine activator) produced any polymer; those blends containing -a mixture of the benzophenone plus the organic amine ...
Patent US4359413 - Solid detergent compositions containing alpha-amine oxide surfactants - Google Patents
The alpha-amine oxides have improved stability against metal-catalyzed decomposition in the present compositions. The ... Solid detergent compositions containing alpha-amine oxide surfactants and alkaline materials, which exhibit a pH of greater ... Alpha-Amine Oxide Surfactant. In the general formula for the alpha-amine oxide surfactants herein, R1 can be hydrogen or any C1 ... The instability of the alpha-amine oxides is also partly due to the fact that structurally they are secondary amine oxides (i.e ...
Copper amine oxidase-like, N-terminal domain superfamily (IPR036582) | InterPro | EMBL-EBI
Amine oxidases (AO) are enzymes that catalyse the oxidation of a wide range of biogenic amines including many neurotransmitters ... histamine and xenobiotic amines. There are two classes of amine oxidases: flavin-containing (EC:188.8.131.52) and copper-containing ... The copper amine oxidases occur as mushroom-shaped homodimers of 70-95 kDa, each monomer containing a copper ion and a ... Copper-containing amine oxidases are found in bacteria, fungi, plants and animals. In prokaryotes, the enzyme enables various ...
Patent US2591573 - Resinous insoluble reaction products of tertiary amines with haloalkylated ... - Google Patents
... tricyclohexyl amine, triphenyl amine, diphenyl ethyl amine, benzyl dimethyl amine, benzyl phenyl methyl amine, and the like. ... Suitable tertiary amines are typified by the following: Trimethyl amine, triethyl and tripropyl amines, dimethyl ethyl amine, ... The tertiary amine is used in the form of the free base. Tertiary amines containing unsubstituted hydrocarbon substituents are ... Anion exchange resins from tertiary amines and methyl styrene polymers. US2658042 *. 2 Feb 1952. 3 Nov 1953. Nat Aluminate Corp ...
Patente US4266047 - Novel polymers of olefin terminated prepolymers and amine terminated prepolymers - Google Patentes
... by reacting simple olefins with amine-terminated prepolymers and by reacting olefin-terminated prepolymers with amine- ... by reacting simple olefins with amine-terminated prepolymers and by reacting olefin-terminated prepolymers with amine- ... by reacting simple olefins with amine-terminated prepolymers and by reacting olefin-terminated prepolymers with amine- ... by reacting simple olefins with amine-terminated prepolymers, and by reacting olefin-terminated prepolymers with amine- ...
IUCr) Chloro-(di-ethyl-enetri-amine)copper(II) chloride: a disordered quasi-one-dimensional structure
Chloro-(di-ethyl-enetri-amine)copper(II) chloride: a disordered quasi-one-dimensional structure. ... Farrugia, L. J. (1997). J. Appl. Cryst. 30, 565. CrossRef IUCr Journals Google Scholar. Farrugia, L. J. (1999). J. Appl. Cryst. ... Blessing, R. H. (1997). J. Appl. Cryst. 30, 421-426. CrossRef CAS Web of Science IUCr Journals Google Scholar. Boeyens, J. C. A ... Sheldrick, G. M. (1997). SHELXS97 and SHELXL97. University of Göttingen, Germany. Google Scholar. Towle, D. K., Hoffmann, S. K ...
Bis(di-ethyl-amido-κN)(di-ethyl-amine-κN)bis--(2,6-diiso-propyl-phenyl-amido-κN)zirconium(IV). ... It is caused by the fact, that ligand containing N1 is amine ligand. Difference between length of bonds Zr-N between NEt2 and ... The amine hydrogen atoms were located in the difference Fourier map and refined using a ridnig model with Uiso(H) = 1.2Ueq(N). ... Blake, A. J., Nikonov, G. I. & Mountford, P. (1997). Acta Cryst. C53, 874-876. CSD CrossRef CAS Web of Science IUCr Journals. ...
Heterocyclic amines, cytochrome P4501A2, and N-acetyltransferase: issues involved in incorporating putative genetic...
Algeria: 'Disappearance' / fear for safety: Amine Amrouche | Amnesty International
Amine Amrouche, aged 22, disappeared from his home in Baraki on 30 January 1997. There were no eye-witnesses to his ... Amine Amrouche, aged 22, disappeared from his home in Baraki on 30 January 1997. There were no eye-witnesses to his ... Algeria: Disappearance / fear for safety: Amine Amrouche 17 February 1997. , Index number: MDE 28/002/1997 ...
Molecules | Free Full-Text | Informing Efforts to Develop Nitroreductase for Amine Production | HTML
Amine yields were low, but compounds yielding amines tend to have a large π system and electron withdrawing substituents. ... Several different subgroups of NRs include members able to produce aromatic amines. Comparison of four NR subgroups shows that ... enzymes for development for biocatalysis in prodrug activation and conversion of nitroaromatics to valuable aromatic amines. We ... hold promise for converting nitroaromatics to aromatic amines. Nitroaromatic reduction rate increases with Hammett substituent ...
Diffusion coefficient of water in triethyl-amine | SpringerLink
This chapter provides the diffusion coefficient of water in triethyl-amine at different concentrations measured using Rayleigh ... Winkelmann J. (2018) Diffusion coefficient of water in triethyl-amine. In: Lechner M.D. (eds) Diffusion in Gases, Liquids and ... This chapter provides the diffusion coefficient of water in triethyl-amine at different concentrations measured using Rayleigh ...
Biogenic amine production by the wine Lactobacillus brevis IOEB 9809 in systems that partially mimic the gastrointestinal tract...
Ingestion of fermented foods containing high levels of biogenic amines (BA) can be deleterious to human health. Less obvious is ... Biogenic amines (BA) are natural toxins that can occur in fermented foods and beverages and may cause adverse health effects [1 ... Biogenic amine production by the wine Lactobacillus brevis IOEB 9809 in systems that partially mimic the gastrointestinal tract ... AR and MF carried out the biogenic amines detection and quantification and performed the statistical analysis. PFP set up the ...
Fluoride Action Network | Contact dermatitis and stomatitis due to amine fluoride
... we used the same concentration of amine fluoride as was present in the gel (3.724% aq.), which contains the 2 amine fluorides ... Contact dermatitis and stomatitis due to amine fluoride. Author: Ganter G, Disch R, Borelli S, Simon D. ... Only component A, which was decoded as amine fluoride, showed a strongly positive reaction (++ at D1, +++ at D2 and D3). For ... Furthermore, 5 healthy control subjects did not show any reaction to amine fluoride at this dilution. ...
Extraction Efficiency of Different Solvents and LC-UV Determination of Biogenic Amines in Tea Leaves and Infusions
... such as biogenic amines (BAs) which are nonvolatile amines formed by decarboxylation of amino acids. Natural polyamines are ... formation pathway of biogenic amines [8-10]. As the consumption of food containing large amounts of these amines can have ... underlining that the extraction efficiency varies widely among amines and is affected by the levels of amines in the matrix, ... An individual standard solution of about 1.0 mg mL−1 of each amine was prepared in purified water and stored in darkness at °C ...
Drosophila ABC transporter mutants white, brown and scarlet have altered contents and distribution of biogenic amines in the...
The reduced content of biogenic amines, and the altered distribution of these amines in the heads of white, brown and scarlet ... The amine levels in wild-type fly heads obviously vary, and this may also be true within mutant lines. Thus, our results for ... Differences in the amine phenotype of each mutant are related to those for eye pigment granules. Thus white and brown flies ... white, brown and scarlet mutants have reduced head contents of biogenic amines. The histamine content of white heads was 1.06 ...
Relative Validity of a Food Frequency Questionnaire with a Meat-Cooking and Heterocyclic Amine Module. Marie Cantwell, Beth ... Norrish A. E., Ferguson L. R., Knize M. G., Felton J. S., Sharpe S. J., Jackson R. T. Heterocyclic amine content of cooked meat ... Sinha R., Knize M. G., Salmon C. P., Brown E. D., Rhodes D., Felton J. S., Levander O. A., Rothman N. Heterocyclic amine ... Knize M. G., Brown E. D., Salmon C. P., Levander O. A., Felton J. S., Rothman N. Heterocyclic amine content in restaurant- ...
Method of Making an Amine Containing Biocidal Composition | Southwest Research Institute
The mixture is exposed to chlorine dioxide which reacts with the amine to form iminium chlorite within the hydrophilic ... A process for preparing a composite including mixing a hydrophilic material containing an amine with a hydrophobic material ... The mixture is exposed to chlorine dioxide which reacts with the amine to form iminium chlorite within the hydrophilic material ... A process for preparing a composite including mixing a hydrophilic material containing an amine with a hydrophobic material ...
A weak cation-exchange phase for the separation of biogenic amines by open tubular liquid chromatography
Modafinil Occupies Dopamine and Norepinephrine Transporters in Vivo and Modulates the Transporters and Trace Amine Activity in...
2001) Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci USA 98: 8966-8971. ... The trace amine PEA promotes dopamine release via the DAT (Sotnikova et al., 2004), an effect potentially linked to its ... Miller GM, Verrico CD, Jassen A, Konar M, Yang H, Panas H, Bahn M, Johnson R, and Madras BK (2005) Primate trace amine receptor ... Goulet M, Miller GM, Bendor J, Liu S, Meltzer PC, and Madras BK (2001) Nonamines, drugs without an amine nitrogen, potently ...
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine - Wikipedia
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is one of the most abundant heterocyclic amines (HCAs) in cooked meat. ... 1998) Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat ... 1998) Heterocyclic amine content of pork products cooked by different methods and to varying degrees of doneness. Food Chem ... Heterocyclic amine content of cooked meat and risk of prostate cancer. J. Natl. Cancer Inst. 91, 2038-2044. ...
Poly(Ester Amine)-Mediated, Aerosol-Delivered Akt1 Small Interfering RNA Suppresses Lung Tumorigenesis - Redorbit
Poly(ester amine) was synthesized as described in our previous work. The poly(ester amine)/siRNA complex at a charge ratio of ... Methods: Nanosized poly(ester amine) polymer was synthesized and used as a gene carrier. An aerosol of poly(ester amine)/Akt1 ... ester amine)/siRNA complex was initiated in distilled water by adding 1 mg of plasmid DNA to poly(ester amine), drop by drop, ... Poly(ester amine) carrier may serve as an effective carrier, and aerosol delivery of Akt1 small interfering RNA may be a ...
Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation...
Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange ... Improving B0 correction for pH-weighted amine proton chemical exchange saturation transfer (CEST) imaging by use of K-means ... Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation ... Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange ...
UNdata | record view | Amine-function compounds
Copper Amine Oxidase Expression in Defense Responses to Wounding and Ascochyta rabiei Invasion | Plant Physiology
Copper amine oxidase (CuAO; EC 184.108.40.206) catalyzes the oxidative deamination of various biological active amines with the ... Copper Amine Oxidase Expression in Defense Responses to Wounding and Ascochyta rabiei Invasion Giuseppina Rea, Ouissal Metoui, ... Wounding chickpea (Cicer arietinum) internodes or cotyledons resulted in an increase in the steady-state level of copper amine ... Inhibition is because of the aldehyde oxidation product rather than the short chain amine itself. In fact, the aldehyde ...
Frontiers | Vaginal biogenic amines: biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis? | Physiology
This odor has been associated with increases in several biogenic amines (BAs) that may serve as important biomarkers. Within ... This odor has been associated with increases in several biogenic amines (BAs) that may serve as important biomarkers. Within ... Determining Biogenic Amine Levels Corresponding to CSTs. Sample Set for Measuring Biogenic Amine Levels. Analyses were ... Figure 1. Biogenic amine synthesis pathways in bacteria. The dominant biogenic amine (BA) synthesis pathways involving the ...
Tertiary1996Aromatic Amines and Mycotoxins2001Biogenic amine receptorsHeterocyclic aromatic aminesCarcinogens1998Active aminesNeurotransmittersCarcinogenicColorectalSubstratesBiomarkers1994CopperDerivativesNeuronsAmino acidsDeterminationPolymersConcentrationCytochromeFormation in meatSerotoninAldehydesPolyamineAmmoniaEnzymesReceptorNitrogenInvention relatesTransportersMethodsIntakeCyclizationHydrophobicOrganic
- RCN + 2 H2 → RCH2NH2 In the absence of ammonia, secondary and tertiary amines are produced. (wikipedia.org)
- 2 RCN + 4 H2 → (RCH2)2NH + NH3 3 RCN + 6 H2 → (RCH2)3N + 2 NH3 Alternatively, secondary and tertiary fatty amines can be generated directly from the reaction of fatty alcohols with alkylamines. (wikipedia.org)
- These tertiary amines are precursors to quaternary ammonium salts using for a variety of applications. (wikipedia.org)
- meta-, and para-ethyl styrenes, vinyl naphtha- The resins of this invention are the reaction lene, vinyl anthracene, and the homologues of products of a tertiary amine and an insoluble, the above. (google.com.au)
- RNH 2 (primary amines), R 2 NH (secondary amines), R 3 N (tertiary amines). (iupac.org)
- The present invention relates to a personal care product containing a mixture of at least one personal care ingredient and one diester quaternary ammonium compound with a pH between 4.0 and 10.0 and a viscosity between 100 and 300,000 cps, and the method of making the personal care product diester tertiary amines and quats are also described. (google.es)
- Hydrogen peroxide formation by reaction of peroxynitrite with HEPES and related tertiary amines. (semanticscholar.org)
Aromatic Amines and Mycotoxins1
Biogenic amine receptors3
- Seventeen putative biogenic amine receptors have been identified based on sequence similarity to mammalian receptors, and mutants for most of these are available (see Table 2 ). (wormbook.org)
- Finally, a variety of drugs that target biogenic amine receptors are available and their effects on behavior can be helpful in determining the physiological roles of the receptors (see Table 3 ). (wormbook.org)
- Because of its simplicity and experimental accessibility, cockroach salivary glands have been used extensively as a model system to study the cellular actions of biogenic amines and to examine the pharmacological properties of biogenic amine receptors. (docme.ru)
Heterocyclic aromatic amines2
- The U.S. Department of Health and Human Services Public Health Service labeled several heterocyclic amines as likely carcinogens in its 13th Report on Carcinogens. (wikipedia.org)
- Objective Heterocyclic amines (HAA) are animal carcinogens that are present in meat cooked at high temperature and in tobacco smoke. (bmj.com)
- Many chemicals are thought to be carcinogens for BC, including aniline dyes and aromatic amines ( Vineis and Pirastu, 1997 ). (frontiersin.org)
- Heterocyclic amines are mutagenic and are classified as carcinogens. (naturalmedicinejournal.com)
- Amine oxidases (AO) are enzymes that catalyse the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. (ebi.ac.uk)
- Analysis of the phenotypes of such mutants has shed light on the behaviors controlled by the amines and detailed analysis of the expression patterns of the biosynthetic enzymes and transporter has helped identify the cells and neurons in which the neurotransmitters are made and released (see Table 1 ). (wormbook.org)
- Biogenic amines such as serotonin and norepinephrine are well known as neurotransmitters in the control and regulation of many brain functions, and have been strongly implicated in several pathological conditions such as aggressive and predatory behavior, migraine, depression and carcinoid syndrome. (nii.ac.jp)
- A case-control study was conducted in Uruguay, in order to investigate the relationship between heterocyclic amine intake and colorectal cancer risk. (spandidos-publications.com)
- Heterocyclic amines were associated with a significant increase in the risk of colorectal cancer in males and females. (spandidos-publications.com)
- This latter finding suggests that heterocyclic amine exposure is central in colorectal carcinogenesis. (spandidos-publications.com)
- RCOOH + NH3 → RC≡N + 2 H2O The fatty amine is obtained from this by hydrogenation with any of a number of reagents, including Raney nickel or cobalt, and copper chromite catalysts. (wikipedia.org)
- There are two classes of amine oxidases: flavin-containing ( EC:220.127.116.11 ) and copper-containing ( EC:18.104.22.168 ). (ebi.ac.uk)
- Copper-containing amine oxidases are found in bacteria, fungi, plants and animals. (ebi.ac.uk)
- The copper amine oxidases occur as mushroom-shaped homodimers of 70-95 kDa, each monomer containing a copper ion and a covalently bound redox cofactor, topaquinone (TPQ). (ebi.ac.uk)
- The catalytic domain is the largest of the 3-4 domains found in copper amine oxidases, and consists of a beta sandwich of 18 strands in two sheets. (ebi.ac.uk)
- This entry represents a domain superfamily found at the N-terminal of certain copper amine oxidases, as well as in related proteins such as cell wall hydrolase and N-acetylmuramoyl-L-alanine amidase. (ebi.ac.uk)
- Peroxidase-catalyzed free radical polymerization of phenol, aromatic amines, and their derivatives is well known. (google.com)
- The benzylamine derivatives of the amines could be separated within 15 minon a reverserd-phase microbore column with isocratic elution. (nii.ac.jp)
- In this paper, a novel series of bis [(aminoethyl)]-amine cationic lipid derivatives have been synthesized and identified to purity by NMR and Elemental analysis. (scirp.org)
- To this end, a new series of novel cationic lipid derivatives containing bis[(aminoethyl)]-amine headgroup at the 2-position and hydrophobic chains at the 1- and 3-position, have been synthesized by acylation of a 1,3-di- amino-2-propanol backbone using, dilauroyl, dimyristoyl, dipalmitoyl, distearoyl and dioleoyl acyl chlorides. (scirp.org)
- To examine the potential release of D -Ser and other D -amino acids from islets, a chiral micellar electrokinetic chromatography method was developed by derivatizing primary amines with 2,3-naphthalenedicarboxaldehyde and to achieve resolution of the enantiomers, two surfactants were used in the separation, sodium dodecyl sulfate and sodium deoxycholate. (rsc.org)
- The main mechanism of biogenic formation is the decarboxylation of free amino acids by specific enzymes of microbial origin, which leads to the production of amines. (asmscience.org)
- The concentration of available free amino acids plays a fundamental role in the formation of amines in foods, in that they are their precursors and, moreover, constitute a substrate for microbial growth. (asmscience.org)
- 1991. Quantitative changes in bacteria, amino acids and biogenic amines in sardine (Sardina pilchardus) stored at ambient temperature (25-28°C) and in ice. (asmscience.org)
- In this study, we have developed a microbore high-performance liquid chromatographic method based on precolumn fluorescence derivatization with benzylamine for the determination of the amines in microdialysate from rat brain. (nii.ac.jp)
- This chapter discusses the formation and degradation of biogenic amines, their occurrence in foods, their significance in food safety, their potential use as quality indicators, and the available methods for their determination. (asmscience.org)
- 1993. Liquid chromatographic determination of biogenic amines in dry sausages. (koreascience.or.kr)
- Our previously-obtained impressive results of highly increased C2C12 mouse myoblast adhesion to amine plasma polymers (PPs) motivated current detailed studies of cell resistance to trypsinization, cell proliferation, motility, and the rate of attachment carried out for fibroblasts (LF), keratinocytes (HaCaT), rat vascular smooth muscle cells (VSMC), and endothelial cells (HUVEC, HSVEC, and CPAE) on three different amine PPs. (nature.com)
- This method, as well as the cell attachment rate, proved the difference among the plasma polymers with different amounts of amine groups, but other investigated techniques could not reveal the differences in the cell behaviour on different amine PPs. (nature.com)
- New and useful polymers are prepared by reacting olefin-terminated prepolymeric materials with simple polyamine, by reacting simple olefins with amine-terminated prepolymers and by reacting olefin-terminated prepolymers with amine-terminated prepolymers. (google.es)
- Solid detergent compositions containing alpha-amine oxide surfactants and alkaline materials, which exhibit a pH of greater than 9.0 at a concentration of 1% by weight in water, are disclosed. (google.com)
- For patch testing, we used the same concentration of amine fluoride as was present in the gel (3.724% aq. (fluoridealert.org)
- The effects of increased potassium ion concentration in the Ringer solution and a single intraperitoneal injection of methanphetamine on the amine levels in microdialysate were examined. (nii.ac.jp)
Formation in meat1
- These complementary properties make NRs exceptionally promising enzymes for development for biocatalysis in prodrug activation and conversion of nitroaromatics to valuable aromatic amines. (mdpi.com)
- A variety of experimental approaches including genetic, imaging, biochemical and pharmacological analyses have been used to identify the enzymes and cells that make and release the amines and the cells and receptors that bind them. (wormbook.org)
- A diverse superfamily of enzymes with ATP-dependent carboxylate-amine/thiol ligase activity. (ebi.ac.uk)
- We identify CXC chemokine receptor 4 (CXCR4) as a receptor used by amines to inhibit pDC. (nature.com)
- Based on all the results, the increased resistance to trypsinization of C2C12, LF, HaCaT, and VSMC cells on amine PPs can be explained most probably by a non-specific cell adhesion such as electrostatic interaction between the cells and amine groups on the material surface, rather than by the receptor-mediated adhesion through serum-derived proteins adsorbed on the PPs. (nature.com)
- in vitro, we determined modafinil activity at the DAT, NET, SERT, and rhesus monkey trace amine receptor 1 (TA1). (aspetjournals.org)
- Although the specific biogenic amine that activates a given receptor homolog cannot be accurately predicted based purely on sequence analysis, in a growing number of cases pharmacological analysis of cloned C. elegans receptors has been used to determine their likely physiological ligands (see Table 2 ). (wormbook.org)
- The present invention relates to a two-component epoxy adhesive composition comprising a) a first component comprising a first epoxy resin and a second epoxy resin, the second epoxy resin being flexibilized by an elastomer, and b) a second component comprising at least one amine compound with one or. (google.com)
- InBr3-Catalyzed Cyclization of Glycals with Aryl Amines. (docme.ru)
- Glycal Cyclization InBr3-Catalyzed Cyclization of Glycals with Aryl Amines** Jhillu S. Yadav,* Basi V. S. Reddy, Katta V. Rao, Kavuda Saritha Raj, Atlaluri R. Prasad, Singarapu Kiran Kumar, Ajit C. Kunwar, Panjula Jayaprakash, and Bulusu Jagannath Scheme 1. (docme.ru)