Ovum: A mature haploid female germ cell extruded from the OVARY at OVULATION.Ovalbumin: An albumin obtained from the white of eggs. It is a member of the serpin superfamily.Ovum Transport: Transport of the OVUM or fertilized ovum (ZYGOTE) from the mammalian oviduct (FALLOPIAN TUBES) to the site of EMBRYO IMPLANTATION in the UTERUS.Immunoglobulin E: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Allergens: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.Respiratory Hypersensitivity: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.Antigens: Substances that are recognized by the immune system and induce an immune reaction.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Th2 Cells: Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Eosinophils: Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.Pulmonary Eosinophilia: A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.Superovulation: Occurrence or induction of release of more ova than are normally released at the same time in a given species. The term applies to both animals and humans.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Immune Tolerance: The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.Adjuvants, Immunologic: Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.Ovulation: The discharge of an OVUM from a rupturing follicle in the OVARY.Antigen Presentation: The process by which antigen is presented to lymphocytes in a form they can recognize. This is performed by antigen presenting cells (APCs). Some antigens require processing before they can be recognized. Antigen processing consists of ingestion and partial digestion of the antigen by the APC, followed by presentation of fragments on the cell surface. (From Rosen et al., Dictionary of Immunology, 1989)Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Dendritic Cells: Specialized cells of the hematopoietic system that have branch-like extensions. They are found throughout the lymphatic system, and in non-lymphoid tissues such as SKIN and the epithelia of the intestinal, respiratory, and reproductive tracts. They trap and process ANTIGENS, and present them to T-CELLS, thereby stimulating CELL-MEDIATED IMMUNITY. They are different from the non-hematopoietic FOLLICULAR DENDRITIC CELLS, which have a similar morphology and immune system function, but with respect to humoral immunity (ANTIBODY PRODUCTION).Mucus: The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.Immunization: Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).Interleukin-5: A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Fallopian Tubes: A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.Fertilization: The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Methacholine Chloride: A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)Lymphocyte Activation: Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.Adoptive Transfer: Form of passive immunization where previously sensitized immunologic agents (cells or serum) are transferred to non-immune recipients. When transfer of cells is used as a therapy for the treatment of neoplasms, it is called adoptive immunotherapy (IMMUNOTHERAPY, ADOPTIVE).CD8-Positive T-Lymphocytes: A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Cross-Priming: Class I-restricted activation of CD8-POSITIVE LYMPHOCYTES resulting from ANTIGEN PRESENTATION of exogenous ANTIGENS (cross-presentation). This is in contrast to normal activation of these lymphocytes (direct-priming) which results from presentation of endogenous antigens.Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.Alum Compounds: Aluminum metal sulfate compounds used medically as astringents and for many industrial purposes. They are used in veterinary medicine for the treatment of ulcerative stomatitis, leukorrhea, conjunctivitis, pharyngitis, metritis, and minor wounds.CD4-Positive T-Lymphocytes: A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Interleukin-4: A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.Administration, Intranasal: Delivery of medications through the nasal mucosa.Food Hypersensitivity: Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.Goblet Cells: A glandular epithelial cell or a unicellular gland. Goblet cells secrete MUCUS. They are scattered in the epithelial linings of many organs, especially the SMALL INTESTINE and the RESPIRATORY TRACT.Spleen: An encapsulated lymphatic organ through which venous blood filters.Rats, Inbred BNTh1 Cells: Subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.Interleukin-13: A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.Antigen-Presenting Cells: A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.Fertilization in Vitro: An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.Interferon-gamma: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.Lymph Nodes: They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.Hypersensitivity, Delayed: An increased reactivity to specific antigens mediated not by antibodies but by cells.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Injections, Intraperitoneal: Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Toxascaris: An ascarid nematode found primarily in the small intestine of the larger Felidae as well as dogs and cats. It differs from TOXOCARA in that the larvae do not migrate through the lungs. It does occasionally produce visceral larva migrans (LARVA MIGRANS, VISCERAL) in man, although more rarely than does Toxocara.Oviducts: Ducts that serve exclusively for the passage of eggs from the ovaries to the exterior of the body. In non-mammals, they are termed oviducts. In mammals, they are highly specialized and known as FALLOPIAN TUBES.Bronchoconstrictor Agents: Agents causing the narrowing of the lumen of a bronchus or bronchiole.Epitopes, T-Lymphocyte: Antigenic determinants recognized and bound by the T-cell receptor. Epitopes recognized by the T-cell receptor are often located in the inner, unexposed side of the antigen, and become accessible to the T-cell receptors after proteolytic processing of the antigen.Sperm-Ovum Interactions: Interactive processes between the oocyte (OVUM) and the sperm (SPERMATOZOA) including sperm adhesion, ACROSOME REACTION, sperm penetration of the ZONA PELLUCIDA, and events leading to FERTILIZATION.Gonadotropins, Equine: Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies.Pneumonia: Infection of the lung often accompanied by inflammation.T-Lymphocytes, Cytotoxic: Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.Immunity, Mucosal: Nonsusceptibility to the pathogenic effects of foreign microorganisms or antigenic substances as a result of antibody secretions of the mucous membranes. Mucosal epithelia in the gastrointestinal, respiratory, and reproductive tracts produce a form of IgA (IMMUNOGLOBULIN A, SECRETORY) that serves to protect these ports of entry into the body.Oocyte Donation: Transfer of preovulatory oocytes from donor to a suitable host. Oocytes are collected, fertilized in vitro, and transferred to a host that can be human or animal.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Zygote: The fertilized OVUM resulting from the fusion of a male and a female gamete.T-Lymphocytes: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.Egg Proteins: Proteins which are found in eggs (OVA) from any species.Peptide Fragments: Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.Embryo Transfer: The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.Blepharitis: Inflammation of the eyelids.Dose-Response Relationship, Immunologic: A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Ovary: The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.Toxocara: A genus of ascarid nematodes commonly parasitic in the intestines of cats and dogs.ISCOMs: A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines.Spermatozoa: Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.Bronchoconstriction: Narrowing of the caliber of the BRONCHI, physiologically or as a result of pharmacological intervention.Vitelline Membrane: The plasma membrane of the egg.Freund's Adjuvant: An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.Schistosoma haematobium: A species of trematode blood flukes of the family Schistosomatidae which occurs at different stages in development in veins of the pulmonary and hepatic system and finally the bladder lumen. This parasite causes urinary schistosomiasis.Bronchial Provocation Tests: Tests involving inhalation of allergens (nebulized or in dust form), nebulized pharmacologically active solutions (e.g., histamine, methacholine), or control solutions, followed by assessment of respiratory function. These tests are used in the diagnosis of asthma.Airway Resistance: Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.Nasal Mucosa: The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.Insemination, Artificial: Artificial introduction of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.Chorionic Gonadotropin: A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).Antibody Formation: The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.Respiratory System: The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.Intestinal Diseases, Parasitic: Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.Melanoma, Experimental: Experimentally induced tumor that produces MELANIN in animals to provide a model for studying human MELANOMA.Chemokine CCL11: A CC-type chemokine that is specific for CCR3 RECEPTORS. It is a potent chemoattractant for EOSINOPHILS.Aerosols: Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.T-Lymphocyte Subsets: A classification of T-lymphocytes, especially into helper/inducer, suppressor/effector, and cytotoxic subsets, based on structurally or functionally different populations of cells.Mice, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.Injections, Subcutaneous: Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.Schistosomiasis haematobia: A human disease caused by the infection of parasitic worms SCHISTOSOMA HAEMATOBIUM. It is endemic in AFRICA and parts of the MIDDLE EAST. Tissue damages most often occur in the URINARY TRACT, specifically the URINARY BLADDER.Methyl Green: A tri-benzene-ammonium usually compounded with zinc chloride. It is used as a biological stain and for the dyeing and printing of textiles.T-Lymphocytes, Regulatory: CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.Administration, Inhalation: The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.Blastocyst: A post-MORULA preimplantation mammalian embryo that develops from a 32-cell stage into a fluid-filled hollow ball of over a hundred cells. A blastocyst has two distinctive tissues. The outer layer of trophoblasts gives rise to extra-embryonic tissues. The inner cell mass gives rise to the embryonic disc and eventual embryo proper.Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.Ovarian Follicle: An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.Cleavage Stage, Ovum: The earliest developmental stage of a fertilized ovum (ZYGOTE) during which there are several mitotic divisions within the ZONA PELLUCIDA. Each cleavage or segmentation yields two BLASTOMERES of about half size of the parent cell. This cleavage stage generally covers the period up to 16-cell MORULA.Anti-Allergic Agents: Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)Histocompatibility Antigens Class I: Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.Cholera Toxin: An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells, and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.Aluminum Hydroxide: A compound with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc.Th1-Th2 Balance: Homeostatic control of the immune system by secretion of different cytokines by the Th1 and Th2 cells. The concentration dependent binding of the various cytokines to specific receptors determines the balance (or imbalance leading to disease).Desensitization, Immunologic: Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.Uterus: The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.Interleukin-12: A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.Oocytes: Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).Histocompatibility Antigens Class II: Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.Therapy with Helminths: The treatment of immune system diseases by deliberate infestation with helminths. This therapy is partly based on the HYGIENE HYPOTHESIS which states that the absence of parasites increases immune dysregulation because of the lack of stimulation of REGULATORY T-CELLS.Antigens, CD11c: An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Peyer's Patches: Lymphoid tissue on the mucosa of the small intestine.Hypersensitivity, Immediate: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.Thymoma: A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)Vaccines: Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.Cancer Vaccines: Vaccines or candidate vaccines designed to prevent or treat cancer. Vaccines are produced using the patient's own whole tumor cells as the source of antigens, or using tumor-specific antigens, often recombinantly produced.Oocyte Retrieval: Procedures to obtain viable OOCYTES from the host. Oocytes most often are collected by needle aspiration from OVARIAN FOLLICLES before OVULATION.Morula: An early embryo that is a compact mass of about 16 BLASTOMERES. It resembles a cluster of mulberries with two types of cells, outer cells and inner cells. Morula is the stage before BLASTULA in non-mammalian animals or a BLASTOCYST in mammals.Estrus: The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.Cell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Phthalic Anhydrides: Phthalic acid anhydrides. Can be substituted on any carbon atom. Used extensively in industry and as a reagent in the acylation of amino- and hydroxyl groups.Mast Cells: Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.Receptors, Antigen, T-Cell: Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (ANTIGENS, CD3). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.Litter Size: The number of offspring produced at one birth by a viviparous animal.Ascariasis: Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.Respiratory Mucosa: The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.Bronchi: The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.Egg Hypersensitivity: Allergic reaction to eggs that is triggered by the immune system.Skin Diseases, Parasitic: Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.Fertility: The capacity to conceive or to induce conception. It may refer to either the male or female.Immunologic Memory: The altered state of immunologic responsiveness resulting from initial contact with antigen, which enables the individual to produce antibodies more rapidly and in greater quantity in response to secondary antigenic stimulus.T-Lymphocytes, Helper-Inducer: Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.Intestinal Mucosa: Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Salpingectomy: Excision of one or both of the FALLOPIAN TUBES.Time Factors: Elements of limited time intervals, contributing to particular results or situations.ShrewsOvulation Induction: Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.Feces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Chickens: Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.Epitopes: Sites on an antigen that interact with specific antibodies.Immunity, Cellular: Manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place in the absence of circulating antibody or where antibody plays a subordinate role.Interleukin-10: A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.Embryonic and Fetal Development: Morphological and physiological development of EMBRYOS or FETUSES.Administration, Cutaneous: The application of suitable drug dosage forms to the skin for either local or systemic effects.Zona Pellucida: A tough transparent membrane surrounding the OVUM. It is penetrated by the sperm during FERTILIZATION.Immunity, Humoral: Antibody-mediated immune response. Humoral immunity is brought about by ANTIBODY FORMATION, resulting from TH2 CELLS activating B-LYMPHOCYTES, followed by COMPLEMENT ACTIVATION.Passive Cutaneous Anaphylaxis: An evanescent cutaneous reaction occurring when antibody is injected into a local area on the skin and antigen is subsequently injected intravenously along with a dye. The dye makes the rapidly occurring capillary dilatation and increased vascular permeability readily visible by leakage into the reaction site. PCA is a sensitive reaction for detecting very small quantities of antibodies and is also a method for studying the mechanisms of immediate hypersensitivity.B-Lymphocytes: Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.Antigens, CD8: Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. CD8 antigens are members of the immunoglobulin supergene family and are associative recognition elements in MHC (Major Histocompatibility Complex) Class I-restricted interactions.Antigens, CD80: A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.Cytotoxicity, Immunologic: The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.Sanitary Engineering: A branch of engineering concerned with the design, construction, and maintenance of environmental facilities conducive to public health, such as water supply and waste disposal.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Haptens: Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.Leukotriene Antagonists: A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.H-2 Antigens: The major group of transplantation antigens in the mouse.Helminths: Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.Gonadotropins: Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Chemokines, CC: Group of chemokines with adjacent cysteines that are chemoattractants for lymphocytes, monocytes, eosinophils, basophils but not neutrophils.Immunotherapy, Adoptive: Form of adoptive transfer where cells with antitumor activity are transferred to the tumor-bearing host in order to mediate tumor regression. The lymphoid cells commonly used are lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL). This is usually considered a form of passive immunotherapy. (From DeVita, et al., Cancer, 1993, pp.305-7, 314)ConjunctivitisGATA3 Transcription Factor: A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.Necator: A genus of intestinal parasite worms which includes one of the most important hookworms of man, NECATOR AMERICANUS. The only other known species, N. suillus, has been recovered from pigs.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Bronchoalveolar Lavage: Washing out of the lungs with saline or mucolytic agents for diagnostic or therapeutic purposes. It is very useful in the diagnosis of diffuse pulmonary infiltrates in immunosuppressed patients.Anti-Asthmatic Agents: Drugs that are used to treat asthma.Ascaris: A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.Anterior Chamber: The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)Immunoglobulin A: Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.Embryo Implantation: Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.Specific Pathogen-Free Organisms: Animals or humans raised in the absence of a particular disease-causing virus or other microorganism. Less frequently plants are cultivated pathogen-free.Mice, Mutant Strains: Mice bearing mutant genes which are phenotypically expressed in the animals.Schistosomiasis mansoni: Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.Autoantigens: Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.Follicular Fluid: The fluid surrounding the OVUM and GRANULOSA CELLS in the Graafian follicle (OVARIAN FOLLICLE). The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes.Interleukin-2 Receptor alpha Subunit: A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-2.Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.Forkhead Transcription Factors: A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.Chemokines: Class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They can be divided into at least three structural branches: C; (CHEMOKINES, C); CC; (CHEMOKINES, CC); and CXC; (CHEMOKINES, CXC); according to variations in a shared cysteine motif.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Conalbumin: A glycoprotein albumin from hen's egg white with strong iron-binding affinity.Sperm Transport: Passive or active movement of SPERMATOZOA from the testicular SEMINIFEROUS TUBULES through the male reproductive tract as well as within the female reproductive tract.Antigens, Neoplasm: Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.Parasitic Diseases: Infections or infestations with parasitic organisms. They are often contracted through contact with an intermediate vector, but may occur as the result of direct exposure.Immunophenotyping: Process of classifying cells of the immune system based on structural and functional differences. The process is commonly used to analyze and sort T-lymphocytes into subsets based on CD antigens by the technique of flow cytometry.Sperm Capacitation: The structural and functional changes by which SPERMATOZOA become capable of oocyte FERTILIZATION. It normally requires exposing the sperm to the female genital tract for a period of time to bring about increased SPERM MOTILITY and the ACROSOME REACTION before fertilization in the FALLOPIAN TUBES can take place.Conservation of Energy Resources: Planned management, use, and preservation of energy resources.
Ovum Testamentum (Vol. 74), 1994. "Judaism at Sardis," in A. R. Seager et al. The Synagogue and Its Setting. Archaeological ...
Z-Knights OVA (1991; mechanical design and mechanic animation director) Gekkō no Piasu Yumemi to Gin no Bara Kishidan (1991; ... 1994; mechanical design) Street Fighter II: The Animated Movie (1994; visual effect) Street Fighter II V (1995; visual effect) ...
Two of the series, Burn Up W (an OVA in 4 parts) and Burn Up Excess (13 parts) form a mostly united story arc. Many of the ... An English dub of the OVA was produced in 1994 by ADV Films, and was released on VHS that year. In 2005, ADV Films released the ... In 2009, Sentai Filmworks re-released the OVA on DVD. Police Officers Maki, Reimi and Yuka are stuck on traffic patrol when ... OVA on DVD. The DVD also contains the English dub. ...
It was published in Japan as a one-shot OVA. The anime original video animation was first released in North America on VHS by ... In a short mini-series of comics that followed the OVA, this tendency to use action and adventure mostly as a vehicle for ... ADV Films, on July 20, 1994. ADV announced that the anime would be a second release on DVD on February 5, 2002. Like much of ...
An OVA adaptation was released in 1994. Midori Saejima is a first-year student at the newly established Hijiri Gakuen. Midori ...
OVA/ONA. *Dallos (1983-1984). *Creamy Mami, the Magic Angel: Eien no Once More (1984) ...
OVA and anime movies Dead Heat (1987; producer) Mobile Suit Gundam: Char's Counterattack (1988; producer) Mobile Suit SD Gundam ... 1991-1994; producer) Zettai Muteki Raijin-Oh (絶対無敵ライジンオー, Zettai Muteki Raijinō) 1991 Genki Bakuhatsu Ganbaruger (元気爆発ガンバルガー, ...
It makes use of zona-free hamster egg, which resembles human ovum. A normal sperm is capable of penetrating the egg, showing ... Sperm-Cervical mucus contact test Kurzrock-Miller test Postcoital test Mortimer, David (1994). Practical laboratory andrology. ...
In the second OVA, he sends an attack on the country Karain by making the overall decision. In the third OVA, Genichiro has ... as it features many victims being brutally dismembered and disemboweled throughout the OVA. In the first OVA, the masked ... In the second OVA, Elaine is named "Laura" by a young doctor, Myra, who once had a daughter about that age but died in a plane ... In the third OVA, Elaine appears much as in a dormant state, confined to her dream-like world with her older sister, Diana. It ...
The OVA is licensed in United States by Media Blasters. Fujimi Shobo published the manga's six tankōbon between January 1994 ... Detatoko Princess (manga) at Anime News Network's encyclopedia Detatoko Princess (OVA) at Anime News Network's encyclopedia. ... "Suddenly Princess") is a Japanese manga written by Hitoshi Okuda and serialised in Dragon Magazine from 1994 to 1999. The ...
Watt, Morris N. (1 January 1913). "Ova of some of the Lepidoptera of the New Zealand". Transactions and proceedings of the New ... Dugdale, J. S. (1994). "Hepialidae (Insecta: Lepidoptera)" (PDF). Fauna of New Zealand. 30: 69-70. Retrieved 24 October 2016. ...
In June 1998, the sixth and final episodes of the OVA were released. In October 1998, the Saber Marionette J to X TV series was ... The Saber Marionette J TV series, the Saber Marionette J Again OVA, and the Saber Marionette J to X TV series are currently ... Originally, the SMZ was intended to be the OVA sequel for Saber Marionette R, but it never materialized, only a manga was made ... In October 1997, a sequel arrived on video, the Saber Marionette J Again OVA. ...
This was followed by a three-episode anime original video animation (OVA) in 1995. Produced by Madhouse and Studio Deen, the ... DNA² (manga) at Anime News Network's encyclopedia DNA² (anime) at Anime News Network's encyclopedia DNA² (OVA) at Anime News ... Dragon Half OVA, Fatal Fury Specials". Anime News Network. Retrieved 10 November 2013. "Finalists for the American Anime Awards ... 36 through 1994 No. 29 and consists of 42 chapters collected in 5 tankōbon volumes: "Discotek Adds DNA2, 1st Lupin III TV ...
Ojisan (おじさん, Ojisan, "Uncle") Voiced by: Mikio Terashima (OVA 1), Shōzō Iizuka (OVA 2) A middle-aged man with a perpetual grin ... Takahiro (タカヒロ) Voiced by: Akio Suyama (OVA 1), Toshiyuki Toyonaga (OVA 2) The grandson of Ojisan, who lives with his ... The first OVA series, produced by Ajia-do Animation Works and directed by Takashi Annō, was released in May 1998 and December ... "OVA·ヨコハマ買い出し紀行 -Quiet Country Cafe- 公式Webサイト" (in Japanese). Sony Music. Retrieved 27 January 2009. Dirk Deppey. "A Comics ...
The OVA series is based on sections of the first two volumes. There were originally going to be 4 OVA episodes but there was ... The first OVA, Dragon Half: Mink's Journey (ドラゴンハーフ~ミンク旅立ち, Doragon Hāfu: Minku Tabidachi), was released on March 26, 1993. The ... It was adapted into a two episode anime OVA series in 1993. ADV Films had previously licensed the anime series in North America ... A two-volume anime OVA adaptation was produced by Victor Entertainment. It was directed and written by Shin'ya Sadamitsu, with ...
The OVA was released on DVD between July 31 and September 25, 2001. The series was released as a digitally remastered thinkpak ... The OVA was a 10-part series released between October 1, 1994 and August 1, 1996. All episodes were directed between Mashimo ... They, along with the rest of the soundtrack for both the TV series and OVA were released by AnimeTrax on June 5, 2001. The TV ... The Irresponsible Captain Tylor anime and OVA series is based on The Most Irresponsible Man in Space series of light novels by ...
... Blade II, a 6-episode OVA based on the 1992 anime series, released in 1994. Uchū no Kishi: Tekkaman Blade, a scrolling ...
The series was adapted as a six-part anime original video animation (OVA) in 1993. Both the manga and OVA are licensed for ... It was published by Hakusensha from 1987 to 1994 in Hana to Yume and collected in 21 tankōbon volumes. ...
In 1990, the short story manga collection Nantoka Narudesho! was adapted into an OVA, which mixed anime, live action and ... The less lines the better". In 1994, Eguchi founded Comic Cue, an alternative yearly manga magazine: "I wanted to make ...
An English version of this OVA was later licensed by ADV Films and distributed in North America. Galactic Angel (ACT1 宇宙(あま)翔ける ... Maps (manga) (manga) at Anime News Network's encyclopedia Maps (manga) (OVA) at Anime News Network's encyclopedia IMDB entry ... It was serialized in the Gakken magazine Monthly Comic Nora from 1985 to 1994. The series was adapted into two anime original ... It was serialized in the Gakken magazine Monthly Comic Nora from 1985 to 1994. A total of 17 tankōbon bound volumes were ...
In 1996, Studio Pierrot adapted the manga into a three-episode original video animation (OVA) anime series. When the anime was ... It was serialized in the Shueisha magazine Weekly Young Jump from 1994 to 1997. ...
... (OVA) at Anime News Network's encyclopedia. ... The series was published in 10 volumes between 1990 and 1994. ... 1994. "日本SFファングループ連合会議:星雲賞リスト" [Japan Union Conference SF fan group: Nebula Award List] (in Japanese). SF-Fan. Retrieved 2011- ...
At the end of the SIN OVA, it is shown that Hayato and Asuka were getting married in which all the acquaintances from the Cyber ... Originally, Asuka fully backed up Hayato in the TV series and the Double One OVA, but since the accident met by Hayato in the ... Asuka and Hayato had an engagement in the Zero OVA, but because of Hayato's betrayal of his promise to not race anymore, she ... In the Double One OVA, she is also worried about her brother, driving as Knight Schumacher, who had his eye condition worsened ...
This is a list of albums for the anime OVA series Macross Plus. The series has been described as needing "an extremely strong ... Macross Plus Original Soundtrack II is the second soundtrack for the OVA series. "Idol Talk" by Akino Arai is the opening theme ... Macross Plus Original Soundtrack is the first soundtrack for the OVA series and the sole soundtrack on which vocalist Mai ... All four albums were first released in Japan beginning in October 1994 up through November 1995. Macross Plus Soundtrack and ...
A two-episode OVA was released in 1994, chronicling his exploits in the first volume of the manga. The Rapeman's garb is ... 1994-05-06). "Steve discusses the naming of Big Black and Rapeman". Action Park, quoting Rock Names by Adam Dolgins. Retrieved ...
Ova stranica posljednji je put uređivana dana 24. lipnja 2019. u 17:06. ... Richard J. Roberts i Phillip A. Sharp • 1994. Alfred G. Gilman i Martin Rodbell • 1995. Edward B. Lewis, Christiane Nüsslein- ...
In the OVA, she met him on the rooftop of Idos clinic soon after Ido gave her a new cyborg body. In the manga, they first meet ... In the OVA, she does not do this. Vector is told by Chiren that Yugo was killed by a hunter-warrior then struck by lightning. ... The OVA comprises two episodes, Rusty Angel and Tears Sign, that serve as a compressed preview for the manga. They correspond ... Chiren only appears in the OVA. In the manga, Ido is not shown to have a love interest or woman whom he used to be involved ...
Microscopy and Culture of Stool for Ova and Parasites. Strongyloides larvae are secreted in feces and excretion may be ... Ova are almost never observed during a strongyloidiasis infection unless severe diarrhea occurs; results from this examination ... including several stool examinations for ova and parasites, special larvae detection techniques, and/or serology in all ... All material on this website is protected by copyright, Copyright © 1994-2018 by WebMD LLC. This website also contains material ...
Lanistes ovum. In: IUCN 2011. IUCN Red List of Threatened Species. Version 2011.1. . Downloaded on 26 June 2011. Lanistes Ovum ... Lanistes ovum is a species of freshwater snail with an operculum, an African apple snail, an aquatic gastropod mollusk in the ... http://www.zoologischemededelingen.nl/83/nr03/a04 Lanistes Ovum Archived 2012-05-27 at the Wayback Machine., Zipcodezoo.com.. ... Freshwater Snails of Africa and Their Medical Importance Brown, D. S. (1994). Freshwater Snails of Africa and Their Medical ...
OVA/ONA. *Dallos (1983-1984). *Creamy Mami, the Magic Angel: Eien no Once More (1984) ...
The Ova gene was expressed in Escherichia coli with high yield using the T7 phage promoter; the amount of the recombinant Ova ( ... Biological context of Ovum. *There is evidence showing that the Mos protein is associated with tubulin in unfertilized eggs and ... Analytical, diagnostic and therapeutic context of Ovum. *We also show by gel filtration analyses that eIF4E is present in ... Tetanus toxoid was found to be the most stable in the presence of anhydride monomers, while Ova was most stable in the presence ...
GH is beneficial to the repair of oocytes and quality improvement of ova in older patients because it can upregulate expression ... Endometrial thickness: a predictor of implantation in ovum recipients? Hum Reprod. (1994) 9:363-5. doi: 10.1093/oxfordjournals. ...
Toxocara cati ova were found in 7 (6.3%) samples, 2 had Ascaris lumbricoides ova, 3 had larvae morphologically similar to ... Toxocara ova in soil in the Mosul District, Iraq, and their relevance to public health measures in the Middle East. Annals of ... The burden of T. cati ova during the wet season and the whole year is shown in Table 1. The highest contamination rate was in ... Embryonated ova can remain viable for a considerable length of time in soil [1]. Small children are considered at risk from ...
Ova, Koultek, et al., 2000. Ova, P.V.; Koultek, B.; Hoskovec, M., Practice Oriented Results on Use and Production of Neem ... Ova, Koultek, et al., 2000. Based on data from 373. - 413. K. See also Koutek, Hoskovec, et al., 1994. ... Koutek, Hoskovec, et al., 1994. Koutek, Bohumír; Hoskovec, Michal; Vrkocová, Pavlína; Konecný, Karel; Feltl, Ladislav, Gas ... Alcohols, Journal of Chromatography A, 1994, 679, 2, 307-317, https://doi.org/10.1016/0021-9673(94)80573-3 . [all data] ...
Requests for ova and parasite examination of a stool specimen will often enable identification of Giardia lamblia and Entamoeba ... For cysts, ova, and parasite detection, at least 3 stool samples must be collected. Sometimes the organism may still be missed ... Utility of Multiple-Stool-Specimen Ova and Parasite Examinations in a High-Prevalence Setting. J Clin Microbiol. 1999;37:2408- ... 1994;43:81-89. Dupont HL, Mathewson JJ. Escherichia coli diarrhea. In: Evans AS, Brachman PS, eds. Bacterial Infections of ...
The series was adapted as a six-part anime original video animation (OVA) in 1993. Both the manga and OVA are licensed for ... It was published by Hakusensha from 1987 to 1994 in Hana to Yume and collected in 21 tankōbon volumes. ...
Fasciola gigantica ova. Adult Fasciola gigantica (Looss, 1896) can be obtained from condemned livers of cattle and sheep. Cut ... Tielens, A. G. M. (1994). Energy generation in parasitic helminths. Parasitology Today, 10, 346.CrossRefGoogle Scholar ... Palmiter, R. D. (1994). Regulation of metalothionein genes appears to be mediated by zing-sensitive inhibitors that interacts ... These results could be discussed according to positive and negative gene regulatory mechanism (Palmiter, 1994). Mohamed, Osman ...
No evidence of Toxocara cati ova was found. Only one sample was positive for Toxascaris leonina ova. Over 50% of the T. canis ... Of these samples, 15% were positive for Toxocara canis ova and a mean egg density of 1.4 ova/100 g was calculated. Two types of ... Female T. canis worms with mature ova and those with immature ova differed significantly with regard to their length. The ... Prevalence of Toxocara canis ova in public playgrounds in the Dublin area of Ireland ...
Effect of Lynestrenol on ovum implantation and oviductal morphology in the rat. Fertility and Sterility. 1971; 22: 741-744. ... Endometrial thickness: a predictor of implantation in ovum recipients? Human Reproduction. 1994; 9: 363-365. ... 1994; 83: 29-34.. 36. Croxatto HB, Diaz S, et al. Plasma progesterone levels during long-term treatment with levonorgestrel ... Additional larger and more recent studies [Abdalla et al16, 1994; Dickey et al17, 1993; Gonen et al18, 1989; Schwartz et al19, ...
Post thaw chronology of motility and of zona-free hamster ova penetration. Fertil Steril 47:980-984PubMedGoogle Scholar ... Morse-Gaugio M, Risley MS (1994) Topoisomerase II expression and VM-26 induction of DNA breaks during spermatogenesis in ... Olshan AF, Mattison DR (eds) (1994) Male mediated developmental toxicity. Plenum, New YorkGoogle Scholar ... Cummins JM, Jequier AM, Kan (1994) Molecular biology of human male infertility: links with ageing, mitochondrial genetics and ...
Screening for ova-rian cancer: recommendations and rationale. Ann Intern Med. 1994; 121: 141-142.Google Scholar ... Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA. 1994; 44: 7-26.Google Scholar ... Cancer Facts and Figures-1994. Atlanta: American Cancer Society; 1994.Google Scholar ...
Stream drift, size-selective predation and the evolution of ovum size in an amphibian. Oecologia 71:624-630.. Petranka, J.W., M ... 1994. Automated data-acquisition. Pp. 47-57. In Heyer, W.R., M.A. Donnelly, R.W. McDiarmid, L.-A.C. Hayek and M.S. Foster (Eds ... Palazzo, T.L. 1994. Bagging salamanders. Pp. 250-251. In Thelander, C.G. (Ed.), Life on the Edge. Biosystems Books, Santa Cruz ... Phillips, K. 1994. Tracking the Vanishing Frogs: An Ecological Mystery. St. Martins Press, New York.. Phillips, K.M. 1995. ...
Pregnancy, impending miscarriage, or blighted ovum. 6. Cefotaxime therapy in children. One study found that only 9% to 19% of ... Lancet 391:485539, 1994. Moreover, these techniques can successfully reduce pain and heart rate less than 2 years and older and ...
P. Wassarman and D. F. Albertini, "The mammalian ovum," in The Physiology of Reproduction, E. Knobil and J. Neill, Eds., pp. 79 ... Raven Press, New York, NY, USA, 2nd edition, 1994. View at Google Scholar ...
Endogenous generation and presentation of the OVA peptide/Kb complex to T-cells. J. Immunol. 150: 2724. ... OVA 257-264) or the AFNV8 (MMTV) peptides (Fig. 6⇓, A and B). However, this standard assay is sensitive to the influence of the ... 1994. Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm. Genome 5: 253. ... 1994. LacZ inducible peptide/MHC specific T-hybrids. Int. Immunol. 6: 369. ...
... that expresses Ova (Lm-Ova). After the infection, only very low numbers of Ova/Kb reactive CD8+ T cells were observed in Rip- ... when Lm-Ova-primed Rip-mOva mice were challenged with a second Ova-expressing pathogen, vesicular stomatitis virus (VSV)-Ova, ... The similar functional avidity of OT-3 T cells to Kb/Ova and OT-1 T cells to Kb/T4 suggests that Kb/Ova is the threshold ligand ... 1 E). Reversing the order of infections or challenge of low-dose Lm-Ova-primed mice with a high dose of Lm-Ova did not lead to ...
Milroy, T. H. (1898). The physical and chemical changes taking place in the ova of certain marine teleosteans during maturation ... but he also argued that protein and phosphate levels were elevated in the mature ova. As noted by Alderdice (1988), there is an ... Sire, M. F., Babin, P. J. and Vernier, J. M. (1994). Involvement of the lysosomal system in yolk protein deposit and ... Fagotto, F. and Maxfield, F. R. (1994). Changes in yolk platelet pH during Xenopus laevis development correlate with yolk ...
5578). Ovoviviparous, embryos feeding on yolk sac and other ova produced by the mother (Ref. 50449). With 4 young in a litter, ... Exhibit ovoviparity (aplacental viviparity), with embryos feeding on other ova produced by the mother (oophagy) after the yolk ... 12288). Maximum length for female given in Romanove et.al 1994 (Ref. 44781). Common bycatch of tuna longline fisheries, and ...
Maximum ova diameter of 650 µm was observed in the ripe ovary. Oocyte size increased with the maturation of gonads. Gonado- ... Maximum ova diameter of 650 µm was observed in the ripe ovary. Oocyte size increased with the maturation of gonads. Gonado- ... Maturity of the Californian sardine (Sardina caerulea) determined by ova diameter measurements ...
Egg; best confined to the hen and to cuisine; use oocyte. Ovum; does not exist in human; use oocyte, ootid, embryo. ... 5. Did you know that there is no such thing as a fertilized egg; no such thing as an ovum?. [10]. ... Wilhelm His, Anatomie menschlicher Embryonen (Leipzig: Vogel, 1880-1885); ORahilly and Muller 1994, p. 3; Keith L. Moore and T ... and Muller 1994, p. 30]. ... Similarly, after the appearance of the primitive streak and notochordal process, any attempt at ...
1994, Research Category:Grant-in-Aid for Developmental Scientific Research (B), Research Field:基礎獣医学 ... Publications] Lu R-Z et al: Embryonal development and growth factors : Effect of activin on mouse fertilized ova in vitro. (in ... Completed(Fiscal Year 1994) Budget Amount *help. ¥16,300,000 (Direct Cost : ¥16,300,000). Fiscal Year 1994 : ¥2,600,000 (Direct ... 33-38 (1994). *. Description. 「研究成果報告書概要(和文)」より ...
  • This was followed by a three-episode anime original video animation (OVA) in 1995. (wn.com)
  • The third group consisted of 90 samples obtained between September 1994 and August 1995 from children with diarrhea who were less than 3 years of age and who attended eight different DCCs in Santiago. (asm.org)
  • In patients with an appropriate geographic history, rule out strongyloidiasis by means of thorough evaluation, including several stool examinations for ova and parasites, special larvae detection techniques, and/or serology in all transplant candidates or others who are likely to receive a prolonged course of steroids or other immunosuppressive medications. (medscape.com)
  • Meridian Diagnostics, Inc.), and ova and parasites by direct microscopic observation. (asm.org)
  • Trophozoites, cysts and ova of other parasites identified were illustrated in relation to sex ( Table 2 ) and age ( Table 3 ). (who.int)
  • Artifacts Mimicking Ova and Parasites. (md-medicaldata.com)
  • It was published by Hakusensha from 1987 to 1994 in Hana to Yume and collected in 21 tankōbon volumes. (wikipedia.org)
  • One common and conspicuous feature of free-spawned eggs is an extracellular `accessory' structure that surrounds the ovum and is shed early in development ( Strathmann, 1987 ). (biologists.org)
  • The observations of Milroy (1898) implicated inorganic ions, particularly Cl - , as important osmolytes in the hydration process, but he also argued that protein and phosphate levels were elevated in the mature ova. (biologists.org)
  • Sporocysts (usually elliptical to circular in shape from 16 to 31 μm in diameter) containing up to 30 spherical spores (2 to 3.2 μm in diameter) within the cytoplasm of well developed oocytes and mature ova. (gc.ca)
  • 1994) suggest that numbers of amphibians, including tiger salamanders, on the landscape have decreased more rapidly than has habitat loss, and in portions of the Midwest, EuroAmerican settlement has produced nearly 99% habitat (breeding wetland) loss (Leja, 1998). (amphibiaweb.org)
  • What's really at issue here is how much testing is appropriate to ensure that Plan B does not induce the chemical abortion of a fertilized ovum. (blogspot.com)
  • P. Wassarman and D. F. Albertini, "The mammalian ovum," in The Physiology of Reproduction , E. Knobil and J. Neill, Eds. (hindawi.com)
  • I mentioned to her, that from my understanding, a blighted ovum will not present with a yolk sac, but she said that is not true and blighted ovums can in fact contain a yolk sac. (medhelp.org)
  • Freshwater Snails of Africa and Their Medical Importance Brown, D. S. (1994). (wikipedia.org)
  • Snails found were picked and put in wide mouth plastic buckets and taken to the laboratory where they were screened for Cercariae after exposure to sunlight for about 3hours (Emejulu et al 1994). (ispub.com)
  • Stool samples were collected from 240 children (aged less than five years) with a primary diagnosis of gastroenteritis from March to November 1994. (who.int)
  • Lanistes ovum is a species of freshwater snail with an operculum, an African apple snail, an aquatic gastropod mollusk in the family Ampullariidae. (wikipedia.org)
  • If a fertilized ovum is not implanted, progesterone and estrogen levels decline sharply, resulting in menstrual bleeding. (aafp.org)
  • Further awards followed in 1994 and 1994 when he received the Patrick Steptoe Memorial Medal from the British Fertility Society, and the Benjamin Henry Sheares Medal from the Obstetrical and Gynaecological Society, Singapore. (wikipedia.org)
  • 6 Grobstein's reasoning also became the basis for justifying human embryo research, as proposed by the National Institutes of Health Advisory Committee in 1994. (lifeissues.net)
  • So my question is, 1) Could this be a blighted ovum and 2) How much chance do I have of this pregnancy being viable? (medhelp.org)
  • It's been 4-5 months that I haven't had my period and I've been taking pregnancy test for those few month and it says negative all the time so I'm really worried that what if I won't be pregnant so I took the ova-MIT and I was wondering if it is safe to take the pill. (medhelp.org)
  • Samples were collected and examined by the modified Ziehl-Neelsen method between March and November 1994. (who.int)
  • All samples were also examined microscopically by the direct smear method for the presence of parasitic ova, cysts and trophozoites. (who.int)
  • the ova must undergo a period of development in the environment before they can become infective . (who.int)
  • The organic cost of jelly is a fraction of that of the ovum, providing an efficient means of extending target size beyond the ovum size that is optimal for larval or juvenile development. (biologists.org)
  • i was asked by my doctor to take ova mit for 7 days starting on the day 4 (21 tablet = 3 tablets to be taken altogether) of my menstrual cycle. (medhelp.org)
  • DNA² was adapted into a 12-episode anime television series which ran on Nippon Television from October 7, 1994 to December 23, 1994. (wn.com)
  • The latest revelation that American scientists have created the first babies carrying DNA from a man and two different women, through manipulating a woman's ova, has caused the alarm bells to ring - momentarily - around the world. (newsweekly.com.au)
  • The practice, used to boost the low success rate in IVF by introducing exoplasmic material from a donor woman into the ova of older infertile women. (newsweekly.com.au)
  • The OVA comprises two episodes, Rusty Angel and Tears Sign, that serve as a compressed preview for the manga. (wikipedia.org)
  • Dī En Ei Tsū: Dokoka de Nakushita Aitsu no Aitsu ) is a science fiction manga series written and illustrated by Masakazu Katsura . (wn.com)
  • could affect the viability of the infected ova and possibly reduce fecundity. (gc.ca)
  • Sitting as an en banc court, we consider whether the district court properly enjoined the "operation and effect" of the Louisiana state tort statute at issue, which provides a private cause of action against medical doctors performing abortions. (openjurist.org)
  • The isoboles showed antagonism between daidzein and hesperetin on baseline relaxant effect and OVA (100 μg/ml)-induced contraction in the sensitized guinea-pig trachea. (frontiersin.org)