A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal function. They are used systemically in the free alcohol form, but with esterification of the hydroxy groups, topical effectiveness is increased.
A group of corticosteroids bearing a hydroxy group at the 11-position.
A group of corticosteroids carrying hydroxy groups, usually in the 11- or 17-positions. They comprise the bulk of the corticosteroids used systemically. As they are relatively insoluble in water, salts of various esterified forms are often used for injections or solutions.
Steroids that contain a ketone group at position 17.
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Adrenosympathetic overactivity under conditions of work stress. (1/17)

Serial measurements of urinary adrenaline, noradrenaline, and 11-hydroxycorticosteroid excretion were performed on 32 healthy men under two conditions of work stress; piecework and work on assembly line. A statistically significant increase in adrenaline, noradrenaline, and 11-hydroxycorticosteroids was observed for piecework and assembly line workers compared with salaried and 'ordinary' workers. The results support the assumption that psychosocial factors of an everyday type have significant effects on the sympathoadrenomedullary and adrenocortical function.  (+info)

The factors controlling stem cell recirculation. II. ACTH-induced inhibition of migration of hemopoietic stem cells. (2/17)

Injections of ACTH of prolonged action (twice 1.5 units per mouse) given to lethally (800 R) irradiated mice with a hind limb shielded to the middle of the tibia brought about a twofold decrease in the number of spleen colonies. ACTH injections after sublethal whole-body irradiation (600 R) did not affect the number of endogenous spleen colonies. ACTH injection of normal mice brought about a substantial decrease in the CFU content in the circulating blood at the time of increased 11-hydroxycorticosteroid concentrations in the plasma. The results obtained are interpreted as inhibition of CFU migration from a shielded area of bone marrow induced by a high 11-hydroxycorticosteroid content in the plasma that followed ACTH injections which had no mitostatic effect on CFU proliferation.  (+info)

Adrenal function in 23 children with paracoccidioidomycosis. (3/17)

Adrenal involvement by Paracoccidioides brasiliensis was described at necropsies and in many clinical studies, but only in adults. Therefore, the aim of this study was to evaluate adrenal function in children with paracoccidioidomycosis. Twenty-three children with the systemic form of paracoccidioidomycosis were evaluated and divided in two Groups: Group A (n = 8) included children before treatment and Group B (n = 15) children after the end of treatment. Plasma cortisol (basal and after ACTH test), ACTH, renin activity, aldosterone, sodium and potassium were measured. They were within normal range in all cases, except for renin activity and aldosterone, which were elevated in some cases. Group A patients showed basal and post-ACTH cortisol levels significantly greater than Group B patients. The results showed that adrenal function was not compromised in these children with paracoccidioidomycosis.  (+info)

Cushing's syndrome due to huge adrenocortical multinodular hyperplasia. (4/17)

A case of Cushing's syndrome due to huge adrenocortial multinodular hyperplasia who was shown to be hyperresponsive to ACTH administration, unresponsive to metyrapone administration and resistant to dexamethasone high dose suppression was reported. After two years' duration of his symptoms, the multinodular adrenals weighing 161 g in total were removed by bilateral adrenalectomy which abolished his symptoms. Postoperatively, plasma ACTH rose gradually to above normal levels, suggesting the presence of primary disorder in the hypothalamus-pituitary axis.  (+info)

Precocious development of UDP-glucuronyltransferase activity in chick-embryo liver after administration of adrenocorticotropic hormone and of certain 11beta-hydroxy corticosteroids. (5/17)

1. Precocious development of UDP-glucuronyltransferase (EC 2.4.1.17) and of glucuronidation by endogenous compounds of known chemical composition is reported for the first time. 2. This development occurs precociously in chick-embryo liver after administration to the egg of mammalian adrenocorticotropic hormone, of Synacthen (a synthetic compound possessing adrenocorticotropic activity), or of certain corticosteroids possessing a hydroxy or an oxo group at C-11. 3. Corticosterone-dependent transferase development parallels the rise of infused corticosterone in plasma, but does not require the presence of embryo pituitary in ovo, and is demonstrable in embryo liver explants in vitro. 4. Competence of embryo liver transferase to respond to corticosterone (or dexamethasone) begins over days 13-14, the time of competence to respond to grafted pituitary gland. 5. The transferase appearing after treatment with corticosterone or adrenocorticotropic hormone, like that appearing after pituitary grafting or on natural development and unlike that from the untreated embryo, is markedly activated by membrane-perturbation procedures, suggesting it appears through induction, not activation. 6. Thyroxine and tri-iodothyronine accelerate transferase development after treatment with adrenocorticotropic hormone or corticosteroid to the rate seen after pituitary grafting. 7. A wide range of other hormones and steroids did not obviously influence transferase development in this system. 8. We suggest that grafted pituitary gland evokes precocious transferase development in embryo liver through production of adrenocorticotropic hormone and hence of the active corticosteroids; thyrotropin and thyroxine hasten the process. The role of this mechanism in the natural development of UDP-glucuronyltransferase is discussed.  (+info)

Comparison of corticotrophin and corticosteroid response to lysine vasopressin, insulin, and pyrogen in man. (6/17)

Plasma corticotrophin (ACTH) and corticosteroid levels in response to lysine vasopressin (LVP), insulin hypoglycaemia, and pyrogen have been compared in seven subjects with normal pituitary adrenal function. Intramuscular vasopressin was a weak stimulus to corticotrophin release, peak values lying within the range 49 to 141 pg/ml. Insulin hypoglycaemia consistently caused a more noticeable increase, with peak levels between 114 and 364 pg/ml, while pyrogen was the most powerful, corticotrophin levels rising to between 209 and 1,725 pg/ml. Peak plasma corticosteroid levels showed less pronounced differences between the three tests, and correlated poorly with peak ACTH levels. Thus, relatively small acute changes in corticotrophin levels produce near-maximal adrenal stimulation. Under these conditions, plasma corticosteroid measurements do not accurately reflect circulating corticotrophin levels. These findings help to explain the physiological basis of several observations on the corticosteroid responses to these clinical test procedures.  (+info)

Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone. (7/17)

This study was designed to investigate the possible role of dopaminergic mechanisms in the control of the renin-angiotensin-aldosterone system in normal man. Six normal male subjects in metabolic balance at 150 meq sodium, 60 meq potassium constant intake received the specific dopamine antagonist, metoclopramide, 10 mg i.v. or placebo followed by angiotensin II infusion 1 h later on 2 consecutive days. Metoclopramide increased plasma aldosterone concentration from 8.2+/-2.2 to 21.0+/-3.3 ng/100 ml (P < 0.005) and plasma prolactin concentration from 18.0+/-4.0 to 91.7+/-4.0 ng/ml (P < 0.001) within 15 min of its administration. At 1 h, plasma aldosterone and prolactin concentrations remained elevated at 16.8+/-2.1 ng/100 ml (P < 0.01) and 86.8+/-15.9 ng/ml (P < 0.005), respectively. Angiotensin II at 2, 4, and 6 pmol/kg per min further increased plasma aldosterone concentration to 27.2+/-3.4, 31.9+/-5.7, and 36.0+/-6.7 ng/100 ml (P < 0.02), respectively. Placebo did not alter plasma aldosterone or prolactin concentrations, but angiotensin II increased plasma aldosterone concentration to 13.7+/-2.4, 19.0+/-1.9, and 23.3+/-3.2 ng/100 ml (P < 0.005). The increment of plasma aldosterone concentration in response to angiotensin II was similar after metoclopramide or placebo. The six subjects also received the dopamine agonist, bromocriptine, 2.5 mg or placebo at 6 p.m., midnight, and 6 a.m. followed by angiotensin II infusion on 2 consecutive d. Bromocriptine suppressed prolactin to <3 ng/ml. After placebo, plasma aldosterone concentration increased from 5.2+/-1.4 to 12.3+/-1.7, 17.2+/-2.2, and 21.8+/-3.5 ng/100 ml (P < 0.01) and after bromocriptine from 7.2+/-1.0 to 14.7+/-3.0, 19.8+/-3.2, and 23.4+/-1.6 ng/100 ml (P < 0.001) with each respective angiotensin II dose. No difference in the response to angiotensin II after bromocriptine or placebo was observed. Plasma renin activity, free 11-hydroxycorticoid concentration, and serum potassium concentration were unchanged by metoclopramide or bromocriptine. The results suggest that aldosterone production is under maximum tonic dopaminergic inhibition which can be overridden with stimulation by angiotensin II in normal man.  (+info)

The circadian rhythms of human subjects without timepieces or indication of the alternation of day and night. (8/17)

1. Seven solitary subjects, and two groups of four, spent from 5 to 13 days in an isolation unit without knowledge of time. Three solitary subjects and one group of four adopted fairly regular activity habits with a period of 25-27 h; one subject adopted a period of 30 h, and one of 27 h initially, decreasing to 24-25 h after a few days. One group of four awoke roughly every 24 h, after a sleep which was alternately about 8 h, or about 4 h and believed by the subjects to be an afternoon siesta. Two solitary subjects alternated sleeps of about 8 or 16 h, separated by 24 h of activity.2. Deep temperature in all subjects oscillated with a period of 24-26 h, which was thus commonly distinct from their activity habits.3. Urinary potassium followed a rhythm whose period, though usually close to, was sometimes distinct from, that of temperature. A secondary period corresponding to that of activity was also sometimes present.4. Urinary sodium and chloride usually gave evidence of two periodic components, one corresponding to activity and the other to the rhythm of either temperature or of urinary potassium.5. Urinary creatinine and phosphate usually followed the subject's routine of activity.6. Plasma samples were collected on a few occasions and analysed for phosphate and 11-hydroxycorticosteroids. Changes in plasma phosphate were usually, but not always, associated with similar changes in urinary phosphate, and changes in plasma corticosteroids were often, but not always, associated with similar changes in urinary potassium shortly afterwards.7. Observations are recorded on a subject alone in a cave for 127 days. His activity habits, though wildly variable, gave evidence of a period of 25.1 h and his urinary electrolyte excretion indicated a shorter period, of 24.6 h. During the following 3 days, when he remained in the cave but was visited frequently, his plasma corticosteroids and urinary potassium oscillated with a period of 16 h.8. The possible mechanisms controlling these rhythms are discussed.  (+info)

17-Hydroxycorticosteroids are a class of steroid hormones that are produced in the adrenal gland. They are formed from the metabolism of cortisol, which is a hormone that helps regulate metabolism, immune response, and stress response. 17-Hydroxycorticosteroids include compounds such as cortisone and corticosterone.

These hormones have various functions in the body, including:

* Regulation of carbohydrate, fat, and protein metabolism
* Suppression of the immune system
* Modulation of the stress response
* Influence on blood pressure and electrolyte balance

Abnormal levels of 17-hydroxycorticosteroids can indicate problems with the adrenal gland or pituitary gland, which regulates adrenal function. They are often measured in urine or blood tests to help diagnose conditions such as Cushing's syndrome (overproduction of cortisol) and Addison's disease (underproduction of cortisol).

11-Hydroxycorticosteroids are a class of steroid hormones that are produced in the adrenal gland. They are created when cortisol, a type of glucocorticoid hormone, is metabolized by the enzyme 11-beta-hydroxysteroid dehydrogenase type 2 (11-β-HSD2) in the kidneys. This results in the formation of cortisone, which is then converted back to cortisol as needed.

11-Hydroxycorticosteroids are important for regulating a variety of physiological processes, including metabolism, immune response, and stress response. They also have anti-inflammatory effects and are sometimes used in medical treatments to reduce inflammation and suppress the immune system.

Elevated levels of 11-hydroxycorticosteroids can indicate an overactive adrenal gland or a tumor that is producing excess cortisol. Low levels may be seen in conditions such as Addison's disease, which is characterized by underactivity of the adrenal gland.

Medical definitions of 11-hydroxycorticosteroids typically refer to the measurement of these hormones in urine or blood tests, which can help diagnose and monitor various medical conditions.

Hydroxycorticosteroids are a class of corticosteroid hormones that contain a hydroxyl group at the 11-beta position. They include naturally occurring hormones such as cortisol and artificially produced drugs used to treat various conditions like inflammation, autoimmune diseases, and allergies. These medications work by mimicking the effects of hormones produced in the adrenal gland, reducing inflammation and suppressing the immune system. Examples of hydroxycorticosteroids include cortisone, prednisone, and dexamethasone.

17-Ketosteroids are a group of steroid compounds that contain a ketone group at the 17th carbon position in their molecular structure. They are produced as metabolic byproducts of certain hormones, such as androgens and estrogens, in the human body.

The term "17-KS" or "17-ketosteroids" is often used to refer to a class of urinary steroid metabolites that can be measured in the urine to assess adrenal and gonadal function. The measurement of 17-KS is particularly useful in monitoring patients with certain endocrine disorders, such as congenital adrenal hyperplasia or adrenal tumors.

The two major 17-KS that are routinely measured in urine are androsterone and etiocholanolone, which are derived from the metabolism of testosterone and dehydroepiandrosterone (DHEA), respectively. Other 17-KS include tetrahydrocortisone, tetrahydrocortisol, and 5-androstene-3β,17β-diol.

It's worth noting that the measurement of 17-KS has largely been replaced by more specific tests, such as the measurement of individual steroid hormones or their metabolites using mass spectrometry-based methods.

Hydrocortisone is a synthetic glucocorticoid, which is a class of steroid hormones. It is identical to the naturally occurring cortisol, a hormone produced by the adrenal gland that helps regulate metabolism and helps your body respond to stress. Hydrocortisone has anti-inflammatory effects and is used to treat various inflammatory conditions such as allergies, skin disorders, and autoimmune diseases. It works by suppressing the immune system's response to reduce swelling, redness, itching, and other symptoms caused by inflammation.

Hydrocortisone is available in different forms, including oral tablets, topical creams, lotions, gels, and ointments, as well as injectable solutions. The specific use and dosage depend on the condition being treated and the individual patient's medical history and current health status.

As with any medication, hydrocortisone can have side effects, especially when used in high doses or for extended periods. Common side effects include increased appetite, weight gain, mood changes, insomnia, and skin thinning. Long-term use of hydrocortisone may also increase the risk of developing osteoporosis, diabetes, cataracts, and other health problems. Therefore, it is essential to follow your healthcare provider's instructions carefully when using this medication.

... (OHCSs) are corticosteroids that have an additional hydroxy (-OH) group. There are two main positions ... aldosterone corticosterone hydrocortisone 17-hydroxycorticosteroids (17-OHCSs) include: cortisone hydrocortisone MedlinePlus ... where the hydroxy group may be added: at carbon atom 11, and at carbon atom 17. 11-hydroxycorticosteroids (11-OHCSs) include: ...
17-hydroxycorticosteroids MeSH D06.472.040.585.478.195 - cortisone MeSH D06.472.040.585.478.225 - cortodoxone MeSH D06.472. ... hydroxycorticosteroids MeSH D06.472.040.585.353 - 11-hydroxycorticosteroids MeSH D06.472.040.585.353.118 - aldosterone MeSH ...
Hydroxycorticosteroids (OHCSs) are corticosteroids that have an additional hydroxy (-OH) group. There are two main positions ... aldosterone corticosterone hydrocortisone 17-hydroxycorticosteroids (17-OHCSs) include: cortisone hydrocortisone MedlinePlus ... where the hydroxy group may be added: at carbon atom 11, and at carbon atom 17. 11-hydroxycorticosteroids (11-OHCSs) include: ...
Chromophore switch from 11‐cis‐dehydroretinal (A2) to 11‐cis‐retinal (A1) decreases dark noise in salamander red rods. *Article ... 4. We conclude that M1 muscarinic receptor inhibition of IK(M) is transduced by G alpha q and/or G alpha 11, and that G alpha o ... 3. Immunoblots with specific anti-G-protein antibodies demonstrated the presence of both G alpha q and G alpha 11, while G ... Muscarinic M-current inhibition via G(αq/11) and α-adrenoceptor inhibition of Ca2+ current via G(αo) in rat sympathetic ...
Hydroxycorticosteroids [D06.472.040.585]. *11-Hydroxycorticosteroids [D06.472.040.585.353]. *Aldosterone [D06.472.040.585. ... Aldosterone, (11 beta,17 alpha)-Isomer*Aldosterone, (11 beta,17 alpha)-Isomer ...
Concentration of catecholamines, II-hydroxycorticosteroids, free and bound hydroxyproline in blood, free and total ... 11. [Autonomic regulation and emotional status in patients with ischemic heart disease having pain syndrome of various severity ... The content of 11-hydroxycorticosteroids, free and bound hydroxyproline in the peripheral blood, as well as the level of free ... Colágeno/metabolismo , Formação Reticular/fisiologia , 11-Hidroxicorticosteroides/sangue , Animais , Aorta/metabolismo , ...
These metabolites are readily determined by measuring urinary 17‑hydroxycorticosteroids (17-OHCS) or 17-ketogenic steroids (17- ... 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action 12.2 Pharmacodynamics 12.3 Pharmacokinetics 13 NONCLINICAL ... 11 DESCRIPTION Metopirone (metyrapone capsules) is an adrenal steroid synthesis inhibitor, available as 250‑mg capsules for ... Interpretation of 11‑desoxycortisol and ACTH Levels After Metopirone Administration Approximately 8 hours after administration ...
17-Hydroxycorticosteroids Preferred Concept UI. M0023177. Registry Number. 0. Scope Note. A group of hydroxycorticosteroids ... 17-Hydroxycorticosteroids Preferred Term Term UI T043950. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1965). ... Hydroxycorticosteroids [D06.472.040.585] * 11-Hydroxycorticosteroids [D06.472.040.585.353] * 17-Hydroxycorticosteroids [D06.472 ... A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as ...
September 4, 2013 11:34 AM Full Author List * Campisi J; Leem TH; Greenwood BN; Hansen MK; Moraska A; Higgins K; Smith TP; ...
VISIBLE BURROW SYSTEM AS A MODEL OF CHRONIC SOCIAL STRESS - BEHAVIORAL AND NEUROENDOCRINE CORRELATES Journal Article ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
17-Hydroxycorticosteroids 17-Hydroxyprogesterone use 17-alpha-Hydroxyprogesterone 17-Hydroxysteroid Dehydrogenases 17- ... 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ...
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... diurnal rhythm of plasma cortisol and ACTH with increased urinary excretion of free cortisol and 17-hydroxycorticosteroids (17- ... TSH-secreting pituitary macroadenoma in an 11-year-old girl. Acta Paediatr. 1992. 81:1058-1060. [QxMD MEDLINE Link]. ... Fewer than 20 cases of thyrotropinoma in children have been reported, all with onset after age 11 years. Pediatric ...
  • In 1968, Migeon et al described 6 patients with a syndrome of adrenal unresponsiveness to ACTH characterized by hypoglycemia, hyperpigmentation, feeding problems in infancy, low urinary 17-hydroxycorticosteroids, an ability to conserve sodium and increase aldosterone secretion in response to salt deprivation, and a lack of elevation of 17-hydroxycorticosteroid secretion or plasma cortisol concentration with ACTH administration. (medscape.com)
  • This test, usually given on an outpatient basis, determines plasma 11-desoxycortisol and/or ACTH levels after a single dose of Metopirone. (nih.gov)
  • Approximately 8 hours after administration of Metopirone, evaluate the values of ACTH and 11-desoxycortisol. (nih.gov)
  • Normal values will depend on the method used to determine ACTH and 11‑desoxycortisol levels. (nih.gov)
  • An intact HPA axis function is generally indicated by an increase in 11‑desoxycortisol to over 70 mcg/L. Because of an overlap between a normal ACTH response and an abnormal ACTH response, the ACTH response alone cannot be used to distinguish between healthy individuals and those with adrenal insufficiency. (nih.gov)
  • The second sister had low levels of plasma 11-hydroxycorticosterone that did not respond to adrenocorticotropic hormone (ACTH). (medscape.com)
  • Hydroxycorticosteroids (OHCSs) are corticosteroids that have an additional hydroxy (-OH) group. (wikipedia.org)
  • There are two main positions where the hydroxy group may be added: at carbon atom 11, and at carbon atom 17. (wikipedia.org)
  • A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. (nih.gov)
  • Kuingizwa kwa chalasana katika ugumu wa kila siku huruhusu tu kupunguza kiwango cha katekamini katika damu, lakini pia kuongeza yaliyomo kwenye cortisol katika plasma yake, na 17-ketosteroids na 17-hydroxycorticosteroids kwenye mkojo. (sportexistence.com)
  • Fewer than 20 cases of thyrotropinoma in children have been reported, all with onset after age 11 years. (medscape.com)
  • These metabolites are readily determined by measuring urinary 17-hydroxycorticosteroids (17-OHCS) or 17-ketogenic steroids (17-KGS). (nih.gov)
  • Urinary testosterone, 17-ketosteroids, 17-hydroxycorticosteroids, and serum androgen, follicle-stimulating hormones, and corticosteroid levels ramained within normal values with candicidin therapy. (bvsalud.org)
  • Hydroxycorticosteroids (OHCSs) are corticosteroids that have an additional hydroxy (-OH) group. (wikipedia.org)
  • A group of corticosteroids bearing a hydroxy group at the 11-position. (nih.gov)
  • 14. [The effect of orchidectomy on the excretion of testosterone, 17-ketosteroids, estrogens, pregnanediol, 17-hydroxycorticosteroids and gonadotropins in urine]. (nih.gov)
  • PMID- 5428635 TI - Circadian rhythms in plasma concentration of 11-hydroxycorticosteroids in men working on night shift and in permanent night workers. (nih.gov)
  • There were 9% more English strings and 11% more concepts than in the 2002 edition. (nih.gov)