A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and as a raw material for plasticizers. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Isomeric forms and derivatives of octanol (C8H17OH).
Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.
Isomeric forms and derivatives of hexanol (C6H11OH).
A colorless liquid with a fragrant odor. It is used as an intermediate, solvent and in cosmetics.
An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Agents that are capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of CONNEXINS, the family of proteins which form the junctions.
An oleanolic acid from GLYCYRRHIZA that has some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation.
A four carbon linear hydrocarbon that has a hydroxy group at position 1.
Isomeric forms and derivatives of pentanol (C5H11OH).
Miniaturized methods of liquid-liquid extraction.
An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
An acquired disorder characterized by recurrent symptoms, referable to multiple organ systems, occurring in response to demonstrable exposure to many chemically unrelated compounds at doses below those established in the general population to cause harmful effects. (Cullen MR. The worker with multiple chemical sensitivities: an overview. Occup Med 1987;2(4):655-61)

N-Substituted analogues of S-nitroso-N-acetyl-D,L-penicillamine: chemical stability and prolonged nitric oxide mediated vasodilatation in isolated rat femoral arteries. (1/84)

Previous studies show that linking acetylated glucosamine to S-nitroso-N-acetyl-D,L-penicillamine (SNAP) stabilizes the molecule and causes it to elicit unusually prolonged vasodilator effects in endothelium-denuded, isolated rat femoral arteries. Here we studied the propanoyl (SNPP; 3 carbon side-chain), valeryl (SNVP; 5C) and heptanoyl (SNHP; 7C) N-substituted analogues of SNAP (2C), to further investigate other molecular characteristics that might influence chemical stability and duration of vascular action of S-nitrosothiols. Spectrophotometric analysis revealed that SNVP was the most stable analogue in solution. Decomposition of all four compounds was accelerated by Cu(II) and cysteine, and neocuproine, a specific Cu(I) chelator, slowed decomposition of SNHP. Generation of NO from the compounds was confirmed by electrochemical detection at 37 degrees C. Bolus injections of SNAP (10 microl; 10(-8)-10(-3) M) into the perfusate of precontracted, isolated rat femoral arteries taken from adult male Wistar rats (400-500 g), caused concentration-dependent, transient vasodilatations irrespective of endothelial integrity. Equivalent vasodilatations induced by SNVP and SNHP were transient in endothelium-intact vessels but failed to recover to pre-injection pressures at moderate and high concentrations (10(-6)-10(-3) M) in those denuded of endothelium. This sustained effect (> 1 h) was most prevalent with SNHP and was largely reversed by the NO scavenger, haemoglobin. We suggest that increased lipophilicity of SNAP analogues with longer sidechains facilitates their retention by endothelium-denuded vessels; subsequent slow decomposition within the tissue generates sufficient NO to cause prolonged vasodilatation. This is a potentially useful characteristic for targeting NO delivery to areas of endothelial damage.  (+info)

A solvent model for simulations of peptides in bilayers. I. Membrane-promoting alpha-helix formation. (2/84)

We describe an efficient solvation model for proteins. In this model atomic solvation parameters imitating the hydrocarbon core of a membrane, water, and weak polar solvent (octanol) were developed. An optimal number of solvation parameters was chosen based on analysis of atomic hydrophobicities and fitting experimental free energies of gas-cyclohexane, gas-water, and octanol-water transfer for amino acids. The solvation energy term incorporated into the ECEPP/2 potential energy function was tested in Monte Carlo simulations of a number of small peptides with known energies of bilayer-water and octanol-water transfer. The calculated properties were shown to agree reasonably well with the experimental data. Furthermore, the solvation model was used to assess membrane-promoting alpha-helix formation. To accomplish this, all-atom models of 20-residue homopolypeptides-poly-Leu, poly-Val, poly-Ile, and poly-Gly in initial random coil conformation-were subjected to nonrestrained Monte Carlo conformational search in vacuo and with the solvation terms mimicking the water and hydrophobic parts of the bilayer. All the peptides demonstrated their largest helix-forming tendencies in a nonpolar environment, where the lowest-energy conformers of poly-Leu, Val, Ile revealed 100, 95, and 80% of alpha-helical content, respectively. Energetic and conformational properties of Gly in all environments were shown to be different from those observed for residues with hydrophobic side chains. Applications of the solvation model to simulations of peptides and proteins in the presence of membrane, along with limitations of the approach, are discussed.  (+info)

Agonist and potentiation actions of n-octanol on gamma-aminobutyric acid type A receptors. (3/84)

The n-octanol effects on the gamma-aminobutyric acid type A (GABAA) receptor were studied in human embryonic kidney 293 cells transfected with alpha1, beta2, and gamma2S subunit cDNAs. GABA-evoked currents had an EC50 of 13.3 +/- 1.7 microM and a Hill coefficient (nH) of 1.4 +/- 0.1. n-Octanol was also capable of evoking a small current with an EC50 of 1000 microM and an nH of 2. In addition, n-octanol modulated GABA-induced currents in a concentration-dependent manner. Coapplications of n-octanol increased peak currents evoked by 3 microM GABA with an EC50 of 190 microM and an nH of 1.8. The extent of potentiation decreased with increasing GABA concentrations and no potentiation was observed when n-octanol was coapplied with 1000 microM GABA. One-minute preapplication of 1000 microM n-octanol slightly potentiated 3 microM GABA-induced current, whereas it suppressed 300 microM GABA-induced current to 16% of the control, suggesting that 84% of the receptors underwent desensitization. Two models were used to explain n-octanol agonistic and potentiating actions on the alpha1beta2gamma2S GABAA receptor: n-octanol binds to multiple sites to exert multiple actions, or n-octanol acts as a partial agonist to manifest these actions. The partial agonist model is unique because it is a simpler model to explain n-octanol actions on the GABAA receptor.  (+info)

Functional gap junctions in the early sea urchin embryo are localized to the vegetal pole. (4/84)

Using the whole-cell voltage-clamp technique we have studied electrical coupling and dye coupling between pairs of blastomeres in 16- to 128-cell-stage sea urchin embryos. Electrical coupling was established between macromeres and micromeres at the 16-cell stage with a junctional conductance (G(j)) of 26 nS that decreased to 12 nS before the next cleavage division. G(j) between descendants of macromeres and micromeres was 12 nS falling to 8 nS in the latter half of the cell cycle. Intercellular current intensity was independent of transjunctional voltage, nondirectional, and sensitive to 1-octanol and therefore appears to be gated through gap junction channels. There was no significant coupling between other pairs of blastomeres. Lucifer yellow did not spread between these electrically coupled cell pairs and in fact significant dye coupling between nonsister cells was observed only at the 128-cell stage. Since 1-octanol inhibited electrical communication between blastomeres at the 16- to 64-cell stage and also induced defects in formation of the archenteron, it is possible that gap junctions play a role in embryonic induction.  (+info)

Quantitative trait loci influencing honeybee alarm pheromone levels. (5/84)

Quantitative trait loci (QTL) mapping procedures were used to identify loci that influence the levels of alarm pheromones found in the stinging apparatus of worker honeybees. An F1 queen was produced from a cross between a queen of European origin and a drone descended from an African subspecies. Haploid drones from the hybrid queen were individually backcrossed to European queens to produce 172 colonies. Samples of stings were taken from backcross workers of these colonies. Alarm pheromone levels were determined by gas chromatography. RAPD markers were scored from the haploid drone fathers of these colonies. The multiple-QTL model (MQM) of MapQTL was used to identify QTLs that influence the levels of four alarm pheromone components. Seven independent, potential QTLs were identified with LOD scores greater than two, and one at LOD 1.88. We identified one QTL for n-decyl acetate, three for n-octanol, four for isopentyl acetate, and one for hexyl acetate. One region of linkage group XI shows a strong influence on body size and the levels of three alarm pheromone components. This locus explained 40% of the variance for the amount of n-decyl acetate (LOD 6.57). In general, the QTLs influencing alarm pheromone levels were independent of previously identified loci that influenced the stinging behavior of these colonies. The only exception was a potential locus influencing levels of n-octanol, which was inversely correlated with stinging behavior.  (+info)

A cell type-specific and gap junction-independent mechanism for the herpes simplex virus-1 thymidine kinase gene/ganciclovir-mediated bystander effect. (6/84)

Tumor cells expressing the herpes simplex virus type 1 thymidine kinase (HSV-tk) gene are killed by nucleoside analogues such as ganciclovir (GCV). GCV affects not only the cells expressing HSV-tk but also neighboring cells that do not express the gene; this phenomenon commonly is called "bystander effect." GCV metabolites transfer via gap junctional intercellular communication (GJIC) accounts for the bystander effect in different cell lines, but other mechanisms have also been described. In this study, we analyzed the mechanisms of the bystander effect in two cell lines exhibiting different capacities of communication (DHD/K12 and 9L). The 9L cells exhibited a very good bystander effect, which was completely blocked by a long-term inhibitor of GJIC, 18 alpha-glycyrrhetinic acid. DHD/K12 cells exhibited a moderate bystander effect that was not abolished by 18 alpha-glycyrrhetinic acid or 1-octanol, another strong inhibitor of GJIC. Interestingly, we also observed a bystander effect in cultures where HSV-tk-expressing DHD/K12 cells were physically separated from their untransfected counterparts but grown in the same medium. Moreover, the transfer of filtered conditioned medium from GCV-treated HSV-tk-expressing DHD/K12 cells to DHD/K12 parental cells induced a decrease of survival in a concentration-dependent manner, suggesting that the bystander effect in this cell line was mediated by a soluble factor.  (+info)

Blocking and the detection of odor components in blends. (7/84)

Recent studies of olfactory blocking have revealed that binary odorant mixtures are not always processed as though they give rise to mixture-unique configural properties. When animals are conditioned to one odorant (A) and then conditioned to a mixture of that odorant with a second (X), the ability to learn or express the association of X with reinforcement appears to be reduced relative to animals that were not preconditioned to A. A recent model of odor-based response patterns in the insect antennal lobe predicts that the strength of the blocking effect will be related to the perceptual similarity between the two odorants, i.e. greater similarity should increase the blocking effect. Here, we test that model in the honeybee Apis mellifera by first establishing a generalization matrix for three odorants and then testing for blocking between all possible combinations of them. We confirm earlier findings demonstrating the occurrence of the blocking effect in olfactory learning of compound stimuli. We show that the occurrence and the strength of the blocking effect depend on the odorants used in the experiment. In addition, we find very good agreement between our results and the model, and less agreement between our results and an alternative model recently proposed to explain the effect.  (+info)

Effects of insulin-like growth factor-I on in vitro final oocyte maturation and ovarian steroidogenesis in striped bass, Morone saxatilis. (8/84)

Recombinant human (rh) insulin-like growth factor-I (IGF-I) was more potent than rhIGF-II at inducing in vitro germinal vesicle breakdown (GVBD), a marker for resumption of meiosis, in oocytes of striped bass. Treatment of ovarian fragments containing oocytes in intact follicles with rhIGF-I increased concentrations of estradiol-17beta and maturation-inducing steroid (MIS) 17,20beta, 21-trihydoxy-4-pregnen-3-one (20beta-S) in the culture medium and decreased testosterone levels. The follicles were too immature for oocytes to complete GVBD in response to 20beta-S (MIS incompetent) or hCG. Addition of 20beta-S to cultures did not increase the percentage of oocytes completing GVBD in response to rhIGF-I or rhIGF-II. Bovine insulin was without effect on GVBD or steroid production. Incubation of MIS-competent follicles with actinomycin D, cyanoketone, trilostane, 1-heptanol, or 1-octanol had no effect on rhIGF-I-induced GVBD, but attenuated hCG-induced GVBD and 20beta-S production. Cycloheximide inhibited rhIGF-I-induced GVBD. Collectively, these observations indicate that IGF-I can induce GVBD via MIS- and transcription-independent pathways without coupled gap junctions between oocytes and granulosa cells or among granulosa cells, but requires protein synthesis to do so. An rhIGF-I analogue that does not bind IGF-binding proteins, des(1,3)IGF-I, was more potent than rhIGF-I in inducing GVBD, suggesting ovarian IGF-binding proteins may inhibit IGF-I action.  (+info)

Objectives The occupational hazard of chemical absorption via dermal route was frequently assessed by evaluating the skin permeability (Kp) of chemical. In addition to in vitro testing using human skin, the quantitative structure-activity relationship (QSAR) has been employed as an alternative source to providing Kp. In the early Kp QSARs the octanol-water partition coefficient (log KOW) and molecular weight (MW) were commonly applied as dominant properties to describe transdermal transport of chemical. This study examined the efficacy of log KOW-/MW-based QSARs in Kp prediction.. ...
1. W.Y. Ko, L.J. Chen, S.T. Lin, and Y.P. Chen, Measurements for the Dissociation Conditions of Methane Hydrate in the Presence of 1,3,5-Trioxane and Oxolan-2-ylmethanol, J. Chem. Eng. Data, 56 (8): 3406-3410, 2011.. 2. Y.-C. Huang, J.-H. Hsu, Y.-C. Liao, W.-C. Yen, S.-S. Li, S.-T. Lin, C.-W. Chen, and W.-F. Su, Employing an amphiphilic interfacial modifier to enhance the performance of a poly(3-hexyl thiophene)/TiO2 hybrid solar cell, J. Mater. Chem., 21 4450- 4456, 2011.. 3. S.-N. Huang, T.A. Pascal, W.A. Goddard, P.K. Maiti, and S.-T. Lin, Absolute Entropy and Energy of Carbon Dioxide Using the Two-Phase Thermodynamic Model, J. Chem. Theory Comput., 7 (6): 1893-1901, 2011.. 4. M.T. Hsieh and S.T. Lin, A Predictive Model for the Excess Gibbs Free Energy of Fully Dissociated Electrolyte Solutions, AIChE J., 57 (4): 1061-1074, 2011.. 5. C.M. Hsieh, S. Wang, S.T. Lin, and S.I. Sandler, A Predictive Model for the Solubility and Octanol-Water Partition Coefficient of Pharmaceuticals, J. ...
Chiral 2-octanol is one of the key intermediates for preparation of liquid crystal materials, as well as many optically active pharmaceuticals. Lipase catalyzed kinetic resolution has proved to be an efficient technique for synthesis of enantiomerically enriched compounds. In the present study, optimization and kinetic modeling of kinetic resolution of (±)-2-octanol was done by using vinyl acetate as an acyl donor in n-heptane as a solvent. Response surface methodology (RSM) and four-factor-five-level Centre Composite Rotatable Design (CCRD) were employed to evaluate the effect of various parameters such as speed of agitation, enzyme loading, temperature and acyl donor/alcohol molar ratio on conversion, enantiomeric excess (ee), enantioselectivity and initial rate of reaction. Acylation of 2-octanol with vinyl acetate catalyzed by Novozyme 435 follows the ternary complex mechanism (ordered bi-bi mechanism) with inhibition by 2-octanol.
Chiral 2-octanol is one of the key intermediates for preparation of liquid crystal materials, as well as many optically active pharmaceuticals. Lipase catalyzed kinetic resolution has proved to be an efficient technique for synthesis of enantiomerically enriched compounds. In the present study, optimization and kinetic modeling of kinetic resolution of (±)-2-octanol was done by using vinyl acetate as an acyl donor in n-heptane as a solvent. Response surface methodology (RSM) and four-factor-five-level Centre Composite Rotatable Design (CCRD) were employed to evaluate the effect of various parameters such as speed of agitation, enzyme loading, temperature and acyl donor/alcohol molar ratio on conversion, enantiomeric excess (ee), enantioselectivity and initial rate of reaction. Acylation of 2-octanol with vinyl acetate catalyzed by Novozyme 435 follows the ternary complex mechanism (ordered bi-bi mechanism) with inhibition by 2-octanol.
TY - CHAP. T1 - The effect of hydrostatic pressure & octanol on the conductance change produced by a quantum of acetylcholine at the frog neuromuscular junction. AU - Ashford, Michael L J. AU - MacDonald, A. G.. AU - Wann, K. T.. PY - 1982. Y1 - 1982. M3 - Chapter (peer-reviewed). BT - Eighth Annual Congress of European Undersea Biomedical Society. PB - North Sea Medical Center. ER - ...
VCPL, Hyderabad India offers Octan-1-ol HPLC CAS # 111-87-5. We are best Octanol, Octan-1-ol HPLC, Octyl alcohol, 1-Octanol, Octan-1-ol HPLC manufacturer
An experiment was undertaken by Tanniet al. (1992) to determine the octanol-water partition coefficient of 2-(2-methylpropoxy)ethanol and thirteen other ethylene glycol ethers as part of a study evaluating structure-toxicity relationships. The estimation (solubility ratio) methodology followed was according to that outlined by Tanni and Hashimoto (1982) and involved analyses by gas-liquid chromatography with flame ionisation detection and a glass column. Under the conditions of the experiment, 2-(2-methylpropoxy)ethanol was reported to be evidently separated from the organic (n-octanol) phase that had been dissolved in water. Following analyses, a log Kow of 0.75 was determined for 2-(2-methylpropoxy)ethanol. ...
Transport of metals between aqueous phase and soil/sediment/suspended matter should be described on the basis of measured soil/water, sediment/water and suspended matter/water equilibrium partition coefficients (Kp), instead of using common mathematical relationships based on, for example, octanol-water partition coefficients, as is usually done for organic chemicals (TGD, 1996). Kpsoil Four reliable studies were identified in the EU RAR for diantimony trioxide which report soil Kp. Vangheluwe et al. (2001) report the results of a transformation experiment in soil using Sb2O3and SbCl3. The transformation experiment was performed for a duration of 24 weeks, with soils incubated at 20ºC, with a final humidity of 22g/100g dry substance (both soils). The incubation was initiated with 2 drying/rewetting cycles. Calculation of the Kpsoil, using a control soil in Vangheluwe et al. (2001), results in a partition coefficient in sandy soils of 81 l/kg (log Kpsoil= 1.91) and 150 l/kg (log Kpsoil= 2.18) in ...
This study evaluates the potential application of micellar liquid chromatography (MLC) to predict skin permeation with a series of model compounds. MLC has previously been found to be useful in the prediction of partition coefficient values (logP) for pharmaceutical compounds, yet has not been incorporated in skin permeability models prior to this work. This article provides statistically supported data that this technique enhances the ability to predict the permeability of similar drugs through the skin (Kp). The replacement of a traditional physicochemical parameter, namely the octanol-water partition coefficient (logPow) with a chromatographically determined value (logPmw), results in a quantitative partition-permeability relationship that is robust to variation. MLC offers many benefits compared with the traditional techniques employed to obtain logP values.. ...
Waiver. In accordance with column 2 of REACH Annexes XIII, the adsorption / desorption study (required in section 9.3.1 and 9.3.3) do not need to be conducted if, based on the physicochemical properties the substance can be expected to have a low potential for adsorption (e.g. the substance has a low octanol-water partition coefficient). The partition coefficient of HQEE was determined in a reliable study (Young 2012) where the measured log Kow is 0.41. Therefore, HQEE is considered to have low potential for absorption and no further testing is required. ...
No data on toxicokinetics, metabolism and distribution are available for 2-aminoethyldiethylamine. Based on the available toxicological studies and the physico-chemical properties, particularly water solubility and octanol-water partition coefficient, absorption via oral, inhalative and dermal route a respective assessment is possible. The test substance is expected to be well absorbed by the respiratory and gastro-intestinal tracts and through the skin.The target test substance is assumed to be widely distributed and comprehensively metabolized. If not excreted unchanged, excretion of the metabolites may occur predominantly via the urine. The test substance is not expected to accumulate and there is no evidence for a (sex-)specific toxic effect ...
For each SSRI, laboratory environmental fate measurements will include the following: aqueous solubility; octanol-water partition coefficient (Kow); acid dissociation constant (pKa); soil adsorption coefficient (Koc); hydrolysis and aqueous direct photolysis rates at pH 5,7and 9; indirect photolysis rates including the hydroxyl radical rate constant; irradiated and dark aerobic-aquatic metabolism; and ready biodegradability. Major degradation products will be identified wherever possible. The occurrence of each SSRI and major metabolites/degradation products will be measured over one year in raw and treated wastewater, and receiving water at sub-ppb levels. Potential loads to waste treatment facilities will be assessed through surveys of numbers of prescriptions filled by local pharmacies. Acute toxicity and chronic exposure tests for survival and reproduction will be conducted with Ceriodaphnia following EPA protocols on each SSRI as well as on raw sewage water and treated effluent. Toxicity ...
A mathematical model has been developed that is based on the molecular mechanism of diffusion and that explicitly incorporates the non-uniform structure of the stratum corneum. The model is used to predict permeability coefficients of chemicals based on their molecular weight (MW) and octanol-water partition coefficient (P).
A poster (P165) presented at ASMS 2017, Indianapolis, discusses three sample preparation methodologies for 52 drug analytes, and presents evaluations of recovery, matrix effects and process efficiency. While dilute and shoot methods are easy and affordable, they can result in shortened LC column lifetimes and increased MS instrumentation downtime. Matrix effects can also effect sensitivity and overall method performance. Supported Liquid extraction (SLE) and Solid Phase Extraction (SPE) provide cleaner samples for LC-MS/MS and more robust clinical assays.. Successful sample preparation method development requires understanding the retention mechanism of the analytes in the assay. The octanol-water partition coefficient (logP) and acid dissociation constant (pKa) of the compounds of interest are important properties that can guide sample preparation strategy and optimization of method conditions.. Conclusions. ...
Crystals of an ion-channel-forming peptaibol peptide in a partial membrane environment have been obtained by cocrystallizing antiamoebin with n-octanol. The antiamoebin molecule has a bent helical conformation very similar to that established for Leu-zervamicin, despite a significantly different sequence for residues 1-8. The bent helices assemble to form a polar channel in the shape of an hour glass that is quite comparable to that of Leu-zervamicin. The molecules of cocrystallized octanol are found in two different areas with respect to the assembly of peptide molecules. One octanol molecule mimics a membrane segment along the hydrophobic exterior of the channel assembly. The other octanol molecules fill the channel in such a way that their OH termini satisfy the C==O moieties directed into the interior of the channel. Structure parameters for C82 H27 N17 O20(.3) C8H18O are space group P2(1) 2(1) 2(1), a = 9.143(2) A, b = 28.590(8) A, c = 44.289(8) A, Z = 4, agreement factor R1 = 11.95% for 4,113
BioAssay record AID 24206 submitted by ChEMBL: Partition coefficient between octanol and pH 7.2 phosphate buffer; NT means Not tested.
The researchers say if this were to be scaled up for industrial systems the engineered bacteria would produce the non-toxic derivative of 1-octanol, which would then be recovered and chemically transformed back into 1-octanol, ready for use.. The team found that their system produced 1-octanol without affecting the growth of the bacteria. They also found the system produced more 1-octanol than a system without the derivatization step, which they think is related to the fact that the derivative is not only less toxic but also more soluble in the surrounding water or solvent.. Dr. Jones said: A more soluble chemical may move away from the cells quicker, where its less likely to interfere with any of the bacterias processes.. Now the team has shown the concept of creating derivatives using programmed microorganisms, they want to set up a complete system, from production of the derivative to recovery of the desired chemical.. This will help them refine the process, and potentially scale it up ...
Lonsdale, T. H.; Lauterbach, L.; Malca, S. H.; Nestl, B. M.; Hauer, B.; Lenz, O. H2-driven biotransformation of n-octane to 1-octanol by a recombinant Pseudomonas putida strain co-synthesizing an O2-tolerant hydrogenase and a P450 monooxygenase. Chem. Commun. 2015, 51 (90), 16173-16175.. Farmer, T. J.; Clark, J. H.; Gothe, M. L.; Macquarrie, D. J.; Sherwood, J. p-Cymenesulphonyl Chloride: A Bio-Based Activating Group and Protecting Group for Greener Organic Synthesis. J. Braz. Chem. Soc. 2015, 26 (9), 1914-1919.. ...
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Sigma-Aldrich offers Aldrich-218405, 3-Octanol for your research needs. Find product specific information including CAS, MSDS, protocols and references.
Ternary liquid-liquid phase equilibria (LLE) of water and acetone with 1-octanol, 2-octanol, 1-pentanol and isopentanol (3-methyl-1-butanol) at 298, 303 and 308 K are presented. With the exception of water + acetone + 1-octanol at 303 K, these systems have not been previously investigated at these temperatures. The data are successfully correlated using the NRTL model. The UNIFAC predictive model was also tested with the various group parameter databases ...
Let us now consider the transfer of amino acids from water to a bilayer membrane. According to the calculations of MacCallum et al. (2007), transfer from bulk water to the membrane interior correlates well with the water/cyclohexane scale. In contrast, the transfer of free energy from bulk water to the membrane interface correlates very well with the water/octanol scale. This is the result one would expect a priori. Indeed, it was noted previously that the partitioning of short peptide, designed to occupy the membrane-solution interface, correlates well with the water/octanol scale (Wimley and White, 1996; Wimley et al., 1996). In summary, the water/octanol thermodynamic scale does not reflect the partitioning of amino acids in the interior of membranes but to the membrane-solution interface. Finally, let us consider an even more complex situation, the insertion of transmembrane helices using the translocon expression system. The fascinating measurements of Hessa et al. (2005a) are suggestive of ...
This should be self-explanatory, but just in case its not: your t-score goes in the T Score box, you stick your degrees of freedom in the DF box (N - 1 for single sample and dependent pairs, (N 1 - 1) + (N 2 - 1) for independent samples), select your significance level and whether youre testing a one or two-tailed hypothesis (if youre not sure, go with the ...
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The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Positioning the Juvenile in the Postoperative Span Way of thinking the child on the from side with the chairman of the bed flat or at the level prescribed by the neurosurgeon. After in unison district is examined, the progeny may feel more congenial replacing that thing of clothing previously removing another one (Bunik et al. Do your investigate ahead language on [url=http://spacelink.org/learning/education-28/lecture-3/index.html]order maxalt 10mg amex[/url] pain treatment center brentwood ca. In a few words, the core of interest is added to a ark containing even volumes of o and a nonmiscible systematic liquid such as n-octanol or a biotic lipid or vegetable oil. Turn over submit hygiene includes both agency washing with soap and bath-water and the consume of alcohol-based products (gels, rinses, foams) that do not ask for water. Afterwards 2 weeks of not respiration [url=http://spacelink.org/learning/education-28/lecture-11/index.html]buy discount claritin 10mg on line[/url] allergy ...
Eseja: Investigation into the Use of Short-Column Reversed-Phase LC in the Determination of log P Values 2.. Aim To illustrate how gas chromatography (GC) may b
The aromatization of 2-octanol derived from castor oil as a byproduct in the formation of sebacic acid was investigated on various zeolite catalysts. Zn ion-exchanged MFI (ZSM-5) zeolites with small silica/alumina ratios and zinc contents of 0.5 to 2.0 wt. % were determined to exhibit good and stable activity for the reaction at 623 to 823 K. The yield of aromatics was 62% at 773 K and the space velocity 350 to 1400 h−1. The temperature and contact time dependences of the product distributions indicated the reaction pathways of 2-octanol→dehydration to 2-octene→decomposition to C5 and C3 compounds→further decomposition to small alkanes and alkenes→aromatization with dehydrogenation. Alcohols with carbon numbers of 5 to 8 exhibited similar distributions of products compared to 2-octanol, while corresponding carbonyl compounds demonstrated different reactivity.
Autori: L. Copolovici and U. Niinemets. Editorial: Chemosphere, 61, p.1390-1400, 2005.. Rezumat:. Cuvinte cheie: Monoterpenes; Henrys law constant; Octanol/water partition coefficient; Partition coefficients; Temperature dependence. ...
Pseudomonas putida Idaho utilizes toluene, m-xylene, p-xylene, 1,2,4-trimethylbenzene, and 3-ethyltoluene as growth substrates when these hydrocarbons are provided in a two-phase system at 5 to 50% (vol/vol). Growth also occurs on Luria-Bertani medium in the presence of a wide range of organic solvents. The ability of the organism to grow in the presence of organic solvents is correlated with the logarithm of the octanol-water partition coefficient, with dimethyl-phthalate (log P(OCT) = 2.3) being the most polar solvent tolerated. During growth with p-xylene (20% [vol/vol]), there was an initial lag period accompanied by cell death, which was followed by a period of exponential growth. The stationary phase of growth was characterized by a dramatic decrease in cell viability, although cell dry weight and turbidity measurements slowly increased. Electron micrographs revealed that during growth in the presence of p-xylene, the outer cell membrane becomes convoluted and membrane fragments are shed ...
The White Bass (Morone chrysops) is also called the sand bass, white bass, and silver bass. It is a freshwater fish of the family Moronidae that is primarily found in the Midwest United States. They spot a deep and compressed lateral body with silver-white to pale green color. White Basss have a total length between 10
Daphnia magna 48-hr LC50, fish (fathead minnow) 96-hr LC50, estrogen receptor binding affinity (RBA), skin irritation potential ...
Daphnia magna 48-hr LC50, fish (fathead minnow) 96-hr LC50, estrogen receptor binding affinity (RBA), skin irritation potential ...
Fished Lake Lavon this past weekend. Saturday at Brockdale; Sunday at Highland. This is the follow-up video showing the action Sunday. Windy and lots of waves to deal with, luckily the twelve foot jon boat and 2.5 Suzuki Outboard made for an easy run to the Water Treatment Plant for some fun with White Bass…. [read more]. ...
The experimental Rm values for a series of aminoalkanethiosulfuric acids, mercaptoalkanamines and aminoalkyl disulfides were determined by reverse phase thin layer chromatography. The Rm values were determined for various concentrations of methanol: water and the correlation obtained was extrapolated to 100% water. These values permitted the calculation of the log P values for each substance. The log P values obtained by this method were compared with those obtained using the shake-flask method and by theoretical calculations utilizing fragment constants.
Part A Simulation Oxford Statistics - Monte Carlo simulations were performed for I-, Br-and Cl-, in water using ab initio pair potential. solvent influences the outcome of a chemical reaction
i) LIPOPHILICITY (e.g., LogD and cLogP). Historically, lipophilicity was the first of the structural properties to be recognized as important for CNS penetration. As early as 1897, Overton observed correlations between oil-water partition coefficients and narcotic potencies of a series of compounds in tadpoles [4]. By the 1960s, Hansch introduced the octanol/water system, which became the standard for measuring partition coefficients, and he demonstrated that blood-brain barrier permeation is optimal when the LogP values are in the range of 1.5-2.7, with the mean value of 2.1. In line with Hanschs findings, the mean value for cLogP for 74 marketed CNS drugs has been reported by Leeson to be 2.5. A number of different guidelines for predicting BBB permeation based on structural properties have been proposed, which suggests preferred ranges for LogP of between 1 and 5 (Table 1). In addition to permeability, lipophilicity plays an important role in other pharmacokinetic properties that may affect ...
Partition coefficients - logP, and its pH-dependent pair, logD - are crucial in estimating the distribution of drugs in the human body. Drugs with higher partition coefficients modelled in an octanol/water system are more likely to be distributed in the hydrophobic tissues like blood. However, molecules with low partition coefficients can mostly be found in lipophilic areas of the human body, like lipid bilayers of cells. The quality of the logP/logD prediction can be enhanced by incorporating measured logP/logD data through training ...
Molecular weight:203.3; Physical form:Colourless or yellow liquid, with an aromatic odour. Density:0.956 (20 °C); Composition:Tech. material is 95% pure. Flash point:124 °C; Vapour pressure:9 Pa (30 °C); 4.7 Pa (25 °C); Henry constant: 20 Pa m3 mol-1 (20 °C, calc.); Partition coefficient(n-octanol and water):logP = 3.83; Solubility:In water 60 mg/l (20 °C). Miscible with most organic solvents, e.g. acetone, benzene, toluene, xylene, methanol, isopropanol, kerosene.; Stability:Stable up to 200 °C. In water, DT50 (40 °C) 11 d (pH 4 and pH 10), 12 d (pH 7 ...
explain the change in surface tension of mixture of water+alcohol(n-octanol,n-heptanol,n-butanol)? discuss their degree of their solubility in water and this affect to surface tension ...
The influence of the initial adsorption coverage at the surface of an air bubble (radius 0.74 mm) formed at a capillary orifice on profiles of its rising velocities and shape variations was investigated in n-octanol, n-octyltrimethylammonium bromide (CTAB) and Tween80 solutions of different concentrations. The bubb
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Modern biofuels offer the potential to decrease engine out emissions while at the same time contributing to a reduction of greenhouse gases produced from individual mobility. In order to deeply investigate and improve the complete path from biofuel production to combustion, in 2007 the cluster of excellence Tailor-Made Fuels from Biomass was installed at RWTH Aachen University. Since then, a whole variety of possible fuel candidates have been identified and investigated. In particular oxygenated fuels (e.g. alcohols, furans) have proven to be beneficial regarding the particulate matter (PM)/ NOx trade-off [1, 2, 3] in diesel-type combustion. Alcohols that provide a longer ignition delay than diesel might behave even better with regard to this trade-off due to higher homogenization of the mixture. Recent studies carried out within the Cluster of Excellence have discovered new pathways to derive 1-octanol from biomass [4], which features a derived cetane number (DCN) of 39 ...
Définitions de 1 2 nitrophenoxy octane, synonymes, antonymes, dérivés de 1 2 nitrophenoxy octane, dictionnaire analogique de 1 2 nitrophenoxy octane (anglais)
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Wondering what peoples opinions are with the turbo engine as far as octane choice as it pertains to altitude (and outside temp) to some degree. Im taking...
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News Analysis Love in the Scientific Literature There are countless ways for scientists to say, I love you. Naming a slime-mold beetle after your wife (and another after your ex-wife) is, apparently, one of them. ...
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PLOS ONE 6(8): 1-11. Spromberg JA, and Scholz NL. 2011. Estimating the future decline of wild Coho salmon populations resulting ... Integrated Environmental Assessment and Management 9999: 1-9. Chow, M. I., Lundin, J. I., Mitchell, C. J., Davis, J. W., Young ... American Fisheries Society Symposium 64: 1-21. Scholz NL, Myers MS, McCarthy SG, Labenia JS, McIntyre JK, Ylitalo GM, Rhodes LD ... PLOS ONE 6(12): 1-12. NOAA Coastal Storm Programs. Available online at: Stormwater and Salmon- Pre-spawn Mortality of Coho ...
ISBN 1-56032-091-5. Escher BI, Hermens JL (October 2002). "Modes of action in ecotoxicology: their role in body burdens, ... 7 (1): 28-49. doi:10.1002/ieam.100. PMID 21184568. McKim JM, Schmieder PK, Carlson RW, Hunt EP (1987). "Use of respiratory- ... tricaine methanesulfonate and 1-octanol". Environmental Toxicology and Chemistry. 6 (4): 295-312. doi:10.1002/etc.5620060407. ... cardiovascular responses of rainbow trout (Salmo gairdneri) in identifying acute toxicity syndromes in fish: Part 1. ...
12 (1): 1208. doi:10.1186/1472-6882-12-70. PMC 3541197. PMID 22643043. William A Correll, Jr. (5 February 2019). "(Example, one ... Flowers have 4 sepals and 4 petals, yellow to greenish yellow in color sometimes tipped with red, about 1 to 3.5 millimetres ( ... in China the main components are geraniol and 1-octanol; and in India the main component is phenethyl alcohol. Cinnamyl alcohol ...
... is the ester of 1-octanol and gallic acid. As a food additive, it is used under the E number E311 as an ...
The solubility of 1-octanol in water is 2.3 grams per liter. It was first prepared in 1908 by Bouveault-Blanc reduction of a ... "MSDS for 1,4-Cyclohexanedimethanol". Sigma-Aldrich. Reddy, LV; KY Sudheer; OV Reddy (June 2010). "Analysis of volatile aroma ... Like other 8-carbon alcohols, such as 1-octanol, this compound is only slightly soluble in water but highly soluble in many ... 1%) in the production of cyclohexanedimethanol, a commodity chemical, during hydrogenation of dimethyl terephthalate. C6H4( ...
... and 2-Octanol Catalyzed by KOH". Industrial & Engineering Chemistry Research. 35 (11): 3848-3853. doi:10.1021/ie960200c. Cox, ... 214 (1-2): 1-38. doi:10.1016/j.tox.2005.06.001. ISSN 0300-483X. PMID 16011869. Stickney, Julie A; Sager, Shawn L; Clarkson, ... 9 (1): 69-75. doi:10.1007/s11743-006-0377-8. S2CID 94398901. Guckert, J.B.; Walker, D.D.; Belanger, S.E (1996). "Environmental ... In the usual application, alcohols and phenols are converted into R(OC2H4)nOH where n ranges from 1 to 10. Such compounds are ...
It is usually produced by hydroformylation of heptene and the dehydrogenation of 1-octanol. Octanal can also be referred to as ...
... in a biphasic system of n-octanol (hereafter simply "octanol") and water: log ⁡ P oct/wat = log 10 ⁡ ( [ solute ] octanol un- ... For instance, for an octanol-water partition, it is log ⁡ P oct/wat I = log 10 ⁡ ( [ solute ] octanol I [ solute ] water I ... The partition coefficient between n-Octanol and water is known as the n-octanol-water partition coefficient , or Kow. It is ... octanol}}^{\text{ionized}}+{\big [}{\text{solute}}{\big ]}_{\text{octanol}}^{\text{un-ionized}}}{{\big [}{\text{solute}}{\big ...
Pharmacokinetic research on 1-octanol lead to the discovery that 1-octanol metabolized into caprylic acid in the body and that ... 135 (Pt 1): 105-16. doi:10.1093/brain/awr301. PMID 22120148. Vilariño-Güell C, Soto-Ortolaza AI, Rajput A, Mash DC, ... 241 (1): 54-61. doi:10.1007/bf00870673. PMID 8138823. S2CID 9502687. Louis ED, Barnes L, Albert SM, Cote L, Schneier FR, ... While its long-term effects are not yet established, the improvement in tremor score from baseline was durable at 1 year and 2 ...
ISBN 978-1-4200-9084-0. Acetic acid, octyl ester in Linstrom, Peter J.; Mallard, William G. (eds.); NIST Chemistry WebBook, ... It is classified as an ester that is formed from 1-octanol (octyl alcohol) and acetic acid. It is found in oranges, grapefruits ... 37 (1): 80-95. doi:10.1021/je00005a024. "Octyl acetate". chemdats.blogspot.com. 2014-11-04. Archived from the original on 2014- ... Octyl acetate can be synthesized by the Fischer esterification of 1-octanol and acetic acid: CH3(CH2)7OH + CH3CO2H → CH3(CH2) ...
In addition to 1,3-butadiene also substituted dienes such as isoprene or cyclic dienes such as cyclopentadiene can be used. A ... Subsequent cracking of 1-methoxyoctane gives 1-octene and methanol for recycle. While the reaction is catalyzed by Pd(0) ... ISBN 978-1-891389-53-5. A. Behr: Angewandte homogene Katalyse (as Google-Book) in German (CS1 maint: multiple names: authors ... Upon displacement by new 1,3-butadiene the product telomer is liberated while the catalyst is regenerated and can continue the ...
Jan/Feb 2008: 1 - via Bio-Intergal Resource Center (BIRC). "A Review of "Organic" and Other Alternative Methods for Fire Ant ... Limonene and its oxidation products are skin irritants, and limonene-1,2-oxide (formed by aerial oxidation) is a known skin ... Long chain aliphatic hydrocarbon alcohols and aldehydes like 1-octanol and octanal are second important group of substances. ...
M. Kaisheva, R. De Levie, Kinetic observations of the capacitance of near-saturated 1-octanol solutions, J. Electroanal. Chem ... V. Ilieva, B. Damaskin, M. Kaisheva, Study of Differential Capacity and Adsorption Parameters of 1-Propanol, Bulgarian Chemical ... Milliana Kroumova Kaisheva (Bulgarian: Миляна Крумова Кайшева) (1 November 1945 in Sofia, Bulgaria - 24 March 2003 in Sofia, ... A Comparison Based on Nonlinear Regression Analysis, Langmuir, 1 (1985) 760. M. Kaisheva, Correlation Between Adsorption ...
622 (1-2): 85-95. doi:10.1016/S0166-1280(02)00620-6. McKim JM, Schmieder PK, Carlson RW, Hunt EP (April 1987). "Use of ... ISBN 1-56032-091-5. Kaiser KLE (March 2003). "The use of neural networks in QSARs for acute aquatic toxicological endpoints". ... 27 (1): 77-90. doi:10.1002/qsar.200710099. Schultz TW (1989). "Nonpolar Narcosis: A review of the mechanism of action for ... 10 (1): 115-131. doi:10.1002/etc.5620100113. Veith GD, Broderius SJ (July 1990). "Rules for distinguishing toxicants that cause ...
For example, from 1-decene, hydroformylation gives the C11 alcohol: C8H17CH=CH2 + H2 + CO → C8H17CH2CH2CHO C8H17CH2CH2CHO + H2 ... Tests of repeated bolus dosages of 1-hexanol and 1-octanol showed potential for CNS depression and induced respiratory distress ... 1⁄2 Al2O3 Alternatively ethylene can be oligomerized to give mixtures of alkenes, which are subjected to hydroformylation, this ...
A set of solvation parameters derived for protein interior from protein engineering data was also different from octanol scale ... Newer parameters have thus been derived from octanol-water partition coefficients or other similar data. Such parameters ... it was close to cyclohexane scale for nonpolar atoms but intermediate between cyclohexane and octanol scales for polar atoms. ... The model has the following functional form: G s = − 1 8 π ϵ 0 ( 11 ϵ ) ∑ i , j N q i q j f G B {\displaystyle G_{s}=-{\frac ...
The pheromone contains more than 40 different compounds, including pentylacetate, butyl acetate, 1-hexanol, n-butanol, 1- ... octanol, hexylacetate, octylacetate, and 2-nonanol. These components have a low molar mass and evaporate quickly. This ...
Agonists include: 1-Octanol 1-Nonanol 1-Decanol 1-Heptanol Coumarin Olfactory receptor GRCh38: Ensembl release 89: ...
Sangster, J. (1997-05-28). Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry. John Wiley & Sons. ISBN ... 1-Octanol, with eight carbons, is practically insoluble in water, and its immiscibility leads it to be used as a standard for ... For example, among the alcohols, ethanol has two carbon atoms and is miscible with water, whereas 1-butanol with four carbons ...
... and 1-octanol (long-chain alcohol, non-ionic).[citation needed] Many biological compounds are amphiphilic: phospholipids, ...
It has a constant octanol-water partition coefficient of log P = 1.23 in the pH range between 1 and 7. It is classified as a ... 434 (1-2): 21-28. doi:10.1016/S0014-2999(01)01502-3. PMID 11755161. Dündar Y, Dodd S, Strobl J, Boland A, Dickson R, Walley T ( ... 434 (1-2): 21-28. doi:10.1016/S0014-2999(01)01502-3. PMID 11755161. Patat A, Paty I, Hindmarch I (July 2001). "Pharmacodynamic ... 317 (1): 369-77. doi:10.1124/jpet.105.096701. PMID 16399882. S2CID 46510829. "Zaleplon". pubchem.ncbi.nlm.nih.gov. U.S. ...
30 (1): 69-80. doi:10.1093/chemse/bji002. PMID 15647465. Matarazzo V, Clot-Faybesse O, Marcet B, Guiraudie-Capraz G, Atanasova ... "Entrez Gene: OR1G1 olfactory receptor, family 1, subfamily G, member 1". Sanz G, Thomas-Danguin T, Hamdani EH, Le Poupon C, ... Examples of agonists include: nonanal (strong) 1-nonanol (strong) 2-ethyl-1-hexanol (strong) γ-decalactone (strong) ethyl ... hexanal 1-hexanol cyclohexanone The pattern of 6-carbon antagonists compared to ~9-carbon agonists is likely explained by OR1G1 ...
The molecular formula C8H18O may refer to: Di-tert-butyl ether Dibutyl ether 2-Ethylhexanol Octanols 1-Octanol 2-Octanol 3- ... Octanol 4-Octanol 3,5-dimethylhexan-3-ol 2,3,4-trimetilpentan-2-ol This set index page lists chemical structure articles ...
1-4, pp. 377-396, doi:10.1016/S0022-1139(00)85282-3{{citation}}: CS1 maint: multiple names: authors list (link) US 5118804, J. ... 8. Synthese von 1-Thio-glycosiden", Liebigs Ann. Chem. (in German), vol. 1983, no. 7, pp. 1249-1256, doi:10.1002/jlac. ... H.A. van Doren, R. van der Geest (1989), "Synthesis and liquid crystalline properties of the n-alkyl-1-thio-α-D- ... n-octyl-β-d-1-thioglucopyranoside is a colorless, odorless, hygroscopic, crystalline solid which readily dissolves in water and ...
A small amount of the diene 1,7-octadiene is required as a proton acceptor. The reaction mechanism for this reaction is a four- ... 1: 32. doi:10.1016/j.chempr.2016.05.002. Toyomi Matsu-ura; Satoshi Sakaguchi; Yasushi Obora; Yasutaka Ishii (2006). "Guerbet ... Oxo alcohols - a different reaction which gives similar products Guerbet alcohols 2-Ethyl-1-butanol 2-Ethylhexanol 2- ... Propylheptan-1-ol 2-Butyl-1-octanol 2-Butyl-1-octanol Noweck, Klaus; Grafahrend, Wolfgang (2006). "Fatty Alcohols". Ullmann's ...
Amberlite LA-2 in 1-octanol diluent maintains nearly full capacity up to a pH value of 6.0 and is readily regenerated by ... ISBN 0-309-05123-1. Rea, C. L., & LaPerriere, J. D. (1985). Effects of Calcium Magnesium Acetate, a Road Deicer, on the Lentic ...
A solution of 13.0 g (0.1 mol) of 1-octanol in 25 mL of dichloromethane was added dropwise to a solution of 16.1 g (0.1 mol) of ... This process has been observed in the fluorination of pivalaldehyde, which affords a mixture of 1,2-difluoro-1,2- ... Perfluorinated alkylamines, such as Ishikawa's reagent (N,N-diethyl-1,1,2,3,3,3-hexafluoropropylamine WRONG MOLECULE IN SCHEME ... of 1-fluorooctane as a colorless liquid, bp 42-43° (20 mm). 19F NMR (CCl3F): -218.8 ppm (tt, 2J = 49 Hz, 3J = 25 Hz). Hudlicky ...
... octanol and water) is the same as the ratio between the concentrations of the target chemical in each media at equilibrium. ... Kow is the octanol-water partition coefficient for the target chemical (dimensionless ratio); Ps is the vapor pressure of the ... The following list gives the fugacity capacities for common medias: Air (under ideal gas assumptions): Zair = 1/RT Water: ... 1/Psv Where: R is the Ideal gas constant (8.314 Pa·m3/mol·K); T is the absolute temperature (K); H is the Henry's law constant ...
372 (1): 66-73. doi:10.1007/s00216-001-1195-5. PMID 11939214. S2CID 29195651. In early 1971, when IMS was referred to as plasma ... Siuzdak, Gary (1 April 2004). "An Introduction to Mass Spectrometry Ionization: An Excerpt from The Expanding Role of Mass ... In the positive mode, when the discharge current of corona discharge is 1-5 μA on the nebulized solvent, N2 gas molecules are ... 10 (1): 53-77. Bibcode:1991MSRv...10...53B. doi:10.1002/mas.1280100104. ISSN 0277-7037. Thomson, BA (2007). Gross, Michael; ...
The octanol-water partition coefficient, usually expressed as its logarithm (Log P), is a measure of differential solubility of ... followed by a revised formula which takes a different assumption of complete miscibility in octanol. log 10 ⁡ ( S ) = 0.8 − log ... 321 (1-2): 1-11. doi:10.1016/j.ijpharm.2006.07.011. PMID 16920290. C. Houk; R. Post, eds. (1997). Chemistry, Concept and ... One can calculate the amount of AgCl that will dissolve in 1 liter of pure water as follows: Ksp = [Ag+] × [Cl−] / M2 ( ...
The rates of block and unblock of AMPA receptor currents were 1.5 × 105 M−1 s−1 and 0.58 s−1, respectively. Perampanel did not ... Perampanel's chemical formula is 2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile; it has a bipyridine ... 1 s at 3 μM), concentration-dependent inhibition of AMPA receptor currents. ... InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22) 16-26(23(21)27)19-9-2-1-3-10-19/h1-14,16H N ...
SPMD samplers are most effective at absorbing hydrophobic pollutants with an octanol-water partition coefficient (Kow) ranging ... Open Analytical Chemistry Journal 2:1-9. Harman C, Allan IJ, Vermeirssen ELM. 2012. Calibration and Use of the Polar Organic ... commonly 1 μL). Any compound with a log Kow of less than or equal to 3 can concentrate in a POCIS sampler. Applicable classes ... Table 1). Currently, there are two POCIS configurations that are targeted for different classes of contaminants. A general ...
... of the distribution coefficient of the nonionized form between octanol and water) of −1.43. These chemical parameters indicate ... 293 (1): H457-66. doi:10.1152/ajpheart.00002.2007. PMID 17369473. Ma T, Tian X, Zhang B, Li M, Wang Y, Yang C, et al. (March ... 20 (1): 1-12. doi:10.1111/obr.12753. PMID 30230172. Rydén L, Grant PJ, Anker SD, Berne C, Cosentino F, Danchin N, et al. (May ... 32 (1): 61-72. doi:10.1038/sj.ijo.0803695. PMID 17653063. Mead E, Atkinson G, Richter B, Metzendorf MI, Baur L, Finer N, et al ...
In enzymology, an octanol dehydrogenase (EC 1.1.1.73) is an enzyme that catalyzes the chemical reaction 1-octanol + NAD+ ⇌ {\ ... The systematic name of this enzyme class is octanol:NAD+ oxidoreductase. This enzyme is also called 1-octanol dehydrogenase. ... Portal: Biology v t e (CS1 French-language sources (fr), EC 1.1.1, NADH-dependent enzymes, Enzymes of unknown structure, All ... displaystyle \rightleftharpoons } 1-octanal + NADH + H+ Thus, the two substrates of this enzyme are 1-octanol and NAD+, whereas ...
The n-octanol-water partition coefficient, Kow is a partition coefficient for the two-phase system consisting of n-octanol and ... The value is greater than one if a substance is more soluble in fat-like solvents such as n-octanol, and less than one if it is ... Corwin Hansch later proposed the use of n-octanol as an inexpensive synthetic alcohol that could be obtained in a pure form as ... A variant of the UNIFAC system can also be used to estimate octanol-water partition coefficients. Definition of the Kow or P- ...
The octanol-water partition coefficient (Kow) of chloropicrin is estimated to be 269. Its soil adsorption coefficient (Koc; ... p. 1. Archived from the original (PDF) on 6 October 2013. Retrieved 20 September 2013. "NIOSH Pocket Guide to Chemical Hazards ... It is commonly used as a stand-alone treatment or in combination / co-formulation with methyl bromide and 1,3-dichloropropene. ... Retrieved 1 Apr 2019. "Control Measures for Chloropicrin" (PDF). California Department of Pesticide Regulation. January 6, 2015 ...
Cheng T (Nov 2007). "Computation of octanol-water partition coefficients by guiding an additive model with knowledge". Journal ... 11 (1): 56. doi:10.1186/s13321-019-0375-2. PMC 6688265. PMID 31399858. "PubChem Source Information". The PubChem Project. USA: ... from over 1 million assay experiments performed on more than 2 million small-molecules covering almost 10,000 unique protein ...
Octanol/Water Partition Coefficients, and Isobaric Azeotropic Vapor-Liquid Equilibrium". Journal of Chemical & Engineering Data ... This gives: ln ⁡ γ 2 = ( ln ⁡ γ 2 ∞ + 2 ( ln ⁡ γ 1 ∞ − ln ⁡ γ 2 ∞ ) Φ 2 ) Φ 1 2 {\displaystyle \ln \gamma _{2}=\left(\ln \gamma ... contribution method for predicting MOSCED parameters with application to limiting activity coefficients in water and octanol/ ... λ 1 − λ 2 ) 2 + q 1 2 q 2 2 ( τ 1 T − τ 2 T ) 2 ψ 1 + ( α 1 T − α 2 T ) ( β 1 T − β 2 T ) ξ 1 ] + d 12 {\displaystyle \ln \ ...
Breakdown of castor oil in strong base gives 2-octanol, both a fragrance component and a specialized solvent, and the ... 112 (1): 10-30. doi:10.1002/ejlt.200900138. "The Castor Bean: A Plant Named After A Tick". Wayne's Word: An Online Textbook of ... 76 (1): 49-55. doi:10.1590/S0001-37652004000100005. PMID 15048194. Bryan, Cyril P. (1930). The Papyrus Ebers, Translated from ... July 1, 1940, p. 18. Cecil Adams (1994-04-22). "Did Mussolini use castor oil as an instrument of torture?". The Straight Dope. ...
The experimental octanol/water partition coefficient (logP) of estradiol enanthate is 6.7. Estradiol enantate was first ... 898-. ISBN 978-1-4757-2085-3. Recio R, Garza-Flores J, Schiavon R, Reyes A, Diaz-Sanchez V, Valles V, Luz de la Cruz D, Oropeza ... 42 (1): 13-28. doi:10.1016/0010-7824(90)90088-D. PMID 2117515. Oliva Filho, W. M., & Santos, N. da C. (1992). Efeitos na ... doi:10.1007/978-1-59259-246-3_13. ISBN 978-1-61737-129-5. Robert B. Greenblatt; William E. Barfield; Edwin C. Jungck (January ...
This quantitative descriptor for microenvironment was derived from the octanol-water partition coefficient, (known as Rekker's ... One for the transfer of unfolded chains into octanol, which is relevant to the hydrocarbon core of a bilayer. The Stephen H. ... from water to POPC interface and to n-octanol. These two scales are then used together to make Whole residue hydropathy plots. ... 1-butanol and pyridine were used as the mobile phase in this particular scale and glycine was used as the reference value. ...
In addition, the greater the lipophilicity of the steroid, as measured by the octanol/water partition coefficient (logP), the ... 30 (1): 48-55. doi:10.1080/17843286.1975.11716973. PMID 1231448. v t e (CS1 maint: multiple names: authors list, Prodrugs, ... 1-26. doi:10.1007/978-1-4614-1004-1_1. ISBN 978-1-4614-1003-4. Polderman J (February 1962). "Suspensions in pharmaceutical ... 30 (1): 48-55. doi:10.1080/17843286.1975.11716973. PMID 1231448. Valentino Stella; Ronald Borchardt; Michael Hageman; Reza ...
... is a highly lipophilic molecule having an octanol-water partition coefficient (pH 7.4) of 3.0, while the log P of ... 418 (1): 161-6. doi:10.1016/j.bbrc.2011.12.153. PMID 22244872. Fu L, Wang S, Wang X, Wang P, Zheng Y, Yao D, et al. (December ... 6 (1): 3. doi:10.1038/s41598-016-0007-2. PMC 5431371. PMID 28442756. Jang SW, Liu X, Chan CB, Weinshenker D, Hall RA, Xiao G, ... 52 (1): 38-43. doi:10.1055/s-0044-102009. PMID 29466824. Campleman SL, Brent J, Pizon AF, Shulman J, Wax P, Manini AF (December ...
Most Cyphomyrmex species are found to contain 3-octanol. This is thought to act as an alarm signal across species. Traces of ... 32 (1): 8-15. doi:10.1111/j.1365-3032.2006.00534.x. ISSN 1365-3032. S2CID 10651662. Schultz, Ted R.; Brady, Seán G. (2008-04-08 ... 93 (1): 17-21. Bibcode:2006NW.....93...17F. doi:10.1007/s00114-005-0048-z. ISSN 1432-1904. PMID 16315027. S2CID 13437020. ... 15 (1): 17-25. doi:10.1007/BF02767322. ISSN 1439-5444. S2CID 20230853. Lacua, Lucimiere; Villemant, Claire; Bueno, Odaire; ...
The log octanol-water partition coefficient (log P) is -1.20E+00; its water solubility is 7.46E+05 mg/L at 25 °C. Vapor ... 20 (1): 45-6. doi:10.1007/BF01789112. PMID 7202882. Chou CH, Cheng CL, Huang CC (May 2004). "A validated HPLC method with ... 1 (12): 975-8. doi:10.1093/carcin/1.12.975. PMID 11272113. Anisimov VN, Ostroumova MN, Dil'man VM (1980). "Inhibition of the ... Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin ...
... the KOC can be determined based on the octanol-water partition coefficient (KOW). COC is the organic carbon normalized sediment ... Using 1/1000 to convert COC in kilograms OC to grams OC and substituting a known water effects concentrations (e.g. FCV), the ... Sediment Quality Values Refinement: 1988 Update and Evaluation of Puget Sound AET Vol 1. PTI Environmental Services, Bellevue, ... ESB (micrograms per gram OC) is calculated as: ESB = KOCFCV(1/1000) The calculated ESB is site-specific. The equation for the ...
... octanol, and methyl isobutyl ketone. This simple procedure allows the removal of most metal-containing impurities (e.g. iron, ... Tantalum is estimated to make up about 1 ppm or 2 ppm of the Earth's crust by weight. There are many species of tantalum ... 460 (1-2): 222-226. Bibcode:2004TSF...460..222T. doi:10.1016/j.tsf.2004.01.073. Soisson, Donald J.; McLafferty, J. J.; Pierret ... 26 (1-10): 823. doi:10.1016/S0734-743X(01)00135-X. S2CID 92307431. Russell, Alan M.; Lee, Kok Loong (2005). Structure-property ...
Using the octanol-water partition coefficient and a 100-year precipitation event for the area, a worst-case estimate of 75 mg/L ... 1] Archived June 4, 2009, at the Wayback Machine "The Technological Steps of Hydrogen Introduction" (PDF). Storhy.net. p. 24. ... November 1, 2007 - A propane pipeline exploded near Carmichael, Mississippi, about 30 miles (48 km) south of Meridian, ... On 26 September 2022, a series of explosions and subsequent major gas leaks occurred on the Nord Stream 1 and Nord Stream 2 ...
Octanol and water are immiscible. The distribution of a compound between water and octanol is used to calculate the partition ... Esters of octanol, such as octyl acetate, occur as components of essential oils. It is used to evaluate the lipophilicity of ... 2-Octanol Record in the GESTIS Substance Database of the Institute for Occupational Safety and Health Bhattacharjee, A.; Roy, M ... Octanol is mainly produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the ...
Hi! Can I get a quote for a GreenScreen Assessment of 1-Octanol, 2-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)-, (2S)- [1180131-16-1]? ... Is anyone else interested in sharing the cost of a GreenScreen assessment of 1-Octanol, 2-(1,1,2,2,3,3,4,4,4-nonafluorobutyl ... GreenScreen® assessments published after 1/1/19 expire at 5-year intervals, except for assessments of Benchmark 1 chemicals, ... ALSO CALLED (S)-2-(perfluorobutyl)octan-1-ol View all synonyms (1) ...
... , Z. Bayat* and M. Zanoozi ... Biological activit ies contain the octanol/water partition coefficient (lo g P). The final regression equation included four ... DFT-Based QSAR Prediction of 1-Octanol/Water Partition Coefficient of Adamantine derivatives drugs. ...
3-Octanol. 2-Octanone; methyl hexyl ketone. 3-Octanone; ethyl amyl ketone. ... beta]-Bourbonene; 1,2,3,3a,3b[beta],4,5,6,6a[beta],6b[alpha]-deca-hydro-l[alpha]-isopropyl-3aa-methyl-6-methylene-cyclobuta [1, ... 1-(p- Methoxyphenyl)-1-penten-3-one; [alpha]-methylanisylidene acetone; ethone. 1-(p- Methoxyphenyl)-2-propanone; anisylmethyl ... 1 As determined by using the method (or, in other than alcoholic beverages, a suitable adaptation thereof) in section 9.129 of ...
Octanol and 1,1‐Dioctyl Ether from Biomass‐Derived Platform Chemicals. Julis, Jennifer; Leitner, Walter (Corresponding author) ... Octanol and 1,1‐Dioctyl Ether from Biomass‐Derived Platform Chemicals ... Octanol and 1,1‐Dioctyl Ether from Biomass‐Derived Platform Chemicals ... Octanol and 1,1‐Dioctyl Ether from Biomass‐Derived Platform Chemicals ...
EPA 600-1-79-043. repository copy. AWBERC Library/Cincinnati,OH. 10/17/2014. ... Part 1. Pentachlorophenol, 2,4-Dinitrophenol, Tricaine. Methanesulfonate and 1-Octanol.. ...
1-octanol dehydration on Al2O3-SiO2 catalyst. en_US. dc.title.alternative. Al2O3-SiO2 katalizör üzerinde 1-oktanol dehidrasyonu ... In this study, the effect of heterogeneous acid catalysts was investigated to product distribution by 1-octanol dehydration. ... Bu çalışmada, heterojen asit katalizörün 1-oktanol dehidrasyonunda, ürün dağılımına etkisi araştırılmıştır. Kullanılan ... 1-octanol). For the usage of whole catalysts, the dehydration reaction proceeded on 150 ̊C and the reaction time was 4 h. The ...
2-ETHYLHEXAN-1-OL LR (FOR SYNTHESIS) (2-ethylhexanol, ios-octanol). د.إ200.00 ... 2-ETHYLHEXAN-1-OL LR (FOR SYNTHESIS) (2-ethylhexanol, ios-octanol) quantity. ... Plot 518, Area No 1, Sector No 5,. New Industrial Area. Umm Al Quwain. United Arab Emirates ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
1 INDICATIONS AND USAGE 2 DOSAGE AND ADMINISTRATION 2.1 Dosage in Adults 2.2 Dosing in Patients with Hepatic Impairment 2.3 ... Table 1. Incidence (% of subjects) of Treatment-Emergent Adverse Events MedDRA Preferred Term Placebo (n = 1456) Ramelteon 8 mg ... At Week 1, patients who received 8 mg of ramelteon had a mean VAS score (46 mm on a 100 mm scale) indicating more fatigue in ... In this study, when the PSG results from nights 1 and 2 of Month 7 were compared to the results from nights 22 and 23 of Month ...
Girard, B.; Durance, T., Headspace volatiles of sockeye and pink salmon as affected by retort process, Food Chem. Toxicol., 2000, 65, 1, 34-39. 90 matching species were found. For each matching species the following will be displayed: ...
1-Octanol] .We manufacture and distribute chemical reagents for research use only or various antibodies. ... N-1-Naphthylethylenediamine Dihydrochloride Guaranteed Reagent. 1,10-Phenanthroline Hydrochloride Monohydrate Guaranteed ...
2-Octanol. sec-Caprylic alcohol. 8. 18. 1. 130.22. -31.6. 179. 0.819. ... 1-Pentanol. Amyl alcohol. 5. 12. 1. 88.15. -78. 138. 0.814. 1-alkanol. 1-Hexanol. Caproyl alcohol. 6. 14. 1. 102.17. -46. 157. ... 1-Octanol. Capryl alcohol. 8. 18. 1. 130.22. -15. 195. 0.829. 1-alkanol. 1-Nonanol. Nonyl alcohol. 9. 20. 1. 144.25. -5. 214. ... 1-Tridecanol. 13. 28. 1. 200.35. 31. 287. 0.82231. 1-alkanol. 1-Tetradecanol. Tetra decylalcohol. 14. 30. 1. 214.38. 38. 296. ...
Termed as octanol-assisted liposome assembly (OLA), it essentially works as a bubble-blowing process at a micro scale and uses ... The new method has been dubbed octanol-assisted liposome assembly, or OLA. As Dekker explains: "OLA offers a flexible platform ... The scientists publish their findings in the online edition of Nature Communications on Friday 22 January (Octanol-assisted ... 1-octanol The new bubbling-blowing method uses a type of alcohol as a solvent. One of the problems with the earlier ...
Cox, J.D.; Pilcher, G., Thermochemistry of Organic and Organometallic Compounds, Academic Press, New York, 1970, 1-636. ... Benzene, 1-methyl-2,4-dinitro- (C7H6N2O4) ... Benzene, 1,4-diiodo- (C6H4I2). *Di-tert-butyl sulfide (C8H18S) ... Benzene, 2-methyl-1,3-dinitro- (C7H6N2O4) ... Ethylene, 1,2-dichloro-, (Z)- (C2H2Cl2). *(E)-Stilbene (C14H12) ...
1 INDICATIONS AND USAGE 1.1 Homozygous Familial Hypercholesterolemia 2 DOSAGE AND ADMINISTRATION 2.1 Initiation and Maintenance ... Table 1: Recommended Regimen for Titrating Dosage DOSAGE. DURATION OF ADMINISTRATION BEFORE CONSIDERING INCREASE TO NEXT DOSAGE ... 1. Liver problems. JUXTAPID can cause liver problems such as increased liver enzymes or increased fat in the liver. *Your ... The mean percent change in LDL-C from baseline through Week 26 is shown in Figure 1 for the 23 patients who completed the ...
1-octanol and 1-hexanol were efficient cosolvents consistent with the datasets observed for commercial APGs. Salt addition ... 5-(3-Bromo-4-hydroxy-5-methoxyphenyl)-7,7-dimethyl-7H-indolo[1,2-a]quinolinium perchlorate (Ia) was used as an indicator for ... 5-(3-Bromo-4-hydroxy-5-methoxyphenyl)-7,7-dimethyl-7H-indolo[1,2-a]quinolinium Perchlorate as a New Indicator for Anionic ...
Bi/Carbon for the oxidation of 2-octanol was investigated in a 500ml stirred tank reactor. The fast reaction rate drops ... The maximum conversion reached was 15% with calcined copper oxide catalyst for 1-octanol oxidation. ... The low activity of 5 wt.%Pt-1 wt. % ...
117 Partition Coefficient (n-octanol/water), HPLC Method. Chemistry, Toxicology, Environment. OECD Test No. 118 Determination ... 107 Partition Coefficient (n-octanol/water): Shake Flask Method. Chemistry, Toxicology, Environment. ... 1 OECD Principles on Good Laboratory Practice. Residues (Part 5A), also Guideline for data to support efficacy of disinfectants ... EPPO PP 1/116(3) Weeds in forests. Guidelines for efficacy evaluation of herbicides: weeds in Australian forests. ...
Octanol avoidance assays.. Octanol avoidance assays were performed as described in Chao et al. (2004) and as modified by Harris ... 1).. JZL184 or 2-AG still inhibited aversive responses in ckr-2-, dop-1-, npr-3-, octr-1-, ser-2-, and ser-4-null animals. In ... D, OCTR-1 dose-response curve for 2-AG. E, 2-AG inhibition of aversive responses to 1-octanol in ser-4-null animals. F, SER-4 ... The EC50s for 2-AG and AEA are in the range of EC50s reported for human CB1, 125 nm (Luk et al., 2004) and 89 nm (McAllister et ...
n-hexanol 10.3%; n-heptanol 5.3%; n-octanol 9.5%; n-nonanol 4.1%; n-decanol* 3.5%; n-octadecanol* 7.6%. It was reported that ... n-hexanol 10.3%; n-heptanol 5.3%; n-octanol 9.5%; n-nonanol 4.1%; n-decanol* 3.5%; n-octadecanol* 7.6%. It was reported that ... citrate (TEC). The percutaneous absorption rate of undiluted n-octanol was 50%, this was increased in squalene but decreased in ... citrate (TEC). The percutaneous absorption rate of undiluted n-octanol was 50%, this was increased in squalene but decreased in ...
Octanol/water partition coefficient as log Pow: 3.37 Auto-ignition temperature: 640°C Viscosity: 0.73 mPa*s at 70°C ... Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01. Flash point: 66°C c.c.. Explosive limits, vol% in air: 1.7- ...
The mechanism of the present coprecipitation of aromatic hydrocarbons with CyD was discussed based on the data of 1 : 1 ... Publications] I.SANEMASA: The Solubility of(Biphenyl,Naphtalene)-(Benzene,Cyclohexane,1-Octanol)Binary Mixtures in Water ... 1-Octanol) Binary Mixtures in Water. Bull. Chem Soc. Jpn.62(4). 1061-1064 (1989). *. Description. 「研究成果報告書概要(欧文)」より ...
1,2-Distearoyl-Rac-Glycero-3-Phosphocholine 816-94-4 Distearoyl phosphatidylcholine;1,2-Distearoyl-sn-glycero-3-phosphocholine ... 818-61-1 2-Hydroxyethyl acrylate;Ethylene glycol monoacrylate C5H8O3 ... 1-Bromo-2-butanone;2-Oxobutyl bromide; Bromomethyl ethyl ketone C4H7BrO ... 1,3-Dibromoacetone;1,3-Dibromo-2-propanone C3H4Br2O ... 4-Methyl-1-Heptanol C8H18O 817-95-8 Ethyl ethoxyacetate;Ethyl 2 ...
  • 1-Octanol is manufactured for the synthesis of esters for use in perfumes and flavorings. (wikipedia.org)
  • The continuous biocatalytic synthesis of ( R )-2-octanol carried out in an enzyme membrane reactor showed an excellent process stability of the biocatalysts, resulting in a turnover number of 15 million for the applied alcohol dehydrogenase. (rsc.org)
  • Its synthesis is carried out by a free-radical addition of 1-octanol to acrylic acid. (scentree.co)
  • The synthesis scheme for the colloids' synthesis is given in Figure 1. (harvard.edu)
  • Ethanol;Alcohol;Distilled spirits;Ethanol, undenatured;Ethyl alcohol, undenatured;1-Hydroxyethane;Absolute ethanol;Aethanol;Aethylalkohol;Alcohol (ethyl alcohol);Alcoho. (chinachemnet.com)
  • NOR-PC-SNEDDS was prepared using NOR-PC, Ethyl oleate, Labrasol, Cremophor EL and transcutol HP at a weight ratio of 1:2:3.36:2.24:2.4 (w/w/w/w/w). (dovepress.com)
  • The T. confusum larvae specifically emitted the volatiles 1-octen-3-one, benzeneacetaldehyde and decanal, whilst the adults specifically emitted the volatiles 2-methyl and 2- ethyl-1,3-benzenediols, the known semiochemicals 1-pentadecene, 2-methyl and 2-ethyl-1,4- benzoquinones and a series of yet to be fully identified unsaturated hydrocarbons. (openagrar.de)
  • The S. granarius adults specifically emitted the volatiles 2-methylpropanoic acid and 3-methylbutanoic acid, whilst infested wheat grain produced the following volatile organic compounds, 2-methylfuran, 2- ethylfuran, 2-methyl-1-butanol, 2-ethyl-2-pentenal and 2,5-dimethylpyrazine. (openagrar.de)
  • 2-Ethyl-1-butanol (IUPAC name: 2-ethylbutan-1-ol) is an organic chemical compound. (chemchart.com)
  • Get chemical information updates for 2-Ethyl-1-butanol sent to your email. (chemchart.com)
  • C 12 H 14 O 3 CAS No: 77-83-8 206.24 g/mol 30ml (1 fl oz) Ethyl methylphenylglycidate, commonly known as "strawberry aldehyde", is an organic compound used in the flavor industry in artificial fruit flavors, in particular strawberry. (consolidated-chemical.com)
  • Other constituents found in amounts between 5-10% are (E)-2-octenal, (E,E) 2,4-decadienal, 2-nonenal and 5 ethyl cyclopentene-1-carbaldehyde. (reishiandrosesbotanicals.com)
  • Physical properties of binary and ternary mixtures of ethyl acetate, ethanol, and 1-octyl-3-methyl-imidazolium bis(trifluoromethylsulfonyl)imide at 298.15 K // J. Chem. (finechem-mirea.ru)
  • for the other alcohols including decan-1-ol, at least 65% of the absorbed dose was excreted as CO₂ in the expired air. (europa.eu)
  • The percutaneous absorption rate of undiluted n-octanol was 50%, this was increased in squalene but decreased in castor oil or TEC This was also reported with the other alcohols tested and the tendency was more pronounced at higher concentrations. (europa.eu)
  • 1,2 Medium chain alcohols, such as butanol or pentanol, are commonly used co-surfactants. (chromatographyonline.com)
  • Based on the reliable inhalation study and feeding study described above together with the weight of evidence from other alcohols across the category, it is concluded that octan-1-ol is unlikely to cause developmental effects. (europa.eu)
  • Three different alcohols were investigated: 1-adamantanemethanol (A), 1H,1H,2H,2H-perfluoro-1-octanol (F) and isopropanol (I). Samplings of polycaprolactone (PCL) at various reaction times showed a linear increase in the polymer molecular weight with time, with very narrow polydispersity, confirming the living nature of the catalytic system. (lboro.ac.uk)
  • Alcohols can be converted into halo alkenes by reacting it with any one of the following reagent 1. (brainkart.com)
  • Azelastine hydrochloride is sparingly soluble in water, methanol and propylene glycol, and slightly soluble in ethanol , octanol, and glycerine. (rxlist.com)
  • 11. Iglesias M., Orge B., Tojo J. Densities and refractive indices for acetone+methanol+1-propanol at 298.15 K // J. Chem. (finechem-mirea.ru)
  • 1-Octanol, also known as octan-1-ol, is the organic compound with the molecular formula CH3(CH2)7OH. (wikipedia.org)
  • 50% of undiluted octan-1-ol was absorbed, compared with approximately 15% of a 5% solution. (europa.eu)
  • Based on this it is concluded that octan-1-ol is not expected to impair fertility. (europa.eu)
  • A reliable study using octan-1-ol (Hellwig, 1997) and performed to OECD guidelines, reported a LOAEL of 130 mg/kg bw/day (the lowest dose tested) for maternal toxicity and an NOAEL of 1300 mg/kg bw/day for teratogenicity and foetotoxicity (the highest dose tested). (europa.eu)
  • Based upon the above information, octan-1-ol is not required to be classified in accordance with EU guidelines. (europa.eu)
  • The main applications include ligand-based in silico (virtual) drug screening, ADME-Tox (adsorption, distribution, metabolism, excretion, and toxicity) property prediction, physical molecular property prediction (1-octanol-water partition coefficient, solubility), and measurement of the diversity of chemical compounds in a library. (hindawi.com)
  • Polarity and water vs. octanol solubility The thyroxine molecule is considered polar because it contains 4 polar functional groups, mixed into a total of 15 carbon atoms. (essaywriter4me.com)
  • [1] Hence these coefficients are a measure of differential solubility of the compound between these two solvents. (chemeurope.com)
  • The ideal solubility of the substances in 1-octanol, calculated from thermophysical parameters was found to correlate with the reported experimental data. (figshare.com)
  • The aim of this study, understanding the acidic-basic properties of the Al2O3-SiO2 catalysts and its impact on the dehydration of primary alcohol (1-octanol). (iyte.edu.tr)
  • It is also called 1-octanol, capryl alcohol and caprylic alcohol, and comes in both liquid and solid forms. (acme-hardesty.com)
  • CH 3 (CH 2 ) 9 OH CAS No: 112-30-1 158.28 g/mol 1-Decanol is a straight chain fatty alcohol with ten carbon atoms. (consolidated-chemical.com)
  • 1-Methylcyclohexanol is a tertiary alcohol. (theinsaneasylumblog.com)
  • Dicaprylyl carbonate is a diester (double ester) of carbonic acid and caprylyl alcohol (1-Octanol containing eight carbon atoms) and is the powerful performer in fast-spreading emollients. (beautyambassade.com)
  • 2-Octanol is a fatty alcohol. (laballey.com)
  • It is an octanol and a secondary alcohol. (laballey.com)
  • Octanol , also known as mushroom alcohol, is a chemical that attracts biting insects, like mosquitos. (reishiandrosesbotanicals.com)
  • Oxycodone hydrochloride dissolves in water (1 g in 6 to 7 mL) and is considered slightly soluble in alcohol (octanol-water partition coefficient is 0.7). (globalmedpharma.com)
  • 1.5E6 OH/cm3) Half-Life = 6.851 Hrs Ozone Reaction: No Ozone Reaction Estimation Fraction sorbed to airborne particulates (phi): 0.00771 (Junge,Mackay) Note: the sorbed fraction may be resistant to atmospheric oxidation Soil Adsorption Coefficient (PCKOCWIN v1.66): Koc : 1 Log Koc: 0.000 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]: Rate constants can NOT be estimated for this structure! (chemspider.com)
  • Chemicals having log octanol/water partition coefficients between 1 and 2 are well absorbed. (cdc.gov)
  • The assessment of bioaccumulation based on the 1-octanol/water partition coefficients of 2.47 [Meylan & Howard, 1995]. (europa.eu)
  • These compounds were chosen to span a wide range of structural classes and physical properties (e. g. octanol-water partition coefficients) and susceptibility to bio¬transformation based on reliable aqueous BCF data that are available in the literature for either trout or carp (or both species). (cefic-lri.org)
  • The thyroxine molecule is soluble in the nonpolar solvent 1-octanol. (essaywriter4me.com)
  • Highly lipid soluble: octanol/water partition coefficient 67, 84-91% protein bound. (derangedphysiology.com)
  • They also found the system produced more 1-octanol than a system without the derivatization step, which they think is related to the fact that the derivative is not only less toxic but also more soluble in the surrounding water or solvent. (sciencebulletin.org)
  • 2-Octanol is a colorless liquid that is poorly soluble in water but soluble in most organic solvents. (laballey.com)
  • The large molecule here can form 'decent' dispersion force attractions to the solvent octanol molecules(which are a mainly nonpolar carbon chain), using its two aromatic rings and their attached iodine atoms. (essaywriter4me.com)
  • These errors are primarily due to getting sufficiently converged energies to give accurate differences of large numbers, particularly for the large-molecule solvent octanol. (openrepository.com)
  • NOR-PC was prepared by solvent evaporation method with a mixture of phospholipid and NOR at a mass ratio of 3:1. (dovepress.com)
  • Figure 2 shows water encapsulated within a spherical interface formed by PS-PS+PEI particles in a water and 1-octanol mixture. (harvard.edu)
  • A mixture of isomeric chiral 2:2 helical complexes was formed with Cu(I), with a slight preference (1.4:1) for a single directional isomer. (northumbria.ac.uk)
  • Three phosphonium ionic liquids (ILs), two imidazolium ILs and one benchmark organic mixture (40 wt% tri-n-octylamine in 1-octanol: TOA/1-octanol) were applied as solvents. (utwente.nl)
  • Excess molar isentropic compressibilities, excess molar volumes, and excess sound speeds of the 1-propanol+diethyl ether+1-octanol ternary mixture and constituent binary mixtures at 298.15 K // Int. J. Thermophysics. (finechem-mirea.ru)
  • Esters of octanol, such as octyl acetate, occur as components of essential oils. (wikipedia.org)
  • 10. K. Pirgelovfi 1, S. Balfi~ 1, T. W. Schultz 2 Model-Based QSAR for Ionizable Compounds: Toxicity of Phenols Against Tetrahymenapyriformis Arch. (ajrconline.org)
  • A response-plane has been developed with Tetrahymena pyriformis population growth impairment toxicity data [log 1/50% growth inhibitory concentration (IGC50)], the 1-octanol/water partition coefficient (log Kow), and the energy of the lowest unoccupied molecular orbital (Elumo). (qsardb.org)
  • In a reliable study (Nelson et al, 1990), the NOAEC for maternal toxicity, foetotoxicity and teratogenicity in rats following inhalation exposure to 1-octanol during gestation days 1-19 was 0.4 mg/l (the highest attainable concentration). (europa.eu)
  • Energy-entropy prediction of octanol-water logP of SAMPL7 N-acyl sulfonamide bioisosters. (openrepository.com)
  • 5. Gardas R.L., Oswal S. Volumetric and transport properties of ternary mixtures containing 1-propanol, triethylamine or tri-n-butylamine and cyclohexane at 303.15 K: Experimental data, correlation and prediction by ERAS model // Thermochimica Acta. (finechem-mirea.ru)
  • Octanol is mainly produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the alkylaluminium products. (wikipedia.org)
  • It was revealed that symmetric, asymmetric and complex esters of succinic acid, complex ester of adipic acid (based on octanol-1, ethylene glycol and caproic acid) and dibenzyl ester of sebacic acid have relatively good electrical conductivity. (neftemir.ru)
  • Density, Viscosity, and Speed of Sound of (1-Octanol + 2-Methoxyethanol),(1-Octanol + N,N-Dimethylacetamide), and (1-Octanol + Acetophenone) at Temperatures of (298.15, 308.15, and 318.15) K". Journal of Chemical & Engineering Data. (wikipedia.org)
  • The Gibbs free energy, enthalpy and entropy of partitioning of 45 simple aromatic compounds (phenols, benzoic acids and acetanilides) from water to octanol and from water to cyclohexane have been determined using the filter-probe method. (mdpi.com)
  • The molecular similarity measure generally assigns a one-dimensional (1D) and/or two-dimensional (2D) descriptor-that is, molecular fingerprints based on substructure, molecular mass, number of rotatable bonds, number of hydrogen donors/acceptors of the compound, and so forth-to compounds so that the similarities of the compounds can be evaluated [ 1 - 5 ]. (hindawi.com)
  • 1) A.G. Huesgen, 'Determination of Log P for Compounds of Different Polarity Using the Agilent 1200 Infinity Series HDR-DAD Impurity Analyzer System,' Agilent Application Note, publication number 5991-4121EN, 2014. (chromatographyonline.com)
  • Numerous volatiles are released upon hydrolysis of glycoside isolates (1, 13), many of which are presumed to be acting as flavor compounds. (docecity.com)
  • found 22 volatile compounds that could could be identified, with R-(-)-1-octen-3-ol (Octanol) and phenylacetaldehyde being the major constituents of the oil. (reishiandrosesbotanicals.com)
  • In support of this RfP, a training set of potential test compounds has been selected that investigators should consider in responding to this request for proposal (Table 1). (cefic-lri.org)
  • Rapid photodecomposition on soil surfaces and in aqueous solution is an important process for the degradation of mePlant:In sugar beet, the principal metabolite is 3-methyl-6-phenyl-1,2,4-triazin-5(4 H )-one. (agropages.com)
  • γ-Terpinene (1-methyl-4-propan-2-ylcyclohexa-1,4-diene) C10H16 CAS: 99-85-4 F.W.: 136.23 g/mol 15ml (0.5 fl oz) α-Terpinene is a perfume and flavoring chemical used in the cosmetics and food industries. (consolidated-chemical.com)
  • 2. Matos J.S., Trenzado J.L, Romano E., Caro M.N., Pérez M.E. Excess molar volumes of (methyl ethanoate - 1-chlorooctane - n-alkane) ternary mixtures and their constituent binaries at 25°C // J. Solution Chem. (finechem-mirea.ru)
  • GreenScreen® assessments published after 1/1/19 expire at 5-year intervals, except for assessments of Benchmark 1 chemicals, which do not expire. (pharosproject.net)
  • Kao carefully manages chemical substances using various methods such as the PRTR System *1 and a comprehensive management system for chemicals *2 . (kao.com)
  • A statistically robust plane [log 1/IGC50 = 0.530 (log Kow) -0.890 (Elumo) -0.271, n = 50, s = 0.295, r2 = 0.855, F = 145] was found for reactive carbonyl-containing aliphatic chemicals. (qsardb.org)
  • It is an important parameter used in the assessment of environmental fate and transport of organic chemicals because the octanol phase is a surrogate for the lipid phase or organic carbon content of the environmental compartments. (hktechnical.com)
  • In this study, the effect of heterogeneous acid catalysts was investigated to product distribution by 1-octanol dehydration. (iyte.edu.tr)
  • Bi/Carbon for the oxidation of 2-octanol was investigated in a 500ml stirred tank reactor. (bl.uk)
  • The maximum conversion reached was 15% with calcined copper oxide catalyst for 1-octanol oxidation. (bl.uk)
  • JUXTAPID is a microsomal triglyceride transfer protein inhibitor indicated as an adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available, to reduce low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), apolipoprotein B (apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with homozygous familial hypercholesterolemia (HoFH) ( 1 ). (nih.gov)
  • Log Octanol-Water Partition Coef (SRC): Log Kow (KOWWIN v1.67 estimate) = 0.23 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42): Boiling Pt (deg C): 440.34 (Adapted Stein & Brown method) Melting Pt (deg C): 148.90 (Mean or Weighted MP) VP(mm Hg,25 deg C): 1.24E-007 (Modified Grain … More information on the manner in which spectra in this collection were collected can be found here. (tequilawisdom.com)
  • Octan-2-ol is an octanol carrying the hydroxy group at position 2. (laballey.com)
  • Adler EL, Woodruff RI (2000) Varied effects of 1-octanol on gap junctional communication between ovarian epithelial cells and oocytes of Oncopeltus fasciatus, Hyalophora cecropia, and Drosophila melanogaster. (yale.edu)
  • Normally one of the solvents chosen is water while the second is hydrophobic such as octanol . (chemeurope.com)
  • A gain in orientational entropy of water is the main favourable entropic contribution, supported by small gains in solute vibrational and orientational entropy but offset by unfavourable changes in the orientational entropy of octanol, the vibrational entropy of both solvents, and the positional and conformational entropy of the solute. (openrepository.com)
  • Heptanoic Acid High Purity Aroma Compound 30ml(1 fl oz) CAS: 111-14-8 Packaged in a Amber Glass Bottle 30ml (1 Fluid Ounce) Heptanoic acid , also called enanthic acid , is an organic compound composed of a seven-carbon chain terminating in a. (consolidated-chemical.com)
  • Haloalkanes are represented by general formula R - X, Where, R is an alkyl group (C n H 2n+1 ) - and X is a halogen atom (X=F, Cl, Br or I). Haloalkanes are further classified into primary, secondary, tertiary haloalkane on the basis of type of carbon atom to which the halogen is attached. (brainkart.com)
  • Product name: 1-Pentanol CAS No.: 71-41-0 Molecular Formula: C5H12O Molecular Weight: 88.15 Standard: GB2760-2007 Technical index Assay≥98%, colorless liquid. (chinachemnet.com)
  • 16. V. Consonni, R. Todeschini, M. Pavan, Structure/response correlations and similarity/diversity analysis by GETAWAY descriptors, 1-Theory of the novel 3D molecular descriptors, Journal of Chemical Information and Modeling .42;2002:682-692. (ajrconline.org)
  • The system consisted of a solvent in varying E:M ratio's, diluted in cyclohexane with 3% (v\v) 1-octanol added as modifier and a feed solution containing sulphuric acid and 100 ppm of the NH4TaF6 and NH4NbF6 complexes. (nwu.ac.za)
  • 43 IGF-1 has been reported to be a migration factor for human VSMC,37 and results from our laboratory show that IGF-1 promotes chemotaxis in rabbit aortic VSMC (Abedi H, Zachary I, un- published observations). (qrforex.com)
  • Although suited as solvent for HAc and glycolaldehyde, the benchmark TOA/1-octanol showed a low acetol distribution coefficient (0.05), which makes it less suitable for use in an integrated oxygenates extraction process. (utwente.nl)
  • Metaraminol IUPAC nomenclature 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol. (gpatindia.com)
  • An experimental rig was specifically designed and developed in this work in order to investigate the effect of surfactant (1-Octanol) on the enhancement of the heat and mass transfer in the absorption process, in addition to, the investigation of the impact of the use of magnetic stirrer inside the absorber. (scirp.org)
  • The standard microemulsion consists of 33 g SDS, 66 g butan-1-ol, 8 g n- octane in 1 L 0.05% trifluoroacetic acid (TFA). (chromatographyonline.com)
  • The ligand was unable to extract Am(III) or Eu(III) from nitric acid solutions into 1-octanol, except in the presence of a synergist at low acidity. (northumbria.ac.uk)
  • 1 Neratinib as an oral medication had demonstrated success against HER2+ type of cancer as the maleic acid salt. (cancertreatmentjournal.com)
  • The binding of phenoxazine derivatives to serum transporter protein, BSA, is correlated with their octanol-water partition coefficient, log 10 P . In addition, effect of the displacing activities of hydroxyzine and acetylsalicylic acid on the binding of phenoxazine derivatives to albumin has been studied. (ias.ac.in)
  • And the results exceeded all expectations, because the researchers observed that this substance moves quickly and spontaneously to one side of the newly-formed liposome, where it forms a droplet of 1-octanol which spontaneously separates from the host structure of its accord, within a few minutes. (nanowerk.com)
  • Figure 1 shows a typical o/w microemulsion droplet structure. (chromatographyonline.com)
  • In this paper, experimental data were obtained for absorption of water vapour into an aqueous LiBr solution with different concentrations of 1-Octanol. (scirp.org)
  • Regarding the 1-octanol/water partition coefficient, accumulation of cyclopentene in organisms is not to be expected. (europa.eu)
  • The final AM1 and PM3 MST models reproduce the experimental free energy of solvation and the octanol/water partition coefficient (log P-ow) with a root-mean-square deviation of around 0.7 kcal/mol and 0.5 (in units of log P), respectively. (ub.edu)
  • Octanol/Water partition coefficient. (chemeo.com)
  • Log (CIC50)-1 along with the hydrophobicity, the logarithm of the 1-octanol/water partition coefficient (log Kow), and R2u (GETAWAY descriptors). (ajrconline.org)
  • Log Octanol-Water Partition Coef (SRC): Log Kow (KOWWIN v1.67 estimate) = -1.65 Log Kow (Exper. (chemspider.com)
  • The octanol-water partition coefficient, K ow , describes equilibrium partitioning of a chemical between octanol and water phases. (hktechnical.com)
  • The distribution of a compound between water and octanol is used to calculate the partition coefficient, P, of that molecule (often expressed as its logarithm to the base 10, log P). Water/octanol partitioning is a relatively good approximation of the partitioning between the cytosol and lipid membranes of living systems. (wikipedia.org)
  • Termed as octanol-assisted liposome assembly (OLA), it essentially works as a bubble-blowing process at a micro scale and uses 1-octanol as a lipid-carrying solvent, which within just a few minutes, gets separated in the form of droplets, leaving behind fully matured liposomes. (nanowerk.com)
  • propofol will increase the level or effect of finerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism curred related to the use of propofol .1 Propofol is a sterile, IV, lipid-based, emulsive anesthetic agent. (jecualbellissimo.com)
  • Plasma concentrations of nicotine obtained from 1 dose (1 mg nicotine) of NICOTROL NS (nicotine nasal spray) rise rapidly, reaching maximum venous concentrations of 2-12 ng/mL in 4-15 minutes. (clustermed.info)
  • As a result, after a 1 mg dose of spray approximately 20% of the subjects reached peak nicotine concentrations similar to those seen after smoking one cigarette (7-17 ng/mL) (See Drug Abuse And Dependence Section). (clustermed.info)
  • Figure 1 below plots the mean and 5th and 95th percentile nicotine concentrations after a 1 mg single dose of the nasal spray (n=30). (clustermed.info)
  • Figure 1 : Mean and Range of the 95th and 5th Percentile Nicotine Concentrations After a 1 mg Dose of NICOTRO NS (n=30) Table 1: Trough Plasma Nicotine Concentrations after 11 Hours of Dosing With 1 mg, 2 mg and 3 mg of NICOTROL NS (nicotine nasal spray) per hour (n=16). (clustermed.info)
  • The percutaneous absorption rate of undiluted n-octanol was 50%, this was increased in squalene but decreased in castor oil or TEC. (europa.eu)
  • It is well known that small amounts of surfactants, such as 1-Octanol, in the aqueous solution can increase the absorption rate significantly. (scirp.org)
  • Quantification of significantly different concentration levels present in the water and the octanol phase for determination of log P were performed without the need of injection volume adaption. (chromatographyonline.com)
  • K ow is defined as an equilibrium ratio of the concentration in the octanol phase, C o (µg ml -1 ) and its concentration in the aqueous phase, C w (µg mL -1 ), by the equation: K ow = C o /C w . (hktechnical.com)
  • In this module, different diesel/octanol blends for the gradual introduction of climate-neutral and drop-in-capable fuels for light commercial vehicles will be investigated. (c3-mobility.de)
  • Most of the remaining substances in Table 1 are also being investigated in a separate research project that is focused on in-vitro methods for estimating fish biotransformation. (cefic-lri.org)
  • These 171 substances met categorization criteria under subsection 73(1) of CEPA or were considered a priority because of other human health or ecological concerns. (canada.ca)
  • Citral High Purity Aroma Compound 30ml (1 fl oz) CAS: 5392-40-5 Packaged in a 30ml Amber Glass Vial 100% Pure Undiluted Product For Use in Fragrance/Aroma Formulations Geranial has a strong lemon odor. (consolidated-chemical.com)
  • Formula semidesarrollada de 1,3,4hexatrieno 1 Ver respuesta Publicidad Publicidad magabaez135 está esperando tu ayuda. (bestfreenow.com)