A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly carcinogenic and mutagenic.
A naphthalene derivative with carcinogenic action.
Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.
Diethylamines are organic compounds consisting of two ethyl groups bonded to an amino nitrogen atom, with the general formula (C2H5)2NH, known for their foul odor and use as chemical intermediates in various industrial applications, but notably not associated with medical definitions unless referring to potential substance abuse or intoxication.
Dimethylamines are organic compounds that contain two methyl groups (-CH3) bonded to a nitrogen atom (N), with the general formula (CH3)2NH. They can act as secondary amines and are commonly used in chemical synthesis, but they are not typically found as natural components in the human body.
The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Organic compounds that contain the (-NH2OH) radical.
The creation of an amine. It can be produced by the addition of an amino group to an organic compound or reduction of a nitro group.
Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.
Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.
A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Inorganic or organic oxy acids of sulfur which contain the RSO2(OH) radical.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.
An analytical technique for resolution of a chemical mixture into its component compounds. Compounds are separated on an adsorbent paper (stationary phase) by their varied degree of solubility/mobility in the eluting solvent (mobile phase).
Tumors or cancer of the URINARY BLADDER.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
An island in the Greater Antilles in the West Indies. Its capital is San Juan. It is a self-governing commonwealth in union with the United States. It was discovered by Columbus in 1493 but no colonization was attempted until 1508. It belonged to Spain until ceded to the United States in 1898. It became a commonwealth with autonomy in internal affairs in 1952. Columbus named the island San Juan for St. John's Day, the Monday he arrived, and the bay Puerto Rico, rich harbor. The island became Puerto Rico officially in 1932. (From Webster's New Geographical Dictionary, 1988, p987 & Room, Brewer's Dictionary of Names, 1992, p436)
The unconsolidated mineral or organic matter on the surface of the earth that serves as a natural medium for the growth of land plants.
Products resulting from the conversion of one language to another.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
Conversion from one language to another language.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Persons living in the United States of Mexican (MEXICAN AMERICANS), Puerto Rican, Cuban, Central or South American, or other Spanish culture or origin. The concept does not include Brazilian Americans or Portuguese Americans.

Helicobacter pylori uptake and efflux: basis for intrinsic susceptibility to antibiotics in vitro. (1/96)

We previously demonstrated (M. M. Exner, P. Doig, T. J. Trust, and R. E. W. Hancock, Infect. Immun. 63:1567-1572, 1995) that Helicobacter pylori has at least one nonspecific porin, HopE, which has a low abundance in the outer membrane but forms large channels. H. pylori is relatively susceptible to most antimicrobial agents but less susceptible to the polycationic antibiotic polymyxin B. We demonstrate here that H. pylori is able to take up higher basal levels of the hydrophobic fluorescent probe 1-N-phenylnaphthylamine (NPN) than Pseudomonas aeruginosa or Escherichia coli, consistent with its enhanced susceptibility to hydrophobic agents. Addition of polymyxin B led to a further increase in NPN uptake, indicative of a self-promoted uptake pathway, but it required a much higher amount of polymyxin B to yield a 50% increase in NPN uptake in H. pylori (6 to 8 microg/ml) than in P. aeruginosa or E. coli (0.3 to 0.5 microg/ml), suggesting that H. pylori has a less efficient self-promoted uptake pathway. Since intrinsic resistance involves the collaboration of restricted outer membrane permeability and secondary defense mechanisms, such as periplasmic beta-lactamase (which H. pylori lacks) or efflux, we examined the possible role of efflux in antibiotic susceptibility. We had previously identified in H. pylori 11637 the presence of portions of three genes with homology to potential restriction-nodulation-division (RND) efflux systems. It was confirmed that H. pylori contained only these three putative RND efflux systems, named here hefABC, hefDEF, and hefGHI, and that the hefGHI system was expressed only in vivo while the two other RND systems were expressed both in vivo and in vitro. In uptake studies, there was no observable energy-dependent tetracycline, chloramphenicol, or NPN efflux activity in H. pylori. Independent mutagenesis of the three putative RND efflux operons in the chromosome of H. pylori had no effect on the in vitro susceptibility of H. pylori to 19 antibiotics. These results, in contrast to what is observed in E. coli, P. aeruginosa, and other clinically important gram-negative bacteria, suggest that active efflux does not play a role in the intrinsic resistance of H. pylori to antibiotics.  (+info)

Effect of polymorphisms on ligand binding by mouse major urinary proteins. (2/96)

Mouse urine contains an abundance of major urinary proteins, lipocalins, whose roles include slow release of semiochemicals. These proteins are highly polymorphic, with small sequence differences between individual members. In this study, we purified to homogeneity four of these proteins from two strains of inbred mice and characterized them by mass spectrometry. This analysis has led to the discovery of another variant in this group of proteins. Three of the polymorphic variants that map to the surface have no effect on the binding of a fluorescent probe in the binding cavity, but the fourth, characterized by a Phe to Val substitution in the cavity, shows a substantially lower affinity and fluorescence yield for the probe. These results are interpreted in light of the known crystal structure of the protein and molecular modeling calculations, which rationalize the experimental findings. This work raises the possibility that the calyx-binding site can show specificity for different ligands, the implications of which on pheromone binding and chemical communication are discussed.  (+info)

The micronucleus assay in human exfoliated urothelial cells: application in a genotoxicity study of workers exposed to a mineral jelly containing sodium nitrite and N-phenyl-1-naphthylamine. (3/96)

Exposure to certain chemical agents in occupational settings has been identified as carcinogenic to the human bladder. Micronucleus (MN) analysis in exfoliated urothelial cells is an interesting method for biomonitoring genetic damage in human populations. However, few studies have been performed in an occupational context. The aim of this study was to examine whether the occupational use of a mineral jelly induced a genotoxic risk for workers employed at a single factory producing bearings using the MN test on exfoliated urothelial cells. The prevalence of micronucleated exfoliated urothelial cells (MNC) was determined in 35 female workers with dermal exposure to the jelly and 41 female controls. The mean percentage of MNC (expressed as percent cells with MN per 1000 cells scored) observed in the exposed worker group was 0.46 +/- 0.11% (range 0-2.8) and in the control group 0.14 +/- 0.03% (range 0-0.8). There is a significant job effect (P = 0.0018, MANCOVA) on the prevalence of MNC, whereas age and smoking habit had no significant effect (P = 0.90 and 0.91, respectively). There is no interaction between job and smoking habit (P = 0.4421). Exposure to the mineral jelly appeared to be the main factor inducing the increased prevalence of MNC. This may be due to the presence of mutagens/carcinogens in the jelly: an aromatic amine, N-phenyl-1-naphthylamine (CAS no. 90-30-2), which is carcinogenic in mice, or sodium nitrite (CAS no. 7632-00-0), which is genotoxic in human cell systems. In conclusion, these results suggest that use of the mineral jelly could present a genotoxic risk for workers. We think that the MN assay on exfoliated cells could be valuable for biological monitoring purposes in occupational contexts as a marker of significant exposure to bladder mutagenic/carcinogenic agents.  (+info)

Specific interactions of the antimicrobial peptide cyclic beta-sheet tachyplesin I with lipopolysaccharides. (4/96)

The cyclic beta-sheet antimicrobial peptide tachyplesin I (T-SS) was found to show 280-fold higher affinity for lipopolysaccharides (LPS) compared with acidic phospholipids, whereas the linear alpha-helical peptide F5W-magainin 2 (MG2) could not discriminate between LPS and acidic phospholipids. The recognition site was the lipid A moiety and the cyclic structure was crucial to this specific binding. The cyclic structure also endowed the peptide with very rapid outer membrane (OM) permeabilization.  (+info)

Rhamnolipid stimulates uptake of hydrophobic compounds by Pseudomonas aeruginosa. (5/96)

The biodegradation of hexadecane by five biosurfactant-producing bacterial strains (Pseudomonas aeruginosa UG2, Acinetobacter calcoaceticus RAG1, Rhodococcus erythropolis DSM 43066, R. erythropolis ATCC 19558, and strain BCG112) was determined in the presence and absence of exogenously added biosurfactants. The degradation of hexadecane by P. aeruginosa was stimulated only by the rhamnolipid biosurfactant produced by the same organism. This rhamnolipid did not stimulate the biodegradation of hexadecane by the four other strains to the same extent, nor was degradation of hexadecane by these strains stimulated by addition of their own biosurfactants. This suggests that P. aeruginosa has a mode of hexadecane uptake different from those of the other organisms. Rhamnolipid also enhanced the rate of epoxidation of the aliphatic hydrocarbon alpha,omega-tetradecadiene by a cell suspension of P. aeruginosa. Furthermore, the uptake of the hydrophobic probe 1-naphthylphenylamine by cells of P. aeruginosa was enhanced by rhamnolipid, as indicated by stopped-flow fluorescence experiments. Rhamnolipid did not stimulate the uptake rate of this probe in de-energized cells. These results indicate that an energy-dependent system is present in P. aeruginosa strain UG2 that mediates fast uptake of hydrophobic compounds in the presence of rhamnolipid.  (+info)

Effect of EDTA on Salmonella enterica serovar Typhimurium involves a component not assignable to lipopolysaccharide release. (6/96)

The effect of EDTA on Salmonella enterica serovar Typhimurium was studied in different growth phases with cells grown with or without Ca(2+) and Mg(2+) supplementation. EDTA affected the outer membrane much more strongly in the early exponential phase than in the mid- or late exponential phase, as indicated by uptake of 1-N-phenylnaphthylamine (a nonpolar hydrophobic probe, M(r) 219), and detergent (SDS) susceptibility. This effect was, however, not paralleled by LPS release (determined by measuring LPS-specific fatty acids or 14C-labelled LPS in cell-free supernatants, per a standardized cell density), which remained unchanged as a function of the growth curve. The conclusion from these results is that in the early exponential phase the effect of EDTA in S. enterica involves a component that is independent of LPS release.  (+info)

Neuroendocrine response to clonidine and 8-OH-DPAT in rats following chronic administration of desipramine or sertraline. (7/96)

1. Rats were administered either desipramine (DMI) or sertraline daily at doses 7.5 mg kg-1 or 10 mg kg-1, i.p., respectively and the effects on the functional state of hypothalamic neuroendocrine control mechanisms assessed by measurements of plasma hormones following acute drug challenge. The effects of treatment on gross behaviour and brain adrenoceptor density were also determined. 2. Both DMI and sertraline caused significant reduction in activity measured as ambulation and rearing at 14 days of treatment. 3. All animals were chronically cannulated after 14 days of treatment and tested for neuroendocrine response to acute i.v. clonidine (50 micrograms kg-1) or 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT, 250 micrograms kg-1) after 21 or more days of treatment. 4. Rats treated with DMI but not sertraline showed a virtually complete suppression of the growth hormone (GH) secretion elicited by clonidine in controls, while the secretion of corticosterone was augmented. 5. Treatment with DMI but not sertraline led to a significantly greater 8-OH-DPAT-induced secretion of prolactin than in the control rats, while the plasma concentrations of corticosterone following 8-OH-DPAT were not influenced by either DMI or sertraline treatment. 6. The density (but not the affinity) of cerebral cortical binding of [3H]-dihydroalprenolol was significantly reduced by DMI treatment. 7. These results show that DMI treatment blunted the sensitivity of post-synaptic alpha 2-adrenoceptors, accompanied by complex interactions manifested as increased responsiveness of alpha 1-adrenoceptors and 5-HT1A receptors. Sertraline had no significant neurendocrine effects at a dose which significantly reduced gross activity.  (+info)

The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. (8/96)

Inhibition of human cytochrome P4502D6 (CYP2D6)-catalysed metabolism can lead to clinically significant alterations in pharmacokinetics. Since there is evidence that the selective serotonin reuptake inhibitor (SSRI) class of antidepressant drugs might inhibit CYP2D6, the effects of five SSRIs on human liver microsomal CYP2D6 activity were compared with each other and with three tricyclic antidepressant drugs. On a molar basis, paroxetine was the most potent of the SSRIs at inhibiting the CYP2D6-catalysed oxidation of sparteine (Ki = 0.15 microM), although fluoxetine (0.60 microM) and sertaline (0.70 microM) had Ki values in the same range. Fluvoxamine (8.2 microM) and citalopram (5.1 microM) also inhibited CYP2D6 activity. The major circulating metabolites of paroxetine in man produced negligible inhibition. In contrast, norfluoxetine the active metabolite of fluoxetine, was a potent CYP2D6 inhibitor (0.43 microM). CYP2D6 activity was also diminished by the tricyclic antidepressant drugs clomipramine (2.2 microM), desipramine (2.3 microM) and amitriptyline (4.0 microM). These findings suggest that compounds with SSRI activity are likely to interact with human CYP2D6 in vivo with the potential of causing drug interactions.  (+info)

1-Naphthylamine is a crystalline solid with the chemical formula C10H9N. It is an aromatic amine, which means it contains an amino group (-NH2) attached to an aromatic hydrocarbon ring. Specifically, 1-Naphthylamine is derived from naphthalene, a polycyclic aromatic hydrocarbon consisting of two benzene rings fused together.

1-Naphthylamine is a primary amine, which means the amino group is attached directly to the aromatic ring. It is a pale yellow to white crystalline powder with a melting point of 52°C (126°F) and boiling point of 280°C (536°F) at 760 mmHg.

Historically, 1-Naphthylamine was used in the manufacture of dyes and as an intermediate in the production of other chemicals. However, it is now known to be a potent human carcinogen, causing bladder cancer and other types of cancer. Therefore, its use in industrial applications has been largely discontinued.

2-Naphthylamine is a crystalline solid organic compound that is classified as a primary aromatic amine. Its chemical formula is C10H9N. It is an intensely orange-red to reddish-brown substance that is slightly soluble in water and more soluble in organic solvents.

2-Naphthylamine is produced by the reduction of 2-naphthol or its derivatives. Historically, it was used as an intermediate in the synthesis of azo dyes and other chemical compounds. However, due to its toxicity and carcinogenicity, its use has been largely discontinued in many industries.

Exposure to 2-Naphthylamine can occur through inhalation, skin contact, or ingestion, and it has been associated with an increased risk of bladder cancer and other health effects. Therefore, appropriate safety measures must be taken when handling this compound, including the use of personal protective equipment (PPE) such as gloves, lab coats, and eye protection.

Naphthalene is not typically referred to as a medical term, but it is a chemical compound with the formula C10H8. It is a white crystalline solid that is aromatic and volatile, and it is known for its distinctive mothball smell. In a medical context, naphthalene is primarily relevant as a potential toxin or irritant.

Naphthalene can be found in some chemical products, such as mothballs and toilet deodorant blocks. Exposure to high levels of naphthalene can cause symptoms such as nausea, vomiting, diarrhea, and headaches. Long-term exposure has been linked to anemia and damage to the liver and nervous system.

In addition, naphthalene is a known environmental pollutant that can be found in air, water, and soil. It is produced by the combustion of fossil fuels and is also released from some industrial processes. Naphthalene has been shown to have toxic effects on aquatic life and may pose a risk to human health if exposure levels are high enough.

I believe there may be some confusion in your question as "Organic chemistry phenomena" is a broad term and not a medical definition. However, I can provide you with an explanation of organic chemistry phenomena in a general context.

Organic chemistry is the study of carbon-containing compounds, their synthesis, reactions, properties, and structures. The term "organic" was originally used to describe biological materials, but now it refers to any compound that contains carbon atoms bonded to hydrogen atoms, except for some simple oxides, sulfides, and halides.

Organic chemistry phenomena encompass a wide range of processes and events related to organic compounds. These can include:

1. Structural properties: Understanding the arrangement of atoms in organic molecules and how they influence chemical behavior and reactivity.
2. Stereochemistry: The study of three-dimensional spatial arrangements of atoms in organic molecules, which can significantly impact their properties and biological activity.
3. Functional groups: Recognizing and understanding the behavior of specific groupings of atoms within organic molecules that determine their chemical reactivity.
4. Reaction mechanisms: Investigating and describing the step-by-step processes by which organic reactions occur, including the movement of electrons, formation and breaking of bonds, and energy changes.
5. Synthetic methodologies: Developing strategies and techniques for creating complex organic molecules from simpler precursors, often involving multiple steps and protecting group strategies.
6. Physical properties: Examining how factors such as molecular weight, polarity, solubility, and melting/boiling points affect the behavior of organic compounds in various conditions.
7. Spectroscopic analysis: Utilizing techniques like NMR (Nuclear Magnetic Resonance), IR (Infrared) spectroscopy, and mass spectrometry to analyze the structure and composition of organic molecules.
8. Biochemistry and medicinal chemistry: Exploring how organic compounds interact with biological systems, including drug design, development, and delivery.

While not a medical definition per se, understanding organic chemistry phenomena is crucial for many areas within medicine, such as pharmaceutical research, toxicology, and biochemistry.

Diethylamines are organic compounds that consist of a nitrogen atom bonded to two ethyl groups and one hydrogen atom. The chemical formula for diethylamine is (C2H5)2NH, and it is a colorless liquid with an unpleasant fishy odor. It is used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Diethylamines can also be found as byproducts in some industrial processes and are produced naturally by certain plants and animals.

Diethylamines can have stimulant effects on the central nervous system and can cause symptoms such as excitement, restlessness, and confusion. In high concentrations or with prolonged exposure, diethylamines can be toxic and may cause respiratory, cardiovascular, and neurological problems. Therefore, it is important to handle diethylamines with care and use appropriate safety measures when working with them.

Dimethylamine is an organic compound with the formula (CH3)2NH. It is a colorless gas that is highly soluble in water and polar solvents. Dimethylamine is a derivative of ammonia (NH3) in which two hydrogen atoms are replaced by methyl groups (CH3).

Dimethylamines, in medical terminology, typically refer to compounds that contain the functional group -N(CH3)2. These compounds can have various biological activities and may be used as drugs or therapeutic agents. For example, dimethylamine is a metabolite of choline, a nutrient important for brain function.

However, it's worth noting that "dimethylamines" is not typically used as a medical term to describe a specific condition or diagnosis. If you have any concerns about exposure to dimethylamine or its potential health effects, it would be best to consult with a healthcare professional.

Organic chemistry is a branch of chemistry that deals with the study of carbon-containing compounds, their synthesis, reactions, properties, and structures. These compounds can include both naturally occurring substances (such as sugars, proteins, and nucleic acids) and synthetic materials (such as plastics, dyes, and pharmaceuticals). A key characteristic of organic molecules is the presence of covalent bonds between carbon atoms or between carbon and other elements like hydrogen, oxygen, nitrogen, sulfur, and halogens. The field of organic chemistry has played a crucial role in advancing our understanding of chemical processes and has led to numerous technological and medical innovations.

Hydroxylamines are organic compounds that contain a hydroxy group (-OH) and an amino group (-NH2) in their structure. More specifically, they have the functional group R-N-OH, where R represents a carbon-containing radical. Hydroxylamines can be considered as derivatives of ammonia (NH3), where one hydrogen atom is replaced by a hydroxy group.

These compounds are important in organic chemistry and biochemistry due to their ability to act as reducing agents, nitrogen donors, and intermediates in various chemical reactions. They can be found in some natural substances and are also synthesized for use in pharmaceuticals, agrochemicals, and other industrial applications.

Examples of hydroxylamines include:

* Hydroxylamine (NH2OH) itself, which is a colorless liquid at room temperature with an odor similar to ammonia.
* N-Methylhydroxylamine (CH3NHOH), which is a solid that can be used as a reducing agent and a nucleophile in organic synthesis.
* Phenylhydroxylamine (C6H5NHOH), which is a solid used as an intermediate in the production of dyes, pharmaceuticals, and other chemicals.

It's important to note that hydroxylamines can be unstable and potentially hazardous, so they should be handled with care during laboratory work or industrial processes.

Amination is a chemical process or reaction that involves the addition of an amino group (-NH2) to a molecule. This process is often used in organic chemistry to create amines, which are compounds containing a basic nitrogen atom with a lone pair of electrons.

In the context of biochemistry, amination reactions play a crucial role in the synthesis of various biological molecules, including amino acids, neurotransmitters, and nucleotides. For example, the enzyme glutamine synthetase catalyzes the amination of glutamate to form glutamine, an essential amino acid for many organisms.

It is important to note that there are different types of amination reactions, depending on the starting molecule and the specific amino group donor. The precise mechanism and reagents used in an amination reaction will depend on the particular chemical or biological context.

Aminobiphenyl compounds are a group of chemical substances that contain two phenyl rings linked by a single carbon-nitrogen bond. The amino group (-NH2) is attached to one of the phenyl rings.

These compounds have been historically used in the manufacture of dyes and were also used as rubber accelerators. However, they have been largely phased out due to their carcinogenic properties. Exposure to certain aminobiphenyl compounds has been associated with an increased risk of bladder cancer in humans.

It is important to note that the medical definition of 'aminobiphenyl compounds' generally refers to their chemical structure and potential health hazards, rather than a specific medical condition or treatment.

Benzidines are a class of chemical compounds with the basic structure of two benzene rings linked by a central nitrogen atom. The term "benzidine" can refer specifically to the parent compound, but it is more commonly used as a general term for a group of related compounds known as benzidine congeners or benzidine derivatives.

Benzidines are primarily used in the manufacture of dyes and pigments, although they have also been used in some industrial and laboratory applications. Exposure to benzidines has been linked to an increased risk of bladder cancer and other health problems, so their use is regulated in many countries.

It's worth noting that the medical definition of "benzidines" primarily focuses on their chemical structure and potential health effects, rather than their specific medical uses or applications.

Amines are organic compounds that contain a basic nitrogen atom with a lone pair of electrons. They are derived from ammonia (NH3) by replacing one or more hydrogen atoms with alkyl or aryl groups. The nomenclature of amines follows the substitutive type, where the parent compound is named as an aliphatic or aromatic hydrocarbon, and the functional group "amine" is designated as a suffix or prefix.

Amines are classified into three types based on the number of carbon atoms attached to the nitrogen atom:

1. Primary (1°) amines: One alkyl or aryl group is attached to the nitrogen atom.
2. Secondary (2°) amines: Two alkyl or aryl groups are attached to the nitrogen atom.
3. Tertiary (3°) amines: Three alkyl or aryl groups are attached to the nitrogen atom.

Quaternary ammonium salts have four organic groups attached to the nitrogen atom and a positive charge, with anions balancing the charge.

Amines have a wide range of applications in the chemical industry, including pharmaceuticals, dyes, polymers, and solvents. They also play a significant role in biological systems as neurotransmitters, hormones, and cell membrane components.

I'm sorry for any confusion, but "sulfonic acids" are not a medical term. They are a type of compound in chemistry, specifically strong organic acids that contain the functional group -SO3H. Sulfonic acids are widely used in industry and research, including the production of detergents, dyes, and pharmaceuticals.

If you have any questions related to medical terminology or concepts, please don't hesitate to ask!

Carcinogens are agents (substances or mixtures of substances) that can cause cancer. They may be naturally occurring or man-made. Carcinogens can increase the risk of cancer by altering cellular DNA, disrupting cellular function, or promoting cell growth. Examples of carcinogens include certain chemicals found in tobacco smoke, asbestos, UV radiation from the sun, and some viruses.

It's important to note that not all exposures to carcinogens will result in cancer, and the risk typically depends on factors such as the level and duration of exposure, individual genetic susceptibility, and lifestyle choices. The International Agency for Research on Cancer (IARC) classifies carcinogens into different groups based on the strength of evidence linking them to cancer:

Group 1: Carcinogenic to humans
Group 2A: Probably carcinogenic to humans
Group 2B: Possibly carcinogenic to humans
Group 3: Not classifiable as to its carcinogenicity to humans
Group 4: Probably not carcinogenic to humans

This information is based on medical research and may be subject to change as new studies become available. Always consult a healthcare professional for medical advice.

The urinary bladder is a muscular, hollow organ in the pelvis that stores urine before it is released from the body. It expands as it fills with urine and contracts when emptying. The typical adult bladder can hold between 400 to 600 milliliters of urine for about 2-5 hours before the urge to urinate occurs. The wall of the bladder contains several layers, including a mucous membrane, a layer of smooth muscle (detrusor muscle), and an outer fibrous adventitia. The muscles of the bladder neck and urethra remain contracted to prevent leakage of urine during filling, and they relax during voiding to allow the urine to flow out through the urethra.

Paper chromatography is a type of chromatography technique that involves the separation and analysis of mixtures based on their components' ability to migrate differently upon capillary action on a paper medium. This simple and cost-effective method utilizes a paper, typically made of cellulose, as the stationary phase. The sample mixture is applied as a small spot near one end of the paper, and then the other end is dipped into a developing solvent or a mixture of solvents (mobile phase) in a shallow container.

As the mobile phase moves up the paper by capillary action, components within the sample mixture separate based on their partition coefficients between the stationary and mobile phases. The partition coefficient describes how much a component prefers to be in either the stationary or mobile phase. Components with higher partition coefficients in the mobile phase will move faster and further than those with lower partition coefficients.

Once separation is complete, the paper is dried and can be visualized under ultraviolet light or by using chemical reagents specific for the components of interest. The distance each component travels from the origin (point of application) and its corresponding solvent front position are measured, allowing for the calculation of Rf values (retardation factors). Rf is a dimensionless quantity calculated as the ratio of the distance traveled by the component to the distance traveled by the solvent front.

Rf = (distance traveled by component) / (distance traveled by solvent front)

Paper chromatography has been widely used in various applications, such as:

1. Identification and purity analysis of chemical compounds in pharmaceuticals, forensics, and research laboratories.
2. Separation and detection of amino acids, sugars, and other biomolecules in biological samples.
3. Educational purposes to demonstrate the principles of chromatography and separation techniques.

Despite its limitations, such as lower resolution compared to high-performance liquid chromatography (HPLC) and less compatibility with volatile or nonpolar compounds, paper chromatography remains a valuable tool for quick, qualitative analysis in various fields.

Urinary Bladder Neoplasms are abnormal growths or tumors in the urinary bladder, which can be benign (non-cancerous) or malignant (cancerous). Malignant neoplasms can be further classified into various types of bladder cancer, such as urothelial carcinoma, squamous cell carcinoma, and adenocarcinoma. These malignant tumors often invade surrounding tissues and organs, potentially spreading to other parts of the body (metastasis), which can lead to serious health consequences if not detected and treated promptly and effectively.

I believe there might be a misunderstanding in your question. "Dogs" is not a medical term or condition. It is the common name for a domesticated carnivore of the family Canidae, specifically the genus Canis, which includes wolves, foxes, and other extant and extinct species of mammals. Dogs are often kept as pets and companions, and they have been bred in a wide variety of forms and sizes for different purposes, such as hunting, herding, guarding, assisting police and military forces, and providing companionship and emotional support.

If you meant to ask about a specific medical condition or term related to dogs, please provide more context so I can give you an accurate answer.

I'm sorry for any confusion, but "Puerto Rico" is not a medical term. It is a territorial possession of the United States, located in the northeastern Caribbean Sea. It includes the main island of Puerto Rico and various smaller islands. If you have any questions about a medical topic, please provide more details so I can try to help answer your question.

I'm sorry for any confusion, but "soil" is not a term that has a medical definition. Soil is defined as the top layer of earth in which plants grow, a mixture of organic material, clay, sand, and silt. If you have any questions related to medicine or health, I would be happy to try to help answer them for you.

I believe there may be some confusion in your question as "translations" is not a term that has a specific medical definition. However, if you are referring to the process of "translation" in the context of medicine and biomedical research, it refers to the process of converting scientific findings or medical information from one language to another, while maintaining accuracy, clarity, and the original meaning. This is particularly important in the field of international clinical trials, medical publications, and cross-cultural healthcare communication.

If you meant something different by 'translations', please provide more context so I can give a more accurate response.

Public health is defined by the World Health Organization (WHO) as "the art and science of preventing disease, prolonging life and promoting human health through organized efforts of society." It focuses on improving the health and well-being of entire communities, populations, and societies, rather than individual patients. This is achieved through various strategies, including education, prevention, surveillance of diseases, and promotion of healthy behaviors and environments. Public health also addresses broader determinants of health, such as access to healthcare, housing, food, and income, which have a significant impact on the overall health of populations.

In the context of medicine, "translating" often refers to the process of turning basic scientific discoveries into clinical applications that can directly benefit patients. This is also known as "translational research." It involves taking findings from laboratory studies and experiments, and finding ways to use that knowledge in the development of new diagnostic tools, treatments, or medical practices.

The goal of translation is to bridge the gap between scientific discovery and clinical practice, making sure that new advances in medicine are both safe and effective for patients. This process can be complex and challenging, as it requires collaboration between researchers, clinicians, regulatory agencies, and industry partners. It also involves rigorous testing and evaluation to ensure that any new treatments or interventions are both safe and effective.

A questionnaire in the medical context is a standardized, systematic, and structured tool used to gather information from individuals regarding their symptoms, medical history, lifestyle, or other health-related factors. It typically consists of a series of written questions that can be either self-administered or administered by an interviewer. Questionnaires are widely used in various areas of healthcare, including clinical research, epidemiological studies, patient care, and health services evaluation to collect data that can inform diagnosis, treatment planning, and population health management. They provide a consistent and organized method for obtaining information from large groups or individual patients, helping to ensure accurate and comprehensive data collection while minimizing bias and variability in the information gathered.

Hispanic Americans, also known as Latino Americans, are individuals in the United States who are of Spanish-speaking origin or whose ancestors came from Spain, Mexico, Cuba, the Caribbean, Central and South America. This group includes various cultures, races, and nationalities. It is important to note that "Hispanic" refers to a cultural and linguistic affiliation rather than a racial category. Therefore, Hispanic Americans can be of any race, including White, Black, Asian, Native American, or mixed races.

... is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It ... At 200 °C in sulfuric acid, it converts to 1-naphthol. The sulfonic acid derivatives of 1-naphthylamine are used for the ... Upon treatment with the bis(diazonium) derivative of benzidine, 1-aminonaphthalene-4-sulfonic acid gives Congo red. It is ... It can be prepared by reducing 1-nitronaphthalene with iron and hydrochloric acid followed by steam distillation. Oxidizing ...
... is used in the nitrate reductase test to form a red precipitate of Prontosil by reacting with a ... N,N-Dimethyl-1-naphthylamine is an aromatic amine. It is formally derived from 1-naphthylamine by replacing the hydrogen atoms ... "N,N-dimethylnaphthalen-1-amine". ChemSpider. Retrieved 15 April 2010. "D4011 N,N-Dimethyl-1-naphthylamine, ≥98.0% (GC)". Sigma- ... 1-Naphthyl compounds, Dimethylamino compounds, All stub articles, Amine stubs). ...
... was previously used as a dye precursor and rubber antioxidant in the 1930s, 40s and 50s. Dupont stopped using ... 2-Naphthylamine is found in cigarette smoke and suspected to contribute to the development of bladder cancer. It is activated ... 2-Naphthylamine is prepared by heating 2-naphthol with ammonium zinc chloride to 200-210 °C, the Bucherer reaction. Its acetyl ... 2-Naphthylamine is one of two isomeric aminonaphthalenes, compounds with the formula C10H7NH2. It is a colorless solid, but ...
... can refer to either of two isomeric chemical compounds: 1-Naphthylamine 2-Naphthylamine This set index article ...
Naphthylamines, Anilines). ... 1-Naphthylamine is reacted with cyanogen bromide to give 2. ... 38 (1): 33-8. doi:10.1111/j.1365-2125.1994.tb04318.x. PMC 1364834. PMID 7946934. Schäbitz WR, Li F, Fisher M (July 2000). "The ... N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist". Journal of ... N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist". Journal of ...
Bladder cancer can be induced in rats, but 2-naphthylamine is a very weak carcinogen in rats due to their urine pH, urination ... In mice, 2-naphthylamine caused an increase in hepatomas, liver adenomas, and cholangiomas. Videbaek, A.; Kaae, S. (1954). "2- ... Hicks, R M; Wright, R; Wakefield, J S J (1982). "The induction of rat bladder cancer by 2-naphthylamine". British Journal of ... Chlornaphazine, a derivative of 2-naphthylamine, is a nitrogen mustard that was developed in the 1950s for the treatment of ...
However, it is a weaker bidentate ligand as the nitrogen atom in the naphthylamine group is weakly coordinating due to the ... ethylenediamine undergoes most reactions typical to naphthylamine and primary amines such as diazotation. Similar to its analog ... N-(1-Naphthyl)ethylenediamine is an organic compound. It is commercially available as part of Griess reagents, which find ... This compound can be prepared by the reaction of 1-naphthylamine with 2-chloroethanamine. It is commercially available as the ...
16 (1): 68-84. doi:10.1007/BF00306212. PMID 5717700. S2CID 41983162. Stains File entry (Articles without KEGG source, Articles ... Sudan Black is formed by coupling of diazotized 4-phenylazo-1-naphthylamine with 2,3-dihydro-2,2-dimethyl-1H-perimidine. ... Therefore, the main product expected was 2,3-dihydro-2,2dimethyl-6-[(4-phenylazo-1-naphthalenyl)-azo]-1H-perimidine. However ... 1, SiO2) in thin Layer Chromatography). The above described product indeed turned out to be SSB-II which comprises up to 60% of ...
It is an intermediate in the production of naphthylamine, a precursor to dyes. Toxic. Booth, Gerald (2005). "Nitro Compounds, ... 1-Nitronaphthalene is an organic compound with the formula C10H7NO2. It is one of two isomers of nitronaphthalene. A pale ... yellow, sublimable solid, 1-nitronaphthalene is the main product of the direct nitration of naphthalene. ...
Koe, BK (September 1983). "Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake ...
Sarges R, Koe BK, Weissman A, Schaefer JP (December 1974). "Blockade of heart 3H-norepinephrine up-take by 4-phenyl-1- ... Welch WM, Kraska AR, Sarges R, Koe BK (November 1984). "Nontricyclic antidepressant agents derived from cis- and trans-1-amino- ... Cyproheptadine [4-(5H-dibenz-[a,d]cyclohepten-5-ylidine)-1-methylpiperidine] Dasotraline Desmethylsertraline EXP-561 (1-amino-4 ... CP-51,974-1). Sertraline has been called "3,4-dichloro-tametraline". This is correct but it is an oversimplification in the ...
51 (1): 273-282. doi:10.1002/cber.19180510132. Homer W. J. Cressman (1947). "N-Methyl-1-Naphthylcyanamide". Org. Synth. 27: 56 ... An example is the reaction of N,N-dimethyl-1-naphthylamine: These days, most chemist have replaced cyanogen bromide reagent ... 1984, 49, 11, 2081-2082 Publication Date:June 1, 1984 https://doi.org/10.1021/jo00185a072 March, Jerry (1985), Advanced Organic ...
2-Aminoindane 2-Aminotetralin 2-Naphthylamine Hathaway BA, Nichols DE, Nichols MB, Yim GK (May 1982). "A new, potent, ... 2-Amino-1,2-dihydronapthalene (2-ADN), also known as 2-aminodilin (2-AD), is a stimulant drug. It is a rigid analogue of ... It is closely related to 2-aminotetralin (2-amino-1,2,3,4-tetrahydronaphthalene), which also substitutes for amphetamine, and ... conformationally restricted analogue of amphetamine: 2-amino-1,2-dihydronaphthalene". Journal of Medicinal Chemistry. 25 (5): ...
1 Squadron) and CAC Sabres of No. 78 Wing carried out ground attack missions against the guerrillas. The Royal Australian Navy ... 1 Squadron (Avro Lincoln bombers) and No. 38 Squadron (C-47 transports). In 1955, the RAAF extended Butterworth air base, from ... doi:10.1007/978-1-4899-0339-6. ISBN 9780306409738. S2CID 29278382. It was the British who were actually the first to use ... 1): 53-74. Newsinger 2015, p. 41. Eric Stahl, "Doomed from the Start: A New Perspective on the Malayan Insurgency" (master's ...
... or 4-methylquinoline 1-Naphthylamine 2-Naphthylamine Quinaldine This set index page lists chemical structure articles ...
... it is suspected that metabolic hydrolysis of the amide group of FDU-NNE1 will release 1-naphthylamine, a known carcinogen. 5F- ...
Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 260 Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide ... Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V16 987 (1995) Cunningham, A. L., and J. V. Hurley. "Alpha‐ ... 1981., p. 1-2 NIOSH. NIOSH Pocket Guide to Chemical Hazards & Other Databases. U.S. Department of Health & Human Services, ... The usual method is the reaction of 1-naphthylamine hydrochloride with ammonium thiocyanate: [C10H7NH3]Cl + NH4SCN → C10H7NHC(S ...
For better differentiation, it is dipped in 1% acetic acid for 10-20 minutes or 30 sec until the colors are pure. This might ... 73 (1): 32-8. doi:10.1562/0031-8655(2001)073. 2.0.CO;2. PMID 11202363. S2CID 198157623. Kanitz, Andreas; Hartmann, Horst (1999 ... The Nile blue staining, according to Kleeberg, uses the following chemicals: Nile Blue A 1% acetic acid Glycerol or glycerol ... 2-nitrosophenols with 1-naphthylamine, 3-(dialkylamino)phenols with N-alkylated 4-nitroso-1-naphtylamines, or N,N-dialkyl-1,4- ...
243: 1-13. doi:10.1016/j.forsciint.2014.03.013. PMID 24769262. Gamage TF, Farquhar CE, Lefever TW, Marusich JA, Kevin RC, ... 33 (1): 165-169. doi:10.1007/s11419-014-0246-5. S2CID 13524298. v t e (Articles with short description, Short description ... It is suspected that metabolic hydrolysis of the amide group of NNE1 may release 1-naphthylamine, a known carcinogen, given the ... New Zealand Government Gazette, Notice Number 7051, 1 November 2012 Sasaki C, Saito T, Shinozuka T, Irie W, Murakami C, Maeda K ...
N-dimethyl-1-naphthylamine More than 400 other chemical compounds "Empirical formula search for C12H13N". ChemSpider. Retrieved ...
This diamine is used in place of the simpler and cheaper 1-naphthylamine because the latter is a potent carcinogen and moreover ... The most common arrangements use sulfanilamide and N-(1-naphthyl)ethylenediamine: a typical commercial Griess reagent contains ... 1-naphthyl)ethylenediamine in an azo coupling reaction, forming a pink-red azo dye. Using a spectrophotometer, it is possible ... 0.2% N-(1-naphthyl)ethylenediamine dihydrochloride, and 2% sulfanilamide in 5% phosphoric acid. ...
10 (1): 137-147. doi:10.1002/dta.2262. PMC 5785468. PMID 28834241. "Cannabinoider föreslås bli klassificerade som hälsofarlig ... it is suspected that metabolic hydrolysis of the amide group of MN-18 may release 1-naphthylamine, a known carcinogen. MN-18 ...
Condensation of Michler's ketone with N-phenyl-1-naphthylamine gives the dye Victoria Blue B (CAS#2580-56-5, CI Basic Blue 26 ... Charles D. DeBoer, Nicholas J. Turro, and George S. Hammond (1973). "cis- and trans-1,2-Divinylcyclobutane". Organic Syntheses ... absorbs intensely at 366 nm and effectively sensitizes photochemical reactions such as the dimerization of butadiene to give 1, ...
... it is suspected that metabolic hydrolysis of the amide group of 5F-PCN may release 1-naphthylamine, a known carcinogen. ...
5F-ADBICA 5F-SDB-006 AM-2201 FDU-NNE1 FUB-144 MMB-2201 NNE1 PX-1 "5F-NNEI". Southern Association of Forensic Scientists. ... it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release 1-naphthylamine, a known carcinogen. ...
2-naphthylamine MeSH D04.615.638.870 - 1-naphthylisothiocyanate MeSH D04.615.638.900 - naphthylvinylpyridine MeSH D04.615. ... vitamin k 1 MeSH D04.615.638.721.374.844 - vitamin k 2 MeSH D04.615.638.721.374.922 - vitamin k 3 MeSH D04.615.638.845 - 1- ... naphthylamine MeSH D04.615.638.845.800 - sertraline MeSH D04.615.638.850 - ... 10-dimethyl-1,2-benzanthracene MeSH D04.615.149.500 - methylcholanthrene MeSH D04.615.149.700 - perylene MeSH D04.615.181.384 ...
Naphthylamines). ... 1 April 2006. (CS1 errors: periodical ignored, CS1: long volume ... The extinction coefficient for trypan blue is 6⋅104 M−1 cm−1 at 607 nm in methanol. Trypan red and trypan blue were first ...
2-Naphthylamine Nickel compounds 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) N-Nitrosonornicotine (NNN) 2,3,4,7,8- ... 2-naphthylamine) Chlorambucil Bis(chloromethyl)ether Chloromethyl methyl ether Chromium(VI) (Hexavalent chromium) compounds ... Substances, mixtures, and exposure circumstances in this list have been classified as group 1 by the International Agency for ... "List of Classifications, Agents classified by the IARC Monographs, Volumes 1-124". IARC Monographs on the Evaluation of Risk to ...
Naphthylamines, Diamines). ... 1,5-Diaminonaphthalene is an organic compound with the formula ... It is prepared by reduction of 1,5-dinitronaphthalene, which in turn is obtained with the 1,8-isomers by nitration of 1- ... It can also be prepared by treatment of 1,5-dihydroxynaphthalene with ammonium sulfite. It is a precursor to naphthalene-1,5- ... Bernès, Sylvain; Pastrana, Modesto Rodríguez; Sánchez, Enrique Huerta; Pérez, René Gutiérrez (12 December 2003). "1,5- ...
1-Naphthylamine is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It ... At 200 °C in sulfuric acid, it converts to 1-naphthol. The sulfonic acid derivatives of 1-naphthylamine are used for the ... Upon treatment with the bis(diazonium) derivative of benzidine, 1-aminonaphthalene-4-sulfonic acid gives Congo red. It is ... It can be prepared by reducing 1-nitronaphthalene with iron and hydrochloric acid followed by steam distillation. Oxidizing ...
Literature References: Prepd by sulfonation of 2-naphthylamine: Tinker, Hansen, US 1969189 (1934 to du Pont). Utilization in ...
1 Naphthylamine - Explore the topic 1 Naphthylamine through the articles written by the best experts in this field - both ... Naphthylamine ( 10 ) by the regioselective deacylation of N , N -dimethyl-2,4-bis(trifluoroacetyl)-1-Naphthylamine with ... Naphthylamine) nanohybrid with size in the range of 140-200 nm. Cyclic voltammetry studies showed that the nanohybrid was more ... Naphthylamine has been found to be highly efficient in the Ir-catalyzed asymmetric hydrogenation of various 3-aryl-2H-1,4- ...
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... naphthylamine and sulphanilic acid in acetic acid is used for the detection of$\mathrm{N}_{2} \mathrm{O}$$\mathrm{NO}_{3}^{-}$ ... naphthylamine and sulphanilic acid in acetic acid is used for the detection of. ... naphthylamine and sulphanilic acid in acetic acid is used for the detection of ...
... crystal structure with free radical scavenging activity and theoretical studies of Schiff bases derived from 1-naphthylamine, 2 ... Segun Daniel Oladipo (1) , Tunde Lewis Yusuf (2,*) , Sizwe Joshua Zamisa (3) , Gideon Femi Tolufashe (4) , Kolawole Ayodapo ... 1- The article processing fee will not be charged from the articles containing the single-crystal structure characterization or ... The final R1 was 0.0337 (I≥2u(I)) and wR2 was 0.0927 (all data). The free radical scavenging activities of all three compounds ...
2-Naphthylamine. 2000 µg/mL. CAS #: 91-59-8 * 2-Nitroaniline. 2000 µg/mL. CAS #: 88-74-4 ...
... the comment provided by Latvia with regard to its notification of final regulatory action on 2-naphthylamine. ... the comment provided by Latvia with regard to its notification of final regulatory action on 2-naphthylamine. ... 1. The following results of the first meeting of the Conference of the Parties are relevant to the first meeting of the ... 1. At its first meeting, the interim Chemical Review Committee developed a flow chart of the process and explanatory notes for ...
1-Naphthol has been used as a prooxidant to analyze its ability to induce hemolysis in a zebrafish G6PD (glucose-6-phosphate ... The decomposition of 1-naphthol in aqueous solutions on exposure to gamma radiation has been studied.. The ability of biochar ... It undergoes hydrogenation in the presence of a rhodium catalyst to form cis,cis 1-decalol.. This product is a certified ... 1-Naphthol is a hydroxyl-aromatic compound. Its thermodynamic properties such as heat capacity, sublimation pressure, vapor ...
2-Naphthylamine (2-aminonaphthalene) (91-59-8). N-Nitrosodibutylamine (924-16-3). N-Nitrosodiethylamine (55-18-5). N- ... 1,4-Phenylenediamine (106-50-3). 2-Picoline (109-06-8). o-Toluidine (95-53-4). Cat.# 32460: Methapyrilene. 2000 µg/mL in ... 1,3,5-Trinitrobenzene (99-35-4). Cat.# 31879: Benzoic acid. 2000 µg/mL in methylene chloride, 1 mL/ampul. Benzoic acid (65-85-0 ... Acrylamide (79-06-1). Benzidine (92-87-5). n-Decane (C10) (124-18-5). Dibenz(a,h)acridine (226-36-8). 2,3-Dichloroaniline (608- ...
2-Naphthylamine. 2-Nitroaniline (o-Nitroaniline). 2-Nitrophenol (o-Nitrophenol). 2-Picoline. ... Table B-1.. Sampling Summary of the Public Water Supply System on Isla de Vieques, Puerto Rico. Name. Location. Use. Sampling. ... OP-1 is the observation tower and the closest drinking water sample to the LIA. This sample may include rainfall collection or ... Table E-1.. Chemicals Detected in Historical Drinking Water Samples. Chemical. Chemical Concentration (ppb). Drinking Water ...
... naphthylamine (HNN). In the absence of SDS, the estimated extraction constants of the three ligands revealed that the ... Requires Authentication Unlicensed Licensed May 1, 2013 The Detergency of Surfactant Mixtures and Bentonites on Cotton Fabric. ... Requires Authentication Unlicensed Licensed May 1, 2013 Softening Effect of Bentonite and Redeposition of Solid Impurities on ... Requires Authentication Unlicensed Licensed May 1, 2013 Physicochemical Characterization and in vivo Skin Performance of a ...
2-naphthylamine and benzidine) in the muscle tissue of fish. There were marked seasonal variations in the aromatic amine levels ... was free from 2-naphthylamine and benzidine in winter and autumn. The variation may be related to the feeding habits or the ... 2-naphthylamine and benzidine in the muscle tissue of 4 types of fish: Tilapia sp. and Claris sp. from Lake Edku and Mugil sp. ... 2-naphthylamine and benzidine) in the muscle tissue of fish. There were marked seasonal variations in the aromatic amine levels ...
1-(3-CHLOROPHENYL)CYCLOPROPANECARBOXYLIC ACID;1-(3-CHLOROPHENYL)CYCLOPROPANE-1-CARBOXYLIC ACID;AKOS BBV-004387 ... Previous: CAS:124184-67-4 , D-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-methyl ester , C10H17NO6 ...
... and the confirmed bladder carcinogenicity of the related compound 2-naphthylamine in humans. ... 1-Naphthyl)ethylenediamine dihydrochloride, a diagnostic reagent derived from 1-naphthylamine, was selected for bioassay by the ... and the confirmed bladder carcinogenicity of the related compound 2-naphthylamine in humans. ... Bioassay of N-(1-Naphthyl)ethylenediamine Dihydrochloride for Possible Carcinogenicity. CASRN: 1465-25-4 Chemical Formula: ...
N-Phenyl-2-naphthylamine (135-88-6) 2 alternate names. 5 safety hazards 3 suppliers ... Chronic toxicity of Yellow AB (1-phenylazo-2-naphthylamine) and Yellow OB (1-o-tolylazo-2-naphthylamine) (Toxicology and ... N,N-Diphenyl-p-phenylenediamine (74-31-7, 27137-31-1) 2 alternate names ...
beta-Naphthylamine. 91-94-1. 3,3-Dichlorobenzidine (and its salts). 92-06-8. m-Terphenyl. ...
Naphthylamine - 98% (Reagent for Gold). 0 out of 5. Add to cart Add to Wishlist ... 1-Heptane sulphonic acid sodium salt anhydrous A.R. 0 out of 5 ... 1-Butane sulphonic acid sodium salt A.R. 0 out of 5 ...
1H NMR SDBS-NMR-HSP-47-710. Raman SDBS-RM-01-02816. ... N,N-dimethyl-1-naphthylamine. Sample: Molecular Formula. C12H13 ... InChI=1S/C12H13N/c1-13(2)12-9-5-7-10-6-3-4-8-11(10)12/h3-9H,1-2H3. ...
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. ...
CAS Type 1 Name. 1-Naphthalenamine,1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-, (1S-cis)-. Previous Indexing. 1- ... Naphthylamine/analogs & derivatives (1983-1998). Public MeSH Note. 99; SERTRALINE was indexed under 1-NAPHTHYLAMINE/analogs & ...
N-phenyl-1-naphthylamine ... Applications: This product is widely used in natural and ... PAN/A Torch China, RUBBER ANTIOXIDANT P A N ( A ) Chemical Name: N-Phenyl-l-naphthylamine Molecular Formulafree amine( ... RUBBER ANTIOXIDANT PAN ( A ) Chemical Name: N-Phenyl-l-naphthylamine Molecular Formula: C16H13N Molecular Weight: 219.29 ... 1 USD. Rubber Chemicals-Rubber Antioxidant A/PAN. Yellow or purple flake. Melting point 62° C, flash point 188° C, gravity 1.16 ...
NFCs products, including Sulfanilic Acid (CAS#121-57-3) and PANA (N-Phenyl-1-naphthylamine, CAS#90-30-2), are sold worldwide ...
Articles in Volume - 28, Issue - 1. Online Since: Tuesday, Feb 09, 2021 Published on: Wednesday, Jul 01, 2015 [ Views: 6240 ]. ... Fluorescence Quenching of 1-Naphthylamine by γ-Picoline in Micellar Medium Author(s): Anita Xess;Prabhati Padhan;Debananda Sahu ... Cite: Xess, Padhan, Sahu, and Behera (2015). Fluorescence Quenching of 1-Naphthylamine by γ-Picoline in Micellar Medium. ... Journal of Ravishankar University (Part-B: Science), 28(1), pp. 1-10. ...
α-naphthylamine. InChi-Key. RUFPHBVGCFYCNW-UHFFFAOYSA-N. Registry No.. 134-32-7. ... System: decane/1-naphthalenamine. Use the dropdown to view details on the components ...
d (1/. T. ). , also at the reference temperature. References. * Abraham, M. H., Andonian-Haftvan, J., Whiting, G. S., Leo, A ... Henrys Law Constants → Organic species with nitrogen (N) → Amines (C, H, N) → 1-naphthylamine. FORMULA:. C10H9N. ...
  • A bulk powder sample of an additive contained approximately 1 part per million of alpha-naphthylamine (134327). (cdc.gov)
  • The sulfonic acid derivatives of 1-naphthylamine are used for the preparation of azo dye. (wikipedia.org)
  • Poly( 1 - Naphthylamine ) (PNA) has been one of the seldom explored polyaniline (PANI) derivatives in spite of its versatile electrochromic and optoelectronic properties. (idexlab.com)
  • N-(1-Naphthyl)ethylenediamine dihydrochloride, a diagnostic reagent derived from 1-naphthylamine, was selected for bioassay by the National Cancer Institute because of the suspected carcinogenicity of its parent compound, and the confirmed bladder carcinogenicity of the related compound 2-naphthylamine in humans. (nih.gov)
  • We estimated pollution in Lake Edku and the Mediterranean Sea, El-Maadiya Region, with 3 aromatic amines (1-naphthylamine, 2-naphthylamine and benzidine) in the muscle tissue of fish. (who.int)
  • Nous avons réalisé une estimation de la pollution dans le lac Edkou et en Méditerranée (région d'El-Maadiya), sur la base de trois amines aromatiques (1-naphthylamine, 2-naphthylamine et benzidine) dans les tissus musculaires de poissons. (who.int)
  • Structures of IARC Group 1 aromatic amines, drugs that are urothelial cancer in humans ( IARC, metabolized to Group 1 aromatic amines, and aristolochic acids. (who.int)
  • 1. Introduction amines and vinyl chloride) ( Gochfeld, 2005a,b ). (cdc.gov)
  • The present research also discloses that these newly developed phosphine-aminophosphine ligand s are more efficient than that derived from (S)- 1 -phenyl ethyl amine, suggesting that the increased rigidity conferred by a cyclohexyl fragment in these phosphine-aminophosphine ligand s has a positive effect in the asymmetric induction. (idexlab.com)
  • Three Schiff bases 1-(4-chlorophenyl)- N -(naphthalen-1-yl)methanimine (1), 1-(4-methoxy phenyl)- N -(naphthalen-1-yl)methanimine (2), and 1-(4-chlorophenyl)- N -(2,6-diisopropyl phenyl)methanimine (3) were synthesized and characterized by elemental analysis, 1 H and 13 C NMR, FT-IR and UV-Visible spectroscopic techniques. (eurjchem.com)
  • Antioxidant N-phenyl-1-naphthylamine( A/pan) For Producing Rubber And Tyre , Find Complete Details about Antioxidant N-phenyl-1-naphthylamineUsed in tyres, rubber belts, rubber shoes and so on. (yashodadevelopers.in)
  • NFC's products, including Sulfanilic Acid (CAS#121-57-3) and PANA (N-Phenyl-1-naphthylamine, CAS#90-30-2), are sold worldwide through offices in the United States, Europe, and China. (socma.org)
  • Sodium in boiling amyl alcohol reduces the unsubstituted ring, giving tetrahydro-1-naphthylamine. (wikipedia.org)
  • Unsymmetrical hybrid chiral phosphine-aminophosphine ligand derived from 1 ,2,3,4-tetrahydro- 1 - Naphthylamine has been found to be highly efficient in the Ir-catalyzed asymmetric hydrogenation of various 3-aryl-2H- 1 ,4-benzoxazines, providing good enantioselectivities (up to 95% ee) and high catalytic activity (S/C up to 5000). (idexlab.com)
  • A series of new chiral phosphine-aminophosphine ligand s [(R)-HW-Phos] has been prepared from (R)-l.,2,3,4-tetrahydro- 1 - Naphthylamine through a two-step procedure, and successfully applied in the rhodium -catalyzed asymmetric hydrogenation of various functionalized olefins such as alpha-enol ester phosphonates, alpha-enamido phosphonates, (Z)-beta-(acylamino)acrylates and so on. (idexlab.com)
  • We have recently reported a new chiral 1 ,2,3,4-tetrahydro- 1 - Naphthylamine -derived phosphine- phosphoramidite ligand , (R-c,R-a)-THNAPhos, that is highly efficient in the rhodium -catalyzed asymmetric hydrogenation of a broad range of alpha-enol ester phosphonates. (idexlab.com)
  • An important derivative is naphthionic acid (1-aminonaphthalene-4-sulfonic acid), which is produced by heating 1-naphthylamine and sulfuric acid to 170-180 °C in the presence of crystallized oxalic acid. (wikipedia.org)
  • Upon treatment with the bis(diazonium) derivative of benzidine, 1-aminonaphthalene-4-sulfonic acid gives Congo red. (wikipedia.org)
  • الخلاصـة: قاس الباحثون في بحيرة إدكو والبحر المتوسط، في منطقة المعدية، ثلاثة مركبات أمينية أروماتية هي (1-naphthylamine 2-naphthylamine, benzidine) في أنسجة عضلات السمك. (who.int)
  • It can be prepared by reducing 1-nitronaphthalene with iron and hydrochloric acid followed by steam distillation. (wikipedia.org)
  • Chromic acid converts it into 1-naphthoquinone. (wikipedia.org)
  • At 200 °C in sulfuric acid, it converts to 1-naphthol. (wikipedia.org)
  • 1-Naphthol is a hydroxyl-aromatic compound. (sigmaaldrich.com)
  • The compound was administered in the diet for 104 weeks, followed by an observation period of 4 weeks for high dose rats, 3 weeks for low dose rats, low dose female mice, and high dose female mice, and 1 week for high dose male mice. (nih.gov)
  • This product is a certified reference material (CRM) certified to International Standards BS EN ISO / IEC 17025 and ISO 17034 under UKAS accreditation. (sigmaaldrich.com)
  • The carcinogenic to humans (group 1) in factors such as dietary choices and ex- findings were compared with similar the IARC monographs programme posure to tobacco smoke. (who.int)
  • A bioassay for the possible carcinogenicity of N-(1-naphthyl)ethylenediamine dihydrochloride was conducted using Fischer 344 rats and B6C3F1 mice. (nih.gov)
  • The present review summarizes, for the first time, synthesis, characterization, and application studies related to poly( 1 - Naphthylamine ) as well as its co polymer s, blends, and nanocomposites that have been carried out during the past two decades. (idexlab.com)
  • The decomposition of 1-naphthol in aqueous solutions on exposure to gamma radiation has been studied. (sigmaaldrich.com)
  • RÉSUMÉ Afin d'atteindre les objectifs de santé fixés par le pays pour 2011-2016, une analyse qualitative de l'exposition aux facteurs de risque de cancer au Qatar a été conduite en 2013. (who.int)
  • General procedure: A sealed tube equipped with a magnetic stirring bar was charged with styrene 1 (1.0mmol), NBS (2.0 mmol) and water (2.0mL) at room temperature. (ambeed.com)
  • General procedure: A solution of the proper olefin substrates (0.5 mmol), dimethylamine-borane (0.25 mmol) and 1 molpercent of the rhenium complex (with 10-15 molpercent of tBuOK according to Table 3) in the given solvent (0.8e1.0 ml) was stirred for given time at 70 °C under nitrogen atmosphere. (ambeed.com)
  • N-(1-Naphthyl)ethylenediamine dihydrochloride was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species. (nih.gov)
  • The high and low dietary concentrations of N-(1-naphthyl)ethylenediamine dihydrochloride administered to rats and male mice were 0.1 and 0.05 percent, respectively. (nih.gov)
  • There were no significant positive associations between the concentrations of N-(1-naphthyl)ethylenediamine dihydrochloride administered and mortality in rats of either sex or in male mice. (nih.gov)
  • Under the conditions of this bioassay, dietary administration of N-(1-naphthyl)ethylenediamine dihydrochloride was not carcinogenic in Fischer 344 rats or B6C3F1 mice. (nih.gov)
  • However, with an adeq battery of necf expsre blmarkers, prospective studies of en- vironmental effects on pregnancy outcomes might be possible. (cdc.gov)
  • 1-Naphthylamine is an aromatic amine derived from naphthalene. (wikipedia.org)
  • 1. The Secretariat has prepared the present scenario note for the first meeting of the Chemical Review Committee to assist participants in their preparations. (pic.int)
  • 1. In accordance with article 18 of the Convention, the Conference of the Parties, at its first meeting, established a subsidiary body, the Chemical Review Committee. (pic.int)
  • 1. The following results of the first meeting of the Conference of the Parties are relevant to the first meeting of the Chemical Review Committee. (pic.int)
  • 1. At its first meeting, the interim Chemical Review Committee developed a flow chart of the process and explanatory notes for drafting decision guidance documents for banned and severely restricted chemicals and severely hazardous pesticide formulations (UNEP/FAO/PIC/ICRC.1/6, annex IV). (pic.int)
  • 1. A working paper on preparing decision guidance documents for banned or severely restricted chemicals, originally developed by the interim Chemical Review Committee at its third session, was used by intersessional drafting groups in preparing decision guidance documents for chemicals that were considered at the Committee's fourth and fifth sessions. (pic.int)
  • 1. At its second session, the interim Chemical Review Committee agreed that, when forwarding notifications for review, the secretariat should initiate collection of information on international trade in the chemical concerned (UNEP/FAO/PIC/ICRC.2/11, para. (pic.int)
  • The obtained 1 H NMR data of the alkanes were identical to those of the literature [35,49-55]. (ambeed.com)
  • It undergoes hydrogenation in the presence of a rhodium catalyst to form cis , cis 1-decalol. (sigmaaldrich.com)
  • Journal of Ravishankar University (Part-B: Science), 28(1), pp. 1-10. (jru-b.com)
  • Journal of Ravishankar University (Part-B: Science),28(1), pp. 35-41. (jru-b.com)
  • Journal of Ravishankar University (Part-B: Science), 28(1), pp. 42-50. (jru-b.com)
  • Journal of Ravishankar University (Part-B: Science), 28(1), pp. 51-59. (jru-b.com)
  • PSERENADE TEAM, KRIZOVA, P. Changes in invasive pneumococcal disease caused by Streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE Project. (szu.cz)
  • Introduction The research of Hatch (1) has greatly increased our understand- ing of the use and potential limitations of biological markers for adverse reproductive effects. (cdc.gov)
  • The ability of biochar of orange peels in adsorbing 1-naphthol from water has been investigated. (sigmaaldrich.com)
  • As-synthesized rGO was dispersed in DI water containing 1, 2, 3, 4, and 5 wt% polyethylene glycol (PEG) to prepare PEG-rGO supramolecular assemblies. (bvsalud.org)