Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.
Substances and drugs that lower the SURFACE TENSION of the mucoid layer lining the PULMONARY ALVEOLI.
Layers of lipid molecules which are two molecules thick. Bilayer systems are frequently studied as models of biological membranes.
Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.
Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.
The characteristic three-dimensional shape of a molecule.
Protein-lipid combinations abundant in brain tissue, but also present in a wide variety of animal and plant tissues. In contrast to lipoproteins, they are insoluble in water, but soluble in a chloroform-methanol mixture. The protein moiety has a high content of hydrophobic amino acids. The associated lipids consist of a mixture of GLYCEROPHOSPHATES; CEREBROSIDES; and SULFOGLYCOSPHINGOLIPIDS; while lipoproteins contain PHOSPHOLIPIDS; CHOLESTEROL; and TRIGLYCERIDES.
The motion of phospholipid molecules within the lipid bilayer, dependent on the classes of phospholipids present, their fatty acid composition and degree of unsaturation of the acyl chains, the cholesterol concentration, and temperature.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a choline moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and choline and 2 moles of fatty acids.
A change of a substance from one form or state to another.
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
A nitrogen-free class of lipids present in animal and particularly plant tissues and composed of one mole of glycerol and 1 or 2 moles of phosphatidic acid. Members of this group differ from one another in the nature of the fatty acids released on hydrolysis.
Proteins found in the LUNG that act as PULMONARY SURFACTANTS.
Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.
The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes.
The physical characteristics and processes of biological systems.
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
A fluorescent compound that emits light only in specific configurations in certain lipid media. It is used as a tool in the study of membrane lipids.
A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)
Characteristics or attributes of the outer boundaries of objects, including molecules.
The mixture of gases present in the earth's atmosphere consisting of oxygen, nitrogen, carbon dioxide, and small amounts of other gases.
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The force acting on the surface of a liquid, tending to minimize the area of the surface. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
An anionic compound that is used as a reagent for determination of potassium, ammonium, rubidium, and cesium ions. It also uncouples oxidative phosphorylation and forms complexes with biological materials, and is used in biological assays.
Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has cytolytic properties, causes contracture of muscle, releases histamine, and disrupts surface tension, probably due to lysis of cell and mitochondrial membranes.
Materials in intermediate state between solid and liquid.
A pulmonary surfactant associated-protein that plays an essential role in alveolar stability by lowering the surface tension at the air-liquid interface. Inherited deficiency of pulmonary surfactant-associated protein B is one cause of RESPIRATORY DISTRESS SYNDROME, NEWBORN.
Lipids, predominantly phospholipids, cholesterol and small amounts of glycolipids found in membranes including cellular and intracellular membranes. These lipids may be arranged in bilayers in the membranes with integral proteins between the layers and peripheral proteins attached to the outside. Membrane lipids are required for active transport, several enzymatic activities and membrane formation.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to an ethanolamine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and ethanolamine and 2 moles of fatty acids.
Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.
A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.
The measurement of the quantity of heat involved in various processes, such as chemical reactions, changes of state, and formations of solutions, or in the determination of the heat capacities of substances. The fundamental unit of measurement is the joule or the calorie (4.184 joules). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.
A type of scanning probe microscopy in which a probe systematically rides across the surface of a sample being scanned in a raster pattern. The vertical position is recorded as a spring attached to the probe rises and falls in response to peaks and valleys on the surface. These deflections produce a topographic map of the sample.
A class of sphingolipids found largely in the brain and other nervous tissue. They contain phosphocholine or phosphoethanolamine as their polar head group so therefore are the only sphingolipids classified as PHOSPHOLIPIDS.
Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Deuterium. The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.
Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)
A naphthalene derivative with carcinogenic action.
The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.
Phospholipases that hydrolyze the acyl group attached to the 2-position of PHOSPHOGLYCERIDES.
The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a serine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and serine and 2 moles of fatty acids.
Phospholipids which have an alcohol moiety in ethereal linkage with a saturated or unsaturated aliphatic alcohol. They are usually derivatives of phosphoglycerols or phosphatidates. The other two alcohol groups of the glycerol backbone are usually in ester linkage. These compounds are widely distributed in animal tissues.
Measurement of the polarization of fluorescent light from solutions or microscopic specimens. It is used to provide information concerning molecular size, shape, and conformation, molecular anisotropy, electronic energy transfer, molecular interaction, including dye and coenzyme binding, and the antigen-antibody reaction.
A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Measurement of the intensity and quality of fluorescence.
Salts and esters of the 12-carbon saturated monocarboxylic acid--lauric acid.
The rate dynamics in chemical or physical systems.
Computer-based representation of physical systems and phenomena such as chemical processes.
A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN.
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Phospholipases that hydrolyze one of the acyl groups of phosphoglycerides or glycerophosphatidates.
The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Thin layers of tissue which cover parts of the body, separate adjacent cavities, or connect adjacent structures.
The accumulation of an electric charge on a object
Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.
A technique applicable to the wide variety of substances which exhibit paramagnetism because of the magnetic moments of unpaired electrons. The spectra are useful for detection and identification, for determination of electron structure, for study of interactions between molecules, and for measurement of nuclear spins and moments. (From McGraw-Hill Encyclopedia of Science and Technology, 7th edition) Electron nuclear double resonance (ENDOR) spectroscopy is a variant of the technique which can give enhanced resolution. Electron spin resonance analysis can now be used in vivo, including imaging applications such as MAGNETIC RESONANCE IMAGING.
The physical phenomena describing the structure and properties of atoms and molecules, and their reaction and interaction processes.
The study of CHEMICAL PHENOMENA and processes in terms of the underlying PHYSICAL PHENOMENA and processes.
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Physical motion, i.e., a change in position of a body or subject as a result of an external force. It is distinguished from MOVEMENT, a process resulting from biological activity.
Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.
Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.
Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.
Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Detergent-insoluble CELL MEMBRANE components. They are enriched in SPHINGOLIPIDS and CHOLESTEROL and clustered with glycosyl-phosphatidylinositol (GPI)-anchored proteins.
Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds.
A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Relating to the size of solids.
Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
... contains the peptide sinapultide (KL4 acetate, KLLLLKLLLLKLLLLKLLLLK), dipalmitoylphosphatidylcholine, 1-palmitoyl- ... 2-oleoyl-sn-glycero-3-phosphoglycerol (as the sodium salt), and palmitic acid.[citation needed] The scientific groundwork for ...
25-hydroxyvitamin d 2 MeSH D10.570.938.590 - lanosterol MeSH D10.627.430.354 - cod liver oil MeSH D10.627.430.450 - fatty acids ... 1-butanol MeSH D10.289.110.220 - chlorobutanol MeSH D10.289.110.855 - tert-butyl alcohol MeSH D10.289.220.720 - sodium dodecyl ... 1,2-dipalmitoylphosphatidylcholine MeSH D10.570.755.375.760.400.840 - phosphatidylethanolamines MeSH D10.570.755.375.760.400. ... sulfate MeSH D10.289.230.250 - dolichol phosphates MeSH D10.289.600.610 - 1-octanol MeSH D10.351.801.632 - triacetin MeSH ...
The SNALPs (around 81 nm in size here) were formulated by spontaneous vesiculation from a mixture of cholesterol, dipalmitoyl phosphatidylcholine ... Further, only 2 of the 6 mice treated had noticeable tumors around the implantation site. Even so, GAPDH, a tumor-derived ... Researchers tested a 1 mg/kg single dose, too, obtaining a 68% silencing of the target gene, indicating dose-dependent ... According to the study, a 2 mg/kg dose of PLK1-specific siRNA administered for 3 weeks to mice implanted with tumors resulted ...
... investigated as potential amphiphilic species for aiding adsorption of the pulmonary surfactant dipalmitoylphosphatidylcholine ... 1-Pentadecanol is an organic chemical compound classified as an alcohol. At room temperature, it is a white, flaky solid. It is ... Small amounts of 1-pentadecanol have been found (using thin-layer chromatography and GC/MS) to naturally occur in the leaves of ... It, along with 1-hexadecanol, was found to be selectively antimicrobial against P. acnes and not other Gram-positive bacteria ( ...
... and dipalmitoyl phosphatidylcholine. MPL is a derivative of the lipid A molecule found in the membrane of Gram-negative ... 2 (Supplement 4): S199-201. doi:10.1097/01.JTO.0000282977.65747.30. Merck KGaA to test Stimuvax in breast cancer trial ( ... The 26th modified amino acid, K, is palmityl-lysine (N6-(1-oxohexadecyl)-L-lysine), and the 27th is glycine. In the ... The first 25 amino acids of tecemotide are derived from the mucin 1 (MUC1, carcinoma-associated mucin, episialin, or CD227) ...
... (DPPC) is a phospholipid (and a lecithin) consisting of two C16 palmitic acid groups attached to ... Dipalmitoylphosphatidylcholine (DPPC) is routinely used to formulate some medicines used for treatment of respiratory distress ... "Dipalmitoylphosphatidylcholine - an overview , ScienceDirect Topics". www.sciencedirect.com. Retrieved 2019-10-25. Wang, Min; ... is dipalmitoylphosphatidylcholine or DPPC. While DPPC itself already has the ability to reduce the surface tension of the ...
40% dipalmitoylphosphatidylcholine (DPPC); ~40% other phospholipids (PC); ~10% surfactant proteins (SP-A, SP-B, SP-C and SP-D ... Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid with two 16-carbon saturated chains and a phosphate group with ... Up to 90% of surfactant DPPC (dipalmitoylphosphatidylcholine) is recycled from the alveolar space back into the type II ... dipalmitoylphosphatidylcholine (DPPC), reduces surface tension. As a medication, pulmonary surfactant is on the WHO Model List ...
The first trials of a potential treatment for HMD, dipalmitoylphosphatidylcholine, were published within a few years but were ... p. 1. Clarke, Thurston (July 1, 2013). "How "Icebergs" John F. and Jackie Kennedy Warmed to One Another After the Death of ... The infant's birth weight was 4 pounds 10+12 ounces (2.11 kg). He was the first baby to be born to a serving US president and ... 101 (1): 8-12. doi:10.1159/000325162. PMID 21791934. President John F. Kennedy on the Death of His Infant Son Patrick Bouvier ...
Hollars CW, Dunn RC (July 1998). "Submicron structure in L-alpha-dipalmitoylphosphatidylcholine monolayers and bilayers probed ... doi:10.1007/978-1-62703-782-2_7. ISBN 978-1-62703-781-5. PMID 24395412. Roos C, Kai L, Proverbio D, Ghoshdastider U, Filipek S ... 1666 (1-2): 105-17. doi:10.1016/j.bbamem.2004.04.011. PMID 15519311. Cavagnero S, Dyson HJ, Wright PE (April 1999). "Improved ... 75 (1): 342-53. Bibcode:1998BpJ....75..342H. doi:10.1016/s0006-3495(98)77518-6. PMC 1299703. PMID 9649391. Groves JT, Ulman N, ...
DPPC (dipalmitoylphosphatidylcholine), as mentioned above, is a lipid with very useful stabilizing and compacting attributes. ... The lipid shown to be most needed on this surface (Dipalmitoylphosphatidylcholine) does not easily move to the gas/fluid ... 17 (2): 407-29. doi:10.2741/3935. PMC 3635489. PMID 22201752. Lyra PP, Diniz EM, Abe-Sandes K, Angelo AL, Machado TM, Cardeal M ... 27 (1): 24-9. doi:10.2500/ajra.2013.27.3838. PMID 23406594. S2CID 34564655. Sarker M, Rose J, McDonald M, Morrow MR, Booth V ( ...
... and pulmonary surfactants such as dipalmitoylphosphatidylcholine. Lauramidopropyl betaine is the major component of ... In the first stage, a proton is transferred from the carboxyl group to a water molecule: H 2 N ( R ) CO 2 H + H 2 O ↽ − − ⇀ H 2 ... ISBN 978-1-285-60719-1.{{cite book}}: CS1 maint: numeric names: authors list (link) Jensen, Jan H.; Gordon, Mark S. (1995). "On ... It is generally assumed that K > 1, that is, that the zwitterion is the predominant amino acid isomer in aqueous solution. It ...
... from the content of phosphorus and contains 55 mg of phosphatidylcholine of which 30 mg is dipalmitoylphosphatidylcholine. ... Each milliliter of poractant alfa contains 80 mg of surfactant (extract) that includes 76 mg of phospholipids and 1 mg of ... and that infants treated at birth had similar neurodevelopmental status to untreated controls at a corrected age of 2 years. ...
Dipalmitoyl phosphatidylcholine (a.k.a. lecithin) is a major component of pulmonary surfactant and is often used in the L/S ... Animal lung phosphatidylcholine, for example, contains a high proportion of dipalmitoylphosphatidylcholine. Phospholipase D ... 4 (2): 135-7. doi:10.4103/0974-2077.85040. PMC 3183720. PMID 21976907. Kokkinidis DG, Bosdelekidou EE, Iliopoulou SM, Tassos AG ... Phosphatidylcholines at the US National Library of Medicine Medical Subject Headings (MeSH) [1] (CS1 maint: location, Articles ...
Dipalmitoyl phosphatidylcholine (DPPC), tripalmitin, SP-B , 0.5%, SP-C 99% of TP wt/wt ... Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. N Engl J Med. 2007. 357:1179-89. [QxMD MEDLINE Link ... Outcome at 2 years of age of infants from the DART study: a multicenter, international, randomized, controlled trial of low- ... Using a mask or nasal prongs, continuous positive airway pressure (CPAP) of at least 6 cm H2O should be used to stabilize ...
The surfactant has phospholipid dipalmitoyl phosphatidylcholine, which prevents lung collapse by reducing the surface tension ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. The ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. ... 2] Timely medical intervention with fiberoptic bronchoscopy with bronchoalveolar lavage in patients, particularly children, ...
Dipalmitoyl phosphatidylcholine (DPPC), or lecithin, is functionally the principle phospholipid. Phosphatidylglycerol makes up ... Dipalmitoyl phosphatidylcholine (DPPC), tripalmitin, SP-B , 0.5%, SP-C 99% of TP wt/wt ... Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. N Engl J Med. 2007. 357:1179-89. [QxMD MEDLINE Link ... Treat PDA with ibuprofen or indomethacin, which can be repeated during the first 2 weeks if the PDA reopens. [8] In refractory ...
Dipalmitoyl phosphatidylcholine (DPPC), tripalmitin, SP-B , 0.5%, SP-C 99% of TP wt/wt ... Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. N Engl J Med. 2007. 357:1179-89. [QxMD MEDLINE Link ... Outcome at 2 years of age of infants from the DART study: a multicenter, international, randomized, controlled trial of low- ... Transcutaneous CO2 monitors should be used in infants with ongoing respiratory distress to monitor ventilation if it correlates ...
The quality of case-associated BAL specimens was assessed by measuring dipalmitoylphosphatidylcholine (DPPC), the principal ... Benjamin C. Blount, PhD1,*; Mateusz P. Karwowski, MD1,*; Maria Morel-Espinosa, PhD1; Jon Rees, PhD1; Connie Sosnoff, MA1; ... 1Division of Laboratory Sciences, National Center for Environmental Health, CDC; 2Office of the Director, National Center for ... PhD1; Cliff Watson, PhD1; Tiffany Seyler, PhD1; Baoyun Xia, PhD1; David Chambers, PhD1; Peter Briss, MD2; Brian A. King, PhD3; ...
The surfactant has phospholipid dipalmitoyl phosphatidylcholine, which prevents lung collapse by reducing the surface tension ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. The ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. ... 2] Timely medical intervention with fiberoptic bronchoscopy with bronchoalveolar lavage in patients, particularly children, ...
... and PBS containing dipalmitoyl phosphatidylcholine (DPPC) and/or mouse serum albumin. To assess and compare how these various ... Advanced Search Search Help About NIOSHTIC-2 Feedback Terms: 'ultrafine*' OR ('nano*' AND 'particle*') OR 'nanotech*' OR ' ... NIOSHTIC-2 Publications Search. Search Results. New Search. ...
The surfactant has phospholipid dipalmitoyl phosphatidylcholine, which prevents lung collapse by reducing the surface tension ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. The ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. ... 2] Timely medical intervention with fiberoptic bronchoscopy with bronchoalveolar lavage in patients, particularly children, ...
R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol. (R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3- ... 1,2-Dimethylhydrazine. 1,2-Dimethylhydrazine (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details. ... 1,4-alpha-Glucan Branching Enzyme (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details. ... 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details ...
... and dipalmitoyl phosphatidylcholine (DPPC). To assess and compare how the various suspension medias dispersed the particles, ... Advanced Search Search Help About NIOSHTIC-2 Feedback Terms: 'ultrafine*' OR ('nano*' AND 'particle*') OR 'nanotech*' OR ' ... NIOSHTIC-2 Publications Search. Search Results. New Search. ...
Dipalmitoylphosphatidylcholine measurement (procedure) {104644005 , SNOMED-CT } Lecithin phosphorus measurement (procedure) { ...
Dipalmitoyl phosphatidylcholine (DPPC), or lecithin, is functionally the principle phospholipid. Phosphatidylglycerol makes up ... Dipalmitoyl phosphatidylcholine (DPPC), tripalmitin, SP-B , 0.5%, SP-C 99% of TP wt/wt ... Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. N Engl J Med. 2007. 357:1179-89. [QxMD MEDLINE Link ... Treat PDA with ibuprofen or indomethacin, which can be repeated during the first 2 weeks if the PDA reopens. [8] In refractory ...
Dipalmitoyl phosphatidylcholine (DPPC), tripalmitin, SP-B , 0.5%, SP-C 99% of TP wt/wt ... Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. N Engl J Med. 2007. 357:1179-89. [QxMD MEDLINE Link ... Outcome at 2 years of age of infants from the DART study: a multicenter, international, randomized, controlled trial of low- ... Table 2. Surfactant Preparations: Type, Source, Composition, Dosages, and Other Information. *Table 3. Results of a Meta- ...
... and PBS containing dipalmitoyl phosphatidylcholine (DPPC) and/or mouse serum albumin. To assess and compare how these various ...
R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol. (R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3- ... 1,2-Dimethylhydrazine. 1,2-Dimethylhydrazine (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details. ... 1,4-alpha-Glucan Branching Enzyme (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details. ... 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details ...
Surface activity of a synthetic lung surfactant containing a phospholipase-resistant phosphonolipid analog of dipalmitoyl phosphatidylcholine ...
Taku Fukuzawa 1 , Junji Ishida, Akira Kato, Taro Ichinose, Donna Maretta Ariestanti, Tomoya Takahashi, Kunitoshi Ito, Jumpei ...
... entry for 2ygp.1. WIF domain-EGF-like domain 1 Met77Trp of human Wnt inhibitory factor 1 in complex with 1,2- ... dipalmitoylphosphatidylcholine ... 2 x CA: CALCIUM ION(Non-covalent). CA.3: 4 residues within 4Å:* ... 2 x SPD: SPERMIDINE(Non-covalent). SPD.4: 8 residues within 4Å:*. Chain A: M.32, T.36, H.37, F.39, K.135, T.136, P.137, Q.138 ... 2 x PCF: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE(Non-covalent). PCF.1: 23 residues within 4Å:*. Chain A: L.7, I.9, L.17, I.18, I. ...
Lucinactant contains the peptide sinapultide (KL4 acetate, KLLLLKLLLLKLLLLKLLLLK), dipalmitoylphosphatidylcholine, 1-palmitoyl- ... 2-oleoyl-sn-glycero-3-phosphoglycerol (as the sodium salt), and palmitic acid.[citation needed] The scientific groundwork for ...
Possible changes in surface properties of 1,2-dipalmitoyl- phosphatidylcholine (DPL) and lung surfactant induced by kaolin ( ...
Yu, R. K., Itoh, T., Yohe, H. C. & Macala, L. J., Sep 19 1983, In: Brain Research. 275, 1, p. 47-52 6 p.. Research output: ... Xia, T., Gao, L., Yu, R. K. & Zeng, G., May 8 2003, In: Gene. 309, 2, p. 117-123 7 p.. Research output: Contribution to journal ... Zhang, Q., Schwade, M., Schafer, P., Weintraub, N. & Young, L., Apr 2020, In: Cardiology Research. 11, 2, p. 97-105 9 p.. ... Padilla, J., Harris, R. A., Rink, L. D. & Wallace, J. P., 2008, In: Vascular Medicine. 13, 2, p. 105-111 7 p.. Research output ...
Results: Dipalmitoyl phosphatidylcholine values in lung were 0.22 ± 0.27 μg/mg of total protein in preterm versus 1.96 ± 0.57 ... Results: Dipalmitoyl phosphatidylcholine values in lung were 0.22 ± 0.27 μg/mg of total protein in preterm versus 1.96 ± 0.57 ... Results: Dipalmitoyl phosphatidylcholine values in lung were 0.22 ± 0.27 μg/mg of total protein in preterm versus 1.96 ± 0.57 ... Results: Dipalmitoyl phosphatidylcholine values in lung were 0.22 ± 0.27 μg/mg of total protein in preterm versus 1.96 ± 0.57 ...
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Osteogenic effect of local, long versus short term BMP-2 delivery from a novel SPU-PLGA-βTCP concentric system in a critical ... Material-related effects of BMP-2 delivery systems on bone regeneration Acta Biomaterialia, Vol. 8, Núm. 2, pp. 781-791 ... Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: The effect of 1,2- ... dipalmitoylphosphatidylcholine Journal of Controlled Release, Vol. 51, Núm. 2-3, pp. 143-152 ...
Choi, K. M., Kim, K., Kwon, I. C., Kim, I. S. & Ahn, H. J., 2013 Jan 7, In: Molecular Pharmaceutics. 10, 1, p. 18-25 8 p.. ... Kim, M. S., Kim, S. K., Lee, J. Y., Cho, S. H., Lee, K. H., Kim, J. & Lee, S. S., 2008 Feb, In: Macromolecular Research. 16, 2 ... Woo, J. U., Kweon, S. H., Im, M., Lee, W. H., Kang, C. Y. & Nahm, S., 2017 Dec 1, In: Ceramics International. 43, 17, p. 15089- ... Lee, S. S., Min, S. S., Ahn, T. O. & Jho, J. Y., 1997, In: Polymer (Korea). 21, 2, p. 208-214 7 p.. Research output: ...
In this research, we report the novel formation process of supported Dipalmitoylphosphatidylcholine (DPPC) bilayers evaporated ... Catolica de Chile, Santiago, Chile - 2Faculty of Chemistry and CIEN-UC, P. Univ. Catolica de Chile, Santiago, Chile - 3 ... Sebastian Molina1, Maria Jose Retamal2, Nicolas Moraga1, Hugo Zelada1, Marco A. Soto-Arriaza2, Tomas P. Corrales3, and •Ulrich ... 1Institute of Physics and CIEN-UC, P. Univ. ...
2 (2009): Apr-June * Himanshu Gupta, Anubhav Anand1, Rakesh Pundir, C S Pandian, Shubhini Saraf, Fabrication of cefuroxime- ... interleukin-2 at its glycosylation site. Biotechnology 1990;8:343-6. Harris JM, Martin NE, Modi M. Pegylation: A novel process ... and pulmonary safety of inhaled insulin during 2-years of outpatient therapy. Paper (A101) published in the American Diabetes ... glycemic control in patients with type 2 diabetes failing combination oral agents: A 3-month, randomized, comparative trial for ...
For comparison, similar measurements have been carried out on aqueous dispersions of diacyl reference lipid dipalmitoyl phosphatidylcholine ... For comparison, similar measurements have been carried out on aqueous dispersions of diacyl reference lipid dipalmitoyl phosphatidylcholine ... the tetraether P2 lipids mix well with dipalmitoyl phosphatidylcholine lipids and stabilize conventional bilayer membranes. The ... the tetraether P2 lipids mix well with dipalmitoyl phosphatidylcholine lipids and stabilize conventional bilayer membranes. The ...
doi: 10.1007/978-1-4939-1417-3_7. Kaur SD, Singh G, Singh G, Singhal K, Kant S, Bedi N. Cubosomes as a potential nanocarrier ... 2018;5(1):76-81. doi: 10.30574/ gscbps.2018.5.1.0089. Bender J, Ericson MB, Merclin N, Iani V, Rosen A, Engstrom S, Moan J. ... 2021;10(3):1-7. Yara EE, Mona KY. Challenge of cubosomes in advanced and targeting drug delivery systems. Int J Sci Eng Res. ... 2019;1(12):119-29. He H, Rahimi K, Zhong M, Mourran A, Luebke DR, Nulwala HB. Cubosomes from hierarchical self-assembly of poly ...
Li, J. B.; Zhao, J.; Wu, J.; Miller, R.: Interaction of human serum albumin with dipalmitoylphosphatidylcholine in spread ... Li, J. B.; Zhao, J.; Miller, R.: Morphology and thermodynamics of dipalmitoylphosphatidylcholine monolayers penetrated by β- ... Hochschulschrift - Doktorarbeit (1). 2000. Hochschulschrift - Doktorarbeit Zhao, J.: Protein penetration into 2 D aggregating. ...
... for the morphology of self-assembled structures of glycosphingolipids and their mixtures with dipalmitoylphosphatidylcholine. ... Ripps, H., Peachey, N. S., Xu, X., Nozell, S. E., Smith, S. B. & Liou, G. I., 2000, In: Visual Neuroscience. 17, 1, p. 97-105 9 ... Stacy, R., Eroglu, A., Fowler, A., Biggers, J. & Toner, M., Feb 2006, In: Cryobiology. 52, 1, p. 99-107 9 p.. Research output: ... Gibbons, D. L., Pricl, S., Kantarjian, H., Cortes, J. & Quintás-Cardama, A., Jan 15 2012, In: Cancer. 118, 2, p. 293-299 7 p.. ...
from 63-45-6 to 63-91-2 is provided by Chemical Index, Online Chemical CAS Database. ... L-alpha-Dipalmitoyl phosphatidylcholine C40H80NO8P. *. 63-90-1 ... 2-hydroxyethyl)-N4,N4,N4,N4-tetramethyl-b4,b4-dioxo- ...
... and dipalmitoylphosphatidylcholine, a popular model "raft lipid. The transbilayer distributions of the SPM analogs and SPM in ... and dipalmitoylphosphatidylcholine, a popular model "raft lipid. The transbilayer distributions of the SPM analogs and SPM in ... and dipalmitoylphosphatidylcholine, a popular model "raft lipid. The transbilayer distributions of the SPM analogs and SPM in ... and dipalmitoylphosphatidylcholine, a popular model {"}raft lipid. The transbilayer distributions of the SPM analogs and SPM ...
Keywords: Cartilage - metabolism, 1,2-Dipalmitoylphosphatidylcholine - metabolism, Cattle, Dialysis, Filtration, Membranes, ...
The quality of case-associated BAL specimens was assessed by measuring dipalmitoylphosphatidylcholine (DPPC), the principal ... Benjamin C. Blount, PhD1,*; Mateusz P. Karwowski, MD1,*; Maria Morel-Espinosa, PhD1; Jon Rees, PhD1; Connie Sosnoff, MA1; ... 1Division of Laboratory Sciences, National Center for Environmental Health, CDC; 2Office of the Director, National Center for ... PhD1; Cliff Watson, PhD1; Tiffany Seyler, PhD1; Baoyun Xia, PhD1; David Chambers, PhD1; Peter Briss, MD2; Brian A. King, PhD3; ...
Dipalmitoylphosphatidylcholine (DPPC), cholesterol and curcumin. Since the transfection efficiency is highly dependent on the ... Phone : +1 415-690-1011 E-mail: [email protected] Offshore. Clinics in Oncology SN Techno Space, 1-98/4/154, First Floor, Hi- ... 2004; 56(1): 95-115.. *Ohtsuki T, Miki S, Kobayashi S, Haraguchi T, Nakata E, Hirakawa K, et al. The molecular mechanism of ... 2011; 1(1): 23-30.. *Thomas M, Lu JJ, Ge Q, Zhang C, Chen J, Klibanov AM. Full deacylation of polyethylenimine dramatically ...
... recently reported laser-triggered release of photosensitive compounds from liposomes containing dipalmitoylphosphatidylcholine ... In this study we have encapsulated the red light activatable anticancer photodynamic therapy drug 2-(1-Hexyloxyethyl)-2-devinyl ... DPPC) and 1,2 bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC). We hypothesized that the permeation of ...
The Tribological Character of LB Films of Dipalmitoylphosphatidylcholine (DPPC) International Conference on Mechanical and ...
Tonks A, Morris RH, Price AJ, Thomas AW, Jones KP & Jackson SK (2001) Dipalmitoylphosphatidylcholine modulates inflammatory ... 2003) Regulation of platelet-activating factor synthesis in human monocytes by dipalmitoyl phosphatidylcholine J Leukoc Biol ... in monocytic cells is inhibited by dipalmitoyl phosphatidylcholine via inhibition of enzymes of the remodelling pathway BLOOD ... 1) Evans M, Anderson RA, Graham J, Ellis GR, Morris K, Davies S, Jackson SK, Lewis MJ, Frenneaux MP & Rees A (2000) ...
... in hydrated dipalmitoylphosphatidylcholine. A time-resolved x-ray diffraction study using microwave-induced temperature-jumps ... serotonin receptor bound to an inverse agonist, Cell Discovery, 4, (1), 2018, p12- Journal Article, 2018 DOI TARA - Full Text ... A Host Lipid Screen, CRYSTAL GROWTH & DESIGN, 11, (2), 2011, p530-537 Journal Article, 2011 TARA - Full Text DOI ... Raman, P., Cherezov, V., Caffrey, M., The Membrane Protein Data Bank., Cellular and Molecular Life Sciences, 63, (1), 2006, p36 ...
The surfactant has phospholipid dipalmitoyl phosphatidylcholine, which prevents lung collapse by reducing the surface tension ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. The ... 1] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. ... 2] Timely medical intervention with fiberoptic bronchoscopy with bronchoalveolar lavage in patients, particularly children, ...
  • In this research, we report the novel formation process of supported Dipalmitoylphosphatidylcholine (DPPC) bilayers evaporated directly on bare silicon surfaces by means of physical vapor deposition, without the use of a polymer cushions or solvents, i.e. in a completely dry process. (dpg-verhandlungen.de)
  • The cationic polyplexes were encapsulated inside anionic liposomes formulated using 1,2-Dioleoyl-sn-glycero- 3-phosphoethanolamine (DOPE), Dipalmitoylphosphatidylcholine (DPPC), cholesterol and curcumin. (clinicsinoncology.com)
  • The quality of case-associated BAL specimens was assessed by measuring dipalmitoylphosphatidylcholine (DPPC), the principal phospholipid in naturally-occurring lung surfactant: the presence of acceptable levels of DPPC confirms that the lavage procedure recovered adequate pulmonary epithelial fluid. (cdc.gov)
  • We recently reported laser-triggered release of photosensitive compounds from liposomes containing dipalmitoylphosphatidylcholine (DPPC) and 1,2 bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC). (altmetric.com)
  • 9012} Its PLA2 activity is calcium-independent, functions optimally in acidic (pH = 4) conditions, and facilitates the intracellular processing of surfactant lipids, including dipalmitoylphosphatidylcholine (DPPC). (bertin-bioreagent.com)
  • For exposures 1 - 4 dipalmitoylphosphatidylcholine (DPPC) membranes in the liquid- condensed (LC) phase with an average superficial pressure of 28.5-32 mN/m were used. (emf-portal.org)
  • By adsorbing to the air-water interface of alveoli with the hydrophilic head groups in the water and the hydrophobic tails facing towards the air, the main lipid component of surfactant, dipalmitoylphosphatidylcholine (DPPC), reduces surface tension . (en-academic.com)
  • The interaction of Ca2+, with dipalmitoyl phosphatidylcholine (DPPC) model membranes was studied in the presence and absence of vitamin D-2 by using Fourier transform infrared spectroscopy. (metu.edu.tr)
  • Addition of vitamin D-2 and/or Ca2+ into pure DPPC liposomes shifts the phase transition to higher temperature, orders and decreases the dynamics of the acyl chains in both phases and does not induce hydrogen bond formation in the interfacial region. (metu.edu.tr)
  • 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) was used to represent a naturally occurring phospholipid. (datapdf.com)
  • I will be working on molecular dynamics simulations of Dipalmitoylphosphatidylcholine (DPPC), which is a key component of pulmonary surfactant. (northeastern.edu)
  • The decrease of the molecular mobility was observed from 1 mM Ca 2+ , at which the number of bound Ca 2+ is much less than that of the total lipid molecules. (elsevier.com)
  • Figure 2: Graphene nanosheet insertion and lipid extraction. (nature.com)
  • Molecular insight for the effect of lipid bilayer environments on thrombospondin-1 and calreticulin interactions. (uab.edu)
  • Impact of A2T and D23N Mutations on Tetrameric Aβ42 Barrel within a Dipalmitoylphosphatidylcholine Lipid Bilayer Membrane by Replica Exchange Molecular Dynamics. (ibpc.fr)
  • Methods were developed for the preparation of supported bilayer lipid membranes (1), and it was discovered that dried thin films of phospholipids spontaneously hydrate to yield lipid vesicles (2). (pdfhall.com)
  • At a mole ratio of 1:2, the tetraether P2 lipids mix well with dipalmitoyl phosphatidylcholine lipids and stabilize conventional bilayer membranes. (unical.it)
  • Interaction between Ca2+ and dipalmitoylphosphatidylcholine membranes. (elsevier.com)
  • The effect of Ca 2+ on the molecular mobility in dipalmitoylphosphatidylcholine membranes was studied by steady-state and time-resolved measurements of fluorescence anisotropy. (elsevier.com)
  • In this study we have encapsulated the red light activatable anticancer photodynamic therapy drug 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH) (Ex/Em410/670 nm) together with calcein (Ex/Em490/517 nm) as a marker for drug release in Pocket liposomes. (altmetric.com)
  • Morphology and thermodynamics of dipalmitoylphosphatidylcholine monolayers penetrated by β-casein and β-lactoglobulin at the air/water interface. (mpg.de)
  • Interaction of human serum albumin with dipalmitoylphosphatidylcholine in spread monolayers at the air/water interface. (mpg.de)
  • The factors 2 arise from the contribution of the two monolayers of the bilayer. (pdfhall.com)
  • However, inclusion of 2 and 10 mol % dihydroSPM in SPM/ POPC ( 1: 1) vesicles mitigated and completely abrogated the effect of SPM on the transbilayer distribution of GalCer. (abo.fi)
  • In this study, the center-of-mass diffusion and shape fluctuations of large unilamellar 1-palmitoyl-2-oleyl-sn-glycero-phosphatidylcholine vesicles prepared by extrusion are studied by means of neutron spin echo in combination with dynamic light scattering. (uni-bielefeld.de)
  • The difference in skin interaction between occlusive and non-occlusive application is of importance for deformable vesicles 2 . (ijpsr.com)
  • When native GM1 (49.3% C18:1 and 50.7% C20:1 LCB, respectively), was inserted in dipalmitoylphosphatidylcholine vesicles and partially oxidized (10%), the proportion of C18:1 and C20:1 species in the oxidized GM1 was 59.6% and 40.4%, respectively, suggesting a preferential action of the enzyme on the shorter species. (unimib.it)
  • Analyses of THC-containing product samples by FDA and state public health laboratories have identified potentially harmful constituents in these products, such as vitamin E acetate, medium chain triglyceride oil (MCT oil), and other lipids ( 2 , 3 ) (personal communication, D.T. Heitkemper, FDA Forensic Chemistry Center, November 2019). (cdc.gov)
  • CUROSURF is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids) and 1% hydrophobic low molecular weight proteins (surfactant associated proteins SP-B and SP-C). (rxlist.com)
  • 1993. In vitro percutaneous absorption and metabolism in man of 2-chloro-4-ethylamino-6-isopropylamine-s-triazine (atrazine). (cdc.gov)
  • A dipalmitoylphosphatidylcholine is a phospholipid consisting of two palmitic acids, the major constituent of pulmonary surfactant. (lotsofwords.com)
  • Bottom left: the phospholipid 1-palmitoyl-2-oleoylphosphatidylcholine ('''POPC''') Center right: sodium bis(2-ethylhexyl)sulfosuccinate ('''AOT''') AOT is a rare surfactant - it is soluble and active in both oil and water. (harvard.edu)
  • The fluorescence anisotropy decay of 1,6-diphenyl-1,3,5-hexatriene in the hydrocarbon region indicated that the free volume of molecular rotation became more restricted when the Ca 2+ concentration was increased. (elsevier.com)
  • Figure 1: Morphology of E. coli exposed to graphene oxide nanosheets. (nature.com)
  • The weight percent of ZrO 2 in coatings and the surface morphology of coatings were examined. (asme.org)
  • Lucinactant contains the peptide sinapultide (KL4 acetate, KLLLLKLLLLKLLLLKLLLLK), dipalmitoylphosphatidylcholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol (as the sodium salt), and palmitic acid. (wikipedia.org)
  • Akademia Górniczo-Hutnicza, Kraków, Wydział Fizyki i Informatyki Stosowanej, umowa zawarta 1 listopada 2017 (dr Jacek Nizioł). (edu.pl)
  • [2] [5] In the United Kingdom a year of treatment costs the NHS about £196,000 as of 2021. (mdwiki.org)
  • Among the four surfactant apoproteins identified, surfactant protein B (SP-B) and SP-C are two small hydrophobic proteins that make up 2-4% of the surfactant mass and are present in commercially available surfactant preparations. (medscape.com)
  • The observed crystal packing of the domains provides a plausible model for the association of multiple tandemly linked EGF-like domains in proteins such as fibrillin-1, Notch, and protein S. This model is consistent with the known functional data and suggests a general biological role for these domains. (embl.de)
  • Effects of altered restraints in β1 integrin on the force-regulated interaction between the glycosylated I-like domain of β1 integrin and fibronectin III9-10: a steered molecular dynamic study. (uab.edu)
  • The bilayer is a two-dimensional fluid composed of amphiphiles with their hydrophilic head groups exposed to the aqueous solutions and their hydrophobic tails aggregated to exclude water (Fig. 1). (pdfhall.com)
  • Influence of tungsten disulfide particles (WS 2 ) on the friction and wear behavior of Mg-AZ91 forms the objective of this work. (asme.org)
  • Tribo-oxidation mechanism and tribological behavior of TaC-20 vol%SiC composites from 25 to 800 °C coupled with aluminum oxide (Al 2 O 3 ) and cemented carbide (WC-Co) were investigated. (asme.org)
  • The results show that ultrasonic agitation can greatly affect the microstructure and the tribological behavior of Ni-ZrO 2 nanocomposite coatings. (asme.org)
  • Therefore, the Ni-ZrO 2 nanocomposite coating by ultrasonic electrodeposition exhibits high microhardness and excellent tribological behavior. (asme.org)
  • [ 1 ] Atelectasis occurs when the alveoli (small air sacs) within the lung become deflated or fill with alveolar fluid. (medscape.com)
  • Ni-ZrO 2 nanocomposite coatings were fabricated by electrodeposition from a modified Watt's type electrolyte containing ZrO 2 nanoparticles, where an ultrasonic field was imposed during electrodeposition process. (asme.org)
  • The dispersed ZrO 2 nanoparticles in coatings and ultrasonic agitation during electrodeposition synthetically contribute to the grain refinement of the coatings. (asme.org)
  • In general, the improvement in friction and wear properties of Ni-ZrO 2 nanocomposite coatings can be attributed to the homogeneously dispersed ZrO 2 nanoparticles and the finer-grained structure. (asme.org)
  • Possible changes in surface properties of 1,2-dipalmitoyl- phosphatidylcholine (DPL) and lung surfactant induced by kaolin (1332587) dust were investigated using a Wilhelmy surface balance. (cdc.gov)
  • Each milliliter of suspension contains 80 mg of poractant alfa (surfactant extract) that includes 76 mg of phospholipids and 1 mg of protein of which 0.45 mg is SP-B and 0.59 mg is SP-C. The amount of phospholipids is calculated from the content of phosphorus and contains 55 mg of phosphatidylcholine of which 30 mg is dipalmitoylphosphatidylcholine. (rxlist.com)
  • With a risk rate 1 in 75 women getting ovarian cancer and a mortality rate of 1 in 100, conjugative tumour therapeutics involving gene therapy and photodynamic therapy offer a promising adjunct to the prevailing therapies. (clinicsinoncology.com)
  • 2019;1(12):119-29. (innovareacademics.in)
  • Based on data collected as of October 15, 2019, 86% of 867 EVALI patients reported using tetrahydrocannabinol (THC)-containing products in the 3 months preceding symptom onset ( 1 ). (cdc.gov)
  • Short stack design was based on electrochemical data obtained at 0.60 V was 0.45 A/cm(2) from performance tests. (metu.edu.tr)
  • Molecular and Structural Insight for the Role of Key Residues of Thrombospondin-1 and Calreticulin in Thrombospondin-1- Calreticulin Binding. (uab.edu)
  • The microstructure showed the grain refinement of FSP AZ91/WS 2 composite, due to severe plastic deformation and dynamic recrystallization. (asme.org)
  • The improvement in the hardness is due to the reinforcement of WS 2 and grain refinement. (asme.org)
  • Catolica de Chile, Santiago, Chile - 2 Faculty of Chemistry and CIEN-UC, P. Univ. (dpg-verhandlungen.de)
  • Stud Univ Babes-Bolyai, Biol 24(2):32-35. (cdc.gov)
  • Proc Soc Exp Biol Med 1957;95:170-2. (pneumon.org)
  • A summary of vesicle-forming block copolymers is given in Table 1. (pdfhall.com)
  • Friction stir processing (FSP) has been used to fabricate FSP AZ91/WS 2 composite with various FSP passes. (asme.org)
  • The hardness of FSP AZ91/WS 2 composite is increased to 122 HV, from 62.2 HV 0.3 of Mg-AZ91. (asme.org)
  • Role of Altered Sialylation of the I-like Domain of β1 Integrin in the Binding of Fibronectin to β1 Integrin: Thermodynamics and Conformational Analyses. (uab.edu)
  • Higher the microhardness of the (Al 2 O 3 + TiN)/Ti6Al4V clad layer in the cladding zone compared with other clad layer compositions such as Ti6Al4V, Al 2 O 3 /Ti6Al4V, and TiN/Ti6Al4V, it is varied from 1130HV 0.2 to 1222HV 0.2 , and the average microhardness is about 990.57HV 0.2 which is 175% improvement compared with the substrate. (asme.org)
  • The microhardness and tribological properties of Ni-ZrO 2 nanocomposite coatings and pure Ni coating were investigated. (asme.org)