A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Hydrazines substituted with two methyl groups in any position.
Hydrazines substituted by one or more methyl groups in any position.
Hydrazine substituted by one methyl group.
Tumors or cancer of the COLON.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Products of the hydrolysis of chlorophylls in which the phytic acid side chain has been removed and the carboxylic acids saponified.
The aglycone of CYCASIN. It acts as a potent carcinogen and neurotoxin and inhibits hepatic DNA, RNA, and protein synthesis.
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
The combination of two or more different factors in the production of cancer.
Tumors or cancer of the INTESTINES.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
A plant genus of the family ARACEAE. Members contain konjac glucomannan (MANNANS) and SEROTONIN.
A malignant neoplasm arising simultaneously or consecutively in mesodermal tissue and glandular epithelium of the same part. (Stedman, 25th ed)
A malignant epithelial tumor with a glandular organization.
Tumors or cancer of the CECUM.
A segment of the LOWER GASTROINTESTINAL TRACT that includes the CECUM; the COLON; and the RECTUM.
The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A benign epithelial tumor with a glandular organization.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.
High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.
A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.
A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.
The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
... symmetrical dimethylhydrazine) are hydrazines where two hydrogen atoms are replaced by methyl groups. UDMH is the easier of the ... 2] For the preparation of aliphatic hydrazines, the reaction of hydrazine with alkylating compounds such as alkyl halides is ... 2,4-dinitrophenylhydrazine (2,4-DNPH) is commonly used to test for ketones and aldehydes in organic and clinical chemistry. ... 1,1-Dimethylhydrazine is produced by the reduction of N-nitrosodimethylamine. The reduction of benzenediazonium chloride with ...
3.0.CO;2-E. PMID 9028353. S2CID 32446993. Di Marzio L, Di Leo A, Cinque B, Fanini D, Agnifili A, Berloco P, Linsalata M, ... 43 (2): 316-24. doi:10.1016/S0022-2275(20)30174-7. PMID 11861674. Duan RD, Cheng Y, Hansen G, Hertervig E, Liu JJ, Syk I, ... 235 (1): 141-6. doi:10.1016/j.canlet.2005.04.016. PMID 16290921. Soo I, Madsen KL, Tejpar Q, Sydora BC, Sherbaniuk R, Cinque B ... J. 394 (Pt 1): 299-308. doi:10.1042/BJ20051121. PMC 1386028. PMID 16255717. Andersson D, Kotarsky K, Wu J, Agace W, Duan RD ( ...
In a study where rats were treated with Brevetoxin B (PbTx2), there was a noticeable 2-3 fold growth in the amount of DNA seen ... 681 (2-3): 271-298. doi:10.1016/j.mrrev.2008.11.004. PMID 19103303. Wyrobek AJ, Schmid TE, Marchetti F (2005-03-01). "Relative ... 582 (1-2): 116-134. doi:10.1016/j.mrgentox.2005.01.005. PMID 15781217. Vanhauwaert A, Vanparys P, Kirsch-Volders M (January ... Additionally, 1,2-dimethylhydrazine is a known colon carcinogen and shows signs of possessing clastogenic activity. There are ...
The most common hypergolic fuels, hydrazine, monomethylhydrazine and unsymmetrical dimethylhydrazine, and oxidizer, nitrogen ... Unsymmetrical dimethylhydrazine (UDMH) + nitrogen tetroxide (NTO) - frequently used by Roscosmos, such as in the Proton (rocket ... and unsymmetrical dimethylhydrazine (UDMH). In 1935, Hellmuth Walter discovered that hydrazine hydrate was hypergolic with high ... Ariane 1 through 4, with their hypergolic first and second stages (and optional hypergolic boosters on the Ariane 3 and 4) have ...
"Anti-Oxidative Effect of Myrtenal in Prevention and Treatment of Colon Cancer Induced by 1, 2-Dimethyl Hydrazine (DMH) in ...
9 (2): 179-88. doi:10.1038/sj/cdd/4400935. PMID 11840168. Lan A, Bruneau A, Bensaada M, Philippe C, Bellaud P, Rabot S, Jan G ( ... 91 (1): 1-26. doi:10.1051/dst/2010032. S2CID 6044008. Jan G, Belzacq AS, Haouzi D, Rouault A, Métivier D, Kroemer G, Brenner C ... Cousin FJ, Mater DD, Foligne B, Jan G (2 August 2010). "Dairy propionibacteria as human probiotics: A review of recent evidence ... 1-29. doi:10.1002/9781118960608.gbm00167. ISBN 9781118960608. Frohnmeyer, Esther; Deptula, Paulina; Nyman, Tuula A.; Laine, Pia ...
2-Dimethylhydrazine. In 1986 James became a Diplomate of the American Board of Toxicology (DABT). James is the chief scientist ... thesis was entitled The DNA Adducts and Neoplastic Changes Produced in the Large Intestine of ICR/Ha and CSTBI/Ha Mice by 1, ...
132 (2): 656-66. doi:10.1021/ja907716f. PMID 20028024. Peng-Yu Y, Min W, Kai L, Mun Hong N, Omar S, JLear M, Siu Kwan S, ... 240 (2): 221-4. doi:10.1016/j.canlet.2005.09.011. PMID 16377080. Takayama T, Katsuki S, Takahashi Y, Ohi M, Nojiri S, Sakamaki ... Yang P, Wang M, Liu K, Ngai MH, Sheriff O, Lear MJ, Sze SK, He CY, Yao SQ (2 July 2012). "Parasite-based screening and proteome ... ISBN 978-1-56363-527-4. "Chemists to provide obesity pill". BBC News Online. 21 January 2009. Archived from the original on 23 ...
The molecular formula C2H8N2 (molar mass: 60.10 g/mol, exact mass: 60.0688 u) may refer to: Dimethylhydrazine Ethylenediamine, ... or ethane-1,2-diamine This set index page lists chemical structure articles associated with the same molecular formula. If an ...
Members of this class include: Monomethylhydrazine Dimethylhydrazines Symmetrical dimethylhydrazine (1,2-dimethylhydrazine) ... Trimethylhydrazine 1,1,2-trimethylhydrazine 1,1,1-trimethylhydrazinium (cationic and exists as a variety of salts e.g. 1,1,1- ... 1,1,2-tetramethylhydrazinium (cationic and exists as a variety of salts) Pentamethylhydrazinium (cationic and exists as a ...
Volumes 1-124". IARC Monographs on the Evaluation of Risk to Humans. IARC. July 7, 2019. Retrieved July 14, 2019. "IARC ... 3-cyclohexyl-1-nitrosourea) 4-Chloro-o-toluidine Chlorozotocin Cisplatin Cyclopenta[c,d]pyrene Diazinon Dibenz[a,j]acridine ... July 1, 2016). "Carcinogenicity of drinking coffee, mate, and very hot beverages". The Lancet Oncology. Elsevier. 17 (7): 877-8 ... 2,3-Trichloropropane Tris(2,3-dibromopropyl) phosphate Vinyl bromide Vinyl fluoride Malaria (caused by infection with ...
... dimethylhydrazines MeSH D02.442.600.400.200 - 1,2-dimethylhydrazine MeSH D02.442.600.601 - monomethylhydrazine MeSH D02.442. ... vitamin k 1 MeSH D02.455.849.291.523.500.844 - vitamin k 2 MeSH D02.455.849.291.523.500.922 - vitamin k 3 MeSH D02.455.849.291. ... 3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide MeSH D02.092.146.325 - p-dimethylaminoazobenzene MeSH D02.092. ... 5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole MeSH D02.640.600.290 - fanft MeSH D02.640.600.308 - furagin MeSH D02.640.600.313 - ...
Look up dimethylhydrazine in Wiktionary, the free dictionary. Dimethylhydrazine is the name of two compounds with the molecular ... These are: unsymmetrical dimethylhydrazine (1,1-dimethylhydrazine), with both methyl groups bonded to the same nitrogen atom ... symmetrical dimethylhydrazine (1,2-dimethylhydrazine), with one methyl group bonded to each of the two nitrogen atoms ...
... , or 1,2-Dimethylhydrazine, is the organic compound with the formula (CH3NH)2. It is one of the ... Symmetrical dimethylhydrazine is a potent carcinogen that acts as a DNA methylating agent. The compound has no commercial value ... Unsymmetrical dimethylhydrazine 74-79-3 1,2-Dimethylhydrazine 1,2-Dimethylhydrazine from PubChem Record of 1,2-Dimethylhydrazin ... two isomers of dimethylhydrazine. Both isomers are colorless liquids at room temperature, with properties similar to those of ...
Symmetrical dimethylhydrazine, 1,2-dimethylhydrazine is also known but is not as useful. UDMH is produced industrially by two ... Unsymmetrical dimethylhydrazine (UDMH; 1,1-dimethylhydrazine, НДМГ or codenamed Geptil) is a chemical compound with the formula ... "PERFORMANCE SPECIFICATION PROPELLANT, uns-DIMETHYLHYDRAZINE (MIL-PRF-25604F)". ASSIST Database Quicksearch. 2014-03-11. ... Retrieved 2 August 2016 - via ijbch.kaznu.kz. {{cite journal}}: Cite journal requires ,journal= (help) Encyclopedia ...
The Qiam 1's accuracy is also improved with the addition of a separable warhead. Other changes to the warhead include a "baby- ... Far simpler than the V-2's multi-chamber design, and employing an anti-oscillation baffle to prevent chugging, it was a ... with unsymmetrical dimethylhydrazine (UDMH, Russian TG-02 like German Tonka 250) as liquid igniter (self-ignition with IRFNA) ... The earlier R-1 missile had carried the NATO name SS-1 Scunner, but was of a very different design, almost directly a copy of ...
Unsymmetrical dimethylhydrazine (UDMH) or monomethylhydrazine (MMH) / dinitrogen tetroxide (NTO or N 2O 4) Used in three first ... hydrazine or unsymmetrical dimethylhydrazine (UDMH) as fuel were then adopted in the United States and the Soviet Union for use ... The V-2 rockets developed by Nazi Germany used LOX and ethyl alcohol. One of the main advantages of alcohol was its water ... 21,2, Feb. 1979): In a cabled exclusive to The New York Times on 30 September 1929, Fritz von Opel is quoted as saying: "Sander ...
The missile used a hypergolic bipropellant combination of unsymmetrical dimethylhydrazine (UDMH) fuel in combination with red ... ISBN 5-7111-0333-1 "Катастрофа на Байконуре: почему погибли 124 человека во главе с маршалом" (The disaster at Baikonur), ... Initial operational capability was achieved on 1 November 1961. The missile continued to serve until 1976, with maximum ... the first flight of the missile took place on 2 February 1961. ...
It uses the storable hypergolic propellants unsymmetrical dimethylhydrazine (UDMH) and dinitrogen tetroxide (N2O4), and can ... "YZ-1 space tug". B14643.DE. Archived from the original on August 25, 2015. Retrieved 2015-07-25. "长征七号首飞成功 空间实验室任务大幕拉开" [ ... Yuanzheng-2 (AKA YZ-2) (Chinese: 远征二号; pinyin: Yuǎn Zhēng Èr Hào; lit. 'Expedition Two'): New version used with the 5.2 m (17 ... Operational variants are designated YZ-1 for Long March 3B and 3C, YZ-1A for Long March 7, YZ-1S for Long March 2C,
Dimefox Dimethoate Dimethyl phosphorochloridothioate Dimethyl-p-phenylenediamine Dimethyldichlorosilane Dimethylhydrazine ... 2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester Phosphonothioic acid, methyl-, O-(4-nitrophenyl) O-phenyl ester Phosphoric acid ... July 1, 2008 ed.), Government Printing Office, archived from the original (PDF) on 2012-02-25, retrieved March 8, 2009 ( ... 2-chloroethyl)amine Valinomycin Vinyl acetate monomer Warfarin Warfarin sodium Xylylene dichloride Zinc phosphide List of ...
... is formed from the rocket fuel unsymmetrical dimethylhydrazine (UDMH) and methyl iodide, and acts as a vicarious nucleophilic ... TATB, triaminotrinitrobenzene or 2,4,6-triamino-1,3,5-trinitrobenzene is an aromatic explosive, based on the basic six-carbon ... TATB is produced by nitration of 1,3,5-trichlorobenzene to 1,3,5-trichloro-2,4,6-trinitrobenzene, then the chlorine atoms are ...
... and unsymmetrical dimethylhydrazine, (CH3)2NNH2, also known as UDMH (melting point −57 °C). These derivatives are used in two- ... For hydrazine the 1-hour SPEGL is 2 ppm, with a 24-hour SPEGL of 0.08 ppm. A complete surveillance programme for hydrazine ... 2 (6): 972-974. Bibcode:1965JSpRo...2..972H. doi:10.2514/3.28327. Vieira R, Pham-Huu C, Kellera N, et al. (2002). "New carbon ... Reaction 2 is the most exothermic, but produces a smaller number of molecules than that of reaction 1. Reaction 3 is ...
Attitude was controlled by a Sun-star sensor with attitude correction performed by a dimethylhydrazine/nitric acid bipropellant ... Mars 1M No.1, known in the West as Marsnik 1, Mars 1960A and Korabl 4, was destroyed in a launch failure on October 10, 1960. ... Mars 1M No.2, known in the West as Marsnik 2, Korabl 5 and Mars 1960B, was launched on October 14, 1960. Both Mars 1M ... Mars 1M No.2 reached an altitude of 120 km before reentry. Soviet premier Nikita Khrushchev had planned to bring models of the ...
Proton K is fuelled by very toxic unsymmetrical dimethyl hydrazine and nitrogen tetroxide. These are hypergolic fuels which ... During the Cold War, it was designated the D-1/D-1e or SL-12/SL-13 by Western intelligence agencies. Launch capacity to low ... On 2 July 2013, a Proton-M launching three GLONASS navigation satellites experienced a failure reminiscent of the 1960s ... 2 July 2013. "Commercial Launch Heritage , Proton Rocket , International Launch Services". ilslaunch.com. Retrieved 13 ...
a b c d e f g h i j Working with modern hydrocarbon and oxygenated solvents: a guide to flammability Archived June 1, 2009, at ... 1. ∑. i. x. i. L. F. L. i. {\displaystyle LFL_{\text{mix}}={\frac {1}{\sum _{i}{\frac {x_{i}}{LFL_{i}}}}}}. and similar for UFL ... "2-HEXANONE ICSC:0489". oit.org. Retrieved 18 March 2018.. *^ "IPCS INTOX Site Closed". www.intox.org. Retrieved 18 March 2018. ... Methane gas has an LFL of 4.4%.[1][2] If the atmosphere has less than 4.4% methane, an explosion cannot occur even if a source ...
Long March 1's 1st and 2nd stage used nitric acid and Unsymmetrical dimethylhydrazine (UDMH) propellants, and its upper stage ... The Long March 1 was quickly replaced by the Long March 2 family of launchers. Long March 1 Long March 1 engine After the U.S. ... Retrieved 1 March 2021. "China Aims for Humanity's Return to the Moon in the 2030s". popsci.com. 5 May 2016. Archived from the ... Jones, Andrew (1 October 2020). "China is building a new rocket to fly its astronauts on the Moon". SPACE.com. Jones, Andrew ( ...
... and unsymmetric dimethyl hydrazine (UDMH, (CH3)2N2H2) - Soviet Scud-C, aka SS-1-c,-d,-e Nitric acid 73% with dinitrogen ... MIM-3 Nike Ajax Antiaircraft Rocket Unsymmetric dimethylhydrazine (UDMH) and dinitrogen tetroxide (N2O4) - Proton, Rokot, Long ... 2. NASA. Mejía 2017, pp. 115-116. "El peruano que se convirtió en el padre de la astronáutica inspirado por Julio Verne y que ... Examples: Saturn V's F-1 and J-2, Delta IV's RS-68, Ariane 5's HM7B, Falcon 9's Merlin. Tap-off cycle Takes hot gases from the ...
Furfuryl alcohol - also hypergolic with nitric acid but lower performance Unsymmetrical dimethylhydrazine - a higher ... ISBN 0-8135-0725-1. Nodong missile analysis by FAS. data on R-13/SS-N-4 and R-21/SS-N-5 Isayev engine S5.38 Soviet/Russian ... p. 2. IAC-04-IAA-6.15.3.02. Archived from the original (PDF) on 2015-10-24. (Articles with short description, Short description ...
With the use of the newly developed Hydyne, composed of a blend of 60% unsymmetrical dimethylhydrazine (UDMH) and 40% ... Hydyne is a mixture of 60% unsymmetrical dimethylhydrazine (UDMH) and 40% diethylenetriamine (DETA), developed in 1957 at ... ISBN 1-56347-649-5. NASA. The Mercury-Redstone Project, p. 3-2, 4-42. History of the Redstone Missile System, p. 60 History of ... Hydyne was used as the fuel for the first stage of the Juno I rocket that launched Explorer 1, the first successful satellite ...
A-α-C (2-Amino-9H-pyrido[2,3-b]indole) Acetaldehyde Acetamide Acrylonitrile AF-2 (2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide) ... 2 Cobalt and cobalt compounds 1 Cobalt sulfate and other soluble cobalt(II) salts Coconut oil diethanolamine condensate para- ... "List of Classifications, Agents classified by the IARC Monographs, Volumes 1-124". IARC Monographs on the Evaluation of Risk to ... 1 Heptachlor Hexachlorobenzene Hexachloroethane Hexachlorocyclohexanes Hexamethylphosphoramide (HMPA) 2,4-Hexadienal Human ...

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