Mesylates: Organic salts or esters of methanesulfonic acid.Quaternary Ammonium Compounds: Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. These are distinguished from IMINES which are RN=CR2.Chlorides: Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.Ethyl Methanesulfonate: An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect.Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.Diphenylhexatriene: A fluorescent compound that emits light only in specific configurations in certain lipid media. It is used as a tool in the study of membrane lipids.Sulfhydryl Reagents: Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling.Chloride Channels: Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective blockers include FENAMATES; ETHACRYNIC ACID; and TAMOXIFEN.Cetrimonium Compounds: Cetyltrimethylammonium compounds that have cationic detergent, antiseptic, and disinfectant activities. They are used in pharmaceuticals, foods, and cosmetics as preservatives; on skin, mucous membranes, etc., as antiseptics or cleansers, and also as emulsifiers. These compounds are toxic when used orally due to neuromuscular blockade.Fatty Acids, Monounsaturated: Fatty acids which are unsaturated in only one position.Cations: Positively charged atoms, radicals or groups of atoms which travel to the cathode or negative pole during electrolysis.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Quinuclidinyl Benzilate: A high-affinity muscarinic antagonist commonly used as a tool in animal and tissue studies.Receptors, Muscarinic: One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology.Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.QuinuclidinesMuscarinic Antagonists: Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
... trimethylammonium chloride MeSH D02.455.426.100 --- bridged compounds MeSH D02.455.426.100.050 --- adamantane MeSH D02.455. ... m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride MeSH D02.092.877.674.333 --- edrophonium MeSH D02.092.877.674. ... trimethylammonium chloride MeSH D02.675.276.232 --- choline MeSH D02.675.276.232.100 --- benzoylcholine MeSH D02.675.276.232. ... methacholine chloride MeSH D02.675.276.558 --- bis-trimethylammonium compounds MeSH D02.675.276.558.372 --- decamethonium ...
... m-chlorophenylcarbamoyloxy)-2-butynyl trimethylammonium chloride] showed little Gpp(NH)p-induced shift in [3H]PZ-labeled ... trimethylammonium Chloride Medicine & Life Sciences View full fingerprint Cite this. * APA ... m-chlorophenylcarbamoyloxy)-2-butynyl trimethylammonium chloride] showed little Gpp(NH)p-induced shift in [3H]PZ-labeled ... m-chlorophenylcarbamoyloxy)-2-butynyl trimethylammonium chloride] showed little Gpp(NH)p-induced shift in [3H]PZ-labeled ...
... trimethylammonium chloride MeSH D02.455.426.100 --- bridged compounds MeSH D02.455.426.100.050 --- adamantane MeSH D02.455. ... m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride MeSH D02.092.877.674.333 --- edrophonium MeSH D02.092.877.674. ... trimethylammonium chloride MeSH D02.675.276.232 --- choline MeSH D02.675.276.232.100 --- benzoylcholine MeSH D02.675.276.232. ... methacholine chloride MeSH D02.675.276.558 --- bis-trimethylammonium compounds MeSH D02.675.276.558.372 --- decamethonium ...
... trimethylammonium Chloride. Code System Preferred Concept Name. (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ...
... trimethylammonium Chloride (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details. ... m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride. (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl) ... R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol. (R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3- ... 1,2-Dimethylhydrazine. 1,2-Dimethylhydrazine (Structural Class). NDF-RT (Drug Classification). Drug Classes (NDF-RT). Details. ...
Unfortunately 4-[N-(4-Chlorophenyl)carbamoyloxy]-4-pent-2-ynyl-trimethylammonium iodide (Cat. No. 0466) has been withdrawn from ... trimethylammonium chloride. J.Med.Chem. 35 2787 PMID: 1379640 View Related Products by Target. *Acetylcholine Muscarinic ... 4-[N-(4-Chlorophenyl)carbamoyloxy]-4-pent-2-ynyl-trimethyl ammonium iodide. Cat. No. 0466 COA / Product Datasheet SDS ... Reviews for 4-[N-(4-Chlorophenyl)carbamoyloxy]-4-pent-2-ynyl-trimethyl ammonium iodide. There are currently no reviews for this ...
... trimethylammonium Chloride (4-(Trifluoromethoxy)phenyl)hydrazonopropanedinitrile use Carbonyl Cyanide p- ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... N-trimethyl-1-propanaminium Chloride use Methacholine Chloride ... Trimethylammonium Butyrate use Butyrylthiocholine (2,4-dichlorophenoxy)acetic acid, butyl ester, mixt. with butyl (2,4,5- ... 8-Diamino-10-Methylacridinium Chloride Mixture With 2,8-Diaminoacridine use Acriflavine ...
... trimethylammonium Chloride 1 alpha,25-Dihydroxycholecalciferol use Calcitriol 1 alpha,25-Dihydroxyvitamin D3 use Calcitriol ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... 3,4-Benzopyrene use Benzo(a)pyrene 3,4-Dichloro-N-methyl-N-(2-( ... 2-Amino-5-phosphonovaleric Acid use 2-Amino-5-phosphonovalerate 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone use ... 2-Dehydro-3-Deoxyphosphoheptonate Aldolase use 3-Deoxy-7-Phosphoheptulonate Synthase 2-Fluoro-2-deoxy-D-glucose use ...
... trimethylammonium Chloride (4-(Trifluoromethoxy)phenyl)hydrazonopropanedinitrile use Carbonyl Cyanide p- ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... N-trimethyl-1-propanaminium Chloride use Methacholine Chloride ... Trimethylammonium Butyrate use Butyrylthiocholine (2,4-dichlorophenoxy)acetic acid, butyl ester, mixt. with butyl (2,4,5- ... 2-ME use Mercaptoethanol 2-N-Butyl-3-((2-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one use ...
Giri, B., Belanger, K., Seamon, M., Bradley, E., Purohit, S., Chong, R., Morgan, J. C., Baban, B. & Wakade, C., Sep 2 2019, In ... Chong, K. Y. R., Lee, K. H., Morgan, J. C. & Wakade, C. G., Aug 1 2015, In : Acta Neurologica Scandinavica. 132, 2, p. 105-110 ... Mahadik, S. P. & Wakade, C. G., Jan 1 1992, In : Drug Development Research. 27, 4, p. 307-327 21 p.. Research output: ... Bharucha, V. A., Wakade, C. G., Mahadik, S. P. & Karpiak, S. E., Oct 1991, In : Experimental Neurology. 114, 1, p. 136-139 4 p. ...
... trimethylammonium Chloride/pharmacology , Acetylcholinesterase/metabolism , Analysis of Variance , Blood Pressure/drug effects ... m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride/pharmacology (1) Order by. Year (decreasing). Relevance. Year ...
... trimethylammonium Chloride Medicine & Life Sciences * Muscarinic M1 Receptors Medicine & Life Sciences ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... The rank order of potency was 4-DAMP , pirenzepine , AFDX116 ... 1-2, 10.07.1992, p. 307-310.. Research output: Contribution to journal › Article ... The rank order of potency was 4-DAMP , pirenzepine , AFDX116 , (±)BN228 and McN-A-343. This profile, pirenzepines high potency ...
... trimethylammonium Chloride Medicine & Life Sciences * Synaptic Transmission Medicine & Life Sciences ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ...
... trimethylammonium Chloride. SQ-18506. 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole. ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... Ro 4-1284. 2H-Benzo(a)quinolizin-2-ol 2-Ethyl-1,3,4,6,7,11b- ... trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride. BW 284 C 51. Benzenaminium, 4,4-(3-oxo-1,5-pentanediyl)bis( ... Insulin-Like Growth Factor Binding Protein 4. Insulin-Like Growth Factor-Binding Protein 2. Insulin-Like Growth Factor Binding ...
... trimethylammonium Chloride. *Ambenonium Chloride. *Benzalkonium Compounds. *Benzethonium. *Benzylammonium Compounds. *Bephenium ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ...
... trimethylammonium Chloride , 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ... m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride , 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro- ... trimethylammonium Chloride , 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ... trimethylammonium Chloride , 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ...
... trimethylammonium Chloride A 41304 use Desoximetasone A 43818 use Leuprolide ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... AC133-2 Antigen use AC133 Antigen AC141 Antigen use AC133 ... A-sn-1,2-Diacylglycerol Acyltransferase, Palmitoyl-Coenzyme use Diacylglycerol O-Acyltransferase ... A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein use ADAMTS4 Protein ...
... trimethylammonium Chloride Chemical Compounds * Muscarinic Receptors Chemical Compounds * N-Methylscopolamine Chemical ... m-Chlorophenylcarbamoyloxy)-2-butynyl) ... S)-4-F-MePyMcN [(S)-4-(pyrrolidino)-1-methyl-2-butynyl-N-(4- ... N2 - (S)-4-F-MePyMcN [(S)-4-(pyrrolidino)-1-methyl-2-butynyl-N-(4- fluorophenyl) carbamate oxalate] has been suggested to be a ... AB - (S)-4-F-MePyMcN [(S)-4-(pyrrolidino)-1-methyl-2-butynyl-N-(4- fluorophenyl) carbamate oxalate] has been suggested to be a ...
  • Agonist binding to (-)-[ 3 H]QNB-labeled putative M 2 cardiac sites was more sensitive to Gpp(NH)p than (-)-[ 3 H]QNB-labeled cortical sites. (elsevier.com)
  • Whereas some selectivity remained with Gpp(NH)p present, M 2 selectivity of these agonists was modified by guanine nucleotides, as Gpp(NH)p lowered agonist affinity in the heart to values comparable to the cortex. (elsevier.com)
  • RESULTS: Both enalapril and losartan during perfusion into an adrenal vein for 90 minutes inhibited the CA release evoked by acetylcholine (ACh), 1.1-dimethyl-4-phenyl piperazinium (DMPP, a selective Nn agonist), high K+ (a direct membrane-depolarizer), 3-(m-chloro-phenyl-carbamoyl-oxy-2-butynyl-trimethyl ammonium (McN-A-343, a selective M1 agonist), and Ang II in a time-dependent manner. (bvsalud.org)
  • Also, in the presence of enalapril or losartan, the CA release evoked by veratridine (an activator of voltage-dependent Na+ channels), 6-dimethyl-3-nitro-4-(2-trifluoromethyl-phenyl)-pyridine-5-carboxylate (BAY-K-8644, an L-type Ca2+ channel activator), and cyclopiazonic acid (a cytoplasmic Ca2+-ATPase inhibitor) were significantly reduced. (bvsalud.org)