'Catha' is a plant species also known as Khat, Kat, or Qat. It contains psychoactive compounds that can cause stimulant-like effects when chewed, brewed into tea, or taken in other forms. The main active compound in Catha is cathinone, which is similar in structure and effects to amphetamines.

The use of Catha can produce feelings of euphoria, increased alertness, and talkativeness, but it can also cause side effects such as increased heart rate, blood pressure, and anxiety. Long-term use of Catha has been associated with a number of health problems, including tooth decay, gastrointestinal issues, and mental health disorders.

It's worth noting that the legal status of Catha varies by country and region. In some places, it is legal and widely used, while in others, it is considered a controlled substance and its use is restricted or prohibited.

Cathepsin A is a lysosomal protein that belongs to the peptidase family. It plays a role in various biological processes, including protein degradation and activation, cell signaling, and inflammation. Cathepsin A has both endopeptidase and exopeptidase activities, which allow it to cleave and process a wide range of substrates.

In addition to its enzymatic functions, cathepsin A also plays a structural role in the formation and stability of the protective protein complex called the "serglycin-cathepsin A proteoglycan complex." This complex protects certain proteases from degradation and helps regulate their activity within the lysosome.

Deficiencies or mutations in cathepsin A have been linked to several diseases, including a rare genetic disorder called galactosialidosis, which is characterized by developmental delays, coarse facial features, and progressive neurological deterioration.