• The Executive Board of the Council of State and Territorial Epidemiologists has approved the additions of "Zika virus disease, non-congenital infection" and "Zika virus congenital infection" to the list of nationally notifiable conditions reportable to the National Notifiable Diseases Surveillance System (NNDSS) beginning in 2016 ( 1 ). (cdc.gov)
  • Data for Zika virus disease, non-congenital infection have been displayed under "Arboviral diseases" in Table I of the MMWR Weekly Notifiable Diseases and Mortality Tables since February 5, 2016 ( 2 ). (cdc.gov)
  • Changes in the Presentation of Zika Virus Disease, Non-Congenital Infection, and Addition of Zika Virus Congenital Infection to Notifiable Diseases and Mortality Table I. MMWR Morb Mortal Wkly Rep 2016;65:524. (cdc.gov)
  • The study, which drew on data from two cohorts of Nicaraguan children who lived through a Zika epidemic in 2016 and a dengue epidemic in 2019, is the first to investigate the impacts of Zika immunity on dengue disease in humans. (sciencedaily.com)
  • When chikungunya, another mosquito-borne virus, and Zika appeared in Nicaragua in 2014 and 2016, respectively, the cohort was expanded to capture cases of these emerging pathogens. (sciencedaily.com)
  • The two arrived at the very beginning of what would become a massive epidemic of dengue virus Type 2, one of the more severe of the four flavors, or serotypes, of dengue, and the first major outbreak of dengue since the Zika epidemic in 2016. (sciencedaily.com)
  • Office of Management and Budget approval of the NNDSS Revision, 0920-0728 on January 21, 2016, authorized CDC to receive case notifications for Zika virus disease, non-congenital infection and Zika virus, congenital infection. (cdc.gov)
  • In 2016 and 2017, cases of locally transmitted Zika virus infection were reported in Miami-Dade County in southeastern Florida and Brownsville, Texas. (msdmanuals.com)
  • 03 March 2016 - The World Health Organization (WHO) Regional Office for the Eastern Mediterranean invited representatives from ministries of health in the Region to 2 rounds of emergency meetings to share information on Zika virus infection and associated conditions and discuss implementation of public health measures to prepare for, and respond to, any possible spread in the Region. (who.int)
  • The proportion of asymptomatic infections and spectrum of disease among pregnant women infected by Zika virus: systematic monitoring in French Guiana, 2016. (bvsalud.org)
  • During 2014-2016, the pandemics of chikungunya and Zika virus transiently inserted those diseases into the top 5. (health.mil)
  • Bangladesh A human blood sample that was obtained in 2014 was confirmed to have Zika virus by Bangladesh's health ministry on 22 March 2016. (wikipedia.org)
  • This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2016 by CSTE for national surveillance, that were implemented in January 2017, including updated surveillance case definitions for salmonellosis, shigellosis, vibrioisis, perinatal hepatitis B virus infection, invasive pneumococcal disease, Lyme disease, and tularemia reported through August 7, 2018. (cdc.gov)
  • Davidson A, Slavinski S, Komoto K, Rakeman J, Weiss D. Suspected female-to-male sexual transmission of Zika virus - new York City, 2016. (springer.com)
  • Male-to-male sexual transmission of Zika virus--Texas, January 2016. (springer.com)
  • Evidence suggesting an association of Zika virus infection with an increased risk for congenital microcephaly and other abnormalities of the brain and eye ( 5 ) prompted the World Health Organization to declare the Zika virus outbreak a Public Health Emergency of International Concern on February 1, 2016 ( http://www.who.int/mediacentre/news/statements/2016/1st-emergency-committee-zika/en/ external icon ). (cdc.gov)
  • In the terse dispatch from Jan. 15, 2016, entitled "CDC issues interim travel guidance related to Zika virus for 14 Countries and Territories in Central and South America and the Caribbean," the CDC counseled pregnant women to consider delaying travel to affected areas and those who are trying to become pregnant to "consult their doctor. (thedailybeast.com)
  • In 2016, in response to the WHO declaration, the Thai government called on hospitals in the country to collect urine, blood and plasma samples from people with symptoms that may be associated with Zika, in other words, people with fever or rash symptoms. (medindia.net)
  • [6] As of 2016, there is no medication or vaccine that can prevent the Zika virus. (wikipedia.org)
  • In January 2016, the United States Centers for Disease Control and Prevention (CDC) published advice for how to avoid getting Zika fever. (wikipedia.org)
  • On February 2, 2016, public health officials in Dallas County, Texas , reported the first case of somebody getting Zika virus in the United States. (wikipedia.org)
  • Buffalo, NY (PRWEB) February 03, 2016 -- ZeptoMetrix™ Corporation (ZMC), announced today the release of several new products to aid in the rapid development and ongoing quality control of molecular assays targeting the Zika Virus. (prweb.com)
  • dengue, which can develop into the potentially fatal disease dengue fever, and Zika, which caused a global medical emergency in 2016. (leeds.ac.uk)
  • As of October 12, 2016 the Centers for Disease Control and Prevention reported 3,936 cases of ZIKV infection, with two Florida cities identified as the Ground Zero for local transmission. (jcvi.org)
  • As of September 2016, the ViPR Zika portal contains 389 genomic and 2399 protein sequences representing the three major Zika lineages - East African, West African and Asian. (jcvi.org)
  • In the spring of 2016, there was a frenzy over the threat of Zika virus at Brazil's Olympic Games. (wvxu.org)
  • Among 28,219 nonpregnant persons with laboratory evidence of Zika virus disease identified in Puerto Rico during November 1, 2015-October 20, 2016, incidence was highest among women aged 20-49 years. (cdc.gov)
  • Encefalitis en IDWeek 2016 con la Dra. (medscape.com)
  • On 1 February 2016, the World Health Organization (WHO) declared the Zika epidemic a Public Health Emergency of International Concern (PHEIC). (who.int)
  • Chikungunya Disease Chikungunya disease is transmitted by the Aedes mosquito. (msdmanuals.com)
  • Chikungunya disease usually presents with acute fever. (msdmanuals.com)
  • Like the dengue and chikungunya viruses, the zika virus is also transmitted by the mosquito Aedes aegypti . (fapesp.br)
  • mosquitoes are found throughout much of the Americas, including parts of the United States, and also transmit dengue and chikungunya viruses. (cdc.gov)
  • The recent re-emergence and travel-related spread of Chikungunya infection to Europe and the United States has drawn global attention. (medscape.com)
  • The term "Chikungunya" often refers to both the virus (CHIKV) and the illness or fever (CHIKF) caused by this virus. (medscape.com)
  • The exact pathophysiology of Chikungunya virus remains to be investigated. (medscape.com)
  • Chikungunya virus infection has a clinical presentation that overlaps with that of Ross River virus infection (fever, rash, polyarthritis) and dengue fever transmitted by the same mosquitoes. (medscape.com)
  • Using a murine model, Lum et al showed that anti-Chikungunya virus antibodies were elicited early in the course of the illness and were directed against the C-terminus of the viral E2 glycoprotein. (medscape.com)
  • Both natural and Chikungunya virus infection-induced specific antibodies were essential for controlling Chikungunya virus infections. (medscape.com)
  • Chikungunya virus infection elicited strong innate immunity with an abundant production of proinflammatory markers and cytokines, including high levels of alpha interferon, interleukin (IL)-4, IL10, and gamma interferon. (medscape.com)
  • A 2017 study reported that Chikungunya infection activates toll-like receptors (TLR), triggering the innate immune system. (medscape.com)
  • [ 23 , 24 ] Bernard et al evaluated this mechanism and found that Chikungunya virus enters mammalian epithelial cells via a clathrin-independent, Esp-15-dependent, dynamin 2-dependent route and requires an endocytic pathway in combination with other unknown pathways. (medscape.com)
  • The authors speculate that Chikungunya virus is capable of undergoing genetic drifts and could acquire alternate entry mechanisms. (medscape.com)
  • Several murine models with Chikungunya virus-related joint and neurological diseases are being investigated. (medscape.com)
  • the report excludes chikungunya, dengue, yellow fever, and Zika virus disease cases, because these infections were acquired primarily through travel during 2021. (medscape.com)
  • These mosquitoes can also transmit dengue and chikungunya viruses ( 4 ). (cdc.gov)
  • All travelers to or residents of areas with ongoing Zika virus transmission should be advised to strictly follow steps to avoid mosquito bites because of the potential for exposure to Zika, dengue, and chikungunya viruses ( 6 ). (cdc.gov)
  • To prevent human-to-mosquito-to-human transmission, persons infected with Zika, dengue, or chikungunya virus should protect themselves from mosquito exposure during the first week of illness. (cdc.gov)
  • But a new virus causing a rare nightmarish birth defect simply has not been seen with any of the recent waves of comparably frightening and lethal new outbreaks-not HIV, not SARS, not Ebola, not chikungunya. (thedailybeast.com)
  • In a press conference on the rise of dengue, Zika, and chikungunya outbreaks and the impact of climate change, WHO officials expressed great concern about the region of the Americas. (medscape.com)
  • There's no specific treatment for any of those three arboviral diseases, [ meaning Zika, dengue, and chikungunya]. (medscape.com)
  • While Zika is the greatest concern, dengue fever, Chikungunya virus and yellow fever are also spread by the Aedes aegypti mosquito. (salon.com)
  • Vaccines and antivirals are not available to prevent or treat Zika and other mosquito-borne viral diseases, such as dengue fever and Chikungunya virus. (salon.com)
  • Other arboviruses from the ZeptoMetrix collection, such as Dengue Virus, Yellow Fever, and Chikungunya can be used to test that an assay is specific for the Zika Virus. (prweb.com)
  • There are currently no specific treatments or vaccines for dengue, Zika, and other potentially serious mosquito-borne viruses including Chikungunya, West Nile virus, Semliki Forest virus and Rift Valley fever virus. (leeds.ac.uk)
  • In March, the FDA granted an EUA to the Trioplex Real-Time RT-PCR Assay , which was developed by the US Centers for Disease Control and Prevention and tests patient samples for Zika, chikungunya, and dengue virus infection. (genomeweb.com)
  • The Zika virus, like the chikungunya and West Nile viruses, originated in Africa and are now being chiefly spread by the Aedes aegypti mosquito. (reason.com)
  • But there is another promising way to control Zika-control the mosquitoes that carry it and other diseases like dengue, malaria, chikungunya and West Nile virus. (reason.com)
  • Zika is transmitted by Aedes aegypti mosquitoes -- the same mosquitoes that carry dengue and chikungunya viruses, and that were historically responsible for yellow fever. (nsf.gov)
  • The yellow fever mosquito, Aedes aegypti , spreads dengue fever, Zika, chikungunya and other viruses that infect humans. (smithsonianmag.com)
  • They tested the blood for antibodies for Zika virus, along with other viruses carried by mosquitoes in the area: chikungunya, West Nile virus and dengue. (wvxu.org)
  • Out of those 457 people tested, 32 people came back with antibodies to mosquito-borne viruses they hadn't had in their blood before: Three for chikungunya, two for dengue and 27 for West Nile virus. (wvxu.org)
  • Zika virus infection during pregnancy can cause microcephaly (a serious birth defect), eye abnormalities, and a number of developmental impairments termed congenital Zika syndrome. (msdmanuals.com)
  • Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths (and other events such as their first reported cases of microcephaly and major public health announcements), and relevant sessions and announcements of the World Health Organization (WHO), and the U.S. Centers for Disease Control (CDC), as well as relevant virological, epidemiological, and entomological studies. (wikipedia.org)
  • 1) describe the epidemiology, clinical manifestation, management and prevention of Zika virus disease, 2) discuss diagnostic testing for Zika virus infection and interpretation of test results, 3) articulate the importance of early recognition and reporting of cases, 4) state the recommendations for pregnant women and possible Zika virus exposure, and 5) discuss evaluation of infants with microcephaly and relationship of Zika in microcephaly. (cdc.gov)
  • Administering the molecule, called 25-hydroxycholesterol or 25HC, to pregnant mice reduced Zika virus infection in the fetal brain and protected against Zika-induced microcephaly. (blogspot.com)
  • To determine whether 25HC could protect against Zika-induced microcephaly, the researchers gave pregnant mice 25HC or placebo before and for five days after their embryos were infected with Zika virus. (blogspot.com)
  • The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects. (news-medical.net)
  • This situation has created an alarming public health emergency of international concern requiring the detection of this life-threatening viral candidate due to increased cases of newborn microcephaly associated with ZIKV infection. (frontiersin.org)
  • Unlike the birth defect microcephaly, which previously had not been associated with Zika virus, the connection between GBS and Zika already has been established. (thedailybeast.com)
  • Since then, infection and microcephaly have been seen in many additional countries, including an American who had lived in Brazil . (thedailybeast.com)
  • The odd part about the situation, though, remains the inability to confirm without doubt the association between Zika and microcephaly. (thedailybeast.com)
  • From what we have been told, the virus has been found in many, but not all, of the infants born with the condition and the number of mothers of babies with microcephaly is reportedly "high. (thedailybeast.com)
  • Zika virus infection is a zoonosis which is associated with congenital birth defects, with microcephaly the most widely known. (radiopaedia.org)
  • Previous outbreaks of the disease have shown there is an association between Zika infection during pregnancy and babies born with microcephaly . (salon.com)
  • Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg? (wikipedia.org)
  • Scientists provide a potential biological link between Zika virus infection and microcephaly. (the-scientist.com)
  • The study, albeit preliminary, offers the first suggestion of how Zika infection of pregnant women might lead to microcephaly in their babies. (the-scientist.com)
  • On hearing about the Zika-microcephaly crisis in Brazil, Ming realized she had a unique opportunity to examine whether human neural progenitor cells might be susceptible to infection. (the-scientist.com)
  • They are concerned that the recent steep rise in cases of microcephaly in Brazil is linked to the virus. (reason.com)
  • Besides the association with microcephaly, Zika is also suspected of boosting the incidence of the paralyzing Guillain-Barre syndrome. (reason.com)
  • Usually a relatively mild illness, Zika may be linked with birth defects such as microcephaly, and with the neurological disorder Guillain-Barre Syndrome. (nsf.gov)
  • The first outbreak of the Zika virus occurred in Brazil in 2015, becoming a serious public health problem due to the increase in the number of cases of microcephaly in infected pregnant women. (bvsalud.org)
  • However, the Region remains at risk as the Aedes mosquito that transmits the virus to humans is present in at least 8 countries - Djibouti, Egypt, Oman, Pakistan, Saudi Arabia, Somalia, Sudan and Yemen. (who.int)
  • Uganda The Zika virus is first isolated in 1947 in a rhesus monkey in the Zika Forest near Entebbe, Uganda, and first recovered from an Aedes africanus mosquito in 1948. (wikipedia.org)
  • Zika virus is a mosquito-borne flavivirus transmitted primarily by Aedes aegypti mosquitoes. (cdc.gov)
  • Zika virus is transmitted primarily by Aedes aegypti mosquitoes ( 1 , 7 ). (cdc.gov)
  • Aedes albopictus mosquitoes also might transmit the virus. (cdc.gov)
  • Aedes aegypti mosquitos transmit the Zika virus to humans. (hopkinsmedicine.org)
  • Zika virus (ZIKV) is mainly transmitted through Aedes mosquito bites, but sexual and post-transfusion transmissions have been reported. (springer.com)
  • Zika virus in Gabon (Central Africa) - 2007: a new threat from Aedes albopictus? (springer.com)
  • The reported occurrences of ZIKV infections are thought to be transmitted mainly by the mosquito species Aedes aegypti and Aedes albopictus . (frontiersin.org)
  • Zika virus is primarily transmitted by Aedes aegypti mosquitoes, which are found throughout much of the region of the Americas, including parts of the United States ( 2 , 3 ). (cdc.gov)
  • Zika is a single RNA stranded flavivirus usually transmitted by a mosquito vector , for example, Aedes aegypti . (radiopaedia.org)
  • The Aedes mosquito - potentially together with flaviviruses like dengue and Zika - is found in most tropical and subtropical countries, and South-East Asia is no exception. (medindia.net)
  • Zika virus is a disease spread to humans primarily through the bite of infected Aedes aegypti mosquitoes. (salon.com)
  • Although the current number of confirmed cases of Zika in Florida and Texas is not large, the growth of the Aedes aegypti mosquito greatly increases the chance the disease will begin to spread. (salon.com)
  • Last fall, researchers at the University of Missouri reported a proof of concept experiment in which they used the fantastic CRISPR gene-editing technique to create Aedes aegypti mosquitoes that would pass along disease resistance genes to all of their progeny . (reason.com)
  • These two diseases are transmitted to humans by mosquitoes of the Aedes genus, for which surveillance has been stepped up in France from May to November 2018 since the tiger mosquito ( Aedes albopictus ) is now present in 42 French départements, twice as many as two years ago. (pasteur.fr)
  • A few days after a female Aedes aegypti mosquito bites a virus-infected person, the mosquito can develop its own infection, which it then transmits to the next person it bites, says Erin Mordecai, an ecologist and infectious disease specialist at Stanford University. (nsf.gov)
  • Unlike other mosquitoes that bite people only in the evening, Aedes aegypti bites throughout the day, increasing exposure to viruses like Zika. (nsf.gov)
  • A group led by Mordecai is studying the socio-ecology and climate responses of dengue and Zika virus transmission by catching Aedes aegypti mosquitoes at three sites in southern coastal Ecuador. (nsf.gov)
  • In recent studies, Machala had the highest abundance of Aedes aegypti larvae of all sites surveyed in 10 countries in Latin America and Asia, indicating high risk for virus transmission. (nsf.gov)
  • By collecting weather and social data, the group hopes to discover the socioeconomic and environmental factors that put people most at risk for diseases carried by Aedes aegypti . (nsf.gov)
  • Studying interacting factors allows researchers to understand the "risk landscape" for Aedes- transmitted diseases, according to Sadie Ryan, an ecologist and medical geographer at the University of Florida who is collaborating on the research. (nsf.gov)
  • The study will start in Puerto Rico and expand to Brazil, Colombia, and other areas where Zika has been transmitted to people by Aedes aegypti mosquitoes. (acs.org)
  • In the first part of their multi-step study, Cheng's team tested whether two species of mosquitoes, Aedes aegypti and Aedes albopictus , were more attracted to Zika or dengue infected mice than to uninfected mice. (smithsonianmag.com)
  • In 1947, the Zika virus was first isolated from monkeys in the Zika Forest of Uganda but was not considered an important human pathogen until the first large-scale outbreaks in the South Pacific islands in 2007. (msdmanuals.com)
  • The Centers for Disease Control and Prevention (CDC) issues travel alerts for countries in these regions when outbreaks occur. (msdmanuals.com)
  • Although as of December 2019, there were no areas with CDC travel precautions due to Zika outbreaks, in early 2020 there were thousands of cases in some areas of Brazil and hundreds of cases in Colombia. (msdmanuals.com)
  • In light of the recent outbreaks in the Americas, the number of Zika virus disease cases among travelers visiting or returning to the United States is likely to increase. (cdc.gov)
  • During outbreaks, humans are the primary amplifying host for Zika virus. (cdc.gov)
  • Other arboviruses cause sporadic cases of disease as well as occasional outbreaks. (medscape.com)
  • Recent outbreaks of ZIKV infections have become fatal on a daily basis in the Americas, where this obscure viral candidate has been placed at the forefront of global healthcare. (frontiersin.org)
  • As mentioned, the paralysis from Zika is not a surprise given a previous observation from other Zika outbreaks and the settled fact that this can happen after an array of viral infections, including some from close genetic cousins of Zika. (thedailybeast.com)
  • But unlike South America, South-East Asia has not recorded widespread Zika outbreaks. (medindia.net)
  • However, it has been unclear whether there represented a true absence of the virus in the region or if outbreaks have simply not been detected. (medindia.net)
  • Zika and dengue are transmitted by the same mosquito, so dengue maps and statistics provided data to decision-makers to help identify areas that were likely at greater risk for Zika outbreaks. (cdc.gov)
  • This capability uniquely positions Quest to complement the response of public health laboratories for Zika outbreaks where access to FDA-authorized diagnostic tests can potentially influence the quality of patient management. (genomeweb.com)
  • The Zika virus is a mosquito-borne flavivirus that is antigenically and structurally similar to the viruses that cause dengue, yellow fever, and West Nile virus. (msdmanuals.com)
  • Zika virus is a single-stranded RNA virus in the genus flavivirus, family flaviviridae that is closely related to dengue, yellow fever, Japanese encephalitis and West Nile viruses. (cdc.gov)
  • Their initial cell culture experiments indicated that 25HC can block Zika and related viruses, including dengue and yellow fever viruses, from entering cells. (blogspot.com)
  • Saint Louis University's Center for Vaccine Development is studying an investigational vaccine for yellow fever, a potentially deadly disease that is spread by the same mosquito that transmits Zika virus. (news-medical.net)
  • Zika virus is related to West Nile virus and the viruses that cause dengue fever , yellow fever , and Japanese encephalitis . (wikipedia.org)
  • They are the primary vectors for major human diseases such as yellow fever, malaria, and dengue fever, which together infect hundreds of millions of humans worldwide and kill millions each year. (healthline.com)
  • Candida auris, clinical became a new national notifiable condition, and revised case definitions were implemented for the following conditions: diphtheria, acute hepatitis A, listeriosis, yellow fever, Salmonella Paratyphi infection and Salmonella Typhi infection. (cdc.gov)
  • Two of these protein receptors, RIG-I and MDA5, had previously been identified as playing a key role in the innate response against the replication of flaviviruses, a family of mosquito-borne viruses that includes dengue, yellow fever and Zika. (pasteur.fr)
  • Yellow fever is a mosquito-borne disease that is endemic to tropical South America and Sub-Saharan Africa (see the image below). (medscape.com)
  • Their new study published today in Cell reveals that mosquitoes become more attracted to hosts that are infected with both flaviviruses , diseases in the same family as West Nile and yellow fever. (smithsonianmag.com)
  • 2017) Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. (radiopaedia.org)
  • In 2017, substantial progress has been made towards the development, immunological analysis and preclinical evaluation of vaccine platforms to prevent the pathologies associated with ZIKV infection. (nature.com)
  • By analyzing blood serum samples from eight of these patients, researchers from the Carlos Chagas Institute at the Oswaldo Cruz Foundation in the city of Curitiba, state of Paraná, and from the Institute of Tropical Medicine at the Federal University of Rio Grande do Norte were able to determine the culprit: the ZIKV virus, responsible for zika fever ( Memórias do Instituto Oswaldo Cruz , June 2015). (fapesp.br)
  • Zika virus ( ZIKV ) infection has been associated with complications during pregnancy . (bvsalud.org)
  • We enrolled 3,050 pregnant women aged 14-48 years and 573 (19%) had laboratory -confirmed ZIKV infection . (bvsalud.org)
  • 23% of them (95% confidence interval (CI) 20-27) had at least one symptom compatible with ZIKV infection . (bvsalud.org)
  • These estimates put findings on cohorts of symptomatic ZIKV -positive pregnant women into the wider context of an epidemic with mainly asymptomatic infections . (bvsalud.org)
  • The proportion of symptomatic ZIKV infections appears to vary substantially between populations . (bvsalud.org)
  • During acute infection, ZIKV is detectable in most organs and body fluids including human semen. (springer.com)
  • So far, the consensus is that ZIKV infection in the testes or epididymis might affect sperm development and, consequently, male fertility. (springer.com)
  • This manuscript provides an updated overview of the cellular and molecular mechanisms of ZIKV infection and reviews data on ZIKV persistence in semen and associated risks to the male reproductive system described in human and animal models studies. (springer.com)
  • In the light of the identified gaps in our accumulated knowledge on the subject, we highlight the importance for couples seeking ART to follow the constantly revised guidelines and the need of specific ZIKV diagnosis tools for semen screening to contain ZIKV virus spread and make ART safer. (springer.com)
  • The current scenario regarding the widespread Zika virus (ZIKV) has resulted in numerous diagnostic studies, specifically in South America and in locations where there is frequent entry of travelers returning from ZIKV-affected areas, including pregnant women with or without clinical symptoms of ZIKV infection. (frontiersin.org)
  • Previously, only sporadic cases of negligible concern associated with human ZIKV infection were reported ( Hayes, 2009 ). (frontiersin.org)
  • Considering the calamity of ZIKV infection, there is an urgent need to develop rapid detection methods for ZIKV along with DENV, which shares common clinical symptoms with ZIKV. (frontiersin.org)
  • Zika virus (ZIKV) infection usually is mild and self-limited. (medscape.com)
  • Multiple antiviral drugs are under investigation for treatment of ZIKV infection. (medscape.com)
  • Moreover, any approved anti-Zika drug should be reasonably-priced as the majority of the ZIKV circulation occurs in tropical and sub-tropical countries with limited-resources. (medscape.com)
  • The rapidly developing Zika virus (ZIKV) outbreak has research groups, government agencies, and industry is all striving to develop a response plan to contain and ultimately prevent ZIKV spread. (jcvi.org)
  • We expect these efforts to guide the rational design of ZIKV antivirals and vaccines to treat and prevent ZIKV-induced disease. (jcvi.org)
  • In each area, additional funding would accelerate our efforts to understand and ultimately control ZIKV infection in the human population. (jcvi.org)
  • JCVI, through an existing NIH funded grant, is working with the Biodefense and Emerging Infections Research Resources Repository (BEI Resources) to provide high quality sequence data for publically available ZIKV strains. (jcvi.org)
  • Over the upcoming year, JCVI anticipates screening both retrospective and prospective human serum samples for ZIKV, with the assumption that many of these samples are from individuals infected with other viral diseases (e.g. (jcvi.org)
  • To distinguish between ZIKV and other viral diseases, we are developing a highly sensitive and specific ZIKV diagnostic PCR assay. (jcvi.org)
  • Over the past 2 years, Zika virus (ZIKV) has emerged as a pathogen capable of causing devastating congenital malformations in the developing fetus and significant neurological disease in adults. (nature.com)
  • This article describes Viet Nam Ministry of Health's (VMoH) activities to prepare for and respond to the threat Zika virus (ZIKV), including the adaptation of existing surveillance systems to encompass ZIKV surveillance. (who.int)
  • The GDPM, the central public health agency within the VMoH, created the ZIKV response plan, including training health-care workers to recognize and report ZIKV infection, strengthening surveillance and building ZIKV diagnostic testing capacity. (who.int)
  • Teams made up of trainers from the GDPM, the Medical Services Administration, the Maternal and Child Health Department, the Health Communication and Education Department and international experts from WHO and the United States Centers for Disease Control and Prevention (CDC) were deployed to each region to train clinicians to recognize and report ZIKV. (who.int)
  • An existing sentinel surveillance system for the dengue virus was expanded in eight southern provinces to include ZIKV, as the clinical presentations of the two diseases are very similar. (who.int)
  • An additional 221 dengue-negative specimens that were collected by the dengue surveillance system in 2015 were tested for ZIKV to detect historical infections. (who.int)
  • A. albopictus is thought to be a secondary vector of epidemic Zika virus infection in the tropics, but whether it would do so in the more temperate climate of the United States is unclear. (msdmanuals.com)
  • According to the researchers, identifying the zika virus as being responsible for an epidemic of the disease in northeastern Brazil makes this the first report of autochthonous transmission (within the same state or city) of zika fever in Brazil. (fapesp.br)
  • This article primarily covers the chronology of the 2015-16 Zika virus epidemic. (wikipedia.org)
  • Although it is not currently epidemic, there is a concern that the virus can still reemerge since the male genital tract might harbor persistent reservoirs that could facilitate viral transmission over extended periods, raising concerns among public health and assisted reproductive technologies (ART) experts and professionals. (springer.com)
  • The sudden emergence of the Zika virus epidemic in Latin America in 2015-16 has caught the scientific world unawares. (news-medical.net)
  • Overview: What Is Zika and How Did It Become Epidemic? (frontiersin.org)
  • Rapid risk assessment: Zika virus disease epidemic. (nric.org.uk)
  • This large prospective study promises to provide important new data that will help guide the medical and public health responses to the Zika virus epidemic," says Anthony S. Fauci, director of the National Institute of Allergy & Infectious Diseases, one of the NIH centers supporting the research. (acs.org)
  • And it makes sense when you look at the chart of known Zika cases over time - by the time the Olympics started, the peak of the epidemic had passed. (wvxu.org)
  • Until more is known, pregnant women should consider postponing travel to any area with ongoing Zika virus transmission. (cdc.gov)
  • Updated guidelines include a new recommendation to offer serologic testing to asymptomatic pregnant women (women who do not report clinical illness consistent with Zika virus disease) who have traveled to areas with ongoing Zika virus transmission. (cdc.gov)
  • This update also expands guidance to women who reside in areas with ongoing Zika virus transmission, and includes recommendations for screening, testing, and management of pregnant women and recommendations for counseling women of reproductive age (15-44 years). (cdc.gov)
  • Pregnant women who reside in areas with ongoing Zika virus transmission have an ongoing risk for infection throughout their pregnancy. (cdc.gov)
  • For asymptomatic pregnant women residing in areas with ongoing Zika virus transmission, testing is recommended at the initiation of prenatal care with follow-up testing mid-second trimester. (cdc.gov)
  • The Zika virus outbreak continues to spread ( http://www.cdc.gov/zika/geo/index.html ), with ongoing Zika virus transmission recently reported in U.S. territories. (cdc.gov)
  • Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Epstein-Barr Virus (HHV-4) Infections - Drugs In Development, 2021, provides an overview of the Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline landscape.Epstein-Barr virus (EBV) or human herpes virus 4 virus is a member of the Herpesviridae family. (marketresearch.com)
  • Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Epstein-Barr Virus (HHV-4) Infections - Drugs In Development, 2021, provides comprehensive information on the therapeutics under development for Epstein-Barr Virus (HHV-4) Infections (Infectious Disease), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (marketresearch.com)
  • The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.The Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline guide also reviews of key players involved in therapeutic development for Epstein-Barr Virus (HHV-4) Infections and features dormant and discontinued projects. (marketresearch.com)
  • Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (marketresearch.com)
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Epstein-Barr Virus (HHV-4) Infections (Infectious Disease). (marketresearch.com)
  • The pipeline guide reviews pipeline therapeutics for Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) by companies and universities/research institutes based on information derived from company and industry-specific sources. (marketresearch.com)
  • The pipeline guide reviews key companies involved in Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) therapeutics and enlists all their major and minor projects. (marketresearch.com)
  • The pipeline guide evaluates Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (marketresearch.com)
  • Medscape 's Portuguese edition spoke with André Siqueira, MD, PhD, an infectious disease specialist and researcher at the Laboratory of Acute Febrile Diseases at the Oswaldo Cruz Foundation's Evandro Chagas National Institute of Infectious Diseases. (medscape.com)
  • Zika virus can cause an infectious disease called Zika fever . (wikipedia.org)
  • ZeptoMetrix Corporation (ZMC) is a renowned industry leader and innovator identified with quality, reliable and trusted products and services for infectious disease diagnostic development. (prweb.com)
  • Quest's expertise in molecular, infectious disease, and women's health diagnostics, and relationships with half of the country's physicians and hospitals, allow us to quickly make useful tests widely available for clinical use," Pesano added. (genomeweb.com)
  • Standard Precautions should be used to protect healthcare personnel from all infectious disease transmission, including Zika virus. (cdc.gov)
  • In May 2015, the first local transmission of Zika virus in the Region of the Americas was reported in Brazil. (cdc.gov)
  • Although local transmission of Zika virus has not been documented in the continental United States, infections have been reported among travelers visiting or returning to the United States, and these likely will increase. (cdc.gov)
  • In May 2015, the World Health Organization reported the first local transmission of Zika virus in the Region of the Americas (Americas), with autochthonous cases identified in Brazil ( 4 ). (cdc.gov)
  • Although local transmission of Zika virus has not been documented in the continental United States, Zika virus infections have been reported in returning travelers ( 7 ). (cdc.gov)
  • Potential sexual transmission of Zika virus. (springer.com)
  • French Polynesia On 31 March, researchers on Tahiti report that 2.8% of blood donors between November 2013 and February 2014 tested positive for the Zika virus, of which 3% were asymptomatic at the time of blood donation. (wikipedia.org)
  • Most infections are asymptomatic, and symptomatic disease generally is mild. (cdc.gov)
  • An estimated 80% of persons who are infected with Zika virus are asymptomatic ( 2 ). (cdc.gov)
  • In a minority of cases, HEV causes acute and chronic hepatitis, but infection is commonly asymptomatic or unrecognized. (nature.com)
  • Whereas most human infections are asymptomatic, symptomatic infections commonly manifest as a systemic febrile illness and less commonly as neuroinvasive disease. (medscape.com)
  • Local health officials should determine when to implement testing of asymptomatic pregnant women based on information about levels of Zika virus transmission and laboratory capacity. (cdc.gov)
  • In up to 80% of adult cases, Zika disease is asymptomatic. (radiopaedia.org)
  • Prevention involves avoiding mosquito bites, avoiding unprotected sex with a partner at risk of having Zika virus infection, and, for pregnant women and their partners, avoiding travel to areas with ongoing transmission. (msdmanuals.com)
  • CDC has updated its interim guidelines for U.S. health care providers caring for pregnant women during a Zika virus outbreak ( 1 ). (cdc.gov)
  • For pregnant women with clinical illness consistent with Zika virus disease,* testing is recommended during the first week of illness. (cdc.gov)
  • The greatest threat posed by Zika is the risk of infection among pregnant women . (salon.com)
  • Pregnant women who get the Zika virus can spread the virus to their fetuses . (wikipedia.org)
  • [13] [14] Colombia , the Dominican Republic , Ecuador , El Salvador , and Jamaica advised women not to get pregnant until scientists know more about the risks of Zika virus to pregnant women. (wikipedia.org)
  • [ 33 ] Managament of pregnant women with Zika and infants with Congenital Zika syndrome requires specialist consultation and care. (medscape.com)
  • Overall, there have been multiple challenges associated with development of anti-Zika drugs as these drugs should be able to cross blood-brain barrier and placental barrier in pregnant women and should be safe for consumption during pregnancy. (medscape.com)
  • Pregnant women should avoid traveling to countries with active transmission of Zika, including Florida's Miami-Dade County. (sdaho.org)
  • State Epidemiologist Dr. Lon Kightlinger says travelers to Zika-affected areas, particularly pregnant women, should follow strict mosquito control precautions. (sdaho.org)
  • Here's what you can do while you're pregnant to protect yourself and your baby from infections. (healthychildren.org)
  • Stay away from anyone who has these infections if you have not yet had them yourself or if you didn't have the vaccine(s) before you got pregnant. (healthychildren.org)
  • Public health officials are warning pregnant women to avoid being bitten by mosquitoes that might be carrying the Zika virus. (reason.com)
  • NIH and a Brazilian health research agency have launched an international study of almost 10,000 pregnant women in Zika-affected areas. (acs.org)
  • Infection with the Zika virus causes small heads and other neurological birth defects in some children whose mothers contracted the disease while pregnant. (acs.org)
  • A number of athletes, worried about sexually transmitting the virus to pregnant partners, chose to stay home. (wvxu.org)
  • The interactive clinical algorithm allows healthcare providers to receive recommendations tailored to their pregnant patients with possible Zika exposure. (cdc.gov)
  • PHAC no longer recommends that pregnant women or women who are trying to conceive avoid travelling to countries or areas with risk of Zika virus. (canada.ca)
  • PHAC continues to recommend that pregnant women avoid travelling to areas with a current Zika virus outbreak. (canada.ca)
  • Zika virus infection in a pregnant woman can pose significant risks to the unborn baby, even if the woman does not develop symptoms. (canada.ca)
  • If you are pregnant and think you have been exposed to or infected with Zika virus, contact your health care professional. (canada.ca)
  • perspectives of abortion for the pregnant woman with Zika virus regarding the medical, emotional and social consequences. (bvsalud.org)
  • Dr. Cynthia Moore is a director of the Division of Birth Defects and Developmental Disabilities at the Centers for Disease Control and Prevention. (cdc.gov)
  • Additional preclinical research is needed before investigating whether 25HC can safely protect humans against Zika virus infection and associated birth defects. (blogspot.com)
  • In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute have elucidated how the virus attacks the brains of newborns, information that could accelerate the development of treatments. (news-medical.net)
  • Stopping the explosive spread of Zika virus - which can lead to birth defects in babies born to infected mothers - depends on genetic insights gleaned through new tools and models. (news-medical.net)
  • We still don't know enough about Brazil's Zika virus, which has been linked to birth defects and a paralytic condition called Guillain-Barré. (thedailybeast.com)
  • Local public health authorities announced that, in addition to severe birth defects, the infection may be linked to a paralytic condition called Guillain-Barré Syndrome, or GBS . (thedailybeast.com)
  • The impact of Zika virus, therefore, will be even more catastrophic than first feared a few weeks ago when the possible connection between infection during pregnancy and severe birth defects caught the world's attention. (thedailybeast.com)
  • Infected mosquitos can transmit viruses like the Zika virus , which has been linked to birth defects. (healthychildren.org)
  • Additional data reported to the US Zika Pregnancy Registry for outcomes of pregnancies with laboratory evidence of possible Zika virus infection are available at https://www.cdc.gov/pregnancy/zika/data/pregnancy-outcomes.html . (cdc.gov)
  • Cases reported to the US Zika Pregnancy Registry might not meet the national surveillance case definition for congenital Zika virus disease or infection. (cdc.gov)
  • For the first time, abnormal brain development following a Zika infection during pregnancy has been documented experimentally in the offspring of a non-human primate. (news-medical.net)
  • Health care providers should discuss reproductive life plans, including pregnancy intention and timing, with women of reproductive age in the context of the potential risks associated with Zika virus infection. (cdc.gov)
  • Expert consultation with a maternal-fetal medicine and infectious diseases specialists is advised for management of Zika virus infection during pregnancy. (medscape.com)
  • Infections during pregnancy can hurt both you and your baby. (healthychildren.org)
  • Tick​ bites can spread diseases like Lyme disease too, which can cause pregnancy complications if it's left untreated. (healthychildren.org)
  • CDC and state, tribal, local, and territorial health departments request that healthcare providers, especially obstetric and pediatric healthcare providers, participate in the US Zika Pregnancy Registry. (cdc.gov)
  • Babies born to women who had the Zika virus infection during pregnancy should be followed up during their first year. (canada.ca)
  • For the duration of the pregnancy, always use condoms correctly or avoid sexual contact with anyone who has travelled to a country or area with risk of Zika virus. (canada.ca)
  • Women should wait 2 months after travel or after onset of illness due to Zika virus (whichever is longer) before trying for a pregnancy, to reduce the risk of passing the virus to the unborn baby. (canada.ca)
  • Men should wait 3 months after travel or after onset of illness due to Zika virus (whichever is longer) before trying for a pregnancy. (canada.ca)
  • To describe the legal abortion at Zika virus infection during pregnancy regarding medical, emotional and social consequences. (bvsalud.org)
  • Authorizing the termination of pregnancy after diagnosis of the virus Zika guarantees women the free exercise of their reproductive rights, which is not confused with state imposition of abortion or eugenic practice. (bvsalud.org)
  • This immune interaction, called antibody-dependent enhancement, could complicate the search for a safe and effective vaccine that protects against Zika without also increasing the risk of dengue. (sciencedaily.com)
  • This interaction, known as antibody-dependent enhancement, could make it harder for researchers to design a safe and effective vaccine that protects against Zika without also increasing the risk of dengue. (sciencedaily.com)
  • That finding raises the questions: Could a vaccine only targeted at Zika actually put people at increased risk of more severe dengue disease? (sciencedaily.com)
  • And how can you design a Zika vaccine that only induces good antibodies that protect you against Zika, but doesn't induce these other, potentially enhancing antibodies that are harmful against disease? (sciencedaily.com)
  • In the new study, researchers led by Genhong Cheng, Ph.D., of the University of California, Los Angeles, investigated whether 25HC has a protective effect against Zika virus, for which there is no licensed antiviral drug or vaccine. (blogspot.com)
  • Because there is no vaccine or medicine for Zika, the virus and its associated health outcomes will remain a significant and enduring public health challenge. (cdc.gov)
  • The first of five early stage clinical trials to test the safety and ability of an investigational Zika vaccine candidate called the Zika Purified Inactivated Virus (ZPIV) vaccine to generate an immune system response has begun at the Walter Reed Army Institute of Research Clinical Trial Center in Silver Spring, Maryland. (news-medical.net)
  • Researchers at the University of North Carolina School of Medicine are conducting studies that utilize blood donations from individuals who have been diagnosed with or potentially exposed to mosquito-borne viruses as part of ongoing dengue and Zika research and vaccine development. (news-medical.net)
  • There is currently no vaccine or medication to prevent Zika virus infection. (cdc.gov)
  • Dr McKimmie said: "One way to do this would be to develop a vaccine that generates neutralising antibodies that bind to these factors, and thereby stop them from working and helping the virus. (leeds.ac.uk)
  • There is currently no specific treatment or effective vaccine for dengue or Zika . (pasteur.fr)
  • The best way to prevent Zika virus infection is to avoid mosquito bites by avoiding exposure and eliminating mosquito breeding areas. (cdc.gov)
  • Effective application of this new approach to multicountry, multiregional events was demonstrated in the response to the outbreak of Zika virus disease. (who.int)
  • At the beginning of the Zika outbreak in South America, my colleagues in Colombia contacted me with concern about the increasing number of patients with neurological complications in their hospitals," says Carlos A. Pardo, M.D., associate professor of neurology and pathology at the Johns Hopkins University School of Medicine, who earned his medical degree in Colombia and is an expert in neuroimmune and infectious diseases, including Guillain-Barré. (hopkinsmedicine.org)
  • The research team, he says, continues to collect clinical data and samples from the Colombian hospitals' patients, but the work is constrained by the limited availability of resources, which is further strained by the severe and ongoing Zika outbreak in South America. (hopkinsmedicine.org)
  • We are pretty sure that there were no strains circulating in South America before 2013 and that the virus has now largely gone" explains Henrik Salje. (medindia.net)
  • The first is that changes may have occurred to the Zika virus - and its transmissibility - when the virus migrated to South America. (medindia.net)
  • Overview of Arbovirus, Arenavirus, and Filovirus Infections Arbovirus (arthropod-borne virus) is defined as any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, mostly insects (flies and mosquitoes). (msdmanuals.com)
  • Although A. aegypti feeds almost exclusively on humans, A. albopictus feeds on humans as well as variety of other animals that are not susceptible to the virus and are not involved in transmission chains. (msdmanuals.com)
  • Serological evidence indicates additional human exposure and/or presence in some mosquito species between 1951 and 1981 in parts of Africa (Uganda and Tanzania having the first detection of antibody in humans, in 1952, followed by isolation of the virus from a young girl in Nigeria in 1954 during an outbreak of jaundice, and experimental infection in a human volunteer in 1956. (wikipedia.org)
  • It is one of the most common human viruses to cause cancer in humans and is associated with a wide range of human cancers originating from epithelial cells, lymphocytes and mesenchymal cells. (marketresearch.com)
  • Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes or ticks, and in the continental United States, West Nile virus (WNV) is the leading cause of domestically acquired arboviral disease. (medscape.com)
  • Zika virus is transmitted to humans by infected mosquitoes which causes mild fever with maculopapular rash. (medindia.net)
  • Unlike humans, viruses do not have a genetic repair system," says Henrik Salje. (medindia.net)
  • Mosquitoes have bedeviled humans for centuries, spreading disease and death to millions. (healthline.com)
  • University of Leeds Virus Host Interaction Team researchers have discovered that the molecule, called sialokinin, makes it easier for a number of viruses to pass from mosquitoes to humans, where they can then take hold - leading to unpleasant and potentially deadly diseases. (leeds.ac.uk)
  • She said: "Our findings may also explain why some mosquitoes can spread infection to humans, while some cannot. (leeds.ac.uk)
  • It is unclear whether this lab virus still behaves in the same way as do Zika viruses currently circulating in Brazilian mosquitoes and infected humans," he said. (the-scientist.com)
  • Mackay added that the iPSC-derived neural cells grown in culture "may not yield infection results that accurately reflect disease processes in humans. (the-scientist.com)
  • That quest led Gong Cheng , a microbiologist at the Tsinghua University-Peking University Joint Center for Life Sciences, to test whether humans infected with dengue fever and Zika virus are more attractive to mosquitos. (smithsonianmag.com)
  • While previous studies had found evidence of increased mosquito attraction in humans infected with mosquito-borne diseases, this study is one of the first to clearly identify a specific chemical as the reason for this attraction. (smithsonianmag.com)
  • The Zika virus was identified in 1947 in Rhesus monkeys in the Republic of Uganda and isolated in humans in 1952 in the same country. (bvsalud.org)
  • When Zika first emerged in Latin America in late 2015, many speculated whether the flavivirus, a close cousin to the dengue viruses, might interact with the dengue viruses in a similar way. (sciencedaily.com)
  • Zika virus is a mosquito-borne flavivirus that was first identified in Uganda in 1947 ( 1 ). (cdc.gov)
  • A bioinformatics analysis performed previously at JCVI uncovered regions of Flavivirus proteins that differentiate between 10 species of viruses-including Zika. (jcvi.org)
  • The flavivirus genus includes several mosquito-transmitted viruses, such as dengue, Japanese encephalitis (JEV) and West Nile virus (WNV). (nottingham.ac.uk)
  • Although most of the flaviviruses are exotic to the UK, louping ill virus is a tick-transmitted flavivirus found in the UK. (nottingham.ac.uk)
  • To determine what specific chemical compound changes with flavivirus infection, the scientists isolated chemicals that were released into the air by infected and uninfected mice. (smithsonianmag.com)
  • The best method for preventing Zika virus infection is to avoid travel to areas with active Zika virus transmission. (medscape.com)
  • Ecuador is one of 26 countries in the Americas that has reported active Zika virus transmission, according to the U.S. Centers for Disease Control and Prevention. (nsf.gov)
  • Epidemiological data has long suggested a close relationship between rising Zika virus infection rates and instances of Guillain-Barré. (hopkinsmedicine.org)
  • Epidemiological and ecological determinants of Zika virus transmission in an urban setting. (springer.com)
  • and/or CDC Zika virus epidemiological criteria, such as a history of residence in or travel to a geographic region with active Zika transmission at the time of travel. (genomeweb.com)
  • Getting sick with one type of dengue virus can increase the likelihood that a person will develop a second, more severe illness when infected with a separate type of dengue virus. (sciencedaily.com)
  • Most infections have no symptoms or cause a mild illness. (europa.eu)
  • Because arboviral diseases continue to cause serious illness, maintaining surveillance programs to monitor their transmission and prevalence is important to the direction and promotion of prevention activities. (medscape.com)
  • [5] Zika virus causes an illness that is like a mild form of dengue fever . (wikipedia.org)
  • Since mosquitoes fly, they can also spread a disease more quickly than an illness such as Ebola, which is transmitted from person to person. (healthline.com)
  • Patients infected with arboviruses such as Zika virus should be advised to limit activity during symptomatic illness in order to avoid exposure to mosquitoes and potential risk for human-to-arthropod transmission and subsequent local spread of disease. (medscape.com)
  • Brown recluse spiders are extremely poisonous, and their bug bites can cause infection and illness. (rxlist.com)
  • New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases, resulting in prolonged illness, disability, and even death. (who.int)
  • In her career at CDC, she has focused on the development of evidence-based clinical guidelines for infectious diseases. (cdc.gov)
  • Almost all patients displayed two or more clinical symptoms of Zika infection, which include fever, headache, rash and conjunctivitis. (hopkinsmedicine.org)
  • 25HC-treated mice were more likely to survive Zika infection, and the surviving mice had no clinical symptoms. (blogspot.com)
  • Three different single-nucleotide polymorphisms (SNPs) in human TLR-7 (rs179010, rs5741880, rs3853839) and 1 SNP in TLR-8 (rs3764879) were associated with increased susceptibility to infection and related clinical manifestations. (medscape.com)
  • For clinical laboratory use, ZeptoMetrix has treated Zika Virus with its proprietary NATtrol™ inactivation process to manufacture non-infectious, molecular testing controls and an assay range validation panel. (prweb.com)
  • Much less attention has been placed on characterizing the biological events associated with the clinical resolution of severe COVID-19, even though understanding disease resolution at the molecular and cellular level might contribute new targets of therapeutic interventions against severe COVID-19. (frontiersin.org)
  • But, says Dr. Benjamin Pinsky , a clinical pathologist at Stanford University Medical Center, the results are "pretty good evidence" that the athletes and staff weren't exposed to Zika virus. (wvxu.org)
  • Additionally, emergency providers learned key nursing assessment, clinical interventions, and the general process for reporting Zika cases. (cdc.gov)
  • Previously only 14 cases of Zika fever had been documented since the virus had first been identified in 1947. (wikipedia.org)
  • The virus is named after the Zika (or Ziika) Forest (near Lake Victoria) in Uganda, as the virus was first isolated in a monkey at this location in 1947 6 . (radiopaedia.org)
  • Zika virus is named after Uganda 's Zika Forest , where the virus was discovered in 1947. (wikipedia.org)
  • In 1947, the virus was first isolated from a rhesus monkey found in the Zika forest of Uganda," he said. (healthline.com)
  • The February 2018 issue of the MSMR contained the results of the most recent, broad surveillance study of the most concerning vector-borne diseases. (health.mil)
  • RIG-I Recognizes the 5' Region of Dengue and Zika Virus Genomes, Cell Reports , July 10, 2018. (pasteur.fr)
  • Zika virus disease and congenital Zika virus infection interim case definition and addition to the nationally notifiable diseases list. (cdc.gov)
  • Data reported to ArboNET using the national surveillance case definition for congenital Zika virus disease or infection (CSTE Position Statement 16-ID-01). (cdc.gov)
  • Intracranial calcifications resulting from congenital Zika virus infections are typically more florid than caused by the TORCH infections and also characteristically at the grey-white matter interface, which is unusual for other congenital viral diseases. (radiopaedia.org)
  • The key thing that our study establishes is that prior Zika infection does significantly increase your risk of both symptomatic and more severe forms of dengue disease," said study first author Leah Katzelnick, who performed the research as postdoctoral scholar at the University of California, Berkeley's School of Public Health. (sciencedaily.com)
  • I wonder if previous infection with Zika is pushing people into symptomatic disease? (sciencedaily.com)
  • By mid-autumn, the researchers had enough evidence to prove that having a prior Zika infection made a person more likely to have a symptomatic dengue infection. (sciencedaily.com)
  • Symptomatic disease generally is mild and characterized by acute onset of fever, maculopapular rash, arthralgia, or nonpurulent conjunctivitis. (cdc.gov)
  • Eleven cases of Zika have been confirmed this year in the Houston area alone, although none of these were locally transmitted, and Florida has reported 33 symptomatic cases . (salon.com)
  • The meeting concluded with agreement on a set of recommendations for urgent implementation in order to keep the Region free from the threat of Zika virus infection. (who.int)
  • The current findings reemphasize that the threat to service members from vector-borne diseases will vary according to the prevalent endemic diseases of specific geographic locations, the availability of protective vaccines, and the implementation of individual and group preventive measures. (health.mil)
  • The pages of the MSMR reflect over 25 years of surveillance studies to inform military leaders and preventive medicine/public health assets about the incidence of vector-borne diseases and appropriate steps to counter the associated threat. (health.mil)
  • The emergence of Zika virus as a global health security threat: a review and a consensus statement of the INDUSEM joint working group (JWG). (springer.com)
  • Zika: The virus has emerged as a major public health threat that's rapidly spreading through South and Central America and the Caribbean. (nsf.gov)
  • "Mosquito saliva enhances virus infection through sialokinin-dependent vascular leakage" is published in PNAS journal on 8 June 2022, 8pm UK time. (leeds.ac.uk)
  • But he cautions that although the study demonstrates a biological and viral association between Zika infection and Guillain-Barré, it does not reveal the biological mechanisms through which Zika might initiate an immune attack on the nerves. (hopkinsmedicine.org)
  • Seventeen patients tested positive for Zika virus in their urine. (hopkinsmedicine.org)
  • Women aged 40-79 years with suspected cases were more likely to test positive for Zika virus infection than those in males in the same age group. (cdc.gov)
  • Health care providers should contact their state or local health department about testing patients with symptoms of Zika virus infection and a compatible travel history. (cdc.gov)
  • The first question was, 'How will prior dengue virus infection affect Zika? (sciencedaily.com)
  • Using data from the cohort, Harris published a 2019 study showing that prior dengue virus infection can grant a small amount of protection against Zika, and other studies now support this conclusion. (sciencedaily.com)
  • Another 18 had no evidence of Zika virus in urine but showed the immunologic footprints of Zika infection through the presence of virus-specific antibodies in their blood or spinal fluid. (hopkinsmedicine.org)
  • Monkeys given 25HC also had reduced levels of Zika virus in blood and urine and did not develop a fever in response to infection. (blogspot.com)
  • Treatment with 25HC significantly decreased levels of Zika virus in fetal mouse brain tissue and greatly reduced the occurrence and severity of developmental defects, including small fetal brain size. (blogspot.com)
  • The two main problems with this virus are that, occasionally, it can lead to neurological complications, such as Guillain-Barr syndrome, or severe fetal brain developmental defects. (medindia.net)
  • Guillain-Barré, which affects an estimated one or two out of 100,000 people after infections, is diagnosed with electrodiagnostic neurological tests that measure the conductive speed and activity of nerve signals. (hopkinsmedicine.org)
  • For the new study, Pardo's team designed strategies with colleagues in Colombia to evaluate patients with suspected neurological problems associated with Zika and provided tools for viral tests of blood, cerebrospinal fluid and urine samples from 68 people with symptoms of Guillain-Barré. (hopkinsmedicine.org)
  • HEV infection is associated with a number of extrahepatic manifestations, including a range of neurological injuries. (nature.com)
  • Researchers believe that this will make it easier for the virus to disperse into other regions of Brazil. (fapesp.br)
  • Subsequent genetic analysis of Brazilian Zika genomes suggest that virus may have been circulating undetected for over 1 year in Brazil. (wikipedia.org)
  • In December, the Ministry of Health estimated that 440,000-1,300,000 suspected cases of Zika virus disease had occurred in Brazil in 2015 ( 5 ). (cdc.gov)
  • Zika virus replication in the mosquito Culex quinquefasciatus in Brazil. (springer.com)
  • Guillain-Barre syndrome after Zika virus infection in Brazil. (springer.com)
  • The still poorly understood Zika virus outbreak across Brazil took a turn in the wrong direction this week. (thedailybeast.com)
  • Since Zika was first reported in Brazil in 2015, cases have exploded in 24 countries or territories. (healthline.com)
  • Shortly after the recent Zika virus outbreak emerged in eastern Brazil, Dr. Richard Scheuermann and his bioinformatics team at JCVI collaborated with software engineers at Northrop Grumman to develop a custom Zika website portal to provide genomic sequence and other data about Zika virus through the public Virus Pathogen Resource (ViPR). (jcvi.org)
  • Within the continental United States, West Nile virus (WNV) is the leading cause of domestically acquired disease caused by arthropod-borne viruses (arboviruses). (medscape.com)
  • In addition to the rise in temperatures and the changes in rainfall patterns, which favor the proliferation of disease-transmitting mosquitoes, the WHO mentioned a few other reasons for the increase in the incidence of arboviruses worldwide: the acceleration of urbanization, which is associated with basic sanitation problems, and the fact that people are out and about again, travelling around locally and internationally now that COVID-19 restrictions have been lifted. (medscape.com)
  • Viruses spread by mosquitoes are known as arboviruses. (leeds.ac.uk)
  • She has 5 years of subject matter expertise in applied epidemiology in arboviral disease surveillance. (cdc.gov)
  • Epidemiology of Zika virus infection. (springer.com)
  • In a collaborative effort with scientists at six Colombian hospitals, Johns Hopkins Medicine researchers report what they believe to be the strongest biological evidence to date linking Zika virus infection and Guillain-Barré syndrome. (hopkinsmedicine.org)
  • Researchers, led by scientists at the University of Colorado School of Medicine, have found basic molecular processes used by the Zika virus to "hijack" the cells that it infects and potentially how it makes molecules that are directly linked to disease. (news-medical.net)
  • Scientists have identified a new "multicomponent" virus -- one containing different segments of genetic material in separate particles -- that can infect animals, according to research published today in the journal Cell Host & Microbe. (news-medical.net)
  • In an attempt to shed light on Zika circulation, scientists from the Institut Pasteur and the CNRS, in collaboration with US teams and the Thai National Institute of Health, decided to investigate the history of the Zika virus in Thailand. (medindia.net)
  • Over the next two years, a total of 1,717 samples were collected, and 368 individuals were revealed to be infected by Zika, giving the scientists the material they needed to start their investigation. (medindia.net)
  • By producing a phylogenetic tree of the Zika virus in Thailand, the scientists discovered that the viral strains within Thailand were genetically very different from each other, and their ancestor seems to have appeared in the country in 2002. (medindia.net)
  • Scientists know that people in Africa and Asia have been getting Zika fever since the 1950s. (wikipedia.org)
  • During CDC's emergency response to the Zika virus disease (Zika) outbreak, geospatial scientists used geographic information systems (GIS) to identify the most affected areas to target public health interventions. (cdc.gov)
  • Partnering with scientists at Florida State University who study Zika virus, Ming's team inoculated the neural progenitors as well as human iPSCs, embryonic stem cells and immature neurons and compared the extent of the resulting infections. (the-scientist.com)
  • By investigating two of these receptors during infection by dengue and Zika viruses, scientists from the Institut Pasteur discovered that a precise region of the viral genome was recognized by a receptor known as RIG-I. Their discovery paves the way for the future development of vaccines for these diseases. (pasteur.fr)
  • Scientists funded by the National Science Foundation (NSF) Ecology and Evolution of Infectious Diseases (EEID) program are looking for answers in three places in Ecuador. (nsf.gov)
  • Scientists studying such diseases are now investigating whether viruses could tweak human physiology to their benefit, and if so, how they do it. (smithsonianmag.com)
  • The scientists concluded that virus infection changes a mouse's odor, making it more attractive to mosquitoes. (smithsonianmag.com)
  • As infections reached their peak, a group of scientists called for the games to be moved somewhere else. (wvxu.org)
  • The first confirmed case of Zika fever in a human occurs in Uganda during 1964 in a field researcher, who experiences a mild, non-itchy rash. (wikipedia.org)
  • Zika fever often causes no symptoms , or only mild symptoms. (wikipedia.org)
  • For most healthy adults, the infection is mild and only one in five people who are infected will become ill. (sdaho.org)
  • Although in most cases, Zika and its relatives only cause mild disease, in a proportion of individuals, infection results in more severe disease, such as encephalitis. (nottingham.ac.uk)
  • Until recently, Zika virus infections had been regarded as relatively mild causing joint pain and fever. (reason.com)
  • Hypothesis-based studies designed to understand the impact of Zika virus infection on the developing immune system, including characterization of immune responses to childhood vaccines post-Zika virus infection are encouraged. (nih.gov)
  • Many viral and bacterial infections may trigger the disease, as well as several vaccines. (thedailybeast.com)
  • There are no specific FDA-approved treatment options or vaccines for treatment and prevention of Zika virus infection. (medscape.com)
  • A new study finds that people who have antibodies to the mosquito-borne Zika virus are more vulnerable to developing dengue disease. (sciencedaily.com)
  • Its findings confirm earlier suspicions that some antibodies to the Zika virus, which usually serve to protect the body from infection, may actually interact with dengue viruses in ways that can make dengue infection worse. (sciencedaily.com)
  • because everyone in Latin America, to some degree or another, is eventually dengue immune and has dengue antibodies," said study senior author Eva Harris, a professor of infectious diseases and vaccinology at UC Berkeley. (sciencedaily.com)
  • Since 2004, Harris and her colleagues in Nicaragua have monitored a cohort of approximately 3,800 children living in Managua, the country's capital, tracking any signs of dengue disease and collecting annual blood samples to test for the virus and its antibodies. (sciencedaily.com)
  • But the inverse question, whether Zika antibodies protect against future dengue disease, or potentially enhance it, remained a mystery. (sciencedaily.com)
  • Brett Pickett recently received funding from the US Agency for International Development (USAID) to develop a method for detecting antibodies against Zika virus in human patients. (jcvi.org)
  • Antibodies show that a person's immune system has fought off a virus. (wvxu.org)
  • The viruses are so closely related that antibodies for one can look a lot like antibodies for another, yielding false positives and sometimes false negatives. (wvxu.org)
  • But because antibodies against the virus can be so similar, he says, "we're unable to say which ones. (wvxu.org)
  • Getting sick with the mosquito-borne Zika virus makes people more vulnerable to developing dengue disease later on, and to suffering from more severe symptoms when they do get sick from dengue, finds a new study published online today (Thursday, Aug. 27) in the journal Science . (sciencedaily.com)
  • These terms refer to the "stooped-over posture" exhibited by individuals with the disease as a consequence of severe chronic incapacitating arthralgias. (medscape.com)
  • Hence, severe or chronic infections could be attributed to an absence or deregulation of 1 of these pathways. (medscape.com)
  • It can bring about significant inflammation and, in some people, severe acute disease. (medscape.com)
  • Longitudinal unbiased proteomic analysis of plasma and single-cell transcriptomics of peripheral blood cells conducted prior to and at multiple times after convalescent plasma transfusion identified the key biological processes associated with the transition from severe disease to disease-free state. (frontiersin.org)
  • Our research suggests that blocking sialokinin may be an exciting new approach that prevents severe disease following infection with numerous distinct viruses. (leeds.ac.uk)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The U.S. Armed Forces and the Department of Defense (DOD) have traditionally dedicated considerable effort to the prevention and treatment of vector-borne diseases that may adversely affect the ability of military service members to train for and execute their operational mission. (health.mil)
  • I'm Loretta Jackson Brown and I'm representing the Clinician Outreach and Communication Activity - COCA - with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
  • Dr. Dana Meaney-Delman is a senior medical advisor in the National Center for Emerging and Zoonotic Infectious Diseases at the Centers for Disease Control and Prevention. (cdc.gov)
  • Saving Lives, Protecting People Centers for Disease Control and Prevention. (cdc.gov)
  • The Programme was established and designed to manage WHO's work in the prevention of, preparedness for, response to and early recovery from emergencies, regardless of the hazard, including infectious diseases, natural disasters and societal conflicts. (who.int)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • These response efforts supported CDC in tracing the virus in real time and displaying outbreak data over time to identify the most affected areas to target public health intervention, informing decision-makers, and spreading prevention awareness to community members. (cdc.gov)
  • While crucial mosquito research is under way in university labs, the U.S. Centers for Disease Control and Prevention (CDC) is also engaged in the global war against life-threatening diseases. (healthline.com)
  • The infection was confirmed by the Centers for Disease Control and Prevention (CDC). (sdaho.org)
  • The World Organisation for Animal Health (OIE) and European Center for Disease Control and Prevention (ECDC) for their contribution of experts and expertise. (who.int)
  • d Division of Global Health Protection, Centers for Disease Control and Prevention, Atlanta, GA. e Arctic Investigation Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK. (who.int)
  • The findings and conclusions in this article are those of the authors and do not necessarily represent the official positions of the United States Centers for Disease Control and Prevention. (who.int)
  • Zika virus footprints tracked to Guillain-Barré syndrome. (hopkinsmedicine.org)
  • Biological tests support association of Zika and Guillain-Barré syndrome. (hopkinsmedicine.org)
  • Guillain-Barre syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. (springer.com)
  • Guillain-Barré syndrome associated with Zika virus infection. (springer.com)
  • Middle East respiratory syndrome coronavirus (MERS-CoV), Ebola virus disease and Zika virus disease. (who.int)
  • Use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with unconfirmed Zika virus infection should be avoided since the use of such drugs in dengue fever is associated with hemorrhagic risk and risk for Reye syndrome in the pediatric population. (medscape.com)
  • A multidisciplinary team approach is recommended while caring for infants with congenital Zika syndrome. (medscape.com)
  • During this COCA Call, emergency providers learned critical information about Zika, such as how to identify people at risk for infection either through recent travel or through sex with someone infected with Zika, examine the importance of screening protocols, and understand likely symptoms, such as fever, rash, joint pain, and conjunctivitis. (cdc.gov)
  • Zika virus transmission worldwide-9 April 2019. (radiopaedia.org)
  • According to the World Health Organisation , 5.2 million people contracted the disease in 2019. (leeds.ac.uk)
  • The 2019 annual tables exclude cases of nationally notifiable conditions and diseases among non-U.S. residents. (cdc.gov)
  • Since Houston and Miami are both large international hubs, it is possible for almost any vector-borne disease to be introduced by travelers. (salon.com)
  • For Pinsky, the takeaway was that despite all the precautions people took to protect themselves against Zika, people still got bitten by mosquitoes. (wvxu.org)
  • Take special precautions to avoid infection with Zika virus. (canada.ca)
  • And they had been advised to wear long sleeves, to use repellent and to not spend time outside at dawn and dusk, when the mosquitoes that carry the viruses are most active. (wvxu.org)
  • The findings of the study are published in The Lancet Infectious Diseases journal. (medindia.net)
  • For one thing, he said, the virus strain used in the study differs to the one responsible for the ongoing outbreak in Latin America. (the-scientist.com)
  • These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). (cdc.gov)
  • We noticed that from the very beginning of the surveillance campaign, Zika could be found all over Thailand," explains Henrik Salje. (medindia.net)
  • Autochthonous hepatitis E in Southwest England: natural history, complications and seasonal variation, and hepatitis E virus IgG seroprevalence in blood donors, the elderly and patients with chronic liver disease. (nature.com)
  • This indicated a potential risk of transmission of the Zika virus through blood transfusions, but there were no confirmed cases of this occurring. (wikipedia.org)
  • People who need blood transfusions may already be very sick, and contracting a contagious disease could kill them. (medicalnewstoday.com)
  • Forty-nine states and the District of Columbia reported 3,035 cases of domestic arboviral disease, including those caused by West Nile (2,911), La Crosse (40), Jamestown Canyon (32), Powassan (24), St. Louis encephalitis (17), unspecified California serogroup (six), and eastern equine encephalitis (five) viruses. (medscape.com)
  • Health care providers should consider arboviral infections in the differential diagnosis of aseptic meningitis and encephalitis, obtain appropriate specimens for laboratory testing, and promptly report cases to public health authorities. (medscape.com)
  • Cheng writes in an email that his team's findings could "inform real-world public health strategies for controlling mosquito-borne flaviviral viral diseases such as dengue and Zika. (smithsonianmag.com)
  • Zika is generally found in mosquitoes and monkeys in a band of countries stretching across equatorial Africa) and Asia (Malaysia, Philippines, Thailand, Vietnam, and Indonesia). (wikipedia.org)
  • Before 2007, only sporadic human disease cases were reported from countries in Africa and Asia. (cdc.gov)
  • Hepatitis E is hyperendemic in many developing countries in Asia and Africa, and is caused by hepatitis E virus (HEV) genotypes 1 and 2, which are spread via the faecal-oral route by contaminated water. (nature.com)
  • Zika was once isolated to Africa and Asia, however, it spread to the Americas in the last decade 1 . (radiopaedia.org)
  • Peterson told Healthline that the Zika virus was discovered in the mid-20th century in Africa. (healthline.com)
  • Zika virus is found in parts of South and Central America, the Caribbean, the Pacific islands, Africa and Asia. (leeds.ac.uk)
  • Zika virus disease is a mosquito-borne disease caused by Zika virus. (europa.eu)
  • The goal of aerial spraying is to reduce the mosquito burden to prevent mosquito-borne disease and to also to allow recovery work to move forward. (salon.com)
  • The Ecuador towns where the EEID researchers are working -- Machala, Huaquillas, and Portovuelo/Zaruma -- vary in climate, elevation and socioeconomic conditions, and in their amount of mosquito-borne disease. (nsf.gov)
  • 1,000 cases reported during the preceding year], United States) of the MMWR Weekly Notifiable Diseases and Mortality Tables, because the condition was not considered nationally notifiable at that time. (cdc.gov)
  • The Zika virus disease data in Table I do not include data from the U.S. Territories, where most of the Zika virus disease cases are currently occurring. (cdc.gov)
  • Lyme disease and malaria were the most common diagnoses among confirmed cases. (health.mil)
  • Among the 1,068 RMEs for vector-borne diseases (confirmed, probable, and suspected), there were only 105 such cases that could be linked to a record of hospitalization for the same diagnosis. (health.mil)
  • The outbreak abated in October 2014, with 8,723 suspected cases of Zika reported. (wikipedia.org)
  • The true number of Zika cases was estimated at more than 30,000. (wikipedia.org)
  • New Caledonia In January 2014, indigenous cases of Zika virus infection were reported in New Caledonia. (wikipedia.org)
  • The outbreak ended on 29 May, with 50 confirmed and 932 suspected cases of Zika virus infection. (wikipedia.org)
  • Easter Island In March 2014, there were one confirmed and 40 suspected cases of Zika virus infection on Easter Island. (wikipedia.org)
  • Solomon Islands An outbreak of Zika begins on the Solomon Islands, with 302 cases reported by 3 May. (wikipedia.org)
  • it is not known how many of these cases are associated with Zika virus infection. (cdc.gov)
  • These imported cases might result in local human-to-mosquito-to-human spread of the virus in limited areas of the continental United States that have the appropriate mosquito vectors. (cdc.gov)
  • Among the WNV disease cases, 2,008 (69%) were classified as neuroinvasive disease, for a national incidence of 0.61 cases per 100,000 population. (medscape.com)
  • Six unspecified California serogroup virus cases were also reported. (medscape.com)
  • Among the 42 West Nile virus disease cases with AFP, 12 (29%) also had encephalitis or meningitis. (medscape.com)
  • And second, the healthcare systems weren't prepared to deal with the complexities that came with such a striking increase in the number of cases of these diseases. (medscape.com)
  • To date, 115 countries have reported cases of the disease, which can cause chronic disabilities and have a major impact on quality of life. (medscape.com)
  • Of these three diseases, Zika accounts for the smallest number of cases. (medscape.com)
  • Before 2007, at least 14 cases of human Zika virus disease had been documented in the literature, although other cases were likely to have occurred and were not published. (healthline.com)
  • In most cases, a tick-an insect about 3 to 5 mm long-must be attached 36-48 hours to spread Lyme disease. (rxlist.com)
  • Since 2007, 39 countries have reported cases of Zika, according to the World Health Organization. (nsf.gov)
  • Up to 2007 there were few cases of human infection in African and Asian countries. (bvsalud.org)