• Below are some important considerations that narcolepsy patients with excessive daytime sleepiness and cataplexy can refer to when speaking with their doctor about their sodium intake, which is a modifiable risk factor for heart health. (newsdaytonabeach.com)
  • Oxybate-containing medications are a treatment option for people with narcolepsy who have excessive daytime sleepiness and cataplexy. (newsdaytonabeach.com)
  • I would definitely recommend to others who are struggling with excessive daytime sleepiness and cataplexy in narcolepsy to talk to their doctor about trying XYWAV to see if it may help them like it helped me," Grace says. (newsdaytonabeach.com)
  • A number of therapies from a range of drug classes are available to address the symptoms of narcolepsy, which include excessive daytime sleepiness and cataplexy. (clarivate.com)
  • The primary endpoint was the change in the weekly number of cataplexy attacks, and the key secondary endpoint was the change in the Epworth Sleepiness Scale (ESS) score with JZP-258 compared to placebo. (sleepreviewmag.com)
  • Positive data from the Phase 3 study of Jazz Pharmaceuticals plc's investigational medicine, JZP-258, for the treatment of cataplexy and excessive daytime sleepiness (EDS) in adults with narcolepsy were presented at World Sleep 2019 in Vancouver, Canada. (sleepreviewmag.com)
  • We are pleased with the positive results from the Phase 3 study of JZP-258, which demonstrate the efficacy of JZP-258 for the treatment of cataplexy and excessive daytime sleepiness in narcolepsy," says Jed Black, MD, senior vice president, Sleep and Neuroscience at Jazz Pharmaceuticals and adjunct professor, Stanford University Medical Center, Stanford Center for Sleep Sciences and Medicine, in a release. (sleepreviewmag.com)
  • DUBLIN, SEPTEMBER 25, 2019 - Jazz Pharmaceuticals plc (Nasdaq: JAZZ) announced today that positive data from the Phase 3 study of its investigational medicine, JZP-258, for the treatment of cataplexy and excessive daytime sleepiness (EDS) in adults with narcolepsy were presented at World Sleep 2019 in Vancouver, Canada. (wakeupnarcolepsy.org)
  • Because of the risk of CNS depression, abuse and misuse, XYWAV is available only by prescription, and filled through the central pharmacy in the XYWAV and XYREM REMS. (newsdaytonabeach.com)
  • Now, we've got clinical experience with the drug in terms of transitioning patients from Xyrem to Xywav, the lower sodium moiety. (neurologylive.com)
  • Does XYWAV taste the same as XYREM? (xywav.com)
  • Can I change from XYREM treatment to XYWAV? (xywav.com)
  • Because of the risk of central nervous system (CNS) depression, abuse, and misuse, XYWAV is available only through a restricted distribution program called the XYWAV and XYREM REMS. (xywav.com)
  • Individuals encountering exorbitant tiredness during the day, cataplexy, rest loss of motion, and hypnagogic mind flights are viewed as experiencing narcolepsy. (wbsofts.com)
  • Most recently, the antidepressants Effexor (an SSNRI), and Strattera (an SNRI), are showing excellent results in alleviating cataplexy and reducing other REM symptoms. (narcolepsyafricafoundation.org)
  • Treatment might incorporate energizers, antidepressants, and xyrem. (wbsofts.com)
  • Jazz Pharmaceutical), an oral solution of calcium, magnesium, potassium, and sodium oxybates, for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients 7 years of age or older with narcolepsy. (neurologylive.com)
  • Our Treatment Algorithms research leverages national patient-level claims data to explore the use of key therapies in narcolepsy, such as modafinil, armodafinil, and Xyrem, in both newly diagnosed and recently treated patients. (clarivate.com)
  • Temporary and sudden muscle weakness without loss of consciousness (called cataplexy ), usually brought on by sudden or strong emotions. (adam.com)
  • It's not always strong or positive emotions that cause my cataplexy. (julieflygare.com)
  • Intense emotions like fear and excitement and laughing can also trigger cataplexy. (epainassist.com)
  • Strong emotions like fear or anger, or when you're laughing, may trigger cataplexy. (healthline.com)
  • Strong emotions are what drives cataplexy. (ghostbed.com)
  • Have received an NT1 diagnosis within the past 10 years or are experiencing NT1 symptoms (characterized by cataplexy, or the sudden loss of muscle control and muscle weakness due to strong emotions or actions, like anger or laughter, while remaining conscious). (hypersomniafoundation.org)
  • Cataplexy is a condition that causes a sudden loss of muscle control and muscle tone. (healthline.com)
  • Cataplexy is characterized by episodes of a sudden loss of muscle tone and control. (healthline.com)
  • Cataplexy causes episodes of muscle weakness and loss of muscle tone. (healthline.com)
  • Cataplexy is a condition that causes sudden episodes of a loss of muscle control. (healthline.com)
  • Cataplexy is an episodic loss of muscle function, ranging from slight weakness such as limpness at the neck or knees, sagging facial muscles, weakness at the knees often referred to as "knee buckling", [9] or inability to speak clearly, to a complete body collapse. (sleepdisordersresource.com)
  • The condition of cataplexy which causes sudden loss of muscle tone can affect any of the muscles in the body. (ghostbed.com)
  • This can range from the simple drooping of eyelids (known as partial cataplexy) to a total body collapse. (epainassist.com)
  • Cataplexy can be a side effect of certain medications, but this is rare. (healthline.com)
  • Off-label means the medications are intended to treat symptoms of depression, but they've also been found to relieve symptoms of cataplexy. (healthline.com)
  • Or, you may not come to know that you have cataplexy if your doctor has already prescribed medications to suppress it. (epainassist.com)
  • Cataplexy also has a severe emotional impact on narcoleptics, as it can cause extreme anxiety, fear, and avoidance of people or situations that might elicit an attack. (sleepdisordersresource.com)
  • Cataplexy can be mild, where your head drops, or it can be severe, causing you to collapse. (healthline.com)
  • The drug being promoted by the sales rep was Xyrem, a powerful central nervous system depressant, approved for "narcolepsy patients who experience cataplexy" and "narcolepsy patients with excessive daytimesleepiness. (pharma-mkting.com)
  • I experience minor cataplexy daily - knees buckling, jaw slackening, eyes fluttering or hands trembling. (julieflygare.com)
  • People with type 1 narcolepsy experience cataplexy . (healthline.com)
  • You may experience cataplexy several times a day or only once a year. (healthline.com)
  • Cataplexy can also be a symptom of some genetic conditions or the result of a stroke or brain tumor. (healthline.com)