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  • Toxicity
  • Xenobiotics such as polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), and trichloroethylene (TCE) accumulate in the environment due to their recalcitrant properties and have become an environmental concern due to their toxicity and accumulation. (wikipedia.org)
  • The toxicity of xenobiotics, such as Roundup, Bisphenol-A, and Atrazine, on kidney and liver cells can be prevented and treated by combinations of herbal extracts, especially Dig1 and Dig2. (rainbow.coop)
  • Here we discuss the current evidence for epigenetic mechanisms underlying latent responses to xenobiotics, and the potential for identifying molecular epigenetic changes that are prodromal to overt morphologic or functional toxicity phenotypes. (rsc.org)
  • subset
  • However, it is plausible that a subset of xenobiotic-induced perturbations of somatic tissue or germline epigenomes result in delayed-onset and long-lasting adverse effects, in particular if they occur during critical stages of growth and development. (rsc.org)
  • nutrients
  • In this narrative review, we provide an overview of the demonstrated and potential actions of some selected nutrients, nutraceuticals, and xenobiotics on renal health and function. (mdpi.com)
  • mechanism
  • Another example of a xenobiotic tolerance mechanism is the use of ATP-binding cassette (ABC) transporters, which is largely exhibited in insects. (wikipedia.org)
  • responses
  • Among the topics are understanding resistance and induced responses of insects to xenobiotics and insecticides in the age of "omics" and systems biology, concepts and complexities of population genetics, resistance to pathogens and parasitic invertebrates, the role of landscapes in insect resistance management, a model for prediction and management, and integrated pest management and insect resistance management. (thefreedictionary.com)
  • Pleiotropic xenobiotics can trigger dynamic alterations in mammalian chromatin structure and function but many of these are likely non-adverse and simply reflect short-term changes in DNA transactions underlying normal homeostatic, adaptive and protective cellular responses. (rsc.org)
  • cells
  • Defined Plant Extracts can Protect Human Cells against Combined Xenobiotic Effects. (rainbow.coop)
  • In general, toxicities were reduced if the herbal extracts were applied to the cells before the xenobiotics rather than after. (rainbow.coop)
  • Finally, in phase III, the conjugated xenobiotics may be further processed, before being recognised by efflux transporters and pumped out of cells. (wikipedia.org)
  • Monitoring
  • OBJECTIVE: We tested the utility of redox-sensitive green fluorescent protein (roGFP)-based redox sensors for monitoring real-time intracellular redox changes induced by xenobiotics in toxicological studies. (thefreedictionary.com)
  • biological system
  • The term xenobiotics, however, is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because xenobiotics are understood as substances foreign to an entire biological system, i.e. artificial substances, which did not exist in nature before their synthesis by humans. (wikipedia.org)
  • Study
  • Fellow, West African Postgraduate College of Pharmacists, Member, Pharmaceutical Society of Nigeria (MPSN), Member, Pharmacists Council of Nigeria (PCN), and Member, International Society for the Study of Xenobiotics (ISSX) among others. (thefreedictionary.com)
  • The HRA Meeting is an approved satellite meeting of the International Society for the Study of Xenobiotics. (issx.org)