- Hypoxanthine and xanthine are two of the many bases created through mutagen presence, both of them through deamination (replacement of the amine-group with a carbonyl-group). (wikipedia.org)
- Hypoxanthine is produced from adenine, xanthine from guanine, and uracil results from deamination of cytosine. (wikipedia.org)
- Cd changes several metabolites associated with purine metabolism (xanthine, hypoxanthine, adenosine, uridine, inosine) and related genes, which are associated with elevated urate levels. (bvsalud.org)
- there is an increased excretion of xanthine and hypoxanthine in non-Lesch-Nyhan gout.D. what are the pyrimidines. (euroasfalti.net)
- In Lesch-Nyhan syndrome, the decrease in uric acid is balanced by an increase in xanthine plus hypoxanthine in blood. (euroasfalti.net)
- As for the non-primary purine nucleobases, hypoxanthine , xanthine , and 7-Methylguanine are examples. (biologyonline.com)
- Other sources of xanthine are hypoxanthine (via the enzymatic activity of xanthine oxireductase ) and xanthosine (via purine nucleoside phosphorylase ). (biologyonline.com)
- The presence of mutagens may promote the formation of hypoxanthine and xanthine. (biologyonline.com)
- This drug is an analog of hypoxanthine which inhibits the xanthine oxidase which further decreases the formation of uric acid and increases the excretion of soluble xanthine and hypoxanthine. (gpatindia.com)
- Xanthylic acid is an important metabolic intermediate in the purine metabolism, and is a product or substrate of the enzymes inosine monophosphate dehydrogenase (EC 1.1.1.205), hypoxanthine phosphoribosyltransferase (EC 2.4.2.8), xanthine phosphoribosyltransferase (EC 2.4.2.22), 5'-ribonucleotide phosphohydrolase (EC 3.1.3.5), Ap4A hydrolase (EC 3.6.1.17), nucleoside-triphosphate diphosphatase (EC 3.6.1.19), phosphoribosylamine-glycine ligase (EC 6.3.4.1), and glutamine amidotransferase (EC 6.3.5.2). (ecmdb.ca)
- This polyphenolic compound is known to be a strong anti-oxidant which scavenges reactive oxygen species (ROS) directly or effectively inhibits ROS-generating enzymes ( e.g. xanthine oxidase, lipoxygenase). (rsc.org)
- These are examples of modified cytosine, thymine or uridine. (wikipedia.org)