Wolbachia into aedes aegypti mosquitoes. Medical search. Frequent questions

Wolbachia pipientis is an intracellular inherited bacterium found in arthropods, where it manipulates host reproduction using phenotypes such as cytoplasmic incompatibility (CI), male killing, parthenogenesis and feminization, and can spread rapidly through insect populations [ 1 ]. (biomedcentral.com)
Background: The mosquito Aedes aegypti was recently transinfected with a life-shortening strain of the endosymbiont Wolbachia pipientis (wMelPop) as the first step in developing a biocontrol strategy for dengue virus transmission. (psu.edu)
The endosymbiont Wolbachia pipientis is being released into populations of the mosquito vector of dengue, Zika, chikungunya and yellow fever viruses throughout the tropics. (grantome.com)
aegypti populations is transinfection with Wolbachia pipientis, which naturally infects ~40-52% of insects but not Ae. (geneconvenevi.org)
Researchers at the University of Wisconsin-Madison have confirmed that a benign bacterium called Wolbachia pipientis can completely block transmission of Zika virus in Aedes aegypti , the mosquito species responsible for passing the virus to humans. (scienceblog.com)
Field trials and modelling studies suggest that elimination of dengue transmission may be possible through widespread release of Aedes aegypti mosquitoes infected with the insect bacterium Wolbachia pipientis (wMel strain), in conjunction with routine dengue control activities. (geneconvenevi.org)
Wolbachia pipientis is known to block replication of positive sense RNA viruses. (geneconvenevi.org)
The DNA sequencing of amplicons revealed 100% similarity to Wolbachia pipientis , confirming the specificity of amplification. (biomedcentral.com)
The second technique is to infect mosquitoes in the laboratory with the Wolbachia pipientis bacteria and subsequently release them in the wild. (mosquitoalert.com)

In addition, the increase in insecticide resistance among Anopheles mosquito populations worldwide is of considerable concern 3 . (nature.com)
aegypti with the wMel Wolbachia strain induces cytoplasmic incompatibility (CI), allows infected individuals to invade native populations, and inhibits transmission of medically relevant arboviruses by females. (geneconvenevi.org)
In 2016, Zika virus-capable mosquito populations have been found adapting for persistence in warm temperate climates. (wikipedia.org)
Mosquito populations were monitored during and after releases to determine the levels of Wolbachia and whether it persisted in the local mosquitoes. (mvcac.org)
Wolbachia was found to be stable and established at consistent levels in local mosquito populations in the majority of areas. (mvcac.org)
The researchers tracked the spread of Wolbachia through mosquito populations over two years by trapping and testing them for the bacteria. (ist.ac.at)
This suggests that as long as the introduction sites are large enough, strategic releases can transform urban mosquito populations. (ist.ac.at)
This helps us to design the best strategy for transforming mosquito populations, so that dengue can no longer spread. (ist.ac.at)
Amid concerns about the initial rise in mosquito populations following the release of Wolbachia-infected larvae, the Ministry of Health reassures the community that this is simply a temporary phenomenon. (expresshealthcaremgmt.com)
For decades people have relied on industrial pesticides to beat back mosquito populations and limit the diseases they spread. (usf.edu)
The idea is to introduce modified Aedes aegypti into wild populations. (usf.edu)
The firm raises mosquitoes en masse, genetically modifies them for sterility (though blasting the bugs with X-rays is another way to accomplish this), then introduces them to wild populations. (usf.edu)
When Wolbachia -infected mosquitoes are released into the wild, they infiltrate natural populations and share the bacteria. (usf.edu)
A promising candidate for arbovirus control and prevention relies on replacing arbovirus-susceptible Aedes aegypti populations with mosquitoes that have been colonized by the intracellular bacterium Wolbachia and thus have a reduced capacity to transmit arboviruses. (geneconvenevi.org)
BACKGROUND: Introgression of the bacterial endosymbiont Wolbachia into Aedes aegypti populations is a biocontrol approach being used to reduce arbovirus transmission. (geneconvenevi.org)
However, for the most part, the management of mosquito-borne viral diseases remains reliant on our ability to control mosquito populations and reduce the amount of contact between mosquitoes and humans. (edu.au)
Releasing masses of Wolbachia-infected mosquitoes into the wild might wipe out entire populations of deadly mosquitoes and the diseases they carry. (hindustantimes.com)
Last week an article was published describing a new control strategy that has almost completely eradicated tiger mosquito populations from two small Chinese islands. (mosquitoalert.com)
The study carried out over a period of three years has managed to reduce the populations of tiger mosquitoes by 94% in two small river islands of the Chinese city of Guangzhou. (mosquitoalert.com)
In fact, tiger mosquitoes from wild populations on the islands of Guangzhou are naturally infected with two variants of the bacteria without any effect on the viability of individuals or their offspring. (mosquitoalert.com)
Therefore, the researchers infected a large number of mosquitoes in the laboratory with a third variant of the bacterium that is not found in the populations of the Guangzhou islands. (mosquitoalert.com)

mosquitoes against pathogens is being released into the tropics as a possible means for limiting human infections with dengue, Zika and other viruses transmitted by the mosquito. (grantome.com)
Aedes aegypti, the yellow fever mosquito, is a mosquito that can spread dengue fever, chikungunya, Zika fever, Mayaro and yellow fever viruses, and other disease agents. (wikipedia.org)
To test whether Zika virus has adapted for more efficient transmission by Aedes aegypti mosquitoes, leading to recent urban outbreaks, we fed mosquitoes from Brazil, the Dominican Republic, and the United States artificial blood meals containing 1 of 3 Zika virus strains (Senegal, Cambodia, Mexico) and monitored infection, dissemination, and virus in saliva. (cdc.gov)
mosquitoes appear to be competent vectors of Zika virus in several regions of the Americas. (cdc.gov)
Because no vaccines or antiviral drugs are available ( 11 ), efforts to prevent Zika virus infection focus on controlling mosquito vectors. (cdc.gov)
Historically, Zika virus has been isolated from several Aedes spp. (cdc.gov)
There are not yet any approved Zika virus vaccines or antiviral medications, and ongoing mosquito control strategies have not been adequate to contain the spread of the virus. (scienceblog.com)
Zika virus belongs to the same family as dengue virus and Aliota and Osorio - with co-authors Stephen Penaido at SVM and Ivan Dario Velez, at the Universidad de Antioquia in Medellin, Colombia - asked whether Wolbachia -harboring Aedes aegypti may also be effective against Zika virus. (scienceblog.com)
They were also interested in studying the mechanisms behind Zika virus infection and transmission in mosquitoes. (scienceblog.com)
In the study, the team infected mice with Zika virus originally isolated from a human patient and allowed mosquitoes from Medellin to feed on the mice either two or three days after they were infected. (scienceblog.com)
The mosquitoes were either harboring the same strain of the Wolbachia bacteria (called wMel) used in field studies or were Wolbachia -free and the mice had levels of virus in their blood similar to humans infected with Zika virus. (scienceblog.com)
An additional group of mosquitoes, both wild-type and Wolbachia -infected, was allowed to feed instead from a membrane containing sheep's blood spiked with a high concentration of Zika virus, per other standard laboratory studies. (scienceblog.com)
Four, seven, 10 and 17 days after the mosquitoes fed on Zika-virus-infected blood the researchers tested them for Zika virus infection, assessed whether the virus had disseminated - or spread to other tissues in the mosquito, and examined whether the virus made its way to the mosquito saliva, where it must be present to be transmitted. (scienceblog.com)
They found that mosquitoes carrying Wolbachia were less likely to become infected with Zika virus after feeding on viral blood, and those that were infected were not capable of transmitting the virus in their saliva. (scienceblog.com)
Mosquitoes with Wolbachia were less capable of harboring Zika virus, and though they do get infected with Zika, it is to a lesser extent than wild-type mosquitoes. (scienceblog.com)
Aedes aegypti spreads viruses such as dengue, Zika and chikungunya, and is highly adept at invading new regions around the world. (edu.au)
Studies have also shown the Wolbachia method can be effective in preventing the transmission of Zika, chikungunya, yellow fever and other mosquito-borne illnesses, researchers said. (aljazeera.com)
The w AlbB strain of Wolbachia is also effective for blocking transmission of other viruses including Zika, chikungunya, and yellow fever. (gla.ac.uk)
This capability could be used to enhance ongoing efforts that use Wolbachia to fight dengue fever and Zika virus. (phys.org)
The ability to genetically engineer Wolbachia could lead to inserting genes that cause the bacteria to produce traits that increase the effectiveness of usingWolbachia against dengue and Zika viruses. (phys.org)
A second major current personal research interest is the epidemilogy and control of major mosquito-borne diseases, notably malaria (working with Azra Ghani ) and 'flaviviruses' - a family of viruses which includes dengue, yellow fever and Zika. (imperial.ac.uk)
Here's how they do it: The mosquitoes being produced in this factory carry bacteria called Wolbachia that block them from transmitting dengue and other viruses, such as Zika , chikungunya and yellow fever , to humans. (gatesnotes.com)
A team at University of Texas Austin has developed a new method for identifying whether a mosquito is of the Aedes aegypti species, which is responsible for transmitting Zika, dengue and other deadly diseases. (mongabay.com)
Although portable tools and "biopesticides" such as Wolbachia are currently effective, adaptive dengue and Zika viruses will likely evolve past these tactics just as they have for countless other methods. (mongabay.com)
Tiny, pesky and deadly, Aedes aegypti mosquitoes are super at spreading disease, including dengue, chikungunya and Zika virus. (usf.edu)
Since vaccines aren't readily available for most mosquito-borne illnesses - those developed for chikungunya, dengue and Zika virus are still in the trial stage - we need other tools to fight them. (usf.edu)
Ruiz knew what he was looking for because he is in charge of a newly formed team that spends the summer months traveling around northern Tulare County to combat the invasion of Aedes aegypti , a mosquito capable of infecting humans with the deadly diseases of dengue, chikungunya, yellow fever, and Zika. (physiciansweekly.com)
aegypti) is the major vector that transmits many diseases including dengue, Zika, and filariasis in tropical and subtropical regions. (geneconvenevi.org)
Viruses such as dengue , Zika and chikungunya are responsible for the commonest human mosquito borne diseases and are transmitted between humans by the mosquitoes Aedes aegypti and Aedes albopictus, predominantly in urban environments. (edu.au)
But in the hot, humid regions of the tropics and subtropics, diseases caused by the Aedes aegypti, such as dengue fever, zika virus and chikungunya, kill tens of thousands of people every year. (hindustantimes.com)
A project operated by Verily Life Sciences (VLS) to wipe out mosquitoes that spread diseases such as dengue fever, encephalitis, malaria, Saint Louis Encephalitis, West Nile virus, and Zika, among others, is having success in tests at three sites in California, according to a report in Nature Biotechnology . (heartlanddailynews.com)
MSF, the Honduran Ministry of Health, the World Mosquito Program, and the National Autonomous University of Honduras are partnering with local communities to implement innovative public health strategies to reduce illness from arboviruses such as dengue, zika and chikungunya. (msf-seasia.org)
Viruses transmitted by mosquitoes, such as dengue, chikungunya or Zika, are one of the most important threats to public health . (mosquitoalert.com)

and furthermore that we would expect to see Wolbachia -like genes in species that do not currently harbour Wolbachia but presumably did in the past. (biomedcentral.com)
Both phylogenetic analyses and theory suggest that Wolbachia can be lost over time from host species by a variety of mechanisms [ 10 - 12 ]. (biomedcentral.com)
Mosquito species that belong to the genus Anopheles have the capacity to transmit parasites such as Plasmodium species, which are the agents of malaria. (nature.com)
aegypti's distribution has increased in the past two to three decades worldwide, and it is considered to be among the most widespread mosquito species. (wikipedia.org)
As the world's climate becomes warmer, the range of Aedes aegypti and a hardier species originating in Asia, the tiger mosquito Aedes albopictus, which can expand its range to relatively cooler climates, will inexorably spread north and south. (wikipedia.org)
This was the second mosquito species to have its genome sequenced in full (the first was Anopheles gambiae). (wikipedia.org)
While not typically found in the Aedes aegypti mosquito - the species that also transmits dengue, chikungunya and yellow fever viruses - O'Neill discovered in the early 1990s that Wolbachia could be introduced to the mosquito in the lab and would prevent the mosquitoes from transmitting dengue virus. (scienceblog.com)
That is one of the surprise discoveries made by a pair of Vanderbilt biologists when they sequenced the genome of a virus that attacks Wolbachia, a bacterial parasite that has successfully infected not only black widow spiders but more than half of all arthropod species, which include insects, spiders and crustaceans. (phys.org)
The Wolbachia bacteria exist naturally in about 60% of insect species, just not in the Aedes aegypti mosquito. (whnt.com)
DIY Diagnostics , a team of researchers based at University of Texas at Austin, has been investigating how the Wolbachia bacterium can be used to suppress the load of dangerous viruses transmitted to humans by one of the most notorious mosquito species, Aedes aegypti . (mongabay.com)
Existing vector control tools alone have been unable to sustainably control these mosquito species or the diseases they transmit [ 1 ], and a range of novel technologies are under development [ 2 ]. (biomedcentral.com)
Wolbachia , obligate intracellular bacteria, infect the majority of arthropods, including many mosquito species of medical importance. (biomedcentral.com)
Wolbachia is an intracellular bacterium that naturally infects the majority of insect species [ 7 ]. (biomedcentral.com)
These viruses usually circulate within the wild vertebrate population and may be transmitted by a large number of mosquito species. (edu.au)
Infecting mosquitoes with Wolbachia, which occurs naturally in some mosquito species, is a popular approach rooted in an old insect control strategy called sterile insect technique. (hindustantimes.com)
Instead, Wolbachia is a naturally occurring bacterium in some mosquito species, just not the Aedes aegypti . (heartlanddailynews.com)
Wolbachia is a type of bacteria that can infect many species of invertebrates-organism with no backbone-including mosquitoes such as Aedes aegypti , the mosquito that carries and spreads the dengue viruses. (healthtoday.net)
The tiger mosquito, Aedes albopictus , one of the species capable of transmitting these viruses, has expanded in recent decades throughout the world occupying densely populated urban environments. (mosquitoalert.com)
Wolbachia bacteria are found naturally in many species of insects, some say that more than half of the insects are carriers of this bacterium, being the tiger mosquito among the species normally infected by this bacterium. (mosquitoalert.com)
Wolbachia bacteria live inside mosquito cells , being located mainly in the gonads, is transmitted to the offspring and can affect the reproduction of the species. (mosquitoalert.com)
Dengue outbreaks have also been associated with Aedes albopictus , particularly in China, 3 and several other Aedes species found in South Pacific countries and areas may also be competent dengue vectors. (who.int)
Arbovirus (arthropod-borne virus) is defined as any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, mostly insects (flies and mosquitoes) and arachnids (ticks). (msdmanuals.com)
Dengue virus is transmitted by female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, A. albopictus . (who.int)

For media resources from the World Mosquito Program such as photos, videos, facts, media contacts, or access to our spokespeople. (worldmosquitoprogram.org)
This emerging strategy for battling dengue was pioneered over the last decade by the nonprofit World Mosquito Program, and it is being tested in more than a dozen countries. (mystateline.com)
The study was conducted by the World Mosquito Program at Monash University in Australia and Indonesia's Gadjah Mada University. (aljazeera.com)
This is the result we've been waiting for," said World Mosquito Program director Scott O'Neill. (aljazeera.com)
The World Mosquito Program aims to spread Wolbachia among Aedes aegypti mosquitoes, a tropical mosquito that is a host for dengue, yellow fever, and other viruses. (gatesnotes.com)
The mosquitoes come from eggs, produced in a World Mosquito Program bio factory to carry the bacteria Wolbachia, which interrupts the transmission of dengue. (whnt.com)
The trial was conducted by the World Mosquito Program with its Indonesia partners the Tahija Foundation and Universitas Gadjah Mada. (worldmosquitoprogram.org)

Aedes aegypti can be confused with Aedes albopictus without a magnifying glass: the latter have a white stripe on the top of the mid thorax. (wikipedia.org)
In the early 2000s, a structural change in the virus appears to have allowed it to become more easily transmitted by Aedes albopictus . (edu.au)
This is mainly due to the increase in global trade and passenger movements which spread viraemic people and invasive mosquito vectors such as Aedes aegypti and Aedes albopictus around the world. (edu.au)
The virus and associated mosquitoes - Aedes aegypti and Aedes albopictus, or the yellow fever and Asian tiger mosquitoes - are not only booming in endemic countries, they're also pushing into higher altitudes and latitudes. (channelnewsasia.com)

A bacterium called Wolbachia that ?vaccinates? (grantome.com)
Explore our story timeline, which all started with a bacterium called Wolbachia . (worldmosquitoprogram.org)
The mosquitoes are infected with a naturally-occurring bacterium called wolbachia. (bigpinekey.com)
The insects are bred in Verily labs to be infected with a common bacterium called Wolbachia. (hindustantimes.com)

By examining the fitness of the evolved mosquitoes and of the evolved viruses, we will address the question of whether such variants would be competitive and pose a real threat to evolution in natural environments. (grantome.com)
The introduction of the naturally occurring wMel Wolbachia strain into Aedes aegypti mosquitoes has been shown to reduce the ability of the mosquitoes to transmit dengue and other viruses. (mvcac.org)
Included within the series are papers on orbiviruses transmitted by Culicoides, lesser known viruses transmitted by mosquitoes including Cache Valley, Everglades, Jamestown Canyon, and LaCrosse, and recently discovered viruses transmitted by ticks including Bourbon, Heartland, Colorado tick fever, and Powassan. (mvcac.org)
To find out how we use larvae like these to develop new ways of combatting Aedes aegypti and the viruses it spreads, you can read through posts on this blog or take a look at some of our publications. (edu.au)
Using a strain of the bacteria Wolbachia , which inhibit mosquitoes from transmitting viruses to humans, researchers at the Universities of Glasgow and Melbourne and the Institute for Medical Research in Malaysia were successfully able to reduce cases of dengue at sites in Kuala Lumpur. (gla.ac.uk)
It turns out that Wolbachia prevents these viruses from reproducing in Aedes aegypti mosquitoes that spread them. (phys.org)
Suppression efforts have mainly focused on mosquito control, but an international, non-profit research collaboration, the Eliminate Dengue Program, is trialing a new approach: harnessing bacteria that infect mosquitoes and so reduce their capacity to transmit viruses. (ist.ac.at)
These mosquitoes are allies in the fight against dengue and other deadly viruses. (gatesnotes.com)
Then, they release them across the country to breed with wild mosquitoes that can carry dengue and other viruses threatening to sicken and kill the population of Colombia. (gatesnotes.com)
Scientists have learned that infecting these mosquitoes with Wolbachia stymies their ability to pick up dengue and other viruses. (usf.edu)
In areas where these wild reservoirs are close to humans and mosquito vectors feed on both, these viruses can "spill over" into the human population and present a considerable public health threat. (edu.au)
Many mosquito-borne viruses are classed as "emerging pathogens" because their incidence and geographic range is increasing. (edu.au)
Our researchers currently work on a variety of mosquito borne viruses to better predict and control the threat that they pose to human health. (edu.au)
All of the mosquitoes in the NEA are Aedes aegypti, according to Undark , which is a type that may infect humans with viruses like dengue. (interestingengineering.com)
When the mosquitoes carry Wolbachia , the bacteria compete with viruses like dengue, making it harder for viruses to reproduce inside the mosquitoes. (msf-seasia.org)
This means that mosquitoes are much less likely to spread viruses from person to person, reducing dengue fever in an area where Wolbachia is established in the local mosquito population, " says Claire Dorion, MSF technical adviser. (msf-seasia.org)
As there are no vaccines or effective pharmacological treatments available for most of these viruses, control of vector mosquitoes is the best means to reduce the incidence of these diseases. (mosquitoalert.com)

Aedes aegypti , the most important mosquito vector of human dengue fever and various other arboviruses, is naturally Wolbachia -uninfected but has been shown to be able to support Wolbachia following artificial transinfection - with both high rates of maternal inheritance and the expression of high levels of CI [ 13 ]. (biomedcentral.com)
Globally invasive Aedes aegypti disseminate numerous arboviruses that impact human health. (geneconvenevi.org)
mosquitoes are the main urban vector of other medically important urban arboviruses with similar origins, such as dengue virus (DENV), chikungunya virus (CHIKV), and yellow fever virus. (cdc.gov)
The first site of replication for arboviruses is the mosquito midgut," says Aliota. (scienceblog.com)
aegypti-born arboviruses. (edu.au)
This includes releasing Aedes aegypti mosquitoes carrying the natural Wolbachia bacteria, which reduces mosquitoes' ability to transmit arboviruses. (msf-seasia.org)
Most arboviruses are transmitted by mosquitoes, but some are transmitted by ticks, and one (Oropouche virus) is transmitted by midges. (msdmanuals.com)
Birds are often reservoirs for arboviruses, which are transmitted by mosquitoes to horses, other domestic animals, and humans. (msdmanuals.com)

Martha Ocampo drops a capsule of mosquito eggs into a jar of water as directed by a Doctors Without Borders volunteer, as part of a program to help prevent the spread of dengue, in Tegucigalpa, Honduras, Wednesday, Aug. 23, 2023. (mystateline.com)
Edgard Boquín, a project leader working with Doctors Without Borders, holds a glass jar filled with mosquitoes before their release in neighborhoods rife with dengue, in a facility in Tegucigalpa, Honduras, Tuesday, Aug. 22, 2023. (whnt.com)
In May 2023, Oxitec voluntarily withdrew its research authorization application to test the use of genetically engineered mosquitoes in California. (geneconvenevi.org)

Another indirect method for the estimation of mosquito age is the morphological determination of ovariole dilatation to distinguish whether a female mosquito is nulliparous (has not yet laid eggs), and therefore likely to be young, or parous (has laid eggs), and therefore older 7 . (nature.com)
The white eggs are laid separately into water and not together, unlike most other mosquitoes, and soon turn black. (wikipedia.org)
aegypti is two to four weeks depending on conditions, but the eggs can be viable for over a year in a dry state, which allows the mosquito to re-emerge after a cold winter or dry spell. (wikipedia.org)
Female mosquitoes looking for a place to lay their eggs are attracted to the grass pellet/water mixture. (edu.au)
As Aedes aegypti eggs take a while to hatch into larvae, an ovitrap can be retrieved about a week after deployment with plenty of unhatched eggs stuck to the felt, and the trap can then be quickly redeployed with a fresh felt. (edu.au)
These are the eggs of (likely) Aedes aegypti , and have been laid at the water line. (edu.au)
When a wolbachia-infected male mates with a wild female Aedes aegypti, the resulting eggs do not hatch. (bigpinekey.com)
But mama mosquitoes require blood to mature their eggs. (usf.edu)
Female mosquitoes need a chemical lure to keep them eating until they've had their fill, because they need to engorge themselves in order to produce healthy eggs. (usf.edu)
The mosquitoes can lay eggs in spaces as small as a bottle cap, and females spread their eggs across multiple locations - scientists often refer to their "cryptic habitats. (physiciansweekly.com)
Most other types of mosquito eggs need water to survive, but Aedes aegypti 's can lie dormant for months, springing to life when water eventually does come. (physiciansweekly.com)
Wolbachia is capable of manipulating host reproduction through cytoplasmic incompatibility [ 8 , 9 ], in which Wolbachia -infected eggs form viable offspring and noninfected eggs do not. (biomedcentral.com)
When males mate with local Wolbachia-free females, the females lay eggs that won't hatch, and in time the number of mosquitoes decreases. (interestingengineering.com)
As for how the mosquitoes might be caused to infiltrate a desired area, the researchers note that when infected male mosquitoes mate with uninfected females, the females lay eggs that never hatch. (edu.au)
Male Aedes aegypti infected with Wolbachia will mate with female mosquitoes, but the resulting eggs will not hatch . (healthtoday.net)
When male mosquitoes infested with the third variant mate with wild females that have a different combination, eggs cannot develop and never hatch ( Fig. 1 ). (mosquitoalert.com)
containing dried mosquito eggs have facilitated the vectors' spread. (who.int)

the Cambodia strain was not transmitted by mosquitoes from Brazil after artificial blood meals, whereas 61% transmission occurred after a murine blood meal (saliva titers up to 4 log 10 infectious units/collection). (cdc.gov)
Previously, scientists have carried out successful mosquito releases using a different strain of the Wolbachia bacteria, but while this strain was effective in some conditions, it did not appear to be suitable for use in the very hot conditions experienced in equatorial countries such as Malaysia. (gla.ac.uk)
Now, this international team of researchers has shown that the wAlbB strain of Wolbachia is stable and effective, even in daily peak temperatures of 36 degrees and higher, as commonly experienced in areas of Malaysia where dengue is prevalent. (gla.ac.uk)
Researchers released batches of Aedes aegypti mosquitoes carrying the w AlbB strain of Wolbachia into the wild, in six different sites in greater Kuala Lumpur with high levels of dengue transmission. (gla.ac.uk)
Professor Steven Sinkins, lead contact for the study and Professor at the MRC-University of Glasgow Centre for Virus Research, said: "We are excited by these findings, which show that we have a strain of Wolbachia that can be used to effectively reduce the number of dengue cases in very hot climates. (gla.ac.uk)
It is exciting to see, for the first time, a strain of Wolbachia successfully reduce the number of dengue cases in very hot climates in the wild. (gla.ac.uk)
Previously, we created an Aedes aegypti Aag2 cell line (Aag2.wAlbB) transinfected with the wAlbB strain of Wolbachia and a matching tetracycline-cured Aag2.tet cell line. (geneconvenevi.org)
Hence, identification of native Wolbachia strains in areas where malaria transmission is low may uncover a particular Wolbachia strain capable of Plasmodium interference. (biomedcentral.com)
A team of researchers affiliated with several institutions in Vietnam and Australia has found that introducing a strain of bacteria known to infect mosquitoes in the wild was more effective in reducing dengue infections than bacteria introduced in the lab. (edu.au)
In this new effort, the researchers looked at the possibility of introducing a bacteria strain that infects dengue-carrying mosquitoes, but not in a way that will lead to resistance. (edu.au)
The researchers settled on wMel, a Wolbachia bacteria strain that prior research has shown to be harmless to mosquitoes but reduces their susceptibility to the dengue virus. (edu.au)
The wMel strain of Wolbachia can reduce the permissiveness of Aedes aegypti mosquitoes to disseminated arboviral infections. (edu.au)

and two Wolbachia strains. (biomedcentral.com)
Only mosquitoes from the Dominican Republic transmitted the Cambodia and Mexica strains. (cdc.gov)
Some Wolbachia strains interfere with the development of Plasmodium parasites in female Anopheles , a major vector of malaria. (biomedcentral.com)
This study aims to identify native Wolbachia strains in female Anopheles spp. (biomedcentral.com)
The DNA sequences of the amplicons were phylogenetically compared with those of known Wolbachia strains. (biomedcentral.com)
The phylogenetic trees indicate a close relationship with Wolbachia strains in subgroup B. (biomedcentral.com)

Dengue fever infections dropped dramatically in an Indonesian study where a bacteria was introduced into disease-carrying mosquitoes, offering hope in the battle against an illness that sickens millions annually around the world. (aljazeera.com)

Here we sought to quantify the blood-feeding behaviour of Wolbachia-infected females as an indicator of any virulence or energetic drain associated with Wolbachia infection. (psu.edu)
Conclusions/Significance: Taken together the evidence suggests that wMelPop infection may be causing tissue damage in a manner that intensifies with mosquito age and that leads to reduced blood-feeding success. (psu.edu)
To predict Anopheles drivers of malaria transmission, such as mosquito age, blood feeding and Plasmodium infection, we evaluated artificial neural networks (ANNs) coupled to matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) and analysed the impact on the proteome of laboratory-reared Anopheles stephensi mosquitoes. (nature.com)
ANNs were sensitive to Anopheles proteome changes and specifically recognized spectral patterns associated with mosquito age (0-10 days, 11-20 days and 21-28 days), blood feeding and P. berghei infection, with best prediction accuracies of 73%, 89% and 78%, respectively. (nature.com)
To establish Plasmodium infection rates in mosquitoes, the microscopy observation of salivary glands has been routinely performed in malaria-endemic countries 1 . (nature.com)
This paper examines the effect of larval nutrition on the susceptibility of Wolbachia infected Aedes aegypti mosquitoes to dengue virus infection. (worldmosquitoprogram.org)
They found that Wolbachia infected mosquitoes had significantly reduced dengue virus infection rates across all three diets‚ suggesting that the effectiveness of Wolbachia in disrupting dengue virus infection is unlikely to be compromised by varied larval nutrition in field settings. (worldmosquitoprogram.org)
Our findings indicate that Wolbachia infection of Ae. (geneconvenevi.org)
They have been exposed to a bacteria known as Wolbachia, which they will transmit to the next generation in an effort to halt the deadly viral infection. (interestingengineering.com)
The wMel-infected mosquitoes that are field-reared have even greater relative resistance to DENV infection when fed on patient-derived viremic blood meals. (edu.au)
This is explained by an increased susceptibility of field-reared wild-type mosquitoes to infection than laboratory-reared counterparts. (edu.au)
Dengue is a viral infection transmitted through the bite of infected mosquitoes. (msf-seasia.org)

The below GIF shows some recently-hatched Aedes aegypti larvae in the PEARG lab. (edu.au)
By releasing mosquito larvae infected with Wolbachia into five dengue-endemic cities in Indonesia, the Ministry of Health has initiated a long-term treatment strategy that promises to measurably reduce the burden of dengue. (expresshealthcaremgmt.com)
He grabbed a turkey baster and drew water, already knowing what he would find: the larvae of Aedes aegypti , one of the greatest threats to humans on the planet. (physiciansweekly.com)
Tulare's mosquito control districts have poured extensive resources into that battle, including releasing a range of chemicals, maintaining a hatchery for larvae-eating fish, and, most recently, buying a drone to ferry pesticides deep into cornfields. (physiciansweekly.com)
The use of insecticides targeting larvae and adult mosquitoes remains the mainstay of vector control programmes. (who.int)

Wolbachia can be found in up to 60 percent of insects around the world, including butterflies and bees. (scienceblog.com)
Which explains why a dozen people cheered last month as Tegucigalpa resident Hector Enriquez held a glass jar filled with mosquitoes above his head, and then freed the buzzing insects into the air. (mystateline.com)
Previous trials involving Wolbachia - commonly found in fruit flies and other insects - also showed positive results in reducing dengue cases, researchers said. (aljazeera.com)
This naturally occurring bacterium, commonly found in insects, works its magic by rendering the Aedes aegypti mosquito sterile when present in their bodies. (expresshealthcaremgmt.com)
These include Release of Insects Carrying a Dominant Lethal system and Wolbachia , an endosymbiotic bacterium, to inhibit dengue virus in the vector. (who.int)

This requires mass release of Wolbachia-infected mosquitoes. (geneconvenevi.org)

Mosquitos infected with the bacteria Wolbachia are significantly worse vectors for dengue virus, and are therefore a promising tool in fighting the disease, but how to establish and spread Wolbachia in an urban mosquito population is unclear. (ist.ac.at)
Given that Anopheles mosquitoes are malaria vectors, one of the effective strategies to control malaria transmission relies on the use of insecticides, including indoor residual spraying and the use of insecticide-treated mosquito nets. (biomedcentral.com)
It's not just mosquitos that are enjoying the warmer temperatures, but a whole host of disease-spreading vectors, including ticks (which carry encephalitis and Lyme disease) and even freshwater snails (schistosomiasis). (channelnewsasia.com)

However, the controversial project's strategy aimed to restrict the number of female Aedes aegypti that may spread disease by adding a self-limiting gene that causes offspring to die before reaching adulthood. (interestingengineering.com)

Our method of reducing mosquito-borne diseases is natural and self-sustaining. (worldmosquitoprogram.org)

Scientists have made great strides in recent decades in reducing the threat of mosquito-borne diseases, including malaria. (mystateline.com)
The use of Wolbachia as a means to block malaria transmission is an emerging vector control strategy in highly endemic areas. (biomedcentral.com)
However, a meta-analysis-based model of malaria transmission predicted that insecticide resistance potentially increased malaria incidence in part because of the decrement of mosquito mortality [ 6 ], challenging global malaria eradication. (biomedcentral.com)
Attendees also learned about recent advancements in vaccine and antiviral research for mosquito-borne diseases like Dengue and malaria. (mecohlab.com)
Microsoft Corp co-Founder Bill Gates has pledged more than $1 billion to help wipe out malaria, including controversial efforts to genetically modify mosquitoes. (hindustantimes.com)

Recent transfers of genome fragments from Wolbachia into insect chromosomes have been reported, but it has been argued that these fragments may be on an evolutionary trajectory to degradation and loss. (biomedcentral.com)
We saw reduced vector competence in Aedes aegypti with Wolbachia ," says Osorio, defined as the intrinsic ability of an insect to support the development or replication of a pathogen like a virus and then transmit it. (scienceblog.com)
The low-cost, 3D-printed portable toolbox identifies a pair of genes in a crushed-up mosquito that reveal whether the insect is Aedes aegypti and whether it has been exposed to the Wolbachia bacterium, which prevents the spread of diseases carried by the mosquito. (mongabay.com)
After capturing a mosquito, the user mashes up the insect, which exposes more genetic material, and places the remains within two capsules in the test kit's 3D-printed toolbox. (mongabay.com)
The replacement approach contrasts with suppression strategies with Wolbachia , sterile insect techniques, or conventional vector control tools, which likely need ongoing application. (biomedcentral.com)
Pilot programs of the sterile insect technique (SIT) against Aedes aegypti may rely on importing significant and consistent numbers of high-quality sterile males from a distant mass rearing factory. (geneconvenevi.org)
Wolbachia bacteria reside in the cytoplasmic vacuoles of various types of insect somatic and germ cells, allowing maternal transmission to their progeny. (biomedcentral.com)
With nations in South America battling some of the worst outbreaks of mosquito-borne disease in decades, the case of a British woman who caught dengue while on holiday in France last summer has sparked warnings about similar outbreaks in countries where insect-carried pestilence hasn't previously been endemic. (channelnewsasia.com)
This technique has been useful to combat other insect pests, but in mosquitoes their success has always been limited . (mosquitoalert.com)

The mosquitoes Enriquez unleashed in his El Manchen neighborhood - an area rife with dengue - were bred by scientists to carry bacteria called Wolbachia that interrupt transmission of the disease. (mystateline.com)
Results of the three-year study, published in the New England Journal of Medicine this week, found that infecting dengue-carrying mosquitoes with a harmless bacteria called Wolbachia led to a 77 percent drop in human cases. (aljazeera.com)
Another promising tool is a bacteria called Wolbachia . (channelnewsasia.com)

A: Wolbachia renders mosquitoes that carry the dengue virus sterile, preventing them from transmitting the virus when they bite humans. (expresshealthcaremgmt.com)
The lab-grown bugs can be sterile, which could eventually reduce the total number of mosquitoes. (usf.edu)
When the sterile males mate with the wild females, no offspring are produced, diminishing the total number of mosquitoes. (usf.edu)
The Galapagos Islands will receive 100,000 sterile male mosquitoes as part of a new vector control strategy in Ecuador, the Center for Research in Infectious and Vector Diseases (CIREV) announced. (geneconvenevi.org)
It uses no chemicals or toxins, nor does it require genetically modifying mosquitoes to make them sterile or produce sterile offspring. (heartlanddailynews.com)

Methodology/Principal Findings: In a series of blood-feeding trials in response to humans, we have shown that Wolbachia-infected mosquitoes do not differ in their response time to humans, but that as they age they obtain fewer and smaller blood meals than Wolbachia-uninfected controls. (psu.edu)
These pathogens are transmitted to humans during the blood meal of an infected female Anopheles mosquito 1 . (nature.com)
Wolbachia suppresses the ability of the virus to replicate in dengue-carrying Aedes aegypti mosquitoes and cause infections when they bite humans. (aljazeera.com)
How humans are striking back against mosquitoes. (gatesnotes.com)
As a result, these mosquitoes are unable to transmit the dengue virus to humans, effectively breaking the cycle of transmission. (expresshealthcaremgmt.com)
It's important to note that Wolbachia does not pose any threat to humans-it solely impacts the mosquitoes, making it an environmentally friendly approach that preserves the delicate balance of our ecosystems. (expresshealthcaremgmt.com)
Q: Can humans be infected with Wolbachia bacteria? (expresshealthcaremgmt.com)
Humans are primarily infected through the bite of infected Aedes aegypti . (edu.au)
It is transmitted to humans by mosquitoes such as Culex annulirostris and Aedes vigilax which are abundant across Australia and which commonly bite animals, birds and humans. (edu.au)
Increasing urbanisation, climate change and the encroachment of humans in previously wild habitats with a diverse vertebrate and mosquito fauna also play a role. (edu.au)
Aedes aegypti mosquitos no longer readily transmit the dengue virus to humans when infected with Wolbachia. (interestingengineering.com)
If the mosquitos in a given area are less likely to be infected, the team reasoned, than fewer humans would be infected. (edu.au)
T he World Mosquito Program's Wolbachia method is safe for humans and the environment and has been successfully deployed in more than 12 countries, reaching some 10 million people. (msf-seasia.org)

The selective decrease of feeding success in older mosquitoes may act synergistically with other Wolbachiaassociated traits including life-shortening and viral protection in biocontrol strategies. (psu.edu)
An important feature of Wolbachia is that it is self-sustainable, making it a very low-cost approach for controlling mosquito-borne viral diseases that are affecting many tropical countries around the world. (scienceblog.com)
The unprecedented rise of dengue worldwide make control methods such as these a vital addition to the tools we currently have to tackle one of the fastest-spreading mosquito-borne viral diseases. (gla.ac.uk)
More than 2.5 billion people live in areas afflicted by dengue fever, a mosquito-borne viral disease that is increasing at alarming rates in tropical and subtropical countries. (ist.ac.at)
Many other mosquito borne viral diseases may only occasionally manifest in the human population. (edu.au)
There are currently no cures or preventative treatments available for most mosquito-borne viral diseases. (edu.au)
Dengue is a mosquito-borne viral disease of public health significance that has rapidly spread in all regions of WHO in recent years. (who.int)

Earlier, IE reported that the biotech company Oxitec , backed by Bill Gates, moved forward with plans to release hundreds of millions of genetically engineered mosquitoes in Florida to test a novel population pest control method. (interestingengineering.com)

This toolkit can also determine whether a mosquito has been exposed to the Wolbachia bacteria, which infects mosquitoes and prevents them from transmitting dangerous pathogens. (mongabay.com)
Only female mosquitoes consume blood giving them the opportunity to transmit deadly human pathogens. (geneconvenevi.org)

But to raise a swarm of Aedes aegypti - also known as yellow fever mosquitoes (for one of the diseases they spread) - you need blood. (usf.edu)

A low-cost, portable, and accurate tool like ours, which is easy to use and interpret, will facilitate access to testing and more widespread and/or frequent [mosquito] surveillance, especially in austere settings," Dr. Sanchita Bhadra, lead author of the study, told Mongabay. (mongabay.com)
But Tulare County officials hope the region will soon be a testing ground for a new generation of technology, including a genetically modified mosquito, as they try to prevent the kind of disease outbreaks now common in regions of the Caribbean and Central and South America where Aedes aegypti is widespread. (physiciansweekly.com)

In Honduras, where 10,000 people are known to be sickened by dengue each year, Doctors Without Borders is partnering with the mosquito program over the next six months to release close to 9 million mosquitoes carrying the Wolbachia bacteria. (mystateline.com)
This factory breeds 30 million mosquitoes per week. (gatesnotes.com)
Last year, Verily released about 14.4 million mosquitoes in Fresno County. (hindustantimes.com)

Q: How does Wolbachia reduce dengue transmission? (expresshealthcaremgmt.com)

Researchers led by Jorge Osorio, a UW-Madison professor of pathobiological sciences, and Scott O'Neill of the the Eliminate Dengue Program (EDP) and Monash University in Melbourne, Australia, are already releasing mosquitoes harboring the Wolbachia bacterium in pilot studies in Colombia, Brazil, Australia, Vietnam and Indonesia to help control the spread of dengue virus. (scienceblog.com)
Infections requiring hospitalisation also fell by 86 percent in Wolbachia-treated areas of Yogyakarta, a city on Java island where the experiment was conducted, researchers said. (aljazeera.com)
The researchers released adult Aedes aegypti mosquitoes infected with Wolbachia bacteria in three areas near to suitable mosquito habitat in Cairns, Queensland. (ist.ac.at)
The researchers found that Wolbachia-infected mosquitoes spread at about 100-200 meters per year in the larger sites, but there was little evidence of such spread in the smaller area even after two years. (ist.ac.at)
However, the researchers also found that spread could be impeded by barriers to mosquito movement, which could include roads, rivers and forests. (ist.ac.at)
Biologist Immo Hansen and his team of researchers at New Mexico State University have come up with a solution: a diet for mosquitoes that would mean fewer animals having to be milked for their blood. (usf.edu)
After checking its mosquito traps each night, the researchers concluded Wolbachia-infected males successfully suppressed more than 95 percent of the female mosquito population in the areas surrounding the test sites. (heartlanddailynews.com)
NEA researchers in Singapore have released male mosquitoes carrying the Wolbachia parasite since 2016. (interestingengineering.com)
A new paper published by researchers from the Doherty Institute and other collaborators in Australia and Vietnam has found that a bacteria used to slow the spread of dengue virus in mosquitoes works better in wild than in the lab. (edu.au)
The researchers were unable to explain the difference, but suggest it might be due to a different mosquito diet. (edu.au)

Since 2017, the company has released millions of lab-bred Aedes aegypti male mosquitoes into several Fresno County neighborhoods during mosquito season. (hindustantimes.com)
Mosquito Mate began releasing lab-bred Aedes aegypti male mosquitoes infected with the bacterium Wolbachia into several Fresno County neighborhoods in 2016. (heartlanddailynews.com)

We have evidence our Wolbachia method is safe, sustainable and dramatically reduces incidence of dengue. (aljazeera.com)
This reduces the number of Aedes aegypti mosquitoes. (healthtoday.net)

A 2019 study found that accelerating urbanization and human movement would also contribute to the spread of Aedes mosquitoes. (wikipedia.org)

Aedes aegypti mosquitoes are also a challenging foe because they are most active during the day - meaning that's when they bite - so bed nets aren't much help against them. (whnt.com)
Male mosquitoes do not bite. (bigpinekey.com)
Male mosquitoes, which can live on nectar (if it's available), don't bite. (usf.edu)
And one mosquito can bite many times over, snacking repeatedly on the same human or moving from one to the next. (physiciansweekly.com)
Only female mosquitoes typically bite. (hindustantimes.com)
In the arid climate of the Central Valley, disease is an unlikely result of a mosquito bite. (hindustantimes.com)
Suppressing female mosquitoes is critical to preventing the spread of mosquito-borne diseases, because only females bite. (heartlanddailynews.com)

Since female mosquitoes pass Wolbachia to their offspring, they will eventually "replace" a local mosquito population with one that carries the virus-blocking bacteria. (whnt.com)
More than two years after completion of mosquito releases, Wolbachia has persisted at a very high level in the local mosquito population. (worldmosquitoprogram.org)

Bradley White, the lead scientist on the Debug initiative, said mosquito-suppression is even more important during the pandemic, so that outbreaks of mosquito-borne diseases such as dengue fever don't further overwhelm hospitals. (hindustantimes.com)

Here, we use powerful Evolve and Resequence approaches in the mosquito, Wolbachia and in the virus to (1) understand the likely mechanism of pathogen blocking, and (2) determine the most likely genetic paths through which resistance will emerge in the mosquito and the virus. (grantome.com)
The long-term efficacy of this strategy will be limited if resistance against Wolbachia evolves in either mosquitoes or the virus. (grantome.com)
Fitness costs in the presence and absence of insecticide use explains abundance of two common Aedes aegypti kdr resistance alleles found in the Americas. (mvcac.org)
Unlike conventional fogging methods, which are both expensive and lead to mosquito resistance, Wolbachia offers a safer and more powerful solution. (expresshealthcaremgmt.com)
Even if unexpected challenges occurred during deployment, such as emergence of resistance in the medium-term or low effective coverage, Wolbachia would remain a cost-saving intervention. (biomedcentral.com)

When these male mosquitoes mate with females in the wild, the offspring never hatch. (hindustantimes.com)

One strand of my recent work has examined the potential public health benefits of Wolbachia, a novel biological control to reduce the ability of Aedes aegypti mosquitoes to transmit dengue. (imperial.ac.uk)

With more than half the world's population at risk of contracting dengue, the World Health Organization is paying close attention to the mosquito releases in Honduras, and elsewhere, and it is poised to promote the strategy globally. (mystateline.com)
The trial involved releasing Wolbachia into the mosquito population across specific parts of Yogyakarta to measure how it affected the incidence of infections among three to 45-year-olds. (aljazeera.com)
The Wolbachia carrying mosquitoes - both male and female - then went on to mate with the wild mosquito population, resulting in the spread and establishment of the virus-inhibiting bacteria. (gla.ac.uk)
Use of the bacterial parasite has two potential advantages compared to other approaches: It doesn't rely on toxic chemicals and, once it is introduced, the bacteria spread rapidly through the mosquito population and sustain themselves. (phys.org)
2017): Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti. (ist.ac.at)
And the mosquitoes being released don't terrorize the local population. (gatesnotes.com)
Wolbachia can, therefore, be used to either replace the existing mosquito population with a lower competence phenotype by releasing females or suppress existing population by releasing males. (biomedcentral.com)
Replacement programmes with Wolbachia entail substantial initial investments to establish Wolbachia in the mosquito population through intensive releases at the beginning of the programme but potentially offer considerable long-term benefits. (biomedcentral.com)
But it does import cases - California has registered seven cases of imported dengue this year - and with the mosquito population growing, experts say it's likely only a matter of time. (physiciansweekly.com)
mosquitoes (especially Aedes aegypti ), the continued risk of severe disease and death, and the expansion out of historical areas of transmission, where all the population, including risk groups and healthcare workers, may not be aware of warning signs. (typepad.com)
The first explored the population genomics of Aedes aegypti in Metropolitan Manila, Philippines. (mecohlab.com)
In results of the trial published on Monday, Verily revealed that throughout the peak of the 2018 mosquito season, from July to October, Wolbachia-infected males successfully suppressed more than 93% of the female mosquito population at field test sites. (hindustantimes.com)
In most collections, per night Verily found one or zero female mosquitoes in each trap designed to monitor the population. (hindustantimes.com)
During a three-year period, tests will be carried out on the mosquito population to determine the percentage of Wolbachia mosquitoes. (msf-seasia.org)
Although males sterilized with X-rays continue to maintain the ability to mate with females of the wild population without leaving offspring, they present a success of mating less than that of non-irradiated male mosquitoes . (mosquitoalert.com)
New control technologies of Aedes aegypti in their adult fully tested yet in large population groups, particularly those form(11). (bvsalud.org)

The Food and Drug Administration has approved the world's first vaccine to prevent chikungunya, a mosquito-borne illness that can cause debilitating joint pain for months to years. (mvcac.org)
One of these pests is the mosquito Aedes aegypti , which causes catastrophic damage throughout the world's tropical zone. (edu.au)
This is a huge problem: The World Health Organization cites mosquitoes as one of the world's deadliest animals. (usf.edu)

However, for the reproduction of mosquitoes to be affected there must be an incompatibility between the variants of the bacteria carried by the female and the male. (mosquitoalert.com)

When mosquitoes carry Wolbachia , the transmission of mosquito-borne diseases is reduced. (worldmosquitoprogram.org)

When these mosquitoes reproduce, they pass the bacteria to their offspring, reducing future outbreaks. (mystateline.com)
California so far has avoided local outbreaks of the diseases carried by Aedes aegypti . (physiciansweekly.com)

Release of virus-blocking Wolbachia -infected mosquitoes is an emerging disease control strategy that aims to control dengue and other arboviral infections. (biomedcentral.com)
Testing the idea in the lab showed the mosquitoes were 68 percent less likely to become infected with dengue after sipping infected blood from human patients than were mosquitoes without wMel bacterial infections. (edu.au)

Dengue is the most rapidly spreading mosquito-borne disease in the world with more than 50 million cases globally every year, including about eight million in Indonesia. (aljazeera.com)
Infecting and spreading mosquitoes with Wolbachia has been successfully field tested in Australia, Brazil, Columbia, Indonesia and Vietnam. (phys.org)
The randomized controlled trial conducted in Yogyakarta, Indonesia, found that Wolbachia -carrying mosquitoes reduced the number of dengue cases in the city by 77 percent and dengue hospitalizations by 86 percent . (gatesnotes.com)
With the successful implementation of Wolbachia in Indonesia, this groundbreaking innovation in dengue prevention holds immense promise for the global fight against this debilitating disease. (expresshealthcaremgmt.com)

Here, we show that Wolbachia influences female fecundity, fertility, and re-mating incidence and significantly extends the longevity of virgin females. (geneconvenevi.org)
With time, the sterilizing effect of Wolbachia will become apparent, significantly reducing the mosquito-borne disease burden in the long run. (expresshealthcaremgmt.com)
In intervention areas, this has so far resulted in sharp declines in Aedes aegypti numbers in the wild as well as significantly less dengue virus. (interestingengineering.com)
Evidence shows that virus transmission is significantly reduced in areas where Wolbachia is maintained at a high level. (msf-seasia.org)

It is time-consuming, requires considerable human resources and the marking of a large number of mosquitoes to avoid bias. (nature.com)

Anatomy7

Organisms20

Diseases5

Chemicals and Drugs9

Psychiatry and Psychology1

Phenomena and Processes17

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture1

Information Science3

Health Care9

Geographicals1

Pipientis9

Populations21

Zika33

Species23

World Mosquito Program7

Albopictus4

Bacterium called4

Viruses17

Arboviruses8

20233

Eggs17

Strain12

Strains6

Disease-carrying m1

Infection12

Larvae5

Insects5

Release of Wolbachia-infected1

Vectors3

Female Aedes aegypti1

Reducing mosquito-borne1

Malaria5

Insect9

Bacteria called3

Sterile5

Humans13

Viral7

Genetically engineered mosquitoes1

Pathogens2

Yellow fever1

Widespread2

Million mosquitoes3

Reduce dengue1

Researchers10

Several Fresno County neighborhoods2

Reduces2

20191

Bite7

Local mosquito population2

Diseases such as dengue fever1

Resistance5

Male mosquitoes mate1

Transmit dengue1

Population16

World's3

Incompatibility1

Transmission of mosquito-borne1

Outbreaks2

Infections2

Indonesia4

Significantly4

Large number of mosquitoes1