1996Roslin InstituteSomatic cellParkinson'sShinya Yamanaka1944CryopreservationColleagueDolly the SWarwickshireScientistEmbryoResearchUniversityWorkCreationMadeProduceFieldColin TudgeRoslin Institute in EdinburghDollyUniversity of NottingDolly'sWilmut's1999Professor Keith CampbellScientistsScottishGenerateSciencesCellPotential
19965
- Wilmut was the leader of the research group that in 1996 first cloned a mammal, a lamb named Dolly. (wikipedia.org)
- Yamanaka also noted that experiments in cloning Dolly the sheep in 1996, conducted by Ian Wilmut, Angelica Schnieke, Jim McWhir, Alex Kind, and Keith Campbell at the Roslin Institute in Roslin, Scotland, influenced his work. (asu.edu)
- Wilmut, along with Keith Campbell from the animal sciences research institute in Scotland, generated news headlines and heated ethical debates in 1996 when they created Dolly, the first mammal to be cloned from an adult cell. (cyprus-mail.com)
- Wilmut, along with his colleague Keith Campbell and their research team, achieved a monumental milestone in the world of science by successfully cloning the first mammal from an adult cell - famously known as Dolly the Sheep in 1996. (biotecnika.org)
- 49] The Institute won international fame in 1996, when its researchers Ian Wilmut, Keith Campbell and their colleagues created Dolly the sheep, the first mammal to be cloned from an adult cell. (asaliftco.com)
Roslin Institute2
- Ian Wilmut and Keith H S Campbell worked together in the Roslin Institute near Edinburgh for many years, using sheep as the model, in order to understand the early physiology of the egg and how laboratory manipulations can improve our knowledge of the development from egg to birth. (shawprize.org)
- After graduating with a BSc in Genetics from the University of Edinburgh, Dr. Rahman completed a PhD in Molecular Biology at the Roslin Institute, University of Edinburgh under the supervision of Sir Ian Wilmut in 2007. (nottingham.ac.uk)
Somatic cell3
- In 2008 Wilmut announced that he would abandon the technique of somatic cell nuclear transfer by which Dolly was created in favour of an alternative technique developed by Shinya Yamanaka. (wikipedia.org)
- The inventors on the '233 application, Dr. Keith H.S. Campbell and Sir Ian Wilmut, were the first to produce a cloned mammal from an adult somatic cell -- Dolly the sheep. (patentdocs.org)
- Dr. Campbell and Sir Ian obtained U.S. Patent No. 7,514,258 for the method they used to produce Dolly: somatic cell nuclear transfer, which involves removing the nucleus of a somatic cell that has been arrested in the quiescent phase of the cell cycle and implanting that nucleus into an enucleated oocyte. (patentdocs.org)
Parkinson's3
- Wilmut believed that this method holds greater potential for the treatment of degenerative conditions such as Parkinson's disease and to treat stroke and heart attack patients. (wikipedia.org)
- Wilmut died from complications of Parkinson's disease on 10 September 2023, aged 79. (wikipedia.org)
- Ian Wilmut, a renowned British embryologist famous for his groundbreaking work in cloning and stem cell research, has sadly passed away at the age of 79 due to Parkinson's disease. (biotecnika.org)
Shinya Yamanaka1
- He, Keith Campbell and Shinya Yamanaka jointly received the 2008 Shaw Prize for Medicine and Life Sciences for their work on cell differentiation in mammals. (wikipedia.org)
19441
- Sir Ian Wilmut OBE FRS FMedSci FRSE (7 July 1944 - 10 September 2023) was a British embryologist and the chair of the Scottish Centre for Regenerative Medicine at the University of Edinburgh. (wikipedia.org)
Cryopreservation2
- In 1966, Wilmut spent eight weeks working in the laboratory of Christopher Polge, who is credited with developing the technique of cryopreservation in 1949. (wikipedia.org)
- The following year Wilmut joined Polge's laboratory to undertake a Doctor of Philosophy degree at the University of Cambridge, from where he graduated in 1971 with a thesis on semen cryopreservation. (wikipedia.org)
Colleague3
- Ian Wilmut, quoted in Time Wilmut led the team that created Dolly, but in 2006 admitted his colleague Keith Campbell deserved "66 per cent" of the invention that made Dolly's birth possible, and that the statement "I did not create Dolly" was accurate. (wikipedia.org)
- Keith was also an outstanding colleague whose absence leaves a huge gap. (nottingham.ac.uk)
- Professor Neil Crout, Head of the School of Biosciences, said: "Keith was a valued and respected colleague who will be sadly missed across the School of Biosciences. (nottingham.ac.uk)
Dolly the S5
- Professor Campbell was instrumental in the creation of Dolly the Sheep, the first cloned mammal, a breakthrough which paved the way for the successful cloning of many other mammal species. (nottingham.ac.uk)
- Professor Sir Ian Wilmut, who worked with Professor Campbell on the creation of Dolly the Sheep, said: "Always cheerful and friendly, Keith will be greatly missed by all of his friends and colleagues. (nottingham.ac.uk)
- British scientist Ian Wilmut, whose research was central to the creation of the cloned animal, Dolly the Sheep, has died at the age of 79, the University of Edinburgh said on Monday. (cyprus-mail.com)
- Farewell to a Genius: Ian Wilmut, the Man Who Gave Us Dolly the Sheep, is No More! (biotecnika.org)
- Ian Wilmut, Keith Campbell, and their dedicated team made history when they created Dolly the Sheep. (biotecnika.org)
Warwickshire1
- Wilmut was raised in Coventry, a town in the historic English county of Warwickshire, and he attended the Agricultural College at the University of Nottingham. (mathisfunforum.com)
Scientist3
- Tributes have been paid to internationally renowned scientist Professor Keith Campbell, who has died at the age of 58. (nottingham.ac.uk)
- Professor David Greenaway, Vice-Chancellor of The University of Nottingham, said: "Keith was a brilliant scientist. (nottingham.ac.uk)
- Professor Jus St.John, Director of the Centre for Reproduction & Development at Monash University, Australia, said: "Keith Campbell was an outstanding and inventive scientist whose foresight and work led to major changes in how we now ask scientific questions and make significant advances. (nottingham.ac.uk)
Embryo2
- Wilmut was appointed OBE in 1999 for services to embryo development and knighted in the 2008 New Year Honours. (wikipedia.org)
- Wilmut was appointed Officer of the Order of the British Empire (OBE) in the 1999 Birthday Honours "for services to Embryo Development" and a Fellow of the Royal Society (FRS) in 2002. (wikipedia.org)
Research1
- Professor Campbell was a cell biologist/embryologist with a research career spanning more than 30 years, the majority of which was in the field of cell growth and differentiation. (nottingham.ac.uk)
University4
- As a schoolboy, Wilmut worked as a farm hand on weekends, which inspired him to study Agriculture at the University of Nottingham. (wikipedia.org)
- Wilmut was an Emeritus Professor at the Scottish Centre for Regenerative Medicine at the University of Edinburgh and in 2008 was knighted in the New Year Honours for services to science. (wikipedia.org)
- Professor Kevin Sinclair worked with Professor Campbell at the University of Nottingham's School of Biosciences. (nottingham.ac.uk)
- Wilmut, who was born near Stratford-upon-Avon, attended the University of Nottingham, initially to study agriculture, before switching to animal science. (cyprus-mail.com)
Work2
- Professor Campbell was known around the world for his pioneering work and was jointly awarded the Shaw Prize for Life Science and Medicine in 2008. (nottingham.ac.uk)
- Since then, the work of Wilmut and Campbell has been duplicated in many other animal species and has provided approaches to produce useful therapeutic products with cloned animals and to improve agricultural practices. (shawprize.org)
Creation2
- His supervisory role is consistent with the post of principal investigator held by Wilmut at the time of Dolly's creation. (wikipedia.org)
- Wilmut and Campbell, in conjunction with Colin Tudge, published The Second Creation in 2000. (wikipedia.org)
Made1
- Wilmut, who drove the group that made Dolly, declaredin 2007 that the atomic exchange procedure may never be adequately proficientfor use in people.In 2016 researchers announced no deformities in thirteencloned sheep, including four from a similar cell line as Dolly. (maryelizabethbodycare.com)
Produce2
- The technique synchronized the cell cycles of both cells and the results led Wilmut and Campbell to believe that any type of cell could be used to produce a clone. (shawprize.org)
- Following the Dolly experiment's success, Ian Wilmut shifted his focus towards utilizing cloning technology to produce stem cells. (biotecnika.org)
Field1
- Professor Sinclair said: "Keith was a giant in the field of reproductive biology. (nottingham.ac.uk)
Colin Tudge1
- Wilmut and Campbell, in conjunction with Colin Tudge, published The Second Creation in 2000. (wikipedia.org)
Roslin Institute in Edinburgh2
- The Roslin Institute in Edinburgh has officially announced the sad news of the death of renowned British scientist Ian Wilmut, whose groundbreaking research revolutionised the world of biology and ignited intense ethical debates. (theweek.in)
- The effort to clone Dolly was led at the Roslin Institute in Edinburgh by Prof Sir Ian Wilmut, who later abandoned research on SCNT. (world-topnews.com)
Dolly11
- Wilmut was the leader of the research group that in 1996 first cloned a mammal, a lamb named Dolly. (wikipedia.org)
- In 2008 Wilmut announced that he would abandon the technique of somatic cell nuclear transfer by which Dolly was created in favour of an alternative technique developed by Shinya Yamanaka. (wikipedia.org)
- Ian Wilmut, quoted in Time Wilmut led the team that created Dolly, but in 2006 admitted his colleague Keith Campbell deserved "66 per cent" of the invention that made Dolly's birth possible, and that the statement "I did not create Dolly" was accurate. (wikipedia.org)
- Together with his colleague Keith Campbell at the animal sciences research institute in Scotland, Ian Wilmut made international headlines and stirred profound ethical discussions back in 1996 when they unveiled their remarkable creation: Dolly the Sheep, the first-ever mammal cloned from an adult cell. (theweek.in)
- Under the leadership of Dr. Ian Wilmut, Dolly became the first mammal to be successfully cloned from an adult cell, shattering previously held beliefs about genetic replication. (theweek.in)
- Ten years later Dolly the cloned sheep was created by nuclear transfer from an adult cell by Scottish scientists Keith Campbell and Ian Wilmut. (sciencefictionbiology.com)
- Before Dolly, people thought it was impossible," Professor Wilmut tells the BBC News website. (bbc.co.uk)
- I an Wilmut admits to some good fortune when he created the lamb named Dolly, the first mammal to be cloned from the DNA of an adult animal. (nih.gov)
- So it was actually attempts to manipulate the sheep genome, not clone it, that led Wilmut and his colleagues to produce Dolly. (nih.gov)
- Dolly with research leader Sir Ian Wilmut. (thelimbic.com)
- Professor Keith Campbell, who was part of the Dolly team, went on to improve the efficiency of SCNT so that 20% of cloned embryos developed to become live offspring, as opposed to the original 3% in the Dolly experiment. (thelimbic.com)
University of Notting2
- As a schoolboy, Wilmut worked as a farm hand on weekends, which inspired him to study Agriculture at the University of Nottingham. (wikipedia.org)
- Wilmut, a native of Stratford-upon-Avon, began his academic journey at the University of Nottingham, where he initially pursued studies in agriculture. (theweek.in)
Dolly's3
- His supervisory role is consistent with the post of principal investigator held by Wilmut at the time of Dolly's creation. (wikipedia.org)
- I am slightly disappointed by the fact that, technically, cloning is only slightly better than it was originally," explained Professor Ian Wilmut, one of Dolly's creators who is now based at Edinburgh University. (bbc.co.uk)
- Professor Keith Campbell, one of Dolly's creators, now based at Nottingham University, said: "The idea would be to use cloning to introduce beneficial genetic changes into animals or to reproduce superior genetic animals to breed back into the population. (bbc.co.uk)
Wilmut's2
- Wilmut's father, Leonard Wilmut, was a mathematics teacher who suffered from diabetes for fifty years, which eventually caused him to become blind. (wikipedia.org)
- Bruce Whitelaw, the director of the Roslin Institute, paid tribute to Wilmut, stating, 'With the sad news today of Ian Wilmut's passing, science has lost a household name. (theweek.in)
19992
- Wilmut was appointed OBE in 1999 for services to embryo development and knighted in the 2008 New Year Honours. (wikipedia.org)
- Wilmut was appointed Officer of the Order of the British Empire (OBE) in the 1999 Birthday Honours "for services to Embryo Development" and a Fellow of the Royal Society (FRS) in 2002. (wikipedia.org)
Professor Keith Campbell1
- Professor Keith Campbell. (thelimbic.com)
Scientists2
- On March 13, Scottish researcher Ian Wilmut filled Masur Auditorium and several overflow rooms with scientists and others eager to learn of his coup defeating the dogmas of mammalian cell differentiation. (nih.gov)
- seized the moment, dispatching NIDCD Fellow David Ehrenstein to conduct a one-on-one interview with Wilmut after he'd addressed the NIH masses, Scientific Editor Celia Hooper to snap photos of Wilmut engaged in this dialogue, and Managing Editor Fran Pollner to cover the ethics panel deliberations, the results of which may well shape the types of cloning-related research NIH scientists will be allowed to pursue. (nih.gov)
Scottish2
- Sir Ian Wilmut OBE FRS FMedSci FRSE (7 July 1944 - 10 September 2023) was a British embryologist and the chair of the Scottish Centre for Regenerative Medicine at the University of Edinburgh. (wikipedia.org)
- Wilmut was an Emeritus Professor at the Scottish Centre for Regenerative Medicine at the University of Edinburgh and in 2008 was knighted in the New Year Honours for services to science. (wikipedia.org)
Generate1
- Following the groundbreaking achievement, Wilmut redirected his focus towards employing cloning techniques to generate stem cells for use in regenerative medicine, aiming to unlock new frontiers in healthcare. (theweek.in)
Sciences1
- He, Keith Campbell and Shinya Yamanaka jointly received the 2008 Shaw Prize for Medicine and Life Sciences for their work on cell differentiation in mammals. (wikipedia.org)
Cell1
- Wilmut realized that the sheep cell lines he had already made, which were also derived from interior blastocyst cells, might be useful for manipulating genes after all, if he used them as nuclear donors. (nih.gov)
Potential1
- Wilmut believed that this method holds greater potential for the treatment of degenerative conditions such as Parkinson's disease and to treat stroke and heart attack patients. (wikipedia.org)