Whole body biotransformation in vivo. Medical search. Frequent questions

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Anatomy11

Microsomes, Liver Liver Muscle, Skeletal Bile Feces Hepatocytes Microsomes Intestines Adipose Tissue Kidney Gills

Organisms24

Cunninghamella Gordonia Bacterium Oncorhynchus kisutch Rats, Sprague-Dawley Berberidaceae Rats, Inbred F344 Hepatophyta Dogs Rats, Wistar Ictaluridae Mucorales Pseudomonas putida Rhodococcus Aspergillus ochraceus Nuphar Lactobacillus brevis Photinia Micromonospora Fungi Chlorella Mucor Pseudomonas mendocina Anemarrhena Mice, Inbred C57BL

Diseases4

Heat Stress Disorders Body Weight Insulin Resistance Drug-Induced Liver Injury

Chemicals and Drugs119

Cytochrome P-450 Enzyme System Cytochrome P-450 CYP3A Ketoconazole Xenobiotics Trichloroethanes Aryl Hydrocarbon Hydroxylases Glucuronosyltransferase Glutathione Transferase Trinitrotoluene Glucuronides Mixed Function Oxygenases Oxygenases Cytochrome P-450 CYP1A1 Isoenzymes Carbon Radioisotopes Oxidoreductases, N-Demethylating Troleandomycin Cytochrome P-450 CYP1A2 Environmental Pollutants Hydrocarbons, Halogenated Glucuronates Equol Methoxyflurane Toluene Nitroglycerin Arylamine N-Acetyltransferase Cytochrome P-450 CYP2E1 Monoterpenes Fenthion Cytochrome P-450 CYP2D6 Water Pollutants, Chemical Norisoprenoids Leucine Ethylmorphine Benzaldehydes Cytochrome P-450 CYP2B1 Pharmaceutical Preparations Hydrocarbons, Aromatic Prodrugs 7-Alkoxycoumarin O-Dealkylase Coumarins Ethylmercuric Chloride Isoflavones Soil Pollutants Eugenol Hydrocarbons, Chlorinated Ethyl Ethers Alprazolam Glucose Ethoxyquin Triazines Atrazine Insulin Ethylmercury Compounds Steroid 16-alpha-Hydroxylase Parathion Enzyme Inhibitors Recombinant Proteins Catechols Flame Retardants Glutathione tert-Butyl Alcohol Triazolam Phenols Coumaric Acids Acrylonitrile Phenobarbital Pyrazolones Skin Lightening Preparations Arsenic Lithocholic Acid Octanes Steroid Hydroxylases Umbelliferones L-Lysine 6-Transaminase Dichloroethylenes Butylene Glycols Carboxylesterase Fluorides NADPH-Ferrihemoprotein Reductase Zearalenone Benzo(a)pyrene Polycyclic Hydrocarbons, Aromatic Mutagens Aminophenols Mercury Compounds Carcinogens Dichloroacetic Acid Blood Glucose Aldehyde Dehydrogenase Fluorenes Guaiacol Epoxide Hydrolases Norbornanes Pyrrolizidine Alkaloids Estrogens, Non-Steroidal Trifluoroacetic Acid Fatty Acids, Nonesterified Xylenes Aflatoxin B1 Transaldolase Antimitotic Agents Halothane Potassium Radioisotopes Alkanes Safrole Sulfotransferases Chenodeoxycholic Acid Nitro Compounds Styrenes Trichloroethylene Fungicides, Industrial Polychlorinated Biphenyls Hydrocarbons, Fluorinated Aniline Hydroxylase Polycyclic Compounds Methyl Ethers Esters Ursodeoxycholic Acid

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Whole Body Imaging Chromatography, High Pressure Liquid Plethysmography, Whole Body Mass Spectrometry Whole-Body Counting Gas Chromatography-Mass Spectrometry Magnetic Resonance Spectroscopy Chromatography, Liquid Administration, Oral Metabolic Clearance Rate Whole-Body Irradiation Tandem Mass Spectrometry Models, Biological Spectrometry, Mass, Electrospray Ionization Absorptiometry, Photon Metabolic Engineering Batch Cell Culture Techniques Spectrophotometry, Ultraviolet Body Weight Hyperthermia, Induced Body Temperature Chromatography, Thin Layer Radiation Dosage Glucose Clamp Technique Anesthesia, Inhalation Mutagenicity Tests Toxicity Tests Reference Values Area Under Curve Bioreactors Calorimetry, Indirect Injections, Intravenous

Phenomena and Processes40

Biotransformation Dealkylation Hydroxylation Metabolic Detoxication, Phase I Oxidation-Reduction Metabolic Detoxication, Phase II Stereoisomerism Molecular Structure Kinetics Metabolic Detoxication, Drug Species Specificity Tissue Distribution Vibration Half-Life Body Composition Metabolic Clearance Rate Time Factors Energy Metabolism Drug Interactions Enzyme Induction Body Weight Intestinal Absorption Oxygen Consumption Dose-Response Relationship, Drug Biological Availability Body Temperature Regulation Biocatalysis Exercise Metabolic Networks and Pathways Body Temperature Physical Endurance Radiation Dosage Halogenation Insulin Resistance Diet Substrate Specificity Regional Blood Flow Area Under Curve Fermentation Bone Density

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena3

Exercise Physical Endurance Safety-Based Drug Withdrawals

Technology, Industry, Agriculture4

Metabolic Engineering Skin Lightening Preparations Biotechnology Bioreactors

Information Science1

Molecular Sequence Data

Health Care4

Biodegradation, Environmental Radiation Dosage Safety-Based Drug Withdrawals Area Under Curve

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Technology, Industry, Agriculture Information Science Health Care

Biotransformation Whole Body Imaging Cunninghamella Microsomes, Liver Cytochrome P-450 Enzyme System Chromatography, High Pressure Liquid Dealkylation Hydroxylation Cytochrome P-450 CYP3A Metabolic Detoxication, Phase I Plethysmography, Whole Body Liver Ketoconazole Biodegradation, Environmental Xenobiotics Oxidation-Reduction Mass Spectrometry Trichloroethanes Aryl Hydrocarbon Hydroxylases Glucuronosyltransferase Metabolic Detoxication, Phase II Whole-Body Counting Glutathione Transferase Trinitrotoluene Gas Chromatography-Mass Spectrometry Stereoisomerism Glucuronides Magnetic Resonance Spectroscopy Molecular Structure Mixed Function Oxygenases Kinetics Metabolic Detoxication, Drug Gordonia Bacterium Muscle, Skeletal Oxygenases Cytochrome P-450 CYP1A1 Species Specificity Tissue Distribution Isoenzymes Carbon Radioisotopes Oxidoreductases, N-Demethylating Troleandomycin Vibration Bile Half-Life Oncorhynchus kisutch Cytochrome P-450 CYP1A2 Feces Environmental Pollutants Rats, Sprague-Dawley Hydrocarbons, Halogenated Body Composition Chromatography, Liquid Hepatocytes Glucuronates Administration, Oral Equol Methoxyflurane Toluene Nitroglycerin Metabolic Clearance Rate Whole-Body Irradiation Berberidaceae Arylamine N-Acetyltransferase Cytochrome P-450 CYP2E1 Rats, Inbred F344 Time Factors Monoterpenes Microsomes Fenthion Energy Metabolism Cytochrome P-450 CYP2D6 Water Pollutants, Chemical Drug Interactions Norisoprenoids Hepatophyta Tandem Mass Spectrometry Leucine Dogs Ethylmorphine Benzaldehydes Cytochrome P-450 CYP2B1 Rats, Wistar Intestines Heat Stress Disorders Pharmaceutical Preparations Ictaluridae Hydrocarbons, Aromatic Mucorales Prodrugs Models, Biological Spectrometry, Mass, Electrospray Ionization 7-Alkoxycoumarin O-Dealkylase Coumarins Ethylmercuric Chloride Isoflavones Pseudomonas putida Soil Pollutants Eugenol Hydrocarbons, Chlorinated

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