- In this study, we compared the osteoinductivity of whitlockite, hydroxyapatite, and tricalcium phosphate porous particles with SD rat spine posterolateral fusion model and investigated whether whitlockite could induce ectopic ossification with SD rat abdominal pouch model. (biomedcentral.com)
- Whitlockite had a potential of being a better bone substrate hydroxyapatite and tricalcium phosphate in spinal fusion with low risk of inducing ectopic ossification. (biomedcentral.com)
- Significant differences were noted between the two groups including whitlockite relative mass, hydroxyapatite and whitlockite crystal maturity and, elementally, sodium to calcium ion ratio. (cancergrandchallenges.org)
- The four main crystal forms and their percentages are as follows: Hydroxyapatite: 58% Magnesium Whitlockite: 21% Octacalcium Phosphate: 12% Brushite: 9% Generally, 2 or more crystal forms are typically in a sample of calculus. (juniordentist.com)
- Minor phases: Euhedral chromites up to 0.5 cm, rounded whitlockite adjacent to olivine, and troilite heterogeneously distributed in thin veins. (usra.edu)
- 100 µm to several millimeters, that contain a complex mixture of olivine, low-Ca pyroxene, troilite, and whitlockite were observed adjacent to chromite. (usra.edu)
- The first serious studies of the mineral whitlockite were launched in 1952 on terrestrial specimens from the Palermo pegmatite quarry near North Groton, New Hampshire. (wikipedia.org)
- With regards to periodontal dentistry, magnesium whitlockite comprises one component of many of the inorganic content of calculus. (wikipedia.org)
- Magnesium whitlockite has been implicated in different disease states and is currently being studied for use in the fabrication of human prosthetics. (wikipedia.org)
- The second occurrence is extraterrestrial whitlockite, which is now known as merrillite. (wikipedia.org)
- Whitlockite is a mineral, an unusual form of calcium phosphate. (wikipedia.org)
- The P in SSA is not readily available as it appears mostly in the form of calcium phosphate, stanfieldite, whitlockite and berlinite. (degruyter.com)
- Whitlockite is a rare phosphate mineral often represented as a type of apatite. (wikipedia.org)
- Throughout all studies on whitlockite, it has been found that the two most common phosphate minerals occurring in lunar rocks were apatite and whitlockite, and that they usually occur together. (wikipedia.org)
- In the biologic literature, whitlockite and apatite are use interchangeably. (wikipedia.org)
- Whitlockite is also associated so frequently with apatite in its biologic occurrences that it is frequently presumed to be apatite. (wikipedia.org)
- The core, intermediate and surface envelopes consist in calcium phosphate apatite associated with whitlockite and amorphous carbonated calcium phosphate, all clarified by Fourier Transform InfraRed spectroscopy. (academie-sciences.fr)
- We propose to challenge this status quo by engineering the first bionanomaterial (Whitlockite)-based bone cement loaded with an immunotherapy drug for direct application to the bone. (grantome.com)
- In contrast, Whitlockite (WH) nanoparticles are a major component of bone, are stable in the acidic metastatic niche, and can be used for drug delivery. (grantome.com)
- The integration of immunotherapy with Whitlockite nanoparticles can lead to a paradigm shift in the treatment of bone metastasis, and directly impact a major unmet clinical need. (grantome.com)
- To solve this urgent and important problem, in this research project, we aim to develop an innovative anti-metastatic, immunomodulatory drug delivering Whitlockite nanoparticle-based bone cement that can be injected to the metastatic osteolytic lesion to reduce pain and inhibit metastatic cancer. (grantome.com)
- Whitlockite has been reported to promote better bone formation in rat calvaria models compare with them, but no study investigated its effect on spinal fusion yet. (biomedcentral.com)
- The micro-CT result from the posterolateral fusion model showed whitlockite had slightly but significantly higher percent bone volume than tricalcium phosphate, though none of the materials formed successful fusion with surrounding bone tissue. (biomedcentral.com)
- The result from the abdominal pouch model showed whitlockite did not induce ectopic bone formation. (biomedcentral.com)
- Neodymium and manganese ions co-doped whitlockite for temperature monitoring, photothermal therapy, and bone tissue repair in osteosarcoma. (bvsalud.org)
- In the present study, undoped whitlockite and ZnO doped-Whitlockite, which is the second most abundant inorganic material in bone structure, were synthesized from sea urchin skeleton. (iste.edu.tr)
- The first, known as terrestrial whitlockite, is found as a secondary mineral in granite pegmatites in such areas as Custer County, South Dakota, as dine crystals associated with quartz at the Tip Top mine, and at the Palermo mine in North Groton, New Hampshire. (wikipedia.org)
- There are two inorganic occurrences of whitlockite that differ chiefly by the presence or absence of hydrogen. (wikipedia.org)
- Organic instances of whitlockite are virtually identical in composition, but typically contain magnesium, which further distinguishes them from inorganic instances of this mineral. (wikipedia.org)
- Whitlockite has two inorganic occurrences with geologic significance. (wikipedia.org)
- Using neodymium (Nd) and manganese (Mn) ions co-doped with whitlockite nanoparticle (Nd10%Mn10%WH NPs) and sodium alginate (SA), we designed and synthesized an organic-inorganic composite hydrogel (Nd10%Mn10%WH-SA) that displayed the excellent fluorescence and photothermal properties. (bvsalud.org)
- Olivine (Fa I7.3), bronzite (Fs 16.5), diopside (Wo 45.3 En 49.0 Fs 5.7), oligoclase (Ou 5.4 Ab 84.1 An I0.4). (aimeteorites.com)
- Whitlockite is a member of the phosphate group of minerals with three distinct occurrences. (wikipedia.org)
- Although the identity of the "true" whitlockite is still debated, efforts are now being made to officially distinguish terrestrial whitlockite from its phase in meteorites as two distinct minerals. (wikipedia.org)
- Bobdownsite is a variety of whitlockite from Yukon, Canada, that was thought to contain fluorine bonded directly to phosphorus, giving it the chemical formula Ca9(Mg)(PO4)6(PO3F) However, subsequent investigation failed to find any monofluorophosphate in samples of bobdownsite, the mineral was discredited as a distinct species, and recommendations were made to tighten the criteria for identifying minerals as containing monofluorophosphate. (wikipedia.org)
- Extraterrestrial whitlockite has been identified in lunar samples as well as martian and other types of meteorites, where it is one of the most common phosphate minerals. (wikipedia.org)
- However, recent studies using x-ray and electron diffraction have been able to identify compositional differences that separate one type of whitlockite from another. (wikipedia.org)
- For example, increase in magnesium contents in solution resulted in precipitation of a phase pure Mg-Whitlockite phase. (qmul.ac.uk)
- Whitlockite can also be found in different types of biological deposits. (wikipedia.org)
- Also, the higher osteoinductivity of whitlockite raised concern of ectopic ossification, which was a complication of spinal fusion surgery that should be avoided. (biomedcentral.com)
- At higher concentrations of H3PO4 whitlockite crystallizes, and at concentrations above similar to 11.4% H3PO4 (at 800 degrees C, 385 MPa) an immiscible P-Fe melt forms. (uct.cl)
- With regards to periodontal dentistry, magnesium whitlockite comprises one component of many of the inorganic content of calculus. (wikipedia.org)
- Organic instances of whitlockite are virtually identical in composition, but typically contain magnesium, which further distinguishes them from inorganic instances of this mineral. (wikipedia.org)
- Magnesium whitlockite has been implicated in different disease states and is currently being studied for use in the fabrication of human prosthetics. (wikipedia.org)
- Basic calcium phosphate (BCP) crystals are predominantly composed of partly carbonate-substituted hydroxyapatite, but also include octacalcium phosphate, tricalcium phosphate and magnesium whitlockite. (medscape.com)
- Accessory minerals such as diopside En49.2 Fs7.0 Wo43.8, chromite, native copper, pentlandite and whitlockite. (aimeteorites.com)
- Whitlockite is a mineral, an unusual form of calcium phosphate. (wikipedia.org)
- Hi @Image Analyst , I'm working on a study concerning the microcalcifications of breast cancer, my goal is to show that a type of calcium called Whitlockite tends to form aggregates located on the edge of another form of calcium called hydroxyapatite. (mathworks.com)
- The characterization by HRXRD and DSC revealed the occurrence of whitlockite soon after the bulk glass preparation, a transient non-cataloged silicate between 800 ℃ and 1100 ℃, and the formation of diopside in samples treated at 1100 ℃ as crystalline phases. (sciopen.com)
- The first, known as terrestrial whitlockite, is found as a secondary mineral in granite pegmatites in such areas as Custer County, South Dakota, as dine crystals associated with quartz at the Tip Top mine, and at the Palermo mine in North Groton, New Hampshire. (wikipedia.org)
- Whitlockite is a rare phosphate mineral often represented as a type of apatite. (wikipedia.org)
- The first serious studies of the mineral whitlockite were launched in 1952 on terrestrial specimens from the Palermo pegmatite quarry near North Groton, New Hampshire. (wikipedia.org)
- Bobdownsite is a variety of whitlockite from Yukon, Canada, that was thought to contain fluorine bonded directly to phosphorus, giving it the chemical formula Ca9(Mg)(PO4)6(PO3F) However, subsequent investigation failed to find any monofluorophosphate in samples of bobdownsite, the mineral was discredited as a distinct species, and recommendations were made to tighten the criteria for identifying minerals as containing monofluorophosphate. (wikipedia.org)
- El fósforo es un mineral esencial que se encuentra en muchos alimentos. (medlineplus.gov)
- In the study, scientists created a synthetic version of the mineral known as whitlockite. (takecare4.eu)
- Whitlockite can also be found in different types of biological deposits. (wikipedia.org)
- Although the identity of the "true" whitlockite is still debated, efforts are now being made to officially distinguish terrestrial whitlockite from its phase in meteorites as two distinct minerals. (wikipedia.org)
- However, recent studies using x-ray and electron diffraction have been able to identify compositional differences that separate one type of whitlockite from another. (wikipedia.org)
- I then created an array of cells with the district of this type of pixel ("aggregates"), and to know if they are at the border of hydroxyapatite (defined by the number 1 in the cell array) I thought of merging the individual contents of neighboring pixels into a single pixel containing the information of the whole whitlockite aggregate. (mathworks.com)
- To simulate the effect of being thrown from Mars, scientists blasted the synthetic whitlockite samples with metal plates that were fired from guns at about 1,678 miles per hour and with huge amounts of pressure. (takecare4.eu)