Whereas lysine molecular chains. Medical search. Frequent questions

Protein carbonylation occurs in arginine, histidine, lysine, proline and threonine residues and it truly is regarded as an irreversible course of action [165]. (hivinhibitor.com)
ATTO390-Actin is chemically modified cardiac G-actin with an ATTO390 fluorescent group covalently bound to lysine residues. (hypermol.com)
Methyltetrazine-PEG4-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. (vectorlabs.com)
To examine the role of water penetration, we have measured the 17O and 2H magnetic relaxation dis- persions (MRD) for the V66E and V66K mutants of staphylococcal nuclease, where glutamic acid and lysine residues are buried in predominantly apolar environments. (lu.se)

We are a leading Manufacturer of fmoc-l-aspartic acid-beta allyl ester, l-glutamic acid dibenzyl ester hcl, fmoc l lysine allyloxycarbonyloxy, fmoc-l-lys(boc)-oh and n-fmoc-s-acetamidomethyl-l-cystein from Bengaluru, India. (siddhivinayakaspechem.com)
Lancet 335: 1589 (1990)] found an A-to-G transition which resulted in the substitution of lysine (AAA) by glutamic acid (GAA) at residue 329 of the enzyme (K329E). (coriell.org)

This report describes a microbial toxin mechanism acting via iso-peptide bond cross-linking between host proteins and is, to the best of our knowledge, the only known example of a peptide linkage between nonterminal glutamate and lysine side chains. (rcsb.org)
the sulphenic acid-containing side chains of proteins form covalent bonds with low-molecular-weight thiols, mainly with glutathione. (hivinhibitor.com)
The new structure shows that, like a wrench in the works, halofuginone jams the gears of a molecular machine that carries out "aminoacylation," a crucial biological process that allows organisms to synthesize the proteins they need to live. (med-chemist.com)
Our results demonstrated the potential role of P. lima in the removal of phenthoate in water and exemplified the crucial proteins and their possible molecular mechanisms underpinning the phenthoate remediation by P. lima and also the regulatory role of phenthoate in restricting the OA metabolism. (bvsalud.org)
The ionizable amino acid side chains of proteins are usually located at the surface. (lu.se)
All or other nearby charged groups, the pKa shift of a buried pH-dependent properties of proteins are ultimately governed residue is dominated by the large electrostatic self-energy by the electrostatic interactions of ionizable side chains. (lu.se)

Molecular Biology and Evolution , 2022, Roč. (cuni.cz)
Molecular Biology of the Cell. (quantabiodesign.com)
Our new results solved a mystery that has puzzled people about the mechanism of action of a medicine that has been used to treat fever from a malaria infection going back probably 2,000 years or more," said Paul Schimmel, PhD, the Ernest and Jean Hahn Professor and Chair of Molecular Biology and Chemistry and member of The Skaggs Institute for Chemical Biology at TSRI. (med-chemist.com)
This is fundamental and interesting molecular biology you need anyway, and another secret of life. (physicsforums.com)
Despite recent progresses in uncovering the biology underlying age-related diseases, and improvements in research focused on the molecular mechanisms of age-related diseases, our knowledge of the cellular mechanisms that regulate key mitochondrial energy substrate enzymes in the aging heart is greatly underdeveloped. (wvu.edu)

The person suggests that someone should focus on the chemical nature of the groups on the side chains, the peptide bond structure, the number of carbons in the side chain of leucine or lysine, and how they typically interact with each other. (physicsforums.com)
Knowing how many carbon atoms the side chain of leucine or lysine etc. have is rubbish , I don't remember for certain. (physicsforums.com)

An amino acid derivative synthesized from methionine and lysine, required in energy metabolism. (medscape.com)

The corresponding MD simulations, which are complemented by a novel Hamiltonian replica exchange approach, then reveal a structural heterogeneity within the binding pocket of the retinal chromophore, which mainly pertains to the structure of the lysine chain covalently connecting the retinal chromophore with the protein backbone. (sfb749.de)
Glycation, is a spontaneous non-enzymatic reaction in which glucose binds covalently with haemoglobin at amino terminus of the b-globin chain. (org.pk)
the lysine side chain (with a -NH2 terminus, a primary amine) is commonly used to covalently attach labels to antibody molecules. (novusbio.com)

In the second, tripeptides, specifically KYF (Lysine- Tyrosine - Phenylalanine) and DFF (Aspartic Acid- Diphenylalanine), are added to these aggregates in order to study the tripeptide stabilized nanoemulsions. (google.com)

In parallel, ER-residing molecular chaperones, such as HSPA5/GRP78/BiP, are relocated to the cytosol and conjugated with the amino acid L-arginine (Arg) at the N-termini by ATE1 (arginyltransferase 1). (nih.gov)
Protein folding is often mediated by molecular chaperones. (rcsb.org)

The tags are generally monomeric, though in the case of histone methylation, multiple methyl groups can be appended to a single amino acid side chain. (physicsforums.com)

Poly-D-Lysine is a synthetic amino acid chain that is positively charged and widely used as a coating to enhance cell attachment and adhesion to both plasticware and glass surfaces. (advancedbiomatrix.com)
The colored portion of the molecule in this illustration shows positively charged lysine and negatively charged aspartate interacting in the required axial geometry that stabilizes the triple helix. (analytica-world.com)

As indicated earlier, the molecular mass of a chemical is based on the number of protons and neutrons that is contained in each atom ( eg NaCl is made up of one molecule of Na, M.W. = 22.99g and one molecule of Cl, M.W. = 35.45g, so the M.W. of NaCl is 58.44g). (assignmentexpert.com)
Carnitine is an important small water-soluble molecule that binds to long-chain fatty acids and facilitates their transport across the inner mitochondrial membrane and into the mitochondrial matrix to undergo fatty acid oxidation (metabolism). (medscape.com)

Tentacle-like protrusions enclose the polypeptide chains of the pre-protein during the folding process. (rcsb.org)

However, it is not possible to measure moles on a laboratory balance, so in the first instance chemicals are measured by mass (milligrams, grams, kilograms etc) and the number of moles is calculated using the known molecular mass (often called molecular weight and abbreviated to M.W.) of the chemical. (assignmentexpert.com)
For example, for NaCl you need to pick the atomic weight of both sodium and chlorine and then add them to two decimal places to obtain the molecular mass of NaCl. (assignmentexpert.com)
B ) Table showing observed molecular weight and calculated molecular weight for monomeric protein of H-NS 1-57. (elifesciences.org)
Activated protein C resistance and low molecular weight lipoprotein (a): dual pathogens for atherothrombosis? (mcmaster.ca)
Actin from bovine cardiac muscle is a single chain polypeptide with a molecular weight of 42kD consisting of 375 amino acids. (hypermol.com)
The impact of molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Poly L-Lysine Dendrimers. (quantabiodesign.com)
Reaction with collagen gave both broad anisotropic signals, from high-molecular-weight protein-derived radicals, and isotropic signals from mobile species. (ku.dk)
Enzymatic digestion of the large, protein-derived, species releases similar low-molecular-weight adducts. (ku.dk)
This product's molecular weight ranges from 70,000 to 150,000 Da. (advancedbiomatrix.com)
This product's molecular weight ranges from 70,000 to 150,000 Da yielding a solution viscosity for easy handling while providing sufficient binding sites for cell attachment. (advancedbiomatrix.com)
Peginterferon alfa-2a, is a covalent conjugate of recombinant alfa-2a interferon (approximate molecular weight [MW] 20,000 daltons) with a single branched bis-monomethoxy polyethylene glycol (PEG) chain (approximate MW 40,000 daltons). (mdtodate.com)
Peginterferon alfa-2a has an approximate molecular weight of 60,000 daltons. (mdtodate.com)
Whether it is for protein electrophoresis or western blot, our pre-stained protein markers help you quickly determine the molecular weight of the target protein or evaluate the transfer efficiency. (acrobiosystems.com)

BARD1 tandem BRCA1 C-terminus (BRCT) motifs fold into a binding pocket with a key lysine residue (K619), and bind to poly(ADP-ribose) (PAR), which targets the BRCA1/BARD1 heterodimer to damaged DNA sites. (wikipedia.org)
One inhibition possibility is the BARD1 BRCT key lysine residue (K619). (wikipedia.org)

LC = 'long chain' version with an additional aminohexanoic acid spacer between the biotin and lysine side chain. (anaspec.com)
Attack of the hydroxyl radical, from a Fe(II)-H2O2 redox couple, on collagen peptides gave signals from both side chain (.CHR'R{'}), and alpha-carbon[.C(R)(NH-)CO-,R = side-chain]radicals. (ku.dk)
these signals are similar to those from the alpha-carbon site of peptides and the side-chain of lysine. (ku.dk)
Side Chain Protected Amino Acids. (siddhivinayakaspechem.com)
So know the peptide bond structure, the chemical types of side chain, with a name to which aa falls in each type. (physicsforums.com)
In addition to the amine and carboxyl functional groups, amino acids also contain a side chain that is unique to each group. (jackednutrition.pk)

After the assembly, a sensory mechanism for correctly folded beta-helices triggers a serine-lysine catalytic dyad to autoproteolytically release the mature protein. (rcsb.org)

Rice scientists who have learned how to make collagen - the fibrous protein that binds cells together into organs and tissues - are now digging into its molecular structure to see how it forms and interacts with biological systems. (analytica-world.com)

During this 2-step process, the ER transmembrane E3 ligase TRIM13 undergoes auto-ubiquitination via lysine 63 (K63) linkage chains and acts as a ligand for the autophagic receptor SQSTM1/p62 (sequestosome 1). (nih.gov)

Carnitine is a quaternary ammonia water-soluble compound biosynthesized from lysine and arginine. (medscape.com)

The actin cross-linking domain (ACD) of MARTX(Vc) directly catalyzes a covalent cross-linking of monomeric G-actin into oligomeric chains and causes cell rounding, but the nature of the cross-linked bond and the mechanism of the actin cytoskeleton disruption remained elusive. (rcsb.org)

Gillingham MB, Scott B, Elliott D, Harding CO. Metabolic control during exercise with and without medium-chain triglycerides (MCT) in children with long-chain 3-hydroxy acyl-CoA dehydrogenase (LCHAD) or trifunctional protein (TFP) deficiency. (medscape.com)

Although you may sometimes see it written as g/litre, the concentration of solutions is more often described in term of molarity since it better defines the chemical properties of a solution because it is proportional to the number of molecules or ions in solution, irrespective of molecular mass of its constituents. (assignmentexpert.com)

Hydroxyacyl-CoA Dehydrogenase (HADHA) and Long Chain Acyl-CoA Dehydrogenase (LCAD) catalyze the oxidation of long chain fatty acids, whereas pyruvate dehydrogenase (PDH) catalyzes glucose oxidation in the heart. (wvu.edu)
Schiff M, Mohsen AW, Karunanidhi A, McCracken E, Yeasted R, Vockley J. Molecular and cellular pathology of very-long-chain acyl-CoA dehydrogenase deficiency. (medscape.com)
Scalais E, Bottu J, Wanders RJ, Ferdinandusse S, Waterham HR, De Meirleir L. Familial very long chain acyl-CoA dehydrogenase deficiency as a cause of neonatal sudden infant death: Improved survival by prompt diagnosis. (medscape.com)
Peripheral sensory-motor polyneuropathy, pigmentary retinopathy, and fatal cardiomyopathy in long-chain 3-hydroxy-acyl-CoA dehydrogenase deficiency. (medscape.com)
Gillingham MB, Purnell JQ, Jordan J, Stadler D, Haqq AM, Harding CO. Effects of higher dietary protein intake on energy balance and metabolic control in children with long-chain 3-hydroxy acyl-CoA dehydrogenase (LCHAD) or trifunctional protein (TFP) deficiency. (medscape.com)

This is one of the three branched-chain amino acids (BCAAs). (jackednutrition.pk)
The influence of alternative pathways of respiration that utilize branched-chain amino acids following water shortage in Arabidopsis. (mpg.de)

Be sure to multiply the atomic masses by the number of individual atoms of the same element present in each compound before finally adding to the masses of other component atoms of other elements to make up the total molecular masses. (assignmentexpert.com)

The two protein chains forming the dimer are color-coded. (elifesciences.org)

It serves as a mechanism for transport of long-chain fatty acids from the cytoplasm across the inner mitochondrial membrane and into the mitochondrial matrix, the site of b-oxidation of fatty acids for energy generation. (medscape.com)
The molecular mechanism(s) of UPR induction by Chlamydia is unknown. (cdc.gov)

A ) Comparison of nonpolar contacts of H-NS orthologs at 20°C and 0.15M NaCl, using the last 100 ns in the molecular dynamics (MD) simulations. (elifesciences.org)

His doctoral work involved biochemical characterization of DNA cutting enzymes (Meganuclease) and designing 'on/off' switch for temporal regulation of 'molecular scissors' for efficient genome editing. (stanford.edu)

C ) The tetrameric H-NS ST model we used for molecular dynamics (MD) is shown. (elifesciences.org)
Conserved inter-dimer salt bridges observed in molecular dynamics (MD) simulations. (elifesciences.org)
As a prerequisite, one needs a MM model of the chromophore−protein complex, which allows a correct sampling of its room-temperature equilibrium fluctuations by molecular dynamics (MD) simulation. (sfb749.de)

and (3) other molecular pathways that are involved in neural response to acupuncture. (hindawi.com)

We offer a selection of recent papers on a variety of topics from the Journal of Biological Chemistry , the Journal of Lipid Research and Molecular & Cellular Proteomics . (asbmb.org)
The most important thing they do, enzymic catalysis, depends on the chemistry of their side chains. (physicsforums.com)

Use in long-chain fatty acid oxidation disorders (eg, LCHAD deficiency, MTP deficiency) is a matter of continued debate, mainly during acute fulminant crises when it enhances the formation of long-chain acylcarnitines, which may cause ventricular arrhythmogenesis. (medscape.com)
Management and outcome in 75 individuals with long-chain fatty acid oxidation defects: results from a workshop. (medscape.com)

Molecular, chemical, and genome biologist elucidating the functional role of repetitive DNA sequences. (stanford.edu)
So the first thing to focus is the chemical nature of the groups on the side chains. (physicsforums.com)

These values can be found in the periodic table however the molecular mass of chemicals is generally provided by any vendors of the products and so can also be found on various suppliers' websites. (assignmentexpert.com)
Using periodic table found in your textbook, calculate (to 2 decimal places) the molecular mass for each of the compounds used to make PBS. (assignmentexpert.com)

Polyelectrolyte properties are intrinsic, not only to a multitude of single macromolecules, but also to their organized structures and molecular assemblies. (mdpi.com)

Neurofilament light chain (NfL) is a neuronal cytoplasmic protein highly expressed in large calibre myelinated axons. (bmj.com)

Bromodomains can interact specifically with acetylated lysine [3]. (rcsb.org)

To facilitate identification of R. mannitolilytica and R. pickettii , we developed 16S ribosomal DNA-based polymerase chain reaction assays that allow sensitive and specific identification of these species. (cdc.gov)
We also describe the development and evaluation of two polymerase chain reaction (PCR) assays for rapid, accurate identification of R. pickettii and R. mannitolilytica . (cdc.gov)
Polymerase chain reaction assayed. (who.int)

Then rapIdly move on to tertiary structure (the 3-D folding of the chain) in connection with some functions asap. (physicsforums.com)
That indicates that one side of its molecular structure has a chain branching out of it. (jackednutrition.pk)

Successful coupling of peptide epitopes to beads followed three steps: 1) development of a peptide tag appended to the C-terminus of each peptide epitope consisting of beta-alanine-lysine (x 4)--cysteine, 2) bead modification with a high concentration of adipic acid dihydrazide, and 3) use of the peptide epitope as a blocker in place of the traditional choice, bovine serum albumin (BSA). (cdc.gov)

L-carnitine at high doses corrects the metabolic abnormalities and hypocarnitinemia present in cases of long-chain 3-hydroxy acyl-coenzyme A dehydrogenase (LCHAD) deficiency. (medscape.com)
Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency and choroidal neovascularization]. (medscape.com)
Clinical, biochemical, and morphologic investigations of a case of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. (medscape.com)
Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency: clinical presentation and follow-up of 50 patients. (medscape.com)
Acute dilated cardiomyopathy in a patient with deficiency of long-chain 3-hydroxyacyl-CoA dehydrogenase. (medscape.com)
Optimal dietary therapy of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. (medscape.com)

however, the concentration of long-chain acyl-carnitines increases, which can be detrimental and cause serious cardiac arrhythmias in fulminant crises. (medscape.com)

Poly-D-Lysine surface coatings are designed to improve cell attachment, growth and differentiation of many cell types. (advancedbiomatrix.com)

In nature, these small structures link into chains that serve as connective tissue in the body. (analytica-world.com)

EHEC), enteropathogenic E. coli (EPEC), ditional and molecular diagnostic methods enteroinvasive E. coli (EIEC), and entero- in patients with acute diarrhoea in Hamedan aggregative E. coli (EAEC). (who.int)

This assembly was very different when compared to the aggregation of single chains of oleic acid. (google.com)
The PEG moiety is linked at a single site to the interferon alfa moiety via a stable amide bond to lysine. (mdtodate.com)

For example, lysine 27 of the histone H3 protein (referred to as H3K27) can have either one, two or three methyl groups attached and the different methylation states are associated with different biological functions. (physicsforums.com)
The activated dye can be reacted under appropriate conditions with antibodies (all of which have multiple lysine groups). (novusbio.com)

We investigated the hypothesis that T3SS effector-mediated assembly of myosin-II complex produces activated non-muscle myosin heavy chain II (NMMHC-II), which then binds the UPR master regulator (BiP) and/or transducers to induce UPR. (cdc.gov)

Hybrid methods, which combine a quantum mechanical description of a chromophore by density functional theory (DFT) with a molecular mechanics (MM) model of the surrounding protein binding pocket, can enable highly accurate computations of the chromophore's in situ vibrational spectra. (sfb749.de)

Anatomy5

Organisms6

Diseases1

Chemicals and Drugs66

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Phenomena and Processes45

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science3

Health Care2

Residues4

Glutamic acid2

Proteins6

Biology5

Leucine2

Methionine1

Covalently3

Phenylalanine1

Chaperones2

Amino acid side1

Positively charged2

Molecule2

Polypeptide chains1

Weight13

Residue2

Side chain6

Catalytic1

Collagen1

Linkage1

Arginine1

Covalent1

Medium-chain triglyc1

Ions1

ACYL-CoA DEHYDROGE5

Branched-chain2

Compound1

Protein chains1

Mechanism2

NaCl1

Characterization1

Dynamics3

Pathways1

Chemistry2

Fatty2

Chemical2

Mass2

Macromolecules1

Neuronal1

Interact1

Polymerase3

Structure2

Modification1

Dehydrogenase6

Cardiac1

Growth1

Structures1

Diagnostic1

Single2

Groups2

Binds1

Density1