• Here we report an acute phase reaction to at least one of the Gd compounds used for MRI investigation, i.e. diethylenetriamine penta-acetic acid (Gd-DTPA). (medscape.com)
  • A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid ( DTPA see PENTETIC ACID ), that is given to enhance the image in cranial and spinal MRIs. (bvsalud.org)
  • DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) is an amphiphilic molecule with paramagnetic property. (sigmaaldrich.com)
  • A system comprising a primary amine organic extractant and an aqueous eluent containing diethylenetriaminepentaacetic acid (dtpa) was less effective for separating the rare earths. (cdc.gov)
  • Gadoteridol is synthesized by reacting the chelating agent DTPA (diethylenetriaminepentaacetic acid) with gadolinium chloride. (evitachem.com)
  • In order to minimize the potential risks associated with gadolinium deposition in the brain, it must be used in strict accordance with the indications and approved doses. (beilupharma.com)
  • Compared to other gadolinium-based MRI contrast agents, Gadopentetate dimeglumine (Gd-DTPA2-) chelates allow delayed Gadolinium-enhanced Magnetic Resonance of Cartilage (dGEMRIC). (handwiki.org)
  • Gadoteridol is a paramagnetic compound that contains a central gadolinium ion surrounded by a chelating agent (DTPA) and two hydrophilic side chains. (evitachem.com)
  • Modified [frequency-shifted (FS)] BURST MRI was performed during injection of a bolus of Gd-DTPA (0.13 mmol/kg) in the antecubital vein. (johnshopkins.edu)
  • Sixteen 3-second images of the same section were obtained at 13-second intervals immediately after Gd-DTPA administration, and again at 30 or 50 minutes after injection. (houstonmethodist.org)
  • In 2020, Beilu launched its macrocyclic Contrast Media- Gadobutrol Injection, it is gadolinium-based non-ionic Contrast Media, a paramagnetic Contrast Media used in various parts of the body lesion (including the brain and spinal cord) MRI imaging and angiography examination. (beilupharma.com)
  • micro MRI was performed following injection with gadolinium-DTPA-A beta(1-40). (nih.gov)
  • Axial T(2), T(1)-weighted imaging, and a dynamic study after a gadolinium injection were performed. (alljournals.cn)
  • Long-Term in Vivo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection. (nano-h.fr)
  • Thermodynamic Stability and Kinetic Inertness of a Gd-DTPA Bisamide Complex Grafted onto Gold Nanoparticles. (nano-h.fr)
  • 2. [A pharmacokinetic analysis of Gd-DTPA enhancement in MRT in breast carcinoma]. (nih.gov)
  • 8. Pharmacokinetic analysis of Gd-DTPA enhancement in dynamic three-dimensional MRI of breast lesions. (nih.gov)
  • Cardiac function was analyzed with magnetic resonance imaging (MRI), and accurate infarct size was obtained with late gadolinium enhancement. (nature.com)
  • In the gadolinium-enhanced dynamic study, a recurrent HCC showed early enhancement, followed by a rapid washout. (alljournals.cn)
  • Several late sequelae of the administration of gadolinium (Gd)-containing MRI contrast agents have been described in patients with advanced renal failure. (medscape.com)
  • In an observational series, we found a remarkable frequency of peracute reactions after administration of Gd-DTPA used for cardiovascular evaluation before renal transplantation. (medscape.com)
  • To determine if magnetic resonance imaging with Gd-DTPA could be used to assess renal and hepatic perfusion and possibly function, a fast-field-echo technique was used to perform sequential imaging of the kidney and liver of five subjects. (houstonmethodist.org)
  • An overview of the impact of field strength, parallel imaging, and dynamic imaging techniques as well as the use of improved gadolinium chelates on renal MRA will be provided in this review. (biomedcentral.com)
  • Gd-DTPA-BSA is useful as magnetic resonance imaging (MRI) agent and the gadolinium ion enables the generation of bright images by lowering the longitudinal relaxation time. (sigmaaldrich.com)
  • 1. Dynamic contrast-enhanced magnetic resonance imaging of the breast combined with pharmacokinetic analysis of gadolinium-DTPA uptake in the diagnosis of local recurrence of early stage breast carcinoma. (nih.gov)
  • 17. Intraindividual in vivo comparison of gadolinium contrast agents for pharmacokinetic analysis using dynamic contrast enhanced magnetic resonance imaging. (nih.gov)
  • A convincing body of study supports this idea, including the pursuing research: First, the record of leptomeningeal abnormalities on Gd-DTPA (gadolinium) improved magnetic resonance (MRI) imaging that may reflect meningeal hurdle abnormalities17. (hwupdate.org)
  • Measurements of task-induced changes in cerebral blood volume (CBV) have been demonstrated using VAscular Space Occupancy (VASO) techniques (noninvasive and newly developed) and a contrast agent-based (Gd- DTPA) method (invasive but well-established) with functional magnetic resonance imaging (fMRI). (openneuroimagingjournal.com)
  • The gadolinium ion has seven unpaired electrons, which makes it highly reactive to magnetic fields. (evitachem.com)
  • Current evidence shows that after repeated use of GBCAs, trace amounts of gadolinium can remain in the brain and other body tissues. (beilupharma.com)
  • Animal experiments have shown that the amount of gadolinium deposited after repeated use of linear GBCAs is higher than that of repeated use of macrocyclic. (beilupharma.com)
  • It is a member of the group of gadolinium-based contrast agents (GBCAs) that are widely used in clinical practice. (evitachem.com)
  • Gadolinium-based contrast agents (GBCAs) increase the risk for NSF among patients with impaired elimination of the drugs. (nih.gov)
  • The use of newer contrast agents, such as high relaxivity or protein binding Gadolinium (Gd)-chelates, also improves image quality, particularly when combined with SNR gains available at 3 T. These factors have also allowed a reduction in the contrast agent dose necessary to achieve diagnostic image quality. (biomedcentral.com)
  • Gd-DTPA in clinical MR of the brain: I. Intraaxial lesions. (ajnr.org)
  • 4. Suspect breast lesions: findings at dynamic gadolinium-enhanced MR imaging correlated with mammographic and pathologic features. (nih.gov)
  • At present, the number of new gadolinium enhancing lesions on monthly MRI of the brain is one of the most used measures of outcome to monitor multiple sclerosis (MS) activity. (bmj.com)
  • Gadopentetic acid , sold under the brand name Magnevist , is a gadolinium -based MRI contrast agent . (handwiki.org)
  • Co-infusion of PEGylated Gd-DTPA liposomes and TMZ-liposomes by CED in GBM bearing rats, resulted in enhanced tumor detection with longer residence time than free Gd-DTPA. (huji.ac.il)
  • Evaluation of a Gadolinium-Based Nanoparticle (AGuIX) for Contrast-Enhanced MRI of the Liver in a Rat Model of Hepatic Colorectal Cancer Metastases at 9.4 Tesla. (nano-h.fr)
  • The gadolinium ion has 7 unpaired electrons with parallel spins and is strongly paramagnetic with an 8 S electronic ground state. (handwiki.org)
  • This water molecule is labile and exchanges rapidly with water molecules in the immediate vicinity of the gadolinium complex. (handwiki.org)
  • This effect is due to the interaction between the gadolinium ion and the surrounding water molecules, which results in a reduction in the T1 relaxation time. (evitachem.com)
  • 5. Comparative signal intensity measurements in dynamic gadolinium-enhanced MR mammography. (nih.gov)
  • Brain tumors: MR imaging with gadolinium-DTPA. (ajnr.org)
  • Secondary outcomes included blood-brain barrier (BBB) breakdown on gadolinium-enhanced MRIs and 90-day modified Rankin scores (mRS). (bmj.com)
  • Gadolinium is highly toxic and the accumulation of gadolinium in the brain has become a concern. (handwiki.org)
  • Gadolinium is retained for months or years in brain, bone, and other organs. (nih.gov)
  • It remains unresolved whether the reaction observed with Gd-DTPA do in principle also occur with other Gd reagents. (medscape.com)
  • Cite this: Acute Phase Reaction to Gadolinium-DTPA in Dialysis Patients - Medscape - Apr 01, 2009. (medscape.com)
  • Added value of enhanced CT on LR-3 and LR-4 observation of Gd-EOB-DTPA MRI for the diagnosis of HCC: are CT and MR washout features interchangeable? (nih.gov)
  • The agent is a prolonged circulating gadolinium containing macromolecule that consists of a monomethoxy ether of polyethylene glycol attached to poly L lysine?Gd DTPA. (alksignaling.com)
  • In a 26-month observational period, 13 of 136 haemodialyzed or CAPD patients exhibited onset of fever, chills and nausea within hours after administration of Gd-DTPA peracute. (medscape.com)
  • Gadolinium-enhanced MRI was performed in 50 patients with ventricular dysfunction before they underwent surgical or percutaneous revascularization. (nih.gov)
  • Nine male patients with suspected recurrence after radiotherapy for HCC underwent T(2)-, T(1)-weighted imaging and Gd-DTPA enhanced dynamic studies. (alljournals.cn)
  • Nebulized Gadolinium-Based Nanoparticles: A Theranostic Approach for Lung Tumor Imaging and Radiosensitization. (nano-h.fr)
  • In addition, our study shows, for the first time, the utility of micro MRI in conjunction with gadolinium-labeled A beta labeling agents to monitor the therapeutic response to amyloid-reducing agents. (nih.gov)