Western gag protein gag gene products human immunodeficiency virus. Medical search. Frequent questions

Simian virus infections of humans are an increasing highly prevalent in several animal species in which they public health concern. (cdc.gov)
Simian foamy virus (SFV) infections cause persistent infections ( 16 - 26 ). (cdc.gov)
2) trace the origin of virus and simian T-cell lymphotropic virus ( 12 - 15 ). (cdc.gov)
HIV-2 is more closely related to simian immunodeficiency virus (SIV) and is concentrated in western Africa. (mhmedical.com)
One such protein is viral protein U (Vpu) that is encoded by HIV-1 but not HIV-2 or the simian immunodeficiency virus (SIV) [ 2 ]. (biomedcentral.com)

The development of sensitive and specific tests for antibody to human immunodeficiency virus type 1 (HIV-1) progressed rapidly after this retrovirus was identified as the cause of acquired immunodeficiency syndrome (AIDS). (cdc.gov)
HIV-1 was thought to be the only cause of these syndromes until 1986, when a second type of Human Immunodeficiency Virus (HIV-2) was isolated and also reported to cause AIDS (acquired immunodeficiency syndrome). (rapidtest.com)
The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). (biomedcentral.com)
The loss of CD4 helper/inducer T cell function probably underlies the profound defects in cellular and humoral immunity leading to the opportunistic infections and malignancies characteristic of the acquired immunodeficiency syndrome (AIDS) (Lane et al. (justia.com)

Diagnostic Automation offers a HIV 1, 2 ELISA kit is an enzyme-linked immunosorbent assay for the qualitative detection of antibodies to HIV type 1 (group M-O) or type 2 in human serum or plasma samples. (rapidtest.com)
Following the optimization of the reaction conditions, the Nb8-HRP fusion protein was successfully used to establish a competitive enzyme-linked immunosorbent assay (cELISA) to detect ASFV-specific antibodies in pig serum, for the first time. (bvsalud.org)

Env-specific antibody responses were detected in 15 (50%) of 30 vaccine recipients by enzyme-linked immunosorbant assay and in 28 (93.3%) of 30 vaccine recipients by immunoprecipitation followed by Western blotting. (emmes.com)
Serum samples that are repeatedly reactive in the EIA for HIV-1 antibody are then retested with a supplemental and more specific test, the most common of which is the Western blot (1-3). (cdc.gov)
In the wells where the antigen-antibody-antigen (HRP) sandwich immunocomplex is taking place, the colorless chromogens are hydrolyzed by the bound HRP conjugate to a blue-colored product. (rapidtest.com)
Human IgG antibody Laboratories manufactures the kit elisa antigène p24 price reagents distributed by Genprice. (oegterm.at)

Antibodies to the HIV-1 major group-specific antigen (GAG) protein p24, and its precursor p55, are the earliest detected after infection by Western blot and tend to decrease or become undetectable with onset or progression of clinical symptoms (4-9). (cdc.gov)
However, in a recent study, the protein with a mobility of 160 kilodaltons (kd) present in commercially available Western blots and in viral lysate antigen preparations was identified as a multimer of the gp41 protein (10,11). (cdc.gov)
HIV infection can be diagnosed based on detection of antibodies that are directed against the proteins encoded by the 3 major genes, the detection of the p24 antigen, the viral nucleic acid, and, finally, by means of culturing the virus. (medscape.com)
To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact p24 Antigen Elisa. (oegterm.at)

Human immunodeficiency virus (HIV) is a retrovirus which may lead to a immune systembegins failure and to opportunistic infections. (prospecbio.com)
FDA is updating the committee on XMRV, the newly identified human retrovirus (a gammaretrovirus), and FDAs collaborative efforts with other public health agencies and blood establishments to determine whether XMRV poses a safety concern for the blood supply. (phoenixrising.me)
Xenotropic Murine Leukemia Virus-Related Virus (XMRV) is a newly identified retrovirus and the first gammaretrovirus of the Retroviridae family detected in humans. (phoenixrising.me)
XMRV is a simple retrovirus with gag, pol and env genes and unlike HIV or HTLV, has no accessory or regulatory genes. (phoenixrising.me)

Table 1 lists the major structural proteins coded for by the HIV genome. (cdc.gov)
Nora Chapman et al from the Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Centre, have shown that human enteroviruses Coxsackie B can naturally delete sequence from the 5' end of the RNA genome and that this deletional mechanism results in long-term viral persistence, which has substantially altered the previously held view (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440640/?tool=pubmed). (investinme.org)
Marburg virus (MARV) is a lipid-enveloped virus harboring a negative sense RNA genome, which has caused sporadic outbreaks of viral hemorrhagic fever in Sub-Saharan Africa. (uci.edu)
By 2015, conducting research that was met with an enormous amount of concern, scientists at UNC had successfully created a "chimeric, SARS-like virus" by altering the viral genome of a Chinese bat coronavirus's spike-protein genes - sequences that code for the spikes that poke out from surface of viruses and allow them to unlock entry into hosts, in this case making the bio-engineered coronavirus incredibly contagious. (algora.com)
A full-genome evolutionary analysis of 2019-nCoV published in The Lancet concluded, "recombination is probably not the reason for emergence of this virus" since it seems that the Wuhan Strain isn't a mosaic of previously known coronaviruses, but instead draws from distant, discrete parts of the coronavirus family tree - not how these viruses naturally evolve. (algora.com)

Polypyrimidine tract binding protein and associated splicing factor (PSF) has diverse functions inside the cell such as transcriptional regulation, DNA repair, acts as nucleic acids binding protein and regulate replication and infectivity of different viruses. (biomedcentral.com)
We believe that these products are actually food for our genes-variants of nucleic acids and ATP-like energy compounds. (ascendedhealth.com)

The purpose of this report is to provide guidance for interpreting Western blot test results and their use in diagnosing HIV-1 infection. (cdc.gov)
However, under- bon and Cameroon ( 16 , 17 ), we investigated the presence standing of the initial steps of the emergence of some vi- of SFV infection in humans living in these regions. (cdc.gov)
Testing for the presence of HIV antigens or antibodies from serum brings serological evidence of infection from individuals that may be harboring the HIV virus. (rapidtest.com)
Human immunodeficiency viruses (HIVs) are lentiviruses, a family of retroviruses evolved to establish chronic persistent infection with gradual onset of clinical symptoms. (mhmedical.com)
Replication is constant following infection, and although some infected cells may harbor nonreplicating virus for years, in the absence of treatment there generally is no true period of viral latency following infection. (mhmedical.com)
Human Immunodeficiency Virus Type I (HIV-1) infection is associated with a high incidence of B-cell lymphomas. (biomedcentral.com)
Human Immunodeficiency Virus Type I (HIV-1) infection is associated with an elevated incidence of B-cell non-Hodgkin's lymphoma (NHL) and in recent years also with Hodgkin's lymphoma [ 1 ]. (biomedcentral.com)
Approximately 25 million deaths worldwide have been attributed to infection with human immunodeficiency virus (HIV) since the beginning of the HIV epidemic in the early 1980s. (medscape.com)
Timeline of CD4 T-cell and viral-load changes over time in untreated human immunodeficiency virus (HIV) infection. (medscape.com)
The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
The primary immunologic abnormality resulting from infection by human immunodeficiency virus (HIV) is the progressive depletion and functional impairment of T lymphocytes expressing the CD4 cell surface glycoprotein. (justia.com)
Like many other human malignancies, development of cervical cancer is a multi-step process, which is initiated by the infection of "high-risk" types of human papilloma viruses (HPV) such as HPV 16 or HPV 18. (biomedcentral.com)

Several small genes encode regulatory proteins that enhance virion production or combat host defenses. (mhmedical.com)
HIV-1 also has regulatory genes ( tat and rev ) and genes that encode for accessory proteins ( vpu , vpr , vif , and nef ) that are important in viral replication and interaction with the host. (medscape.com)

Murine models for human AIDS-related B cell lymphomas have been lacking. (biomedcentral.com)

In contrast, antibodies to the envelope (ENV) precursor protein gp160 and the final ENV proteins (gp120 and gp41) can be detected in specimens from virtually all HIV-infected persons regardless of clinical stage (4-9). (cdc.gov)
Furthermore, this study presented evidence that the reaction observed against the gp120 on certain Western blots may have resulted in part from a reaction with a multimeric form of the gp41. (cdc.gov)
In fact, the true gp120 was shown to be absent from some commercial Western blot antigens. (cdc.gov)
The currently licensed Du Pont Western blot test specifies that the test result should be interpreted as positive only when the detected bands include p24 and p31, and gp41 or gp120/160 (12) (see Table 2). (cdc.gov)
The first step is the interaction between envelope proteins of the virus (gp120, gp41) and specific host-cell surface receptors (e.g. (wikipedia.org)
Expression of B cell-stimulatory cytokines IL-1β, IL-6, IL-10, IL-12 p40 , IL-13 and TNFα and HIV proteins p17, gp120 and nef were elevated in the Tg mice with lymphoma. (biomedcentral.com)
It is disclosed herein that the HIV-1 envelope protein gp120 binds to α4β7 integrin on CD4+ T-cells, natural killer (NK) cells and CD8+ T-cells. (justia.com)

The Gag protein is the major structural protein required for virus assembly. (prospecbio.com)
A very critical step is the proteolytic cleavage of the polypeptide precursors into mature enzymes and structural proteins catalyzed by HIV protease. (wikipedia.org)
These drugs prevent proteolytic cleavage of HIV Gag and Pol polyproteins that include essential structural and enzymatic components of the virus. (wikipedia.org)
MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)

There are several steps in the HIV life cycle that may be interfered with, thus stopping the replication of the virus. (wikipedia.org)
This previously unknown and unsuspected aspect of enterovirus replication provides an explanation for reports of enteroviral RNA detected in diseased tissue in the apparent absence of virus particles" (Journal of IiME 2009:3:1). (investinme.org)
Virus was isolated from T- and B- lymphocytes and NK cells in blood (but not macrophages), prostate epithelial cells, vaginal tissue, and there was evidence for viral replication in spleen, lung, lymph nodes and liver (5). (phoenixrising.me)
The different interactions between viral proteins and cellular host proteins are required for efficient replication of HIV-1. (biomedcentral.com)
In an attempt to study the host interacting protein of IN, we have identified a new interacting host protein PSF which is a splicing factor and elucidated its role in integration and viral replication. (biomedcentral.com)
Identification of these interacting host cellular protein provide better understanding of mechanism of viral replication and subsequently development of new therapeutic approaches. (biomedcentral.com)
HIV persistence may arise from ongoing residual virus replication and/or from latently-infected cells defined as the cellular reservoir in which long-lived resting memory CD4+ T cells harbouring an integrated but transcriptionally silent provirus represent the largest pool in the blood (Chomont et al. (europa.eu)
Characterization of the replication defects of class II IN mutant viruses. (elifesciences.org)

Gag alone is sufficient to produce buddingvirus-like particles (VLP's) due to multimerization of roughly 2000 Gag molecules per virion.The Gag proteins take part throughout the viral life-cycle, including the assembly and release of viral particles, theirsubsequent maturation into infectious virions, and during the events occurring between therelease of capsids into newly infected cells and the integration of proviral DNA. (prospecbio.com)
Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly. (uci.edu)
Recently it was shown that herpes simplex virus type 1 (HSV-1) induces tetherin mRNA degradation via its virion host shutoff activity to counteract tetherin restriction[ 17 ]. (biomedcentral.com)
In some embodiments, methods and compositions are provided for creating and using virion-derived protein nanosphere particles (NSPs) that exhibit surprising selectivity for delivering molecules to tumors without targeting healthy tissue and without producing a serotype-specific immunogenic response in the subject. (justia.com)

HIV belongs to the class of viruses called retroviruses, which carry genetic information in the form of RNA. (wikipedia.org)
Whether Vpu is a viral pathogenesis factor remains to be established, but compared to HIV-1, closely related retroviruses such as HIV-2 and SIV that lack expression of a fully functional Vpu protein also cause less severe disease outcomes. (biomedcentral.com)

Selection analyses of paired HIV-1 gag and gp41 sequences obtained before and after antiretroviral therapy. (cdc.gov)

Serologic studies have also shown that the core proteins of HIV-1 and HIV-2 display frequent cross-reactivity whereas the envelope proteins are more type-specific. (rapidtest.com)
5′-aza-dC and/or Trichostatin A resulted in transcriptional upregulation of the genes, suggesting that low expression of ECM components, proteoglycan core proteins and HS biosynthetic system is due to epigenetic suppression in type I cells. (oncotarget.com)

Antibodies to the polymerase (POL) gene products (p31, p51, and p66) are also commonly detected if these antigens are present on the Western blot strips. (cdc.gov)
Although the overall sensitivity and specificity of the Western blot for detection of antibodies to the various viral proteins are high, there has been substantial debate regarding the interpretive criteria. (cdc.gov)
Finally, antibodies to XMRV were detected in 9/18 CFS patients using a test based on the envelope of a closely related virus, spleen focus forming virus (SFFV). (phoenixrising.me)
As a promising alternative diagnostic tool to traditional antibodies, nanobodies (Nb) have the advantages of simpler and faster generation, good stability and solubility, and high affinity and specificity, although the system is dependent on the immunization of Bactrian camels to obtain the specific VHH library of the target protein. (bvsalud.org)

The mRNA is then translated into viral proteins and the third virally encoded enzyme, namely HIV protease, is required to cleave a viral polyprotein precursor into individual mature proteins. (wikipedia.org)

Then the virus binds to the chemokine coreceptors CXCR4 or CCR5, resulting in conformational changes in the envelope proteins. (wikipedia.org)

Human immunodeficiency virus (HIV)-1 is a member of the Retroviridae family. (medscape.com)

HIV-1 GAG Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain, encoded by the HIV gag gene, HXB2 (790-2292) and having a molecular mass of 55.0kDa. (prospecbio.com)

These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell. (lookformedical.com)
In addition, mannosebinding-lectin (MBL) is an epithelial-cell associated host protein that binds to Candida mannan, activates complement, and thus inhibits Candida growth. (paperzz.com)

HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. (prospecbio.com)
DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated cytosine-guanosine (CpG) oligonucleotides, a motif often seen in bacterial or viral DNA. (uci.edu)

The env gene encodes for glycoprotein (gp) 120 and gp 41. (medscape.com)

The up-regulation of proto-oncogene may be the consequence of epigenetic control of gene expression by demethylase, and mbd2 is involved in the regulation of hMSH2 expression in human gastric cancer. (wjgnet.com)
Here, we demonstrate that the transcription factor E2F6, a member of the polycomb repressive complex 1.6 (PRC1.6), is critical to target and initiate epigenetic silencing at germline genes in early embryogenesis. (cnrs.fr)
Our findings elucidate the mechanisms of epigenetic targeting of germline genes and provide a paradigm for how transient repression signals by DNA-binding factors in early embryonic cells are translated into long-term epigenetic silencing during mouse development. (cnrs.fr)

Using Vpu proteins from a primary subtype C and the pNL4-3 subtype B isolates of HIV-1, we show oligomerization of the full-length protein as well as its transmembrane (TM) domain by genetic, biochemical and biophysical methods. (biomedcentral.com)
Genetic evidence supports sporadic and independent introductions of subtype H5 low pathogenic avian influenza A viruses from wild birds to domestic poultry in North America. (cdc.gov)

XMRV was identified using a viral detection DNA microarray composed of oligonucleotides corresponding to the most conserved sequences of all known viruses (1). (phoenixrising.me)
The viral gene sequences identified in CFS patients clustered with sequences from PC and both sequences were virtually identical. (phoenixrising.me)

Following entry into the cell the RNA of the virus is reverse-transcribed to DNA by the first virally encoded enzyme, the reverse transcriptase. (wikipedia.org)

We have clearly documented certain enterovirus infections triggering autoimmune responses in some patients…Can you imagine how we would feel if there are viruses surviving in our muscles, brains, hearts and gastrointestinal tracts triggering ongoing immune responses? (investinme.org)
This relates to the field of human immunodeficiency virus (HIV), specifically to the use of α4 integrin antagonists for the treatment of HIV infections. (justia.com)

The viral proteins are then transferred onto nitrocellulose paper and reacted with the patient's serum. (cdc.gov)
Positive and negative control serum specimens are run simultaneously to allow identification of viral proteins. (cdc.gov)
Afterwards, microwells are washed to remove unbound serum proteins. (rapidtest.com)
Similar to human HAL, Tg lymphomas are preceded by diffuse lymphadenopathy and increased pro-inflammatory serum cytokines. (biomedcentral.com)
There was no cross-reaction with healthy pig serum, porcine pseudorabies virus (PRV), porcine reproductive and respiratory syndrome virus (PRRSV), classical swine fever virus (CSFV), porcine epidemic diarrhea virus (PEDV), and classical swine fever virus (CSFV) positive sera. (bvsalud.org)
The Kit Elisa Antigène P24 Price reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (oegterm.at)

By themselves, viruses are lifeless particles incapable of reproduction, but once they enter the cell of another living thing they become active organisms that can multiply hundreds of times. (investinme.org)
The expelling of virus particles from the body. (lookformedical.com)

These data demonstrate effi cient transmission of SFVs to hu- of persons occupationally exposed to nonhuman primates mans in natural settings in central Africa, specifi cally follow- in zoos, primate centers, and laboratories, mainly in North ing ape bites, and viral persistence in the human host. (cdc.gov)
Human immunodeficiency virus (HIV) is a lentivirus that has two major species, HIV-1 which causes the majority of the epidemic, and HIV-2, a close relative whose distribution is concentrated in western Africa. (wikipedia.org)

Nuclear antigens encoded by VIRAL GENES found in HUMAN HERPESVIRUS 4. (lookformedical.com)

The viral RNA and viral proteins assemble at the surface of the cell into new virions. (wikipedia.org)
Electron microscopy of human immunodeficiency virus (HIV)-1 virions. (medscape.com)
A ) Immunoblot analysis of Gag and Gag-Pol products in cell lysates and virions. (elifesciences.org)

Preferential activation of microsomal diacylglycerol/protein kinase C signaling during glucose treatment (De Novo phospholipid synthesis) of rat adipocytes. (jci.org)
Glucose has been reported to increase the de novo synthesis of diacylglycerol (DAG) and translocate and activate protein kinase C (PKC) in rat adipocytes. (jci.org)
Magnesium is integral to the function of adenosine triphosphate and plays a role in a host of enzymatic reactions and transport processes, and in the synthesis of proteins, DNA and RNA. (irjs.info)

Using a phage display technology, one Nb against the ASFV p54 protein that exhibited high specificity and affinity, Nb8, was successfully screened. (bvsalud.org)

The transcriptional levels of p16 INK4A and MeCP2 genes did not display any difference between gastric cancerous and matched non-cancerous tissues. (wjgnet.com)
HIV-1-infected podocytes showed markedly elevated cyclin D 1 mRNA and cyclin D 1 protein, the latter of which did not down-regulate during cell-cell contact or differentiation, suggesting post-transcriptional stabilization of cyclin D 1 protein levels by HIV-1. (biomedcentral.com)
Interferon-β1 then drives interferon-stimulated transcriptional programs in both cancer cells and stromal fibroblasts and ultimately undermines the efficacy of oncolytic viruses, both in vitro and in vivo. (regenerativemedicine.net)

Viruses cause disease at the most basic level, by damaging the cells of living things. (investinme.org)
Knowing the essential features of the pathophysiology of this disease and how chemotherapeutic agents affect the virus and the host is critical in developing a rational approach to therapy. (mhmedical.com)
African swine fever (ASF), which is caused by the ASF virus (ASFV), is a highly contagious hemorrhagic disease that causes high mortality to domestic porcine and wild boars and brings huge economic losses to world swine industry. (bvsalud.org)
Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL). (lookformedical.com)

The type species is HERPESVIRUS 1, HUMAN . (lookformedical.com)

FLIM-FRET analysis of protein-protein interactions showed that PLIN5 S155 phosphorylation regulates PLIN5 interaction with adipose triglyceride lipase at the lipid droplet, but not with α-β hydrolase domain-containing 5. (uci.edu)
Most knowledge regarding the interaction between tetherin and viruses has been obtained using the primate lentiviral system. (biomedcentral.com)

There is increasing awareness that the dysregulated immune system that is a hall-mark of ME/CFS allows multiple latent viruses and microbial agents to become reactivated (Co-Cure NOT:12th November 2009). (investinme.org)
The mechanism by which latent viruses, such as genetically transmitted tumor viruses ( PROVIRUSES ) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. (lookformedical.com)

The anti-CD3 Dictionary of British Spy Fiction is a comprehensive protein of the detailed country and cells of the other engine immunodeficiency in differentiation, website and microenvironment. (kloevekorn.com)

Moreover, recent research has shown that even viruses which were hitherto believed not to persist after an acute infectious episode are capable of long-term viral persistence. (investinme.org)
Further investigation using activated CFS patient PBMC co-cultured with susceptible PC cells (LNCaP) showed that virus could be transmitted by cells and supernatant, as indicated by protein expression and transmission electron microscopy, suggesting that the virus being detected by protein expression was infectious. (phoenixrising.me)
Equine infectious anemia virus (EIAV) is an important macrophage-tropic lentivirus that has been widely used as a practical model for investigating the evolution of the host-virus relationship. (biomedcentral.com)
B ) Infectious titers of WT or IN mutant HIV-1 NL4-3 viruses in cell culture supernatants were determined on TZM-bl indicator cells. (elifesciences.org)
A patient who has hepatitis A (infectious hepatitis) should consume a diet that's moderately high in fat and high in carbohydrate and protein, and should eat the largest meal in the morning. (rnpedia.com)

â ¢ We establish a method for continuous and stable expression of Nb-HRP fusion protein using a lentiviral packaging system. (bvsalud.org)

The pol gene encodes the enzymes reverse transcriptase, integrase, and protease. (medscape.com)
The exocrine function of the pancreas is the secretion of enzymes used to digest carbohydrates, fats, and proteins. (rnpedia.com)

Trans-complementation of the HIV-1 NL4-3 IN D116N virus with mutant IN molecules restored particle release to levels comparable to WT IN (red), partially restored particle release (gray) or could not restore particle release (blue). (elifesciences.org)

Gammaretroviruses in animals are implicated in a wide range of diseases including cancers, immunodeficiency, and neurological disorders. (phoenixrising.me)
However, the transcription level of the above genes was not associated with biological behaviours of gastric cancers. (wjgnet.com)

The average mRNA level of Dnmt1 gene from cancerous tissue was higher and that of mbd2 gene from cancerous tissue was lower than that from non-cancerous tissue, respectively. (wjgnet.com)
In vivo , enhanced expression of the inflammation- and oxidative stress-related genes HO-1 and iNOS was found on the mRNA level in rat lungs after instillation with DQ12 respirable quartz. (biomedcentral.com)

Various reports implicated host cellular proteins as a key factor that either interact directly with HIV-1 integrase (IN) or get involved in the integration process of virus resulting in the modulation of integration step. (biomedcentral.com)
The protein binding study identified the association of host protein PSF with HIV-1 integrase. (biomedcentral.com)
Experimental as well as in silico analysis inferred that the host protein causes not only change in the integration events but also targets the incoming viral DNA or the integrase-viral DNA complex. (biomedcentral.com)
The integration process is catalyzed by viral protein integrase which utilizes different host proteins for integration of viral DNA [ 1 ]. (biomedcentral.com)
In the present study, we have identified a new HIV-1 integrase interacting protein, polypyrimidine tract binding protein and associated splicing factor (PSF) through pull down assay and co immunoprecipitation of IN with mammalian cell protein. (biomedcentral.com)

Perilipin 5 (PLIN5) is a lipid-droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). (uci.edu)

After other studies demonstrated high prevalence and have evolved and disseminated into the human population genetic diversity of SFVs in monkeys and apes in Ga- through various distinct mechanisms. (cdc.gov)
Deoxyribonucleic acid that makes up the genetic material of viruses. (lookformedical.com)
Viruses whose genetic material is RNA. (lookformedical.com)
Reduced levels of MBL and genetic polymorphisms in the MBL gene were found in women with RVVC. (paperzz.com)

HIV protease inhibitors are peptide-like chemicals that competitively inhibit the action of the virus aspartyl protease. (wikipedia.org)

Description: The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. (oegterm.at)

Tetherin is an interferon-inducible host cell factor that blocks the viral particle release of the enveloped viruses. (biomedcentral.com)
The HIV-1 Vpu protein is an oligomeric integral membrane protein essential for particle release, viral load and CD4 degradation. (biomedcentral.com)
In some embodiments, the nanosphere particle comprises wild-type HPV L2 capsid proteins. (justia.com)
In vitro , the direct, particle-mediated effect on proinflammatory signalling in a rat lung epithelial (RLE) cell line was compared to the indirect, macrophage product-mediated effect. (biomedcentral.com)

Compared to controls, cultured podocytes expressing HIV-1 genes, and podocytes and tubular epithelium from hyperplastic nephrons in Tg26 kidneys, had increased levels of phospho-pRb (Ser780), a target of active cyclin D 1 /cyclin-dependent kinase-4/6 known to promote G 1 → S phase progression. (biomedcentral.com)
The selective suppression of HIV-1 transcription by the cyclin-dependent kinase inhibitor, flavopiridol, abrogated cyclin D 1 expression, underlying the requirement for HIV-1 encoded products to induce cyclin D 1 . (biomedcentral.com)

Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)
A general term for diseases produced by viruses. (lookformedical.com)

Moreover, the availability of p53 is apparently important for chemokine regulation, since TNF-α can induce MCP-1 only in human keratinocytes expressing the viral oncoprotein E7, but not in HPV16 E6 positive cells, where p53 becomes degraded. (biomedcentral.com)

Description: Fourth-generation HIV immunoassays detect viral p24 protein in the blood. (oegterm.at)

To date, only one commercial Western blot test (Du PontPr) has been licensed by the Food and Drug Administration (FDA). (cdc.gov)
The Western blot assay is a method in which individual proteins of an HIV-1 lysate are separated according to size by polyacrylamide gel electrophoresis. (cdc.gov)
MybiosourceProduct Short Name: [Western Blot Stripping (Neutral)]Product Name Synonyme: N/AOther Names: N/AProduct Gene Name: N/AProduct Gene. (biocheminfo.org)
NEW LAV BLOT I and II (LAV I and LAV II), they were only option for human immunodeficiency virus (HIV) confirmatory test, following HIV screening test using HIV Ag/Ab combination test in Japan. (biomedcentral.com)
In Japan, specimens that are detected as human immunodeficiency virus (HIV)-positive via the screening test, using HIV Ag/Ab combination test, are subjected to a confirmatory test using western blot test. (biomedcentral.com)

A HEK293T cell line stably expressing Nb8-horseradish peroxidase (HRP) fusion protein was established using the lentiviral expression system. (bvsalud.org)

Here, we ask whether the expression of HIV-1 genes in infected podocytes induces cyclin D 1 and phospho-pRb (Ser780) expression, hallmarks of cyclin D1-mediated G 1 → S phase progression. (biomedcentral.com)

Indeed, HIV-1 virus deleted of nef failed to induce cyclin D 1 mRNA to the level of other single gene mutant viruses. (biomedcentral.com)

Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses. (lookformedical.com)

Anatomy20

Organisms36

Diseases20

Chemicals and Drugs88

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Psychiatry and Psychology5

Phenomena and Processes66

Information Science5

Named Groups1

Health Care6

Simian5

Acquired immunode4

Enzyme-Linke2

Antibody4

Antigen4

Retrovirus4

Genome5

NUCLEIC ACIDS2

Infection12

Encode2

AIDS1

Gp1207

Structural4

Replication8

Virion4

Retroviruses2

Gp411

Core proteins2

Antibodies4

Polyprotein1

Envelope proteins1

Retroviridae1

Recombinant1

Binds2

Dendritic cells2

Glycoprotein1

Epigenetic3

Subtype2

Sequences2

Virally encoded1

Infections2

Serum6

Particles2

Africa2

Antigens1

Virions3

Synthesis3

Specificity1

Transcriptional3

Disease4

Herpesvirus1

Interaction2

Latent viruses2

Differentiation1

Infectious5

Lentiviral packag1

Enzymes2

Molecules1

Cancers2

MRNA level2

Integrase5

Oxidative1

Genetic4

Protease1

Precursor1

Particle4

Kinase2

Diseases2

Expressing the viral1

Immunoassays1

Blot5

Fusion protein1

Induces1

Mutant viruses1

Control of gene1