Topoisomerase InhibitorsCamptothecinTopoisomerase I InhibitorsDNA Topoisomerases, Type INyssaceaeTopoisomerase II InhibitorsAntineoplastic Agents, PhytogenicTopotecanDNA Topoisomerases, Type IIEtoposideDNA TopoisomerasesAmsacrineWaterTrypanosoma rangeliEllipticinesEnzyme InhibitorsDNA DamageAntineoplastic AgentsDNA Topoisomerase IVTeniposideApoptosisTumor Cells, CulturedWater SupplyDNA, SuperhelicalCell Line, TumorCell CycleDoxorubicinCell SurvivalTumor Suppressor Protein p53DNADNA CleavageIntercalating AgentsFresh WaterBody WaterNovobiocinMolecular Sequence DataDrug Screening Assays, AntitumorRazoxaneDNA, CatenatedDNA-Binding ProteinsBase SequenceCamptothecaAntigens, NeoplasmWater PurificationWater Pollution