Clinically, angiokeratoma of Fordyce over the vulva should be differentiated from angiomas (cherry angiomas, pyogenic granuloma, and lymphangioma), verrucous lesions (seborrhoeic keratosis, condyloma acuminata, nodular prurigo, condyloma lata, and certain nevi), and malignancies (melanoma and vulvar intraepithelial neoplasia). (natoursprung.de)
Vaginal Atrophy5
When prescribing solely for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause, first consider the use of topical vaginal products. (nih.gov)
IMVEXXY (estradiol vaginal inserts) is an estrogen indicated for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. (imvexxyhcp.com)
Treatment of moderate to severe vasomotor symptoms due to menopause ) Treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to Limitation of Use: When prescribing solely for the treatment of moderate to severe Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism. (gotomydoctor.com)
the relief of menopausal and postmenopausal symptoms occurring in naturally or surgically induced estrogen deficiency states including vulvar and vaginal atrophy. (pfizermedicalinformation.ca)
When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered. (pfizermedicalinformation.ca)
Ovarian1
DICER1 tumor predisposition (DICER1) is characterized by an increased risk for pleuropulmonary blastoma (PPB), pulmonary cysts, thyroid gland neoplasia (multinodular goiter, adenomas, and/or thyroid cancer), ovarian tumors (Sertoli-Leydig cell tumor, gynandroblastoma, and sarcoma), and cystic nephroma. (nih.gov)
Signs1
Warning signs be taken seriously since early detection and then treatment could mean the difference in surviving. (ecancerinsurance.com)
Risk1
When prescribing solely for the prevention of postmenopausal osteoporosis, therapy with PREMARIN should be considered in light of other available therapies (see Boxed Warning ) and should only be considered for women at significant risk of osteoporosis. (pfizermedicalinformation.ca)
Full1
Please click here for the Full Prescribing Information, including BOXED WARNING. (imvexxyhcp.com)
Please refer to Boxed Warning for endometrial cancer, cardiovascular disorders, probable dementia, and breast cancer. (imvexxyhcp.com)
Vaginal4
The treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. (nih.gov)
Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). (pharmacyhq.com)
The REJOICE trial: a phase 3 randomized, controlled trial evaluating the safety and efficacy of a novel vaginal estradiol soft-gel capsule for symptomatic vulvar and vaginal atrophy. (imvexxyhcp.com)
ESTRING is indicated for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause. (pfizermedicalinformation.com)
PRECAUTIONS3
Adequate diagnostic measures, including directed and random endometrial sampling when indicated, should be undertaken to rule out malignancy in postmenopausal women with undiagnosed persistent or recurring abnormal genital bleeding [see Warnings and Precautions (5.2) ]. (nih.gov)
For deep vein thrombosis, the incidence rate for OSPHENA 60 mg is 2.26 per thousand women years (2 reported cases) vs. 3.15 per thousand women years (1 reported case) with placebo [see Warnings and Precautions (5.1) ]. (nih.gov)
In the clinical trials for OSPHENA (duration of treatment up to 15 months), the incidence rates of thromboembolic and hemorrhagic stroke were 1.13 and 3.39 per thousand women years, respectively in the OSPHENA 60 mg treatment group and 3.15 and 0 with placebo [see Warnings and Precautions (5.1) ]. (nih.gov)
Treatment1
Ultrapotent topical corticosteroids remain the core treatment for vulvar lichen sclerosus, although other therapies can be added, according to an expert speaking at the virtual conference on diseases of the vulva and vagina. (medscape.com)