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  • recordings
  • Due to the small size of axon collaterals and presynaptic boutons, previous electrophysiological investigations in the neocortex have been limited to patch-clamp recordings of large presynaptic structures, indirect analysis of EPSCs recorded at the soma, and calcium imaging. (jneurosci.org)
  • rats
  • The present study aimed to identify the regions that process proprioception of the jaw-closing muscles using in vivo optical imaging with a voltage-sensitive dye in rats under urethane anesthesia. (frontiersin.org)
  • In the present study, to analyze the effects of carbamazepine and gabapentin on neuronal excitation in the spinal trigeminal subnucleus caudalis (Sp5c) in the medulla oblongata, we recorded temporal changes in nociceptive afferent activity in the Sp5c of trigeminal nerve-attached brainstem slices of neonatal rats using a voltage-sensitive dye imaging technique. (biomedcentral.com)
  • Imaging was performed in 12 adult rats (Sprague-Dawley, weight 250-300 g, age 2-3 months) that were anesthetized with a mixture of ketamine (90 mg/kg, i.p. (frontiersin.org)
  • signal-to-no
  • Utilizing recent improvements in the signal-to-noise ratio of voltage-sensitive dye imaging in mouse brain slices, we demonstrate that intracortical axon collaterals and en passant presynaptic terminals of layer 5 pyramidal cells exhibit a high density of Kv1 subunit-containing ion channels, which generate a slowly inactivating K + current critically important for spike repolarization in these compartments. (jneurosci.org)
  • responses
  • (C) Superimposing eye-movements on a natural image results in sparse responses with diverse trial-to-trial spike time variability. (frontiersin.org)
  • cellular
  • However, this technique employing organic dye lacks cellular specificity and cannot be used for longitudinal studies. (jneurosci.org)
  • studies
  • We anticipate GCAMP wide-field imaging will enable longitudinal studies during plasticity paradigms or after models of CNS disease, such as stroke, where the weighting within these connectivity maps may be altered. (jneurosci.org)
  • layer
  • The optically recorded glomerular layer response was largely resistant to bath application of GABAA receptor antagonists but was sensitive to manipulations of external chloride concentration and to bath application of a stilbene derivative, 4- acetamido-4′isothiocyanatostilbene-2,2′-disulfonic acid known to block Cl- conductances. (jneurosci.org)