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Membrane PotentialsIon Channel GatingElectric ConductivityPatch-Clamp TechniquesElectrophysiologyIon ChannelsPotassium ChannelsAction PotentialsPotassiumOocytesCalciumXenopus laevisSodiumCalcium ChannelsKineticsShaker Superfamily of Potassium ChannelsBariumPotassium Channels, Voltage-GatedElectricityTetraethylammoniumElectric StimulationXenopusTetrodotoxinCesiumTetraethylammonium CompoundsNeuronsDecapodiformesModels, BiologicalPotassium Channel BlockersElectric CapacitanceChloridesCalcium Channels, L-TypeTime FactorsMicroelectrodesSodium Channel BlockersGuinea PigsLarge-Conductance Calcium-Activated Potassium ChannelsCalcium Channel BlockersRana pipiensElectric Power SuppliesBiophysicsHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsEther-A-Go-Go Potassium ChannelsCell MembraneKv1.2 Potassium ChannelElectrochemistryIon TransportBiophysical PhenomenaCyclic Nucleotide-Gated Cation ChannelsRana esculentaRana catesbeianaMathematicsChloride ChannelsElectrodesPurkinje FibersAnuraHeartCell Membrane PermeabilityModels, NeurologicalHydrogen-Ion ConcentrationLipid BilayersSpider VenomsRana temporariaHeart Conduction SystemVentricular FunctionMyocardiumPotassium Channels, Calcium-ActivatedMusclesRNA, ComplementaryScorpion VenomsDose-Response Relationship, DrugEgtazic AcidBatrachotoxinsAmbystomaAxonsBiophysical ProcessesCadmiumElectrophysiological PhenomenaElectric ImpedanceHeart VentriclesMagnesiumCationsElectromagnetic FieldsAmino Acid SequenceProtein Structure, TertiaryMolluscaConnexinsMolecular Sequence DataGap JunctionsRabbitsNifedipineRats, Sprague-DawleySarcoplasmic ReticulumElectronicsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsCalcium Channels, T-TypeMutationSinoatrial NodePotassium Channels, Inwardly RectifyingComputer Simulation
Calcium channelPotassium channelsExtracellularKineticsConformationalStimuliProteinsMembraneProcessesSubunitRelayPoreChannelsTerminalsMolecularThresholdGradientsSwitchesCellsActivationLightingSystemCurrentCapacityMicrophoneChannelDetectionSwitchBatteriesBatteryMechanismLightNoteImportantOutputValveSupportState
Calcium channel2
  • The SARS-CoV-2 envelope (E) protein forms a calcium- and voltage-activated calcium channel. (medicalwritersnewshubb.com)
  • Here we show that the voltage-gated calcium channel Ca V 1.3 and the big conductance calcium-activated potassium (BK) channel are preferentially expressed by electrosensory cells in little skate ( Leucoraja erinacea ) and functionally couple to mediate electrosensory cell membrane voltage oscillations, which are important for the detection of specific, weak electrical signals. (nature.com)
Potassium channels1
  • ROS may induce intracellular calcium increase and subsequent contraction of PASMCs via direct or indirect interactions with protein kinases, phospholipases, sarcoplasmic calcium channels, transient receptor potential channels, voltage-dependent potassium channels and L-type calcium channels, whose relevance may vary under different experimental conditions. (ersjournals.com)
Extracellular2
  • Removal of extracellular Ca2+ markedly increases the amplitude of the proctolin-evoked current and linearizes its current-voltage curve. (jneurosci.org)
  • To explore the new molecular sensors in beta cells and investigate how the sensors can be activated or regulated by extracellular stimuli. (lu.se)
Kinetics1
  • Here, we report ASAP3, a genetically encoded voltage indicator with 51% fluorescence modulation by physiological voltages, submillisecond activation kinetics, and full responsivity under two-photon excitation. (nih.gov)
Conformational2
  • Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation. (nih.gov)
  • Subsequent movement of the S4 helix from the intermediate state to the activated state then triggers conformational change of the pore from the IO state to the AO state. (elifesciences.org)
Stimuli2
  • Clusin, W. T. & Bennett, M. V. The oscillatory responses of skate electroreceptors to small voltage stimuli. (nature.com)
  • These respond to a variety of stimuli, such as voltage, chemical ligands, and mechanical/osmotic stimuli. (lu.se)
Proteins1
  • Channels made with the altered CACNA1S proteins likely activate the RYR1 channel improperly in response to certain drugs (particularly some anesthetics and a type of muscle relaxant used during surgery). (medlineplus.gov)
Membrane4
  • It is widely accepted that membrane voltage potentiates aminoglycoside activity, which is ascribed to voltage-dependent drug uptake. (elifesciences.org)
  • In this paper, we measured the response of Escherichia coli treated with aminoglycosides and discovered that the bactericidal action arises not from the downstream effects of voltage-dependent drug uptake, but rather directly from dysregulated membrane potential. (elifesciences.org)
  • Upon membrane depolarization, the KCNQ1 potassium channel opens at the intermediate (IO) and activated (AO) states of the stepwise voltage-sensing domain (VSD) activation. (elifesciences.org)
  • In this study, we confirm that T-type CaV3.2 contributes to calcium influx by initiating membrane depolarization and activating L-type CaV. (lu.se)
Processes2
  • Among numerous treatment processes, activated carbons (ACs) adsorption is widely used because of its simple design, easy accessibility, and high efficiency [ 14 ]. (hindawi.com)
  • An overabundance of calcium ions activates processes that generate heat (leading to increased body temperature) and produce excess acid (leading to acidosis). (medlineplus.gov)
Subunit1
  • It adopts the canonical structural organization of the homo-tetrameric K V superfamily, in which each subunit contains six transmembrane segments (S1-S6), with the first four (S1-S4) forming the voltage-sensing domain (VSD) and the latter two (S5-S6) folding to the pore ( Sun and MacKinnon, 2017 ). (elifesciences.org)
Relay2
  • The VAR1 Voice-Activated Relay is a DPDT relay device that is activated when an audio signal is detected at the microphone pre-amp or at 70V, 25V, or 600-ohm line level inputs. (provantage.com)
  • Hi I am trying to activate Mach3 USB Controller Output Terminals to activate a plasma from a output relay. (buildyourcnc.com)
Pore1
  • The voltage experiments showed that the E protein was most likely a voltage-gated pore regulated by electrowetting and a hydrophobic gating motif (comprising Phe20, 23, and 26 residues) located in the pore's center. (medicalwritersnewshubb.com)
Channels11
  • The first aim of the present investigation was to determine whether DCs express functional Ca2+ activated Cl- channels, their molecular identity and a possible role in DC functions. (uni-tuebingen.de)
  • voltage-gated and calcium-activated channels. (wikipedia.org)
  • Cobatoxin 1 and 2 both block the Kv1.1 K+-channels in mice and the Shaker B K+ channels in insects, which are voltage-dependent K+-channels (Selisko, 1998). (wikipedia.org)
  • Other voltage-dependent K+-channels that are blocked by Cobatoxin 1 are the Kv1.2 K+-channels in rats and Kv1.3 K+-channels in mice. (wikipedia.org)
  • Ca2 + ions activated ER-luminal channels and maintained the pores in the open state. (medicalwritersnewshubb.com)
  • Both channels exhibit unique properties compared with their mammalian orthologues that support electrosensory functions: structural adaptations in Ca V 1.3 mediate a low-voltage threshold for activation, and alterations in BK support specifically tuned voltage oscillations. (nature.com)
  • Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating. (sfu.ca)
  • Tetrodotoxin exerts its effects by blocking voltage-activated sodium channels, terminating nerve conduction and muscle action potentials, leading to progressive paralysis and, in extreme cases, to death from respiratory failure. (cdc.gov)
  • Signals transmitted by CACNA1S-containing channels turn on (activate) RYR1 channels, which then release calcium ions inside the cells. (medlineplus.gov)
  • In pancreatic β-cells, the active of voltage-gated calcium (CaV) channels play an essential role in the glucose-stimulated insulin secretion (GSIS). (lu.se)
  • We believe that with the electroencephalogram the raw data retains most of (EEG), where electrodes are the information about when ex- placed over the scalp to mea- A few channels of EEG data from actly most of the activity in the sure voltage. (lu.se)
Terminals1
  • If no voltage is output then check under the board to where the terminals are soldered. (buildyourcnc.com)
Molecular1
  • Molecular dynamic (MD) simulations were performed, and voltage-clamp electrophysiological measurements were recorded to quantify Ca2 + channel activity. (medicalwritersnewshubb.com)
Threshold2
  • Figure 2: Skate Ca V has a low voltage threshold. (nature.com)
  • Figure 3: Positively charged motif confers skate Ca V voltage threshold. (nature.com)
Gradients2
  • The hydrophobically gated ion channel activity of the viral E protein and viroporins were regulated by elevated luminal Ca2 + concentrations (0.1 mM to 1.0 mM), electrochemical gradients, pH, PTMs, ERGIC phospholipids with negative charges, and voltage applied to the membranes. (medicalwritersnewshubb.com)
  • Electrosensory cells within these ampullae can discriminate and respond to minute changes in environmental voltage gradients through an unknown mechanism. (nature.com)
Switches1
  • Knowing this I assumed that the simplest way of building the controller, would be that it switches on when the system voltage is for example 12.8V, since my batteries should never have 12.8V unless they are being charged. (allaboutcircuits.com)
Cells3
  • In the absence of voltage, aminoglycosides are taken into cells and exert bacteriostatic effects by inhibiting translation. (elifesciences.org)
  • When cells were voltage-clamped at -75 mV in the whole-cell configuration, holding currents of 50 to 300 pA associated with increased noise were consistently recorded. (aspetjournals.org)
  • Selection of edited cell clones currently relies on limiting dilution or fluorescence-activated cell sorting (FACS)-based single-cell sorting to isolate single cells. (nature.com)
Activation2
  • Activated carbons (ACs) were prepared from pomelo peels by K 2 CO 3 activation and used as an adsorbent (PAC) for the removal of Cu(II) from aqueous solutions. (hindawi.com)
  • f) Click on the account activation link to activate your account. (who.int)
Lighting5
  • Laufer Wind has successfully demonstrated its Aircraft Detection Sight Solution (ADSS), the first-ever trial against a radar-activated obstruction lighting system on a wind farm in the U.S. The Federal Aviation Administration and the Energy Department's National Renewable Energy Laboratory participated in the trial. (windsystemsmag.com)
  • Laufer Wind is a technology leader in the field of radar-activated lighting for wind farms. (windsystemsmag.com)
  • Several wind farm developments in the U.S. have recently been permitted with the expectation that they will include radar-activated lighting systems, when approved by the FAA. (windsystemsmag.com)
  • The successful trial advances efforts to bring radar-activated lighting systems to market. (windsystemsmag.com)
  • This technology is simply a smart switch that will activate the lighting when an aircraft is within three nautical miles of any part of the obstruction. (windsystemsmag.com)
System2
  • And when i charge my batteries for example at home or on my boat (where i have volt meters always connected) the system voltage quickly rises over 13V, if the batteries aren't very empty. (allaboutcircuits.com)
  • One important component in this system is the activated charcoal canister. (hella.com)
Current2
  • In voltage clamp, proctolin evokes an inward current, carried at least partially by Na+, that shows strong outward rectification. (jneurosci.org)
  • The final assembled Zn-CO2 battery has a 1.6 V output voltage at a current density of 0.063 mA/cm2, which is higher than most devices reported in the literature. (cdc.gov)
Capacity2
  • Here's a RaspPi project that collects and live-plots voltage, temperature, and battery capacity data. (nutsvolts.com)
  • Fitment Note:*** Always double check the battery voltage, capacity, terminal type, and dimensions needed before purchasing. (sears.com)
Microphone1
  • This non functioning 288 hour voice activated lighter has a built in microphone for recording audio. (deluxecctv.com)
Channel1
  • Cobatoxin 1 also blocks the IKCa1 Ca2+-activated K+-channel. (wikipedia.org)
Detection1
  • Upon detection of voltage, the tester tip glows red and beeper sounds (if activated). (fluke.com)
Switch1
Batteries3
  • I don't think i have ever measured the voltage while charging, but if i remember correctly i measured around 12.5V when the batteries are full. (allaboutcircuits.com)
  • Electrochemically activated CNT sheet as a cathode for ZN-CO2 batteries. (cdc.gov)
  • This paper presents the activated CNT sheet as a promising cathode material for Zn-CO2 batteries. (cdc.gov)
Battery1
  • The system's voltage is continually monitored through a battery sensor. (cars.com)
Mechanism1
  • The first is that the uptake mechanism, and therefore the resulting bactericidal activity, is voltage dependent ( Damper and Epstein, 1981 ). (elifesciences.org)
Light1
  • Good Earth Lighting's 2-head hardwired motion-activated security light provides safety and security by illuminating dark areas such as backyards and driveways. (goodearthlighting.com)
Note1
  • Go to the software and click on the device you want to test (mist, coolant or spindle) and note the voltage. (buildyourcnc.com)
Important2
  • The development of cheaper activated carbon is an important part of promoting its widespread use. (hindawi.com)
  • Here you will find useful basic information and important tips relating to the activated charcoal canister in vehicles. (hella.com)
Output1
Valve3
  • The timed valve is located in the connecting pipe between the intake pipe and activated charcoal canister. (hella.com)
  • As soon as the lambda control is active, the timed valve is actuated and the line between the suction pipe and activated charcoal canister is released. (hella.com)
  • The compressed air is released in short bursts via a 12V solenoid air valve to activate the zombie and lid. (makezine.com)
Support1
  • Our data support a model of voltage-induced death, and separates aminoglycoside bacteriostasis and bactericide in E. coli . (elifesciences.org)
State1
  • Senses the steady state electrostatic field produced by AC voltage through insulation without requiring contact to the bare conductor. (fluke.com)