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  • vitro and in vivo
  • As a result, developmentally expressed transcription factors implicated in neuronal identity specification are being explored for their ability to induce the development of particular neuronal subtypes in vitro and in vivo ( Amamoto and Arlotta, 2014 ). (jneurosci.org)
  • in Vitro and in Vivo Inhibitory Effects of α-Mangostin on Cholangiocarcinoma Cells and Allografts', Asian Pacific Journal of Cancer Prevention , 18(3), pp. 707-713. (waocp.org)
  • Naoki Maeda, Shinji Kamisuki, Shunya Takahashi, Hiromi Yoshida, Kengo Sakaguchi, Fumio Sugawara and Yoshiyuki Mizushina, " The In Vitro and In Vivo Inhibitory Effect of Dehydroaltenusin: A Specific Inhibitor of Mammalian DNA Polymerase α", Current Bioactive Compounds (2006) 2: 3. (eurekaselect.com)
  • In contrast, data from both in vitro and in vivo studies indicate that inhibition of UGT2B7 may potentially result in significant drug-drug interactions (DDIs), with reduced clearance via glucuronidation. (aspetjournals.org)
  • enzymes
  • Therefore, it is not surprising that members of the cathepsin family of proteases were among the first enzymes targeted in vivo by activatable fluorescent reagents [ 15 ]. (thno.org)
  • compound
  • We succeeded in chemically synthesizing dehydroaltenusin, and the compound inhibited the cell proliferation of human gastric cancer cell lines by arresting the cells at the S-phase, and preventing the incorporation of thymidine into the cells, indicating that it blocks in vivo DNA replication by inhibiting polα. (eurekaselect.com)
  • effect
  • These results suggest that the presence of the sodium-calcium exchange mechanism and the specific inhibitory effect of magnesium were indicated in human myometrium during pregnancy. (nii.ac.jp)
  • gene
  • Transcriptome profiling of Ptf1a-misexpressing cells using RNA-seq reveals that Ptf1a significantly alters pyramidal cell gene expression, upregulating numerous Ptf1a-dependent inhibitory interneuron markers and ultimately generating a gene expression profile that resembles the transcriptomes of both Ptf1a-expressing spinal interneurons and endogenous cortical interneurons. (jneurosci.org)
  • study
  • MIF-mediated signal transduction involves binding to cell-surface CD74, this study documents, in vivo, MIF- CD74 interactions at the urothelial cell surface. (hindawi.com)
  • role
  • We have been studying the role of a unique proinflammatory cytokine, macrophage migration inhibitory factor (MIF) in experimental and clinical cystitis [ 2 - 4 ]. (hindawi.com)