• Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of Vitronectin bound in the initial step. (abbkine.com)
  • VN is thought to adhere to cells with vitronectin receptors, and is involved in the immune system and blood coagulation, fibrinolytic system in blood vessels by binding to various blood coagulation factors (e.g., collagen, heparin, plasminogen activator inhibitor-1 (PAI-1), thrombin, antithrombin III complex, etc. (clontech.com)
  • Vitronectin has been implicated as a regulator of many diverse physiological processes including coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune response, cell attachment and spreading. (biovendor.com)
  • Vitronectin deficiency is associated with increased wound fibrinolysis and decreased microvascular angiogenesis in mice. (nih.gov)
  • To determine whether vitronectin may be necessary for nondevelopmental processes, we examined the response to tissue injury in vitronectin-null mice. (nih.gov)
  • This study suggests that vitronectin may have several distinct functions that are not required for normal development but are manifested in response to tissue injury. (nih.gov)
  • Moreover, the PE-deficient mutant showed a significantly decreased binding to both soluble and immobilized vitronectin. (lu.se)
  • In parallel, PE-expressing Escherichia coli bound soluble vitronectin and adhered to immobilized vitronectin compared with controls. (lu.se)
  • Cultrex® Human Vitronectin, PathClear® is a purified stromal ECM protein that has been developed, produced and qualified as a coating for cell attachment and that has been PathClear® tested. (trevigen.com)
  • Human Vitronectin, PathClear® may also be used as to supplement customized medium formulations for cell culture. (trevigen.com)
  • Cultrex® Human Vitronectin, Pathclear® is purified from human plasma and is Pathclear® certified to be free of common pathogens. (trevigen.com)
  • Vitronectin is purified from human plasma and is 0.2 μm sterile filtered. (trevigen.com)
  • Cultrex® Human Vitronectin, Pathclear® is a purified plasma extracellular matrix protein that has been developed, produced and qualified specifically for cell culture studies where the presence of pathogens may cause concern. (trevigen.com)
  • Although Cultrex® Human Vitronectin, PathClear® has been tested for the viruses above it contains human source material and therefore should be treated as potentially infectious and handled at the Biological Safety Level 2 to minimize exposure. (trevigen.com)
  • One‐step purification of vitronectin from human plasma by affinity chromatography on phage‐displayed peptides. (currentprotocols.com)
  • Novel purification of vitronectin from human plasma by heparin affinity chromatography. (currentprotocols.com)
  • The vitronectin production was further enhanced with the combination of zymosan and naïve human serum. (arvojournals.org)
  • Immunofluorescence analysis of human pluripotent markers of H1 hPSC expanded in NutriStem® V9 XF medium under a weekend-free feeding regime using Vitronectin ACF. (bioind.com)
  • Immunophenotyping analysis for human pluripotent markers of H1 hESC culture maintained in NutriStem® V9 XF medium under a weekend-free feeding regime using 0.5μg/cm 2 Vitronectin ACF at P8 and P17. (bioind.com)
  • Zanetti, Conforti, Hess, Martìn-Padura, Ghibaudi, Preissner, Dejana: Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane. (antibodies-online.com)
  • Importantly, vitronectin bound to the surface of NTHi 3655 reduced membrane attack complex-induced hemolysis. (lu.se)
  • Moreover, the PE-dependent vitronectin-binding site was located at the heparin-binding domains of vitronectin and the major vitronectin-binding domain was found in the central core of PE (aa 84-108). (lu.se)