AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation Science
Cells, CulturedModels, BiologicalCoculture TechniquesCell Culture TechniquesCell LineEpithelial CellsCell DifferentiationOrgan Culture TechniquesCell SurvivalTissue Culture TechniquesBlood-Brain BarrierDose-Response Relationship, DrugAnimal Testing AlternativesRNA, MessengerTime FactorsCell Line, TumorApoptosisEndothelial CellsEndothelium, VascularCell ProliferationReverse Transcriptase Polymerase Chain ReactionCell AdhesionSpheroids, CellularNeuronsCaco-2 CellsRats, Sprague-DawleyGene Expression RegulationCollagenAstrocytesCell MovementCell DivisionFibroblastsCell Line, TransformedTumor Cells, CulturedBlotting, WesternDisease Models, AnimalSignal TransductionMicroscopy, Electron, ScanningGene ExpressionTight JunctionsExtracellular MatrixEpitheliumCell DeathMicroscopy, ConfocalMicroscopy, ElectronCulture MediaPermeabilityElectric ImpedanceFlow CytometryMicroscopy, FluorescenceCell CommunicationImmunohistochemistryTissue EngineeringTranscytosisCattleWound HealingCell HypoxiaMice, Inbred C57BLHomogentisic AcidOchronosisL-Lactate DehydrogenaseModels, CardiovascularTransendothelial and Transepithelial MigrationHepatocytesDrug Evaluation, PreclinicalIntestinal MucosaToxicity TestsUp-RegulationCytokinesNeuroprotective AgentsAlkaptonuriaSwineTumor Necrosis Factor-alphaGelsMacrophagesEmbryonic Stem CellsBiofilmsMicroscopy, Electron, TransmissionDiazinonDiffusion Chambers, CultureBacterial AdhesionFluorescent Antibody TechniqueGene Expression ProfilingStress, MechanicalTransfectionRats, WistarStem CellsCell Transformation, NeoplasticMicroscopy, Phase-ContrastLamininColony Count, MicrobialMonocytesModels, AnimalPhenotypeAnimals, NewbornHippocampusKeratinocytesTetrazolium SaltsEnzyme InhibitorsTrophoblasts
Cardiac tissuesTissuesVivoSystemsAnimal models
Cardiac tissues3
  • Through the creation of in vitro and in silico models of discontinuous electrical propagation, data can be collected about the stress generation of sarcomeres in abnormal cardiac tissues. (escholarship.org)
  • Here, we create a model to collect contractile force data in discontinuous engineered cardiac tissues in vitro and confirm theoretical predictions about the effect of discontinuity on stress generation. (escholarship.org)
  • produced in vitro vascularized cardiac tissues with perfusable blood vessels by overlaying additional triple-layer cell sheets made by NRCMs cocultured with endothelial cells. (encyclopedia.pub)
Tissues1
  • By acting as a more sophisticated in vitro approximation of complex tissues than standard cell culture, they provide the potential as an alternative to animal models for drug development and toxin testing. (wikipedia.org)
Vivo3
  • 3) modeling organ-level physiology and disease in vitro/ex vivo, and 4) adding high precision and tunability of microfluidic devices. (wikipedia.org)
  • Organotypic brain slices are an in vitro model that replicates in vivo physiology with additional throughput and optical benefits, thus pairing well with microfluidic devices. (wikipedia.org)
  • The benefits of this system have been analyzed in vivo in murine animal models of MI showing improvements in cell survival, cardiac function and tissue remodeling [ 5 ] . (encyclopedia.pub)
Systems1
Animal models1