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Echinococcus granulosusEchinococcusEchinococcosisEchinococcus multilocularisAnticestodal AgentsEchinococcosis, PulmonaryEchinococcosis, HepaticDNA, HelminthAlbendazoleAntigens, HelminthMebendazoleAntibodies, HelminthCamelsHelminth ProteinsAnthelminticsCyst FluidSheep DiseasesAntiplatyhelmintic AgentsDog DiseasesCestode InfectionsPraziquantelCestodaTaeniaTibetArecolineFoxesSheepTaeniasisDogsAzerbaijanZoonosesSerologic TestsCystsPeruEndemic DiseasesKyrgyzstanVaccinesGoatsEnzyme-Linked Immunosorbent AssayHost-Parasite Interactions

MultilocularisTapeworm Echinococcus granulosusAlbendazoleParasiticSensu strictoProtoscolecesProtoscolicesCysticGenusHydatidAntibodiesLarvalCystVivoSchistosomaEchinococcosisEvaluationApoptosisCultivationInfection2021ImmunologicalAdultCultureActivityStudyPRODUCTION

Multilocularis7

• It has also been investigated in human tapeworms such as Echinococcus multilocularis and E. granulosus metacestodes that genistein and its derivatives, Rm6423 and Rm6426, are potent cestocides. (wikipedia.org)
• Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are zoonotic infections caused by the larval stages (metacestodes) of parasitic cestodes Echinococcus granulosus and E. multilocularis [ 15 , 17 , 52 ]. (parasite-journal.org)
• The diagnosis of alveolar echinococcosis relies on imaging and may be confirmed with specific serology and/or molecular identification of the parasite Echinococcus multilocularis in the lesions. (medscape.com)
• Echinococcus multilocularis is the causative agent of human hepatic alveolar echinococcosis (AE). (biomedcentral.com)
• We investigated the role of Echinococcus multilocularis (Echinococcus genus) PSCs in hepatic fibrosis by examining structural changes and measuring hepatic fibrosis-related protein levels in cocultures of PSCs and human HSCs. (biomedcentral.com)
• Currently, four species are recognized within the genus Echinococcus: E. granulosus (which causes cystic disease), E. multilocularis (which causes alveolar disease), E. vogeli (which causes polycystic disease), and E. oligarthrus (which causes polycystic disease). (med-chem.com)
• NT005 trade name] is indicated for the treatment of Echinococcus multilocularis and E. granulosus infections before or after surgery or where surgery is not suitable. (who.int)

Tapeworm Echinococcus granulosus3

• Hydatid bone disease is a zoonotic parasitic infection that is caused primarily by the tapeworm Echinococcus granulosus, and it continues to be a major public health concern in pastoral regions. (bvsalud.org)
• The causative agent is the tapeworm Echinococcus granulosus, whose adult stage takes place in the small intestine of definitive hosts (dogs) and the development of the larval stage occurs mainly in the liver and lung of intermediate hosts such as sheep. (edu.pe)
• For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus . (drugbank.com)

Albendazole5

• methylcarbamates derivatives (BZD) were proved to be effective against E. granulosus , and since Cystic echinococcosis (CE) caused by the then, many investigators have used albendazole metacestode (larval) stage of Echinococcus (ABZ) and mebendazole (MBZ) for the treatment granulosus ( E. granulosus ) is still an important of human hydatidosis (Teggi et al 1993). (medicpdf.com)
• its metabolite, albendazole-sulphoxide (ABZSO) Thirty mice were inoculated with protoscolices was shown to be an active anthelmintic agent of E. granulosus and divided into 5 groups. (medicpdf.com)
• In vitro effects of albendazole sulfoxide and praziquantel against Taenia solium and Taenia crassiceps cysts. (lookformedical.com)
• We investigated the minimum exposure times of prazicuantel (PZQ) and albendazole sulfoxide (ABZSO) required for their activities against Taenia cysts in vitro as well as the 50 and 99% effective concentrations. (lookformedical.com)
• [ 42 ] When surgery cannot be avoided, presurgical use of albendazole in echinococcus infestations reduced risk of recurrence and/or facilitated surgery by reducing intracystic pressure. (medscape.com)

Parasitic1

• Parasitic modulation of the immune response allows E. granulosus to persist in intermediate hosts. (ac.be)

Sensu stricto2

• MicroRNA-365 promotes apoptosis in human melanoma cell A375 treated with hydatid cyst fluid of Echinococcus granulosus sensu stricto. (physiciansweekly.com)
• The fertile/infertile HCF was aspirated from liver of infected sheep and in terms of molecular taxonomy was identified as G1 genotype of Echinococcus granulosus sensu stricto. (physiciansweekly.com)

Protoscoleces1

• Therefore imnunoprotección was evaluated against E.granulosus using surface antigens as membrane proteins and metabolic products of excretion-secretion protoscoleces and adult worms. (edu.pe)

Protoscolices1

• 2003). Both ABZ and ABZSO have been prophylactic groups, just after challenge with shown to be active against protoscolices of E. protoscolices, received 150 mg/kg BW /day granulosus in in vitro culture systems. (medicpdf.com)

Cystic1

• Human cystic echinococcosis, an endemic zoonosis in Algeria, is caused by larvae of the cestode Echinococcus granulosus. (ac.be)

Genus2

• Echinococci are platyhelminths of the cestode genus. (medscape.com)
• Hydatidosis or hydatid cyst is a prevalent zoonosis all over the world due to larval forms of the tapeworm of the genus Echinococcus. (bvsalud.org)

Hydatid2

• Previous in vitro and in vivo immunological studies have shown differences in host immune responses according to the status and location of the hydatid cysts in the body. (ac.be)
• Hydatid disease caused by E. granulosus is a zoonosis of major public health concern throughout Latin America, particularly in the Andean and South Cone regions. (med-chem.com)

Antibodies1

• A comparative study of different immunoassays to detect specific antibodies to Echinococcus spp. (uitm.edu.my)

Larval1

• El agente causante es el céstodo Echinococcus granulosus, cuyo estadio adulto se desarrolla en el intestino delgado de hospederos definitivos (caninos) y el desarrollo del estadio larval se presenta principalmente en el hígado y pulmón de hospederos intermediarios como el ganado ovino. (edu.pe)

Cyst2

• Effect of mebendazole and praziquantel on glucosephosphate isomerase and glyceraldehydephosphate dehydrogenase in Echinococcus granulosus cyst wall harbored in mice. (lookformedical.com)
• AIM: To study effects of antihydatid drugs on glucosephosphate isomerase (GPI) and glyceraldehydephosphate dehydrogenase (GAPDH) in Echinococcus granulosus cyst wall. (lookformedical.com)

Vivo2

• These findings provide new insights into the use of Echinococcus HCF-derived metabolites in the design of drug therapies and in vivo tumor cell vaccine to combat melanoma progression. (physiciansweekly.com)
• Alternative activation of macrophages by IL-4 in vitro was described as an opposite phenotype of classically activated macrophages, but the in vivo reality is much more complex. (hindawi.com)

Schistosoma1

• Acquisition of human antigens by Schistosoma mansoni during cultivation in vitro. (health.mil)

Echinococcosis1

• A recent consensus on the terminology in the field of echinococcosis has fixed the names of the diseases, the various species of Echinococcus involved and several terms to be used in the scientific literature on the subject. (medscape.com)

Evaluation1

• Subsequently adhesion performs a basic function in in vitro evaluation. (gentaur-online.com)

Apoptosis1

• However, it remains unknown, how miR-365 plays a pivotal role in inducing apoptosis in HCF-treated cancer cells in vitro. (physiciansweekly.com)

Cultivation1

• Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. (research.com)

Infection1

• Echinococcus granulosus is the most frequent form of echinococcal infection in humans. (bvsalud.org)

20211

• 2021) Echinococcus shiquicus in Qinghai-Tibet plateau: population structure and confirmation of additional endemic areas. (chvst.org.cn)

Immunological1

• Our data suggest that rFg14-3-3e protein can influence various cellular and immunological functions of goat PBMCs in vitro and may be involved in mediating F. gigantica pathogenesis. (biomedcentral.com)

Adult1

• The adult worms of E. granulosus are very small (3 to 6 mm long) and consist of a scolex, neck, and only a single proglottid at each stage of development (immature, mature, and gravid). (med-chem.com)

Culture1

• Membrane proteins were obtained by extraction with Triton x-114 and the products of excretion/secretion (E/S) obtained by in vitro culture (Medium HAM F12). (edu.pe)

Activity1

• Antitrichomonal activity of nanoemulsion of carvacrol on Trichomonas galline: formulation development and in vitro characterization. (ac.ir)

Study1

• The study of interactions between RCD and Echinococcus spp. (parasite-journal.org)

PRODUCTION2

• In vitro peripheral blood mononuclear cells [PBMC] proliferation and IFN- gamma production were assessed in a limited number of healthy adults vaccinated with a commercial acellular pertussis vaccine in response to all purified FHA fragments by H3-Thymidine incorporation and ELISA, respectively. (bvsalud.org)
• All three recombinant fragments together with a commercial native FHA were able to induce in vitro PBMC proliferation and IFN- gamma production. (bvsalud.org)