EndodermNodal Signaling LigandsSOX Transcription FactorsEmbryonic InductionCell DifferentiationSOXF Transcription FactorsEmbryonic Stem CellsHepatocyte Nuclear Factor 3-betaNodal ProteinGene Expression Regulation, DevelopmentalActivinsMesodermCell LineagePrimitive StreakGastrulaGerm LayersEmbryo, MammalianCells, CulturedHomeodomain ProteinsEmbryoid BodiesTranscription FactorsHMGB ProteinsStem CellsDigestive SystemIn Situ HybridizationBody PatterningCell LineCell Culture TechniquesSignal TransductionFibroblast Growth Factor 4MorphogenesisPluripotent Stem CellsGastrulationDNA-Binding ProteinsWnt3 ProteinReverse Transcriptase Polymerase Chain ReactionRNA, MessengerGene ExpressionTrans-ActivatorsTretinoinGene Expression ProfilingEmbryonic DevelopmentEmbryonic and Fetal DevelopmentMice, TransgenicEnzyme InductionGene Expression RegulationFlow CytometryHorseradish PeroxidasePancreasMolecular Sequence DataProsencephalonCulture Media, Serum-FreeTeratomaBiological MarkersBase SequenceHematopoietic Stem CellsHepatocytesMice, Inbred C57BLCell DivisionCell ProliferationTransforming Growth Factor betaPhenotypeMice, KnockoutTime FactorsImmunohistochemistryTranscription, GeneticEctodermNuclear ProteinsPromoter Regions, GeneticMesenchymal Stromal CellsYolk SacChimeraEmbryo, NonmammalianTumor Cells, CulturedHematopoiesisOctamer Transcription Factor-3GATA6 Transcription FactorOsteogenesisReceptor, Platelet-Derived Growth Factor alphaNeuronsBone Marrow CellsMonocytesVisceraErythropoiesisInduced Pluripotent Stem CellsModels, BiologicalApoptosisBlastocystBlotting, WesternTransfectionOsteoblastsCoculture TechniquesDNA PrimersAdipogenesisGATA5 Transcription FactorMacrophagesAmino Acid SequenceChick EmbryoCell SeparationBasic Helix-Loop-Helix Transcription Factors