Cell Migration AssaysCell Migration Assays, MacrophageCell MovementCell Migration Assays, LeukocyteCell ProliferationCell Line, TumorCells, CulturedSignal TransductionCell AdhesionCell Migration InhibitionLeukocytesLeukocyte RollingChemotaxis, LeukocyteChemotaxisWound HealingNeoplasm InvasivenessEndothelial CellsRNA, Small InterferingCell LineMice, Inbred C57BLLeukocyte CountFocal AdhesionsFibronectinsIntegrinsBlotting, WesternChemokine CXCL12PhosphorylationActinsEndothelium, VascularNeutrophilsReceptors, CXCR4Animal MigrationPseudopodiaLamininRNA InterferenceCell Adhesion MoleculesTransfectionReverse Transcriptase Polymerase Chain ReactionMolecular Sequence Datarac1 GTP-Binding ProteinRNA, MessengerForeign-Body MigrationGene Knockdown TechniquesAntigens, CD29Focal Adhesion Protein-Tyrosine KinasesMice, KnockoutMatrix Metalloproteinase 9FibroblastsGene Expression Regulation, NeoplasticProtein BindingExtracellular MatrixFlow CytometryTumor Cells, CulturedEpithelial CellsTime FactorsCell PolarityImmunohistochemistryAmino Acid SequenceUp-RegulationNeovascularization, PhysiologicDose-Response Relationship, DrugCytoskeletonNeoplasm MetastasisDiffusion Chambers, CultureRecombinant ProteinsMicroscopy, FluorescenceNeovascularization, PathologicEnzyme ActivationPaxillinChemokines, CXCCell DivisionMatrix Metalloproteinase 2Collagenrac GTP-Binding ProteinsCell Surface ExtensionsCadherinsEpithelium, CornealCell DifferentiationEnzyme InhibitorsPhosphatidylinositol 3-KinasesChemokinesDown-RegulationModels, BiologicalVascular Endothelial Growth Factor AAntigens, CDMembrane ProteinsUmbilical VeinsGene Expression RegulationMonocytesVitronectinDisease Models, AnimalCell SurvivalPlatelet-Derived Growth Factorrho GTP-Binding ProteinsMyocytes, Smooth MuscleMutationGene ExpressionrhoA GTP-Binding ProteinProto-Oncogene Proteins c-aktMicroscopy, Video