Neovascularization, PhysiologicNeovascularization, PathologicEndothelial CellsEndothelium, VascularAngiogenesis InhibitorsVascular Endothelial Growth Factor AAngiogenesis Inducing AgentsCapillariesCell MovementUmbilical VeinsCells, CulturedVascular Endothelial Growth FactorsFibroblast Growth Factor 2Endothelial Growth FactorsVascular Endothelial Growth Factor Receptor-2LymphokinesCell ProliferationAllantoisChorioallantoic MembraneDrug CombinationsLamininHuman Umbilical Vein Endothelial CellsCell DivisionCollagenCell Line, TumorSignal TransductionMice, NudeCoculture TechniquesBiological AssayCulture Media, ConditionedCell LineChick EmbryoCattlePhosphorylationProteoglycansMatrix Metalloproteinase 2Mice, Inbred C57BLXenograft Model Antitumor AssaysBlotting, WesternRNA, MessengerApoptosisReverse Transcriptase Polymerase Chain ReactionDose-Response Relationship, DrugMice, Inbred BALB CAngiogenic ProteinsAngiogenesis Modulating AgentsRecombinant ProteinsBlood VesselsAntigens, CD31Receptors, Vascular Endothelial Growth FactorCorneal NeovascularizationAngiopoietin-2Angiopoietin-1IschemiaThrombospondin 1Receptor, TIE-2ChorionHindlimbMicrovesselsHypoxia-Inducible Factor 1, alpha SubunitNeoplasmsVascular Endothelial Growth Factor Receptor-1ImmunohistochemistryEndostatinsMicrocirculationIntegrin alphaVbeta3Neoplasm TransplantationRetinal NeovascularizationIntercellular Signaling Peptides and ProteinsCarcinoma, Lewis LungDisease Models, AnimalWound HealingCyclohexanesAngiostatinsPericytesTransplantation, HeterologousReceptors, Growth FactorCell HypoxiaRetinal VesselsGene Expression Regulation, NeoplasticMice, KnockoutLymphangiogenesisAngiopoietinsNeoplasms, ExperimentalUp-RegulationReceptor Protein-Tyrosine KinasesMice, SCIDAngiostatic ProteinsCorneaNeoplasm InvasivenessTumor Cells, CulturedMatrix Metalloproteinase 9Neoplasm MetastasisAntineoplastic AgentsProto-Oncogene Proteins c-aktRNA, Small InterferingThrombospondinsAnoxiaHypoxia-Inducible Factor 1Collagen Type XVIII