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  • toxicology
  • We offer an extensive suite of in vitro and alternative toxicology assays to assess product safety that can quantify the toxic potential and other effects of pharmaceutical products on different primary cells and tissues. (mbresearch.com)
  • These in vitro and alternative assays are utilized to more rapidly identify potential safety and developmental problems which are often discovered in more costly animal safety and toxicology evaluations. (mbresearch.com)
  • Over 25 Years of In Vitro Toxicology Testing Experience. (mbresearch.com)
  • The primary focus of Applied In Vitro Toxicology is on the alternative testing methods and their applications of new cell- and tissue-based methods for predicting adverse effects in the pharmaceutical, veterinary, horticultural, chemical, and personal care industries. (liebertpub.com)
  • Applied In Vitro Toxicology promotes the application of in vitro science to understand adverse events. (liebertpub.com)
  • Appropriate use of the English language is a requirement for review and publication in Applied In Vitro Toxicology . (liebertpub.com)
  • Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. (elsevier.com)
  • the application of genomics , transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. (elsevier.com)
  • Toxicology in Vitro discourages papers that record reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized. (elsevier.com)
  • Most toxicologists believe that in vitro toxicity testing methods can be more useful, more time and cost-effective than toxicology studies in living animals (which are termed in vivo or "in life" methods). (wikipedia.org)
  • Toxicology in Vitro is a bimonthly peer-reviewed scientific journal covering in vitro toxicology. (wikipedia.org)
  • It is published by Elsevier and an official journal of the European Society of Toxicology in Vitro and affiliated with the American Association for Cellular and Computational Toxicology. (wikipedia.org)
  • vivo
  • Among them, in vitro assays have been quantitative and expeditious as initial approximations that warrant further confirmation in vivo . (news-medical.net)
  • Furthermore, in vivo interaction between endothelial cells and other cells types (such as fibroblasts, pericytes and macrophages) is cumbersome to translate and simulate in vitro . (news-medical.net)
  • I have not tried in-vivo transformation yet, but considering my in-vitro results I would expect the same results. (bio.net)
  • In contrast to in vitro experiments, in vivo studies are those conducted in animals, including humans, and whole plants. (wikipedia.org)
  • Viruses, which only replicate in living cells, are studied in the laboratory in cell or tissue culture, and many animal virologists refer to such work as being in vitro to distinguish it from in vivo work in whole animals. (wikipedia.org)
  • However, the extrapolation from in vitro to in vivo requires some careful consideration and is an active research area. (wikipedia.org)
  • A hybrid approach between in vitro and in vivo has recently been used, called in situ, in which the organism is put under terminal anesthesia, and in vitro tests are performed with the muscle still attached to the organism. (wikipedia.org)
  • maturation
  • In vitro maturation is when the ova are extracted and then matured in a laboratory (instead of in the mother's body) before they are fertilized. (infoplease.com)
  • Through in vitro maturation, folliculogenesis and latter parts of oogenesis are being mimicked outside of the ovaries- trying to recreate the conditions for these processes. (wikipedia.org)
  • assay
  • To determine the possible sensitizing potential of a test article in vitro as an alternative assay for animal based test systems. (mbresearch.com)
  • This review also discusses our own 3-D angiogenesis assay and some of the in vitro results from our lab as they relate to therapeutic neovascularization and tissue engineering of vascular grafts. (springer.com)
  • The colorimetric MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2Htetrazolium) in vitro assay is an updated version of the validated MTT method, MTS assay has the advantage of being soluble. (wikipedia.org)
  • Yanow
  • Commending Vitro as "a versatile vocalist who is not afraid to take chances," Yanow also cites the contributions of both pianist/musical director Kenny Werner and a roster of guest artists including "altoist Gary Bartz, trumpeter Tim Hagans, bassist Christian McBride and drummer Elvin Jones. (wikipedia.org)
  • tissues
  • Manuscripts containing experiments done solely in animals or in which tissues used in vitro were obtained from animals in not consistent with the primary focus of the journal. (liebertpub.com)
  • In vitro diagnostics refers to a wide range of medical and veterinary laboratory tests that are used to diagnose diseases and monitor the clinical status of patients using samples of blood, cells, or other tissues obtained from a patient. (wikipedia.org)
  • In vitro models for calcification may refer to systems that have been developed in order to reproduce, in the best possible way, the calcification process that tissues or biomaterials undergo inside the body. (wikipedia.org)
  • 1978
  • In 1968 Vitro was acquired by Automation Industries Inc and renamed Vitro Engineering Corp. In 1978 Automation Industries and its Vitro subsidiary were acquired by General Cable Corp, which renamed the new company GK Technologies. (wikipedia.org)
  • 1981
  • In 1981 GK Technologies (including Vitro) was acquired by the Penn Central Corporation. (wikipedia.org)
  • After a major fire destroyed a large part of the Vitra production facilities in Weil am Rhein in 1981, British architect Nicholas Grimshaw was commissioned to design new factory buildings and develop a master plan for the company premises. (wikipedia.org)
  • Diagnostics
  • SMi is proud to announce the launch of their In-Vitro Diagnostics (IVD) event to London in 2017! (smi-online.co.uk)
  • SMi's In-Vitro Diagnostics (IVD) will prepare you for the challenging times ahead and how to comply with regulatory requirements to ensure direct access to market ensuring the continued growing demand for use and innovation of IVDs over the next decade and beyond. (smi-online.co.uk)
  • 1992
  • By the early 1990s Penn Central had begun to focus on financial services and in 1992 announced it was divesting Vitro. (wikipedia.org)
  • Sterility
  • The In Vitroes were first farmed by the In Vitro Authority to fill the labor force gap after the population of Earth was decimated by a sterility-causing plague. (wikipedia.org)
  • molecules
  • In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. (wikipedia.org)
  • cDNA molecules are DNA copies of mRNA molecules, produced in vitro by action of the enzyme reverse transcriptase. (wikipedia.org)
  • Manuscripts
  • The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals). (elsevier.com)
  • refers
  • Thus, In Vitro refers to the race not only being conceived in a laboratory, but also artificially gestated in glass and metal cylinders, to be "born" as young adults. (wikipedia.org)
  • experiments
  • however, results obtained from in vitro experiments may not fully or accurately predict the effects on a whole organism. (wikipedia.org)
  • systems
  • Vitro merged with Tracor Applied Sciences to form Tracor Systems Technologies, Tracor's largest subsidiary. (wikipedia.org)
  • There are substantial activities in using in vitro systems to advance mechanistic understanding of toxicant activities, and the use of human cells and tissue to define human-specific toxic effects. (wikipedia.org)
  • A number of kinetic models have been proposed to take care of these non-specific bindings taking place in these in vitro systems. (wikipedia.org)
  • therapeutic
  • In vitro (literally 'in glass') testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as therapeutic drugs, agricultural chemicals and food additives. (wikipedia.org)
  • development
  • In 1950 Vitro acquired the Kellex Corporation, a company involved in the development of the nuclear bomb. (wikipedia.org)
  • In vitro calcification models have been used in medical implant development to evaluate the calcification potential of the medical device or tissue. (wikipedia.org)
  • humans
  • In vitro muscle testing is almost never used in humans, with the exception of small sections of muscle removed via biopsy or while undergoing surgery for other ailments. (wikipedia.org)
  • relate
  • In vitro muscle testing has provided the bulk of scientific knowledge on muscle structure and physiology, as well as how both relate to organismal performance. (wikipedia.org)
  • review
  • A contemporaneous review by Washington Post music critic Mike Joyce is similarly impressed: A less talented singer might find herself intimidated by the company Vitro keeps on her new album. (wikipedia.org)
  • known
  • Recombinant DNA is also known as in vitro recombination. (wikipedia.org)
  • Vitra is also known for the works of notable architects that make up its premises in Weil am Rhein, Germany, in particular the Vitra Design Museum. (wikipedia.org)
  • however
  • However, the use of animal data to confirm or validate a new in vitro approach would be appropriate. (liebertpub.com)
  • however they can share DNA with another In Vitro created from the same batch of constructed chromosomes, which would make two such individuals siblings. (wikipedia.org)
  • Inspired by his acquaintance with Frank Gehry in the mid-1980s, however, Vitra departed from Grimshaw's plan for a unified corporate project. (wikipedia.org)
  • Glass
  • Vitro is the largest glass producer in Mexico and one of the world's main organizations in its industry. (wikipedia.org)
  • Years
  • Vitro worked for two years in Houston's Green Room with her group "Roseanna with Strings and Things" hosting a radio show on KUHF-FM. (wikipedia.org)
  • Over the years, Vitra accumulated a growing collection of chairs and other furniture. (wikipedia.org)
  • cells
  • These in vitro techniques include utilizing cell or tissue cultures, isolated cells. (elsevier.com)
  • These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. (elsevier.com)
  • types
  • Broadly speaking, there are two different types of in vitro studies depending on the type system developed to perform the experiment. (wikipedia.org)
  • models
  • In vitro calcification models can be categorized according to the level of representation of the physiological conditions, as static culture, constant supersaturation, and dynamic models. (wikipedia.org)
  • animal
  • In many cases the in vitro tests are better than animal tests because they can be used to develop safer products. (wikipedia.org)
  • factory
  • The thought of beef grown in the lab may turn your stomach, but in vitro meat would avoid many of the downsides of factory farming, most notably pollution: in the United States, livestock produce 1.4 billion tons of waste each year. (nytimes.com)
  • study
  • In vitro work simplifies the system under study, so the investigator can focus on a small number of components. (wikipedia.org)
  • done
  • In vitro studies permit a species-specific, simpler, more convenient, and more detailed analysis than can be done with the whole organism. (wikipedia.org)
  • In vitro muscle testing can be done on any scale of muscle organization - entire groups of muscles (provided they share a common insertion or origin, as in the human quadriceps), a single muscle, a "bundle" of muscle fibers, a single muscle fiber, a single myofibril, a single sarcomere, or even a half-sarcomere. (wikipedia.org)
  • human
  • Just as studies in whole animals more and more replace human trials, so are in vitro studies replacing studies in whole animals. (wikipedia.org)