• This report examines selected AI-based initiatives, collaborations, and tests in various in vitro diagnostic (IVD) market segments. (prnewswire.com)
  • It is in-vitro diagnostic equipment which is applied for quantitative analysis of blood cells in laboratories. (environmental-expert.com)
  • Top companies in the in-vitro diagnostic market are strategically partnering and collaborating with other companies to broaden their products, technologies and services. (medindia.net)
  • Automating in-vitro diagnostic devices helps the healthcare industry to drastically reduce potential errors and more accurately help detect infection, diagnose medical conditions, prevent disease, and monitor drug therapies. (cognex.com)
  • Elderly population base suffering from chronic conditions will have high preference for laboratory diagnostic services that should escalate in-vitro diagnostic services market growth. (openpr.com)
  • Improvements and automations in diagnostic services have enabled genetic disease detection at molecular level thereby will positively impact on the in-vitro diagnostic services industry growth. (openpr.com)
  • Hospitals segment of in-vitro diagnostic services industry held largest revenue share of 30.6% in 2017 and should expand enormously in foreseeable future due to rising number of hospital admissions demanding accurate diagnosis and critical monitoring. (openpr.com)
  • U.S. in-vitro diagnostic services market will grow at 5.6% over the forecast timeframe and high growth of this segment can be attributed to growing number of initiatives taken by the organizations that will create awareness regarding availability of services thereby, should augment business growth. (openpr.com)
  • In-vitro diagnostic services market is highly regulated ensuring improvised quality of diagnostic services escalating preference for services over the upcoming years. (openpr.com)
  • China in-vitro diagnostic services market was valued at USD 2.2 billion in 2017, as a result of the increasing incidences of cancer. (openpr.com)
  • A method for performing multiple, simultaneous in vitro diagnostic tests is provided. (google.com)
  • A journal of the Society for In Vitro Biology (SIVB). (springer.com)
  • The Society for In Vitro Biology (SIVB) was founded in 1946 as the Tissue Culture Association to foster the exchange of knowledge of in vitro biology of cells, tissues, and organs from both plants and animals (including humans). (springer.com)
  • Each year, four issues from the Society for In Vitro Biology (SIVB) cover cellular, molecular and developmental biology research using in vitro grown or maintained organs, tissues or cells derived from plants. (springer.com)
  • Founded in 1965, In Vitro Cellular & Developmental Biology - Animal remains unique in its focus on in vitro biology in animals. (springer.com)
  • This peer-reviewed journal reports results of research in cellular, molecular, and developmental biology that employ or are relevant to organs, tissue, tumors, and cells in vitro. (springer.com)
  • With its high-caliber original research and reviews, In Vitro Cellular & Developmental Biology - Animal benefits everyone who needs to keep up-to-date on the latest developments and state-of-the-art research in animal cell and tissue culture and biotechnology from around the world. (springer.com)
  • Founded in 1965, In Vitro Cellular & Developmental Biology - Plant is the only journal devoted solely to worldwide coverage of in vitro biology in plants. (springer.com)
  • 3), successfully matured immature oocytes in vitro, fertilized them and then transferred the cleaved embryos leading to a viable pregnancy. (gfmer.ch)
  • A number of studies have been performed on chromosomal abnormalities in oocytes, while embryo culture studies have been able to improve the development of embryos to the blastocyst stage in vitro (17, Sakkas, unpublished data). (gfmer.ch)
  • NORMAL and neoplastic mammalian cells cultivated in vitro retain a number of functions that characterize their cellular origin, even after extensive passage 1 . (nature.com)
  • Cellular ageing in vitro . (els.net)
  • SMi is proud to announce the launch of their In-Vitro Diagnostics (IVD) event to London in 2017! (smi-online.co.uk)
  • The Japan In Vitro Diagnostics Devices Industry Market Research Report 2017 is a professional and in-depth study on the current state of the In Vitro Diagnostics Devices industry. (mynewsdesk.com)
  • NEW YORK , July 26, 2017 /PRNewswire/ -- In-vitro diagnostics (IVD) are used to detect diseases, infections, and conditions and also monitor a person's state of health and therapeutic procedures by examining specimens derived from the human body such as tissue, blood, stools, urine and the other body fluids. (medindia.net)
  • There are substantial activities in using in vitro systems to advance mechanistic understanding of toxicant activities, and the use of human cells and tissue to define human-specific toxic effects. (wikipedia.org)
  • Early in vitro toxicology studies provide advanced mechanistic understanding of toxicant activities at the fundamental level of the cell, without the interplay of complex physiological effects at the whole organism level, allowing researchers to isolate and better understand toxicity in very specific tissue types or models. (intertek.com)
  • Global In Vitro Diagnostics (IVD) Market 2016 Investment. (mynewsdesk.com)
  • In vitro maturation is when the ova are extracted and then matured in a laboratory (instead of in the mother's body) before they are fertilized. (infoplease.com)
  • In vitro synthesis of single-stranded RNA molecules is a widely used laboratory procedure that is critical to RNA research, as well as to RNA biopharmaceuticals. (neb.com)
  • in vitro Describing biological processes that are made to occur outside the living body, in laboratory apparatus (literally 'in glass', i.e. in a test tube). (encyclopedia.com)
  • This transeuropean research consortium aims to improve the scientific and technical basis for the evaluation of oculotoxicity in vitro and to replace laboratory animal testing by cell culture techniques. (europa.eu)
  • In-vitro meat is 'made in the laboratory' meat - it's real meat but grown in 'vats' rather than on animals. (marginalrevolution.com)
  • According to the National Toxicology Program, "the preponderance of evidence" from laboratory "in vitro" studies indicate that fluoride is a mutagenic compound. (fluoridealert.org)
  • The colorimetric MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2Htetrazolium) in vitro assay is an updated version of the validated MTT method, MTS assay has the advantage of being soluble. (wikipedia.org)
  • This review also discusses our own 3-D angiogenesis assay and some of the in vitro results from our lab as they relate to therapeutic neovascularization and tissue engineering of vascular grafts. (springer.com)
  • With experience in assay development, method transfer and method validation, Intertek can support your in vitro toxicology screening requirements to help reduce risk and provide critical data to enable more informed decision making. (intertek.com)
  • In this study, researchers will "calibrate" responses in the Ames' assay and the in vitro Pig-a assay to in vivo mutagenicity in the rat Pig-a assay. (fda.gov)
  • The goal is to assess whether or not animal and human mutagenic responses can be estimated from the Ames' assay and in vitro Pig-a responses. (fda.gov)
  • In vitro toxicity testing is the scientific analysis of the effects of toxic chemical substances on cultured bacteria or mammalian cells. (wikipedia.org)
  • Most toxicologists believe that in vitro toxicity testing methods can be more useful, more time and cost-effective than toxicology studies in living animals (which are termed in vivo or "in life" methods). (wikipedia.org)
  • SRI is a leader in the development and application of in vitro models for ADMET evaluations (ADMET: Absorption, Distribution, Metabolism, Excretion, and Toxicity). (sri.com)
  • The aim of the proposed project is to develop a standardised in vitro test battery, based on sensitive markers for detection of eye toxicity. (europa.eu)
  • The evolution and advancement is leading to introduction of new technologies that can better predict toxicity levels and translate in vitro results into significant in vivo effects. (pitchengine.com)
  • The increasing focus on detection of toxicity in earlier stages of development is leading to persistent requirements for human cell-based in vitro models. (pitchengine.com)
  • Geographic analysis reveals that Europe commanded the largest share of the global in vitro toxicity testing market in 2013. (pitchengine.com)
  • Globally, the market will be driven by increasing acceptance of in vitro toxicity testing methods by regulatory authorities as alternatives to in vivo testing. (pitchengine.com)
  • In vitro toxicology studies can help minimise liabilities associated with late-stage failure in the drug discovery process. (intertek.com)
  • As such, novel, clinically relevant models of angiogenesis in vitro are crucial to the understanding of angiogenic processes. (springer.com)
  • Folkman J, Haudenschild C. Angiogenesis in vitro. (springer.com)
  • She received her bachelor's degree in Microbiology from the State University of New York and is an In Vitro Cell Biology Fellow, W. Alton Jones Cell Science Center in Lake Placid, NY. (corning.com)
  • Manuscripts containing experiments done solely in animals or in which tissues used in vitro were obtained from animals in not consistent with the primary focus of the journal. (liebertpub.com)
  • Since their establishment [ 3 - 5 ], iPS cells have been used to make in vitro disease models because of the difficulty in using a patient's cells or tissues, especially from the heart [ 6 - 9 ]. (hindawi.com)
  • The Latin term in vitro , meaning "in glass", is used because early biological experiments involving cultivation of tissues outside the living organism were carried out in glass containers, such as beakers, test tubes, or Petri dishes. (wikipedia.org)
  • Today, the scientific term "in vitro" is used to refer to any biological procedure that is performed outside the organism in which it would normally have occurred, to distinguish it from an in vivo procedure (such as in vivo fertilisation ), where the tissue remains inside the living organism in which it is normally found. (wikipedia.org)
  • The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions and responsiveness to inducers are retained either for a few days or several weeks depending on culture conditions. (nih.gov)
  • These in vitro techniques include utilizing cell or tissue cultures, isolated cells. (elsevier.com)
  • These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. (elsevier.com)
  • Although cardiac stem cells have advantage for in vivo regenerative medicine [ 13 , 14 ], heterogeneity was observed in long-term cultures in our in vitro cultures [ 15 ]. (hindawi.com)
  • to propose an in vitro test battery using standardised eye cell cultures. (europa.eu)
  • An SLAS Discovery original research report entitled "In Vitro Tissue Microarrays for Quick and Efficient Spheroid Characterization" describes a new technology that bridges the gap between clinical pathology assessment, high-content analysis and 3D cell cultures. (eurekalert.org)
  • Along with organ-on-a-chip models these in vitro cultures are promising increased physiological relevance and therapeutic predictivity in both safety and efficacy screens. (eurekalert.org)
  • To date, there are no open/active SEC petitions from Vitro Manufacturing (Canonsburg). (cdc.gov)
  • Further in vitro and in vivo studies could demonstrate its suitability as an alternative to HRT. (nih.gov)
  • Although the in vivo research is still limited, the weight of evidence from the in vitro and in vivo studies strongly indicate that fluoride is a mutagen, a finding that has significant implications with respect to fluoride's capacity to induce or promote cancer. (fluoridealert.org)
  • However, the extrapolation from in vitro to in vivo requires some careful consideration and is an active research area. (wikipedia.org)
  • I have not tried in-vivo transformation yet, but considering my in-vitro results I would expect the same results. (bio.net)
  • Efficient generation of human induced pluripotent stem cell (hiPSC)-derived human intestinal organoids (HIOs) would facilitate the development of in vitro models for a variety of diseases that affect the gastrointestinal tract, such as inflammatory bowel disease or cystic fibrosis. (genengnews.com)
  • In contrast, we now report the establishment of a robust highly efficient in vitro infection system based on Huh-7-derived cell lines and the JFH-1 consensus clone. (pnas.org)
  • Her team develops strategy and products focused on the modulation of in vitro cell behavior using extracellular matrix, media, vessel design, and growth factors. (corning.com)
  • We want to study the role of microtubules (MTs) in the establishment of cell polarity by reconstitution of an in vitro membrane system that can be polarized with the help of a dynamic MT cytoskeleton. (tudelft.nl)
  • Liver cell models in in vitro toxicology. (nih.gov)
  • In vitro liver cell models also have various applications in toxicology: screening of cytotoxic and genotoxic compounds, evaluation of chemoprotective agents, and determination of characteristic liver lesions and associated biochemical mechanisms induced by toxic compounds. (nih.gov)
  • Transfection of mutated genes into a normal parent cell prior to formation of iPS cells has also been used to make an in vitro disease model. (hindawi.com)
  • A previous report showed that immature cardiomyocytes were obtained in vitro differentiation [ 16 ], suggesting the limitations of using adult stem cells as a cell source for in vitro disease model. (hindawi.com)
  • Taken together, ES cells/iPS cells provide a better cell source of cardiomyocytes required for in vitro disease models. (hindawi.com)
  • Cell senescence in vitro refers to the multitude of physiological, structural, biochemical and molecular changes that occur progressively during serial subcultivation of normal diploid cells, culminating in the permanent cessation of cell division. (els.net)
  • The Hayflick limit can be observed both in vitro and in vivo , and is both cell type‐specific and species‐specific. (els.net)
  • Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. (els.net)
  • Mizuuchi, Kiyoshi, "In Vitro Transposition of Bacteriophage Mu: A Biochemical Approach to a Novel Replication Reaction," Cell, 35:785-794 (1983). (freepatentsonline.com)
  • TN10 Transposition and Circle Formation In Vitro," Cell, 51:101-111 (1987). (freepatentsonline.com)
  • Prior research experience of relevant in vitro experimental techniques/approaches including cell culture of relevant primary cells (fibroblasts, immune cells. (simplyhired.com)
  • This Request for Applications (RFA), Papillomavirus In Vitro Cell Culture Systems, is related to the priority area of sexually transmitted diseases. (nih.gov)
  • ELIGIBILITY REQUIREMENTS Applications may be submitted by domestic and foreign for-profit or nonprofit organizations, public and private, such as universities, medical colleges, hospitals, laboratories, units of State and local governments, and eligible agencies of the Federal government having adequate resources or access to resources to support papillomavirus in vitro cell culture research. (nih.gov)
  • Vitro is the largest glass producer in Mexico and one of the world's largest organizations in the glass industry. (wikipedia.org)
  • The Vitra Campus with buildings by some of the world's leading architects and the Vitra Design Museum with its exhibitions on design and architecture, design archives and a comprehensive furniture collection are all part of Vitra. (londondesignfestival.com)
  • The hamburger looked like any hamburger you might order at a fast food drive-through, but a value menu burger this was not-when the experiment was all said and done, the world's first in vitro sandwich ended up costing more than $300,000. (wired.com)
  • Furthermore, in vivo interaction between endothelial cells and other cells types (such as fibroblasts, pericytes and macrophages) is cumbersome to translate and simulate in vitro . (news-medical.net)
  • In this investigation, we studied the effect of engineered human breast cancer cells on their ability to induce migration of human endothelial cells in an in vitro model. (aiche.org)
  • Interaction between Borrelia burgdorferi and endothelium in vitro. (jci.org)
  • The European Union (EU) pesticides Regulation established that in vitro comparative metabolism studies shall be performed. (europa.eu)
  • The European Food Safety Authority (EFSA) Workshop on in vitro comparative metabolism studies in regulatory pesticide risk assessment discussed the use of these studies to identify human metabolites and to support the assessment of human relevance of chemical‐mediated thyroid disruption. (europa.eu)
  • Zhang's 49-year-old new mom first came to New Hope in January 2007 at age 46, after failing to get pregnant in three inseminations and two in-vitro tries with heavy fertility drugs at another clinic. (nypost.com)
  • The report also divides the global In Vitro Diagnostics (IVD) market into quantitative segments and studies the opportunities available in the regional markets based on geography. (mynewsdesk.com)
  • NEB offers five in vitro RNA synthesis kits, all of which have been optimized to generate reproducible yields of quality RNA. (neb.com)
  • Using human induced pluripotent stem cells, their approach combined a variety of techniques that enabled the development of three-dimensional groups of intestinal cells (organoids) in vitro, which can expand disease treatment testing in the lab using human cells. (genengnews.com)
  • This allowed the researchers to follow the process of how intestinal cells differentiate in vitro. (genengnews.com)
  • If this were the case, then human colonic cancer cells in long-term propagation in vitro should not synthesize this material. (nature.com)
  • The recent development of HCV replicon systems has also permitted the study of HCV translation and RNA replication in human hepatoma-derived Huh-7 cells in vitro ( 13 , 14 ), revealing some of the host-virus interactions that regulate these processes ( 15 - 19 ). (pnas.org)
  • This group also recently reported that Huh-7 cells transfected with in vitro transcribed JFH-1 genomic RNA can secrete infectious viral particles. (pnas.org)
  • Furthermore, the use of in vitro synthesized RNA has been instrumental in the development of RNA vaccines and CRISPR/Cas9 genome editing tools, generation of pluripotent stem cells, as well as development of RNA amplification-based diagnostics. (neb.com)
  • Here we show that low U1 AMO doses increase cancer cells' migration and invasion in vitro by up to 500%, whereas U1 over-expression has the opposite effect. (nature.com)
  • Our results suggest that engineered cancer cells be effective in vascularization of tissue constructs in vitro and can be used in regenerative medicine application. (aiche.org)
  • The relevance of the in vitro findings are further amplified by the fact that there are certain "microenvironments" in the body, such as the bones, oral cavity, kidney, bladder, and pineal gland, where the cells can be exposed to fluoride levels orders of magnitude greater than the fluoride levels found in the blood. (fluoridealert.org)
  • One in vitro study, for example, found that 10 to 19 ppm fluoride caused mutagenic effects in bone cells after 24 to 48 hours of exposure. (fluoridealert.org)
  • In summary, sodium fluoride is mutagenic in cultured mammalian cells and produces transformation of Syrian hamster cells in vitro. (fluoridealert.org)
  • With an increasing global demand for blood units for transfusion, there is much interest in manufacturing red blood cells in vitro. (findaphd.com)
  • SMi's In-Vitro Diagnostics (IVD) will prepare you for the challenging times ahead and how to comply with regulatory requirements to ensure direct access to market ensuring the continued growing demand for use and innovation of IVDs over the next decade and beyond. (smi-online.co.uk)
  • NEW YORK , Nov. 9, 2015 /PRNewswire/ -- This study focuses on China's In Vitro Diagnostics industry assessments and company profiles. (prnewswire.com)
  • But if in vitro meat becomes viable, the environmental and ethical consequences could be profound. (nytimes.com)
  • I predict that the animal welfare movement will expand dramatically in the next several decades as in-vitro meat becomes widely available. (marginalrevolution.com)
  • Encapsulation of proteins into these droplets, like tubulin, MT end-binding protein EB3 and proteins that interact with EB3, provides the opportunity to study in vitro the MT dynamics and the delivery of proteins to the membrane by MTs. (tudelft.nl)
  • In vitro liver preparations are increasingly used for the study of hepatotoxicity of chemicals. (nih.gov)
  • In vitro study. (ingentaconnect.com)
  • These cardiomyocytes worked as in vitro heart disease models since they possessed similar characters to patients' cardiomyocytes. (hindawi.com)
  • Recent microfabrication techniques, such as hydrogel modeling has facilitated the development of vascular network models in vitro. (aiche.org)
  • These in vitro findings strongly suggest that rab5 is involved in the process of early endosome fusion. (nih.gov)
  • the application of genomics , transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. (elsevier.com)
  • A system for in vitro transposition includes a donor DNA that includes a transposable element flanked by a pair of bacterial transposon Tn5 outside end repeat sequences, a target DNA into which the transposable element can transpose, and a modified Tn5 transposase having higher binding avidity to the outside end repeat sequences and being less likely to assume an inactive multimer form than wild type Tn5 transposase. (freepatentsonline.com)
  • Dilute this 1 mM stock solution 1:4 in fresh DMSO to yield a 250 µM stock for labeling proteins in vitro. (neb.com)
  • Thermostable, fast-folding esterase 2 from Alicyclobacillus acidocaldarius serves as a reporter enzyme to monitor in vivo or in vitro expression of eukaryotic and procaryotic proteins. (innovations-report.com)
  • As is typical for in vitro studies, the concentrations of fluoride that have generally been tested are far higher (millimolar levels) than the concentrations found in human blood (micromolar levels). (fluoridealert.org)
  • Giemsa‐stained light microscopic phase‐contrast pictures of serially passaged human skin fibroblasts at various points in their in vitro lifespan. (els.net)
  • Broadly speaking, there are two different types of in vitro studies depending on the type system developed to perform the experiment. (wikipedia.org)
  • In the early 1970s, in vitro studies to determine the potential of a chemical or a mixture to induce point mutations in engineered strains of bacteria indicated that the mutagenic potency of a chemical was a reasonable predictor of its carcinogenic potential. (encyclopedia.com)
  • in vitro Literally 'in glass', but applied more generally to studies on living material that are performed outside the living organism from which the material is derived. (encyclopedia.com)
  • For the estimation of the future lucrativeness of the global market for In Vitro Diagnostics (IVD), the report studies various factors that are expected to positively influence the growth rate. (mynewsdesk.com)
  • Assist with the execution of clinical trials and biomedical studies leading to clinical trial design, including in vivo and in vitro experiments to fulfill. (simplyhired.com)
  • We're still decades away from in vitro meat being anywhere close to a consumer product. (wired.com)
  • This collective, along with van Mensvoort's students at Eindhoven University, have created the In Vitro Meat Cookbook , a collection of more than 50 recipes that explore what the future of meat might be like in the coming decades. (wired.com)
  • In vitro toxicology screening services to address the most complex challenges in early-stage discovery to help inform development strategies, improve safety margins and reduce attrition rates. (intertek.com)
  • The In Vitro Diagnostics Devices market analysis is provided for the Japan markets including development trends, competitive landscape analysis, and key regions development status. (mynewsdesk.com)
  • The In Vitro Diagnostics Devices industry development trends and marketing channels are analyzed. (mynewsdesk.com)
  • Four university laboratories from four European countries and two pharmaceutical companies from Europe have established an efficient research network by combining their multidisciplinary expertises, necessary in the development of an in vitro test battery for efficient screening of oculotoxicity. (europa.eu)
  • However, in light of the current lack of adequate post-market surveillance in many settings, the principles of this guidance may also be applied to other IVDs (either analyte or format) that fall outside the scope of the WHO Prequalification of In Vitro Diagnostics Programme. (who.int)