Vitamin d assay. Medical search. Frequent questions

Recent studies show that globally, over one billion people are vitamin D-deficient 2 , and deficiency rates have increased as people have limited their sun exposure due to the risk of skin cancer. (siemens-healthineers.com)
Vitamin D deficiency has long been associated with rickets in children and osteomalacia in adults, and long-term insufficiency of calcium and vitamin D leads to osteoporosis. (siemens-healthineers.com)
However, in recent years, vitamin D has become an assay of general health status, and there have been multiple publications linking vitamin D deficiency to several disease states, such as cancer, cardiovascular, diabetes, and autoimmune diseases 3 . (siemens-healthineers.com)
Vitamin D deficiency. (siemens-healthineers.com)
The clinical review of vitamin B12 deficiency by Hunt et al was concise and informative. (bmj.com)
However, it did not mention autonomic dysfunction caused by vitamin B12 deficiency. (bmj.com)
The exact mechanism of excessive sweating in vitamin-B12 deficiency is a matter of speculation and will require further studies. (bmj.com)
As the authors state, using serum cobalamin assay to diagnosis vitamin B12 deficiency has its limitations. (bmj.com)
Functional" vitamin B12 deficiency is a syndrome where a wide variety of symptoms in the presence of "normal" serum levels of the vitamin respond to vitamin B12 therapy. (bmj.com)
Autonomic dysfunction, it seems, is a common manifestation of functional vitamin B12 deficiency and seems to occur early in the course of disease process. (bmj.com)
Similarly, in an open study of vitamin B12 deficiency related to food-cobalamin malabsorption in 10 patients, oral crystalline cobalamin was prescribed at a dose of 650mcg per day for at least 3 months. (bmj.com)
To review the evidence about screening for vitamin D deficiency in adults. (uspreventiveservicestaskforce.org)
No studies evaluated the direct benefits or harms of screening for vitamin D deficiency. (uspreventiveservicestaskforce.org)
1-3 Vitamin D deficiency refers to serum levels of vitamin D (serum total hydroxyvitamin D, or 25[OH]D) that are inadequate to support bodily needs. (uspreventiveservicestaskforce.org)
describe the potential health consequences of vitamin D deficiency or excess. (vitamindwiki.com)
What do the data in the published literature show with regard to association of vitamin D deficiency with disease? (vitamindwiki.com)
The last decade has seen a substantial increase in clinical interest in vitamin D deficiency and of laboratory testing for vitamin D status. (vitamindwiki.com)
She is additionally concerned about vitamin D deficiency, having heard this topic discussed on a daytime television talk show. (vitamindwiki.com)
The deficiency of this vitamin in women can cause infantile beriberi, which this article will not specifically address. (nih.gov)
Furthermore, describing how vitamin D levels fluctuate month-to-month may provide a basis for implementing public health strategies to increase 25(OH)D levels when deficiency is most acute. (cdc.gov)
Vitamin D Deficiency: How Much Vitamin D Is Enough? (medicinenet.com)
The biologically active form of vitamin D is 1,25-dihydroxyvitamin D (1,25(OH) 2 D). Measuring serum levels of 1,25(OH) 2 D should be considered upon suspicion of deficiency or excess of 1,25(OH) 2 D. (medscape.com)
Decreased levels of 1,25(OH) 2 D can result from chronic kidney disease , various heritable disorders, tumor-induced osteomalacia, the use of HIV protease inhibitors, or severe vitamin D deficiency . (medscape.com)
Severe vitamin D deficiency: 25(OH)D is the main substrate of 1,25(OH) 2 D. Vitamin D deficiency can affect the production of 1,25(OH) 2 D owing to the lack of substrate. (medscape.com)
Treatment with 25(OH)D can normalize 1,25(OH) 2 D concentrations in patients with vitamin D deficiency. (medscape.com)
In this 20-week, randomized, double-blinded, placebo-controlled trial, 448 Chinese with vitamin D deficiency received 2000 IU/d vitamin D 3 or placebo. (medscape.com)
Supplemented 2000 IU/d vitamin D 3 raised 25(OH)D and 25(OH)D Bio but was unable to correct deficiency in 25% of Chinese participants, which might be partially attributed to the effect of genetic modification. (medscape.com)
Vitamin D deficiency is very common and prescriptions of both assay and supplementation are increasing more and more. (bvsalud.org)

A randomised trial of vitamin D supplementation after CRC surgery has compelling rationale. (bmj.com)
Similarly, Vitamin C supplementation had mixed effects, increasing nAChR responses while providing protection from cell damage in the caudate, the brain region most susceptible to oxidative stress. (nature.com)
The impact of vitamin A supplementation on childhood diarrhea may be determined by the regulatory effect supplementation has on the mucosal immune response in the gut. (nih.gov)
Previous studies have not addressed the impact of vitamin A supplementation on the production of monocyte chemoattractant protein 1 (MCP-1), an essential chemokine involved in pathogen-specific mucosal immune response. (nih.gov)
or =12 mo, 45,000 iu) every 2 mo or a placebo as part of a larger vitamin A supplementation trial. (nih.gov)
If vitamin D screening is warranted, clinicians should use appropriate assays to calculate vitamin D binding protein and bioavailable vitamin D levels concentrations than serum 25(OH)D. In turn, prophylactic vitamin D supplementation to 'correct' insufficient athletes should not be based on serum 25(OH)D measures. (ljmu.ac.uk)
Assessment of OGG1 mRNA levels by RT-PCR did not indicate increased expression of this DNA repair gene after 4 wk of vitamin supplementation. (nih.gov)
This study suggests that long-term vitamin C supplementation at high dose, i. e. 500 mg together with vitamin E in moderate dose, 182 mg, decreases the steady-state level of oxidative DNA damage in mononuclear blood cells of smokers. (nih.gov)
Little is known about how genetic and nongenetic factors modify responses of vitamin D supplementation in nonwhite populations. (medscape.com)
To investigate factors modifying 25-hydroxyvitaminD[25(OH)D] and bioavailable 25(OH)D [25(OH)D Bio ] responses after vitamin D 3 supplementation. (medscape.com)

Vitamin C was analysed at each time point by HPLC, whereas H 2 O 2 -induced MNBC DNA damage was evaluated at 0, 3 and 24 h by means of the comet assay. (cambridge.org)
To investigate the antioxidant effect of vitamin C in terms of oxidative DNA damage measured by the comet assay and DNA repair measured by expression of OGG1 mRNA in blood cells of male smokers given 2 x 250 mg vitamin C daily as plain or slow release tablets combined with plain release vitamin E 2 x 91 mg, or placebo for 4 wk. (nih.gov)
Ingestion of slow release vitamin C formulation was associated with fewer endonuclease III and formamidopyrimidine DNA glycosylase sensitive sites measured by the comet assay in mononuclear blood cells obtained 4 h and 8 h after a single tablet and 4 wk after two tablets a day. (nih.gov)

Measurement of total vitamin D can aid in the correct interpretation of patients' overall health status. (siemens-healthineers.com)
A rapid immunofluorescence assay designed for the point-of-care measurement of serum VitD3 solely was tested. (bvsalud.org)
Twenty-eight laboratories participated in this study and provided 34 sets of results for the measurement of 25(OH)D using 20 ligand binding assays and 14 liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. (psu.edu)
Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique. (who.int)

These findings suggest that vitamin A has an anti-inflammatory effect in the gastrointestinal tract by reducing MCP-1 concentrations. (nih.gov)
Why don't serum vitamin D concentrations associate with BMD by DXA? (ljmu.ac.uk)
Mean serum vitamin D binding protein concentrations were not associated with 25(OH)D concentrations (p=0.392). (ljmu.ac.uk)
Background: Reduced plasma vitamin C (vitC) concentrations in HIV may result from abnormal urinary excretion: a renal leak. (researchgate.net)
Background: Diabetes is associated with low plasma vitamin C concentrations. (researchgate.net)
If 25-hydroxyvitamin D2 and D3 serum concentrations are separately measured and reported as compared with receiving only a total 25-hydroxyvitamin D concentration, how do the additional fractionated data for vitamin D2 and D3 aid clinical interpretation? (vitamindwiki.com)
The most common laboratory test to assess vitamin D nutritional status is total 25-hydroxyvitamin D serum concentrations. (vitamindwiki.com)
Laboratory professionals are often confronted with challenges related to vitamin D testing, including controversy over optimal and target vitamin D concentrations, variable reference ranges across marketed assays and reference laboratories, lack of standardization of vitamin D assays, and misordering of 1,25-dihydroxyvitamin D testing. (vitamindwiki.com)
Higher serum concentrations of folate and vitamin B12 are significantly less likely to be infected with carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs). (greenmedinfo.com)
METHODS: The associations between serum concentrations of folate and vitamin B12 and HR-HPV infections were evaluated in 724 women who participated in a CC screening study in the southern state of Andhra Pradesh, India. (greenmedinfo.com)
Serum folate and vitamin B12 concentrations were measured by using a competitive radio-binding assay. (greenmedinfo.com)
Unconditional logistic regression models specified a binary indicator of HC2 (positive/negative) as the dependent variable and serum folate concentrations combined with serum vitamin B12 concentrations as the independent predictor of primary interest. (greenmedinfo.com)
Vitamin B12 supplement users had significantly higher serum vitamin B12 concentrations. (cdc.gov)

The VITAL-EQA program provides laboratories engaged in public health work an independent, biannual assessment of their analytical performance for serum vitamin A and other selected nutritional biomarkers. (cdc.gov)
The table below lists the various biomarkers for measuring vitamin B12 intake and status. (kcl.ac.uk)
This is a timely concept for biomarkers in the vitamin D pathway as methodology has changed and new biomarkers are emerging. (aacc.org)
Quantifying the amount of within-person short-term variability inherent in those analytes provides insight into the optimal use of vitamin D biomarkers in both research and clinical settings. (aacc.org)
And why is this relevant to laboratory measurements of these biomarkers, like vitamin D for example, that are used in research studies or clinical care? (aacc.org)
García-Bailo B, Da Costa LA, Arora P, Karmali M, El-Sohemy A, Badawi A. Plasma Vitamin D and Biomarkers of Cardiometabolic Disease Risk in Adult Canadians, 2007-2009. (cdc.gov)
The objectives of this study were to examine the association between vitamin D and traditional and novel biomarkers of cardiometabolic disease and to describe the extent of the month-to-month fluctuations of vitamin D in the Canadian population. (cdc.gov)
OBJECTIVES: Folate and vitamin B12 are important biomarkers of nutritional status of populations. (cdc.gov)

The aim of the present investigation was to study the effect of the intake of a single portion of blood orange juice (BOJ, 300 ml, providing 150 mg vitamin C) on mononuclear blood cell (MNBC) DNA damage, compared with a drink supplemented with the same amount of vitamin C (C-drink) or sugars (S-drink). (cambridge.org)

define the indications for assessing 1,25-dihydroxyvitamin D (most biologically active form of vitamin D). (vitamindwiki.com)

Plasma vitamin C concentration increased similarly following BOJ or C-drink intake and was not affected by the S-drink. (cambridge.org)
Objective We assessed the effect of surgical resection of colorectal cancer (CRC) on perioperative plasma vitamin D (25OHD) and C-reactive protein (CRP) level. (bmj.com)
Plasma vitamin E was unaltered in the first 12 h after ingestion of a single tablet, suggesting that the antioxidant effect was mediated by vitamin C. Differences in plasma vitamin C levels at steady state could not explain the difference between the two vitamin C formulations, whereas wider amplitudes of plasma vitamin C were seen after ingestion of plain release formulation compared to slow release formulation. (nih.gov)
Serum or plasma vitamin B12 has been measured using commercially available competitive protein binding immunoassays (CPBA). (kcl.ac.uk)

This assay enables laboratories to provide highly accurate total 25(OH) vitamin D results (~100% D 2 and D 3 ) with a fast turnaround time. (siemens-healthineers.com)
How are 25-hydroxyvitamin D reference ranges (or target values) established, and how do they vary across marketed assays and reference laboratories? (vitamindwiki.com)
Many clinical laboratories in the United States have seen requests for vitamin D testing increase 100% or more in the last 5 years. (vitamindwiki.com)
Emmanuel Romeu is a research and development manager in the Diagnostics branch of Beckman Coulter, a medical diagnostics company, where he specializes in creating novel diagnostic assays for commercial laboratories. (jmp.com)

METHODS: In 604 male athletes (Arab (n=327), Asian (n=48), Black(n=108), Caucasian (n=53)and Hispanic (n=68)), we measured total 25(OH)D, vitamin D-binding protein and BMD by DXA. (ljmu.ac.uk)
In the last 10 years, two methods have been described to accurately analyse human milk vitamin B12 by modifying existing CPBAs to remove interfering amounts of haptocorrin from the milk sample. (kcl.ac.uk)
Published methods for vitamin B12 assay are available in the following references. (kcl.ac.uk)
Methods: An essential prerequisite was determination of normal vitamin C renal threshold, the plasma concentration at whic. (researchgate.net)
14. Gorstein J, Sullivan KM, Parvanta I, Begin F. Indicators and methods for cross-sectional surveys of vitamin and mineral status of populations. (who.int)

Vitamin D receptor (VDR) gene polymorphism is considered to be an important cause of cancer development. (hindawi.com)

25-OH vitamin D has a half-life of 2-3 weeks vs. 4 hours for 1,25-(OH)2-vitamin D. Therefore, 25-OH vitamin D is the analyte of choice for determination of the vitamin D status. (genetrackus.com)
Test4DTM is a rapid chromatographic immunoassay for the detection of vitamin D levels in human blood at a cut-off concentration of 32ng/mL±6ng.mL (80nmol/L±15nmol/L). This assay is designed for qualitative determination of Vitamin D and may be used in the point of care setting. (aksamedical.com)

The ID-Vit® Vitamin B2 Direct MTP Assay is a microtiter plate test kit based on a microbiological method that measures the vitamin B2 content in serum. (idkna.com)
Alternatively, a microbiological assay using L. delbruekiisubsp. (kcl.ac.uk)

Inter- and intra-assay validation, double testing and result comparison with a standardized laboratory method were performed. (bvsalud.org)
Why does the laboratory assay measure 25-OH vitamin D? (genetrackus.com)
It does not provide assay certification or laboratory accreditation. (cdc.gov)
The 25-hydroxyvitamin D serum concentration was determined at the medical center central clinical laboratory by enzyme immunoassay, and results were 29 ng/mL (72 nmol/L), which is in the "insufficiency" range according to the reference ranges on the package insert for the assay. (vitamindwiki.com)

Serum total 25(OH)D is currently considered the best marker of vitamin D status. (uspreventiveservicestaskforce.org)

The Food and Drug Administration (FDA) approved recombinant activated factor VIII (synthetic vitamin K -dependent protein) for treatment of bleeding in patients with hemophilia A or B who have developed inhibitors against replacement coagulation factors. (medscape.com)

Implications for vitamin D screening. (ljmu.ac.uk)
What are the clinical implications of misordering 1,25-dihydroxyvitamin D in place of 25-hydroxy-vitamin D? (vitamindwiki.com)
These findings may have public health implications when recommending vitamin D for the prevention of cardiometabolic disease and related conditions. (cdc.gov)
More studies are needed to elucidate appropriate vitamin D recommendations for Asians and the potential clinical implications of 25(OH)D Bio . (medscape.com)

4.Vitamin E Powder can effectively increase the nucleic acid metabolism, and promote protein synthesis,and increase the body functions and sexual function. (21food.com)
Over the six-week timeframe of the study, variability was quite low for calcium, albumin, vitamin D binding protein, 25(OH)D, and phosphorus. (aacc.org)
Serum 25(OH)D, vitamin D-binding protein (VDBP), parathyroid hormone (PTH) and calcium were measured, and 25(OH)D Bio was calculated based on VDBP levels. (medscape.com)
Vitamin D-binding protein (VDBP), encoded by the GC gene, binds to 85% to 90% circulating 25(OH)D and thereby regulates the vitamin D bioavailability. (medscape.com)

Among asymptomatic, community-dwelling populations with low vitamin D levels, the evidence suggests that treatment with vitamin D has no effect on mortality or the incidence of fractures, falls, depression, diabetes, cardiovascular disease, cancer, or adverse events. (uspreventiveservicestaskforce.org)
Inadequate vitamin D status has been associated with elevated cardiometabolic disease risk, although results are inconsistent, as evidenced by recent meta-analyses pooling multiple study populations (6-8). (cdc.gov)
[ 5 , 6 ] However, the current definition for vitamin D status and related recommendations are mainly based on evidence from white populations, whereas vitamin D metabolism and related health conditions may vary across different racial groups. (medscape.com)
[ 13 ] Thus, it is critically important to clarify whether the commonly used definition for vitamin D status and related recommendation are appropriate for nonwhite populations. (medscape.com)
however, it may not be appropriate in populations with high prevalence of vitamin B(12) insufficiency. (cdc.gov)

3. West KP, Gernand AD, Sommer A. Vitamin A in nutritional anemia. (who.int)
What testing is appropriate for assessment of vitamin D nutritional status, and which patients should have vitamin D testing? (vitamindwiki.com)
Vitamin C (ascorbic acid, AA) has been considered as a complementary nutritional treatment for T2DM. (researchsquare.com)
Moreover, we can provide a specific nutritional content of our product with correct fat, including omega-3, muscle, and vitamins balance. (foodnavigator.com)

Guinea pig 25-hydroxy vitamin D3 (25 HVD3) ELISA kit is Available at Gentaur Genprice with the fastest delivery. (joplink.net)
We measured serum antibodies using an in-house semi-quantitative enzyme-linked immunosorbent assay (ELISA). (cdc.gov)

To address the question of whether shipment at ambient conditions is sufficient for reliable performance of various 25(OH)D assays, the equivalence of DEQAS human serum samples shipped under frozen and ambient conditions was assessed. (psu.edu)
As part of a Vitamin D Standardization Program (VDSP) commutability study, two sets of the same nine DEQAS samples were shipped to participants at ambient temperature and frozen on dry ice. (psu.edu)
Equivalence of the assay response for the frozen versus ambient DEQAS samples for each assay was evaluated using multi-level modeling, paired t-tests including a false discovery rate (FDR) approach, and ordinary least squares linear regression analysis of frozen versus ambient results. (psu.edu)

The factor IX assay is a blood test that measures the activity of factor IX. (medlineplus.gov)

This spectrum of disease usually presents in the absence of any changes in red blood cell indices and is easily misdiagnosed since serum levels of vitamin are in the "normal" range. (bmj.com)
Most of the studies of oral vitamin B12 therapy used serum levels of vitamin and its metabolites as the markers of response to therapy. (bmj.com)

No special preparation is needed for Allergy Papdi Enzyme Assay. (practo.com)
Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Allergy Papdi Enzyme Assay. (practo.com)

This novel, innovative, and controlled study indicates that the evaluated rapid point of care VitD assay is reliable, accurate, and suited for clinical practice. (bvsalud.org)
Objectives: We investigated the contribution of dysregulated vitamin C renal physiology, its prevalence, and associated clinical characteristics. (researchgate.net)
In this study, only 16% of patients with clinical response to cobalamin therapy had low serum levels of the vitamin and values were above 300pg/mL in 54% of cases. (bmj.com)
This article presents a common clinical case scenario regarding vitamin D and an up-to-date discussion and review of the literature on vitamin D testing. (vitamindwiki.com)

The amount of vitamin B2 is directly proportional to the turbidity. (idkna.com)
When the amount of vitamin D is 32± 6ng/mL (80 ±15nmole/L) or more, it will prevent the binding of vitamin D present on the test strip to antibody-gold conjugate. (aksamedical.com)
When amount of vitamin D is less than 32±6ng/mL (80±15nmole/L), there will be free antibody-gold conjugate molecule that will bind to vitamin D on the test strip and will show a colored line in test line zone. (aksamedical.com)

Schroder TH, Quay TA, Lamers Y. Methylmalonic acid quantified in dried blood spots provides a precise, valid, and stable measure of functional vitamin B-12 status in healthy women . (kcl.ac.uk)

Some scholars believe that the lack of nutrients such as vitamin D (VD) and folic acid in the diet can lead to the occurrence of cervical cancer [ 5 ]. (hindawi.com)

an alternative biomarker of vitamin B12 status is to make a neurological assessment, including nerve conduction velocity, vibratory sensation, abnormal gait, peripheral neuropathy and MRI which detects loss of white matter in the spinal cord and brain. (kcl.ac.uk)
In order to address potential weaknesses in previously reported studies, this study incorporated a large number of randomly selected subjects, standardized electrophysiologic assessment of nerve function, and multiple complementary measurements of vitamin-B6 status. (cdc.gov)

The assay system utilizes a monoclonal antibody specific for vitamin D. The assay relies on the competition for binding antibody between vitamin D present in blood sample and vitamin D present on the test strip. (aksamedical.com)

This high prevalence of insufficiency may result from a decreased ability to produce vitamin D endogenously during the winter months (10). (cdc.gov)

OBJECTIVES: This study aimed to estimate the serum folate insufficiency threshold corresponding to the RBC folate threshold for NTD prevention and examine how this threshold is modified by vitamin B(12) status. (cdc.gov)

Levels of the necessary nutrient vitamin C (ascorbate) are tightly regulated by intestinal absorption, tissue accumulation, and renal reabsorption and excretion. (researchgate.net)

The intake of fruits rich in vitamin C seems to increase the antioxidant defence of the organism. (cambridge.org)

However, long-term MET use in diabetics is associated with lower serum levels of total vitamin B 12 . (mdpi.com)
Subjects with hyperhomocysteinaemia had significantly elevated total cholesterol, LDL cholesterol, apolipoprotein A and apolipoprotein B and lower vitamin B levels compared with subjects with 12 normohomocysteinaemia. (who.int)
Vitamin A supplemented children infected with enteropathogenic Escherichia coli (EPEC) had reduced MCP-1 levels (odds ratio = 0.38, 95% CI 0.18-0.80) compared with children in the placebo group. (nih.gov)
Among children not infected with Ascaris lumbricoides vitamin A supplemented children had reduced MCP-1 levels (OR = 0.62, 95% CI 0.41-0.94). (nih.gov)
Used to replace essential vitamins that are not obtained in sufficient quantities in the diet or to further supplement levels. (medscape.com)
WICHITA, Kan. , Feb. 26 /PRNewswire/ -- Bio-Communications Research Institute's (BCRI's) recent research study has found that high levels of vitamin C (ascorbate) inhibit the formation of new blood vessel growth to tumors. (prnewswire.com)
This groundbreaking BCRI study has shown that angiogenesis or the proliferation of new blood vessels, in support of tumor growth, is retarded when high levels of vitamin C are present in the blood. (prnewswire.com)
High levels of vitamin C saturation necessary for angiogenesis to occur are obtainable with the intravenous infusion of vitamin C (ascorbate). (prnewswire.com)
And as you may be aware, vitamin D levels vary dramatically by race. (aacc.org)
Treatment was limited to studies enrolling or analyzing participants with low serum vitamin D levels. (uspreventiveservicestaskforce.org)
To check vitamin D status, the physician selected a vitamin D panel that includes 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D serum levels. (vitamindwiki.com)
Increased 1,25(OH) 2 D levels can result from extrarenal 1α-hydroxylation or hereditary vitamin D-resistant rickets. (medscape.com)

However, two B vitamins, niacin and riboflavin, bind with adenine to form the essential cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), respectively. (wikipedia.org)

Background: Rare plants that contain corrinoid compounds mostly comprise cobalamin analogues, which may compete with cobalamin (vitamin B 12 (B 12 )) metabolism. (mdpi.com)
So Dr. Lutsey, this study measured the individual biological variation in several markers related to calcium metabolism including vitamin D. So let's get basic first. (aacc.org)
Vitamin D has a variety of actions on calcium homeostasis, bone metabolism,and other cellular regulatory functions. (uspreventiveservicestaskforce.org)
Six common polymorphisms in vitamin D metabolism genes were genotyped. (medscape.com)

Antioxidants, in particular vitamin C, have been suggested to decrease oxidative DNA damage. (nih.gov)
Hence, antioxidants, such as vitamin C (ascorbic acid, AA) have been proposed as a means to attenuate WAT inflammation and T2DM 6 . (researchsquare.com)

25-OH vitamin D is present in the blood at up to 1000-fold higher concentration compared to the active 1,25-(OH)2-vitamin D (which is generated from 25-OH vitamin D in the kidneys). (genetrackus.com)

Provides excellent sensitivity for more-accurate differential diagnosis of vitamin D insufficiencies and improved patient care. (siemens-healthineers.com)
Although vitamin C (ascorbate) is present in whole blood, accurate measurements in red blood cells (RBCs) are problematic because of assay interferences, limited sensitivity, and sample volume requirements. (researchgate.net)

We hypothesized that vitamin C renal leak may be associated with disease-mediated renal dysregulation, resulting in aberrant vitamin C renal reabsorption and increased urinary loss. (researchgate.net)

Additionally, the study used state-of-the-art assay measurements. (aacc.org)

This study aims to estimate folate and vitamin B12 usual intakes among US adults and examine folate and vitamin B12 biomarker status by intake source. (cdc.gov)

It plays various roles in the body by binding to vitamin D receptors (VDR) [ 8 ]. (hindawi.com)

however, the protective effect of BOJ was not explained by vitamin C alone, thus other phytochemicals could be involved. (cambridge.org)
Overall the slow release tablets of vitamin C formulation had a more pronounced and a sustained protective effect on base damage compared with the plain release tablets. (nih.gov)

The vitamin D present in the blood sample competes with the vitamin D on the test strip for limited number of antibody-gold conjugate. (aksamedical.com)
The factor VII assay is a blood test to measure the activity of factor VII. (medlineplus.gov)
These products contain high amounts of vitamin C and lower amounts of other phytochemicals such as carotenoids (namely β-cryptoxanthin, lutein, zeaxanthin and β-carotene) and polyphenols (hesperidin, naringenin, cyanidin-3-glucoside, mainly in blood oranges). (cambridge.org)
In the study published in the February 2010 issue of Journal of Angiogenesis Researc h, two assays were used to evaluate the effect of high-doses of vitamin C on the inhibition of new blood vessel growth. (prnewswire.com)
One was ex vivo and one in vivo and both illustrated the inhibition characteristics vitamin C has on new tumor blood vessel growth. (prnewswire.com)
The in vivo assay treated with vitamin C indicated 30% less blood vessel growth than untreated tissue. (prnewswire.com)

A rapid point-of-care assay accurately measures vitamin D. (bvsalud.org)

21.0 vs. 40.5 nmol/L). CONCLUSIONS: The estimated serum folate threshold for optimal NTD prevention was similar to previous reports (24.3 vs. 25.6 nmol/L) among participants with sufficient vitamin B(12) status. (cdc.gov)
221 pmol/L, elevated MMA, combined B(12), impaired vitamin B(12) status), and lower in participants with elevated HbA1c. (cdc.gov)

Ingestion of the vitamin formulation with plain release only indicated a damage-reducing effect 4 h after intake of a single tablet, and the effect was more apparent on endonuclease III than formamidopyrimidine DNA glycosylase sites. (nih.gov)

We can only speculate the reasons behind lack of response to oral vitamin B12 and it may be that cobalamin somehow undergoes a transformation in the portal circulation so is made less able to be internalized by the cells and only when cobalamin is able to bypass portal circulation, the cells internalize it. (bmj.com)

The purpose of the present study was to compare the amounts of vitamin A in sweet potato flour with that of carrot flour and dehydrated carrots by using the biological assay method. (unt.edu)

CONCLUSIONS: These results demonstrated that improving folate and vitamin B12 status in Indian women may have a beneficial impact on the prevention of CC. Micronutrient based interventions for control of HR-HPV infections may represent feasible alternatives to vaccine based approaches to HPV disease prevention, which are currently unaffordable for use in resource limited areas in rural India. (greenmedinfo.com)

Multinomial logistic regression models were used to determine whether vitamin A-supplemented children had different categorical values of MCP-1 compared with children in the placebo group. (nih.gov)

Anatomy11

Organisms1

Diseases39

Chemicals and Drugs77

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Psychiatry and Psychology1

Phenomena and Processes37

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture9

Information Science3

Named Groups3

Health Care28

Geographicals2

Deficiency28

Supplementation10

Comet assay3

Measurement4

Concentrations13

Biomarkers8

Mononuclear blood1

Biologically active form of vitamin1

Plasma vitamin4

Laboratories4

METHODS5

Receptor1

Determination2

Microbiological2

Laboratory4

Total 251

Coagulation1

Implications4

Protein4

Populations5

Nutritional4

ELISA2

DEQAS3

Factor IX1

Serum levels of vitamin2

Enzyme2

Clinical4

Amount of vitamin3

Functional1

Folic acid1

Assessment2

Relies1

Prevalence1

Insufficiency1

Absorption1

Antioxidant1

Levels12

Riboflavin1

Metabolism4

Antioxidants2

Concentration1

Sensitivity2

Urinary1

Measurements1

Biomarker1

Receptors1

Protective effect2

Blood6

Accurately1

Participants2

Damage1

Cobalamin1

Amounts of vitamin1

CONCLUSIONS1

Placebo1