• Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. (sciencedaily.com)
  • RD, Hep-2C, and BGM cells injected with an extract similarly processed but from healthy shrimp, showed no cytopathic effects, even after 7 days of culture ( Figures 1A , 1C , and 1 E ). As a positive control, RD cells were injected with Sabin viral extract and showed the characteristic cytopathic effect produced by an enterovirus infection. (cdc.gov)
  • Exposure of the virus to an acidic milieu is essential for membrane fusion, genome penetration, and productive infection. (phys.org)
  • The virus then fuses with the endosome membrane and injects its genetic material (labeled blue) inside the cell-the steps necessary to kick off a cycle of viral infection and replication. (phys.org)
  • The acidic environment allows enzymes in the endosome or on the cell surface-including TMPRSS2, a key enabler of SARS-CoV-2 infection-to cut the spike protein and facilitate membrane fusion, the team found. (phys.org)
  • Unstained neuroblastoma (SK-N-SH) cell monolayer 72 hours postinfection at low multiplicity of infection (MOI) with equine herpesvirus type 1 showing cell rounding and retraction from the substrate leaving gaps in the monolayer. (asm.org)
  • A down-regulation of mRNA expression was observed for the main regulators of p53 protein stability during infection by the complete set of viruses tested, and a significant decrease in p53 mRNA expression was also observed in H5N1 infected cells. (nih.gov)
  • A number of polypeptides synthesized specifically in Trichoplusia ni multiple nucleocapsid nuclear polyhedrosis virus ( T. ni MNPV)-infected Spodoptera frugiperda cells are phosphorylated both early and late in infection. (microbiologyresearch.org)
  • Many cell proteins continue to be phosphorylated throughout infection. (microbiologyresearch.org)
  • Infection of Spodoptera frugiperda cells with Autographa californica nuclear polyhedrosis virus. (microbiologyresearch.org)
  • Autographa californica nuclear polyhedrosis virus phosphoproteins and synthesis of intracellular proteins after virus infection. (microbiologyresearch.org)
  • Elsegeiny established a mouse model that proved that a single application of rituximab could cause P. jiroveci infection in mice and weaken the type II immune response in the lungs, inactivating the role of CD4+ T cells in the protective immune response[ 8 ]. (ijpsonline.com)
  • In 1996, Peter C. Doherty and Rolf M. Zinkernagel won a Nobel choose which cells to target during a viral infection. (animalresearch.info)
  • With further experiments, it became clear that certain viral proteins were 'presented' by infected cells to the T-lymphocytes, to indicate infection. (animalresearch.info)
  • All HIV-infected persons at risk for infection with M. tuberculosis must be carefully evaluated and, if indicated, administered therapy to prevent the progression of latent infection to active TB disease and avoid the complications associated with HIV-related TB. (cdc.gov)
  • Adding to CDC's current recommendations for administering isoniazid preventive therapy to HIV-infected persons with positive tuberculin skin tests and to HIV-infected persons who were exposed to patients with infectious TB, this report also describes in detail the use of new short-course (i.e., 2 months) multidrug regimens (e.g., a rifamycin, such as rifampin or rifabutin, combined with pyrazinamide) to prevent TB in persons with HIV infection. (cdc.gov)
  • Cell lines infected by HTLV-I express levels of TCR beta mRNA similar to PHA stimulated lymphocytes, suggesting that this gene is not transcriptionally activated as a result of infection by HTLV-I. Cloned T cells of known antigen specificity that are infected by HTLV-I in vitro show impairment of immune function, including loss of antigen-specific responsiveness and the acquisition of alloreactivity. (rupress.org)
  • Morphologically, chloroplasts, mitochondria and nuclei appeared to be unaltered by virus infection and virus particles were not detected in these organelles. (unesp.br)
  • Starting with blood samples from hundreds of infants infected with RSV, human rhinovirus, or influenza over half a dozen cold and flu seasons, the Ohio State University College of Medicine's Octavio Ramilo and colleagues from the US and Finland used array-based gene expression profiling to track down a transcriptional signature coinciding with RSV infection. (genomeweb.com)
  • After dividing samples from the 135 cases with acute RSV infection into four different cohorts, they used Illumina arrays to assess expression patterns in the 45 samples from RSV-infected infants in one of the cohorts, designated the training cohort. (genomeweb.com)
  • In a new study, researchers from the International Agency for Research on Cancer (IARC) and partner institutions investigating drivers of Burkitt lymphoma have identified a molecular signature that is common to both Epstein-Barr virus infection and exposure to aflatoxin B1, two known etiological factors for this cancer type. (who.int)
  • The researchers explored genome-wide DNA methylation profiles in samples of endemic Burkitt lymphoma tissue and identified a molecular signature shared by both Epstein-Barr virus infection and aflatoxin B1 exposure that affects the expression of a putative tumour suppressor, TGFBI. (who.int)
  • The study, published Sept. 6 in Cell Reports , describes the effect of Zika virus infection in the eyes of mouse fetuses, newborns and adults. (sciencedaily.com)
  • To determine what effect Zika infection has on the eye, the researchers infected adult mice under the skin -- similar to the way humans are infected by mosquitoes -- and found live virus in the eyes seven days later. (sciencedaily.com)
  • Eye infection raises the possibility that people could acquire Zika infection through contact with tears from infected people. (sciencedaily.com)
  • The researchers found that the tears of infected mice contained Zika's RNA -- the genetic material from the virus -- but not infectious virus when tested 28 days after infection. (sciencedaily.com)
  • Infection with human immunodeficiency virus (HIV) can result in immunosuppression, allowing opportunistic pathogens to cause disease. (medscape.com)
  • [ 1 , 2 , 3 ] These opportunistic infections were a major source of morbidity and mortality in patients with HIV infection before the development of effective antiretroviral therapy (ART) and still occur today, mostly in infected individuals who are not receiving ART. (medscape.com)
  • Patients with HIV infection are at a greater risk for hepatitis B virus (HBV) infection, due to the common route of transmission. (medscape.com)
  • Co-infection can create a predicament for viruses when you consider that they need to compete for the same resource: you. (bigthink.com)
  • This is the first evidence of this occurring from co-infection of distinct respiratory viruses. (bigthink.com)
  • We know about the significant role co-infection can play in a virus's life, such as during influenza antigenic shift or the curious case of hepatitis D virus borrowing bits of the other viruses , such as hepatitis B, to spread. (bigthink.com)
  • Both up- and down-regulation of host cell gene expression can be followed using RNAseq on poly(A)+ mRNAs harvested from the PBMCs of pigs collected at different times post-infection. (ku.dk)
  • These data suggest that immunization with MVA.HIVA is a feasible strategy to enhance potentially protective T-cell responses in individuals with chronic HIV-1 infection. (ox.ac.uk)
  • Each cell line was inoculated at high multiplicity of infection and examined 24h post-infection. (needtoknow.news)
  • No CPE was observed in any of the cell lines except in Vero cells, which grew to greater than 10 to the 7th power at 24 h post-infection. (needtoknow.news)
  • In contrast, HUH 7.0 and 293T showed only modest viral replication, and A549 cells were incompatible with SARS CoV-2 infection. (needtoknow.news)
  • The above image depicts such an infection in mouse embryo cells. (wuga.org)
  • However, the role of exosomes in virus infection process remains unclear and needs to be further investigated. (virosin.org)
  • In this study, we aimed to evaluate the effects of exosomes on rabies virus infection. (virosin.org)
  • Our results showed that rabies virus infection increased the release of exosomes. (virosin.org)
  • Moreover, our results establish a basis for future research into the roles of exosomes in rabies virus infection and as potential targets for developing new antiviral strategies. (virosin.org)
  • Fevrier M, Dorgham K, Rebollo A (2011) CD4 + T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis. (virosin.org)
  • In agreement with its altered receptor specificity, infection of target cells was no longer dependent on CD150 or CD46, but was restricted to cells that had been labelled with Wue-1 mAb. (elsevierpure.com)
  • Importantly, infection with MV-Wue rapidly induced apoptosis in CD138+ malignant plasma cell targets. (elsevierpure.com)
  • Borna disease virus (BDV) is unique because it establishes a persistent infection and replicates in the nucleus. (elsevierpure.com)
  • People with long COVID-19 have symptoms of the virus - fatigue, body aches, chest pain, or shortness of breath - that persist for months after a COVID-19 infection. (houstonseagle.com)
  • Subacute sclerosing panencephalitis is a slowly progressing fatal human disease of the central nervous system which is a delayed sequel of measles virus (MV) infection. (bgu.ac.il)
  • The mechanisms governing the establishment and maintenance of a persistent MV infection in brain cells are still largely unknown. (bgu.ac.il)
  • As shown previously, treatment of the persistently infected cultures with anti-IFN serum converted the persistent state into a productive infection indicated by the appearance of multinucleated giant cells. (bgu.ac.il)
  • A predictive model of varicella-zoster virus infection after autologous peripheral blood progenitory cell transplantation. (nature.com)
  • Atkinson K, Meyers J, Storb R, Prentice RL, Thomas ED . Varicella-zoster virus infection after marrow transplantation for aplastic anemia or leukemia. (nature.com)
  • Infection with varicella-zoster virus after marrow transplantation. (nature.com)
  • Varicella zoster virus infection associated with high-dose chemotherapy and autologous stem-cell rescue. (nature.com)
  • Knowing the miRNA expression profile will help understand the role of miRNAs in modulating the host response to adenovirus infection and possibly improve the diagnosis of adenovirus-infected pneumonia. (hindawi.com)
  • Therefore, to discover the interaction between the virus and its host will help us to find novel treatment and diagnosis for Adv infection. (hindawi.com)
  • In our study, we sought to present the different miRNA profiles between Adv-infected pneumonia children and healthy controls, identify candidate diagnostic biomarkers for pneumonia with Adv infection in children, and examine the role of miRNAs in host defense response in Adv-infected children. (hindawi.com)
  • Background: Alcohol consumption exacerbates the pathogenesis of hepatitis C virus (HCV) infection and worsens disease outcomes. (nebraska.edu)
  • The goal is for harmless TIPs to outnumber flu virus genetic elements so infected cells would generate relatively few infectious viruses and a bumper crop of "dud viruses" with TIP genes, rapidly diluting the harmful viruses and halting the infection, according to DARPA. (rutgers.edu)
  • Chronic hepatitis C virus (HCV) infection has been implicated in the induction and maintenance of B-cell lymphomas. (unipv.it)
  • Specifically, miR-155 enhances antiviral T cell responses including cytokine secretion, cytolytic activity, and homing to the CNS MA242 in response to viral infection. (afl-journal.org)
  • This is an established and reliable method to accurately measure T cell responses following JHMV infection [42, 43]. (afl-journal.org)
  • Cell isolation and flow cytometry Immunophenotyping of immune cells present within brains and spinal cords of JHMV-infected mice at defined times post-infection (p.i.) was accomplished by homogenizing isolated tissue and generating single-cell suspensions for analysis by flow cytometry using previously described procedures [44C46]. (afl-journal.org)
  • When the Zika epidemic spread through the American continent and then later to Africa and Asia in 2015, researchers compared the characteristics of the Zika infection to Dengue, considering both these viruses were transmitted primarily through the same vector, the Aedes aegypti female mosquitoes. (frontiersin.org)
  • Our results confirm a potential role of NK cells and the different subsets in the pathogenesis of chronic HCV infection. (who.int)
  • et 20 témoins en bonne santé ne présentant pas d'infection par le virus de l'hépatite C. Une réduction importante de la fréquence des cellules tueuses naturelles totales dans le groupe des patients porteurs d'une infection chronique a été observée par rapport au groupe des témoins ( P = 0,001) ou au groupe des patients dont l'infection a connu une résolution spontanée ( P = 0,01). (who.int)
  • Hepatitis C virus (HCV) infection has impaired cellular immune response and circulating NK cells, NK subsets (in- the ability to establish chronic infection virus persistence [8]. (who.int)
  • The elimination or persistence (NKRs) and mediate functions of both cells and CD56+NT cells was charac- of the infection depends on a balance T cells and NK cells [13]. (who.int)
  • The standard of care in Human Immunodeficiency Virus (HIV) infection is the use of a triple drug antiretroviral regimen. (who.int)
  • At a multiplicity of infection of 75 particles per cell, cytopathic effects occurred in 75 to 100% of the cells within 48 h. (lu.se)
  • The virus-infected cells were harvested at various times after infection and analyzed for the ability to bind strains of Haemophilus influenzae and Streptococcus pneumoniae. (lu.se)
  • Adenovirus infection did not change the adherence of cells of poorly adhering strains of S. pneumoniae or H. influenzae. (lu.se)
  • The increased attachment may be one mechanism by which viruses precondition the respiratory mucosa for bacterial infection. (lu.se)
  • The manifestations of the disease are thought to result from the host response to the virus as natural killer cells and cytotoxic T cells respond to infection with the production of interferon and additional inflammatory mediators. (medscape.com)
  • As in acquired infection, congenital disease is thought to result from T-cell and B-cell-mediated injury to the fetal host. (medscape.com)
  • RÉSUMÉ Les objectifs de la présente étude étaient de documenter la prévalence et l'incidence de fond de l'infection par le virus de l'hépatite C chez les agents de santé de l'hôpital universitaire Ain Shams du Caire et d'analyser les facteurs de risque de contracter une infection par le virus de l'hépatite C. Une enquête transversale a été menée en 2008 auprès de 1770 agents de santé. (who.int)
  • HHV-3, also known as varicella-zoster virus (VZV), causes the primary infection chickenpox and the secondary reactivation disease herpes zoster. (medscape.com)
  • HHV-4, also known as Epstein-Barr virus (EBV), causes the primary infection infectious mononucleosis , and it is implicated in various diseases, such as African Burkitt lymphoma , other immunoproliferative disorders, and nasopharyngeal carcinoma. (medscape.com)
  • [ 5 , 6 ] In a localized primary infection, the virus penetrates the mucosal epithelium and invades the cells of the basal layer, where the viral DNA inserts into the host DNA. (medscape.com)
  • Clin Infect Dis;67(9): 1427-1433, 2018 10 15. (bvsalud.org)
  • Senior author James M. Cunningham, M.D., of Brigham and Women's Hospital and Harvard Medical School in Boston, and his colleagues discovered two cellular enzymes that the Ebola virus co-opts and uses to cut up one of the virus' surface proteins. (sciencedaily.com)
  • The first part of the video shown here follows a virus engineered to sprout SARS-CoV-2 spike proteins (labeled pink) as it is captured at a cell surface and engulfed by a cellular compartment called an endosome. (phys.org)
  • Certain non-structural proteins and the major basic internal protein are the main phosphoproteins detected in infected cells. (microbiologyresearch.org)
  • A herpesvirus lacking the γ34.5 gene will not be able to replicate in normal cells because it cannot make proteins. (wikipedia.org)
  • The new "chimeric" virus particles had proteins of both viruses on their surface and some even contained genes from the other. (bigthink.com)
  • Follow-up experiments in the same paper showed that these new chimeric viruses were fully functional and could even infect cells that were rendered resistant to influenza, presumably gaining access using the RSV proteins could even get into a broader range of human cells than either virus alone could. (bigthink.com)
  • DARPA says it wants to harness TIPs - tiny virus-like entities with engineered genetic material that encodes defective viral proteins. (rutgers.edu)
  • In a cell infected with both a flu virus and a TIP, the cell makes copies of the TIP genome that compete for viral proteins. (rutgers.edu)
  • We expressed the lymphoma B-cell receptors as soluble immunoglobulin Gs and membrane IgMs, and analyzed their reactivity with HCV proteins and with HCV virions. (unipv.it)
  • Adherence was not affected by pretreatment of the cells with virus particles or viral proteins. (lu.se)
  • Once the provirus is integrated into the host cell DNA, it is transcribed using typical cellular mechanisms to produce viral proteins and genetic material. (msdmanuals.com)
  • These viral proteins also interact with other several cellular factors and lead to revoke normal cell cycle checkpoint stand cell death mechanisms 13 . (bvsalud.org)
  • Lozano-Sepulveda SA, Bryan-Marrugo OL, Cordova-Fletes C, Gutierrez-Ruiz MC, Rivas-Estilla AM. Oxidative stress modulation in hepatitis C virus infected cells. (wjgnet.com)
  • Figure 1 Possible interactions/mechanisms of antioxidant agents with reported anti-hepatitis C virus effect. (wjgnet.com)
  • Figure 2 Cell signaling pathways modulated by increased reactive oxygen species levels in hepatitis C virus infected cells. (wjgnet.com)
  • Prior to the initiation of ART, all patients who test positive for hepatitis B surface antigen (HBsAg) should be tested for hepatitis B virus (HBV) deoxyribonucleic acid (DNA) using a quantitative assay to determine the level of HBV replication. (medscape.com)
  • All patients with HBV/HIV coinfection must be assessed for hepatitis A virus (HAV) immunity and vaccinated if negative. (medscape.com)
  • Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus. (ox.ac.uk)
  • Herein we analyzed the response of human CD8(+) T cells that recognize both a hepatitis C virus peptide (HCV-NS3) and a peptide derived from the influenza neuraminidase protein (Flu-NA). (ox.ac.uk)
  • of various populations of NKR+ T cells whole blood were withdrawn from Natural killer (NK) cells are potent have been reported to be impaired in each participant on ethylenediamine- antiviral cells which eliminate the vi- chronic hepatitis C patients [16,21]. (who.int)
  • Although miRNAs have been examined in Adv type 3-infected human laryngeal epithelial cells and Adv type 2-infected human lung fibroblast cells [ 19 , 20 ], there is no research about small RNA profiling in whole blood of Adv-infected pneumonia children. (hindawi.com)
  • The present study analyzed the effect of adenovirus on bacterial adherence to human respiratory tract epithelial cells. (lu.se)
  • In HHV-1 and HHV-2 oral infections, viral replication within the oral epithelium may cause lysis of epithelial cells, with vesicle formation. (medscape.com)
  • Zika virus is capable of infecting the eye, according to a new study. (sciencedaily.com)
  • The study, in mice, helps explain why some people with Zika virus develop eye disease, and suggests that contact with infected eyes may play a role in spreading the disease. (sciencedaily.com)
  • Researchers have found that Zika virus can live in eyes and have identified genetic material from the virus in tears, according to a study from Washington University School of Medicine in St. Louis. (sciencedaily.com)
  • Our study suggests that the eye could be a reservoir for Zika virus," said Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine and one of the study's senior authors. (sciencedaily.com)
  • We need to consider whether people with Zika have infectious virus in their eyes and how long it actually persists. (sciencedaily.com)
  • Zika virus causes mild disease in most adults but can cause brain damage and death in fetuses. (sciencedaily.com)
  • About a third of all babies infected in utero with Zika show eye disease such as inflammation of the optic nerve, retinal damage or blindness after birth. (sciencedaily.com)
  • Zika researchers are increasingly considering alternative routes of transmission because the virus is spreading more quickly than would be expected by mosquito-borne transmission alone. (sciencedaily.com)
  • The Zika epidemic has been very explosive, more explosive than we can account for by just mosquitoes and the level of Zika virus in human blood. (sciencedaily.com)
  • Meanwhile, the cross-reactivity of CD8+ and CD4+ T cells response to Dengue and Zika viruses provide important clues for further development of potential treatments. (frontiersin.org)
  • Consideration of the genetic identity of both the Dengue and Zika flaviviruses as well as the cross-reactivity of relevant T cells along with the actions of CD4+ cytotoxic cells in these infections are also presented. (frontiersin.org)
  • Together, this information appraises the current understanding of both Zika and Dengue infections, providing insights for future vaccine design approaches against both viruses. (frontiersin.org)
  • Traditionally, research on the replication of shrimp viruses has been based on the use of cultured fish cellular lines ( 6 ). (cdc.gov)
  • Influenza viruses can modulate and hijack several cellular signalling pathways to efficiently support their replication. (nih.gov)
  • Baculovirus replication: protein synthesis in Spodoptera frugiperda cells infected with Trichoplusia ni nuclear polyhedrosis virus. (microbiologyresearch.org)
  • The ICP34.5 deletion is useful for the construction of oncolytic herpes viruses, as cancer cells do not restrict replication as strongly. (wikipedia.org)
  • Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. (ox.ac.uk)
  • This group said the phenomenon could be related to the process of virus transmission or replication in cells. (web.id)
  • Results Compared to WT mice, JHMV-infected mice developed exacerbated disease concomitant with increased morbidity/mortality and an inability to control viral replication within the CNS. (afl-journal.org)
  • Studies sug- terized by flow cytometry using anti between the immune response and the gest that HCV inhibits receptor genes in CD3, CD56 and CD16 monoclonal virus replication rate [5] and play a cru- the activation of NK cells [20], and the antibodies. (who.int)
  • Some viruses have an outer envelope consisting of protein and lipid, surrounding a protein capsid complex with genomic RNA or DNA and sometimes enzymes needed for the first steps of viral replication. (msdmanuals.com)
  • Classification of viruses is principally according to their genome sequence taking into consideration nature and structure of their genome and their method of replication, but not according to the diseases they cause (see International Committee on Taxonomy of Viruses (ICTV), 2021 release ). (msdmanuals.com)
  • Certain single-strand, (+) sense RNA viruses termed retroviruses use a very different method of replication. (msdmanuals.com)
  • The scientists applied broad-spectrum enzyme inhibitors to mammalian cells before exposing them to Ebola virus. (sciencedaily.com)
  • However, because TSV could potentially represent a public health threat, we explored whether this viral agent might be capable of infecting cultured mammalian cells. (cdc.gov)
  • Once this protein is snipped apart, the virus is free to begin multiplying. (sciencedaily.com)
  • Our data reveal that influenza viruses cause an overall down-regulation of the host p53 pathway and highlight this pathway and p53 protein itself as important viral targets in the altering of apoptotic processes and in cell-cycle regulation. (nih.gov)
  • Protein synthesis in cells infected by Autographa californica nuclear polyhedrosis virus (Ac-NPV): the effect of cytosine arabinoside. (microbiologyresearch.org)
  • Properties of the major nucleocapsid protein of Heliothis zea singly enveloped nuclear polyhedrosis virus. (microbiologyresearch.org)
  • Protein kinase activity associated with the extracellular and occluded forms of the baculovirus Autographa californica nuclear polyhedrosis virus. (microbiologyresearch.org)
  • Trichoplusia ni granulosis virus granulin: a phenol-soluble, phosphorylated protein. (microbiologyresearch.org)
  • Chloroplasts were purified by Percoll gradient, and the coat protein and virus-associated RNAs were extracted and analyzed by Western and Northern blots respectively. (unesp.br)
  • if, in addition, the cells are also infected with vaccinia virus that expresses protein lambda 2, particles are formed that also possess the characteristic icosahedrally located projections/spikes that are present on reovirus cores. (duke.edu)
  • If, in either case, the cells are also infected with vaccinia virus that expresses the reovirus RNA polymerase, protein lambda 3, the resultant particles are morphologically identical with those formed in its absence, but also contain protein lambda 3. (duke.edu)
  • EIF-2A is required for translation so by shutting down eIF-2A, the cell prevents the virus from hijacking its own protein-making machinery. (wikipedia.org)
  • A rabies virus G protein enzyme-linked immunosorbent assay and acetylcholinesterase activity assays were performed to verify the centrifugation fractions. (virosin.org)
  • Gastpar R, Gehrmann M, Bausero MA, Asea A, Gross C, Schroeder JA, Multhoff G (2005) Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells. (virosin.org)
  • In this study, a haemagglutinin (H) protein that was receptor-blinded (i.e. did not bind to CD46 and CD150) was genetically re-engineered by fusing it to a single-chain antibody fragment (scFv) derived from the Wue-1 mAb open reading frame (scFv-Wue), resulting in the recombinant retargeted measles virus (MV)-Wue. (elsevierpure.com)
  • In this study, we have investigated whether alpha/beta IFN produced by NS20Y/MS cells activates cellular protein tyrosine kinases which will induce tyrosine phosphorylating activity specific to virus-infected cells. (bgu.ac.il)
  • We present data to show augmented protein tyrosine kinase activity in the persistently infected cells. (bgu.ac.il)
  • We demonstrate that the MV N protein is phosphorylated on tyrosine in addition to serine and threonine in the persistent state but not in NS20Y cells acutely infected with MV. (bgu.ac.il)
  • RNA viruses like influenza are coated by a protein-studded membrane envelope, Fabris noted. (rutgers.edu)
  • Ideally, the TIPs will be introduced into influenza virus populations and compete for protein, so the virus will starve and not be able to reproduce," she said. (rutgers.edu)
  • Primers were designed for canine distemper virus nucleocapsid protein coding region fragment amplification (84 bp). (scielo.br)
  • Scholars@Duke publication: Generation of reovirus core-like particles in cells infected with hybrid vaccinia viruses that express genome segments L1, L2, L3, and S2. (duke.edu)
  • Instead of isolating the virus, the scientists only looked at 37 out of the approximately 30,000 of the base pairs that are claimed to be the genome of the intact virus. (needtoknow.news)
  • First, in the section titled "Whole Genome Sequencing," we find that rather than having isolated the virus and sequencing the genome from end to end, they found 37 base pairs from unpurified samples using PCR probes This means they actually looked at 37 out of the approximately 30,000 of the base pairs that are claimed to be the genome of the intact virus. (needtoknow.news)
  • Putative anti-host factors show extensive gene duplication via a genomic accordion indicating an ongoing evolutionary arms race and highlighting the rapid evolution and genomic plasticity that has led to genome gigantism and the enigma that is giant viruses. (biorxiv.org)
  • Her role will be to provide imaging and quantification methods to study, in cells and eventually animals, which parts of the influenza virus genome have mutated and to what degree. (rutgers.edu)
  • Members of the Advisory Committee also stressed that Member States need to be aware of recent advances in synthetic biology, which now make it possible to synthesize a full-length variola virus genome. (who.int)
  • Even if poxvirus genome synthesis projects were to be undertaken, the creation of a synthetic variola virus is prohibited by existing regulations. (who.int)
  • Positive-sense RNA viruses possess a single-stranded RNA genome that can serve as messenger RNA (mRNA) that can be directly translated to produce an amino acid sequence. (msdmanuals.com)
  • Negative-sense RNA viruses possess a single-stranded negative-sense genome that first must synthesize a complementary positive-sense antigenome, which is then used to make genomic negative-sense RNA. (msdmanuals.com)
  • Retroviruses use reverse transcription to create a double-stranded DNA copy (a provirus) of their RNA genome, which is inserted into the genome of their host cell. (msdmanuals.com)
  • the genome of RNA viruses ranges from 3.5 kilobases (some retroviruses) to 27 kilobases (some reoviruses), and the genome of DNA viruses ranges from 5 kilobases (some parvoviruses) to 280 kilobases (some poxviruses). (msdmanuals.com)
  • This manageable size together with the current advances in nucleotide sequencing technology means that partial and whole virus genome sequencing will become an essential component in epidemiologic investigations of disease outbreaks. (msdmanuals.com)
  • Chahar HS, Bao X, Casola A (2015) Exosomes and their role in the life cycle and pathogenesis of RNA viruses. (virosin.org)
  • Arvin AM . Varicella-zoster virus: pathogenesis, immunity, and clinical management in hematopoietic cell transplant recipients. (nature.com)
  • These highly upregulated microRNAs may have crucial roles in Adv pathogenesis and are potential biomarkers for adenovirus-infected pneumonia. (hindawi.com)
  • Conclusions: We conclude that Ach disrupts IFNα-induced STAT1 phosphorylation by the up-regulation of USP18 to block the innate immunity protection in HCV-infected liver cells, thereby contributing to HCV-alcohol pathogenesis. (nebraska.edu)
  • DENV as a mosquito-borne virus infects human hosts via the skin, however the initial target cells in the skin remain unclear. (nih.gov)
  • The patients came here with fever and also with pain in their joints," says Dr. Susana Lloveras, an infectious disease physician at Hospital Muñiz in Buenos Aires, Argentina, one of several South American countries where the mosquito-borne virus has surged in 2023. (wuga.org)
  • And always from people bringing the mosquito-borne virus with them from other countries. (wuga.org)
  • We recently investigated and compared the cellular gene expression profiles of human lung A549 cells infected by five different subtypes of human and avian influenza viruses (Josset et al. (nih.gov)
  • Therefore, we examined the capacity of SARS-CoV-2 to infect and replicate in several common primate and human cell lines, including human adenocarcinoma cells (A549), human liver cells (HUH 7.0), and human embryonic kidney cells (HEK-293T). (needtoknow.news)
  • Expansion and diversification of virus-specific T cells following immunization of human immunodeficiency virus type 1 (HIV-1)-infected individuals with a recombinant modified vaccinia virus Ankara/HIV-1 Gag vaccine. (ox.ac.uk)
  • In this study, we performed a comprehensive analysis of the changes in virus-specific CD8(+) and CD4(+) T-cell responses occurring after vaccination of 16 HIV-1-infected individuals with a recombinant modified vaccinia virus Ankara-vectored vaccine expressing the consensus HIV-1 clade A Gag p24/p17 sequences and multiple CD8(+) T-cell epitopes during highly active antiretroviral therapy. (ox.ac.uk)
  • The CoLV was observed to be present as scattered particles interspersed with membranous vesicles and ribosomes or as dense masses of virus particles. (unesp.br)
  • These virus particles reacted by immunolabelling with a polyclonal antibody to CoLV. (unesp.br)
  • When mouse L fibroblasts are infected with various combinations of recombinant vaccinia viruses possessing thymidine kinase (TK) genes with inserted reovirus genes that encode core components, particles are formed that closely resemble reovirus cores. (duke.edu)
  • We hypothesized that only a small fraction of cells within the AMBI-1 clone are activated to produce virus particles during cell division while the majority remain latent despite division, ensuring their survival. (frontiersin.org)
  • A typical pathological feature of this disease is the presence of viral ribonucleocapsid structures in the form of inclusion bodies and the absence of infectious virus or budding viral particles. (bgu.ac.il)
  • When electron microscopy was used, there was no evidence that virus particles bound directly to bacteria. (lu.se)
  • abstract = 'African swine fever virus (ASFV) has become a global threat to the pig production industry and has caused enormous economic losses in many countries in recent years. (ku.dk)
  • ABSTRACT Natural kil er (NK) cel s are key players in the immune response to viruses. (who.int)
  • The researchers, whose paper is published online today in Science Express, identified two cellular enzymes Ebola virus must have to reproduce. (sciencedaily.com)
  • When one specific cellular enzyme, cathepsin B, was inhibited, the infectivity of Ebola virus dropped to near zero. (sciencedaily.com)
  • The cytopathic effect in RD cells began with a partial destruction of the cellular layer. (cdc.gov)
  • Next, small cellular groups and some isolated round cells were observed. (cdc.gov)
  • In Hep-2C cells, the cellular monolayer was partially destroyed. (cdc.gov)
  • The cytopathic effect in the BGM cell line began as a partial destruction of the cellular layer, which evolved to a syncytial-like formation of rounded, refringent cells. (cdc.gov)
  • Since CD8(+) and CD4(+) T cells are crucial to HIV-1 control, stimulation of potent cellular responses by therapeutic vaccination might be exploited to reduce antiretroviral drug exposure. (ox.ac.uk)
  • These findings show that the vast majority of HIV-1 proviruses within expanded T cell clones, including intact proviruses, may be transcriptionally silent at any given time, implying that infected T cells may be able to be activated to proliferate without inducing the expression of the integrated provirus or, alternatelively, may be able to proliferate without cellular activation. (frontiersin.org)
  • Adv infects the host cells through binding to different cellular receptors such as coxsackievirus and adenovirus receptor (CAR) [ 12 ]. (hindawi.com)
  • The focus is on discovering how the influenza virus mutates at the cellular, animal and population levels, said Fabris, who works in the School of Engineering . (rutgers.edu)
  • Right now, there's just one virus on everyone's minds: SARS-CoV-2, the virus that causes COVID-19. (bigthink.com)
  • CDC Study Admits COVID 'Virus' Infects Only Poisoned Monkey Cells, Not Humans! (needtoknow.news)
  • SARS-CoV-2 is the name of the virus that is claimed to cause the disease Covid-19. (needtoknow.news)
  • Tixagevimab and cilgavimab injection is currently being studied for the prevention of coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus. (medlineplus.gov)
  • Researchers say a new study may help explain why the COVID-19 virus seems to hit particularly hard those who are obese, leading to a higher risk of severe illness and death. (houstonseagle.com)
  • The applicability of cytoreductive treatment of malignant diseases using recombinant viruses strongly depends on specific recognition of surface receptors to target exclusively neoplastic cells. (elsevierpure.com)
  • In the 1970s, Peter C. Doherty and Rolf M. Zinkernagel studied the immune responses of mice to uncover how T-lymphocytes decide which cells to kill and which to spare. (animalresearch.info)
  • T cells harvested from infected mice were used to examine cytolytic activity, cytokine activity, and expression of certain chemokine receptors. (afl-journal.org)
  • To determine the impact of miR-155 on trafficking, T cells from infected WT or mice were adoptively transferred into mice, and T cell accumulation into the CNS was assessed using flow cytometry. (afl-journal.org)
  • In corroboration with increased susceptibility to disease, mice had diminished CD8+ T cell responses in terms of numbers, cytolytic activity, IFN- secretion, and homing to the CNS that corresponded with reduced expression of the chemokine receptor CXCR3. (afl-journal.org)
  • Both IFN- secretion and trafficking were impaired in JHMV-infected mice, and the severity of demyelination was similar at 14?days p.i. between WT and JHMV-infected mice. (afl-journal.org)
  • 105 PFU) strain [31, 42] was used to immunize experimental mice via i.p. injection to generate virus-specific T cells. (afl-journal.org)
  • CD8+ T cell cytotoxicity assay WT and mice were infected i.p. with the DM strain of JHMV (DM-JHMV, 2.5? (afl-journal.org)
  • Fractionation of cells into nucleus and cytoplasm showed that polypeptides located in both the cytoplasm and nucleus were phosphorylated. (microbiologyresearch.org)
  • An area showing altered staining behavior in the nucleus or cytoplasm of a virus-infected cell. (bvsalud.org)
  • Ebola virus reproduction in laboratory-grown cells is severely hampered by enzyme-inhibiting chemicals, and these chemicals deserve further study as possible treatments for Ebola virus infections in humans, report scientists supported in part by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH). (sciencedaily.com)
  • Even though we didn't find live virus in mouse tears, that doesn't mean that it couldn't be infectious in humans," said Jonathan J. Miner, MD, PhD, an instructor in medicine and the study's lead author. (sciencedaily.com)
  • We are planning studies in people to find out whether infectious virus persists in the cornea or other compartments of the eye, because that would have implications for corneal transplantation," said Rajendra S. Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Science, and the study's other senior author. (sciencedaily.com)
  • Even if human tears do not turn out to be infectious, the researchers' detection of live virus in the eye and viral RNA in tears still has practical benefits. (sciencedaily.com)
  • The occurrence of varicella zoster virus (VZV) reactivation is increased after allogeneic transplantation, whereas limited data are available for herpes zoster (HZ) after autologous SCT (ASCT). (nature.com)
  • Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. (nature.com)
  • Cross-reactivity of murine and recently human CD8(+) T cells between different viral peptides, i.e., heterologous immunity, has been well characterized. (ox.ac.uk)
  • The researchers now are planning complementary studies in human patients infected with the virus. (sciencedaily.com)
  • This new research sheds light on the mechanism Ebola virus uses to enter cells," notes NIAID Director Anthony S. Fauci, M.D. "These findings raise the possibility of a broad-spectrum antiviral therapy that could be effective against multiple hemorrhagic fever viruses. (sciencedaily.com)
  • We obtained lymphoma tissues from HCV-infected lymphoma patients, including some that later regressed upon antiviral treatments. (unipv.it)
  • Microscopic image of the subcuticular tissue of the pleopod from a shrimp infected with the supernatant of the third passage of a human larynx carcinoma (Hep-2C) cell culture inoculated with an. (cdc.gov)
  • Two tissue culture media for production of lepidopteran cell lines and nuclear polyhedrosis viruses. (microbiologyresearch.org)
  • The virologists introduced solutions they say contain the virus into a variety of tissue cultures, including three that contained human cells. (needtoknow.news)
  • The only tissue cultures that did become infected were monkey kidney cells that were treated with two potent drugs that are toxic to kidneys. (needtoknow.news)
  • Researchers found that while fat cells could be infected by the coronavirus, when immune cells in the fat tissue were also involved, a robust inflammatory response was triggered. (houstonseagle.com)
  • The Stanford study's senior authors, Dr. Tracey McLaughlin and Dr. Catherine Blish, found a dramatic inflammatory response happened soon after the fat tissue was infected by the coronavirus. (houstonseagle.com)
  • To understand the mechanisms underlying MV persistence in neuronal cells, a tissue culture model was studied. (bgu.ac.il)
  • To determine the expression of tissue inhibitors of metalloproteinases (TIMP-2) in oral squamous cell carcinoma (OSCC) and the difference in its expression level between positive and negative HPV-16 (human papilloma virus- 16) OSCC patients. (bvsalud.org)
  • The recurrence is a serious prognostic influence in patients with oral squamous cell carcinoma (OSCC) 1-3 . (bvsalud.org)
  • HPV infections have received particular attention in recent years, as high-risk strains have been linked to some cases of oral squamous cell carcinoma. (medscape.com)
  • The signature also distinguished between samples from infants with RSV and those with other types of respiratory tract infections - including those caused by the influenza virus or human rhinovirus - with around 94 percent sensitivity and 98 percent specificity. (genomeweb.com)
  • Beyond the neonatal period, most primary HSV-1 infections occur in infancy and childhood and are transmitted primarily by contact with infected saliva. (medscape.com)
  • Infected saliva or droplets spread the viruses in the oral cavity. (medscape.com)
  • Also, see the Herpes Simplex Viruses: Test Your Knowledge slideshow for more information on clinical, histologic, and radiographic imaging findings in HSV-1 and HSV-2. (medscape.com)
  • Vaccine-driven CD8(+) T-cell expansions were also detected by tetramer reactivity, predominantly in the CD45RA(-) CCR7(+) or CD45RA(-) CCR7(-) compartments, and persisted for at least 1 year. (ox.ac.uk)
  • The FDA approval is for Ixchiq - the first vaccine for the chikungunya virus, for those age 18 and older. (wuga.org)
  • Canine distemper virus vaccine samples in VERO cells were used as positive controls. (scielo.br)
  • 2001 . Genetic characterization and the geographic distribution of rabies virus isolates in Brazil: identification of two reservoirs, dogs and vampire bats . (ajtmh.org)
  • It is passed to humans when they inhale, consume, or otherwise contact infected excreta. (medscape.com)
  • The most notable changes in these guidelines reflect both the findings of clinical trials that evaluated new drug regimens for treating and preventing TB among HIV-infected persons and recent advances in the use of antiretroviral therapy. (cdc.gov)
  • All HIV-infected patients undergoing treatment for TB should be evaluated for antiretroviral therapy, because most patients with HIV-related TB are candidates for concurrent administration of antituberculosis and antiretroviral drug therapies. (cdc.gov)
  • Ideally, the management of TB among HIV-infected patients taking antiretroviral drugs requires a) directly observed therapy, b) availability of experienced and coordinated TB/HIV care givers, and in most situations, c) use of a TB treatment regimen that includes rifabutin instead of rifampin. (cdc.gov)
  • The study , which has not yet been peer-reviewed, showed that the virus can directly infect fat cells and immune cells within body fat. (houstonseagle.com)
  • As the virus destroys and impairs the function of immune cells, infected individuals gradually become immunodeficient. (who.int)
  • Herpes simplex virus (HSV) infections are ubiquitous and have a wide range of clinical manifestations (see the images below). (medscape.com)
  • NEW YORK (GenomeWeb News) - The molecular signatures associated with a child's immune response to respiratory syncytial virus may provide hints to the severity of lower respiratory tract infections the virus causes, according to a new study in PLOS Medicine . (genomeweb.com)
  • Research shows that up to 30% of infections may harbour more than one virus. (bigthink.com)
  • Nevertheless, the work by the University of Glasgow researchers has significant implications for our understanding of how other very different respiratory viruses might interact, antagonise and even promote each other's infections in the ecosystem of our nose and lungs. (bigthink.com)
  • The human immunodeficiency virus (HIV) targets cells in the immune system - the body's defence against illness - and weakens the body's ability to fight against infections and some types of cancer. (who.int)
  • Viruses are thought to facilitate bacterial infections of the respiratory tract, but the mechanisms are poorly understood. (lu.se)
  • Adenovirus (types 1, 2, 3, and 5) commonly causing respiratory tract infections increased the binding of adherent S. pneumoniae strains to the cells. (lu.se)
  • A Cluster of Lymphocytic Choriomeningitis Virus Infections Transmitted Through Organ Transplantation - Iowa, 2013. (medscape.com)
  • Human Advs are nonenveloped double-stranded DNA viruses and belong to the Adenoviridae family [ 7 , 8 ]. (hindawi.com)
  • HPVs are small non-enveloped, double-stranded, circular DNA viruses that encode two viral oncoproteins, E6 and E7. (bvsalud.org)
  • In addition, several p53 target genes were also down-regulated by these influenza viruses and the expression of their product reduced. (nih.gov)
  • This sometimes occurs when two different influenza strains meet up inside the same cell and exchange genes, allowing a new variant to emerge. (bigthink.com)
  • It's important to point out that the researchers in this study did not perform any genetic engineering between two viruses and only modelled what is already happening in the real world, but using safer laboratory strains of viruses under lab conditions. (bigthink.com)
  • Dengue virus (DENV) is the most disease causative flavivirus worldwide. (nih.gov)
  • Dengue virus (DENV) is an enveloped, single-stranded RNA virus belonging to the Flaviviridae family. (frontiersin.org)
  • Alex J. B. Kreutzberger et al, SARS-CoV-2 requires acidic pH to infect cells, Proceedings of the National Academy of Sciences (2022). (phys.org)
  • The virus destroys white blood cells in the immune system called CD4 cells and replicates itself inside these cells. (who.int)
  • Gag-specific CD8(+) and CD4(+) T-cell proliferation also increased postvaccination. (ox.ac.uk)
  • Peripheral blood mononuclear cells (PBMCs) from pigs infected with ASFV not only express ASFV genes (almost 200 in number) but have altered patterns of host gene expression as well. (ku.dk)
  • The patterns of changes in gene expression within the PBMCs detected by RNAseq were similar in each of the four infected pigs. (ku.dk)
  • The researchers' work reveals that viruses can't fuse with the membrane and release their genomes unless they're bathed in a slightly acidic environment. (phys.org)
  • The researchers looked at what happens to each virus using high-resolution imaging techniques, such as cryo-electron microscopy, that their labs have perfected over the years. (bigthink.com)
  • Japanese researchers managed to capture microscopic images of cells infected with the Corona virus using an ultra high-definition camera. (web.id)
  • When that happens, researchers say, the body triggers an immune response that may contribute to a severe case of the virus. (houstonseagle.com)
  • The results were consistent with other studies that have showed that viruses can infect fat cells, the researchers wrote . (houstonseagle.com)
  • The more fat cells a person has, the more of a reservoir for the virus to multiply, and the greater the chance an inflammatory response can trigger problems throughout the body, researchers said. (houstonseagle.com)
  • Configuration and expression of the T cell receptor beta chain gene in human T-lymphotrophic virus I-infected cells. (rupress.org)
  • We studied the configuration and expression of the gene encoding the beta chain of the T cell receptor (TCR beta) in cell lines and primary tumor cells infected by the human T cell leukemia/lymphoma (lymphotrophic) virus type I (HTLV-I). Most of the cell lines and all the primary tumor cells showed rearrangement of the TCR beta gene, and in each case the rearrangement was distinct. (rupress.org)
  • The mechanism by which Ach down-regulates pSTAT1 is related to an enhanced interaction between IFNαR2 and USP18 that finally dysregulates the cross talk between the IFN receptor on the cell surface and STAT1. (nebraska.edu)
  • Other members of Arenaviridae include Lassa, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever viruses. (medscape.com)
  • The University of Glasgow study investigated what happens when you infect cells in a dish with two human respiratory viruses. (bigthink.com)
  • The causal agent is a single-stranded (+) RNA virus, recently reported to be genomically related to the Cricket Paralysis virus of the Cripavirus genus, family Dicistroviridae of the "picornavirus superfamily" ( 2 - 5 ). (cdc.gov)
  • Lymphocytic choriomeningitis virus (LCMV) is a single-stranded RNA virus of the family Arenaviridae. (medscape.com)
  • Increasing numbers of non-human immunodeficiency virus-infected individuals with non-Hodgkin's B cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone have been diagnosed with Pneumocystis pneumonia. (ijpsonline.com)
  • Non-B-Cell Hodgkin's Lymphoma (NHL) is now first line treated with Rituximab plus Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP)[ 1 ]. (ijpsonline.com)
  • PCP is commonly reported in non-Human Immunodeficiency Virus (HIV) positive lymphoma patients receiving R-CHOP, and it is thought that rituximab is responsible for its incidence in these individuals[ 2 , 3 ]. (ijpsonline.com)
  • These guidelines update previous CDC recommendations for the diagnosis, treatment, and prevention of tuberculosis (TB) among adults and children coinfected with human immunodeficiency virus (HIV) in the United States. (cdc.gov)
  • Early diagnosis and effective treatment of TB among HIV-infected patients are critical for curing TB, minimizing the negative effects of TB on the course of HIV, and interrupting the transmission of Mycobacterium tuberculosis to other persons in the community. (cdc.gov)
  • This technique could detect even a few copies of viral RNA and identificate subclinically infected dogs providing accurate diagnosis of this disease at an early stage. (scielo.br)
  • Congenital Lymphocytic Choriomeningitis Virus: When to Consider the Diagnosis. (medscape.com)
  • Fusion activity depends on two proteolytic cleavage steps, namely, one typically carried out by furin in the producing cell and the second by TMPRSS2 on the cell surface on in endosomes of the target cell. (phys.org)
  • It is not yet known whether the virus typically makes that trip by crossing the blood-retina barrier that separates the eye from the bloodstream, traveling along the optic nerve that connects the brain and the eye, or some other route. (sciencedaily.com)
  • Immune function is typically measured by CD4 cell count. (who.int)
  • Viruses are among the smallest microbes, typically ranging from 0.02 to 0.3 micrometer, although several very large viruses up to 1 micrometer in length (megavirus, pandoravirus) have recently been discovered. (msdmanuals.com)
  • When those enzymes are blocked, the virus loses most of its infectivity, the scientists found. (sciencedaily.com)
  • In a first, scientists have captured on video all the steps a virus follows as it enters and infects a living cell in real time and in three dimensions. (phys.org)
  • The purpose of the article was for a group of about 20 virologists to describe the state of the science of the isolation, purification and biological characteristics of the new SARS-CoV-2 virus, and to share this information with other scientists for their own research. (needtoknow.news)
  • Scientists in Italy and Texas now have discovered a new way that these cells die - by toxic imbalance of a molecule secreted by other pancreatic cells. (medicaldaily.com)
  • For the first time in virology, Fabris and her team will use imaging tools with gold nanoparticles to monitor mutations in the influenza virus, with unprecedented sensitivity, when it enters cells. (rutgers.edu)
  • Early Juvenile Human T-cell Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis: Study of 25 Patients. (bvsalud.org)
  • A new study looks at what happens when you get infected with two viruses at the same time. (bigthink.com)
  • A recent study from the University of Glasgow has discovered what happens when you get infected with some of these viruses at the same time, and it has implications for how they make us sick and how we protect ourselves from them. (bigthink.com)
  • Dr. Tom Cowan published an astonishing analysis of a study from the CDC that admits that the SARS-CoV-2 "virus" has not been properly isolated or purified, which means that they cannot prove that a novel, never-been-seen-before virus, even exists. (needtoknow.news)
  • In our study, total RNA extracted from whole blood of adenovirus-infected pneumonia children and healthy controls were analyzed by small RNA deep sequencing. (hindawi.com)
  • Methods: In this study, we aimed to explore the mechanisms of how alcohol metabolism dysregulates IFNα signaling (STAT1 phosphorylation) in HCV + hepatoma cells. (nebraska.edu)
  • In order to study the possible role over Ficoll-Hypaque (density 1.077 production, and are the key players in that NK cells might play in the patho- g/L) (Amersham Biosciences) and immune responses to viruses [7]. (who.int)
  • One-step growth curve experiments revealed that the phages have latent periods of 50-80 min with burst sizes of 44-65 virions per infected cell. (mdpi.com)
  • Amusingly enough, measuring the pH of the nostril cavity has rarely been done before," noted co-senior author Tomas Kirchhausen, professor of cell biology in the Blavatnik Institute at Harvard Medical School and HMS professor of pediatrics at Boston Children's Hospital. (phys.org)
  • Development of most solid tumors is characterized by an increase in secretion and activation of matrix metalloproteinases (MMPs) produced by either the tumor cells or tumor-associated fibroblasts. (bvsalud.org)
  • Here we demonstrate that TSV also infects human cell lines, which may suggest that Penaeus is a potential reservoir of this virus. (cdc.gov)
  • The fat itself may actually become a reservoir for the virus and somehow be involved in its inflammatory response. (houstonseagle.com)
  • Captured images show the experimental animal cells began to change shape four hours after being injected with the coronavirus. (web.id)
  • In all pairs examined, the configuration in the primary tumor cells was different from that in the cell lines, strongly suggesting that the cells that grow in culture are not the original neoplastic cells. (rupress.org)
  • What happens when two different respiratory viruses infect the same cell? (bigthink.com)
  • But humanity is plagued by many respiratory viruses, such as influenza A (IAV) and respiratory syncytial viruses (RSV), which cause hundreds of thousands of deaths every year . (bigthink.com)
  • For many reasons, respiratory viruses are often found during winter in the temperate regions of the world, or the rainy season of equatorial regions. (bigthink.com)
  • Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? (mdpi.com)
  • Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. (mdpi.com)
  • Respiratory viruses can also exacerbate asthma and lead to various types of respiratory distress syndromes. (mdpi.com)
  • A recently generated monoclonal antibody (mAb), Wue-1, specifically detects CD138 + multiple myeloma (MM) cells. (elsevierpure.com)