Viruses including nipah virus. Medical search. Frequent questions

The P4 lab began formal operations in January 2018, and its work includes research on Ebola and Nipah viruses. (scmp.com)
Other bat associated viruses that have caused panic epidemics include, Ebola, Nipah and Hanta virus. (colombotelegraph.com)
Since it began, RAPIDD has been credited with enhancing the understanding of pathogens ranging from measles, Ebola and rabies to the less well known Nipah virus and the Leptospirosa interrogans bacterium. (nih.gov)
GS-5734 is a monophosphate prodrug of an adenosine nucleoside analog that showed therapeutic efficacy in a non-human primate model of Ebola virus infection. (nature.com)
It has been administered under compassionate use to two Ebola patients, both of whom survived, and is currently in Phase 2 clinical development for treatment of Ebola virus disease. (nature.com)
Viruses belonging to the families Paramyxoviridae, Coronaviridae and Filoviridae include zoonotic and human pathogens that are of significant public health concern, ranging from vaccine-preventable diseases such as Measles (MV) and Mumps (MuV) viruses to highly pathogenic viruses such as Nipah (NiV), Middle East Respiratory Syndrome (MERS) and Ebola (EBOV) viruses, for which there are currently no approved therapeutics for human use. (nature.com)
More importantly, this compound protected non-human primates from lethal Ebola virus infection when given therapeutically beginning 3 days post-inoculation, and is currently in phase 2 clinical development for treatment of Ebola virus disease. (nature.com)
She is also an expert in imaging high-consequence viral infections such as Ebola, Nipah and Lassa viruses, in collaboration with the Integrated Research Facility (NIAID), a BSL-4 biomedical research facility based in Fort Detrick, Maryland. (nih.gov)
How does it relate to influenza, Ebola or hemorrhagic viruses? (ouvry.com)
Of mortality similar to that of the Ebola virus it kills on average 7 patients out of 10. (ouvry.com)

A Nipah virus infection is a viral infection caused by the Nipah virus. (wikipedia.org)
Death occurs in 40-75% of cases, and some long-term side effects of infection include persistent convulsions and personality changes. (wikipedia.org)
After recovery, IgG and IgM antibody detection can confirm a prior Nipah virus infection. (wikipedia.org)
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched an early-stage clinical trial evaluating an investigational vaccine to prevent infection with Nipah virus. (nih.gov)
Nipah virus infection is a zoonotic disease, meaning that it is spread between animals and people. (nih.gov)
The virus can cause mild-to-severe disease rapidly progressing from respiratory infection symptoms to encephalitis (brain swelling) leading to coma or death. (nih.gov)
Currently, there is no licensed vaccine or treatment for Nipah virus infection. (nih.gov)
Experts say that the Nipah virus is not an airborne infection. (smartparenting.com.ph)
Respiratory epithelium appears to be the major site of virus binding and subsequent infection. (medscape.com)
Nipah virus is a bat-borne emerging infection, and Pteropus species bats are the wildlife reservoir. (cdc.gov)
Three clusters were identified, consisting of 14 case-patients (9 with confirmed Nipah virus infection, 5 with probable Nipah virus infection). (cdc.gov)
When Kerala, a state in south India, recently found itself confronting the deadly bat-borne Nipah virus for the fourth time in five years, it had its operation manual at the ready, and managed to contain the infection within just a week. (gavi.org)
According to Anish, it's important that the state's health system is sensitive: capable of detecting clustering of encephalitis or acute respiratory distress syndrome, two typical symptoms of Nipah infection, even in 'single-case clusters' - meaning outbreaks that involve just a single patient. (gavi.org)
In this photograph taken on September 12, 2023, health workers wearing protective gear shift the body of a person who died of a Nipah virus infection at a private hospital in Kozikode, in India's Kerala state. (dailycaller.com)
Their close contact promotes mutual infection and provides for great variety in circulating viruses. (sciencedaily.com)
This photomicrograph revealed some of the histopathologic changes associated with a Nipah virus infection. (cdc.gov)
Infection with Nipah virus has been associated with an encephalitis characterized by fever and drowsiness, and more serious central nervous system disease, including coma, seizures, and inability to maintain breathing. (cdc.gov)
Zhengli Shi of the Chinese Academy of Sciences in Beijing and colleagues sampled more than 400 bats of various species across China and found up to 70 percent of some species showed evidence of infection with SARS-like viruses. (247wildlife.com)
Bats do not demonstrate an inflammatory response to infection with the typical response of inflammatory mediators including cytokines that often leads to pathological damage to its own tissues. (colombotelegraph.com)
Finally, the authors showed how the changing geometry of flying fox habitat was strongly associated with Hendra virus spillovers, adding knowledge about epidemiology and infection ecology of this rare, but fatal zoonosis. (gbif.org)
The virus that causes Rabies is present around the world (with the exception of Antarctica) and all mammals are susceptible to infection. (iamat.org)
The infection responsible for this disease, Nipah virus, originated in fruit bats. (animalresearch.info)
There is no specific treatment for Nipah virus infection, but supportive care can help to improve the patient's chances of survival. (thecomputech.co.in)
In May 2018, Kerala, India experienced an outbreak of Nipah virus infection. (thecomputech.co.in)
In 2019 and 2021, there were two more deaths due to Nipah virus infection in Kerala. (thecomputech.co.in)
Avoid contact with sick people who may have Nipah virus infection. (thecomputech.co.in)
It would also help to protect people who are at high risk of Nipah virus infection, such as those who live in or near areas where Nipah virus is known to occur, or those who work with bats or other animals that may be infected with Nipah virus. (thecomputech.co.in)
There is a need for a Nipah virus vaccine to prevent and control Nipah virus outbreaks, and to protect people who are at high risk of infection. (thecomputech.co.in)
Other regions may be at risk for infection, as evidence of the virus has been found in the known natural reservoir ( Pteropus bat species) and several other bat species in a number of countries, including Cambodia, Ghana, Indonesia, Madagascar, the Philippines, and Thailand. (blessbpeprah.com)
Initial signs and symptoms of Nipah virus infection are nonspecific, and the diagnosis is often not suspected at the time of presentation. (blessbpeprah.com)
Nipah virus infection can be diagnosed with clinical history during the acute and convalescent phase of the disease. (blessbpeprah.com)
Dr. Hammoud's research interests include the development of preclinical, translational and clinical molecular imaging applications to improve the understanding of the pathophysiology of infection, and to provide reliable pathogen specific imaging biomarkers of infectious diseases. (nih.gov)

The death rate for Nipah ranges from 40% up to 75% , depending on where the outbreak occurs. (bbc.com)
The first known Nipah outbreak occurred in 1998 in Malaysia and Singapore and resulted in 265 human cases and 105 deaths, and caused significant economic damage to the swine industry there. (nih.gov)
Kerala , a state in southern India is currently dealing with an outbreak of the Nipah virus . (smartparenting.com.ph)
September's outbreak saw the state press its experience of the virus into service. (gavi.org)
Two people have died in India of the Nipah virus as of Friday, according to multiple reports, forcing authorities to ramp up efforts to mitigate a larger outbreak. (dailycaller.com)
This is the fourth outbreak of Nipah since 2018. (dailycaller.com)
GODOY: Well, we've got an outbreak of the Nipah virus in Kerala, India. (wrkf.org)
The outbreak was eventually brought under control, but it was a reminder of the serious threat posed by Nipah virus. (thecomputech.co.in)
Nipah virus was first recognized in 1999 during an outbreak among pig farmers in, Malaysia. (blessbpeprah.com)
Nipah virus was first identified in 1999 during an outbreak of encephalitis and respiratory diseases among pig farmers in Malaysia and Singapore in 1998. (ouvry.com)

The highly dangerous Hendra and Nipah viruses cause types of encephalitis that result in death for one out of two patients. (sciencedaily.com)
The findings also included that the Hendra and Nipah viruses that cause encephalitis in Asia and Australia really came from Africa. (sciencedaily.com)
Bats are hosts of several other new viruses, including Hendra and Nipah viruses, and rarely become ill. (247wildlife.com)
On the map below, we can draw a parallel between the bat's habitat and the infectious cases of Hendra and Nipah viruses. (ouvry.com)

Someone with Nipah virus may experience respiratory symptoms including a cough, sore throat, aches and fatigue, and encephalitis, a swelling of the brain which can cause seizures and death. (bbc.com)
A total of 33 outbreaks of Nipah virus encephalitis were reported in Bangladesh and India during 2001 through 2014, and epidemiologic investigations implicated bat-borne and human-to-human transmission. (cdc.gov)
Since 2006, the Institute of Epidemiology, Disease Control, and Research in Dhaka, Bangladesh, under the Ministry of Health and Family Welfare of Bangladesh, has collaborated with the International Centre for Diarrhoeal Diseases Research, Dhaka, on hospital-based encephalitis surveillance in the areas where Nipah virus-associated outbreaks have been reported. (cdc.gov)
Upwards of 70% who contract Nipah die from seizures, coma and encephalitis (brain swelling). (dailycaller.com)

With the maximum incubation period reported for similar Nipah virus strains circulating in Kerala found to be 17 days, Kerala's standard operating procedure allowed for a potential incubation period of 21 days. (gavi.org)
Not only the system, but the people also learnt from recurrent outbreaks of Nipah," says TS Anish, professor at the Department of Community Medicine at the Government Medical College, Manjeri, Kerala. (gavi.org)
India has curbed public gatherings and shut some schools in the southern state of Kerala after two people died of Nipah, a virus from bats or pigs that causes deadly fever, officials said on September 14. (dailycaller.com)
At least four additional people have tested positive and are receiving treatment for the virus, which is currently plaguing the state of Kerala, according to Reuters. (dailycaller.com)

The initial case in human outbreaks of Nipah virus has always been zoonotic from exposure to contaminated secretions or tissues of infected bats or pigs. (wikipedia.org)

Until 2004, identification of Nipah virus (NV)-like outbreaks in Bangladesh was based on serology. (cdc.gov)

The World Health Organization (WHO) classifies the Nipah virus (NiV) as a zoonotic virus - it can be transmitted from animals to humans. (smartparenting.com.ph)
Nipah is a zoonotic virus, so can spread between humans and animals with ease, according to the Centers for Disease Control and Prevention (CDC). (dailycaller.com)
Nipah virus is a zoonotic virus, meaning it can be transmitted from animals to humans. (thecomputech.co.in)
Nipah virus (NiV) is a zoonotic virus (it is transmitted from animals to humans) and can also be transmitted through contaminated food or directly between people. (blessbpeprah.com)

Infected people initially develop symptoms that include fever, headaches, myalgia, vomiting and sore throat. (wikipedia.org)
What are the symptoms of the Nipah virus? (smartparenting.com.ph)
Symptoms include fever, headache, sore throats and general sickness, but can get a lot worse. (dailycaller.com)
Some of those infected don't show symptoms until months or even years after exposure to the virus, making it one of the most insidious known to man. (dailycaller.com)
Same cold virus, but different symptoms, what is this? (healthtap.com)
What r some symptoms of west nile virus? (healthtap.com)
What are the symptoms of affected with virus? (healthtap.com)
What are d symptoms of h1n1 virus? (healthtap.com)
What is Nipah virus and its symptoms? (blessbpeprah.com)
Symptoms typically appear in 4-14 days following exposure to the virus. (blessbpeprah.com)

They found that - as well as being a novel virus that didn't originate in humans - it was most closely linked to coronaviruses they had already found in bats. (bbc.com)
Higher levels of oral shedding of the Bangladesh strain of Nipah virus might be a key factor in onward transmission in outbreaks among humans. (nih.gov)
Stress is known to increase virus shedding in many animal species - be it herpes in humans or Nipah in bats. (gavi.org)
They also harbor many other viruses that are thought to have caused disease in humans after spillover into intermediate hosts, including SARS and MERS coronaviruses. (mdpi.com)
These challenges can be addressed, in part, with new technologies that are species-independent that can provide insight into the interactions of bats and viruses, which should clarify how the viruses persist in nature, and what risk factors might facilitate transmission to humans and livestock. (mdpi.com)
Where do viruses dangerous to humans come from, and how have they evolved? (sciencedaily.com)
Just as with influenza, where we are keeping an eye on birds as a source of new pandemic viruses, we will now have to study the bat viruses to see if they are a danger to humans. (sciencedaily.com)
In one case, the scientists have already found proof that bat viruses transfer directly to humans. (sciencedaily.com)
Although antibodies to NV were detected in fruit bats from the affected areas in 2004, an intermediate animal host was not identified, which suggests that the virus was transmitted from bats to humans. (cdc.gov)
They said an infected bat could have been kept in a cage next to a civet in a market with the civet becoming infected and passing the virus to humans. (247wildlife.com)
When human activities lead to changed landscapes, new ecosystem configurations may entail, subsequently increasing potential for unprecedented contact between humans and wildlife, including species carrying human pathogens. (gbif.org)
Nearly twenty species of Leishmania, often responsible for severely disfiguring lesions in humans, are parasites of a variety of animals including sloths, gerbils, hyrax species and domestic dogs. (animalresearch.info)
The consumption of "forest foods" such as bush meat provides ideal conditions for viruses to cross from animals to humans. (animalresearch.info)
Humans can become infected with Nipah virus through contact with infected animals or their bodily fluids, or through contact with contaminated food or water. (thecomputech.co.in)
The same bat that hosts the Handra virus can also harbour the Nipah virus and contaminate the food of the pig, which, by coughing, spreads the virus around it contaminating humans. (ouvry.com)

As of May 2018 about 700 human cases of Nipah virus were estimated to have occurred, and 50 to 75 percent of those infected died. (wikipedia.org)

The disease is named after a village in Malaysia, Sungai Nipah. (wikipedia.org)
It takes its name from the Malaysian village of Sungai Nipah where the first sick farmers came from. (ouvry.com)

The Nipah virus incubation period is 4-14 days. (thecomputech.co.in)

Tropical regions have a rich array of biodiversity, which means they are also home to a large pool of pathogens, increasing the chances that a novel virus could emerge. (bbc.com)
NIAID's Pandemic Preparedness Plan , published earlier this year, established a framework to study viruses of pandemic potential and prioritize research on prototype pathogens, such as Nipah virus. (nih.gov)
China and Viruses: The Case of Dr. Xiangguo Qiu ," a January 2020 paper by Israeli molecular biologist Dr. Dany Shoman, revealed that Dr. Qiu, shipped a cargo of deadly pathogens to the Wuhan lab. (frontpagemag.com)

India has faced six Nipah outbreaks since 2001. (gavi.org)
An NV-like virus was identified as the cause of the outbreaks in 2001 and 2003 on the basis of serologic testing ( 12 ). (cdc.gov)
In Siliguri, India in 2001, transmission of the virus was also reported within a health-care setting, where 75% of cases occurred among hospital staff or visitors. (blessbpeprah.com)
In 2001 an epidemic broke out in Bangladesh with a Nipah virus genetically different from the previous one. (ouvry.com)

During the later outbreaks in Bangladesh and India, Nipah virus spread directly from human-to-human through close contact with people's secretions and excretions. (blessbpeprah.com)

Human infections with Nipah virus in Malaysia and Bangladesh are associated with markedly different patterns of transmission and pathogenicity. (nih.gov)

Our data show that the human mumps virus comes directly from bats -- and can be found there to this day," reported Prof. Drosten. (sciencedaily.com)
The Nipah virus is a member of the Paramyxoviridae family of viruses, which also includes the measles virus and the mumps virus. (thecomputech.co.in)
It is an RNA virus belonging to the large Paramyxoviridae family in the same way as the mumps virus or the measles virus. (ouvry.com)

From India,my eyes came dangerously close to a bat at night 4 days ago.I ducked but am very scared about Nipah virus. (healthtap.com)
Nipah virus outbreaks have since been reported in Bangladesh, India, and the Philippines. (thecomputech.co.in)
It is the Kerela region of India, which is currently under attack from a particularly virulent virus. (ouvry.com)

A virus that is very similar to the deadly Nipah and Hendra viruses has been discovered in fruit bats in Australia and researchers are hoping it can help them find ways to fight those highly dangerous cousins. (medicaldaily.com)
Nipah virus is a serious and potentially deadly disease. (thecomputech.co.in)
This deadly "emerging" virus is harmless to its natural host, the bat. (ouvry.com)

The virus was isolated and identified in 1999. (wikipedia.org)
The Nipah virus was first recorded in Malaysia in 1999. (smartparenting.com.ph)
Nipah virus was first identified in 1999 in Malaysia. (thecomputech.co.in)

HPIVs primarily affect young children, in whom the pathogenic spectrum includes upper and lower respiratory tract infections. (medscape.com)
Chimpanzees, macaques, squirrels, owls, and rhesus monkeys have been asymptomatically infected with HPIV-3 or HPIV-4, and only marmosets have developed symptomatic upper respiratory tract infections (URTIs) with HPIV-3 and Sendai virus. (medscape.com)
While most scientists agree that the new coronavirus probably originated in animals before making the leap to human infections, two Chinese researchers published a report in February which theorised that the virus could have leaked from a laboratory in Wuhan. (scmp.com)
1. Ascertain the viral ecology of disease and factors mediating the emergence of VSV, including the characterizing epidemiological factors associated with the maintenance of disease in endemic versus non-endemic settings (ABADRU) and (FADRU), determining the environmental conditions that influence vector dominance in endemic versus non-endemic settings, and identifying environmental-vector interactions responsible for the emergence of viral infections in new geographical locations. (usda.gov)
Ecology studies in the sw US will be expanded to include endemic areas in Mexico and environmental-vector interactions responsible for the emergence of viral infections in new geographical locations. (usda.gov)
Since early 2017, there has been an increase in Measles cases which has affected 1 in 4 European countries and caused over 20,000 infections, including 35 deaths. (iamat.org)
Bush meat is still popular and continues to be responsible for occasional epidemics of other viral infections including monkeypox. (animalresearch.info)
The findings highlight the possibility that the Malaysia outbreaks had two origins of Nipah virus infections. (upm.edu.my)

Preventive measures include avoiding exposure to bats and infected animals such as pigs, and not drinking raw date palm sap. (wikipedia.org)
In Malaysia and Singapore, Nipah virus infected people with close contact to infected pigs. (wikipedia.org)
Nipah viruses from pigs from a Malaysian 1998 out-break were isolated and sequenced. (upm.edu.my)
The virus can also cause severe disease in animals such as pigs, resulting in significant economic losses for farmers. (blessbpeprah.com)

The Nipah virus (NiV) is a type of RNA virus in the genus Henipavirus, which normally circulates among fruit bats of the genus Pteropus. (wikipedia.org)
To further investigate the distribution of this new group of viruses, we investigated the prevalence of virus antibodies in other members of the genus Pteropus in Cambodia. (medscape.com)
Cite this: Antibodies to Nipah-Like Virus In Bats (Pteropus lyeli), Cambodia - Medscape - Sep 01, 2002. (medscape.com)
Fruit bats (genus Pteropus), also known as the flying fox, are considered the animal host reservoir for the Nipah virus. (smartparenting.com.ph)
Pteropus bats are also known to occasionally shed Nipah virus in their secretions and excretions. (cdc.gov)

It's a major concern because there's no treatment… and a high mortality rate [is] caused by this virus," says Wacharapluesadee. (bbc.com)
Nipah virus is a highly contagious virus, and the mortality rate is high. (thecomputech.co.in)

How the Nipah virus spreads Fruit bats are the natural reservoirs of Nipah virus During acute and convalescent stages of the disease, RNA can be detected using reverse transcriptase polymerase chain reaction (RT-PCR) from throat swabs, cerebrospinal fluid, urine and blood analysis. (wikipedia.org)
Animals that act as reservoirs carry and spread a virus without themselves becoming ill. (247wildlife.com)

Bats are reservoir hosts of several high-impact viruses that cause significant human diseases, including Nipah virus, Marburg virus and rabies virus. (mdpi.com)

Nipah virus poses a considerable pandemic threat because it mutates relatively easily, causes disease in a wide range of mammals, can transmit from person-to-person, and kills a large percentage of the people it infects," said NIAID Director Anthony S. Fauci, M.D. "The need for a preventive Nipah virus vaccine is significant. (nih.gov)
Newcastle disease virus is a rubulavirus that infects poultry, penguins, and other birds and has been responsible for conjunctivitis in bird handlers and laboratory workers. (medscape.com)
Recognizing the potential for new pathways of transmission, the authors investigated other possible exposures to Nipah virus by applying epidemiologic and anthropological approaches in the study of these 3 Nipah virus disease clusters. (cdc.gov)
Manmeet has been working on development of animal model to study Nipah virus neurological disease. (nih.gov)
This results in an urgent need to conduct medical studies in Africa," said the Bonn virologist, adding that many disease cases on this continent remain unexplained and might possibly have been caused by such new viruses. (sciencedaily.com)
4. Establish research program on Crimean Congo Hemorrhagic Fever (CCHF) and Nipah Virus Disease (NiVD), including development of detection and diagnostic in vectors and hosts as well as studying mechanisms of inter-species transmission. (usda.gov)
Virus isolation was performed in the BSL-4 laboratory at the Centers for Disease Control and Prevention in Atlanta. (cdc.gov)
A broad spectrum therapeutic that can target multiple virus families would have a significant impact on disease burden in endemic areas. (nature.com)
Although Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people, making it a public health concern. (blessbpeprah.com)
Lymphocytic choriomeningitis virus is an underreported cause of miscarriage and neurologic disease. (cdc.gov)
We describe a case of acute lymphocytic choriomeningitis virus disease in a person living with HIV in Connecticut, USA, identified by using quantitative reverse transcription PCR. (cdc.gov)

So, the current data might play a useful role in early detection and prevention of epidemics -- a major new goal in virus research. (sciencedaily.com)

As is usual with reservoir hosts, these viruses apparently cause little or no pathology in bats. (mdpi.com)
For bats provide a reservoir from which viruses could come back after vaccination campaigns. (sciencedaily.com)
This would support the idea that bats are the reservoir -- the natural host -- of the virus. (247wildlife.com)
Animals such as palm civets were found to be infected but study showed they were not the true reservoir of the SARS virus. (247wildlife.com)
also known as flying foxes-and whether these changes are associated with Hendra virus spillover events, i.e when a virus passes from a reservoir to a novel species. (gbif.org)

Now, some experts predict the tech will lead to new vaccines against viruses from seasonal influenza to HIV. (nationalgeographic.com)
Some experts see mRNA vaccines as the key to faster or more effective vaccine programs, tackling multiple viruses with a single shot or providing protection against difficult diseases. (nationalgeographic.com)
In January, Moderna pledged new programs to develop mRNA vaccines against Nipah virus, HIV, and influenza, adding to its vaccine pipeline that already included more than 20 mRNA efforts. (nationalgeographic.com)
Pfizer is also working on additional mRNA-based vaccines, including one for seasonal influenza, says Phil Dormitzer , the company's chief scientific officer and vice president of viral vaccines. (nationalgeographic.com)
Traditional vaccines use weakened viruses or viral protein fragments to teach the immune system to recognize and fight an invader. (nationalgeographic.com)
In the Moderna and Pfizer-BioNTech COVID-19 vaccines, that ingredient is the sequence that codes for the coronavirus's spike protein, which is what allows the virus to enter human cells. (nationalgeographic.com)
There are a number of Nipah virus vaccines in development, but none are yet available for widespread use. (thecomputech.co.in)

Some people can also experience atypical pneumonia and severe respiratory problems, including acute respiratory distress. (wikipedia.org)
The importance of bat origin of Corona and other viruses was found only after SARS (Severe Acute Respiratory Syndrome) in 2003. (colombotelegraph.com)
A 1′-cyano substituted adenine nucleoside analog GS-441524 ("Nuc") was shown to have activity against HCV, dengue virus (DenV), parainfluenza type 3 virus (hPIV3), and severe acute respiratory syndrome coronavirus (SARS-CoV) 3 . (nature.com)
Together with the Hendra virus (responsible for acute equine respiratory syndrome), it forms the genus Henipavirus . (ouvry.com)

Measles is a highly contagious virus that can be spread easily through coughing and sneezing, as well as direct contact with an infected person's saliva or nasal secretions. (iamat.org)

Fruit bats are the natural host for the virus. (nih.gov)

To compare the 2 strains, we conducted an in vivo study in which 2 groups of ferrets were oronasally exposed to either the Malaysia or Bangladesh strain of Nipah virus. (nih.gov)
At least two different Nipah virus strains, including a previously unreported strain, were identified. (upm.edu.my)

The experimental mRNA-1215 Nipah virus vaccine will be tested in a dose-escalation clinical trial to evaluate its safety, tolerability, and ability to generate an immune response in 40 healthy adults ages 18 to 60 years. (nih.gov)
When used in a vaccine, mRNA is a mobile molecule that delivers instructions to our bodies to make the components of a virus that will trigger an immune response. (nationalgeographic.com)
With mRNA, scientists can go from "discovering the sequence of the virus to having something in a vial within weeks," says Anna Durbin , a professor of international health at Johns Hopkins Bloomberg School of Public Health in Maryland. (nationalgeographic.com)

On 9 September 2023, a case of suspected Nipah was reported in Kozhikode district. (gavi.org)

Most cases stem from infected bats and flying foxes, with scientists now fearing the virus may have mutated into a far more transmissible strain. (dailycaller.com)
COVID-19 is new strain of the virus), different types of corona infect bats, which appear to co-evolve with the viruses. (colombotelegraph.com)
We confirmed the activity of Nuc against wild-type EBOV (Makona strain), NiV (Malaysian and Bangladesh genotypes) and Hendra virus (HeV) using assays which measured inhibition of virus antigen expression, virus-induced cytopathic effect (CPE) (for NiV and HeV), and virus titer ( Supplementary Figures 2-4 , Supplementary Table 1 ). (nature.com)

Complications can include inflammation of the brain and seizures following recovery. (wikipedia.org)

Nipah virus (NiV) antigen in ferret infected with NiV-Malaysia. (cdc.gov)

Subsequent human-to-human transmission of Nipah virus occurs via close contact with NiV-infected persons or exposure to NiV-infected body fluids (e.g., blood, urine, nasal secretions). (wikipedia.org)
Predicted means for detection of Nipah virus (NiV) RNA in nasal wash samples (A), oral swab samples (B,) and rectal swab samples (C) from experimentally infected ferrets over time, based on residual maximum-likelihood analysis. (nih.gov)

The illness initially presents as 3-14 days of fever and headache, and often includes signs of respiratory illness, such as cough, sore throat, and difficulty breathing . (blessbpeprah.com)

Parainfluenza viruses (PIVs) are paramyxoviruses of the order Mononegavirales, the family Paramyxoviridae, and the subfamily Paramyxovirinae. (medscape.com)
Nipah virus (NV) and Hendra virus (HV), the only members of the genus Henipavirus within the family Paramyxoviridae are different from most other paramyxoviruses because they have a broad host range in vivo and in vitro. (cdc.gov)

We study the pathogenesis of SARS-CoV-2, Nipah virus, and the 1918 influenza H1N1 virus in animal models and human lung organoids. (nih.gov)
Her research there focused on the replication, pathogenesis, and transmission of influenza A virus. (nih.gov)
Gayatri is currently developing a drug-screening model for emerging respiratory viruses using SARS-CoV-2 and Influenza A viruses and targeting the Golgi, a critical site for viral replication and innate immunity. (nih.gov)

In severe cases, Nipah virus can lead to coma and death. (thecomputech.co.in)

Close contact with an infected person' secretions and excretions, which is commonly seen in families and caregivers of Nipah virus-infected patients and in healthcare settings. (smartparenting.com.ph)

These conditions include common cold with fever, laryngotracheobronchitis (croup), bronchiolitis , and pneumonia . (medscape.com)
A combination of climate change, urbanization, and increases in international air travel have accelerated the global spread of many mosquito-borne viruses including Yellow Fever, Zika, Dengue, and Chikungunya. (iamat.org)

Most experts do not classify Nipah virus as airborne, though there is consensus that transmission can-and does-occur from short-range exposure to NiV-infected respiratory droplets in close contact settings. (wikipedia.org)

Samples were sent to the National Institute of Virology (NIV), Pune, India's apex reference laboratory for major virus outbreaks, for confirmation. (gavi.org)
By the 15 September , India's Ministry of Health had reported six laboratory-confirmed Nipah virus cases, including two deaths, in the same district, the World Health Organization stated . (gavi.org)
While the article in The Washington Post highlighted potential concerns about staff training and weak management at the institute, other safety failures could include lapses in containment, including for laboratory waste disposal, and risk assessments for lab experiments, Lentzos said. (scmp.com)

Watch a short film about the viruses that pose the greatest threat of causing a pandemic on BBC Reel. (bbc.com)
In May of 2022, after all the ravages of the pandemic, Lawrence Tabak admits that, at the request of China, the NIH concealed crucial data about the origin of Covid virus. (frontpagemag.com)

Colorized transmission electron micrograph of mature extracellular Nipah Virus particles (red) near the periphery of an infected VERO cell (green). (nih.gov)
Investigations of Nipah virus-associated outbreaks in Bangladesh identified consumption of fresh date palm sap as the primary route of bat-to-human transmission. (cdc.gov)
Human-to-human transmission of Nipah virus has also been reported among family and care givers of infected patients. (blessbpeprah.com)

Here we report the antiviral activities of GS-5734 and the parent nucleoside analog across multiple virus families, providing evidence to support new indications for this compound against human viruses of significant public health concern. (nature.com)

However, she said, none of the genomic sequences from the new virus matched the samples taken by her team from bat caves in China. (scmp.com)

We disrupt ecosystems, and we shake viruses loose from their natural hosts. (colombotelegraph.com)

Our results suggest that the virus circulating in Cambodia is neither Nipah nor HeV, but another closely related virus. (medscape.com)
HPIV is closely related to Hendra virus, Nipah virus, and metapneumoviruses. (medscape.com)

Anatomy3

Organisms30

Diseases8

Chemicals and Drugs12

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes10

Anthropology, Education, Sociology and Social Phenomena1

Information Science2

Health Care3

Geographicals2

Ebola10

Infection32

Outbreak10

Hendra and Nipah4

Encephalitis4

Kerala4

Outbreaks of Nipah virus1

Identification of Nipah virus1

Zoonotic virus4

Symptoms10

Humans15

20181

Sungai Nipah2

Incubation period1

Pathogens3

20014

Bangladesh and India1

Malaysia and Bangladesh1

Mumps3

India3

Deadly3

19993

Infections8

Pigs4

Pteropus5

Mortality rate2

Reservoirs2

Marburg1

Disease11

Epidemics1

Reservoir5

Vaccines7

Acute4

Highly contagious virus1

Fruit1

Strains2

MRNA3

Kozhikode1

Strain3

Seizures1

Antigen1

Nasal2

Sore1

Paramyxoviridae2

Influenza3

Coma1

Secretions1

Fever2

Airborne1

Laboratory3

Pandemic2

Transmission3

Public health concern1

Genomic1

Hosts1

Closely related2