• The Epstein-Barr virus M81 strain, isolated from a nasopharyngeal carcinoma, induces potent spontaneous virus production in infected B cells. (nature.com)
  • Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas. (nature.com)
  • Young, L. S., Yap, L. F. & Murray, P. G. Epstein-Barr virus: more than 50 years old and still providing surprises. (nature.com)
  • Lerner, M. R., Andrews, N. C., Miller, G. & Steitz, J. A. Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus. (nature.com)
  • Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Epstein-Barr Virus (HHV-4) Infections - Drugs In Development, 2021, provides an overview of the Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline landscape.Epstein-Barr virus (EBV) or human herpes virus 4 virus is a member of the Herpesviridae family. (marketresearch.com)
  • Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Epstein-Barr Virus (HHV-4) Infections - Drugs In Development, 2021, provides comprehensive information on the therapeutics under development for Epstein-Barr Virus (HHV-4) Infections (Infectious Disease), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (marketresearch.com)
  • The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.The Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline guide also reviews of key players involved in therapeutic development for Epstein-Barr Virus (HHV-4) Infections and features dormant and discontinued projects. (marketresearch.com)
  • Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (marketresearch.com)
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Epstein-Barr Virus (HHV-4) Infections (Infectious Disease). (marketresearch.com)
  • The pipeline guide reviews pipeline therapeutics for Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) by companies and universities/research institutes based on information derived from company and industry-specific sources. (marketresearch.com)
  • The pipeline guide reviews key companies involved in Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) therapeutics and enlists all their major and minor projects. (marketresearch.com)
  • The pipeline guide evaluates Epstein-Barr Virus (HHV-4) Infections (Infectious Disease) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (marketresearch.com)
  • Atomic structure of the Epstein-Barr virus portal. (csic.es)
  • The Epstein-Barr Virus ( EBV ), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalovirus ), and is one of the most common viruses in humans . (wikidoc.org)
  • We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand mechanisms of virus immune evasion and their implications in disease outcome mainly in HIV and HCV infections, but not limited to them. (hindawi.com)
  • CMV shares many attributes with other herpes viruses, including genome, virion structure, and the ability to cause latent and persistent infections. (medscape.com)
  • NK cells controlling virus-specific T cells: Rheostats for acute vs. persistent infections. (umassmed.edu)
  • Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. (umassmed.edu)
  • Herpes and shingles are both caused by members of the Herpesviridae family of viruses, which can establish latent infections that remain dormant before reactivating at a later time under certain conditions. (lifeextension.com)
  • In this protocol, you will learn about the viruses that cause herpes and shingles, and how these infections are conventionally treated. (lifeextension.com)
  • Although there is no effective cure for herpes virus infections, several natural interventions may help reduce the frequency of outbreaks. (lifeextension.com)
  • Herpesviridae is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. (xshotpix.com)
  • Respiratory tract infections caused by some viruses with cattle origin have been demonstrated in sheep and goats. (ac.ir)
  • A slow virus, BK establishes latent infections in B-lymphocytes and attacks an immunosuppressed host upon reactivation. (stanford.edu)
  • Marek's disease virus (MDV) is a cell-associated alphaherpesvirus belonging to the genus Mardivirus . (uoguelph.ca)
  • Alphaherpesvirinae contains the human herpes simplex viruses types 1 and 2, which are grouped in the genus Simplexvirus, along with bovine mamillitis virus and spider monkey herpesvirus. (xshotpix.com)
  • In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established Herpesvirus as a genus with 23 viruses among four groups. (xshotpix.com)
  • Human Cytomegalovirus (CMV) is a member of the family Herpesviridae, also known as Human Herpesvirus 5 (HHV-5). (medscape.com)
  • Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the Herpesviridae family. (medscape.com)
  • is a member of the herpesvirus family, which also includes viruses that cause cold sores (herpes simplex type 1), genital ulcers (herpes simplex type 2), and shingles (herpes zoster) and the cytomegalovirus. (xshotpix.com)
  • Viruses such as Varicella zoster ( chickenpox ) and Herpesviridae ( herpes simplex viruses, Varicella-Zoster virus, cytomegalovirus etc ) can hide from the immune system in neurons and non-neuronal cells where they may persist for many years, before emerging in pathogenic form when the host has a lowered resistance. (immunology.org)
  • Estimated dates for branching events in the development of reptilian, avian, and mammalian Alphaherpesvirinae lineages could plausibly be accounted for in part but not completely by ancient coevolution of these virus lines with reptilian lineages and with the development of birds and mammals from reptilian progenitors. (lancs.ac.uk)
  • It is increasingly clear that DNA viruses exploit cellular epigenetic processes to control their life cycles during infection. (mdpi.com)
  • For each type of virus, what is known about the roles of DNA methylation, histone modifications, nucleosome positioning, and regulatory RNA in epigenetic regulation of the virus infection will be discussed. (mdpi.com)
  • Presence of nucleic acid or antigen in semen does not represent the presence of replication-competent or infection-competent virus, which can generally only be demonstration by isolation and culture of virus. (cdc.gov)
  • Maximum detection time refers to time from symptom onset (only in viruses that cause acute only, not chronic, infection). (cdc.gov)
  • Most horses have been infected with EHV-1, but the virus can become latent and persist without ever causing signs of infection. (wikipedia.org)
  • Some horses may be asymptomatic upon infection increasing the difficulty in controlling the spread of the virus. (wikipedia.org)
  • Upregulation of PD-1 and its ligands PD-L1 and PD-L2 is observed during acute virus infection and after infection with persistent viruses including important human pathogens such as human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV). (frontiersin.org)
  • Virus excretion begins approximately 2 weeks post infection and continues indefinitely with maximum shedding 3-5 weeks after initial infection. (uoguelph.ca)
  • Once the virus is introduced into a chicken flock, infection spreads quickly from bird to bird, regardless of vaccination status or genetic resistance. (uoguelph.ca)
  • Control is a challenge due to ubiquitous virus, latent infection, continuous viral shedding, and long-term survival of virus in the environment. (uoguelph.ca)
  • Vaccines do NOT prevent infection but they do protect against early replication of virulent viruses in lymphoid organs, and reduce the level of latent infection. (uoguelph.ca)
  • Herpes simplex virus 1 (HSV-1) is a double-stranded DNA virus that proliferates in the nuclei of host cells during lytic infection (reviewed in reference 1). (xshotpix.com)
  • Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infection in infants and children and the second most common viral cause of pneumonia in adults. (medscape.com)
  • Influenza pneumonia: Amantadine hydrochloride and rimantadine hydrochloride are approved for the prevention and treatment of influenza A virus infection. (medscape.com)
  • Diagnostic Automation HSV1 IgA elisa test kit is intended for use in evaluating a patient's serologic status to Herpes Simplex Virus (HSV) infection, or for evaluating paired sera for the presence of a significant increase in herpes specific IgA. (rapidtest.com)
  • Failure to correctly diagnose and provide immediate treatment for varicella zoster virus (VZV) infection in pregnant patients can lead to life-threatening complications for the mother, and serious congenital malformations to the fetus. (jucm.com)
  • Herpes viruses infection transmitted through healthy but infected blood donors pose a danger to herpes-naive immunocompromised recipients. (biomedcentral.com)
  • Interferon-inducing properties of dry birch bark extract and its effect on experimental infection caused by hepatitis C virus]. (nih.gov)
  • Dr. Streblow's lab has also generated a rhesus macaque (RM) chikungunya virus (CHIKV) infection animal model to identify correlates of CHIKV pathogenesis and to test novel antivirals and vaccines. (ohsu.edu)
  • Zika Virus infection of rhesus macaques leadsto viral persistence in multiple tissues. (ohsu.edu)
  • Animal Models of Chikungunya Virus Infection and Disease. (ohsu.edu)
  • Viruses modulate biochemical cellular pathways to permit infection. (ucp.pt)
  • This deficiency was confirmed under physiological conditions, on infection of mice with a murine gammaherpesvirus 68 chimera expressing LANA, where the virus was highly deficient in establishing latent infection in germinal center B cells. (ucp.pt)
  • Nipah virus infection causes febrile encephalitis and aseptic meningitis. (stanford.edu)
  • A relativiely quick virus, clinical manifestations of Nipah infection occur shortly after handling infected pigs. (stanford.edu)
  • It is postulated that following natural infection with EBV, the virus executes some or all of its repertoire of gene expression programs to establish a persistent infection. (wikidoc.org)
  • Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established 1 . (northwestern.edu)
  • This principle of viral assimilation may prove relevant to other virus families and offers new strategies to combat infection. (northwestern.edu)
  • The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
  • None of the therapies used as treatment gives a cure to the viral infection, once the drugs only have their effect during the virus active phase. (bvsalud.org)
  • As members of the Herpesviridae virus family, there are two strains of the herpes simplex virus, HSV-1, which is responsible for cold sores, and HSV-2, which is responsible for genital herpes. (eol.org)
  • This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous herpes simplex type-2 virions, members of the Herpesviridae virus family. (eol.org)
  • Equid alphaherpesvirus 1, formerly Equine herpesvirus 1 (EHV-1), is a virus of the family Herpesviridae that causes abortion, respiratory disease and occasionally neonatal mortality in horses. (wikipedia.org)
  • The other family members include herpes simplex virus type 1 (HSV-1 or HHV-1) and herpes simplex virus type 2 (HSV-2 or HHV-2), varicella zoster virus (VZV), human herpes virus (HHV)-6, HHV-7, and HHV-8. (medscape.com)
  • Which is a member of the herpes virus family? (xshotpix.com)
  • They all come from the large Herpesviridae family of DNA viruses that affect humans. (xshotpix.com)
  • Herpes Simplex Virus (HSV) also known as Human herpes virus is a member of the herpes virus family, Herpesviridae. (rapidtest.com)
  • VZV is a DNZ virus, part of the herpes virus family, and is highly contagious. (jucm.com)
  • KHV, now formally known as Cyprinid Herpes Virus 3 or CyHV-3, is a member of the Herpesviridae family and has been responsible for mass mortalities in carp around the world, with Israel, Japan and South Africa particularly hard hit. (practicalfishkeeping.co.uk)
  • This image is composed of a montage of six transmission electron microscopic (TEM) images of viruses that are members of the Herpesviridae family including the chickenpox varicella zoster virus (VZV), also known as Human herpesvirus 3 (HHV-3), and herpes simplex virus, type 1 and 2 (HSV-1, HSV-2). (cdc.gov)
  • DNA virus member of Herpesviridae family. (hopkinsguides.com)
  • Machón C Fàbrega-Ferrer M, Zhou D, Cuervo A, Carrascosa JL, Stuart DI, Coll M Abstract Herpesviridae is a vast family of enveloped DNA viruses that includes eight distinct human pathogens, responsible for diseases. (csic.es)
  • Belongs to the herpesviridae NEC1 protein family. (expasy.org)
  • I'm part of the Herpesviridae family. (blogspot.com)
  • Varicella-Zoster Virus (VZV) belongs to the family Herpesviridae. (bvsalud.org)
  • The human herpes viruses (HHV) take part of a virus family - Herpesviridae- and these viruses have human as only host. (bvsalud.org)
  • These observations provide a mechanistic molecular link between M81 virus replication-a central viral function and a cancer risk factor-and the production of a chemokine involved in inflammation and carcinogenesis. (nature.com)
  • In spite of their broad abundance, viruses, in particular bacteriophages, remain largely unknown since only about 20% of sequences obtained from viral community DNA surveys could be annotated by comparison with public databases. (mdpi.com)
  • In order to shed some light into this genetic dark matter we expanded the search of orthologous groups as potential markers to viral taxonomy from bacteriophages and included eukaryotic viruses, establishing a set of 31,150 ViPhOGs (Eukaryotic Viruses and Phages Orthologous Groups). (mdpi.com)
  • The influenza viruses are the most common viral cause of pneumonia. (medscape.com)
  • Special Topic AIDS Servers Clinical AIDS and Patient Care Resources Clinical Trials Information Educational/Sociological AIDS Resources Legal Issues Surrounding AIDS Other Lists of WWW AIDS Sites Alternative Views of AIDS Usenet Newsgroups Related to AIDS Emerging Viruses Information/Research Other Health Organizations Disease Servers (Viral? (bio.net)
  • Internal R&D project implementing an excipient preselection approach, enabling rational formulation development and the generation of best-in-class formulations for Ad5 viruses and viral vectors in liquid. (leukocare.com)
  • Herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2) cause oral and genital herpes, and varicella-zoster virus causes chickenpox in children and shingles later in life. (lifeextension.com)
  • Johns Hopkins Guides , www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540579/all/Varicella_zoster_virus. (hopkinsguides.com)
  • Auwaerter P. Varicella-zoster virus. (hopkinsguides.com)
  • Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication. (csic.es)
  • Immunosuppression reactivates BK virus replication and is linked to hemorrhagic cystis in bone marrow transplants. (stanford.edu)
  • In general, MDV refers to Gallid herpesvirus 2 (serotype 1, prototype virus). (uoguelph.ca)
  • 6 Humans are the only hosts of VZV, and the virus infects though nasopharyngeal mucus membranes and conjunctivae. (jucm.com)
  • It is one of the most common human viruses to cause cancer in humans and is associated with a wide range of human cancers originating from epithelial cells, lymphocytes and mesenchymal cells. (marketresearch.com)
  • The classification of this virus can be confusing as it has evolved over time ( Table 1 ), but the original terminology is still in use. (uoguelph.ca)
  • Marek's Disease virus classification. (uoguelph.ca)
  • This review will address epigenetic regulation in members of the polyomaviruses, adenoviruses, human papillomaviruses, hepatitis B, and herpes viruses. (mdpi.com)
  • Among those, RNA viruses such us human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are two of the main challenges for the global health in the 21st century. (hindawi.com)
  • Absence of hepatitis C virus and detection of hepatitis G virus/GB virus C RNA sequences in the semen of infected men. (cdc.gov)
  • I'm a double stranded DNA virus (I'm made up of 2 DNA parts). (blogspot.com)
  • Viruses are the causative agent of multiple infectious diseases and are one of the leading causes of mortality in poor-resource countries. (hindawi.com)
  • The mechanism by which latent viruses, such as genetically transmitted tumor viruses ( PROVIRUSES ) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. (lookformedical.com)
  • Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL). (lookformedical.com)
  • This book is directed toward the molecular composition, pathogenesis, diagnosis, treatment and control of congenital and other related diseases of the newborn that are caused by a variety of viruses. (unicat.be)
  • Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)
  • A general term for diseases produced by viruses. (lookformedical.com)
  • Therefore, to understand the mechanism of virus immune evasion and its implications in disease outcome is crucial to establish the rational basis for new vaccine designs and successful treatment strategies. (hindawi.com)
  • Resurgence of Ebola virus disease in guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days. (cdc.gov)
  • Marek's disease virus is ubiquitous. (uoguelph.ca)
  • Parainfluenza virus (PIV) is second in importance only to RSV as a cause of lower respiratory tract disease in children and pneumonia and bronchiolitis in infants younger than 6 months. (medscape.com)
  • KHV is not yet a notifiable disease in the UK and Cefas now charges a fee to determine whether fish are infected with the virus. (practicalfishkeeping.co.uk)
  • The knowledge of the types of herpes virus, its clinical characteristics and oral manifestations is of paramount importance for the correct diagnosis of the disease to obtain treatment success and, consequently, maintenance of population health. (bvsalud.org)
  • The EBNA-1 protein is essential for maintenance of the virus genome . (wikidoc.org)
  • The findings explain a critical component of the alphaherpesvirus neuroinvasive mechanism and demonstrate that these viruses assimilate a cellular protein as an essential proviral structural component. (northwestern.edu)
  • Deep to the tegument is the icosahedral capsid (pale blue), that contains the DNA genome (red body in centre of virus). (rkm.com.au)
  • CMV has the largest genome of the herpes viruses. (medscape.com)
  • On infecting the B-lymphocyte, the linear virus genome circularizes and the virus subsequently persists within the cell as an episome. (wikidoc.org)
  • The EHV-1 virus can latently infect horses and can reactivate if appropriate conditions appear. (wikipedia.org)
  • Given the initial absence of host immunity , the lytic cycle produces large amounts of virus to infect other (presumably) B-lymphocytes within the host. (wikidoc.org)
  • Molecular evidence of sexual transmission of Ebola virus. (cdc.gov)
  • Moreover, it is suggested that sheep might have a role in the transmission of this virus to cattle. (ac.ir)
  • Although infected horses build some type of immunity through repeated exposure of the virus, there has been no evidence of adaptive immunity to provide protection against the most severe symptoms of EHV-1 including EHM. (wikipedia.org)
  • Eventually, when host immunity develops, the virus persists by turning off most (or possibly all) of its genes, only occasionally reactivating to produce fresh virions. (wikidoc.org)
  • Thus, M81 induced chronic inflammation in its target cells and this resulted in increased virus production. (nature.com)
  • 1. Kulcsár G, Csata S, Nász I. Investigations into virus carriership in human semen and mouse testicular cells. (cdc.gov)
  • Cytologic evaluation: Intranuclear inclusions often exist in cells infected with a deoxyribonucleic acid (DNA) virus. (medscape.com)
  • Cytoplasmic inclusions usually are present in cells infected with a ribonucleic acid (RNA) virus. (medscape.com)
  • Herpes viruses 6 and 8 (HHV-6 and HHV-8) are enveloped ds-DNA viruses that can remain latent in the host cells for a long time. (biomedcentral.com)
  • A study of the antiherpetic activity of the chaga mushroom (Inonotus obliquus) extracts in the Vero cells infected with the herpes simplex virus]. (nih.gov)
  • The latent programs reprogram and subvert infected B-lymphocytes to proliferate and bring infected cells to the sites at which the virus presumably persists. (wikidoc.org)
  • EBNA-1 possesses a glycine - alanine repeat that impairs antigen processing and MHC class I-restricted antigen presentation thereby inhibiting the CD8-restricted cytotoxic T-cell response against virus infected cells. (wikidoc.org)
  • Here, using herpes simplex virus type I and pseudorabies virus as model alphaherpesviruses, we show that a cellular kinesin motor is captured by virions in epithelial cells, carried between cells, and subsequently used in neurons to traffic to nuclei. (northwestern.edu)
  • Process of growing viruses in live animals, plants, or cultured cells. (lookformedical.com)
  • These viruses directly recruit cellular motors for transport along microtubules in nerve axons, but how the motors are manipulated to deliver the virus to neuronal nuclei is not understood. (northwestern.edu)
  • How many types of herpes virus are there? (xshotpix.com)
  • There are currently 8 different types of herpes viruses known today. (xshotpix.com)
  • Herpes simplex virus 1 is a virus responsible for the majority of cold sores and a minority of genital sores, while herpes simplex virus 2 is a virus responsible for the majority of genital sores. (xshotpix.com)
  • Abstract Some viruses package dsDNA together with large amounts of positively. (csic.es)
  • This paper is a review about the human herpes viruses types, their treatments and emphasizes their oral manifestations. (bvsalud.org)
  • The virus can remain latent in infected carriers for long periods and only becomes symptomatic when the temperature rises to 15-28C. (practicalfishkeeping.co.uk)
  • The mechanisms used by certain viruses to dysregulate the host cell through manipulation of epigenetic processes and the role of cellular cofactors such as BRD4 that are known to be involved in epigenetic regulation of host cell pathways will also be covered. (mdpi.com)
  • They are working on developing a Zika virus RM model. (ohsu.edu)
  • The main goal of this study was to determine Bovine Herpes virus type 1 BHV1antigen in formalin-fixed paraffin-embedded lung tissue of pneumonic sheep, using immunohistochemistry (IHC) staining method. (ac.ir)
  • Tumour production is associated only with serotype 1 viruses that vary widely in virulence. (uoguelph.ca)
  • Serotype 1 viruses are further divided into pathotypes based on virulence ( Table 1 ). (uoguelph.ca)