• The enrolment criterion of minimal HSV symptoms may have altered the spectrum of patients included in favour of those with less HSV shedding, although our goal was to document the extent of residual HSV shedding in the least symptomatic HAART-treated persons. (bmj.com)
  • Study termination at the time of a clinical outbreak may have produced lower HSV shedding rates in those with more active HSV, but was uncommon and occurred in both study groups (3 na├»ve and 1 HAART). (bmj.com)
  • Similarly, in sparrows and starlings inoculated with the H5N1 HPAI A/chicken/Hong Kong/220/97 virus, clinical signs were observed only in sparrows, and no deaths occurred ( 9 ). (pubmedcentralcanada.ca)
  • These researchers published their findings about this new virus in 1986. (prohealth.com)
  • The findings suggest that interfering with host cell chaperones could help prevent flu viruses from becoming resistant to existing drugs and vaccines, says Matthew Shoulders, the Whitehead Career Development Associate Professor of Chemistry at MIT. (news-medical.net)
  • The findings pertain to all viruses in the family of flaviviruses which are carried by mosquitoes and ticks. (medindia.net)
  • To confirm their findings, the UCLA team engineered a harmless virus with Nipah virus proteins embedded in its coat. (medica-tradefair.com)
  • Virus shedding was first detected by reverse transcription-PCR (RT-PCR) 18 hours after participant inoculation and lasted a median of 28 days after inoculation (range 13-56 days). (thefreelibrary.com)
  • The median peak amount of virus shedding was 95 x [10.sup.(range 0.5-1,640 x [10.sup. genomic copies/g feces as measured by quantitative RTPCR. (thefreelibrary.com)
  • HSV (type 1 and/or 2) shedding occurred on a median (IQR) of 7.1% (0, 17.9%) of days in HAART users and 3.6% (0, 10.7%) of days in non-HAART users. (bmj.com)
  • Rossmann and his colleagues detailed critical structural changes that take place as the dengue virus moves from the inner to the outer portions of its host cell. (medindia.net)
  • Dengue is a tropical disease caused by mosquitoes carrying the dengue virus. (medindia.net)
  • Ebola virus has been isolated by cell culture from blood, saliva, urine, aqueous humor, semen, and breast milk from infected or convalescent patients. (ovid.com)
  • Ablashi has done research on this virus also and he published in 1995 that "the involvement of Epstein-Barr virus in CFS patients is diminishing. (prohealth.com)
  • Nevertheless, he stated that there could "be a subset of CFS patients in whom Epstein-Barr virus may be a major contributing factor to disease manifestation. (prohealth.com)
  • The new data imply that treating patients with a chaperone-inhibiting drug along with another antiviral therapy, such as a drug or vaccine, could help ensure that the virus does not evolve resistance to the therapeutic. (news-medical.net)
  • Animals spread the virus to people, where it causes life-threatening respiratory and neurological diseases that kill up to 70 percent of patients - a danger level equivalent to the Ebola virus. (medica-tradefair.com)
  • Among researchers who study asthma, there is debate over why patients with this common breathing disorder might have more trouble dealing with airway viruses than people without asthma. (superdoctors.com)
  • Holtzman and his colleagues looked at two common airway viruses - influenza A and respiratory syncytial virus (RSV) - and the interferon response they triggered in airway cells sampled from 11 patients with mild to severe asthma and seven control participants without asthma. (superdoctors.com)
  • To identify differences between antiviral mechanisms in humans and bats, the research team sequenced, assembled, and analyzed the genome of Rousettus aegyptiacus, the Egyptian fruit bat-a natural reservoir of Marburg virus and the only known reservoir for any filovirus. (scienceblog.com)
  • Australian researchers have used current hepatitis B virus (HBV) genome sequences to deduce ancient human population movements into Australia, adding weight to the theory that the mainland Aboriginal population separated from other early humans at least 59 thousand years ago and possibly entered the country near the Tiwi Islands. (heritagedaily.com)
  • Flu viruses carry eight genome segments, all encoded by RNA. (news-medical.net)
  • They found that a protein which coats the genome of the virus particle undergoes large changes in its structure so that it becomes capable of fusing with cell membranes. (medindia.net)
  • Prolonged measles virus shedding did not correlate with levels of measles virus-specific antibody. (lshtm.ac.uk)
  • They also developed an immunoassay that rapidly detects antibody responses to viruses. (usda.gov)
  • It's relatively easy to make a drug that kills a virus, or an antibody that stops a virus from propagating, but it's very hard to make one that the virus doesn't promptly escape from once you start using it,' Shoulders says. (news-medical.net)
  • It is HHV-6B that is associated with roseola and over 90% of adults retain this virus dormant in their system throughout their lives. (prohealth.com)
  • Shedding of the virus is greater from 6-9 month old lambs than from adults. (wikipedia.org)
  • Vaccination could protect these valuable birds and, through reduced virus shedding, reduce risk for transmission to other avian species and humans. (vetscite.org)
  • Diagnostic tests that rapidly detect disease-causing viruses in animals and humans are being developed by U.S. Department of Agriculture (USDA) scientists using a new technology called 'surface-enhanced Raman scattering,' or SERS. (usda.gov)
  • The studies disagree, however, on how easily the virus spreads: One team concludes that it does so very well, but the other believes that it's only moderately adept at jumping from one animal to the next, or, for that matter, between humans. (sciencemag.org)
  • Humans can also be infected with the virus when bitten by these mosquitoes. (eurekalert.org)
  • In a new study published in the open access journal PLoS Biology, Drs. Marm Kilpatrick, Peter Daszak, and colleagues now present evidence that the major vector of West Nile virus in the USA, Culex pipiens mosquitoes, change their feeding behavior in the fall from their preferred host, American robins, to humans, resulting in large scale outbreaks of disease. (eurekalert.org)
  • Professor Beatty noted that similar viruses could cause hepatitis and liver cancers in other species, but that there was no risk to humans or other pets from the newly discovered cat hepadnavirus. (pets4life.com.au)
  • As we were analysing the sequences of HBV isolated as part of this study, we noted that the virus sequences had very strong geographical connections to the communities we visited," said Dr Littlejohn. (heritagedaily.com)
  • In this study, the MIT team investigated whether viruses can take advantage of their host's chaperone proteins to help with their own evolution. (news-medical.net)
  • This is possibly the most detailed understanding of how any virus matures,' said study author Michael Rossmann of Purdue University in Indiana. (medindia.net)
  • A new study found that a man in the United Kingdom, immunized with polio vaccine as a child, has been shedding live virus in his stool for 28 years. (thenextdigit.com)
  • The virus is no different than any other polio virus," said Dr. Javier Martin, biologist at the National Institute for Biological Standards and Control in the U.K and author of the study. (thenextdigit.com)
  • In the new study, the researchers identified 11 new strains of SARS virus and sequenced their full genomes to uncover their evolutionary relationships. (eurekalert.org)
  • They also measured similar amounts of virus living in the cells at various points of time during the study, indicating that the battles against the viruses progressed similarly in both groups. (superdoctors.com)
  • To address this issue, Ben Hu of the Chinese Academy of Sciences in Wuhan, China, and colleagues spent five years studying SARS viruses found in multiple species of horseshoe bats living in a single cave in Yunnan Province, China. (eurekalert.org)
  • We performed an extensive PubMed literature review encompassing the period from discovery of Ebola virus, in 1976, until 1 June 2016 to evaluate the evidence on modes of Ebola virus shedding and transmission. (ovid.com)
  • Scientists have discovered a new cat virus, hepadnavirus in an immunocompromised cat - and subsequently, in banked samples - the domestic cat hepadnavirus is in the same family as hepatitis B virus of people. (pets4life.com.au)
  • From May through September 2005,Dr. Kilpatrick, senior research scientist with the Consortium for Conservation Medicine, and his team collected mosquitoes and caught birds at six sites in Maryland and Washington, D.C. They determined the changes in mosquito populations throughout the West Nile virus transmission season, the abundance and diversity of bird species at these sites, and tested samples for West Nile virus. (eurekalert.org)
  • Apart from its relevance for feline health, this discovery helps us understand how hepatitis viruses - which can be deadly - are evolving in all species," Professor Beatty concluded. (pets4life.com.au)
  • The MIT team found that flu viruses' rapid evolution relies in part on their ability to hijack some of the cellular machinery of the infected host cell -- specifically, a group of proteins called chaperones, which help other proteins fold into the correct shape. (news-medical.net)
  • They found that the virus did indeed evolve faster in the cells with higher chaperone levels than in the cells with inhibited chaperone proteins. (news-medical.net)
  • The debate has centered on the role of proteins called interferons, which are released by cells lining the airways and are so named because they "interfere" with an invading virus. (superdoctors.com)
  • This yellowish or brown crust or scab is not made of active virus but from blood serum containing useful proteins such as immunoglobulins. (wikipedia.org)
  • These feeding shifts appear to be a "continent-wide phenomenon," the researchers conclude, and may explain why West Nile virus outbreaks are so intense in the U.S. compared to Europe and Africa, where the virus originates. (eurekalert.org)
  • Our collaborative team includes ecologists, virologists, and entomologists, and uses state-of-the-art techniques, including DNA sequencing of mosquito blood meals, to piece together what drives a virus to cause outbreaks in people. (eurekalert.org)
  • We aimed to define frequency and characteristics associated with oral shedding of HSV-2. (nih.gov)
  • Understanding of the relevance of prolonged fecal norovirus excretion must await the development of sensitive methods to measure virus infectivity. (thefreelibrary.com)
  • Correlation Between the Interval of Influenza Virus Infectivity and Results of Diagnostic Assays in a Ferret Model. (cambridge.org)
  • From 19 January to 10 June 2016, the team tested 4129 consecutive blood donations and conducted systematic nucleic acid testing for the presence of the Zika virus . (medicalxpress.com)
  • The spread of a virus or a disease has a lot to do with human behavior, and a recent plague in an online game got a few scientists thinking. (npr.org)
  • ARS scientists are using a new technique with gold nanoparticles to design field diagnostic tests for viruses like those that can cause West Nile fever and Rift Valley fever. (usda.gov)
  • Once the scientists identified the virus, they tested stored blood sample from adult pet cats. (pets4life.com.au)
  • When the [white blood cells] come in contact with [brain] cells/tissues, somehow the virus becomes activated, spreads to the CNS and induces CNS manifestations. (prohealth.com)
  • The inoculum, which contained no other enteric viruses or adventitious agents, was packaged and stored at -80[degrees]C. (thefreelibrary.com)
  • The rash usually heals within 10 days, but the virus remains dormant in the facial nerve. (wikipedia.org)
  • But, researchers have found strains of the virus from sewage systems in Isreal, Slovakia, Finland and Estonia, indicating that there might be more people with a similar condition. (thenextdigit.com)
  • The virus is transmitted by Culex mosquitoes (the "vector") and cycles between birds that the mosquitoes feed on. (eurekalert.org)
  • Ten (90.9%) of 11 human immunodeficiency virus (HIV)-infected children had prolonged measles virus shedding, compared with 19 (52.8%) of 36 HIV-uninfected children (P=.02). (lshtm.ac.uk)
  • However, researchers found that the virus was neutralized in lab tests of human blood. (thenextdigit.com)
  • The researchers found no difference in the key immune response to viruses in the lungs and breathing passages. (superdoctors.com)
  • Ultimately, this information will be used to understand correlates of protection in bats and to develop therapeutics against Marburg virus and other lethal filovirus infections. (scienceblog.com)
  • Epidemiologic studies indicate that obesity increases the risk of severe complications and death from influenza virus infections, especially in elderly individuals. (wordpress.com)
  • The researchers infected both sets of cells, plus a group of cells with normal chaperone levels, with a strain of flu and then allowed the virus to evolve for nearly 200 generations. (news-medical.net)
  • People with asthma often have a hard time dealing with respiratory viruses such as the flu or the common cold, and researchers have struggled to explain why. (superdoctors.com)
  • Since its introduction to the United States in 1999, West Nile virus has become the major vector-borne disease in the U.S., with 770 reported deaths, 20,000 reported illnesses, and perhaps around a million people infected. (eurekalert.org)
  • One likely possibility that the group has proposed is that viruses have a special means to induce inflammatory airway disease, and the susceptibility to this process may be an essential feature of asthma and related lung diseases such as chronic obstructive pulmonary disease. (superdoctors.com)
  • BETHESDA, MD. - HIV-infected women have higher rates of human papilloma virus shedding and higher rates of high grade cervical intraepithelial neoplasia, and are diagnosed more frequently with vulvar intraepithelial neoplasia (VIN) than are women who are not infected, Thomas C. Wright Jr., M.D., said at a conference on vulvovaginal diseases. (mdedge.com)
  • A reverse transcriptase-polymerase chain reaction assay was used to detect measles virus RNA in peripheral blood mononuclear cells, urine, and nasopharyngeal specimens from Zambian children during hospitalization and approximately 1-2 months after discharge. (lshtm.ac.uk)