• METHODS AND RESULTS: Here, in using a simian immunodeficiency virus (SIV) infected rhesus macaque model of neuroHIV, we find SIV Nef reactivity in the frontal cortex, hippocampus and cerebellum of SIV-infected animals using immunohistochemistry (IHC). (bvsalud.org)
  • Enteroviruses (EVs) are among the most common human viruses, infecting ≈1 billion persons worldwide annually ( 1 ). (cdc.gov)
  • The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
  • R191 may represent compensatory evolution to restore the ability to downregulate tetherin lost in viruses harboring Q196. (bvsalud.org)
  • Overall changes in the host cellular proteome upon retroviral infection intensify from the initial entry of the virus to the incorporation of viral DNA into the host genome, and finally to the consistent latent state of infection. (medscape.com)
  • Retroviruses encode a limited number of proteins and therefore rely heavily on host factors for virtually every aspect of the viral life cycle. (medscape.com)