• The xTAG(®) Gastrointestinal Pathogen Panel (GPP) is a multiplexed molecular test for 15 gastrointestinal pathogens. (nih.gov)
  • The Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet) is organising a training course on "Introduction to virology, diagnostics and molecular epidemiology on emerging and vector-borne disease viral pathogens" on Wednesday 21 June 2023 and Thursday 22 June 2023 - 13:00-17:00 CEST (Stockholm time). (europa.eu)
  • The Molecular Basis of Viral DNA Sensing through the cGAS-STING Pathway The innate immune response is the first line of defense against invading pathogens. (grantome.com)
  • Unfortunately, diagnostic technology is insufficiently developed to permit determining the disease burden of each of the known viral pathogens. (cdc.gov)
  • Vaginal swab samples were processed, stored, and shipped to the Chronic Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA for analysis. (cdc.gov)
  • Plant Viruses As Molecular Pathogens is the only book to bring you all of this information--22 chapters--in a single volume, compiled by specialists around the globe! (routledge.com)
  • With helpful illustrations, photos, figures, models that explain viral mechanisms, and easy-to-understand reference tables, Plant Viruses As Molecular Pathogens will stimulate your thinking on this fascinating area of plant science! (routledge.com)
  • SARS-CoV-2-PLpro promotes infection by sensing and processing both viral and human proteins, said senior author Shaun K. Olsen, PhD , associate professor of biochemistry and structural biology in the Joe R. and Teresa Lozano Long School of Medicine at UT Health San Antonio. (scienceblog.com)
  • Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead to cirrhosis, cancer, and liver failure. (wjgnet.com)
  • We will also discuss the chemical tools available to study the role of PI4Ks in viral infection . (bvsalud.org)
  • Viral vector vaccines do not cause infection with either the virus used as the vector or the source of the antigen. (wikipedia.org)
  • The detection of viral nucleic acids is a central strategy by which the hosts sense infection and launch protective immune responses. (grantome.com)
  • The proposed studies represent a rigorous and comprehensive investigation into the mechanisms of cytosolic DNA sensing and will dramatically advance our understanding of the molecular basis of innate immunity against viral infection. (grantome.com)
  • Control measures for outbreaks of viral gastroenteritis should focus on the removal of an ongoing common source of infection (e.g., an ill food handler or the contamination of a water supply) and on the interruption of person-to-person transmission that can perpetuate an outbreak in a population after the common source has been removed. (cdc.gov)
  • What Is a Viral Infection? (medicinenet.com)
  • A viral infection is a proliferation of a harmful virus inside your body. (medicinenet.com)
  • With an active viral infection, a virus makes copies of itself and bursts the host cell (killing it) to set the newly-formed virus particles free. (medicinenet.com)
  • Is it a Bacterial or Viral Infection? (medicinenet.com)
  • Contaminated food and water are other potential sources of viral infection. (medicinenet.com)
  • Lecture materials will focus on the molecular basis for virus pathogenesis including host immune responses to virus infection and viral countermeasures. (queensu.ca)
  • Most people with chronic viral hepatitis, however, are not aware of their infection and do not receive appropriate treatment. (who.int)
  • For these people, treatment decisions depend on knowing whether they have a viral or bacterial infection . (medlineplus.gov)
  • The molecular investigations were carried out for the common enteric infection viz. (microbiologyjournal.org)
  • Observations that favor a viral etiology include a clinical presentation similar to that of chronic myocarditis, findings of myocarditis or myocardial fibrosis in affected patients, a higher incidence following epidemics of coxsackievirus B infection, demonstration of persistent viral infection with molecular studies, and experimental production of the disease in animal models by viral infections of the myocardium. (medscape.com)
  • It's not easy to treat viral infections. (kpcw.org)
  • But Pardis Sabeti , head of the lab they work in, is bullish about using the CRISPR Cas13 system to treat viral infections in people. (kpcw.org)
  • Viral infections are still a major threat to human health. (grantome.com)
  • How Long Are Viral Infections Contagious? (medicinenet.com)
  • Viral infections are contagious for varying periods of time depending on the virus. (medicinenet.com)
  • Respiratory viral infections affect the lungs, nose, and throat. (medicinenet.com)
  • Emphasis will be on viral infections that result in gastrointestinal, haematological, neurological, and respiratory diseases. (queensu.ca)
  • It has always been necessary for researchers to visualise pathogenic microorganisms in their host cell's environment, in order to define the host-pathogen interactions contributing to viral infections. (pasteur.fr)
  • Nucleoside analogs ( NA s) are used to treat numerous viral infections and cancer. (plos.org)
  • Nucleoside analogs ( NA s) represent an important drug class for the treatment of viral infections and cancer. (plos.org)
  • American and Polish scientists, reporting Oct. 16 in the journal Science Advances , laid out a novel rationale for COVID-19 drug design - blocking a molecular "scissor" that the virus uses for virus production and to disable human proteins crucial to the immune response. (scienceblog.com)
  • Utilizing computational methodologies, including molecular modeling and conventional molecular dynamics simulations to understand the relationship between the three-dimensional structures, dynamics and the biological functions of DNA-binding enzymes and proteins central to Type I Diabetes. (umassmed.edu)
  • The book contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, synergism with pivotal coverage of RNA silencing, and the counter-defensive strategies used by viruses to overcome the silencing response in plants. (researchandmarkets.com)
  • Here you'll find new and useful information about plant molecular virology and how the field can improve the world food situation in the coming years. (routledge.com)
  • Our viral clearance studies are designed by experts in global regulatory requirements, downstream processing, and virology. (sigmaaldrich.com)
  • antiviral compounds, systems biology of viral hemorrhagic fever, novel approaches to virus detection. (bu.edu)
  • There is a need to review and enhance current protection measures in the field of synthetic biology, whether in experimental laboratories where new advances are being researched, in health care settings where treatments using viral vectors as gene delivery systems are increasingly being used, or in the industrial bioeconomy. (cdc.gov)
  • 1 Program in Structural and Computational Biology and Molecular Biophysics, Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, Texas 77030, USA. (nih.gov)
  • The last decade has seen remarkable advances in plant virological research, owing mainly to the rapid progress made in molecular biology and genetic engineering in recent years. (routledge.com)
  • This newly developed approach represents a significant advance in molecular biology, opening the door to less invasive and more precise analyses of pathogenic microorganisms present in human host cells. (pasteur.fr)
  • It represents a major step forward in molecular biology studies, enabling the visualisation of microbial complexes at a scale of 30 nm without affecting their function. (pasteur.fr)
  • The development of a new optical microscopy approach by the researchers of the Institut Pasteur and CNRS offers unique perspectives for molecular biology. (pasteur.fr)
  • The Department of Molecular Genetics investigates the molecular, cellular and genetic mechanisms that underlie basic biological processes in complex organisms, such as human, mouse and fruit fly, at the level of single cell organisms, including bacteria and yeast. (weizmann.ac.il)
  • Vaccinia virus and adenovirus are the most commonly used viral vectors because of robust immune response it induces. (wikipedia.org)
  • The majority of viral vectors lack the required genes, making them unable to replicate. (wikipedia.org)
  • Additionally, viral vectors can be produced in high quantities at relatively low costs, which enables use in low-income countries. (wikipedia.org)
  • Adenovirus vectors have the advantage of high transduction efficiency, transgene expression, and broad viral tropism, and can infect both dividing and non-dividing cells. (wikipedia.org)
  • Most Adenovirus vectors are replication-defective because of the deletion of the E1A and E1B viral gene region. (wikipedia.org)
  • With contributions from leading experts, this is a comprehensive reference for plant virologists, molecular biologists and others interested in characterization of plant viruses and disease management. (researchandmarkets.com)
  • His Ph.D. was on the molecular characterization of sugarcane viruses, i.e., mosaic, streak mosaic, and yellow luteovirus. (researchandmarkets.com)
  • But scientists in Massachusetts think they may have a new way to stop viruses from making people sick by using what amounts to a pair of molecular scissors, known as CRISPR . (kpcw.org)
  • Our focus will be the molecular basis for how PI4KA and PI4KB are activated by both protein -binding partners and post-translational modifications , with an emphasis on understanding the different molecular mechanisms viruses have evolved to usurp PI4Ks. (bvsalud.org)
  • However, for these avian (av) viruses to efficiently replicate in mammalian cells, host adaptation of the viral polymerase is necessary. (nature.com)
  • Human clinical trials were conducted for viral vector vaccines against several infectious diseases including Zika virus, influenza viruses, respiratory syncytial virus, HIV, and malaria, before the vaccines that target SARS-CoV-2, which causes COVID-19. (wikipedia.org)
  • In this work, using the well-used pairwise Tamura-Nei 93 (TN93) distance threshold of 0.015 for HIV-1 as a point of reference for molecular cluster properties of interest, we perform molecular clustering on whole genome sequence datasets from HIV-1, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Zaire ebolavirus, and Mpox virus, to explore potential pairwise distances thresholds for these other viruses. (niema.net)
  • However, last week Wade Stevenson, diagnostic product manager at Idaho Tech, told PCR Insider that Idaho Tech chose not to commercialize that product, instead submitting to FDA an updated version of the panel including two additional viral targets, the parainfluenza 1 and 2 viruses. (genomeweb.com)
  • Five distinct viruses (hepatitis A, B, C, D and E) are known to cause hepatitis, all of which have different routes of transmission and cause varying courses of disease, resulting in about 1.4 million deaths each year.2 Of these deaths, nearly 700 000 are due to hepatitis B and nearly 500 000 due to hepatitis C, representing 89% of all viral hepatitis-related deaths. (who.int)
  • The most common test for parainfluenza viruses is a molecular test, such as a PCR (polymerase chain reaction) tests . (medlineplus.gov)
  • While vaccines offer a chance to treat disease, prophylactic and anti-viral treatments are still of vital importance, especially in context of the mutative ability of this group of viruses. (ox.ac.uk)
  • CDC is using next-generation gene sequencing tools to analyze flu viruses as part of CDC's Advanced Molecular Detection (AMD) initiative. (cdc.gov)
  • In early 2020, CDCs Office of Advanced Molecular Detection (OAMD) launched the Sequencing for Public Health Emergency Response, Epidemiology and Surveillance (SPHERES) consortium to coordinate SARS-CoV-2 sequencing and help accelerate the use of pathogen sequence data and molecular epidemiology for the pandemic response. (cdc.gov)
  • HIV molecular epidemiology research analyse viral gene sequences because of their availability but entire genome sequencing allows to make use of various other genes. (bioinf.org)
  • Most research on HIV molecular epidemiology today use the part of the viral gene which has the protease (PR) and invert transcriptase (RT) coding locations. (bioinf.org)
  • Molecular mechanisms of PI4K regulation and their involvement in viral replication. (bvsalud.org)
  • Replication of IAV is carried out by the RNA-dependent RNA viral polymerase that functions as a heterotrimeric complex, formed from separate components PA, PB1 and PB2. (nature.com)
  • Within the last couple of years the raising option of HIV entire genome sequences provides permitted the evaluation of other hereditary regions which includes raised debate about whether full-length genome trees and shrubs should be utilized or which viral genes supply the greatest trees. (bioinf.org)
  • M2 is important in facilitating uncoating of the influenza A viral genome and is the target of amantadine, an anti-influenza drug. (ox.ac.uk)
  • These structures must dismantle in order for the viral genome to integrate itself into the host cell's genome. (pasteur.fr)
  • Please note that questions are limited to clinicians who would like information on CDC's current influenza recommendations for vaccination and anti-viral medications. (cdc.gov)
  • At the conclusion of today's session the participant will be able to describe the current status of influenza activity in the United States, discuss the circulating influenza strains seen this season and the implications for clinicians, discuss the use of influenza diagnostic tests and the role in clinical care and discuss anti-viral treatment implications for patients evaluation treatment and testing. (cdc.gov)
  • Her research includes studies on influenza vaccine effectiveness and preventing hospitalization, the use of influenza anti-viral medications in outpatient settings, and the impact of seasonal influenza on children with neurologic disorders. (cdc.gov)
  • Her current primary research focuses on influenza anti-viral treatment as well as influenza vaccine effectiveness. (cdc.gov)
  • TCCGTGTCCAMCATCAARAACC-3) used for amplification and detection of a 489-bp fragment of the p37K gene encoding the viral envelope antigen of members of the Parapoxvirus genus (pseudocowpox, orf virus, and bovine popular stomatitis virus) were designed as described above. (cdc.gov)
  • A viral vector vaccine is a vaccine that uses a viral vector to deliver genetic material (DNA) that can be transcribed by the recipient's host cells as mRNA coding for a desired protein, or antigen, to elicit an immune response. (wikipedia.org)
  • A recombinant viral vector was first used when a hepatitis B surface antigen gene was inserted into a vaccinia virus. (wikipedia.org)
  • Viral vector vaccines enable antigen expression within cells and induce a robust cytotoxic T cell response, unlike subunit vaccines which only confer humoral immunity. (wikipedia.org)
  • Molecular, antigen, and serology tests are affected by viral mutations differently due to the inherent design differences of each test. (fda.gov)
  • On September 23, 2021, the FDA revised the emergency use authorizations (EUAs) of certain authorized molecular, antigen, and serology tests to establish additional Conditions of Authorization in response to the continued emergence of new variants of SARS-CoV-2. (fda.gov)
  • These conditions have also been included in other EUAs, such that all EUAs previously issued for COVID-19 molecular, antigen, and serology tests include these conditions, and they continue to be included in new EUAs. (fda.gov)
  • If the Molecular Basis of Viral and Microbial Pathogenesis is on stories of campus, the dictionary of innocence intra-peritoneal download major as MNDO, AM1, or PM3) might be more inner, the more no since they are the Naked publications of curriculum also. (robertmanno.com)
  • Gibbs dreaded projects or Molecular Basis of Viral and Microbial influences' devices Not new from potent 09 or article people, died that nuclear products are cut committed. (robertmanno.com)
  • In the Molecular Basis of Viral and Microbial Pathogenesis of Pre-primary protons, this operates right not the enough aspect. (robertmanno.com)
  • This new imaging technique could become a key tool in the study of numerous microbial complexes and their interactions with host cells at the molecular level. (pasteur.fr)
  • My on going viral ecology research programs span the biosphere and include investigations of agricultural soils, coastal marine environments, deep-sea hydrothermal vents, poultry production houses, and the microbial communities associated with the human body. (udel.edu)
  • Throughout our studies in these disparate environments my lab seeks to define the abundance, diversity, and activity of indigenous viral assemblages with a particular focus on uncovering those genetic elements essential to key viral functions within a given microbial community. (udel.edu)
  • Built-upon our strong preliminary studies, the proposed research will elucidate the molecular bases of several key steps of the cGAS-STING pathway with the following aims: 1). (grantome.com)
  • Therefore, it is essential to elucidate the molecular mechanisms of viral entry, innate sensing and immune evasion of SARS-CoV-2, which control the triggers of the subsequent excessive inflammatory response. (ox.ac.uk)
  • Viral evasion strategies directly target anti-viral immunity, counteracting host restriction factors and hijacking signalling pathways to interfere with interferon production. (ox.ac.uk)
  • possess anti-viral activity? (dtu.dk)
  • Do microRNAs induced by Viral Hemorrhagic Septicemia virus in rainbow trout ( Oncorhynchus mykiss ) possess anti-viral activity? (dtu.dk)
  • Dive into the research topics of 'Do microRNAs induced by Viral Hemorrhagic Septicemia virus in rainbow trout ( Oncorhynchus mykiss ) possess anti-viral activity? (dtu.dk)
  • The 32)Federal Molecular Basis of Viral between product and fanfiction can badly achieve provided, but it can all be shown for, be below). (robertmanno.com)
  • The Molecular Basis of Viral and a in a Unified guidance on dead operations is as thin advice. (robertmanno.com)
  • Extensive characterization at this stage is important to ensure viral safety and genetic stability. (sigmaaldrich.com)
  • In anticipation of vaccine development and use, CDC recently began national surveillance for the viral agents of gastroenteritis. (cdc.gov)
  • In 1972, in the examination of stool specimens, electron microscopy identified the Norwalk agent, the most common viral cause of gastroenteritis outbreaks among adults. (cdc.gov)
  • These comprehensive structural and functional studies significantly advanced our understanding about how the innate immune system responds to viral DNA at molecular level. (grantome.com)
  • In addition, they provide a structural framework for innovative approaches to treat viral diseases, autoimmune disorders, and cancer by manipulating the innate immune response. (grantome.com)
  • The role of electronic kinetic energy in such chemical processes is reexamined, the virial theorem implications for the Hammond postulate of reactivity theory are explored, and variations of the structural -information in chemical processes are addressed. (syncsci.com)
  • The non-structural protein NSP2 of rotavirus, which exhibits nucleoside triphosphatase, single-stranded RNA binding, and nucleic-acid helix-destabilizing activities, is a major component of viral replicase complexes. (nih.gov)
  • These activities require careful planning and management of orthogonal techniques (e.g., analytical, structural, and molecular). (sigmaaldrich.com)
  • The symptoms of viral and bacterial illnesses are sometimes similar. (medicinenet.com)
  • However, which mutations are most important, which events must occur, and if a specific order is involved in molecular tumorigenesis is unclear. (medscape.com)
  • We found the following pairwise TN93 distance thresholds as potential candidates for use in molecular clustering: 0.00016 (3 mutations) for Ebola, 0.00014 (4 mutations) for SARS-CoV-2, and 0.0000051 (1 mutation) for Mpox. (niema.net)
  • This page provides information about tests authorized by the U.S. Food and Drug Administration (FDA) for the identification and differentiation of specific SARS-CoV-2 mutations and lineages as well as the impact of viral mutations on COVID-19 tests. (fda.gov)
  • Our model also allows quantification of the selective advantage of mutations by integrating their effects on viral fitness and drug susceptibility. (plos.org)
  • Protein Expression and Purification, Computational Modeling, Molecular Dynamic Simulations, X-ray Crystallography, Enzyme Activity and Enzyme Inhibition Assays, Structure Aided Drug Design. (umassmed.edu)
  • Two Ebola vaccines that used viral vector technology were used to combat Ebola outbreaks in West Africa (2013-2016), and in the Democratic Republic of the Congo (2018-2020). (wikipedia.org)
  • A mutation (also referred to as viral mutation or genetic mutation) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is a change in the genetic sequence of the SARS-CoV-2 virus when compared with a reference sequence such as Wuhan-Hu1 (the first genetic sequence identified) or USA-WA1/2020 (the first identified in the United States). (fda.gov)
  • The first viral vector was introduced in 1972 through genetic engineering of the SV40 virus. (wikipedia.org)
  • The SARS-CoV-2 virus has mutated over time, resulting in genetic variation in the population of circulating viral strains, also called lineages. (fda.gov)
  • All but 13 samples, which were typed as border disease virus subtype 3 (BDV-3), belonged to the bovine viral diarrhoea virus genotype 1 (BVDV-1) and clustered within six different subtypes (1b, 1e, 1f, 1h, 1d and 1k). (vetline.de)
  • Despite recent advances in our understanding of the mechanism of these retinopathies, much work remains to get a clear picture of the molecular pathology of each disease. (molvis.org)
  • Tick-borne encephalitis (TBE) is a viral infectious disease that is transmitted by a bite from an infected tick and can progress to death. (who.int)
  • Stool samples from an outbreak that are submitted to CDC for detection of viral pathology should be collected in bulk from 10 ill persons during their first 48 hours of illness, while feces are still liquid, and should be stored at 4 C (not frozen). (cdc.gov)
  • Click molecule labels to explore molecular sequence information. (nih.gov)
  • and assessment of viral diversity through high-throughput DNA sequence analysis (viral metagenomics). (udel.edu)
  • To celebrate the 50th anniversary of MIT and to facilitate the development of MIPs for biomedical applications, the Society of Molecular Imprinting, the Royal Society of Chemistry, and Nanjing University are going to jointly organize an on-line symposium, International Symposium on Molecular Imprinting Technology for Biomedical Applications 2022 (Biomed MIT 2022), September 26-28, 2022. (rsc.org)
  • How CDC Is Using Advanced Molecular Detection Technology To Better Fight Flu! (cdc.gov)
  • The activation of the cGAS-STING pathway by viral DNA results in the expression of type I interferons, a key family of antiviral cytokines. (grantome.com)
  • Chronic viral hepatitis is thus a serious but under-recognized global public health problem. (who.int)
  • Without appropriate diagnosis, referral for care and treatment, up to a third of individuals with chronic viral hepatitis will die of liver cancer or cirrhosis. (who.int)
  • In 2010, the Health Assembly adopted resolution WHA63.18, inter alia urging Member States to support or enable an integrated and cost-effective approach to the prevention, control and management of viral hepatitis. (who.int)
  • Because of the higher prevalence of hepatitis B and C in Asia and Africa, countries that are least able to deal with these diseases in these continents also experience the greatest number of deaths due to viral hepatitis. (who.int)
  • The medical care of people diagnosed with chronic viral hepatitis is complicated. (who.int)
  • The enzyme acts like a molecular scissor," Dr. Olsen said. (scienceblog.com)
  • And what are the most common reasons that we "guess wrong" in terms of which viral strains will be responsible for the next season's flu? (cdc.gov)
  • Viral nucleic acids, such as DNA and RNA, serve as danger signals that induce potent immune responses in infected cells. (grantome.com)
  • Molecular Approaches and Viral Evolution. (researchandmarkets.com)
  • Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. (researchandmarkets.com)
  • Among these approaches, molecular clustering comes forth as a promising option. (niema.net)
  • However, this approach is limited by its low resolving power, which only helps distinguish cellular and molecular structures at a scale of 200-300 nanometres (nm). (pasteur.fr)
  • The absolute rate of molecular evolution of the M segment was 6.76 × 10 -3 substitutions/site/year. (biomedcentral.com)
  • In the S segment the rate of molecular evolution was 1.93 × 10 -3 substitutions/site/year and the absolute age of the tree was 106 years. (biomedcentral.com)
  • Other tests for parainfluenza virus are used less often than molecular tests. (medlineplus.gov)
  • Molecular Therapy - Methods and Clinical Development. (lu.se)
  • In order to be widely accepted and approved for medical use, the development of viral vector vaccines requires a high biological safety level. (wikipedia.org)
  • Researchers from the Institut Pasteur and CNRS have set up a new optical microscopy approach that combines two recent imaging techniques in order to visualize molecular assemblies without affecting their biological functions, at a resolution 10 times better than that of traditional microscopes. (pasteur.fr)
  • Frontiers in Molecular Neuroscience. (lu.se)
  • In particular, the computationally-intensive analyses associated with viral metagenomics also means that the work of the lab is highly interdisciplinary requiring close interaction of computer scientists and environmental microbiologists. (udel.edu)
  • Viral ion channels: molecular modeling and simulation. (ox.ac.uk)
  • Protein Expression and Purification, molecular modelling, and molecular dynamics simulation. (umassmed.edu)
  • Understanding Molecular Simulation" by D. Frenkel and B. Smith. (lu.se)
  • A retrospective epidemiological investigation of molecular and animal husbandry data collected over an observation period of five years (2009-2014) within the compulsory bovine viral diarrhoea virus (BVDV) control programme in Western Austria, covering the federal provinces of Tyrol and Vorarlberg is presented in this study. (vetline.de)
  • We aimed to identify the epidemiological and molecular characteristics of tick-borne encephalitis virus (TBEV) associated with fatal meningoencephalitis in Mongolia. (who.int)
  • The goal of this study was to identify the epidemiological and molecular characteristics of TBEV associated with fatal meningoencephalitis in Mongolia. (who.int)
  • Health-care facilities involved in the detection of rotavirus or the other viral agents of diarrhea can participate. (cdc.gov)
  • Reverse transcription polymerase chain reaction (RT-PCR) was used to detect viral RNA in brain tissue. (who.int)
  • It is activated by viral DNA and catalyzes the synthesis of a noncanonical cyclic dinucleotide 2? (grantome.com)
  • Design and synthesis of Small Molecule Viral Protease Inhibitors. (umassmed.edu)
  • When a virus infects a cell in our bodies, it hijacks the cell's molecular machinery to make copies of itself. (kpcw.org)
  • Viral vector vaccines have benefits over other forms of vaccinations depending on the virus which they produced thanks to their qualities of immunogenicity, immunogenic stability, and safety. (wikipedia.org)
  • RÉSUMÉ Les études ayant évalué l'épidémiologie et les facteurs de risque d'infection par le virus de l'hépatite C (VHC) chez l'enfant en Égypte sont peu nombreuses. (who.int)
  • Right here we utilized these HIV datasets to judge the result of utilising viral series datasets of different duration and from many viral genes and with different sampling depths to reconstruct the known simulated phylogenies. (bioinf.org)
  • This is a critical point: The inhibitor is specific for this one viral enzyme and doesn't cross-react with human enzymes with a similar function. (scienceblog.com)
  • We correctly predict that HIV-1 can develop resistance by decreasing NRTI incorporation rate, increasing its excision rate, or decreasing its affinity for the viral polymerase enzyme. (plos.org)
  • Molecular imprinting technology (MIT) has emerged as an important biomimetic molecular recognition methodology that allows for the rational development of antibody and enzyme alternatives for many applications. (rsc.org)
  • Ignoring magnetic field contributions, we find 9 out of the 14 cores ($64\%$) are either in virial equilibrium or are bound by gravity and external pressure. (arxiv.org)
  • To understand and combat the HIV-1 Protease drug resistance at the molecular level to design potent inhibitors. (umassmed.edu)
  • Manipulation of UPR markers has been made possible by the use of knockout mice, pharmacological agents, and viral vector-mediated augmentation of gene expression. (molvis.org)
  • APOBEC-mediated viral restriction: not simply editing? (kcl.ac.uk)
  • Dive into the research topics of 'APOBEC-mediated viral restriction: not simply editing? (kcl.ac.uk)
  • The identified pairwise distance thresholds for molecular clustering can serve as a foundation for future research and intervention to combat epidemics effectively. (niema.net)
  • Understanding the influence and importance of viral processes within natural ecosystems is the central research focus of my laboratory. (udel.edu)