Microbiology and ImmunologyInfectionInfectionsFrontiersInfectious diseasesHepatitis2020VaccinesVaccineInflammationImmunityDistinguished Professor of MicrobiologyMolecular BiologyMechanismsAnti-viralAntibodiesDiseasesAntiviralEvasionPathogensReplicationResponsesPneumoniaPreventionEpidemiologyProteinHttpsGenesAllergy
Microbiology and Immunology3
- Your submission to Microbiology and Immunology Emphasis has been sent. (petersons.com)
- Microbiology and Immunology Emphasis / Microbiology and Immunology Emphasis is located in Nashville, TN. (petersons.com)
- Dr. Massung received his PhD from the Department of Medical Microbiology and Immunology, College of Medicine, University of Florida, Gainesville, FL. (cdc.gov)
Infection9
- Nature Immunology has commissioned a Focus series of Reviews and Perspectives that discuss the innate and adaptive aspects of the immune response to SARS-CoV2, the possible mechanisms behind the large clinical variability in the response to infection, and considerations for vaccine and therapy strategies. (nature.com)
- Viral vector vaccines do not cause infection with either the virus used as the vector or the source of the antigen. (wikipedia.org)
- We discuss the different vectored vaccines that have been or are currently in clinical trials, with a forward-looking focus on immunogens that may be protective against seasonal and pandemic influenza infection, in the context of viral-vectored vaccines. (mdpi.com)
- We then explored the realm of possible dynamics for scenarios not examined experimentally, including different infection order, coinfection timing, interaction mechanisms, and viral pairings. (biorxiv.org)
- In case of post coronavirus disease 2019 infection or vaccination, viral specific T SCM cells are generated that provide long term protective immunity. (wjgnet.com)
- Cytomegalovirus infection (a viral infection that can affect almost any organ system, especially the eyes. (i-sis.org.uk)
- Our research aims at answering the following questions: Which mechanisms and specific patterns lead to the recognition of a viral infection? (uni-bonn.de)
- et 20 témoins en bonne santé ne présentant pas d'infection par le virus de l'hépatite C. Une réduction importante de la fréquence des cellules tueuses naturelles totales dans le groupe des patients porteurs d'une infection chronique a été observée par rapport au groupe des témoins ( P = 0,001) ou au groupe des patients dont l'infection a connu une résolution spontanée ( P = 0,01). (who.int)
- 23.Liu H, Wang L-L, Zhao S-J, Kwak-Kim J, Mor G, Liao A-H. Why are pregnant women susceptible to viral infection: an immunological viewpoint? (bvsalud.org)
Infections13
- Viral infections are responsible for many human diseases, from common diseases like the flu to emerging infections such as Zika virus and SARS-CoV-2. (masslifesciences.com)
- Understanding how the immune system works to prevent and remove viral infections is essential for anyone working to develop or distribute vaccines that can protect against these diseases. (masslifesciences.com)
- This advanced course offers a unique way for professionals to learn from leading Harvard Medical School faculty about cutting-edge developments in the creation of vaccines to protect against viral infections. (masslifesciences.com)
- Further, re-emerging viruses have the tendency to mutate and infect unnatural hosts, leading to the emergence of new viral infections with the capacity to infect humans, animals, and other mammals, and eventually leading to pandemic conditions in the future similar to COVID-19. (mdpi.com)
- In the phase of preparation for future pandemics, it is necessary for the research community to study in detail the changes in mechanisms underlying virus mutation, virus-host interaction, viral immunology, possible treatment, and potent vaccine candidates for viral infections post-COVID-19. (mdpi.com)
- The RV144 HIV-1 vaccine trial results showed moderate reduction in viral infections among vaccinees as well as induction of antibody-dependent cellular cytotoxicity and vaccine-specific IgG and IgG3 responses directed at variable loop regions 1 and 2 of the HIV envelope protein. (nih.gov)
- Some infections with viral copathogens have been shown to result in reduced pathogenicity while other virus pairings can worsen disease. (biorxiv.org)
- IAV coinfection with rhinovirus (RV) or SARS-CoV-2 (CoV2) was examined by using human viral load data from single infections together with murine weight loss data from IAV-RV, RV-IAV, and IAV-CoV2 coinfections to guide the interpretation of the model results. (biorxiv.org)
- Project grant recipients are leaders in their fields and their projects tackle pressing health issues that matter to Canadians, such as chronic pain management, mental health literacy intervention for Indigenous youth, and harnessing mast cell responses to viral infections. (dal.ca)
- Sachdeva M, Taneja S, Sachdeva N. Stem cell-like memory T cells: Role in viral infections and autoimmunity. (wjgnet.com)
- In which cells are viral infections actually recognized - the non-infected, or the infected ones? (uni-bonn.de)
- Antibiotics help with bacterial infections, not with viral infections such as colds. (medlineplus.gov)
- Unexpectedly, 8-oxoguanine DNA glycosylase1 (Ogg1) knockout mice show enhanced stimuli-driven IFN expression that confers increased resistance to viral and bacterial infections and allergen challenges. (lu.se)
Frontiers1
- Jianxun Song , " Frontiers in Cancer Immunology ", Bentham Science Publishers (2015). (benthamscience.com)
Infectious diseases5
- Human clinical trials were conducted for viral vector vaccines against several infectious diseases including Zika virus, influenza viruses, respiratory syncytial virus, HIV, and malaria, before the vaccines that target SARS-CoV-2, which causes COVID-19. (wikipedia.org)
- This Special Issue on "Emerging Viral Infectious Diseases: Immunology, Therapeutics and Prevention during a Post-Pandemic Era" is mainly focused on the study of the immunology, viral-host interaction, and immunotherapy of (re-)emerging viral infectious diseases in humans, animals, and mammals. (mdpi.com)
- ITMO I3M resulted from the linking of the themes "Microbiology and infectious diseases" and "Immunology and inflammation. (aviesan.fr)
- WHO Collaborating Center for Influenza, Influenza Br and Epidemiology Office, Div of Viral Diseases, Center for Infectious Diseases, CDC. (cdc.gov)
- Serum samples were processed, stored, and shipped to the Chronic Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA for analysis. (cdc.gov)
Hepatitis2
- A recombinant viral vector was first used when a hepatitis B surface antigen gene was inserted into a vaccinia virus. (wikipedia.org)
- Most cases of acute viral hepatitis. (msdmanuals.com)
20202
- The paper is selected as a BEST OF TRENDS IN IMMUNOLOGY 2020 . (sjleelab.com)
- Two Ebola vaccines that used viral vector technology were used to combat Ebola outbreaks in West Africa (2013-2016), and in the Democratic Republic of the Congo (2018-2020). (wikipedia.org)
Vaccines7
- As of April 2021[update], six viral vector vaccines, four COVID-19 vaccines and two Ebola vaccines, have been authorized for use in humans. (wikipedia.org)
- Viral vector vaccines enable antigen expression within cells and induce a robust cytotoxic T cell response, unlike subunit vaccines which only confer humoral immunity. (wikipedia.org)
- In order to be widely accepted and approved for medical use, the development of viral vector vaccines requires a high biological safety level. (wikipedia.org)
- Viral vector vaccines have benefits over other forms of vaccinations depending on the virus which they produced thanks to their qualities of immunogenicity, immunogenic stability, and safety. (wikipedia.org)
- While vaccines offer a chance to treat disease, prophylactic and anti-viral treatments are still of vital importance, especially in context of the mutative ability of this group of viruses. (ox.ac.uk)
- There are a number of alternate vaccination strategies in current development which may circumvent the need for annual re-vaccination, including new platform technologies such as viral-vectored vaccines. (mdpi.com)
- Immunology is undeniably a pivotal part of medicine, and a source of prophylactic solutions (vaccines) and therapeutic agents in many medical disciplines. (aviesan.fr)
Vaccine3
- A viral vector vaccine is a vaccine that uses a viral vector to deliver genetic material (DNA) that can be transcribed by the recipient's host cells as mRNA coding for a desired protein, or antigen, to elicit an immune response. (wikipedia.org)
- The companion vaccine trial RV305 was designed to permit the evaluation of the immunologic impact of late boosting with either the boosting protein antigen alone, the canarypox viral vector ALVAC alone, or a combination of both. (nih.gov)
- Unfortunately, influenza vaccine composition needs to be updated annually due to antigenic shift and drift in the viral immunogen hemagglutinin (HA). (mdpi.com)
Inflammation1
- Since January 2015, ITMO I3M has been coordinating research in areas of Immunology, Inflammation, Infectious disease and Microbiology (I3M). (aviesan.fr)
Immunity3
- Counteracting innate immunity is essential for successful viral replication. (nih.gov)
- Collectively, our study identifies a novel antiviral mechanism that harnesses cellular antiviral immunity to suppress viral replication. (nih.gov)
- Viral evasion strategies directly target anti-viral immunity, counteracting host restriction factors and hijacking signalling pathways to interfere with interferon production. (ox.ac.uk)
Distinguished Professor of Microbiology1
- Congratulations to Blossom Damania, who has just been named the Cary C. Boshamer Distinguished Professor of Microbiology & Immunology. (unc.edu)
Molecular Biology1
Mechanisms5
- Host cyclophilins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechanisms are still unclear. (nih.gov)
- Therefore, it is essential to elucidate the molecular mechanisms of viral entry, innate sensing and immune evasion of SARS-CoV-2, which control the triggers of the subsequent excessive inflammatory response. (ox.ac.uk)
- In Part I of this review, we examine SARS-CoV-2 viral entry and the described immune evasion mechanisms to provide a perspective on how the failure in initial viral sensing by infected cells can lead to immune dysregulation causing fatal COVID-19, discussed in Part II. (ox.ac.uk)
- To better understand viral-viral coinfections and predict potential mechanisms that result in distinct disease outcomes, we first systematically fit mathematical models to viral load data from ferrets infected with respiratory syncytial virus (RSV) followed by influenza A virus (IAV) after 3 days. (biorxiv.org)
- Early virus-host interactions are an interplay of viral exploitation of cellular proteins, functions, and innate defence mechanisms. (uni-bonn.de)
Anti-viral4
- possess anti-viral activity? (dtu.dk)
- Do microRNAs induced by Viral Hemorrhagic Septicemia virus in rainbow trout ( Oncorhynchus mykiss ) possess anti-viral activity? (dtu.dk)
- Dive into the research topics of 'Do microRNAs induced by Viral Hemorrhagic Septicemia virus in rainbow trout ( Oncorhynchus mykiss ) possess anti-viral activity? (dtu.dk)
- Do anti-viral drugs really help? (i-sis.org.uk)
Antibodies2
- Enhancement of viral infectivity caused by non-neutralizing antibodies. (bvsalud.org)
- Title : Guidelines for plaque-reduction neutralization testing of human antibodies to dengue viruses Corporate Authors(s) : National Center for Zoonotic, Vector-Borne and Enteric Diseases (U.S.) Published Date : June 2008 Source : Viral immunology. (cdc.gov)
Diseases4
- During this period, the study of existing/emerging viral diseases was given a lower priority. (mdpi.com)
- The pandemic has changed the disease incidence, immune responses, and mortality rates of various epidemic and endemic viral diseases, such as influenza virus, RSV, etc. (mdpi.com)
- Dr. Robert Massung, PhD., serves as Chief of the Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector-Borne, and Enteric Diseases. (cdc.gov)
- Viral and immunological diseases in nonhuman primates : proceedings of a Symposium, Use of Nonhuman Primates in Exotic Viral and Immunological Disease, held February 28-March 3, 1982, in San Antonio, Texas / editor, S. S. Kalter. (who.int)
Antiviral2
- antiviral compounds, systems biology of viral hemorrhagic fever, novel approaches to virus detection. (bu.edu)
- Pharmacological inhibition of CypA rescues PKR from antagonism by HCV NS5A, leading to activation of an interferon regulatory factor-1 (IRF1)-driven cell intrinsic antiviral program that inhibits viral replication. (nih.gov)
Evasion1
- Part I: viral entry, sensing and evasion. (ox.ac.uk)
Pathogens2
- Viral pneumonia occurs due to aggression of the viral pathogens on the lung structures. (medscape.com)
- Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ. (upenn.edu)
Replication2
- Most Adenovirus vectors are replication-defective because of the deletion of the E1A and E1B viral gene region. (wikipedia.org)
- Ongoing viral replication results in major viremia that spreads the virus to targets such as the CNS. (medscape.com)
Responses1
- Most functional responses increased upon protein boosting, regardless of the viral vector-priming agent incorporation. (nih.gov)
Pneumonia4
- Because of the clinical manifestations and the radiologic aspects, viral pneumonia was included in the broad category of atypical pneumonias. (medscape.com)
- In this category, viral pneumonia and the other atypical bacterial pneumonias must be differentiated. (medscape.com)
- Viral pneumonia can have different manifestations. (medscape.com)
- DNA and RNA viruses are involved in the etiology of viral pneumonia. (medscape.com)
Prevention1
- The M9ELISA was conducted in HPV Immunology lab at the Centers for Disease Control and Prevention. (cdc.gov)
Epidemiology1
- Wastewater-based epidemiology (WBE), which uses nucleic acid amplification tests to detect viral fragments, is a faithful proxy of COVID-19 incidence and prevalence, and thus offers the potential to monitor VOC viral load in a given population. (medrxiv.org)
Protein1
- 1 , 2 , 3 The viral envelope of coronaviruses is composed of four major viral structural protein components: spike (S) protein, membrane (M) protein, nucleocapsid (N), and the envelope (E) protein. (ispe.org)
Https1
- https://www.amed.go.jp/en/news/release_20191026.html 2. (sjleelab.com)
Genes2
- The majority of viral vectors lack the required genes, making them unable to replicate. (wikipedia.org)
- He was tipped as a Nobel candidate for his work on viral oncogenes (genes causing cancer). (i-sis.org.uk)
Allergy1
- Results of search for 'ccl=su:{Allergy and immunology. (who.int)