Viral host. Medical search. Frequent questions

RNA splicing plays important roles in viral replication and virus-host interactions 38 . (nature.com)
Although the main pathway controlled by activation of the IKKβ kinase (called the NF-κB signaling pathway) is normally detrimental to viral replication, MHV68 co-opts IKKβ kinase activation to boost its own viral transcription activator, using a viral protein called RTA, thereby enhancing viral gene expression and virus production. (medicalxpress.com)
Fatal infectious diseases caused by HIV-1, influenza A virus, Ebola virus, and currently pandemic coronavirus highlight the great need for the discovery of antiviral agents in mechanisms different from current viral replication-targeted approaches. (physiciansweekly.com)
The transient increase in variation observed in the new host species may represent virus replication within a new environment, perhaps due to increased replication within the CNS, resulting in a larger population of viruses, or due to the lack of host constraints present in the new host reservoir. (gla.ac.uk)
During viral replication in a host, the negative sense single stranded RNA genome of IAV accumulates genetic diversity that may have important consequences for viral evolution and transmission . (bvsalud.org)
Viruses have optimized their evading tactics for superior replication and spreading to counteract host immunity. (frontiersin.org)
Altogether, our data provide new insight into the central role of ACBD3 in recruiting PI4KB by enterovirus 3A and reveal the minimal domains of ACBD3 involved in recruiting PI4KB and supporting enterovirus replication.IMPORTANCE Similar to all other positive-strand RNA viruses, enteroviruses reorganize host cellular membranes for efficient genome replication. (uu.nl)
Viral replication is nuclear. (wikipedia.org)
In HHV-1 and HHV-2 oral infections, viral replication within the oral epithelium may cause lysis of epithelial cells, with vesicle formation. (medscape.com)
This enzyme is essential for conversion of the viral RNA to proviral DNA, which integrates in the host DNA and results in viral replication. (who.int)
Sub-optimal adherence may reduce the effectiveness of the regimen by allowing viral replication and the emergence of drug resistant strains. (who.int)

Study the role of HIV-1 sequence diversity in understanding neurovirulence, neurotropism, discordant and compartmentalized viral evolution, CNS cell type-specific infection, regional genetic heterogeneity, and associated functional effects. (nih.gov)
Assess epigenetic host response to viral infection mediated through chromatin modification, non-coding RNAs, and DNA methylation. (nih.gov)
A key issue in current HTLV-I research is to better understand the dynamic interaction between persistent infection by HTLV-I and virus-specific host immunity. (ebi.ac.uk)
Examining the particular roles of viral expression and host immunity during the chronic phase of HTLV-I infection offers important insights regarding the evolution of viral persistence and proposes a hypothesis for pathogenesis. (ebi.ac.uk)
SINEs are normally silent, though in some cases viral infection can promote their transcription into RNA. (medicalxpress.com)
Britt Glaunsinger and her colleagues from the University of California in Berkeley, are interested in potential roles for SINE RNA transcripts during viral infection . (medicalxpress.com)
This activation of SINE expression is a biphasic response, with an initial phase arising as a result of either viral attachment or entry in to cells, and a second wave that requires progression of the infection past entry and expression of immediate early and early viral genes. (medicalxpress.com)
Collectively", the researchers conclude, "we reveal the first example of a role for SINE RNAs in the host-pathogen interaction and identify them as key immune signaling molecules early during infection. (medicalxpress.com)
More importantly, these target genes were enriched for cellular processes that facilitated the viral infection. (biomedcentral.com)
They have co-evolved with their host over millions of years and have had to adapt to the cellular environment, which in turn is evolving to evade viral infection. (biomedcentral.com)
Because studies from our laboratory have demonstrated that chitinase 3-like-1 (CHI3L1) stimulates ACE2 and Spike (S) priming proteases that mediate SC2 infection, studies were undertaken to determine if interventions that target CHI3L1 are effective inhibitors of SC2 viral variant infection. (elifesciences.org)
Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infection in infants and children and the second most common viral cause of pneumonia in adults. (medscape.com)
Control measures for outbreaks of viral gastroenteritis should focus on the removal of an ongoing common source of infection (e.g., an ill food handler or the contamination of a water supply) and on the interruption of person-to-person transmission that can perpetuate an outbreak in a population after the common source has been removed. (cdc.gov)
Host risk factors , including compromised immunity and pre-existing health conditions, can contribute to increased infection susceptibility and disease severity . (bvsalud.org)
Using a co-caging study design, we investigated the maintenance , generation, and transmission of intrahost IAV genetic variation by sequencing viral genomic RNA obtained from nasal wash samples over multiple days of infection . (bvsalud.org)
Here we outline the current status of the viral evasion mechanism underlying the regulation of the cGAS-STING pathway, focusing on how post-transcriptional modifications, viral proteins, and non-coding RNAs involve innate immunity during viral infection, attempting to inspire new targets discovery and uncover potential clinical antiviral treatments. (frontiersin.org)
Ligand-coated viruses stimulate type I IFN signaling, activate TAM receptors on dendritic cells (DCs), and suppress type II interferon signaling to circumvent host defenses and advance infection.TAM-deficient DCs exhibit type I IFN responses that are more pronounced than those of wild-type cells in response to viral exposure. (wikipedia.org)
Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. (mdpi.com)
What Is a Viral Infection? (medicinenet.com)
A viral infection is a proliferation of a harmful virus inside your body. (medicinenet.com)
With an active viral infection, a virus makes copies of itself and bursts the host cell (killing it) to set the newly-formed virus particles free. (medicinenet.com)
Is it a Bacterial or Viral Infection? (medicinenet.com)
Contaminated food and water are other potential sources of viral infection. (medicinenet.com)
Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead to cirrhosis, cancer, and liver failure. (wjgnet.com)
[ 5 , 6 ] In a localized primary infection, the virus penetrates the mucosal epithelium and invades the cells of the basal layer, where the viral DNA inserts into the host DNA. (medscape.com)
The viral S gene is important as it codes for the Spike protein which is the molecule that makes contact with, and allows entry of the virus into susceptible host cells, causing infection. (who.int)
To date, WHO has designated 4 SARS CoV-2 genotypes that meet the working definition of a VOC: i) contain mutations divergent from the Wuhan strain and ii) that the mutations impact one or more of the aspects of viral infection that have public health significance. (who.int)
OBJECTIVE: Untreated perinatal HIV-1 infection is often associated with rapid disease progression in children with HIV (CWH), characterized by high viral loads and early mortality. (lu.se)

After a social media post of an entire dumpster full of books went viral, the Weird Space will be hosting a free book giveaway Friday. (kcbd.com)
On Tuesday, the City of Philippi announced that Sam Eplin, whose song "Songbird" recently went viral, will be one of the one of the performers. (wboy.com)
The McCamey team had earned five batter interference calls - which resulted in outs - prior to the Cisco incidents that went viral on social media, Woodard said. (kxnet.com)
Woodard, however, maintained that he did not condone the behavior, claiming the footage that went viral is "not how he remembers" the incident occurring. (kxnet.com)
Trevor's tweet about the cheese sandwiches went viral, and now he's auctioning the tweet off as an NFT, a non-fungible token. (wyso.org)

Understand the role of viral and host transcriptional regulation (including viral protein modifications, histone modifications, changes in chromatin structure, and non-coding RNA) in HIV-1 neuropathogenesis. (nih.gov)
It has been well demonstrated that viruses deploy host AS machinery for viral protein productions. (nature.com)
To mediate viral entry, the S protein is processed into S1 and S2 subunits by the S priming proteases (SPP), including TMPRSS2, cathepsin L (CTSL), and, to a lesser degree, FURIN. (elifesciences.org)
A viral envelope protein or E protein is a protein in the envelope, which may be acquired by the capsid from an infected host cell. (wikipedia.org)
The membrane fusion event that triggers viral entrance is caused by the viral fusion protein. (wikipedia.org)
To create potentially protective vaccines for human pathogenic enveloped viruses for which there is currently no vaccine, it is essential to comprehend how antibodies interact with viral envelope proteins, particularly with the fusion protein, and how antibodies neutralize viruses. (wikipedia.org)
Priming by proteolytic processing, either of the fusion protein or of a companion protein, is necessary for the majority of viral fusion proteins. (wikipedia.org)
This protein is a critical in the linking of the virus to a host cell it can infect. (who.int)

Airbnb cases continue to fascinate social media users, and it comes after an annoyed host shared footage of a guest covering a doorbell camera - managing to divide TikTok . (indy100.com)
Welcome back to Chronically Online, where we break down the latest memes, TikTok trends, and viral moments that are buzzing around in your phone. (yahoo.com)
Sign up for the newsletter here to be the first to see the internet's hottest topics, from the Twitter main character of the week to viral TikTok sounds to an explainer on what "IJBOL" means. (yahoo.com)
A woman on TikTok has gone viral after she posted a video of herself riding transit with a bag of lemon juice to curb motion sickness. (yahoo.com)
On Sept. 23, 22-year-old Darcy McQueeny ( @darcymcqueenyyy ) took to TikTok to share a video of herself holding a resealable bag of lemon juice to her nose, while en route to the Jonas Brothers concert. (yahoo.com)
The post Doctor weighs in on viral TikTok video of a woman smelling lemon juice to curb motion sickness appeared first on In The Know . (yahoo.com)

This is a four-dimensional, non-linear system of ordinary differential equations that describes the dynamic interactions among viral expression, infected target cell activation, and the HTLV-I-specific CTL response. (ebi.ac.uk)
The focus of this initiative is to encourage studies to discover novel genetic paradigms that may account for the interactions between the virus, the host, and the therapeutic drugs in the central nervous system (CNS) that result in the pathogenesis, progression, and clinical manifestations of HAND. (nih.gov)
This new edition introduces new, emerging proteins involved in host-virus interactions and provides in-depth coverage of plant virus genes' interactions with host, localization and expression. (researchandmarkets.com)
Figure 1 depicts all possible miRNA-mediated interactions between a virus and the host. (biomedcentral.com)
The researchers observed an increased etiological importance of HPV35, particularly the A2 sublineage of HPV35, among women of African ancestry in a large international epidemiological and viral genetic study, bolstered by genetic evidence for host-viral genotype-genotype interactions in Africa. (who.int)

For instance, due to their genetic flexibility, viruses have developed various viral proteins and non-coding RNAs to interrupt several checkpoints of cGAS-STING. (frontiersin.org)
The models of most immune evasion during innate immune responses are conserved, including altering the post-transcriptional modifications (PTMs) of vital proteins to inactivate or degrade these components, eluding DNA sensing from PRRs, decreasing cyclic GMP-AMP (cGAMP) cellular abundance, and modifying metabolism approach in host cells ( Eaglesham and Kranzusch, 2020 ). (frontiersin.org)
This happens in the case of enveloped viruses when the antibodies bind to the viral envelope proteins. (wikipedia.org)
So far, structural studies have revealed two kinds of viral fusion proteins. (wikipedia.org)
The envelopes are typically derived from portions of the host cell membranes (phospholipids and proteins), but include some viral glycoproteins. (wikipedia.org)
Viral glycoproteins, a new class of cellular inhibitory proteins has been discovered. (wikipedia.org)
Being made up mostly of host membrane, the viral envelope can also have the proteins associated with the host cell within their membrane after budding. (wikipedia.org)
During this procedure, viral transmembrane proteins, also known as spike proteins, are integrated into membrane vesicles containing components of the viral core (capsid). (wikipedia.org)
For a very long time, it was thought that the spike proteins, which are necessary for infectivity, were directly incorporated into the viral core through their cytoplasmic domains. (wikipedia.org)
These viruses can form bud particles even in the absence of spike proteins by relying only on viral core components. (wikipedia.org)
The spike proteins can occasionally be produced as virus-like particles without the viral core. (wikipedia.org)
ACBD3 is responsible for proper localization of enteroviral 3A proteins in host cells, which is important for 3A to recruit PI4KB. (uu.nl)

See Cutaneous Manifestations of HIV Disease and Cutaneous Manifestations of Hepatitis C for information on these viral infections. (medscape.com)
The process of developing the draft global health sector strategy on sexually transmitted infections was managed together with the draft global health sector strategies on HIV and on viral hepatitis. (who.int)

The program encourages use of state-of-the-art approaches (e.g., transcriptomics, phenomics, epigenomics, whole genome association studies, next generation sequencing, single cell technologies, and systems biology) to identify and validate viral and host genetic factors that influence the pathophysiology of HIV-1 associated CNS dysfunction. (nih.gov)
Detailed analysis of the splicing junctions showed clusters of AS events occurred in two regions of the virus genome, demonstrating that transcriptome analysis could gain valuable insights into viral splicing. (nature.com)
The use of state-of-the-art genetic approaches (including transcriptomics, phenomics, epigenomics, whole genome association studies, next generation sequ encing, exome sequencing, & systems biology) to identify and validate (including in vitro models, animal models, & human samples) viral and host genetic factors which influence the pathophysiology of HAND are encouraged. (nih.gov)
In addition, we identified numerous cases of recurrent low-frequency mutations throughout the genome that were specific to obese hosts. (bvsalud.org)

However, knowledge on viral AS is limited to a few disease-causing viruses in model species. (nature.com)
Molecular evolutionary analyses can trace viral origins by establishing relatedness and divergence times of viruses and identifying past selective pressures. (nih.gov)
Plants and invertebrates employ their miRNA in defense against viruses by targeting and degrading viral products. (biomedcentral.com)
Viruses also encode miRNAs and there is evidence to suggest that virus-encoded miRNAs target specific host genes and pathways that may be beneficial for their infectivity and/or proliferation. (biomedcentral.com)
Here we show that for several of the 135 known viral miRNAs in human viruses, the human genes targeted by the viral miRNA are enriched for specific host pathways whose targeting is likely beneficial to the virus. (biomedcentral.com)
Given that viral miRNAs continue to be discovered as technologies evolve, we extended the investigation to 6809 putative miRNAs encoded by 23 human viruses. (biomedcentral.com)
Overall, our results suggest that viruses may have evolved their miRNA repertoire to target specific host pathways as a means for their survival. (biomedcentral.com)
There are known instances of viruses using their endogenous miRNAs to target their own genes to evade host immune system's surveillance and maintain latency (Figure 1c ) [ 8 ]. (biomedcentral.com)
DNA viruses have utilized several mechanisms to evade host defenses [ 11 ]. (biomedcentral.com)
These properties of triterpenoids supply their host an evolutionary advantage for chemical defense and may protect against an increasingly diverse array of viruses infecting mammals, providing a direction for antiviral drug discovery. (physiciansweekly.com)
viruses from the early period after the host shift exhibited greater sequence variation in comparison to those from the later stage, and to those not involved in the host shift event, possibly indicating a role in establishing transmission within a new host. (gla.ac.uk)
The influenza viruses are the most common viral cause of pneumonia. (medscape.com)
A viral envelope is the outermost layer of many types of viruses. (wikipedia.org)
Numerous human pathogenic viruses in circulation are encased in lipid bilayers, and they infect their target cells by causing the viral envelope and cell membrane to fuse. (wikipedia.org)
They may help viruses avoid the host immune system. (wikipedia.org)
Over the course of two days, we will engage with ideas about symbiotic and therapeutic viruses, as well as viral processes that disrupt debates about Life and Nonlife. (e-flux.com)
Viruses depend on the organisms they infect (hosts) for their very survival. (medicinenet.com)
For example, some viruses protect the host against other infections. (medicinenet.com)
Viruses cannot reproduce without the assistance of a host. (medicinenet.com)
Viruses infect a host by introducing their genetic material into the cells and hijacking the cell's internal machinery to make more virus particles. (medicinenet.com)
Viruses are much smaller than bacteria and can't reproduce without the assistance of a host. (medicinenet.com)
Bacteriophages (phages), viruses that infect and replicate within bacteria, are important in both natural and human microbiomes because they prey on bacterial hosts, mediate horizontal gene transfer, alter host metabolism and redistribute bacterially derived compounds via host cell lysis 1 . (nature.com)

Unfortunately, diagnostic technology is insufficiently developed to permit determining the disease burden of each of the known viral pathogens. (cdc.gov)

In 1972, in the examination of stool specimens, electron microscopy identified the Norwalk agent, the most common viral cause of gastroenteritis outbreaks among adults. (cdc.gov)

c) Virus encoded miRNAs target viral genes to mediate immune evasion or maintenance of latency. (biomedcentral.com)

The symptoms of viral and bacterial illnesses are sometimes similar. (medicinenet.com)

Molecular Approaches and Viral Evolution. (researchandmarkets.com)
Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. (researchandmarkets.com)

Extreme genomic CpG deficiency in SARS-CoV-2 and evasion of host antiviral defense. (nih.gov)

Their efficacy in patients with influenza viral pneumonia or severe influenza is unknown. (medscape.com)
Host obesity impacts genetic variation in influenza A viral populations. (bvsalud.org)
Influenza is an infectious viral illness. (cdc.gov)

As with single nucleotide variants, we identified a class of defective viral genomes (DVGs) that were found uniquely in either obese or lean hosts, but overall DVG diversity and dynamics did not differ between the two groups. (bvsalud.org)
One of the proposed modes of action of RBV is a direct mutagenic effect on viral genomes, inducing mismatches and subsequent nucleotide substitutions. (mdpi.com)
The recently reported phage genomes range up to 735 kb in length and encode a diversity of genes involved in transcription and translation, as well as genes that may augment host metabolism 2 . (nature.com)

We investigate the role of a constantly changing anti-viral immune environment acting in response to the effects of infected T-cell activation and subsequent viral expression. (ebi.ac.uk)

They're also $150, but the fact that they've gone viral is probably why they sold out. (yahoo.com)
In a video that has gone viral since Fealy posted it on social media Labor Day weekend, she begins screaming and jumping up and down when she realizes she is being proposed to. (wvnstv.com)

Plant Virus-Host Interaction. (researchandmarkets.com)
Triterpenoid-Mediated Inhibition of Virus-Host Interaction: Is Now the Time for Discovering Viral Entry/Release Inhibitors from Nature? (physiciansweekly.com)

The researchers show that the resulting host-derived SINE RNAs are robust activators of a key signaling molecule in the non-specific (or innate) immune response called the IKKβ kinase. (medicalxpress.com)
Though SINE RNAs activate the innate immune response , MHV68 has co-opted SINE-mediated innate immune activation to enhance the viral lifecycle. (medicalxpress.com)

We found evidence for an enhanced role of positive selection acting on de novo mutations in obese hosts that led to nonsynonymous changes that rose to high frequency. (bvsalud.org)
Major drawbacks of this therapy are that RBV is not approved for administration to pregnant women and that the virus can acquire mutations, which render the intra-host population less sensitive or even resistant to RBV. (mdpi.com)

How Long Are Viral Infections Contagious? (medicinenet.com)
Viral infections are contagious for varying periods of time depending on the virus. (medicinenet.com)
Respiratory viral infections affect the lungs, nose, and throat. (medicinenet.com)
Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. (medscape.com)
Nonetheless, many other viral infections can affect the oral cavity in humans, either as localized or systemic infections. (medscape.com)
Herpesviruses establish latent permanent infections in their hosts, although clinical signs of disease may not be detected. (medscape.com)

Finally, there are several known instances of viral miRNAs targeting host genes (Figure 1d ). (biomedcentral.com)
a) Endogenous host miRNAs target specific host genes. (biomedcentral.com)
b) Host miRNAs target viral genes. (biomedcentral.com)
This is likely due to the high supply rate of de novo variation and common evolutionary adaptations to the ferret host regardless of obesity status, which we show are mediated by variation in the hemagglutinin (HA) and polymerase genes (PB2 and PB1). (bvsalud.org)

Viral and host genetic factors contribute to pathophysiology of HIV-1 associated CNS dysfunction. (nih.gov)
Study the role of viral epigenetic factors in the pathophysiology of HIV-1 associated CNS dysfunction. (nih.gov)

The reported incidence of viral pneumonia (see the image below) has increased during the past decade. (medscape.com)
Depending on the virulence of the organism, as well as the age and comorbidities of the patient, viral pneumonia can vary from a mild, self-limited illness to a life-threatening disease. (medscape.com)
Viral pneumonia decreases in frequency in healthy young and middle-aged adults, but it then increases substantially among the elderly. (medscape.com)

Symptoms of the viral illness occur as a result of cell damage, tissue destruction, and the associated immune response. (medicinenet.com)

However, it is not clear whether there are general patterns underlying cellular targets of viral miRNAs. (biomedcentral.com)

Here we report a novel approach to characterizing viral AS using whole transcriptome dataset from host species. (nature.com)
Bats and pangolins currently have the greatest support as ancestral hosts of SARS-CoV-2, with the strong caveat that sampling of wildlife species for coronaviruses has been limited. (nih.gov)
Contributors to the Viral Theory collection of essays will enter into conversation with Povinelli, who engages with the virus as the popular cultural figure of the zombie-Life turned to Nonlife and transformed into a new kind of species war-the aggressive rotting undead against the last redoubt of Life. (e-flux.com)

Evaluation of SC2 strains demonstrated impressive genetic variability, and many of these viral variants are now defined as variants of concern (VOC) that cause enhanced transmissibility, decreased susceptibility to antibody neutralization or therapeutics, and/or the ability to induce severe disease. (elifesciences.org)
Despite these obese-specific variants, overall viral genetic diversity did not differ significantly between obese and lean hosts. (bvsalud.org)
Wuhan strain will continue to arise, yet not all viral variants generated through mutation of the virus are important or have immediate public health relevance. (who.int)

I'll turn it over to you, Bob, to tell us a bit about the viral tweet about your recent experience with COVID. (medscape.com)
gov/coca as we intend to host COCA calls to keep you informed of the latest guidance and updates on COVID-19. (cdc.gov)

It is believed to chronically persist in salivary gland tissue in some hosts, and oral shedding is the probable route of disease transmission. (medscape.com)

METHODS: TRIM22 exons three and four were sequenced by Sanger sequencing and single nucleotide polymorphisms were associated with markers of disease progression (CD4+ T-cell count and HIV viral load) and clinical indicators of advanced HIV disease (presence of stunting and chronic diarrhoea). (lu.se)
TRIM22 genotype and haplotypes were not associated with CD4+ T-cell count, HIV-1 viral load, stunting or chronic diarrhoea. (lu.se)

On the night of their arrival, however, a racist exchange with their Airbnb host left them reeling - and searching for alternate accommodations in the middle of the night. (cbsnews.com)
Last night, a group of friends and I reserved an Airbnb in NYC, and encountered a racist and rude host. (cbsnews.com)
Our hope is that someone else doesn't have to encounter a racist Airbnb hosts like Kate. (cbsnews.com)
The internet's appetite for Airbnb horror stories knows no bounds, and the latest story going viral is really catching its attention. (indy100.com)

Stool samples from an outbreak that are submitted to CDC for detection of viral pathology should be collected in bulk from 10 ill persons during their first 48 hours of illness, while feces are still liquid, and should be stored at 4 C (not frozen). (cdc.gov)
Health-care facilities involved in the detection of rotavirus or the other viral agents of diarrhea can participate. (cdc.gov)

In addition to increased affinity and neutralization potency, antibody evolution changed the mutational pathways for the acquisition of viral resistance and restricted neutralization escape options. (nih.gov)

In addition, pmoC-phage abundance patterns correlate with those of the coexisting bacterial methanotrophs, supporting host-phage relationships. (nature.com)

Examine the role of host genetic factors, including epigenetic mechanisms in regulating susceptibility to HIV-1 associated CNS dysfunction. (nih.gov)
Therefore, we provide critical information about triterpenoids as potential antiviral agents targeting entry and release, focusing specifically on the emerging aspect of triterpenoid-mediated inhibition of a variety of virus-host membrane fusion mechanisms via a trimer-of-hairpin motif. (physiciansweekly.com)
Intriguingly, novel mechanisms are continuously uncovered, which elucidate a more concrete picture of cGAS-STING involvement in viral evasion. (frontiersin.org)

Study host genetic factors involved in regulating responsiveness to antiretroviral therapy and neuroprotective adjuvant therapies (pharmacogenomics). (nih.gov)

In funnier news, a viral video from a halloween-themed night might be my new favorite thing on the internet. (yahoo.com)
A recent viral video featuring Joe Biden shows just how simple it is to push disinformation with very little effort. (mediamatters.org)
Catcher should have been ejected," one viewer wrote after seeing the viral video on Facebook . (kxnet.com)

This program supports basic and clinical research to determine the viral and host genetic factors involved in central nervous system (CNS) impairment caused by HIV-1 worldwide. (nih.gov)

Host shift events play an important role in epizootics as adaptation to new hosts can profoundly affect the spread of the disease and the measures needed to control it. (gla.ac.uk)
Our study provides the first insight into the consequences of host obesity on viral genetic diversity and adaptation, suggesting that host factors associated with obesity alter the selective environment experienced by a viral population , thereby impacting the spectrum of genetic variation . (bvsalud.org)

The National Institute of Mental Health (NIMH) and The National Institute of Neurological Disorders and Stroke (NINDS) solicit research grant applications to supp ort studies focused on viral and host genetic factors involved in HIV-1 Associated Neurocognitive Disorders (HAND) in the setting of highly active anti-retroviral therapy (HAART). (nih.gov)

This study suggested that the number of viral miRNA targets in the host may be much greater than previously assumed and are specific to host pathways. (biomedcentral.com)

The delta variant also accumulates at high concentrations in host tissues and has caused waves of lethal disease. (elifesciences.org)
Kathleen Hall Jamieson compares "viral deception" on the web to "venereal disease. (cnn.com)
These types have different disease patterns in their hosts. (medscape.com)
TRIM22 is a host restriction factor, which directly inhibits HIV-1 transcription, and its genotype variation is associated with disease progression in adults. (lu.se)

In other cases, virus particles "bud" off the host cell over a period of time before killing the host cell. (medicinenet.com)
The virus makes more copies of itself, releases new virus particles, and kills more host cells. (medicinenet.com)

Dengue diversity across spatial and temporal scales: Local structure and the effect of host population size. (cdc.gov)

she then asks, utilizing a racial epithet, which has now incensed social media users across the world and revived the viral hashtag #AirbnbWhileBlack. (cbsnews.com)
We've probably all stated in places that have certain rules we're expected to follow, but one host has taken it to the extreme - and managed to attract the ire of social media users as a result. (indy100.com)
These are all examples of the most viral products that have hit social media. (socialmediaclub.org)
As mentioned above, staying updated on the current trends of social media is a big aspect in going viral, creating old viral content that has oversaturated the markets and releasing content people have already seen is not the key to viral marketing. (socialmediaclub.org)
BEIJING (Reuters): A viral clip online likely shows the catkins, or flower spikes, of poplar trees covering cars in northern China, not a "rain of worms" as social media posts and some news reports have claimed, experts told Reuters. (thefrontierpost.com)

Anatomy25

Organisms74

Diseases18

Chemicals and Drugs33

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Psychiatry and Psychology3

Phenomena and Processes80

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture2

Information Science4

Health Care9

Replication11

Infection28

Went viral5

Protein8

TikTok6

Interactions5

Proteins12

Hepatitis2

Genome4

Viruses22

Pathogens1

Common viral cause1

Mediate1

Symptoms of viral1

Molecular2

Genomic1

Influenza3

Genomes3

Anti-viral1

Gone viral2

Interaction2

RNAs2

Mutations2

Infections6

Genes4

Pathophysiology2

Pneumonia3

Immune1

MiRNAs1

Species3

Variants3

Covid2

Tissue1

Chronic2

Airbnb4

Detection2

Evolution1

Bacterial1

Mechanisms3

Antiretroviral therapy1

Video3

Clinical1

Adaptation2

Genetic factors1

Pathways1

Disease4

Particles2

Diversity1

Social media5