AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth CareGeographicals
Hepatitis AntigensHepatitis AHepatitis BHepatitis, Viral, HumanHepatitis CHepatitis B virusHepatitis B Surface AntigensHepatitis B, ChronicHepatitis C, ChronicHepatitisHepatitis A virusHepatitis, ChronicHepatitis B AntibodiesHepatitis B VaccinesHepatitis B AntigensHepatitis AntibodiesHepatitis A VaccinesHepatitis VirusesHepatitis B Core AntigensHepatitis, Viral, AnimalHepatitis EHepacivirusHepatitis A AntibodiesHepatitis B e AntigensHepatitis C AntibodiesHepatitis E virusHepatitis DAntigensHepatitis A Virus, HumanViral Hepatitis VaccinesHepatitis, AnimalHepatitis, AutoimmuneHepatitis Delta VirusHepatovirusLiver CirrhosisAntiviral AgentsAlanine TransaminaseMurine hepatitis virusLiverAntigens, BacterialJaundiceCarcinoma, HepatocellularLiver DiseasesInterferon-alphaAntigens, ViralRNA, ViralAntigens, NeoplasmLiver NeoplasmsHepatitis C AntigensAntigens, SurfaceHepatitis, AlcoholicRibavirinHepatitis delta AntigensAcute DiseaseHepatitis A AntigensDNA, ViralLiver Function TestsHepatitis B Virus, WoodchuckAspartate AminotransferasesSeroepidemiologic StudiesMolecular Sequence DataHepatitis B Virus, DuckHepatitis D, ChronicMarmotaViral Nonstructural ProteinsLiver TransplantationVirus ReplicationLamivudinePrevalencePolyethylene GlycolsGenotypeDrug-Induced Liver InjuryHepatocytesBlood DonorsCarrier StateEnzyme-Linked Immunosorbent AssayChronic DiseaseRecombinant ProteinsBilirubinLiver Failure, AcuteHepatic EncephalopathyBase SequenceViral Core ProteinsViral LoadHLA AntigensAntigens, ProtozoanRisk FactorsAntigens, CDAntigens, Polyomavirus TransformingHIV InfectionsEgyptSerologic TestsImmunoglobulin MAntibodies, ViralCell LineImmunoglobulin GLiver FailurePan troglodytesPolymerase Chain ReactionVaccination
HBsAgHBeAgInfectionsAntibodies to hepatitis B coreReplicationDivision of Viral HepatitisForms of viral hepatitisVirusesPrevalenceVaccinationHepatocellularHepaticEnzyme immunoassayImmunoglobulinRisk of hepatitisEtiologyDiagnosisJaundiceAntibody to hepatitisVaccineProteinsNational Center for HIVSurface antibodyCaused by Hepatitis B virProteinInhibitsAutoimmune HepatitisCirrhosis and liver cancerLiver cirrhosisFulminant hepatitisCases of acuteDetectionEndemicHBcAgInfectiousCoreDeoxyribonucleic acidImmunityClinicalCohortSustained viral responsePatientsSymptoms of hepatitisCentersInfection of the liverChronic infectionType of hepatitisTypes of hepatitisAntiviral treatmentSpread of hepatitis
HBsAg12
  • Results: Homozygosity for KIR group A gene-content haplotype was associated with HBsAg carriage (OR 3.7, 95% CI 1.4-10.0) whilst telomeric A genotype (t-AA) was associated with reduced risk of e antigenaemia (OR 0.2, 95% CI 0.0-0.6) and lower viral loads (mean log viral load 5.2 vs. 6.9, pc = 0.022). (edgehill.ac.uk)
  • We determined the serum level of antibody to hepatitis B surface antigen (anti-HBsAg) in 273 randomly selected 7-9-year-old schoolchildren from Zanjan City, Islamic Republic of Iran, who had been fully vaccinated against hepatitis B starting at birth. (who.int)
  • B surface antigen (HBsAg) mutants, their impact on viral to an amino acid change in the overlapping reading frame. (cdc.gov)
  • 1973 and 1978, Dr Rinchin carried out research on hepatitis B surface antigen (HBsAg) and its detection, HBsAg being the primary marker of hepatitis B virus infection. (who.int)
  • Investigators estimated the incidence of HBsAg seroclearance in patients with hepatitis B virus infection on long-term therapy with entecavir or tenofovir disoproxil fumarate. (clinicaladvisor.com)
  • 4 In a local epidemiological study conducted between 2015 and 2016, the seroprevalence of hepatitis B surface antigen (HBsAg) was estimated at 7.8% among the general population. (hkmj.org)
  • Serum samples from all study subjects were tested for hepatitis B surface antigen (HBsAg) and antibodies to HCV (anti-HCVs) by enzyme immunoassays, as well as HCV RNA by reverse transcription-PCR assays. (aacrjournals.org)
  • The laboratory diagnosis focuses on the detection of the hepatitis B surface antigen HBsAg. (apollohospitals.com)
  • Acute HBV infection is accompanied by the presence of HBsAg and immunoglobulin M (IgM) antibody to the core antigen, HBcAg. (apollohospitals.com)
  • The objective of this study were to assess the prevalence of hepatitis B surface antigen (HBsAg) carrier status in the community in a district in Sri Lanka and the prevalence and some risk factors of hepatitis B infection among nursing personnel in the same district. (who.int)
  • For example, a hepatitis B surface antigen (HBsAg) level of less than 1 s/c is considered negative, while a level more than 5 s/c is considered positive. (medscape.com)
  • HBsAg usually appears 4 weeks after viral exposure but can be detected any time after the first week. (medscape.com)
HBeAg7
  • Hepatitis B e antigen (HBeAg) is an important serological marker of hepatitis B virus (HBV) infection and is associated with higher levels of viremia, increased risk of infectivity to others and increased risk of hepatocellular carcinoma. (rhapp.org)
  • We analyzed HBeAg status in a large cohort of adults and children enrolled in Cohort Studies of the Hepatitis B Research Network, long-term natural history studies of chronic HBV infection. (rhapp.org)
  • When both HBcAg and HBeAg proteins are present, it acts as a marker of viral replication, and antibodies to these antigens indicates declining replication. (wikipedia.org)
  • Treatment of adult patients with chronic hepatitis B associated with evidence of hepatitis-B viral replication (presence of DNA of hepatitis-B virus (HBV-DNA) and hepatitis-B antigen (HBeAg), elevated alanine aminotransferase (ALT) and histologically proven active liver inflammation and / or fibrosis. (europa.eu)
  • During the initial phase of infection, patients are also seropositive for hepatitis B e antigen (HBeAg). (apollohospitals.com)
  • In hepatitis B e-antigen (HBeAg) positive persistent hepatitis B, unconstrained or treatment-induced clearance of HBeAg and seroconversion to anti-HBe is ordinarily taken after by a longterm period of low-level replication, which may be named supported virologic reaction (SVR). (alliedacademies.org)
  • Proposed cutoffs for consideration for antiviral therapy is 100,000 copies/mL or 20,000 IU/mL in HbeAg-positive patients with chronic hepatitis and 10,000 copies/mL or 2,000 IU/mL in HbeAg-negative patients. (medscape.com)
Infections14
  • Natural Killer (NK) cells protect against viral infections and tumours by killing abnormal cells recognised by Killer-cell Immunoglobulin-like Receptors (KIR). (edgehill.ac.uk)
  • The medical definition of hepatitis E is a kind of inflammation and swelling of the liver that is caused by the hepatitis E virus (hep E). There are about 20 million cases of hep E infections per year in the world. (medicinenet.com)
  • Most hep E infections happen in parts of the world that have poor sanitation or unsafe water supplies. (medicinenet.com)
  • Current evidence suggests that environmental factors, including viral infections, are implicated as possible triggers. (iasp-pain.org)
  • Hepatitis viruses constitute a major public health problem because of the morbidity and mortality associated with the acute and chronic consequences of these infections. (cdc.gov)
  • NHANES testing for markers of infection with hepatitis viruses will be used to determine secular trends in infection rates across most age and racial/ethnic groups, and will provide a national picture of the epidemiologic determinants of these infections. (cdc.gov)
  • In the light of this, he advocated the rapid adoption of health practices to reduce the number of infections with hepatitis B virus, namely improvement of sterilization of injection equipment and medical instruments, and an increase in hepatitis B vaccination rates. (who.int)
  • Although the rate of acute hepatitis B virus (HBV) infections have declined approximately 89% during 1990-2011, from 8.5 to 0.9 cases per 100,000 population in the United States, the risk for occupationally acquired HBV among HCP persists, largely from exposures to patients with chronic HBV infection. (cdc.gov)
  • Liver inflammation, or hepatitis, a combination of the Greek words for liver and inflammation, is mainly caused by viral infections, although alcohol abuse, environmental toxins and autoimmune disease are also important causes. (vhpb.org)
  • Mutual confounding and interactive effects between hepatitis C and hepatitis B viral infections in hepatocellular carcinogenesis: a population-based case-control study in Taiwan. (aacrjournals.org)
  • A series of blood tests are available to diagnose and monitor people with Hepatitis B and more importantly, to distinguish acute and chronic infections. (apollohospitals.com)
  • Incessant contamination with either hepatitis B or hepatitis C infections (HBV and HCV) is related with significant dreariness and mortality around the world [ 2 ]. (alliedacademies.org)
  • The course of most viral infections is not affected by pregnancy. (medscape.com)
  • The differential diagnosis includes other forms of viral hepatitis including mononucleosis and Epstein-Barr virus (EBV) infections, autoimmune disease, and widespread systemic infection with liver failure. (medscape.com)
Antibodies to hepatitis B core2
Replication16
  • Replication of the hepatitis B virion is, therefore, the sole of the issues associated with detection of mutants in requirement for generating these nucleotide mismatch healthcare settings. (cdc.gov)
  • Moreover, for delta hepatitis, we are finally on the road to being able to achieve the same goals as hepatitis B through the development of drugs that block viral replication with the hope that they can also be effective for a definitive recovery. (mdpi.com)
  • CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro. (uc.edu)
  • HCV induces the expression of Rubicon and UVRAG to temporally regulate the maturation of autophagosomes and viral replication PLoS Pathog. (usc.edu)
  • Viral-load-dependent effects of liver injury and regeneration on hepatitis B virus replication in mice J Virol. (usc.edu)
  • Replication of hepatitis C virus RNA on autophagosomal membranes J Biol Chem. (usc.edu)
  • Enhancement of hepatitis B virus replication by androgen and its receptor in mice J Virol. (usc.edu)
  • Hepatitis C virus translation preferentially depends on active RNA replication PLoS One. (usc.edu)
  • Autophagy required for hepatitis B virus replication in transgenic mice J Virol. (usc.edu)
  • Effects of interferon-a/ß on HBV replication determined by viral load PLoS Pathog. (usc.edu)
  • Krüppel-like factor 15 activates hepatitis B virus gene expression and replication Hepatology. (usc.edu)
  • Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo J Virol. (usc.edu)
  • NUCs may repress the movement of HBV polymerase, in this manner hindering viral replication and diminishing the infection stack, which was the short-term objective. (alliedacademies.org)
  • In patients with chronic hepatitis B, determined viral replication is related with movement of liver illness and treatment is pointed at maximal viral concealment. (alliedacademies.org)
  • The detection of HCV replication in B cells would support the hypothesis of direct virus-mediated lymphomagenesis, where the virus could trigger oncogenic events via intracellular viral proteins. (nih.gov)
  • HBV DNA (quantitative viral load) indicates viral burden and viral replication. (medscape.com)
Division of Viral Hepatitis2
  • Vials are stored under appropriate frozen (-30°C) conditions until they are shipped to Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention for testing. (cdc.gov)
  • Title : Prevention of perinatal transmission of hepatitis B virus : prenatal screening of all pregnant women for hepatitis B surface antigen Corporate Authors(s) : National Center for Infectious Diseases (U.S.). Division of Viral Hepatitis. (cdc.gov)
Forms of viral hepatitis2
  • Morula-like cells" were more frequently found in HDV acute superinfection, as well as in HAV/HBV acute coinfection and acute HCV infection, and less often in other forms of viral hepatitis. (scielo.br)
  • With over 6 million Americans infected with one or more forms of viral hepatitis, practitioners must understand the impact this growing problem has on both their clients and their practice. (healthpositive.com)
Viruses12
  • Background: Hepatocellular carcinoma (HCC) causes over 800,000 deaths worldwide annually, mainly in low income countries, and incidence is rising rapidly in the developed world with the spread of hepatitis B (HBV) and C (HCV) viruses. (edgehill.ac.uk)
  • This Special Issue of the Viruses journal is dedicated to the diagnostic and therapeutic advancements of viral liver diseases with the aim of giving a complete update not only on the treatments currently available and future developments, but also on the still unmet needs in the management of special patient populations. (mdpi.com)
  • The most common cause of hepatitis is a group of viruses called hepatitis A , hepatitis B , and hepatitis C . A hepatitis panel is a blood test that checks to see if you have a hepatitis infection caused by one of these viruses. (medlineplus.gov)
  • Hepatitis viruses spread in different ways. (medlineplus.gov)
  • Prior to their work, the discovery of the Hepatitis A and B viruses had been critical steps forward, but the majority of blood-borne hepatitis cases remained unexplained. (vhpb.org)
  • We understand that more than viruses (primarily hepatitis A, B, and C), drugs, and alcohol can harm the liver and inhibit the process. (jonbarron.org)
  • This was my first time taking a course specific to Hepatitis viruses. (healthpositive.com)
  • The viruses that cause DVH in ducklings should not be confused with duck hepatitis B virus, a hepadnavirus infection of older ducks. (msdvetmanual.com)
  • The cell-to-cell transport of many plant viruses through plasmodesmata requires viral movement proteins (MPs) encoded by a 'triple gene block' (TGB) and termed TGB1, TGB2 and TGB3. (microbiologyresearch.org)
  • Acute viral hepatitis is diffuse liver inflammation caused by specific hepatotropic viruses that have diverse modes of transmission and epidemiologies. (msdmanuals.com)
  • The term acute viral hepatitis often refers to infection of the liver by one of the hepatitis viruses. (msdmanuals.com)
  • Other unidentified viruses probably also cause acute viral hepatitis. (msdmanuals.com)
Prevalence5
  • The prevalence of infection for at least 15 years, that antibody hepatitis B carriers varies in different parts levels decrease the most among persons of the world, ranging from less than 1% to immunized at 4 years of age or younger, and 15% [ 2 ]. (who.int)
  • Results: Out of 1860 patients seen in hepatogastroenterology consultation 422 had viral hepatitis B or C that is a prevalence of 22.7% and 41 patients were treated (9.7%) by Pegylated Interferon. (scirp.org)
  • Assessing HIV testing in hepatitis: an audit of HIV testing uptake in a specialist hepatology clinic in an area of high prevalence for hepatitis B and C. 3rd Joint BHIVA/BASHH Conference, 3-6 April 2014, Liverpool. (i-base.info)
  • The study consisted of four components, analysis of trends in viral hepatitis in Sri Lanka from the available records, a community based prevalence study, a cross sectional survey of nursing officers and an observational study on risk behaviours related to hepatitis B infection among the nursing officers. (who.int)
  • The prevalence rate of hepatitis B infection among nursing officers was 11.6 percent. (who.int)
Vaccination12
  • ABSTRACT The duration of protection after hepatitis B vaccination in children is unknown. (who.int)
  • In 1991, the World at least 6-8 years before with 3 doses of Health Organization (WHO) recommended hepatitis B vaccine starting at birth to that hepatitis B vaccination be included provide information on the effect of the in national immunization programmes in immunization strategy for hepatitis B and countries with a hepatitis B surface antigen the need for booster doses. (who.int)
  • It has been reported that when hepatitis services is good throughout the territory, B vaccination is initiated at birth, there and vaccinations are delivered through local is an increased likelihood that the child health districts which are able to reach the will complete the series [ 8,9 ] hence an whole population. (who.int)
  • There are no specific drugs or treatments to treat and cure hepatitis E, moreover, the only country that has a hep E vaccination is China at this time. (medicinenet.com)
  • It may also show that you are immune to certain types of hepatitis because you had a vaccination . (medlineplus.gov)
  • Explicit guidance is provided for persons working, training, or volunteering in health-care settings who have documented hepatitis B (HepB) vaccination years before hire or matriculation (e.g., when HepB vaccination was received as part of routine infant [recommended since 1991] or catch-up adolescent [recommended since 1995] vaccination). (cdc.gov)
  • This report emphasizes the importance of administering HepB vaccination for all HCP, provides explicit guidance for evaluating hepatitis B protection among previously vaccinated HCP (particularly those who were vaccinated in infancy or adolescence), and clarifies recommendations for postexposure management of HCP exposed to blood or body fluids. (cdc.gov)
  • Although a high proportion of healthy vaccine recipients in clinical trials respond to hepatitis B (HepB) vaccination, the proportion of responders can be lower among the general population, particularly among persons with chronic medical conditions ( 6 , 7 ). (cdc.gov)
  • How Can Hepatitis Vaccination Adherence Be Improved for At-Risk Adults? (clinicaladvisor.com)
  • Adults at risk of hepatitis A and hepatitis B have multi-dose vaccinations available, but complete and timely vaccination adherence rates are low. (clinicaladvisor.com)
  • Furthermore, 62.4% were aware of hepatitis B vaccination, whereas 19.0% knew that hepatitis C cannot be prevented by vaccination. (hkmj.org)
  • Comprehensive hepatitis education strategies should be developed to address gaps in knowledge among the Hong Kong public towards viral hepatitis, especially misperceptions relevant to social stigmatisation and the importance of preventive measures, including vaccination and screening, when exposed to risk factors. (hkmj.org)
Hepatocellular5
Hepatic5
  • Research in the group is focused on exploiting antigen presentation for immunotherapy to cure gastrointestinal and hepatic diseases. (erasmusmc.nl)
  • Figure 1 shows the presence of "morula-like" cells in hepatic tissue in the fulminant form of hepatitis A (HAV), B (HBV), C (HCV) and Delta (HDV). (scielo.br)
  • 5. Significant hepatic disease, including, but not limited to, chronic active hepatitis and/or severe hepatic insufficiency and/or significant abnormal liver function, including patients with Alanine transaminase (ALT) and/or Aspartate transaminase (AST) ≥3x ULN (Upper Limit of Normal)and/or Total Bilirubin ≥2.0x ULN. (astrazenecaclinicaltrials.com)
  • Vitamin D deficiency has been commonly present in patients with immune-mediated liver and non-liver diseases, and it has been associated with histological severity, advanced hepatic fibrosis, and non-response to conventional glucocorticoid therapy in autoimmune hepatitis. (springer.com)
  • Vitamin D analogues that are independent of hepatic hydroxylation constitute an investigational opportunity to supplement current management of autoimmune hepatitis. (springer.com)
Enzyme immunoassay1
Immunoglobulin2
  • The aim of this study was to examine the distribution of HLA Class II DRB1* alleles in a homogeneous cohort of individuals who were infected with HCV-contaminated anti-D immunoglobulin, and to compare frequencies of alleles in individuals with spontaneous viral clearance to those with chronic HCV infection. (nih.gov)
  • DRB1*01 is associated with spontaneous viral clearance in an Irish cohort infected with HCV via contaminated anti-D immunoglobulin. (nih.gov)
Risk of hepatitis3
  • If you think you might be at risk of hepatitis C, and you are pregnant, or thinking of becoming pregnant, ask for a hepatitis C test. (britishlivertrust.org.uk)
  • [ 7 ] The risk of hepatitis A infection is inversely proportional to the sanitation infrastructure available in a country. (medscape.com)
  • Different occupational settings, either in different health institutions or wards, were no associated with increased risk of hepatitis B infection. (who.int)
Etiology1
  • Learn about the history, etiology and pathophysiology of hepatitis, as well as how to differentiate between several viral hepatitis types, their associated symptoms, modes of transmission, preventive measures, treatments and risks. (healthpositive.com)
Diagnosis3
  • We emphasise the importance of preventive measures including screening, diagnosis, treatment, and care to effectively manage viral hepatitis in Hong Kong. (hkmj.org)
  • Diagnosis is by viral isolation or PCR. (msdvetmanual.com)
  • On clinical grounds, it is hugely difficult to tell Hepatitis B from other hepatitis cases due to viral agents and, hence, laboratory confirmation of the diagnosis is essential. (apollohospitals.com)
Jaundice7
  • Hepatitis E viral infection causes symptoms and signs, for example, soreness and swelling of the liver (hepatitis) and yellow eyes ( jaundice ). (medicinenet.com)
  • In folk medicine P. amarus has reportedly been used to treat jaundice, diabetes, otitis, diarrhoea, swelling, skin ulcer, gastrointestinal disturbances and blocks DNA polymerase in the case of hepatitis B virus during reproduction ( Oluwafemi and Debiri, 2008 ). (scialert.net)
  • Anicteric hepatitis (hepatitis without jaundice) occurs more often than icteric hepatitis in patients with HCV infection and in children with HAV infection. (msdmanuals.com)
  • Acute viral hepatitis is the most common cause of jaundice in pregnancy. (medscape.com)
  • Patients presenting with jaundice during pregnancy often require a workup to differentiate obstructive gall bladder or bile duct disease, severe preeclampsia, HELLP (hemolysis, elevated liver enzyme levels, low platelet count), or acute fatty liver of pregnancy from viral hepatitis. (medscape.com)
  • We report on a 57-year-old man followed as an outpatient for chronic hepatitis C who presented to the emergency department for abdominal pain with abdominal distention and jaundice, occurring two months after treatment by direct-acting antiviral (DAA). (bvsalud.org)
  • Age, duration of employment, history of a needle prick injury and past illness with jaundice in the nursing officer, and/or in the spouse and in a family member were found to be risk factor for hepatitis B infection. (who.int)
Antibody to hepatitis1
  • ACIP also recommends that vaccinated HCP receive postvaccination serologic testing (antibody to hepatitis B surface antigen [anti-HBs]) 1-2 months after the final dose of vaccine is administered (CDC. (cdc.gov)
Vaccine6
Proteins3
  • Hepatitis antibodies are proteins that your immune system makes to help fight a hepatitis infection. (medlineplus.gov)
  • On the assumption that antibodies against the virus would be present in blood taken from hepatitis patients, the investigators used patient sera to identify cloned viral DNA fragments encoding viral proteins. (vhpb.org)
  • Plant viral movement proteins: agents for cell-to-cell trafficking of viral genomes. (microbiologyresearch.org)
National Center for HIV1
  • Reported results for all assays meet the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention's quality control and quality assurance performance criteria for accuracy and precision_rules. (cdc.gov)
Surface antibody1
  • For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. (medscape.com)
Caused by Hepatitis B vir1
Protein5
  • HBcAg (core antigen) is a hepatitis B viral protein. (wikipedia.org)
  • The evaluation also revealed normal or negative tests for antinuclear antibody (ANA) and antibodies to extractable nuclear antigens (ENA), antiphospholipid antibody panel, complement levels (C3, C4), serum and urine protein electrophoresis, antineutrophil cytoplasmic antibody (ANCA) screening, viral hepatitis panel, and tests for cryoglobulins and cold agglutinins. (medscape.com)
  • Technical standards for hepatitis B virus X protein (HBx) research Hepatology. (usc.edu)
  • The X-linked tumor suppressor TSPX interacts and promotes degradation of the hepatitis B viral protein HBx via the proteasome pathway PLoS One. (usc.edu)
  • Results from this study will confirm the existence of extrahepatic reservoirs for HCV and provide more direct evidence of viral protein expression in HCV associated lymphoma. (nih.gov)
Inhibits2
  • Thus, blockade of activating FcγR inhibits binding of opsonized antigens, induction of effector functions and secretion of pro-inflammatory cytokines by macrophages, and degranulation of granulocytes. (academie-medecine.fr)
  • Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes J Immunol. (usc.edu)
Autoimmune Hepatitis4
  • Hepatitis E Viral Association with Autoimmune Hepatitis: A Viral Trigger or Cross-Reactivity. (iasp-pain.org)
  • The goals of this review are to describe the nature of these expanded roles, examine the implications of vitamin D deficiency in autoimmune hepatitis, and identify opportunities for future investigation. (springer.com)
  • In conclusion, vitamin D has properties that could ameliorate immune-mediated disease, and vitamin D deficiency has been a common finding in immune-mediated liver and non-liver diseases, including autoimmune hepatitis. (springer.com)
  • Beyazit Y, Kocak E, Tanoglu A, Kekilli M. Oxidative stress might play a role in low serum vitamin D associated liver fibrosis among patients with autoimmune hepatitis. (springer.com)
Cirrhosis and liver cancer2
  • This year's Nobel Prize is awarded to three scientists who have made a decisive contribution to the fight against blood-borne hepatitis, a major global health problem that causes cirrhosis and liver cancer in people around the world. (vhpb.org)
  • A potentially life-threatening liver infection, Hepatitis B is caused by the Hepatitis B virus which can result in chronic infection to the point of high risk of death from cirrhosis and liver cancer. (apollohospitals.com)
Liver cirrhosis4
Fulminant hepatitis2
Cases of acute2
Detection2
  • A hepatitis C virus core antigen assay is a cost-effective, sensitive and specific test in the detection of acute hepatitis C in HIV infected subjects. (i-base.info)
  • Hepatitis B virus (HBV) testing plays an important role in detection, classification, and management of HBV disease . (medscape.com)
Endemic2
  • His findings demonstrated that hepatitis B was endemic in Mongolia and that it affected mainly children. (who.int)
  • Study of records showed that Sri Lanka has an endemic pattern of viral hepatitis with a slight downward trend in the mortality during the past 13 years. (who.int)
HBcAg1
Infectious6
  • this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). (wikipedia.org)
  • Clinicians are advised to refer frequently to HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C , the most recent recommendations of the American Association for the Study of Liver Diseases (AASLD) and Infectious Diseases Society of America (ISDA). (medscape.com)
  • In the 1940's, it became clear that there are two main types of infectious hepatitis. (vhpb.org)
  • It was a great source of concern that a significant number of those receiving blood transfusions developed chronic hepatitis due to an unknown infectious agent. (vhpb.org)
  • Duck viral hepatitis is an acute infectious disease affecting young ducklings. (msdvetmanual.com)
  • Positive serologic evidence of current infectious liver disease, including patients who are known to be positive for Hepatitis viral antibody ImmunoglobulinM (IgM), Hepatitis B surface antigen, and Hepatitis C virus antibody. (astrazenecaclinicaltrials.com)
Core8
  • Florea D, Neaga E, Nicolae I, Maxim D, Popa M, Otelea D. Clinical Usefulness of HCV Core Antigen Assay for the Management of Patients with Chronic Hepatitis C. JGLD [Internet]. (jgld.ro)
  • The study aimed to evaluate the clinical utility of the chemiluminescent HCV core Ag test compared to viral load assessment in the management of patients with chronic hepatitis C. (jgld.ro)
  • Seventy-six samples were tested with the Architect HCV core Antigen kit and Cobas AmpliPrep/Cobas Taqman HCV kit. (jgld.ro)
  • Recombinant Hepatitis B virus core antigen, amino acids 1-183. (bio-rad-antibodies.com)
  • Routine monitoring for viral hepatitis, at least annually, is recommended for HIV positive people in BHIVA guidelines and this may be improved by use of HCV core antigen testing. (i-base.info)
  • Several groups reported on their experience from using HCV core antigen test which has been available for about a year and that has advantages of two-hour turnaround and lower cost (~20% compared to PCR), and the potential to help diagnose acute HCV. (i-base.info)
  • Results from the use of core antigen testing from 2013 at St Georges Hospital in south London were reported from a retrospective case note review of 75 patients tested for HCV. (i-base.info)
  • Core antigen testing also identified 14 people, with one indeterminate result that did not become positive by either test. (i-base.info)
Deoxyribonucleic acid1
  • Serum HBV-DNA (hepatitis B virus deoxyribonucleic acid) and HDV-RNA (hepatitis D virus ribonucleic acid) were assayed using molecular hybridization technique, as previously described 3,18 . (scielo.br)
Immunity3
  • Chronic hepatitis E is more common in most people with hepatitis C . However, hep E occurs less often than hep B , and very rarely, with hep E can become chronic in people whose immunity is suppressed by drugs given to prevent rejection of a transplanted organ. (medicinenet.com)
  • After an antigen binds to a BCR, the B cell activates to proliferate and differentiate into either plasma cells , which secrete soluble antibodies with the same paratope, or memory B cells , which survive in the body to enable long-lasting immunity to the antigen. (wikipedia.org)
  • Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission Immunity. (usc.edu)
Clinical5
  • Similar clinical and histologic features of Labrea Hepatitis were found in northern Colombia 5 , western Venezuela 16 and Central African Republic 17 . (scielo.br)
  • Objectives: To assess the efficacy of Pegylated Interferon in clinical practice in patients with chronic viral hepatitis B and C and determine the hematologic side effects. (scirp.org)
  • The aims of our work were to assess the effectiveness of treatment with PEG-INF alone or in combination with Ribavirin (RBV) in clinical practice in patients with chronic hepatitis B or C and to determine the hematologic side effects. (scirp.org)
  • June 25, 2022 (GLOBE NEWSWIRE) -- Arbutus Biopharma Corporation (Nasdaq: ABUS), a clinical-stage biopharmaceutical company leveraging its extensive virology expertise to develop novel therapeutics that target specific viral diseases, today announced the presentation of new clinical and pre-clinical data from its proprietary compounds at the European Association for the Study of the Liver (EASL) International Liver Congress™ (ILC). (biospace.com)
  • The new clinical data for AB-729, our RNAi therapeutic, continues to support its development as a potential cornerstone agent for the treatment of chronic hepatitis B (cHBV) infection. (biospace.com)
Cohort3
  • Hepatitis E Infection in a Longitudinal Cohort of HCV and HCV/HIV Coinfected Persons. (uc.edu)
  • Patients and Methods: A descriptive retrospective study from January 2012 to November 2013 on a cohort of patients chronic carriers of hepatitis B virus (n = 11) treated with Pegylated Interferon to 180 mcg per week and hepatitis C virus (n = 30) treated with a combination therapy associating pegylated Interferon to 180 mcg per week and Ribavirin assayed according to the genotype. (scirp.org)
  • P236, Viral hepatitis testing patterns among HIV-positive individuals in the UK Collaborative HIV Cohort (UKCHIC) study. (i-base.info)
Sustained viral response2
  • For HCV, there was 52.94% of cases of sustained viral response (SVR) including 44.44% of genotype 1, 83.33% of genotype 2 and 100% of genotype 4. (scirp.org)
  • States and territories may choose to track resolved hepatitis C cases in which spontaneous clearance of infection or sustained viral response to treatment are suspected to have occurred before national notification or are known to have occurred after national notification as a confirmed or probable case to CDC. (cdc.gov)
Patients9
  • More than 10,000 patients are hospitalized with hepatitis B each year, and an average of 250 die of fulminant disease. (cdc.gov)
  • At that time, Harvey J. Alter at the US National Institutes of Health was studying the occurrence of hepatitis in patients who had received blood transfusions. (vhpb.org)
  • Alter and his colleagues showed that blood from these hepatitis patients could transmit the disease to chimpanzees, the only susceptible host besides humans. (vhpb.org)
  • Findings emphasize the importance of strategies to help HBV-HIV coinfected patients maximize antiretroviral adherence to achieve hepatitis B viral suppression. (clinicaladvisor.com)
  • Following "the Dakar Appeal" [3] , the Ivorian government, through the National Program of the Fight against Viral Hepatitis (NPFVH) has made freely available to patients of the 3 Teaching Hospitals of Abidjan, Pegylated Interferon (PEG-IFN) from February 2012 to November 2013 for the treatment of chronic hepatitis B and C. The pre, per and post therapeutic biological, radiological and histological tests remain the responsibility of patients. (scirp.org)
  • We carried out a study on the results of treatment with PEG-IFN, in patients with chronic hepatitis during this period at the Teaching Hospital of Yopougon in Abidjan in the Ivory Coast. (scirp.org)
  • Four patients had new HCV infection including one acute case, three with known HCV (both antigen and antibody positive) and nine were antigen negative and antibody positive (indicated cleared HCV infection). (i-base.info)
  • A small section of patients with acute hepatitis may develop acute liver failure which can be fatal. (apollohospitals.com)
  • Association of sustained virological response in patients with chronic Hepatitis B. (alliedacademies.org)
Symptoms of hepatitis2
Centers1
Infection of the liver1
Chronic infection3
  • The DRB1*01 allele was found significantly more frequently in individuals with viral clearance compared to those with chronic infection (27.4% vs. 7.1% p = 0.001, odds ratio OR = 4.9, pc = 0.01). (nih.gov)
  • Most people who get hepatitis C will have a chronic infection. (medlineplus.gov)
  • Presence of the antigen longer than 6 months after initial exposure indicates chronic infection. (medscape.com)
Type of hepatitis2
Types of hepatitis1
Antiviral treatment1
  • Conclusion: The free antiviral treatment program helped treat 10% of chronic viral hepatitis B and C. Our results are not different from those of the literature. (scirp.org)
Spread of hepatitis1