Viral hemorrhagic fever defective viruses. Medical search. Frequent questions

None of the immunized monkeys develop disease and they rapidly control viral replication. (bvsalud.org)
However, we observed that endocytosis-defective DC-SIGN molecules allow efficient DV replication, indicating that DC-SIGN endocytosis is dispensable for the internalization step in DV entry. (unboundmedicine.com)
The GV-MVA-VLP TM derived vaccines can elicit durable immune responses in the host similar to a live-attenuated virus, while typically providing the safety characteristics of a replication-defective vector. (gabio.org)
An exogenous virus transmitted by sexual intercourse is the perfect trigger for replication at sexual maturity. (phoenixrising.me)
Besides their function in the virus replication cycle, the viral glycoprotein, nucleoprotein, minor matrix protein and polymerase cofactor are viral determinants of pathogenicity, with evasion of the host innate and adaptive immune responses as the main mechanism. (biomedcentral.com)
Antisense therapies, in which oligonucleotides inhibit viral replication, have shown promising results in non-human primates following post-exposure treatment. (biomedcentral.com)
Measles virus induces persistent infection by autoregulation of viral replication. (tci-thaijo.org)
Like all viruses, the EBOV largely relies on host cell factors and physiological processes for its entry, replication, and egress. (biomedcentral.com)
The involvement of viral DNA-binding proteins in the regulation of virulence genes, transcription, DNA replication, and repair make them significant targets. (mdpi.com)
In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. (lookformedical.com)
Virus Oncolitici 0 domande Tumor-selective, replication competent VIRUSES that have antineoplastic effects. (lookformedical.com)

Animals immunized eight days before the challenge are the best controllers, producing a strong CD8 T-cell response against the viral glycoprotein. (bvsalud.org)
Binding of mannosylated N-glycans on DV E protein to DC-SIGN triggers a rapid and efficient internalization of the viral glycoprotein. (unboundmedicine.com)
Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection. (prolekarniky.cz)
ZMapp), anti-sense phosphorodiamidate morpholino oligomers (PMO AVI-6002), lipid nanoparticle small interfering RNA (LNP-siRNA: TKM-Ebola), and an EBOV glycoprotein-based vaccine using live-attenuated recombinant vesicular stomatitis virus (rVSV-EBOGP) or a chimpanzee adenovirus (rChAd-EBOGP)-based vector. (biomedcentral.com)

Combined efforts of prevention and therapeutic intervention are required to tackle highly variable RNA viruses, whose infections often lead to outbreaks. (bvsalud.org)
In addition, fever begins to subside, and infections often begin to clear. (medscape.com)
The greatest challenges at this time include management of GVHD and prevention of viral infections, especially cytomegalovirus (CMV). (medscape.com)
Ebola virus (EBOV) infections are characterized by a pronounced lymphopenia that is highly correlative with fatalities. (prolekarniky.cz)
Finally, a summary of the immune biomarkers that have been reported for dengue and Zika viral infections are discussed which may be useful indicators for future anti-viral targets or predictors for disease severity. (frontiersin.org)
Together, this information appraises the current understanding of both Zika and Dengue infections, providing insights for future vaccine design approaches against both viruses. (frontiersin.org)
GeoVax's current development programs are focused on preventive vaccines against COVID-19, HIV, Zika, hemorrhagic fever viruses (Ebola, Sudan, Marburg, and Lassa), and malaria, as well as therapeutic vaccines against chronic Hepatitis B infections and multiple cancers. (gabio.org)
A 32-year-old Caucasian male, an outdoor worker (border guard), with mild, recurrent respiratory infections during two preceding years was admitted to the infectious diseases clinic with a 5-day history of high fever, chills, chest pain, dry cough and myalgia. (biomedcentral.com)
High fever and joint pain can appear acutely in other infections like dengue, malaria or filaria. (findmeacure.com)
Persistent and transient hepatitis B virus (HBV) infections in children born to HBV-infected mothers despite active and passive vaccination. (tci-thaijo.org)
Multiple virus infections in the honey bee and genome divergence of honey bee viruses. (tci-thaijo.org)
the status of current laboratory diagnostics for ebola and marburg virus infections is discussed in terms of the assays available and their interpretation. (liverpool.ac.uk)
Viral ills, for now, are hard to treat, although medical science has made progress in detecting and preventing infections and reducing their harms. (patrickmalonelaw.com)
Insects like mosquitos and ticks, of course, host and transmit many kinds of viral infections, including yellow fever, dengue, and encephalitis. (patrickmalonelaw.com)
1- A 1-year-old boy with a history of many bacterial, viral and fungal infections presents to his physician with chronic diarrhea. (pdfcoffee.com)
Viruses are also responsible for the common cold, childhood exanthems (such as chickenpox, measles, rubella), latent infections (such as herpes simplex), some cancers or lymphomas (such as Epstein-Barr virus), and diseases of all organ systems. (unboundmedicine.com)
The virus is harmless to macaques or may cause only a herpetic rash in macaques, but in humans it often produces fatal infections of the brain and meninges. (unboundmedicine.com)

Marburg virus (MARV) is a lipid-enveloped virus harboring a negative sense RNA genome, which has caused sporadic outbreaks of viral hemorrhagic fever in Sub-Saharan Africa. (uci.edu)
Outbreaks Chronology: Ebola Virus Disease 2018. (prolekarniky.cz)
Since its discovery in 1976, Ebolavirus has caused periodic outbreaks of viral hemorrhagic fever associated with severe and often fatal disease. (biomedcentral.com)
Ebolaviruses are known for their ability to cause devastating viral hemorrhagic fever outbreaks in humans and great apes, but the natural reservoir for EBOV has remained elusive for many years. (biomedcentral.com)

Infection with Ebola virus (EBOV) is responsible for hemorrhagic fever in humans with a high mortality rate. (bvsalud.org)
Dengue virus (DV) is a mosquito-borne flavivirus that causes hemorrhagic fever in humans. (unboundmedicine.com)
In 2007 to 2008 a large outbreak of viral hemorrhagic fever with a case-fatality rate of approximately 25% occurred in humans in Uganda. (biomedcentral.com)
Bender C, Hall H, Huang J, Klimov A, Subbarao K. Characterization of the surface proteins of influenza A (H5N1) viruses isolated from humans in 1997-1998. (unt.edu)
Cowpox virus "scarification" by Jenner, used to induce protective immunity against smallpox, is not a single species but a group of up to 5 virus species that infects cows, humans, and other animals. (medscape.com)
Answer: Acute Epstein Barr virus infectionThe Epstein-Barr virus is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. (passmed.uk)
They include both DNA and RNA viruses as well viruses from humans and animals. (lookformedical.com)

Sino Biological was the first to market with mammalian cell-made COVID-19 viral recombinant proteins and offers a full range of these and other bioreagents to complement and aid in COVID-19 vaccine development and has the world's largest selection of coronavirus research-grade products. (gabio.org)
On this platform, MVA, a large virus capable of carrying several vaccine antigens, expresses proteins that assemble into VLP immunogens within the person receiving the vaccine ( in vivo ). (gabio.org)
What's more, the complete viral genome requires two frame-shift events for efficient production of some proteins. (phoenixrising.me)
protective cytotoxic t-cell responses induced by venezuelan equine encephalitis virus replicons expressing ebola virus proteins. (liverpool.ac.uk)
GeoVax's GV-MVA-VLP TM vaccine platform utilizes modified vaccinia Ankara (MVA), a large virus capable of carrying several vaccine antigens, that expresses proteins that assemble into virus-like particles (VLP) immunogens in the person receiving the vaccine. (raiseworthy.com)
Proteins found in any species of virus. (lookformedical.com)
Proteins associated with the inner surface of the lipid bilayer of the viral envelope. (lookformedical.com)
These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell. (lookformedical.com)
The vaccinia virus A56 protein was one of the earliest-described poxvirus proteins with an identifiable activity. (microbiologyresearch.org)
The A56 protein is capable of binding two viral proteins, a serine protease inhibitor (K2) and the vaccinia virus complement control protein (VCP), and anchoring them to the surface of infected cells. (microbiologyresearch.org)

The two compounds inhibited EBOV infection in cell culture as well as infection by measles virus (MV) independently of IFN induction. (bvsalud.org)
Through viral load suppression, we may be able to prolong a patient's survival in order to provide a better chance for the patient to develop natural immune defense against the EBOV. (biomedcentral.com)
The EBOV is an enveloped filamentous RNA virus belonging to the family Filoviridae . (biomedcentral.com)
nearly thirty years after the first epidemics, ebola virus (ebov) remains hardly described, its transmission unclear and its reservoir elusive. (liverpool.ac.uk)
soon after the ebola fever outbreak and virus discovery in 1976 and in order to investigate the distribution of ebov in central africa, several countries including a range of ecological zones were investigated in the early 1980s, using extensive survey: central african republic (car), cameroon, chad, congo, gabon and equatorial guinea. (liverpool.ac.uk)

Here, we demonstrate that both viral mRNAs and antigens are detectable in CD4 + T cells despite the absence of productive infection. (prolekarniky.cz)
A protein phosphatase 1 inhibitor, 1E7-03, and siRNA-mediated suppression of viral antigens were used to demonstrate de novo synthesis of viral RNAs and antigens in CD4 + T cells, respectively. (prolekarniky.cz)
Nuclear antigens encoded by VIRAL GENES found in HUMAN HERPESVIRUS 4. (lookformedical.com)
Frequent mutations change some viral antigens so that the lymphocytes are unable to create an antibody that can neutralize the original antigen and its replacement. (unboundmedicine.com)
The common influenza viruses have antigens that mutate or combine readily, requiring new vaccines with each mutation. (unboundmedicine.com)

Genome condensation and packaging are essential processes in the life cycle of viruses. (mdpi.com)
Viral architecture is very complex, but every virus contains at least a genome and a capsid. (unboundmedicine.com)
The 400 known viruses are classified in several ways: by genome core (RNA or DNA), host (animals, plants, or bacteria), method of reproduction (such as retrovirus), mode of transmission (such as enterovirus), and disease produced (such as hepatitis virus). (unboundmedicine.com)
Virus Incompleti 0 domande Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. (lookformedical.com)
Provirus 0 domande Duplex DNA sequences in eukaryotic chromosomes, corresponding to the genome of a virus, that are transmitted from one cell generation to the next without causing lysis of the host. (lookformedical.com)
Virus Riassortanti 0 domande Viruses containing two or more pieces of nucleic acid (segmented genome) from different parents. (lookformedical.com)

DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated cytosine-guanosine (CpG) oligonucleotides, a motif often seen in bacterial or viral DNA. (uci.edu)
Batteriofagi 0 domande Viruses whose hosts are bacterial cells. (lookformedical.com)

They are not hard questions but USMLE still has some easy questions like those *A 34 year-old man presents to the ER complaining of fevers, chills, headache and malaise. (pdfcoffee.com)

Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly. (uci.edu)
Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses. (prolekarniky.cz)
laboratory diagnosis of ebola and marburg hemorrhagic fever. (liverpool.ac.uk)
Additional research and development programs include preventive vaccines against Zika Virus, hemorrhagic fever viruses (Ebola, Sudan, Marburg, and Lassa) and malaria, as well as immunotherapies for multiple solid tumors. (raiseworthy.com)

When viruses replicate in giant numbers, as they do, they also may undergo fundamental changes, notably in their DNA genetic code. (patrickmalonelaw.com)
The mechanism by which latent viruses, such as genetically transmitted tumor viruses ( PROVIRUSES ) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. (lookformedical.com)
Poxviridae are linear, double-stranded deoxyribonucleic acid (DNA) viruses that replicate in the cytoplasm. (medscape.com)
ABBR: AAV A genus in the parvovirus family whose members cannot replicate without the presence of another virus. (unboundmedicine.com)
A non-taxonomic designation for viruses that can replicate in both vertebrate hosts and arthropod vectors. (lookformedical.com)
Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. (lookformedical.com)
Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus. (lookformedical.com)
Virus Helper 0 domande Viruses which enable defective viruses to replicate or to form a protein coat by complementing the missing gene function of the defective (satellite) virus. (lookformedical.com)

When the Zika epidemic spread through the American continent and then later to Africa and Asia in 2015, researchers compared the characteristics of the Zika infection to Dengue, considering both these viruses were transmitted primarily through the same vector, the Aedes aegypti female mosquitoes. (frontiersin.org)
Meanwhile, the cross-reactivity of CD8+ and CD4+ T cells response to Dengue and Zika viruses provide important clues for further development of potential treatments. (frontiersin.org)

Viruses play an important role as vectors for inserting genetic information into other organisms. (wikipedia.org)
The application of viral vectors is limited because of their high immunogenicity and low capacity, while non-viral vectors are widely used because of their low immunogenicity, low production cost, and high safety. (bvsalud.org)
This paper reviews the common non-viral vectors in recent years and introduces their advantages and disadvantages, as well as the latest application examples. (bvsalud.org)

We previously developed MeV-NP, a single-shot vaccine protecting cynomolgus monkeys against divergent strains one month or more than a year before Lassa virus infection. (bvsalud.org)
Here, we test whether the time to protection can be reduced after immunization by challenging measles virus pre-immune male cynomolgus monkeys sixteen or eight days after a single shot of MeV-NP. (bvsalud.org)
Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection. (prolekarniky.cz)
Experimentally infected cynomolgus macaques ( Macaca fascicularis ) develop ordinary or hemorrhagic smallpox depending on the size of the inoculum. (medscape.com)

This study demonstrates that MeV-NP can induce a rapid protective immune response against Lassa fever in the presence of MeV pre-existing immunity but can likely not be used as therapeutic vaccine. (bvsalud.org)
Hematopoietic stem cell transplantation (HSCT) involves the intravenous infusion of hematopoietic stem cells in order to reestablish blood cell production in patients whose bone marrow or immune system is damaged or defective. (medscape.com)
7. Younan P, Iampietro M, Bukreyev A. Disabling of lymphocyte immune response by Ebola virus. (prolekarniky.cz)
Does the virus toll the bell for immune system? (prolekarniky.cz)
As the pathogenesis of viral illnesses is affected by host immune responses, various immune modulators have been proposed as biomarkers to predict the risk of the disease progression to a severe form, at a much earlier stage of the illness. (frontiersin.org)
GeoVax is at the forefront of development for a COVID-19 vaccine and its use of recombinant viruses to generate virus-like particles (VLPs) in vivo has demonstrated considerable immune response for other viruses in a number of human clinical trials. (gabio.org)
The production of VLPs in the person being vaccinated mimics virus production in a natural infection, stimulating both the humoral and cellular arms of the immune system to recognize, prevent, and control the target infection. (gabio.org)
The effective immune cells to eliminate the viral agents are cytotoxic T cell (Tc), natural killer cell (NK), and macrophage. (tci-thaijo.org)
Known as the adaptive immune cell, Tc plays the most crucial role in the immune clearance of the viral agent. (tci-thaijo.org)
Varicella zoster virus immune evasion strategies. (tci-thaijo.org)
Extracellular vesicles in Herpes viral spread and immune evasion. (tci-thaijo.org)
filovirus vaccine research efforts still need to determine the roles of humoral and cell-mediated immune responses in protection from ebola virus infection. (liverpool.ac.uk)
Measles virus infection in rhesus macaques: altered immune responses and comparison of the virulence of six different strains. (unt.edu)
The Fc receptor-dependent function of antibody-dependent cellular phagocytosis (ADCP) provides mechanisms for clearance of virus and virus-infected cells, as well as for stimulation of downstream adaptive immune responses by facilitating antigen presentation, or by stimulating the secretion of inflammatory mediators. (frontiersin.org)
We propose that additional investigation into the role of ADCP in protective viral responses, the specific virus epitopes targeted by ADCP antibodies, and the types of phagocytes and Fc receptors involved in ADCP at sites of virus infection will provide insight into strategies to successfully leverage this important immune response for improved antiviral immunity through rational vaccine design. (frontiersin.org)
Viruses with lipid envelopes have a greater ability to adhere to cell membranes and to avoid destruction by the immune system. (unboundmedicine.com)

Lassa fever hits West African countries annually in the absence of licensed vaccine to limit the burden of this viral hemorrhagic fever. (bvsalud.org)
We evaluated the safety, tolerability, and immunogenicity of a recombinant, live-attenuated, measles-vectored Lassa fever vaccine candidate (MV-LASV). (bvsalud.org)
Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ca Suffit! (prolekarniky.cz)
Despite efforts made over past decades, there is no vaccine or treatment available for preventing and controlling the ASF virus (ASFV) infection, and there is an urgent need to develop novel strategies. (mdpi.com)
Measles inclusion body encephalitis caused by the vaccine strain of measles virus. (unt.edu)
Now there is evidence from two separate cohorts of children, and two separate teams of researchers, that the vaccine strain measles virus is present in these children. (whale.to)

There are proposals to remove the virulent genes from viruses to create vaccines. (wikipedia.org)
AAVs are nonenveloped single-stranded DNA viruses used in gene therapy to insert copies of missing genes into host cells. (unboundmedicine.com)
In addition, since the gene encoding the A56 protein is non-essential, it can be used as an insertion point for foreign genes and has been deleted in some viruses that are in clinical development as oncolytic agents. (microbiologyresearch.org)

001), malaria ( P =.04), dengue fever ( P =.006), brucellosis ( P =.03), and tuberculosis ( P =.003) exhibited significant seasonal patterns. (jmir.org)

Inhibition of Nipah Virus by Defective Interfering Particles. (cdc.gov)
The expelling of virus particles from the body. (lookformedical.com)

Most of the therapeutic agents in this review are directed against non-mutable targets of the host, which is independent of viral mutation. (biomedcentral.com)

Ebola virus: the role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever. (prolekarniky.cz)

A virus commonly found in macaques (Old World monkeys) but not in other primates. (unboundmedicine.com)

human recombinant antibodies to ebola virus: preparation and characteristics]. (liverpool.ac.uk)
human recombinant antibodies against a purified ebola virus (ev) lysate were selected from a combinatorial library of scfv-antibodies using the phage display technique. (liverpool.ac.uk)

infection with ebola virus causes a severe disease accompanied by high mortality rates, and there are no licensed vaccines or therapies available for human use. (liverpool.ac.uk)

Her chief research interest is the development of viral-vectored vaccines that work by inducing strong and protective T and B cell responses. (isv-online.org)

In vitro and in vivo experiments have shown that Ebolavirus pathogenicity is multifactorial, including viral and host determinants. (biomedcentral.com)

daily laboratory studies (coagulation patients (3, 6, 7, and 18) would likely not be admitted to- studies, blood counts, chemistries, viral isolation, D-dimer) day: 2 involved dengue virus (now a BSL-2 pathogen) and and regular physician assessments were performed. (cdc.gov)
Dengue virus (DENV) is an enveloped, single-stranded RNA virus belonging to the Flaviviridae family. (frontiersin.org)

Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. (cdc.gov)

Most animal viruses are also surrounded by a lipid envelope (a bilayered membrane analogous to a cell membrane). (unboundmedicine.com)

Despite signs of increased vascular permeability, endothelial cell infection was not a determinant factor of the hemorrhagic syndrome. (bvsalud.org)
Purpura fulminans is a rare syndrome of intravascular thrombosis and hemorrhagic infarction of the skin that is rapidly progressive and is accompanied by vascular collapse and disseminated intravascular coagulation. (medscape.com)

Genetic variability of hepatitis E virus within and between three epidemics in India. (unt.edu)
Viruses, as experts know them now, consist of little more than strings of their own genetic information (DNA or RNA) housed in a protein shell. (patrickmalonelaw.com)
They appear in the genetic double-helix in patterns, captured in scientific terms by letter chains like A-T-C-G. Scientists have learned to map or sequence these, giving them i mportant new ways to detect and protect against viruses . (patrickmalonelaw.com)
Deoxyribonucleic acid that makes up the genetic material of viruses. (lookformedical.com)
Viruses whose genetic material is RNA. (lookformedical.com)
Virus A Rna 0 domande Viruses whose genetic material is RNA. (lookformedical.com)

Cytology of the BAL fluid was consistent with hemorrhagic lymphocytic alveolitis. (biomedcentral.com)

Viral hemorrhagic fevers (HF) are a group of acute febrile diseases with high mortality rates. (bvsalud.org)
. S-adenosylhomocysteine hydrolase inhibitors have been found to have complete mortality protection in mice infected with a lethal dose of Ebola virus (30). (saratoga.com)
We propose a therapeutic regimen to supplement the current supportive therapy aiming to reduce viral load, the most important factor in the determination of mortality. (biomedcentral.com)

Epidemics of viral myositis may temporarily increase the incidence in local areas. (medscape.com)

In clinical studies, arenaviruses such as Lassa, Machupo and Guanarito viruses caused HF that vary in symptoms and biological alterations. (bvsalud.org)
We found that lethal infection with Machupo, Guanarito and Lassa viruses is associated with cutaneo-mucosal, cerebral, digestive and pulmonary hemorrhages. (bvsalud.org)
BACKGROUND: Lassa fever is a substantial health burden in west Africa. (bvsalud.org)

Why are RNA virus mutation rates so damn high? (tci-thaijo.org)
But many viruses can exist in species for a long time and burgeon before they display another of their jaw-dropping attributes: mutation. (patrickmalonelaw.com)

we reviewed published reports on 254-nm uv inactivation and tabulated the sensitivities of a wide variety of viruses, including those with double-stranded dna, single-stranded dna, double-stranded rna, or single-stranded rna genomes. (liverpool.ac.uk)

This says that the best way to activate a gene in an endogenous retrovirus may well be to infect with a very similar exogenous virus. (phoenixrising.me)
New viruses are then released either by destroying their host cell or by forming small buds that break off and infect other cells. (unboundmedicine.com)

There have even been sporadic reports of mammary tumor virus in non-human primates. (phoenixrising.me)

Blydt-Hansen T, Subbarao K, Quennec P, McDonald J. Recovery of respiratory syncytial virus from stethoscopes by conventional culture and polymerase chain reaction. (unt.edu)

Major drawbacks of this therapy are that RBV is not approved for administration to pregnant women and that the virus can acquire mutations, which render the intra-host population less sensitive or even resistant to RBV. (mdpi.com)
Sometimes mutations can allow viruses to make a dramatic leap from one species to another, particularly if they are close by and have close contact with the original host. (patrickmalonelaw.com)

We present a potential exposure to Ebola virus that tamination of the site also reduced potential for infection. (cdc.gov)

Rabbitpox virus is a subspecies of VACCINIA VIRUS . (lookformedical.com)
The variola virus is a large, brick-shaped, double-stranded DNA virus that serologically cross-reacts with other members of the poxvirus family, including ectromelia, cowpox, monkeypox, vaccinia, and camelpox. (medscape.com)
Deletion of the A56R gene results in varying effects on vaccinia virus virulence. (microbiologyresearch.org)

People with Systemic Juvenile Idiopathic Arthritis (also known as Stills disease) can have recurrent fevers, a macular rash, joint pain, joint deformities, an enlarged liver and/or spleen, and can occasionally have polyserositis, lung involvement or pericardial effusions. (passmed.uk)

The term 'cytokine storm' entered the popular lexicon with previous influenza virus pandemics but has become even more mainstream because of the severe inflammation that can accompany SARS-CoV-2 infection 1 . (nature.com)

Rejecting a viral etiology out of hand would be unwise. (phoenixrising.me)

Substances elaborated by viruses that have antigenic activity. (lookformedical.com)

Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)

One of the proposed modes of action of RBV is a direct mutagenic effect on viral genomes, inducing mismatches and subsequent nucleotide substitutions. (mdpi.com)
Virus 1 quesito Minute infectious agents whose genomes are composed of DNA or RNA, but not both. (lookformedical.com)

Its newly launched ProVir TM collection is the world's largest viral antigen bank, carrying over 800 products from 350 strains of viruses. (gabio.org)
Such viruses are produced in cells coinfected with different strains of a given virus. (lookformedical.com)

A virus with reduced pathogenicity as a result of treatment or repeated passage through hosts. (unboundmedicine.com)

So far, efforts to develop effective drugs against these viruses have failed, and typical therapy usually relies on symptomatic treatment. (saratoga.com)

Recently, the Centers for Disease Control and Prevention issued its third Level 1 emergency response in nine years regarding this virus, which is reserved for the most dire health emergencies. (saratoga.com)
Interestingly, the Ebola virus is inactivated by UV radiation.12 It certainly isn't the first time sunlight has been shown to be beneficial in the fight against disease, although bacteria appears to be more susceptible to UV radiation than viruses. (saratoga.com)
4. Kilgore PE, Grabenstein JD, Salim AM, Rybak M. Treatment of ebola virus disease. (prolekarniky.cz)
The recent incursions of African swine fever (ASF), a severe, highly contagious, transboundary viral disease that affects members of the Suidae family, in Europe and China have had a catastrophic impact on trade and pig production, with serious implications for global food security. (mdpi.com)
Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL). (lookformedical.com)
Smallpox is an acute, contagious disease caused by the variola virus, a member of the genus Orthopoxvirus , in the Poxviridae family (see the image below). (medscape.com)
We have long thought of Alzheimer's as a disease of defective brain signaling," said Gandy, who had no role in the study. (blogspot.com)
Conceivably, there is also a disease of defective insulin signaling, which this paper would support. (blogspot.com)
When viruses enter a cell, they may immediately trigger a disease process or may remain quiescent for years. (unboundmedicine.com)

Anatomy2

Organisms20

Diseases20

Chemicals and Drugs5

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes5

Information Science2

Health Care1

Geographicals1

Replication11

Glycoprotein4

Infections17

Outbreaks4

Humans7

Proteins10

EBOV5

Antigens5

Genome6

Bacterial2

Chills1

Marburg4

Replicate8

Zika2

Vectors3

Cynomolgus4

Immune16

Vaccine6

Genes3

Brucellosis1

Particles2

Targets1

Pathogenesis1

Macaques1

Recombinant2

Infection with Ebola1

Vaccines1

Ebolavirus1

Dengue virus2

Nairovirus1

Lipid1

Syndrome2

Genetic6

Lymphocytic1

Mortality3

Epidemics1

Lassa3

Mutation2

Single-stranded1

Infect2

Sporadic1

Respiratory1

Mutations2

Exposure to Ebola virus1

Vaccinia3

Recurrent1

Influenza1

Etiology1

Antigenic1

Diseases caused1

Genomes2

Strains2

Pathogenicity1

Develop1

Disease9