• In the realm of organic chemistry, one class of compounds has captured the scientific community's attention for decades - alkaloids. (selfgrowth.com)
  • Alkaloids represent a large and diverse group of organic compounds characterized by the presence of a nitrogen-containing heterocyclic ring. (selfgrowth.com)
  • Alkaloids are a fascinating group of naturally occurring chemical compounds found in various plants, fungi, and some animals. (selfgrowth.com)
  • As a result, alkaloids find applications in various industries, including medicine, agriculture, and even the synthesis of fine chemicals. (selfgrowth.com)
  • Quinine, an alkaloid found in the bark of the cinchona tree, has been traditionally used as a natural remedy for malaria by interfering with the parasite's protein synthesis. (selfgrowth.com)
  • Breeding techniques have produced more than 100 varieties, with improved floral traits, increase tolerance to disease and alkaloid yield. (stuartxchange.org)
  • Vinca alkaloids are now produced synthetically and used as drugs in cancer therapy and as immunosuppressive drugs. (wikipedia.org)
  • Isoquinoline alkaloids - Isoquinoline alkaloids 1-Benzyl isoquinoline type: Papaverine: An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. (powershow.com)
  • Alkaloids such as morphine and codeine have been widely used as painkillers due to their powerful analgesic properties. (selfgrowth.com)
  • Artemisinin, an alkaloid extracted from Artemisia annua, revolutionized malaria treatment. (selfgrowth.com)
  • Alkaloids have demonstrated considerable potential in combatting various fungal pathogens, providing alternative treatment options for these debilitating infections. (selfgrowth.com)
  • Vinca alkaloid, used in the treatment of several types of cancer. (e-lactancia.org)
  • Vinca alkaloid derived from the periwinkle plant. (medscape.com)
  • 8. Cytotoxic aspidosperma-type alkaloids from Melodinus suaveolens. (nih.gov)
  • 10. Cytotoxic eburnamine-aspidospermine type bisindole alkaloids from Bousigonia mekongensis. (nih.gov)
  • 13. Melotenine A, a cytotoxic monoterpenoid indole alkaloid from Melodinus tenuicaudatus. (nih.gov)
  • Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. (nih.gov)
  • Vinca alkaloids inhibit microtubule formation, which in turn disrupts the formation of mitotic spindle, causing cell proliferation to arrest at metaphase. (medscape.com)
  • Vinca alkaloids act on the M and S phases of mitosis, inhibiting microtubule formation and inhibiting DNA/RNA synthesis. (medscape.com)
  • Normacusine B, a monomeric alkaloid of the corynanthe class, also found in Rauvolfia, Tabernaemontana and Vinca spp. (pfaf.org)
  • The National Cancer Institute defines vinca alkaloid as "a type of drug that blocks cell growth by stopping mitosis (cell division). (gardenguides.com)
  • Vinflunine is also a new synthetic vinca alkaloid, which has been approved in Europe for the treatment of second-line transitional cell carcinoma of the urothelium is being developed for other malignancies. (nih.gov)
  • Veratrum species contain highly toxic steroidal alkaloids (e.g. veratridine) that activate sodium ion channels and cause rapid cardiac failure and death if ingested. (google.com)
  • In the winter months, the plant degrades and metabolizes most of its toxic alkaloids. (google.com)