• METHODS: FAME 3 (Fractional Flow Reserve versus Angiography for Multivessel Evaluation) is an investigator-initiated, multicenter, international, randomized trial involving patients with 3-vessel coronary artery disease (not involving the left main coronary artery) in 48 centers worldwide. (ox.ac.uk)
  • The aim of the RENOVATE study was to determine whether the use of intravascular imaging in addition to angiography would lead to better outcomes, compared with angiography alone, in patients with complex coronary artery blockages. (dicardiology.com)
  • Strengths of the study are its larger sample size and longer follow-up period than previous studies comparing imaging- and angiography-guided stenting, as well as its inclusion of patients with various types of complex coronary artery blockages, Hahn said. (dicardiology.com)
  • Compared to CMR, coronary computed tomographic angiography (CCTA) provides more precise assessment of coronary anatomy, course and degree of stenosis, but its clinical use for screening is strongly limited by its cost, the need for ionizing radiation, intravenous contrast and, in many cases, drugs administration. (wikipedia.org)
  • Forty-five patients underwent low-dose DSE and invasive coronary angiography with IMR measurement in the left anterior descending artery. (nih.gov)
  • Coronary computed tomography angiography (CCTA) is a noninvasive method to image the coronary arteries. (medscape.com)
  • Coronary artery anomalies in 126,595 patients undergoing coronary angiography. (scirp.org)
  • Coronary artery anomalies: Assessment with free-breathing three-dimensional coronary MR angiography. (scirp.org)
  • Methods: The current study is an analysis of prospectively enrolled randomly selected patients with known stable CAD, who were taking aspirin (75-100 mg qd) regularly for at least one month, and had undergone coronary angiography at least 3 months prior to the enrollment to the study. (bgu.ac.il)
  • 50% stenosis in ≥2 separate major coronary territories per coronary angiography. (bgu.ac.il)
  • Angiography revealed normal coronary arteries. (biomedcentral.com)
  • CT coronary angiography can detect coronary plaque with high resolution, estimate the degree of functional stenosis and characterise plaque features. (bmj.com)
  • Consequently, invasive coronary angiography (ICA) became the gold standard for diagnosis of CAD. (bmj.com)
  • There are new recommendations for the use of coronary computed tomographic angiography (CCTA) from the Society of Cardiovascular Computed Tomography (SCCT). (diagnosticimaging.com)
  • CTA is appropriate for coronary artery evaluation before non-coronary cardiac surgery as an equivalent alternative to invasive angiography in patients with low-to-intermediate probability of CAD and younger patients with primarily non-degenerative valvular conditions. (diagnosticimaging.com)
  • Therefore, we sought to explore the actual causes of death and their relation with progressive coronary atherothrombosis documented by coronary angiography or autopsy in a large Japanese observational database of patients undergoing first coronary revascularization. (crtonline.org)
  • Methods: Among 562 patients from FRAME-AMI trial who were randomly allocated into either FFR-guided or angiography-guided PCI for non-IRA lesions, the current study evaluated the relationship between non-IRA stenosis measured by quantitative coronary angiography (QCA) and the efficacy of FFR-guided PCI. (bvsalud.org)
  • OBJECTIVE: To assess the accuracy of a virtual stenting tool based on coronary CT angiography (CCTA) and fractional flow reserve (FFR) derived from CCTA (FFRCT Planner) across different levels of image quality. (bvsalud.org)
  • KEY POINTS: â ¢ The fractional flow reserve derived from coronary CT angiography (FFRCT) Planner is a novel tool able to accurately predict fractional flow reserve after percutaneous coronary intervention. (bvsalud.org)
  • Subject suffering from coronary artery disease requiring percutaneous coronary angiography and/or intervention. (who.int)
  • Coronary angiography and/or intervention contraindications. (who.int)
  • The left coronary artery (typically called the left main coronary artery) branches into the circumflex and the left anterior descending artery. (msdmanuals.com)
  • The left coronary artery soon divides, giving off this circumflex branch, and several branches to the left ventricle, the longest of which is the left interventricular artery, also called the left anterior descending artery. (aclandanatomy.com)
  • The insertion of a stent (a tiny metal tube, usually coated with slow-release medication to help prevent repeat narrowing or blockage) into a coronary artery is a minimally invasive alternative to cardiac bypass surgery for people with a coronary artery that is blocked or partially blocked by a buildup of fatty deposits (plaque). (dicardiology.com)
  • People with such complex coronary artery blockages are at increased risk for experiencing a heart attack or a blood clot in a stent or for needing a repeat stenting procedure. (dicardiology.com)
  • Syntax Study results (www.syntaxtrial.com) comparing Myocardial Revascularization Surgery against Angioplasty plus Stent in Patients with Left Main Trunk lesions plus 2 or 3 coronary vessels disease, showed that long-term mortality is comparable with both techniques. (drrobertocarlocorrea.com)
  • 9. Stent supported coronary angioplasty in patients with severe ventricular dysfunction / C. Li, G. Jia, W. Guo [et al. (org.ua)
  • 10. Revascularization in severe left ventricular dysfunction: outcome comparison of drug-eluting stent implantation versus coronary artery by-pass grafting / G. Gioia, W. Matthai, K. Gillin [et al. (org.ua)
  • A coronary artery stent is a small, metal mesh tube that expands inside a coronary artery. (medlineplus.gov)
  • BACKGROUND: Intravascular ultrasound (IVUS) has several benefits during percutaneous coronary interventions (PCIs), including more accurate vessel sizing, improved stent expansion, and better strut apposition. (johnshopkins.edu)
  • Cumulative incidences of cardiac death, target vessel myocardial infarction, and clinically indicated target lesion revascularization and definite stent thrombosis at 5 years were similar in patients treated with ultrathin-strut BP-SES and thin-strut DP-EES. (ox.ac.uk)
  • CCTA is appropriate in symptomatic patients with intra-coronary stent diameters great than or equal to 3.0 mm, implementing measures to improve stent imaging accuracy, such as heart-rate control, iterative, sharp kernel, and mono-energetic reconstruction. (diagnosticimaging.com)
  • Coronary stent restenosis and the association with allergy to metal content of 316L stainless steel. (cdc.gov)
  • IVUS consists of cross-sectional imaging of coronary arteries in a catheterization laboratory by advancing a thin probe inside the vascular lumen, obtaining precise in-vivo information about degree of area stenosis in different arterial segments, providing a solid basis for treatment strategies. (wikipedia.org)
  • However, coronary artery disease risk is also driven by biological processes, such as inflammation, that are not fully reflected by severity of stenosis, myocardial ischaemia or by coronary plaque features. (bmj.com)
  • In line with the ageing population, the prevalence of coronary artery disease (CAD), lower extremity peripheral arterial disease (PAD), supra-aortic arterial disease (SAD) and renal stenosis (RAS) is increasing. (who.int)
  • Besides, the results of coronarography in patients with ICD with marked systolic dysfunction of LV gives evidence for LCA stem lesions with multivessels involvement of coronary arteries with predominant type C proximal level of lesion. (org.ua)
  • The use of IVUS for complex lesions was associated with lower risk of medium-term mortality and target vessel revascularization. (johnshopkins.edu)
  • MATERIALS AND METHODS: Prospective, multicenter, single-arm study of patients with chronic coronary syndromes and lesions with FFR ≤ 0.80. (bvsalud.org)
  • MTHFR C677T gene polymorphism and the severity of coronary lesions in acute coronary syndrome. (cdc.gov)
  • Genetic risk of restenosis after percutaneous coronary interventions in the era of drug-eluting stents. (cdc.gov)
  • 6. Inducible myocardial ischemia and outcomes in patients with coronary artery disease and left ventricular dysfunction / J. A. Panza, T. A. Holly, F. M. Asch [et al. (org.ua)
  • We sought to assess the long-term effect of ultrathin-strut (60 μm) BP-SES versus thin-strut (81 μm) DP-EES on long-term outcomes in patients undergoing percutaneous coronary revascularization for small vessel disease. (ox.ac.uk)
  • Long-Term Effect of Ultrathin-Strut Versus Thin-Strut Drug-Eluting Stents in Patients With Small Vessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the BIOSCIENCE Randomized Trial. (ox.ac.uk)
  • The work is dedicated for studying radiologic-angiographic features of coronary vessels in patients with ischemic heart disease (IHD) and decreased of left ventricle ejection fraction (LV EF) for reasonable treatment consideration of such patients group. (org.ua)
  • High On-Treatment Platelet Reactivity Determinants on Dual Antiplatelet Therapy in Patients With Ischemic Heart Disease Before Elective Percutaneous Coronary Intervention]. (cdc.gov)
  • Lunawave is an Optical Frequency Domain Imaging (OFDI) system to be used with a dedicated FastView coronary catheter for imaging and visualizing the coronary artery lumen and the vessel surface layer. (terumo-europe.com)
  • The guiding catheter is intended to be used in the coronary or peripheral vascular system. (medtronic.com)
  • Due to the size and relative stiffness of the guiding catheters, extreme care must be taken to avoid damage to the wall of the vessels through which this catheter passes. (medtronic.com)
  • Due to the size of the non-tapered tip, this catheter may occlude smaller vessels. (medtronic.com)
  • Inject slowly whenever attempting to opacify the vessels via this catheter. (medtronic.com)
  • A small tube is inserted into the groin and a long catheter is advanced into the heart and blood vessels. (weillcornell.org)
  • X-ray equipment is used to monitor the course of the catheter, and to document specific images that are acquired during the procedure, such as angiograms (which is the injection of a contrast agent into the chambers of the heart and/or great vessels). (weillcornell.org)
  • A thin, flexible tube (catheter) is inserted through the radial artery in the hand and into the heart and its blood vessels. (medicinenet.com)
  • Our study shows that the use of intravascular imaging devices to visualize the interior of narrowed coronary arteries improves outcomes after stenting," said Joo-Yong Hahn, MD, PhD , professor of cardiology and medicine at Sungkyunkwan University School of Medicine in Seoul, South Korea, and lead author of the study. (dicardiology.com)
  • Unstable Angina) Acute coronary syndromes result from a sudden blockage in a coronary artery. (msdmanuals.com)
  • This may be because a blockage is unusually long, calcified or located in a difficult-to-reach spot such as near the junction of the coronary artery and the aorta. (dicardiology.com)
  • Risk-adjusted mortality and target vessel revascularization were compared. (johnshopkins.edu)
  • This study sought to evaluate what proportion of death after coronary revascularization is related to documented progressive coronary atherothrombosis. (crtonline.org)
  • Documented progressive coronary atherothrombosis as the cause of death was defined as preceding coronary revascularization within 30 days before death or irreversible brain damage and/or proof of coronary thrombus by autopsy. (crtonline.org)
  • Only about one-third of deaths were cardiac in origin during 5-year follow-up in post-discharge patients after coronary revascularization. (crtonline.org)
  • This study demonstrated the causes of death after first coronary revascularization in Japanese cohort data. (crtonline.org)
  • The anatomical SYNTAX (Synergy between percutaneous coronary intervention with taxus and cardiac surgery) score (SxS) is an angiographic scoring system for assessing the complexity of coronary artery disease (CAD) [ 1 ] advocated for decision making in the latest ESC/EACTS guidelines on myocardial revascularization [ 2 ]. (hindawi.com)
  • Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography. (scirp.org)
  • A giant left circumflex coronary artery-right atrium arteriovenous fistula detected by multislice spiral computed tomography. (scirp.org)
  • Even subtle perturbations in this process may lead to congenital coronary artery anomalies, as occur in 0.2-1.2% of the general population (von Kodolitsch et al. (ox.ac.uk)
  • Coronary arteriovenous fistulas are anomalies at the termination consisting of an anomalous connection of coronary arteries to coronary veins, veins of the pulmonary or systemic circulations, or to any cardiac cavity. (wikipedia.org)
  • Carriers of coronary artery anomalies may receive positive results following stress/imaging tests. (wikipedia.org)
  • However, only in a minority of cases ischemia in the context of coronary artery anomalies is reproducible by stress or imaging testing and is mainly associated with particular conditions such as intense (maximal) exercise, which may lead to confusing results and misdiagnosis by techniques such as treadmill test or nuclear testing. (wikipedia.org)
  • Various imaging tests have a potential to identify coronary artery anomalies. (wikipedia.org)
  • Cardiac magnetic resonance (CMR) is an excellent tool to identify coronary artery anomalies with a significantly higher diagnostic accuracy than standard echocardiography. (wikipedia.org)
  • anomalies at the termination (such as coronary arteriovenous fistulas). (wikipedia.org)
  • Coronary vascular anomalies occur in ~1% of the population and lead to myocardial ischemia, infarction and heart failure. (pcom.edu)
  • Identification of molecular signals and cell origins of coronary vascular smooth muscle and endothelial cells during coronary vasculogenesis are key to understanding these anomalies. (pcom.edu)
  • Anomalies of the coronary arteries. (scirp.org)
  • CTA is appropriate for the evaluation of coronary anomalies. (diagnosticimaging.com)
  • Angioplasty is a procedure to open narrowed or blocked blood vessels that supply blood to the heart. (medlineplus.gov)
  • Keywords: Angioplasty Coronary artery disease Medicines Operation Survival Réamounté HISTORIQUE On n'est pas particular de la meilleure stratégie thérapeutique put les individuals atteints d'une coronaropathie bitronculaire avec atteinte de l'artère descendante antérieure gauche proximale (C2T+DAGP). (siamtech.net)
  • Lesion reference to AHA types V and VI was discarded, because it failed to account for the 3 different morphologies (rupture, erosion, and calcified nodule) that give rise to acute coronary thrombosis. (medscape.com)
  • Oxygen-poor systemic blood reaches the right atrium via 3 major venous structures: the superior vena cava, inferior vena cava, and coronary sinus. (medscape.com)
  • We present the case of a patient with diabetic ketoacidosis and hyperkalemia whose initial ECG showed a pseudoinfarction pattern, but an urgent coronary angiogram revealed normal coronary arteries. (biomedcentral.com)
  • CCTA image quality was adjudicated using the four-point Likert scale at a per-vessel level by an independent committee blinded to the FFRCT Planner. (bvsalud.org)
  • It has been suggested that hyperkalemia causes the 'pseudoinfarction' pattern not only through its direct myocardial effects, but also through other mechanisms, such as anoxia, acidosis, and coronary artery spasm. (biomedcentral.com)
  • In our patient, coronary spasm did not contribute to such an electrocardiography finding. (biomedcentral.com)
  • Additionally, long-term excessive sustained exercise may be associated with coronary artery calcification, diastolic dysfunction, and large-artery wall stiffening. (nih.gov)
  • CCT imaging for CAD initially quantified coronary artery calcification, as it was readily detected on CT images, and quantified to generate a coronary artery calcium score (CACS) that represented a surrogate marker of the presence and extent of CAD. (bmj.com)
  • The right coronary artery and the left coronary artery, which branch off the aorta just after it leaves the heart, deliver oxygen-rich blood to the heart muscle. (msdmanuals.com)
  • The abnormal origin of the right coronary artery from the left aortic sinus coursing between the aorta and the pulmonary trunk is a rare congenital anomaly. (scirp.org)
  • Close to the heart, the two main coronary arteries branch off of your aorta. (stlukesonline.org)
  • The right and left coronary arteries branch from the ascending aorta and, through their branches (anterior and posterior interventricular, marginal and circumflex arteries), supply the heart muscle (myocardial) tissue. (medscape.com)
  • The right coronary artery gives off this branch to the upper part of the right atrium, then runs downwards in the right atrio-ventricular groove, giving off branches to the right ventricle. (aclandanatomy.com)
  • The right coronary artery supplies blood to the right ventricle. (stlukesonline.org)
  • Ten specimens of saphenous veins were obtained from 10 patients admitted to the Heart Surgery Centre of P. Stradiņš Clinical University Hospital for coronary artery bypass surgery and a histopathological study was conducted. (utlib.ee)
  • The results of our trial may lead to an increase in the use of intravascular imaging-and, in turn, an improvement in clinical outcomes-among patients with complex coronary blockages who are undergoing stenting," Hahn said. (dicardiology.com)
  • 1% of the clinical population, and characterized by an intramyocardial course of coronary arteries within the muscle fibers. (wikipedia.org)
  • N. Söylemez, R. Demirbağ, T. Hazırolan and O. AkpınarP, "Anomalous Origin of the Right Coronary Artery from the Left Sinus Valsalva with Coronary Ectasia," International Journal of Clinical Medicine , Vol. 2 No. 3, 2011, pp. 269-271. (scirp.org)
  • Cardiac imaging is central to the diagnosis and risk stratification of coronary artery disease, beyond symptoms and clinical risk factors, by providing objective evidence of myocardial ischaemia and characterisation of coronary artery plaque. (bmj.com)
  • Coronary artery disease risk assessment that incorporates clinical factors, plaque characteristics and perivascular inflammation offers a more comprehensive individualised approach to quantify and stratify coronary artery disease risk, with potential healthcare benefits for prevention, diagnosis and treatment recommendations. (bmj.com)
  • 3 mm, respectively) did not stratify according to vessel size and failed to specify the impact of ultrathin-strut thickness on long-term clinical outcomes compared with durable polymer everolimus-eluting stents (DP-EES). (ox.ac.uk)
  • CONCLUSIONS: We found no significant difference in clinical outcomes throughout 5 years between patients with small vessel disease treated with ultrathin-strut BP-SES versus thin-strut DP-EES. (ox.ac.uk)
  • Later on, the SxS was applied to a variety of patient populations with diverse clinical presentations including those with acute coronary syndromes (ACS) undergoing primary PCI [ 5 , 6 ]. (hindawi.com)
  • Therefore, in order to account for the variability of clinical parameters affecting long-term outcomes and hence better classification of patients' risk, the SYNTAX score II (SxSII) was developed by complementing SxS with 7 prognostic variables including age, creatinine clearance, left ventricular ejection fraction (LVEF), presence of unprotected left main coronary artery (ULMCA) disease, peripheral vascular disease (PVD), female gender, and chronic obstructive pulmonary disease (COPD) [ 9 ]. (hindawi.com)
  • Impact of CYP2C19 polymorphism on clinical outcome following coronary stenting is more important in non-diabetic than diabetic patients. (cdc.gov)
  • Intravascular imaging, using ultrasound (IVUS) or optical coherence tomography, reveals that angiographic assessment of the coronary lumen grossly underestimates the presence, nature and extent of coronary artery plaque. (bmj.com)
  • EKG is appropriate for gate aortic dissection, aneurysm CTA, pulmonary embolus studies in men over age 45 and women over age 55, as well as analyze and report the coronary arteries. (diagnosticimaging.com)
  • The internal wall of the right atrium is composed of a smooth posterior portion (into which the vena cavae and coronary sinus drain) and a ridgelike, muscular anterior portion. (medscape.com)
  • The thebesian valve is located at the orifice of the coronary sinus. (medscape.com)
  • As we saw earlier, the coronary sinus ends by entering the underside of the right atrium, here. (aclandanatomy.com)
  • Here's the coronary sinus in an intact heart. (aclandanatomy.com)
  • The coronary sinus passes around the left atrioventricular groove to the underside of the heart. (aclandanatomy.com)
  • Coronary veins from the right side of the heart also empty into the coronary sinus. (aclandanatomy.com)
  • We evaluated whether left ventricular contractile reserve (CR), measured with strain imaging on dobutamine echocardiography (DSE), is a reliable non-invasive measure of coronary microvascular function. (nih.gov)
  • Coronary atherosclerotic disease is a leading cause of mortality and morbidity due to major cardiovascular events in the United States and abroad. (bvsalud.org)
  • Coronary microvascular function has important diagnostic and prognostic implications but routine assessment is difficult. (nih.gov)
  • Here, we report that a nanoparticle with a polysaccharide supramolecular core and a shell of amorphous-like hydrous ferric oxide generating strong T 1 MRI contrast (with a relaxivity coefficient ratio of ~1.2) facilitates the imaging, at resolutions of the order of a few hundred micrometres, of cerebral, coronary and peripheral microvessels in rodents and of lower-extremity vessels in rabbits. (nature.com)
  • Fig. 6: SAIO-enhanced MRI images of the lower-extremity vessels of a New Zealand rabbit. (nature.com)
  • When the need for regeneration arises, for example in the setting of coronary artery disease, a reactivation of embryonic processes ensues, redeploying many of the same molecular regulators. (ox.ac.uk)
  • Thus, an understanding of the mechanisms of embryonic coronary vasculogenesis and angiogenesis may prove invaluable in developing novel strategies for cardiovascular regeneration and therapeutic coronary angiogenesis. (ox.ac.uk)
  • PE-specific deletion of Tbx5 impairs epicardium and coronary vessel formation in embryonic mouse hearts and reduces expression of Reln mRNA that encodes the Reelin extracellular matrix glycoprotein. (pcom.edu)
  • Reelin is expressed in the PE and epicardium as well as nascent and mature coronary vessels of embryonic mouse hearts. (pcom.edu)
  • The goals of restorative intervention for individuals experiencing coronary artery disease (CAD) consist of symptomatic improvement avoidance of disease development and success benefits. (siamtech.net)
  • These results provide contemporary data to allow improved shared decision-making between physicians and patients with 3-vessel coronary artery disease. (ox.ac.uk)
  • 4. Myocardial viability and impact of surgical ventricular reconstruction on outcomes of patients with severe left ventricular dysfunction undergoing coronary artery bypass surgery: results of the Surgical Treatment for Ischemic Heart Failure trial / T. A. Holly, R. O. Bonow, J. M. Arnold [et al. (org.ua)
  • RESULTS: Among 2109 patients, 1234 (59%) were treated for small vessel disease. (ox.ac.uk)
  • Dominant causes of cardiac death in post-discharge patients included heart failure (10.0%) and sudden cardiac death (9.1%), both without apparent relation with progressive coronary atherothrombosis. (crtonline.org)
  • The aim of the present study was to assess the predictive performance of SxSII in patients presenting with ACS undergoing PCI and to compare it to the previously validated SxS and the commonly used Global Registry of Acute Coronary Events (GRACE) risk score [ 13 ]. (hindawi.com)
  • RESULTS: Overall, 120 patients (123 vessels) were included. (bvsalud.org)
  • OBJECTIVES: The purpose of this study was to evaluate the benefits of clopidogrel across high-risk subgroups METHODS: This was a post hoc analysis of the HOST-EXAM (Harmonizing Optimal Strategy for Treatment of coronary artery diseases-EXtended Antiplatelet Monotherapy) trial that randomly assigned patients who were event free for 6 to 18 months post-PCI on dual antiplatelet therapy (DAPT) to clopidogrel or aspirin monotherapy. (bvsalud.org)
  • The Diagnostic Utility of the Point-of-Care CYP2C19 Genotyping Assay in Patients with Acute Coronary Syndrome Dosing Clopidogrel: Comparison with Platelet Function Test and SNP Genotyping. (cdc.gov)
  • Association between high on-treatment platelet reactivity and occurrence of cerebral ischemic events in patients undergoing percutaneous coronary intervention. (cdc.gov)