Anti-neutrophil cytoplasmic antibodPolyarteritis nodosaLeukocytoclasticMedium-sized blood vesselsInflammationUrticarial vasculitisRenal vasculitisCutaneousAntineutrophilPredominantlyLarge vesselsManifestationsBiopsyThrombophlebitisAffectsVascularStenosisMalignanciesRheumatologyPrimaryDiseasesSmallKawasakiClinicalHepatitisPatientsBloodSecondaryGastrointestinalOrganCommon
Anti-neutrophil cytoplasmic antibod1
- Coughlan AM, Freeley SJ, Robson MG. Animal models of anti-neutrophil cytoplasmic antibody-associated vasculitis. (smw.ch)
Polyarteritis nodosa5
- [6] Takayasu's arteritis is an example of a large-vessel vasculitis in childhood, whereas Kawasaki disease and polyarteritis nodosa are examples of medium-vessel vasculitis disorders. (scielo.org.za)
- The image below depicts nodules in cutaneous polyarteritis nodosa (PAN), a systemic vasculitis characterized by necrotizing inflammatory lesions that affect medium-sized and small muscular arteries. (medscape.com)
- For example, Kawasaki disease is characterized by a mucocutaneous syndrome and coronary artery inflammation, whereas polyarteritis nodosa (PAN), another medium-vessel vasculitis, manifests with nodular skin lesions, neuropathy, and hypertension. (medscape.com)
- In this cross-sectional study, 25-hydroxy (OH) vitamin D3 levels were measured in adult patients with systemic small and medium vessel vasculitis including antineutrophil cytoplasmic antibody-associated vasculitis (AAV), cryoglobulinaemic vasculitis (CryV), IgA vasculitis (IgAV) and polyarteritis nodosa (PAN), and age- and sex-matched healthy subjects (HS) and patients with rheumatoid arthritis (RA) as control groups. (reumatologiaclinica.org)
- It has been reported that one vasculitides such as for example HSV and polyarteritis nodosa (Skillet) are even more common among familial Mediterranean fever (FMF) sufferers [9-14]. (cell-signaling-pathways.com)
Leukocytoclastic5
- Leukocytoclastic vasculitis. (medscape.com)
- findings include leukocytoclastic vasculitis . (amboss.com)
- The evaluation of a patient with leukocytoclastic vasculitis (LCV) serves two purposes. (medscape.com)
- Immunofixation electrophoresis is useful to identify subtle paraproteinemia that has been reported in some patients with leukocytoclastic vasculitis. (medscape.com)
- A skin biopsy of a relatively new lesion should be performed in most adult patients with suspected leukocytoclastic vasculitis (LCV). (medscape.com)
Medium-sized blood vessels2
- The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small- to medium-sized blood vessels. (smw.ch)
- [ 1 ] Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small- and medium-sized blood vessels. (medscape.com)
Inflammation5
- We sought to test the ability of contrast-enhanced, high-resolution 3D vessel wall MR imaging to identify vascular inflammation and direct open biopsies of intracranial target vessels and adjacent brain parenchyma. (ajnr.org)
- We operationally define central nervous system vasculitis (CNSV) as any inflammatory vasculopathy producing nonatheromatous inflammation of intracranial vessels either directly (eg, primary CNS vasculitis) or indirectly via inflammation of CNS parenchyma with secondary vascular involvement (eg, as seen with infections, tumors, and certain autoimmune conditions). (ajnr.org)
- Vasculitis is defined as inflammation of the wall of blood vessels. (scielo.org.za)
- The overall goal of treatment is control of vessel inflammation and prevention of irreversible vascular and organ damage. (scielo.org.za)
- The clinical presentation varies according to the histologic type of inflammation, the size of the involved blood vessel segment, and the distribution of the involved vessels. (medscape.com)
Urticarial vasculitis3
- In patients with suspected systemic lupus erythematosus or urticarial vasculitis, complement levels should be obtained, including total hemolytic complement (CH100 or CH50), C3 levels, and C4 levels. (medscape.com)
- Patients with hypocomplementemic urticarial vasculitis syndrome, and less commonly in those with systemic lupus erythematosus, often have circulating anti-C1q antibodies with concomitant low levels of C1q. (medscape.com)
- Pulmonary function tests should be obtained in patients with hypocomplementemic urticarial vasculitis syndrome (HUVS) to assess for chronic obstructive pulmonary disease. (medscape.com)
Renal vasculitis2
- The clinical spectrum of primary renal vasculitis. (medscape.com)
- This medical program may be seen in any form of GN including poststreptococcal glomerulonephritis, renal vasculitis, HSV. (cell-signaling-pathways.com)
Cutaneous2
- Cutaneous small-vessel vasculitis is often idiopathic , but all patients should be evaluated for potential underlying causes, including infections (e.g. (amboss.com)
- The pathological mechanism that causes cutaneous small-vessel vasculitis can also cause vasculitides in organs other than the skin , which are categorized as distinct diseases. (amboss.com)
Antineutrophil2
- Cartin-Ceba R, Fervenza FC, Specks U. Treatment of antineutrophil cytoplasmic antibody-associated vasculitis with rituximab. (smw.ch)
- A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. (smw.ch)
Predominantly2
- The predominantly large vessel vasculitis is Takayasu arteritis. (medscape.com)
- Predominantly small vessel vasculitis is divided into granulomatous and nongranulomatous. (medscape.com)
Large vessels1
- Characteristic clinical features are caused by stenotic large vessels and subsequently decreased blood supply to the organ systems. (medscape.com)
Manifestations4
- We report a rare case of neonatal vasculitis presenting with skin manifestations similar to infection-based cellulitis. (scielo.org.za)
- As such, the classification of childhood vasculitides incorporates both vessel size and organ manifestations. (medscape.com)
- CNS manifestations include vasculitis of small to medium-sized vessels of the brain or spinal cord and granulomatous masses that involve the orbit, optic nerve, meninges, or brain. (medscape.com)
- As such, the most recent classification of childhood vasculitides incorporates both vessel size and organ manifestations. (medscape.com)
Biopsy5
- We conclude that vessel wall MR imaging can identify inflamed intracranial vessels, enabling precise localization of biopsy targets. (ajnr.org)
- We hypothesized that vessel wall MR imaging (VWMRI) 14 can identify inflamed intracranial vessels and precisely localize biopsy targets, thus aiding in the diagnosis of CNSV and its attendant pathology. (ajnr.org)
- Skin biopsy revealed small and intermediate vessel vasculitis. (scielo.org.za)
- Vasculitis was reported as the cause of death on postmortem biopsy. (scielo.org.za)
- A epidermis biopsy demonstrated a leucytoclastic deposition and vasculitis of IgA. (cell-signaling-pathways.com)
Thrombophlebitis1
- Vasculitis and thrombophlebitis. (medscape.com)
Affects1
- Note that the main large vessel vasculitis that affects children is Takayasu arteritis , and that temporal arteritis is not seen in the pediatric population. (medscape.com)
Vascular2
- The classification and severity of disease are determined based on the size and site of involved vessels, underlying pathophysiology and the extent of vascular injury. (scielo.org.za)
- Preferred sites of vascular involvement by selected vasculitides. (medscape.com)
Stenosis1
- It may result in vessel wall thickening, stenosis, and occlusion with subsequent ischemia. (medscape.com)
Malignancies2
- However, the incidence of malignancies in systemic vasculitis is relatively unknown. (nature.com)
- However, information regarding the risk of malignancies in patients with large-vessel vasculitis remains scarce. (nature.com)
Rheumatology1
- These criteria represent a modification and adaptation of existing American College of Rheumatology and Chapel Hill criteria for vasculitis in adults. (medscape.com)
Primary5
- The neonatal period is an uncommon time for the presentation of vasculitis and primary neonatal vasculitis is a particularly rare entity. (scielo.org.za)
- This article focuses on the primary systemic vasculitides of childhood. (medscape.com)
- Other subtypes of primary childhood vasculitis are much rarer. (medscape.com)
- Practitioners may find it helpful to think of primary systemic vasculitides based on the predominant size of the involved vessels, as suggested by the Chapel Hill Classification. (medscape.com)
- EULAR recommendations for the management of primary small and medium vessel vasculitis. (smw.ch)
Diseases2
- Central nervous system vasculitides are elusive diseases that are challenging to diagnose because brain biopsies have high false-negative rates. (ajnr.org)
- However, an overlap of vessel sizes affected within the diseases is noted, and the phenotype and pattern of organ involvement in vasculitis seems to be independent of vessel size. (medscape.com)
Small6
- Small-vessel vasculitis. (medscape.com)
- Henoch-Schonlein purpura is a vasculitic process involving small vessels. (scielo.org.za)
- To determine the prevalence of vitamin D deficiency in patients with small and medium vessel systemic vasculitis. (reumatologiaclinica.org)
- Henoch-Schonlein Vasculitis (HSV) is definitely systemic small vessel vasculitis involving the pores and skin, kidney, bones, and gastrointestinal tract. (cell-signaling-pathways.com)
- Among systemic vasculitis, small-vessel vasculitis has been the most frequently studied. (nature.com)
- Gomez-Puerta JA, Bosch X. Anti-neutrophil cytoplasmic antibody pathogenesis in small-vessel vasculitis: an update. (smw.ch)
Kawasaki2
- The most common forms of systemic vasculitis in children are Henoch-Schonlein purpura (HSP) and Kawasaki disease (KD). (medscape.com)
- The most common forms of systemic vasculitis in children are Henoch-Schoenlein purpura (HSP) and Kawasaki disease (KD). (medscape.com)
Clinical1
- See Vasculitis: Case Presentations , a Critical Images slideshow, for more information on clinical, histologic, and radiographic imaging findings in various forms of vasculitis. (medscape.com)
Hepatitis1
- Known causes of vasculitis include the following: infections (hepatitis B and Streptococcus spp. (scielo.org.za)
Patients5
- Fiducial markers were placed, and a standardized MR imaging protocol was implemented for all patients that included a 3D time-of-flight MRA (acquired resolution, 0.5 × 0.5 × 0.55 mm 3 ), pre- and postcontrast 3D VWMRI (acquired resolution, 0.5 × 0.5 × 0.5 mm 3 ), and a 3D contrast-enhanced MRA (acquired resolution, 0.52 × 0.52 × 1.04 mm 3 ) of the intracranial vessels (On-line Fig 1). (ajnr.org)
- Skin eruptions may be a symptom of systemic disorders other than infections, and may be prominent in patients with vasculitis disorders. (scielo.org.za)
- Comparison of vasculitis patients with and without vitamin D replacement. (reumatologiaclinica.org)
- Fifty-seven patients (42 AAV, 2 CryV, 8 IgA vasculitis, 5 PAN) with systemic vasculitis, 101 HS, and 111 RA patients were included. (reumatologiaclinica.org)
- Risk of venous thromboembolism among patients with vasculitis: a systematic review and meta-analysis. (cdc.gov)
Blood1
- Disease severity is dictated by the location and extent of the blood vessels affected. (smw.ch)
Secondary1
- Vasculitis can also occur secondary to another disease, and this should be ruled out. (medscape.com)
Gastrointestinal1
- History Henoch-Sch?nlein Vasculitis (HSV) is systemic little vessel vasculitis relating to the epidermis, kidney, joint parts, and gastrointestinal system. (cell-signaling-pathways.com)
Organ1
- Vasculitis can involve vessels of any size and can affect any organ system. (medscape.com)
Common1
- Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy. (cdc.gov)